Overview

ID MAG03200
Name PYH2_bin.57
Sample SMP0074
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order TCS64
Family TCS64
Genus UBA8941
Species
Assembly information
Completeness (%) 68.7
Contamination (%) 0.37
GC content (%) 37.0
N50 (bp) 4,023
Genome size (bp) 1,261,819

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1299

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_100681_0 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.00000000000000000000000000000000000000000000004088 177.0
PYH2_k127_100681_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000003376 92.0
PYH2_k127_100681_2 Signal transduction protein with CBS domains - - - 0.000000000000001141 82.0
PYH2_k127_1014455_0 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000007824 168.0
PYH2_k127_1014455_1 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000001099 108.0
PYH2_k127_1014455_2 Belongs to the serpin family K13963 - - 0.0000000000000001154 86.0
PYH2_k127_1014455_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00001498 54.0
PYH2_k127_10150_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 1.542e-239 758.0
PYH2_k127_10150_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 512.0
PYH2_k127_10150_2 Catalyzes the condensation of pyruvate and acetyl- coenzyme A to form (R)-citramalate K09011 - 2.3.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 512.0
PYH2_k127_10150_3 COG1921 Selenocysteine synthase seryl-tRNASer selenium transferase K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000009641 218.0
PYH2_k127_10150_4 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000009229 164.0
PYH2_k127_10150_5 Endoribonuclease L-PSP - - - 0.0000000000000000001219 93.0
PYH2_k127_10150_6 Protein of unknown function (DUF1385) - - - 0.00000000000001992 75.0
PYH2_k127_10150_7 zinc finger, SWIM - - - 0.000006897 51.0
PYH2_k127_1039840_0 Dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 533.0
PYH2_k127_1039840_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006421 400.0
PYH2_k127_1039840_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.000000000000000000000005895 104.0
PYH2_k127_1039840_3 PFAM peptidase M3A and M3B, thimet oligopeptidase F K08602 - - 0.0000004548 53.0
PYH2_k127_106070_0 COG0665 Glycine D-amino acid oxidases (deaminating) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 313.0
PYH2_k127_106070_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001646 263.0
PYH2_k127_106070_2 Protein of unknown function (DUF1512) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004619 265.0
PYH2_k127_106070_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000001102 255.0
PYH2_k127_106070_4 Belongs to the arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000001924 138.0
PYH2_k127_106070_5 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000002895 119.0
PYH2_k127_106070_6 Universal stress protein family - - - 0.00000000000000002935 88.0
PYH2_k127_106070_7 - - - - 0.000003394 49.0
PYH2_k127_106070_8 metalloendopeptidase activity - - - 0.0006044 48.0
PYH2_k127_1086229_0 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006942 316.0
PYH2_k127_1086229_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001142 233.0
PYH2_k127_1086229_2 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000001495 199.0
PYH2_k127_1086229_3 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000000000000005482 181.0
PYH2_k127_1086229_4 FtsX-like permease family - - - 0.000000000000000000000000001985 119.0
PYH2_k127_1086229_5 FtsX-like permease family - - - 0.0000000000000000004417 103.0
PYH2_k127_1086229_6 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000005165 74.0
PYH2_k127_1114250_0 DNA polymerase K02319 - 2.7.7.7 2.368e-242 775.0
PYH2_k127_1114250_1 Belongs to the arginase family K01480 - 3.5.3.11 0.000000000000000000000000000000000000000000000000000001003 203.0
PYH2_k127_1123248_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000001255 253.0
PYH2_k127_1123248_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000001543 234.0
PYH2_k127_1123248_2 - - - - 0.00000000000000000000000000000000000000000000000004585 187.0
PYH2_k127_1123248_3 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000002884 180.0
PYH2_k127_1123248_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.0000000000000002701 89.0
PYH2_k127_1123248_5 PFAM AMP-dependent synthetase and ligase - - - 0.00000001076 67.0
PYH2_k127_1137137_0 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 564.0
PYH2_k127_1137137_1 peptidase M42 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001912 261.0
PYH2_k127_1137137_2 Aminoacyl-tRNA editing domain - - - 0.0000000000000000000000000000000000000001629 154.0
PYH2_k127_1137137_3 - - - - 0.00000000000000000000000000001527 128.0
PYH2_k127_1167751_0 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000003425 185.0
PYH2_k127_1167751_1 QueT transporter - - - 0.00000000003584 70.0
PYH2_k127_1167751_2 Protein of unknown function (DUF998) - - - 0.0000000002363 68.0
PYH2_k127_1167751_3 TIGRFAM histidinol phosphate phosphatase HisJ family K04486 - 3.1.3.15 0.00008172 47.0
PYH2_k127_118034_0 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 392.0
PYH2_k127_118034_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 298.0
PYH2_k127_118034_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000001093 176.0
PYH2_k127_118034_3 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.00000000000000000000000000000000000003266 149.0
PYH2_k127_118034_4 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000001285 143.0
PYH2_k127_118034_5 PFAM molybdopterin biosynthesis MoaE K03635,K21142 - 2.8.1.12 0.000000000007308 68.0
PYH2_k127_118034_6 PBP superfamily domain K05772 - - 0.0000000001631 65.0
PYH2_k127_1221938_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 519.0
PYH2_k127_1221938_1 Conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000000000000008395 173.0
PYH2_k127_1221938_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000005771 135.0
PYH2_k127_122931_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 393.0
PYH2_k127_122931_1 PFAM inner-membrane translocator K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004282 329.0
PYH2_k127_122931_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001494 258.0
PYH2_k127_122931_3 PFAM inner-membrane translocator K01997 - - 0.00000000000000000000000000000000000000000000000000000001607 209.0
PYH2_k127_122931_4 beta-lactamase - - - 0.0000000000000000000001796 102.0
PYH2_k127_122931_5 branched-chain amino acid transport K01996 - - 0.000001166 50.0
PYH2_k127_1230824_0 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000000000000000000000000000000000000000000000000000000000000000000004898 241.0
PYH2_k127_1230824_1 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.00000000000000000000000000000000000000000000000000000000009441 211.0
PYH2_k127_1230824_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000002068 68.0
PYH2_k127_1249017_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008819 389.0
PYH2_k127_1249017_1 4Fe-4S single cluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 348.0
PYH2_k127_1262821_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000002297 241.0
PYH2_k127_1262821_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000002307 241.0
PYH2_k127_1262821_2 Predicted membrane protein (DUF2318) - - - 0.0000000000000001358 87.0
PYH2_k127_1262821_3 Class III cytochrome C family - - - 0.00003106 49.0
PYH2_k127_1286047_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 340.0
PYH2_k127_1286047_2 - - - - 0.00000000000000000000000000000000000000001719 165.0
PYH2_k127_1286047_3 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000003841 134.0
PYH2_k127_1286047_4 MFS_1 like family - - - 0.0000001177 61.0
PYH2_k127_1292470_0 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000001658 139.0
PYH2_k127_1292470_1 membrane-associated protein domain - - - 0.0000000000000000000000000003326 128.0
PYH2_k127_1292470_2 Belongs to the thioredoxin family K03671 - - 0.0000009226 53.0
PYH2_k127_1312690_0 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 469.0
PYH2_k127_1312690_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 304.0
PYH2_k127_1312690_2 phosphatase activity K07025,K08723 - 3.1.3.5 0.0000000000000000000168 93.0
PYH2_k127_1385691_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 538.0
PYH2_k127_1385691_1 Domain of unknown function (DUF4438) - - - 0.00000000002416 67.0
PYH2_k127_1405036_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009224 287.0
PYH2_k127_1405036_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000005013 184.0
PYH2_k127_1405036_2 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000008874 138.0
PYH2_k127_1405036_3 biosynthesis methyltransferase - - - 0.00000003469 55.0
PYH2_k127_1405036_4 - - - - 0.0001499 45.0
PYH2_k127_1406275_0 Belongs to the peptidase S16 family - - - 1.075e-227 721.0
PYH2_k127_1406275_1 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000003405 183.0
PYH2_k127_1419112_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 376.0
PYH2_k127_1436160_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009354 462.0
PYH2_k127_1436160_1 Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000001621 269.0
PYH2_k127_1442526_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 561.0
PYH2_k127_1442526_1 regulatory protein, arsR - - - 0.0003196 46.0
PYH2_k127_1497016_0 inositol 2-dehydrogenase activity - - - 0.00000000000000000000003295 104.0
PYH2_k127_1497016_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000001037 105.0
PYH2_k127_1497016_2 Putative zinc- or iron-chelating domain K06940 - - 0.0000001142 59.0
PYH2_k127_150947_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 311.0
PYH2_k127_150947_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000001643 211.0
PYH2_k127_150947_2 zinc finger - - - 0.000000000000000000000000000000000000003349 156.0
PYH2_k127_150947_3 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.00000000000000000000000000000000000002341 149.0
PYH2_k127_150947_4 Belongs to the thioredoxin family K03671 - - 0.000000000173 66.0
PYH2_k127_150947_5 - - - - 0.00001864 51.0
PYH2_k127_156364_0 enzyme of poly-gamma-glutamate biosynthesis (Capsule formation) K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005678 261.0
PYH2_k127_156364_1 PFAM peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000007203 233.0
PYH2_k127_156364_2 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000007882 177.0
PYH2_k127_1576695_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 299.0
PYH2_k127_1576695_1 ATP-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000005257 218.0
PYH2_k127_1581976_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 1.712e-204 649.0
PYH2_k127_1581976_1 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 2.022e-202 643.0
PYH2_k127_1581976_2 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 428.0
PYH2_k127_1581976_3 Alanyl-tRNA synthetase K01872 GO:0002161,GO:0003674,GO:0003824,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 6.1.1.7 0.0000000000000000000000000000000000000000000000002531 180.0
PYH2_k127_1581976_4 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.0000000002981 70.0
PYH2_k127_167090_0 aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 453.0
PYH2_k127_167090_1 ACT domain protein - - - 0.00000000000148 73.0
PYH2_k127_168121_0 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000000000000000000000003795 194.0
PYH2_k127_168121_1 - - - - 0.0000000000000000000000000000000000000002937 163.0
PYH2_k127_1699582_0 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 515.0
PYH2_k127_1699582_1 PFAM peptidyl-prolyl cis-trans isomerase cyclophilin type K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000006045 181.0
PYH2_k127_1699582_2 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.0000000000005491 74.0
PYH2_k127_177673_0 SMART KH domain protein K07041 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 526.0
PYH2_k127_177673_1 PFAM PUA domain containing protein K07575 - - 0.000000000000000000000004983 107.0
PYH2_k127_177673_2 Pfam:DUF552 K09152 - - 0.000000000000008662 78.0
PYH2_k127_1797856_0 Sugar fermentation stimulation protein K06206 - - 0.000000000000000000000000000000000000000000000004029 178.0
PYH2_k127_1797856_1 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000005278 143.0
PYH2_k127_1797856_2 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.00000000000439 76.0
PYH2_k127_1800907_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 338.0
PYH2_k127_1800907_1 - - - - 0.0000000000000000000000000000000000000000000000000001191 194.0
PYH2_k127_1800907_2 PFAM methyltransferase small - - - 0.00000000000000000000000000000000000000000000009133 175.0
PYH2_k127_1800907_3 PFAM CRS1 YhbY (CRM) domain K07574 - - 0.000000000000000002046 87.0
PYH2_k127_1800907_4 ASNC family K03718 - - 0.00000000000006696 77.0
PYH2_k127_1800907_5 DNA-binding transcription factor activity - - - 0.000000000000411 79.0
PYH2_k127_1800907_6 Transcriptional regulator K03718 - - 0.00000000004339 70.0
PYH2_k127_1800907_7 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000001392 72.0
PYH2_k127_1800907_8 PFAM Glycosyl transferase family 2 - - - 0.0000003193 56.0
PYH2_k127_1800907_9 COG3634 Alkyl hydroperoxide reductase, large subunit K00384 - 1.8.1.9 0.0001212 48.0
PYH2_k127_1804532_0 TIGRFAM formate dehydrogenase, alpha subunit K00336,K05299 - 1.17.1.10,1.6.5.3 1.142e-246 781.0
PYH2_k127_1804532_1 PFAM Phosphoribosylglycinamide synthetase K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 360.0
PYH2_k127_1804532_2 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007729 327.0
PYH2_k127_1804532_3 - - - - 0.000000000000000000000000000000000000000000000000000004735 197.0
PYH2_k127_1804532_4 Aminotransferase - - - 0.0000000000000000000000000000000000000001344 165.0
PYH2_k127_1804532_5 excinuclease ABC, C subunit - - - 0.00000000000000000000000000000000008806 138.0
PYH2_k127_1804532_6 segregation and condensation protein K06024 - - 0.0000000000000000000000008586 111.0
PYH2_k127_1804532_7 membrane protein domain - - - 0.000000000000000000000004096 109.0
PYH2_k127_1804532_8 Hydrolase - - - 0.0000000000000001733 88.0
PYH2_k127_1804532_9 Desulfoferrodoxin ferrous iron-binding K05919 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016721,GO:0019430,GO:0022900,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.2 0.000000002705 58.0
PYH2_k127_1827998_0 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 374.0
PYH2_k127_1827998_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001329 239.0
PYH2_k127_1827998_2 Aminotransferase K00812,K10907,K14155 - 2.6.1.1,4.4.1.8 0.000000000000000000000000000000000000000000000000000000005071 213.0
PYH2_k127_1827998_3 UbiA prenyltransferase family K20616 - - 0.00000000000000000000000000000000776 138.0
PYH2_k127_1827998_4 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000005836 88.0
PYH2_k127_1827998_5 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000004283 54.0
PYH2_k127_1838020_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 622.0
PYH2_k127_1838020_1 PFAM regulatory protein AsnC Lrp family - - - 0.000001234 53.0
PYH2_k127_1838020_2 PFAM regulatory protein AsnC Lrp family - - - 0.000002617 53.0
PYH2_k127_1843545_0 Ferredoxin K00335,K05587,K17992,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 278.0
PYH2_k127_1843545_1 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000000003309 192.0
PYH2_k127_1843545_2 2 iron, 2 sulfur cluster binding K00334 - 1.6.5.3 0.0000000000000000000000000000000000000008462 153.0
PYH2_k127_1845681_0 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000006938 111.0
PYH2_k127_1845681_1 Glycosyltransferase like family 2 - - - 0.000000002916 68.0
PYH2_k127_1845681_2 TIGRFAM anion transporter K03319,K11106 - - 0.00001596 55.0
PYH2_k127_1860494_0 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000002709 198.0
PYH2_k127_1860494_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000002892 175.0
PYH2_k127_1860494_2 Transcription elongation factor Spt5 K02601 - - 0.000000000000000000000000000000000000000306 153.0
PYH2_k127_1860494_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000003761 55.0
PYH2_k127_1881366_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000004102 214.0
PYH2_k127_1881366_1 Peptidase family M28 K01438 - 3.5.1.16 0.0000000000000000000000000002157 122.0
PYH2_k127_1881366_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000004112 91.0
PYH2_k127_1893348_0 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007439 524.0
PYH2_k127_1893348_1 TSCPD domain - - - 0.000000000000000000000000001316 114.0
PYH2_k127_1893348_2 - - - - 0.00000005372 65.0
PYH2_k127_1896808_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 2.611e-223 716.0
PYH2_k127_1896808_1 ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 519.0
PYH2_k127_1896808_10 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000005662 77.0
PYH2_k127_1896808_11 pyridoxamine 5-phosphate - - - 0.00004089 51.0
PYH2_k127_1896808_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00005604 53.0
PYH2_k127_1896808_13 ATP synthase subunit C K02124 - - 0.0005638 48.0
PYH2_k127_1896808_2 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 453.0
PYH2_k127_1896808_3 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 439.0
PYH2_k127_1896808_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 417.0
PYH2_k127_1896808_5 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007942 285.0
PYH2_k127_1896808_6 Zn-dependent protease with chaperone function K03799 - - 0.00000000000000000000000000000000000000000000000000000000003769 218.0
PYH2_k127_1896808_7 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000009121 189.0
PYH2_k127_1896808_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.00000000000000000000000000000008739 127.0
PYH2_k127_1896808_9 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.00000000000000000000000373 108.0
PYH2_k127_1924175_0 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 464.0
PYH2_k127_19324_0 Flavodoxin - GO:0000166,GO:0003674,GO:0003824,GO:0004729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0010181,GO:0016491,GO:0016627,GO:0016634,GO:0016635,GO:0018130,GO:0019438,GO:0032553,GO:0033013,GO:0033014,GO:0034641,GO:0036094,GO:0042168,GO:0042440,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055114,GO:0070818,GO:0070819,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000001226 210.0
PYH2_k127_19324_1 CAAX protease self-immunity K07052 - - 0.00000000000000000000008196 108.0
PYH2_k127_19324_2 - - - - 0.0004395 45.0
PYH2_k127_1943843_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 343.0
PYH2_k127_1943843_1 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000003956 189.0
PYH2_k127_1943843_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000008407 151.0
PYH2_k127_195237_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 9.758e-214 680.0
PYH2_k127_195237_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001181 285.0
PYH2_k127_195237_2 DEAD DEAH box helicase domain protein K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000001394 239.0
PYH2_k127_195237_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000009809 200.0
PYH2_k127_1963838_0 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000002188 134.0
PYH2_k127_1963838_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000006889 81.0
PYH2_k127_1963838_3 response to antibiotic - - - 0.00001457 51.0
PYH2_k127_197602_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005996 355.0
PYH2_k127_197602_1 Cys/Met metabolism PLP-dependent enzyme K01556,K01620 - 3.7.1.3,4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 325.0
PYH2_k127_197602_2 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001348 252.0
PYH2_k127_197602_3 Belongs to the serpin family K13963 - - 0.00000000000000000000000000000000000000000000000005205 186.0
PYH2_k127_197602_4 PFAM CBS domain containing protein - - - 0.00000000004162 69.0
PYH2_k127_197602_5 - - - - 0.00000000004386 70.0
PYH2_k127_197602_6 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.000003812 51.0
PYH2_k127_1983762_0 PFAM metal-dependent phosphohydrolase, HD sub domain K06951 - - 0.00000000000000000000000000000000000000000000000002668 184.0
PYH2_k127_1983762_1 thiolester hydrolase activity K06889 - - 0.00000000001438 77.0
PYH2_k127_1998032_0 Amidinotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 548.0
PYH2_k127_1998032_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005795 286.0
PYH2_k127_1998032_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000005437 196.0
PYH2_k127_1998032_3 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000005406 147.0
PYH2_k127_1998032_4 membrane - - - 0.000000000000000000000005395 109.0
PYH2_k127_1998032_5 - - - - 0.00000005178 57.0
PYH2_k127_1998032_6 - - - - 0.000001071 58.0
PYH2_k127_2013251_0 PFAM Beta propeller domain K14475 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 437.0
PYH2_k127_2031876_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0034220,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044464,GO:0044769,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0099131,GO:0099132,GO:1902600 3.6.3.14,3.6.3.15 6.455e-197 630.0
PYH2_k127_2031876_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003491 592.0
PYH2_k127_2031876_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000001396 102.0
PYH2_k127_2031876_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000001765 61.0
PYH2_k127_2031876_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0001326 51.0
PYH2_k127_204581_0 Peptidase family S58 K01266 - 3.4.11.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 300.0
PYH2_k127_204581_1 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 295.0
PYH2_k127_204581_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000643 285.0
PYH2_k127_204581_3 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001833 289.0
PYH2_k127_204581_4 Protein of unknown function (DUF917) K09703 - - 0.000000000000000001179 89.0
PYH2_k127_204581_5 PFAM Putitive phosphate transport regulator K07220 - - 0.000000000000002344 84.0
PYH2_k127_2060476_0 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 314.0
PYH2_k127_2060476_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000002775 176.0
PYH2_k127_2065954_0 Zinc carboxypeptidase K14054 - - 7.44e-210 675.0
PYH2_k127_2065954_1 Belongs to the peptidase M24B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 399.0
PYH2_k127_2065954_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000002195 149.0
PYH2_k127_2065954_3 PFAM glutaredoxin - - - 0.000000000000000000007153 94.0
PYH2_k127_2077124_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 383.0
PYH2_k127_2077124_1 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.0000000000000000000000000000000000000009819 153.0
PYH2_k127_2077124_2 Fe-S-cluster oxidoreductase K06940 - - 0.00000000000000000000000009866 113.0
PYH2_k127_2077124_3 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000004773 59.0
PYH2_k127_2114726_0 Oligopeptidase F K08602 - - 1.498e-224 711.0
PYH2_k127_2114726_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000001665 244.0
PYH2_k127_2114726_2 Pyridoxamine 5-phosphate K07005 - - 0.0000000000000000000000000196 114.0
PYH2_k127_2114726_3 CBS domain - - - 0.0000000000000000001971 93.0
PYH2_k127_2114726_4 Mediates influx of magnesium ions K03284 - - 0.000005413 55.0
PYH2_k127_2140536_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007593 304.0
PYH2_k127_2140536_1 PFAM LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000004562 221.0
PYH2_k127_2140536_2 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000004643 224.0
PYH2_k127_2140536_3 Psort location Cytoplasmic, score K01262 - 3.4.11.9 0.000000000000000000000000000000000000000006344 169.0
PYH2_k127_2140536_4 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0001281 53.0
PYH2_k127_2149473_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 331.0
PYH2_k127_2149473_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000008781 242.0
PYH2_k127_2153022_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 297.0
PYH2_k127_2153022_1 Structural maintenance of chromosomes - GO:0000003,GO:0000228,GO:0000280,GO:0000706,GO:0000722,GO:0000723,GO:0000724,GO:0000725,GO:0000729,GO:0000781,GO:0000793,GO:0000794,GO:0000803,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007063,GO:0007088,GO:0007127,GO:0007131,GO:0007346,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009410,GO:0009987,GO:0010033,GO:0010243,GO:0010564,GO:0010638,GO:0010705,GO:0014070,GO:0014074,GO:0016043,GO:0016462,GO:0016604,GO:0016605,GO:0016607,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0022414,GO:0030054,GO:0030915,GO:0031000,GO:0031974,GO:0031981,GO:0032200,GO:0032502,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0033554,GO:0034091,GO:0034093,GO:0034182,GO:0034184,GO:0034641,GO:0035061,GO:0035825,GO:0035861,GO:0036270,GO:0042221,GO:0042493,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043279,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044464,GO:0045787,GO:0045840,GO:0045876,GO:0045931,GO:0046483,GO:0048285,GO:0048518,GO:0048522,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051276,GO:0051321,GO:0051716,GO:0051726,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0060249,GO:0061982,GO:0062033,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:0071840,GO:0090068,GO:0090304,GO:0090398,GO:0090734,GO:0097159,GO:0098687,GO:0106068,GO:0140013,GO:1901360,GO:1901363,GO:1901698,GO:1902494,GO:1903046,GO:1990234,GO:2001252 - 0.0000000000000004459 93.0
PYH2_k127_2153022_2 Structural maintenance of chromosomes protein - GO:0000793,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0030915,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0106068,GO:1901360,GO:1902494,GO:1990234 - 0.000000000000001791 91.0
PYH2_k127_2153022_3 transferase activity, transferring glycosyl groups - - - 0.00000000002586 73.0
PYH2_k127_2166585_0 FAD binding domain K00239,K18209 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0022900,GO:0044237,GO:0045333,GO:0055114 1.3.4.1,1.3.5.1,1.3.5.4 1.611e-208 662.0
PYH2_k127_2166585_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 616.0
PYH2_k127_2166585_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 536.0
PYH2_k127_2166585_3 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 292.0
PYH2_k127_2166585_4 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002809 282.0
PYH2_k127_2166585_5 Fumarate hydratase K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000848 264.0
PYH2_k127_2166585_6 Fe-S type, tartrate fumarate subfamily, beta K01678,K03780 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000007292 236.0
PYH2_k127_2166585_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000004942 141.0
PYH2_k127_2170143_0 Flavodoxin - - - 0.0000000000000000000000000000000000000641 147.0
PYH2_k127_2170143_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000001671 157.0
PYH2_k127_2170143_2 Major facilitator superfamily K08223 - - 0.0000000000003872 81.0
PYH2_k127_2170143_3 Serine (or cysteine) peptidase inhibitor, clade F, member 1 K19614 GO:0003008,GO:0003674,GO:0004857,GO:0004866,GO:0004867,GO:0005575,GO:0005576,GO:0005604,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0007275,GO:0007399,GO:0007610,GO:0007611,GO:0007613,GO:0007614,GO:0008150,GO:0008283,GO:0008285,GO:0009892,GO:0009987,GO:0010466,GO:0010468,GO:0010594,GO:0010596,GO:0010605,GO:0010629,GO:0010632,GO:0010633,GO:0010720,GO:0010941,GO:0010951,GO:0010975,GO:0010976,GO:0016525,GO:0019222,GO:0022008,GO:0022603,GO:0030154,GO:0030162,GO:0030234,GO:0030334,GO:0030336,GO:0030414,GO:0030424,GO:0031012,GO:0031323,GO:0031324,GO:0031344,GO:0031346,GO:0031347,GO:0031348,GO:0032101,GO:0032102,GO:0032268,GO:0032269,GO:0032501,GO:0032502,GO:0032879,GO:0033267,GO:0036477,GO:0040012,GO:0040013,GO:0042127,GO:0042995,GO:0043005,GO:0043025,GO:0043086,GO:0043203,GO:0044092,GO:0044297,GO:0044421,GO:0044424,GO:0044444,GO:0044463,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045765,GO:0045861,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048585,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050678,GO:0050680,GO:0050727,GO:0050728,GO:0050767,GO:0050769,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0051093,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051172,GO:0051239,GO:0051240,GO:0051241,GO:0051246,GO:0051248,GO:0051270,GO:0051271,GO:0051336,GO:0051346,GO:0051960,GO:0051962,GO:0052547,GO:0052548,GO:0060255,GO:0060284,GO:0060548,GO:0060768,GO:0060770,GO:0061134,GO:0061135,GO:0062023,GO:0065007,GO:0065009,GO:0080090,GO:0080134,GO:0097458,GO:0098772,GO:0120025,GO:0120035,GO:0120038,GO:1901214,GO:1901215,GO:1901342,GO:1901343,GO:2000026,GO:2000145,GO:2000146,GO:2000181,GO:2000241,GO:2000242 - 0.00003657 46.0
PYH2_k127_2185371_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000001987 212.0
PYH2_k127_2185371_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000002953 201.0
PYH2_k127_2185371_2 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000005726 147.0
PYH2_k127_2227313_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004492 376.0
PYH2_k127_2227313_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000001566 182.0
PYH2_k127_2227313_2 HpcH/HpaI aldolase/citrate lyase family - - - 0.0000000000000000000000000000000000000412 153.0
PYH2_k127_2227313_3 Protein of unknown function (DUF998) - - - 0.00000000000000000000008234 106.0
PYH2_k127_2247748_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008728 270.0
PYH2_k127_2247748_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000007417 231.0
PYH2_k127_2277281_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 5.702e-285 902.0
PYH2_k127_2288340_0 proline dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006305 456.0
PYH2_k127_2288340_1 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000005419 265.0
PYH2_k127_2288340_2 PFAM regulatory protein AsnC Lrp family K03718 - - 0.0000000000000000000000000000000000000008973 152.0
PYH2_k127_2288340_3 Transcriptional regulator - - - 0.000000000000000000000006653 108.0
PYH2_k127_23567_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 6.618e-194 614.0
PYH2_k127_23567_1 Gamma-glutamyltranspeptidase 2-like K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 573.0
PYH2_k127_23567_2 Peptidase, S9A B C family, catalytic domain protein K01303 - 3.4.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 387.0
PYH2_k127_2370568_0 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000002109 231.0
PYH2_k127_2370568_1 PFAM peptidyl-prolyl cis-trans isomerase cyclophilin type K03767 - 5.2.1.8 0.00000000000005779 75.0
PYH2_k127_2370568_2 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000006466 52.0
PYH2_k127_2380862_0 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004862 312.0
PYH2_k127_2380862_1 ribonuclease activity K07060 - - 0.000000000000000002002 89.0
PYH2_k127_2380862_2 ABC-2 family transporter protein K01992 - - 0.000000000000001621 81.0
PYH2_k127_2386030_0 Zinc carboxypeptidase K14054 - - 1.201e-245 784.0
PYH2_k127_2386030_1 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000000000000000000000002521 254.0
PYH2_k127_2386030_2 Aminotransferase K00812,K10907,K14155 - 2.6.1.1,4.4.1.8 0.00000000000000000000000000000000000000000000000000000008748 210.0
PYH2_k127_2386030_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000001582 164.0
PYH2_k127_2386030_4 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000001819 166.0
PYH2_k127_2386030_5 peptide deformylase activity K01462 - 3.5.1.88 0.000000000000000000000000003849 117.0
PYH2_k127_2386030_6 TIGRFAM TIGR04076 family protein - - - 0.0000000000000000004316 90.0
PYH2_k127_2386030_7 Beta-lactamase class C and other penicillin binding - - - 0.000000001595 63.0
PYH2_k127_2386030_8 Major facilitator superfamily - - - 0.00000134 55.0
PYH2_k127_2386030_9 - - - - 0.000006082 55.0
PYH2_k127_2399069_0 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 406.0
PYH2_k127_2399069_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000006053 118.0
PYH2_k127_2399069_2 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000309 100.0
PYH2_k127_2412312_0 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 383.0
PYH2_k127_2412312_1 Diphthamide K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000002393 238.0
PYH2_k127_2412312_10 Belongs to the UPF0215 family K09120 - - 0.000000002169 64.0
PYH2_k127_2412312_11 PFAM RNA polymerase Rpb4 K03051 - 2.7.7.6 0.000009213 52.0
PYH2_k127_2412312_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000001092 209.0
PYH2_k127_2412312_3 Protein of unknown function (DUF655) K07572 - - 0.000000000000000000000000000000000000000000000000003422 187.0
PYH2_k127_2412312_4 Belongs to the universal ribosomal protein uL16 family K02866 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001545 153.0
PYH2_k127_2412312_5 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000000000001879 123.0
PYH2_k127_2412312_6 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.00000000000000000000000002025 118.0
PYH2_k127_2412312_7 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000404 106.0
PYH2_k127_2412312_8 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000007484 94.0
PYH2_k127_2412312_9 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.000000000002088 70.0
PYH2_k127_2417598_0 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 410.0
PYH2_k127_2417598_1 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 375.0
PYH2_k127_2427176_0 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 448.0
PYH2_k127_2427176_1 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000002586 163.0
PYH2_k127_2427176_2 sister chromatid segregation - - - 0.00000000000234 69.0
PYH2_k127_2434579_0 Acyl-CoA synthetase (NDP forming) K01905,K18594,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000003263 250.0
PYH2_k127_2434579_1 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000002899 136.0
PYH2_k127_2434579_2 Catalyzes the release of L-lysine from LysW -gamma-L- lysine and the release of L-ornithine from LysW -L-ornithine K05831 - - 0.00000000000000000000000000201 117.0
PYH2_k127_2447060_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000802 387.0
PYH2_k127_2447060_1 - - - - 0.0000000000000000000000000000000000000001008 154.0
PYH2_k127_2447060_2 TIGRFAM archaeal flagellin N-terminal-like domain - - - 0.000000000000000003097 90.0
PYH2_k127_2447060_3 protein conserved in archaea - - - 0.0009359 48.0
PYH2_k127_2466484_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000106 64.0
PYH2_k127_2476660_0 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 313.0
PYH2_k127_2476660_1 conserved protein implicated in secretion - - - 0.0000000000000000000000000000000000000000000000008034 181.0
PYH2_k127_2476660_2 conserved protein implicated in secretion - - - 0.0000000000000001995 89.0
PYH2_k127_2484485_0 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 291.0
PYH2_k127_2484485_1 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000002615 243.0
PYH2_k127_2484485_2 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000003962 175.0
PYH2_k127_2484485_3 regulatory protein, arsR - - - 0.0000000000008078 72.0
PYH2_k127_2484485_4 Methyltransferase type 11 K06983 - - 0.00000006238 55.0
PYH2_k127_24966_0 cobalamin transport - - - 0.000000000000000000000000000000000000000000000000000000000000000004134 237.0
PYH2_k127_24966_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000005068 184.0
PYH2_k127_24966_2 PAAR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000002106 176.0
PYH2_k127_24966_3 Phage baseplate assembly protein W K06903 - - 0.000000000000000000000000000000000001782 142.0
PYH2_k127_24966_4 Baseplate J family protein - - - 0.000000000000000000000000000000366 126.0
PYH2_k127_24966_5 protocatechuate 3,4-dioxygenase - - - 0.00000000000000374 84.0
PYH2_k127_2547718_0 carboxypeptidase activity K12941,K13048 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005118 572.0
PYH2_k127_2547718_1 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000001091 245.0
PYH2_k127_2547718_2 Membrane protein-like protein - - - 0.000000003938 64.0
PYH2_k127_255764_0 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000002334 208.0
PYH2_k127_255764_1 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.000000000000000000000000000000000000000000000002715 181.0
PYH2_k127_255764_2 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000000000007611 119.0
PYH2_k127_255764_3 Domain of unknown function (DUF1805) - - - 0.00000000000000000000006665 100.0
PYH2_k127_255764_4 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000001956 74.0
PYH2_k127_255764_5 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.000000001637 60.0
PYH2_k127_255764_6 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.00000001116 60.0
PYH2_k127_2569631_0 in RNase L inhibitor, RLI K06174 - - 5.937e-198 633.0
PYH2_k127_2569631_1 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000008523 197.0
PYH2_k127_2575250_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 360.0
PYH2_k127_2575250_1 Belongs to the ABC transporter superfamily K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 324.0
PYH2_k127_2575250_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001279 253.0
PYH2_k127_2575250_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components - - - 0.0000000000000000000000000000000000000000000000000000000009125 212.0
PYH2_k127_258399_0 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 302.0
PYH2_k127_258399_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000005499 215.0
PYH2_k127_2592506_0 nitroreductase K10678 - - 0.0000000000000000000002107 107.0
PYH2_k127_2592506_1 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000006516 51.0
PYH2_k127_2592506_2 - K07039,K09858 - - 0.00000731 51.0
PYH2_k127_2598630_0 PFAM ATP-NAD AcoX kinase - - - 0.000000000000000000000000000000000000000000000000000000000002 213.0
PYH2_k127_2598630_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000003258 127.0
PYH2_k127_2598630_2 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000003741 108.0
PYH2_k127_2599529_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000002556 256.0
PYH2_k127_2599529_1 peptidase - - - 0.000000000000000000000000000000000000000006654 160.0
PYH2_k127_2599529_2 membrane protein (DUF2078) K08982 - - 0.000009598 49.0
PYH2_k127_2601529_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000003592 236.0
PYH2_k127_2601529_1 DinB family - - - 0.0000000000000001071 85.0
PYH2_k127_2601529_2 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000002689 82.0
PYH2_k127_2601529_3 TrkA-C domain-containing protein - - - 0.000539 43.0
PYH2_k127_264656_0 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000009899 210.0
PYH2_k127_264656_1 protein conserved in archaea - - - 0.00000000002686 72.0
PYH2_k127_2706070_0 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000005881 148.0
PYH2_k127_2706070_1 Transcriptional regulator - - - 0.0001238 49.0
PYH2_k127_2730446_0 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000001531 128.0
PYH2_k127_2730446_1 copper-translocating P-type ATPase K01533 - 3.6.3.4 0.0000000000000003211 79.0
PYH2_k127_2730446_2 SnoaL-like polyketide cyclase - - - 0.0000000000000007912 82.0
PYH2_k127_2738476_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000006713 227.0
PYH2_k127_2738476_1 - - - - 0.0000000000000000000000000000000000000000000000000000000002437 208.0
PYH2_k127_2738476_2 SpoVT / AbrB like domain - - - 0.0000000134 59.0
PYH2_k127_2738476_3 PIN domain - - - 0.0003245 49.0
PYH2_k127_2753568_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004548 327.0
PYH2_k127_2753568_1 Aminopeptidase - - - 0.00000000000000000000000000000000000000000000001564 185.0
PYH2_k127_2792945_0 MutL protein K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 608.0
PYH2_k127_2811010_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 390.0
PYH2_k127_2811010_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 315.0
PYH2_k127_2811010_2 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000001075 201.0
PYH2_k127_2811010_3 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000001186 104.0
PYH2_k127_2811010_4 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000002155 78.0
PYH2_k127_2811010_5 RNA-binding protein of the translin family K07477 - - 0.000000000005084 68.0
PYH2_k127_2811010_6 - - - - 0.00009713 50.0
PYH2_k127_2833279_0 Molybdopterin oxidoreductase Fe4S4 region K00123,K00367 - 1.17.1.9,1.7.7.2 5.222e-245 773.0
PYH2_k127_2852188_0 - K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000005296 213.0
PYH2_k127_2852188_1 Calcineurin-like phosphoesterase - - - 0.00000000000000002956 95.0
PYH2_k127_2885681_0 ATP dephospho-CoA triphosphoribosyl transferase K05966 - 2.4.2.52 0.0000000000000000000000000000000000000000000000001733 188.0
PYH2_k127_2885681_1 Flavoprotein - - - 0.000000000000000000000000000000000005529 139.0
PYH2_k127_2885681_2 DNA polymerase beta domain protein region K09717 - - 0.0000000000000000000000001049 119.0
PYH2_k127_2885681_3 GHMP kinases N terminal domain - - - 0.0000000000000000000000008046 107.0
PYH2_k127_2885681_4 Protein of unknown function (DUF447) K09154 - - 0.000000001658 67.0
PYH2_k127_290134_0 Acetyltransferase (GNAT) domain - - - 0.000000000000001671 80.0
PYH2_k127_293014_0 Radical SAM domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000005 207.0
PYH2_k127_293014_1 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0000000000000000000000000000000000000000000000001475 194.0
PYH2_k127_293014_2 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000104 124.0
PYH2_k127_293014_3 Stage II sporulation protein M K06384 - - 0.0000000000000118 81.0
PYH2_k127_293014_4 4Fe-4S single cluster domain - - - 0.000000000000678 70.0
PYH2_k127_293014_5 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.00001748 50.0
PYH2_k127_3026250_0 Belongs to the LDH2 MDH2 oxidoreductase family K13574 - - 0.000000000000000000000000000000000000000000000003125 183.0
PYH2_k127_3026250_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000001999 128.0
PYH2_k127_3100904_0 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000001687 196.0
PYH2_k127_3100904_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.0000000000000000000000000000000000000000000000008012 187.0
PYH2_k127_3100904_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000911 168.0
PYH2_k127_3100904_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000003847 160.0
PYH2_k127_3100904_4 Belongs to the eukaryotic ribosomal protein eL18 family K02883 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001247 102.0
PYH2_k127_3100904_5 PFAM regulatory protein AsnC Lrp family - - - 0.00000000000005456 74.0
PYH2_k127_3100904_6 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00001217 53.0
PYH2_k127_3100904_7 Putative adhesin - - - 0.00008556 54.0
PYH2_k127_3125154_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000006943 211.0
PYH2_k127_3125154_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000004534 173.0
PYH2_k127_3125154_2 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.0000000000000000000000000003215 118.0
PYH2_k127_3227185_0 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 406.0
PYH2_k127_3227185_1 - - - - 0.000000000000000000000000000000000000001444 150.0
PYH2_k127_3227185_2 GrpB protein - - - 0.000000000000000000000000000000268 129.0
PYH2_k127_3227185_3 of the drug metabolite transporter (DMT) superfamily - - - 0.0003443 44.0
PYH2_k127_325773_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004 555.0
PYH2_k127_325773_1 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 514.0
PYH2_k127_325773_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000003328 103.0
PYH2_k127_325773_11 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000002343 106.0
PYH2_k127_325773_12 SCP-2 sterol transfer family - - - 0.0000000001135 68.0
PYH2_k127_325773_2 PFAM Aminotransferase class I and II K05825 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 316.0
PYH2_k127_325773_3 CoA binding domain K01905 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 317.0
PYH2_k127_325773_4 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000002376 217.0
PYH2_k127_325773_5 carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000001656 211.0
PYH2_k127_325773_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0006725,GO:0006732,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0042357,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0046483,GO:0046983,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000009387 214.0
PYH2_k127_325773_7 helix_turn_helix ASNC type - - - 0.0000000000000000000000000000000000000000001266 163.0
PYH2_k127_325773_8 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000003671 156.0
PYH2_k127_325773_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000008333 139.0
PYH2_k127_3282045_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004193 414.0
PYH2_k127_3282045_1 TIGRFAM FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000001593 204.0
PYH2_k127_3282045_2 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000001968 158.0
PYH2_k127_3293616_0 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007738 349.0
PYH2_k127_3293616_1 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000004228 142.0
PYH2_k127_3293616_2 Deacylase K15784 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032787,GO:0042399,GO:0042400,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046700,GO:0071704,GO:0072329,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.1.125 0.0000000000000001793 90.0
PYH2_k127_3293616_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000004556 87.0
PYH2_k127_3405136_0 pseudouridine synthase activity K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009239 317.0
PYH2_k127_3405136_1 PP-loop family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006687 253.0
PYH2_k127_3405136_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000003189 201.0
PYH2_k127_3405136_3 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000004696 192.0
PYH2_k127_3405136_4 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.00000000000000000000000000000001658 139.0
PYH2_k127_3405136_5 Protein of unknown function DUF47 K07220 - - 0.00000000000000002212 90.0
PYH2_k127_3405136_6 - - - - 0.0000000005207 63.0
PYH2_k127_3405136_7 MFS_1 like family - - - 0.00001145 57.0
PYH2_k127_3405136_8 ThiS family K03636 - - 0.0006689 46.0
PYH2_k127_3407092_0 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM-like protein - - - 0.00000000000000000000000000000000000000000000000000000003002 207.0
PYH2_k127_3407092_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000003021 180.0
PYH2_k127_3407092_2 Molybdopterin-binding domain of aldehyde dehydrogenase K20448 - 1.17.1.5 0.0000000000000000000000000000000000000000000003279 171.0
PYH2_k127_3407092_3 XdhC Rossmann domain K07402 - - 0.00000000000000000000000000000000000005945 152.0
PYH2_k127_3407092_4 Transcriptional regulator - - - 0.000000000000000007569 83.0
PYH2_k127_3407092_5 Guanylyl transferase CofC like K07141 - 2.7.7.76 0.0000000004959 65.0
PYH2_k127_3411656_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004573 589.0
PYH2_k127_3471012_0 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005127 314.0
PYH2_k127_3471012_1 Predicted membrane protein (DUF2207) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002201 270.0
PYH2_k127_3471012_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000009996 138.0
PYH2_k127_3471012_3 Cupin domain - - - 0.00003329 51.0
PYH2_k127_3471012_4 Major Facilitator Superfamily - - - 0.000589 51.0
PYH2_k127_3497673_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008236 332.0
PYH2_k127_3497673_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000007785 203.0
PYH2_k127_3497673_2 modulator of DNA gyrase K03568 - - 0.000001533 53.0
PYH2_k127_3532106_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000001093 141.0
PYH2_k127_3532106_1 Major Facilitator Superfamily - - - 0.0000000000001825 82.0
PYH2_k127_3532696_0 membrane K07149 - - 0.000000000000000000000000000000000000000000000000000000000001504 216.0
PYH2_k127_3532696_1 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000002451 188.0
PYH2_k127_3532696_2 CoA binding domain K06929 - - 0.0000000000000000000000000005588 116.0
PYH2_k127_3540029_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336,K18332 - 1.12.1.3,1.6.5.3 4.283e-195 623.0
PYH2_k127_3540029_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004125 433.0
PYH2_k127_3540029_2 Fe-S-cluster oxidoreductase K06940 - - 0.0009561 48.0
PYH2_k127_3588871_0 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 447.0
PYH2_k127_3588871_1 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000132 194.0
PYH2_k127_3588871_2 HTH DNA binding domain - - - 0.0002115 47.0
PYH2_k127_3588871_3 Met-10+ like-protein K07055 - 2.5.1.114 0.0004082 44.0
PYH2_k127_3605_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000005583 111.0
PYH2_k127_3605_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000834 81.0
PYH2_k127_3605_2 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000002654 79.0
PYH2_k127_360823_0 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000001741 158.0
PYH2_k127_360823_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.00000000000000000000000000000005696 142.0
PYH2_k127_3661137_0 LOR SDH bifunctional - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 460.0
PYH2_k127_3661137_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000005285 98.0
PYH2_k127_3670445_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000932 251.0
PYH2_k127_3670445_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000006655 110.0
PYH2_k127_3695485_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.179e-234 744.0
PYH2_k127_3695485_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 4.666e-196 628.0
PYH2_k127_3695485_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 508.0
PYH2_k127_3695485_3 Belongs to the eukaryotic ribosomal protein eL15 family K02877 - - 0.0000000000000000000000000000000000000000000000000006917 187.0
PYH2_k127_3695485_4 Zn-dependent hydrolase - - - 0.000000000000000000000000000000000000000001365 164.0
PYH2_k127_3695485_5 Belongs to the UPF0273 family - - - 0.0000000000000000000000000000003397 131.0
PYH2_k127_3695485_6 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000001187 119.0
PYH2_k127_3695485_7 Glycosyl transferase family group 2 - - - 0.000000000000000005395 88.0
PYH2_k127_3695485_8 Fcf1 K07158 - - 0.000000000000000006816 88.0
PYH2_k127_372859_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 464.0
PYH2_k127_372859_1 PFAM D-aminoacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000028 295.0
PYH2_k127_372859_2 PFAM Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000007181 212.0
PYH2_k127_372859_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.00000000000000000000000000000000000000000000000000000000007766 216.0
PYH2_k127_372859_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000222 192.0
PYH2_k127_372859_5 COG1921 Selenocysteine synthase seryl-tRNASer selenium transferase K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000002686 190.0
PYH2_k127_372859_6 - K07092 - - 0.0000000000000000000000000000000000000000000002156 169.0
PYH2_k127_372859_7 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000001914 116.0
PYH2_k127_372859_8 ATPase activity K01990 - - 0.0000000000006201 74.0
PYH2_k127_3738948_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 543.0
PYH2_k127_3738948_1 ABC-2 type transporter K01992 - - 0.000000000000000000000000001101 120.0
PYH2_k127_3779881_0 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000001832 207.0
PYH2_k127_3779881_1 - - - - 0.0000000000000000000000000000000000000000000000003133 187.0
PYH2_k127_3779881_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000007266 178.0
PYH2_k127_3830682_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009173 432.0
PYH2_k127_3830682_1 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 389.0
PYH2_k127_3830682_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000002571 166.0
PYH2_k127_3830682_3 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.00000000000000003386 83.0
PYH2_k127_3830682_4 Bacterial transferase hexapeptide (six repeats) K00638,K00661,K18234 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008374,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044444,GO:0044464 2.3.1.28,2.3.1.79 0.00002848 47.0
PYH2_k127_3871558_0 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005457 248.0
PYH2_k127_3871558_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000004443 104.0
PYH2_k127_3909956_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.00000000000000000000000000000000000000000000000000000000000000000006466 235.0
PYH2_k127_3909956_1 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.0000000000000000000000000000000000000000000000000000000000000002843 227.0
PYH2_k127_3909956_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000002434 202.0
PYH2_k127_3909956_3 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.00000000000000000000000000284 114.0
PYH2_k127_3967394_0 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000001659 199.0
PYH2_k127_3967394_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000409 193.0
PYH2_k127_3967394_2 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000004132 187.0
PYH2_k127_3967394_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000001314 135.0
PYH2_k127_4075519_0 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002912 284.0
PYH2_k127_4075519_1 DNA polymerase beta domain protein region K07073 - - 0.00000000000000000000000000000000000000000000000000000000009831 211.0
PYH2_k127_4075519_2 PFAM peptidase M50 - - - 0.000000000000000000000003747 113.0
PYH2_k127_4075519_3 PFAM SMC domain protein K03546 - - 0.0000000000000000002409 103.0
PYH2_k127_4075519_4 PFAM Metallophosphoesterase K03547 - - 0.0000000000000003275 91.0
PYH2_k127_4075519_5 NurA - - - 0.000003684 59.0
PYH2_k127_4127589_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000003707 246.0
PYH2_k127_4127589_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749,K18702 - 2.8.3.16,2.8.3.19 0.000000000000000000000000000000000000000000000000000000000000000002343 241.0
PYH2_k127_4127589_2 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000002152 122.0
PYH2_k127_4156411_0 PFAM Nickel-dependent hydrogenase, large subunit K14126 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 602.0
PYH2_k127_4156411_1 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 346.0
PYH2_k127_4156411_2 heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000006303 198.0
PYH2_k127_4156411_3 hydrogenase maturation protease K03605 - - 0.00000000000007715 75.0
PYH2_k127_41797_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000008607 154.0
PYH2_k127_41797_1 Putative esterase K07017 - - 0.0000000000000000000000000000003284 131.0
PYH2_k127_41797_2 glycolate biosynthetic process - - - 0.000000000004965 74.0
PYH2_k127_4256609_0 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 - 2.1.1.215,2.1.1.216 0.000000000000000000000000000000000000000000000000000000000000000000000000000002077 277.0
PYH2_k127_4256609_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000001381 99.0
PYH2_k127_4256609_2 Malate/L-lactate dehydrogenase K13574 - - 0.0000004287 53.0
PYH2_k127_4298594_0 - - - - 0.00000000000000000000000000000000000000000000000000000000002232 211.0
PYH2_k127_4298594_1 - - - - 0.000000000000000000000000555 109.0
PYH2_k127_43595_0 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006996 293.0
PYH2_k127_43595_1 electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000123 280.0
PYH2_k127_43595_2 Protein conserved in bacteria - - - 0.0000000000000001447 85.0
PYH2_k127_43595_3 Sulfite exporter TauE/SafE K07090 - - 0.00000007383 58.0
PYH2_k127_438487_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 411.0
PYH2_k127_438487_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000009565 199.0
PYH2_k127_438487_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000001788 189.0
PYH2_k127_438487_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000001034 154.0
PYH2_k127_438487_4 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000003826 71.0
PYH2_k127_439920_0 aconitate hydratase K01681 - 4.2.1.3 3.793e-244 769.0
PYH2_k127_439920_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 446.0
PYH2_k127_439920_2 Zn-dependent hydrolase - - - 0.000005466 51.0
PYH2_k127_4479612_0 hydrogenase expression formation protein K04654 - - 0.0000000000000000000000000000000000000000000000000000000000009856 215.0
PYH2_k127_4479612_1 DHHA2 K15986 - 3.6.1.1 0.0002093 49.0
PYH2_k127_4566177_0 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 414.0
PYH2_k127_4566177_1 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.0000000000000000000000000000000006199 135.0
PYH2_k127_4665589_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000001078 239.0
PYH2_k127_4665589_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000001743 79.0
PYH2_k127_46753_0 PFAM extracellular solute-binding protein family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 391.0
PYH2_k127_46753_1 C-terminal binding-module, SLH-like, of glucodextranase - - - 0.00000000000000000000000008949 120.0
PYH2_k127_4699665_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000006725 114.0
PYH2_k127_4699665_1 RNA binding K07581 - - 0.0000000000006545 75.0
PYH2_k127_4699665_2 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00000000002564 69.0
PYH2_k127_4746102_0 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000003383 140.0
PYH2_k127_4746102_1 carboxylic ester hydrolase activity - - - 0.000000000000000000000000004573 115.0
PYH2_k127_4746102_2 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17105 - 2.5.1.42 0.0000000000000000000000003317 115.0
PYH2_k127_4775925_0 enterobactin catabolic process - - - 1.101e-217 689.0
PYH2_k127_4775925_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 320.0
PYH2_k127_4775925_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000006855 181.0
PYH2_k127_4830327_0 Amidohydrolase family K06015 - 3.5.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001672 293.0
PYH2_k127_4830327_1 TIGRFAM reductive dehalogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005593 246.0
PYH2_k127_4830327_2 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000003401 178.0
PYH2_k127_4944917_0 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000005504 189.0
PYH2_k127_4944917_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000006833 174.0
PYH2_k127_4944917_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000003844 141.0
PYH2_k127_4944917_3 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000001007 137.0
PYH2_k127_4944917_4 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000003979 78.0
PYH2_k127_5006853_0 Radical SAM domain protein K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 307.0
PYH2_k127_5006853_1 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000004206 268.0
PYH2_k127_5006853_2 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.0000000000125 68.0
PYH2_k127_5011961_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002826 306.0
PYH2_k127_5011961_1 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000002902 212.0
PYH2_k127_5011961_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000005564 55.0
PYH2_k127_5103548_0 Amidohydrolase family K01465,K01466 - 3.5.2.3,3.5.2.5 0.00000000000000000000000000000000000000000000000000000000001095 216.0
PYH2_k127_5103548_1 Belongs to the UPF0200 family - - - 0.0000000000000000000000000000000000000000001511 165.0
PYH2_k127_5103548_2 TIGRFAM anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000001016 154.0
PYH2_k127_5103548_3 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000002635 109.0
PYH2_k127_5103548_4 Belongs to the UPF0201 family K09736 - - 0.0000000005706 65.0
PYH2_k127_5112215_0 xylulokinase activity K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 409.0
PYH2_k127_5112215_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 385.0
PYH2_k127_5112215_2 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 306.0
PYH2_k127_5112215_3 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006226 249.0
PYH2_k127_5112215_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000001626 218.0
PYH2_k127_5112215_5 PFAM peptidase M14 carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000003115 181.0
PYH2_k127_5112215_6 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000003567 181.0
PYH2_k127_5112215_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000009939 139.0
PYH2_k127_5112215_8 Transcriptional regulator PadR-like family - - - 0.0000000000000001057 85.0
PYH2_k127_5112215_9 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000003206 72.0
PYH2_k127_518270_0 radical SAM K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 539.0
PYH2_k127_518270_1 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001865 297.0
PYH2_k127_518270_2 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000001815 95.0
PYH2_k127_5183663_0 2-keto-3-deoxy-L-rhamnonate aldolase activity K02510,K12660 - 4.1.2.52,4.1.2.53 0.000000000000000000000000000000000000000000000000001925 190.0
PYH2_k127_5183663_1 signal peptidase complex catalytic subunit K13280 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005787,GO:0005789,GO:0006465,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0012505,GO:0016020,GO:0016485,GO:0016787,GO:0019538,GO:0031090,GO:0031984,GO:0032991,GO:0034641,GO:0042175,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0051604,GO:0071704,GO:0098796,GO:0098827,GO:0140096,GO:1901564,GO:1902494,GO:1905368 3.4.21.89 0.00000000003637 68.0
PYH2_k127_53268_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 339.0
PYH2_k127_53268_1 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000002473 216.0
PYH2_k127_53268_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000005154 163.0
PYH2_k127_53268_3 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.0000000000000000000000000000000000001337 152.0
PYH2_k127_5332271_0 PFAM peptidase M19 renal dipeptidase K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000002178 199.0
PYH2_k127_5332271_1 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0034214,GO:0042802,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0051259,GO:0065003,GO:0071840 - 0.0000000000000000000000000001504 118.0
PYH2_k127_5332271_2 Ribosomal RNA adenine dimethylase - - - 0.00000000000000000000000000138 115.0
PYH2_k127_5332271_3 Major Facilitator Superfamily - - - 0.0000000000002391 82.0
PYH2_k127_5334701_0 PFAM beta-lactamase domain protein K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 336.0
PYH2_k127_5334701_1 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 297.0
PYH2_k127_534311_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008426 346.0
PYH2_k127_534311_1 TIGRFAM geranylgeranyl reductase - - - 0.0000000000000000000000000000000000000000000000002144 191.0
PYH2_k127_534311_2 peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000002758 178.0
PYH2_k127_534311_3 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.0000000000000000000000000005756 117.0
PYH2_k127_534311_4 Domain of unknown function (DUF1610) K07580 - - 0.000000000000000005159 84.0
PYH2_k127_535534_0 DEAD DEAH box helicase domain protein K03724 - - 5.019e-237 760.0
PYH2_k127_535534_1 PFAM GCN5-related N-acetyltransferase K03790 - 2.3.1.128 0.00000000000000000002845 92.0
PYH2_k127_5392858_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 597.0
PYH2_k127_5392858_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003853 582.0
PYH2_k127_5392858_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009453 419.0
PYH2_k127_5392858_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 374.0
PYH2_k127_5392858_4 PFAM molybdopterin binding domain K03742 - 3.5.1.42 0.00000000000000000000000000000000000000000000000000008563 196.0
PYH2_k127_5421590_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 399.0
PYH2_k127_5421590_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 294.0
PYH2_k127_5421590_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000001181 243.0
PYH2_k127_5480312_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000901 579.0
PYH2_k127_5480312_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000387 421.0
PYH2_k127_5480312_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 345.0
PYH2_k127_5480312_3 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001539 286.0
PYH2_k127_5480312_4 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009806 283.0
PYH2_k127_5480312_5 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000006413 158.0
PYH2_k127_5480312_6 Belongs to the NDK family K00940 - 2.7.4.6 0.00000000000000000000000000007104 122.0
PYH2_k127_5480312_7 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000000000001421 104.0
PYH2_k127_5480312_8 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000000003866 87.0
PYH2_k127_55041_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 1.806e-300 958.0
PYH2_k127_55041_1 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 - 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000002615 246.0
PYH2_k127_55041_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.0000000000000000000000000000000000000000000000000000000000000001436 229.0
PYH2_k127_55041_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.00000000000000000000000000000000000000000004803 179.0
PYH2_k127_55041_4 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.000000000000000001737 89.0
PYH2_k127_55041_5 PFAM Transcription elongation factor Elf1 like - - - 0.000000001364 62.0
PYH2_k127_55041_6 Sec61beta family - - - 0.000008338 49.0
PYH2_k127_5559932_0 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 457.0
PYH2_k127_5559932_1 Succinate dehydrogenase fumarate reductase flavoprotein K00394 - 1.8.99.2 0.0000000000000004892 80.0
PYH2_k127_5559932_2 DinB family - - - 0.000228 46.0
PYH2_k127_5565797_0 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000001495 109.0
PYH2_k127_5565797_1 - - - - 0.00000000000000000004282 100.0
PYH2_k127_5565797_2 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000001376 77.0
PYH2_k127_5565797_3 - - - - 0.000004945 53.0
PYH2_k127_5585328_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 402.0
PYH2_k127_5585328_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 337.0
PYH2_k127_5585328_2 DNA primase K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 320.0
PYH2_k127_5611344_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K16792 - 4.2.1.114 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 407.0
PYH2_k127_5611344_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 300.0
PYH2_k127_5611344_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000001115 178.0
PYH2_k127_5611344_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0002798 43.0
PYH2_k127_565853_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007037 368.0
PYH2_k127_565853_1 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000002229 237.0
PYH2_k127_565853_2 PFAM CBS domain containing protein - - - 0.0000000000000000001495 93.0
PYH2_k127_565853_3 FAD dependent oxidoreductase - - - 0.0000000004683 62.0
PYH2_k127_565853_4 TM2 domain - - - 0.000000004419 62.0
PYH2_k127_5678569_0 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 362.0
PYH2_k127_5678569_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005196 287.0
PYH2_k127_5678569_2 Fe-S-cluster oxidoreductase K06940 - - 0.0000001033 61.0
PYH2_k127_5700114_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 444.0
PYH2_k127_5700114_1 Putative esterase K07017 - - 0.000000000000000000000000000000000009024 145.0
PYH2_k127_575297_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 441.0
PYH2_k127_5787342_0 Domain of unknown function (DUF4438) - - - 0.00000000000000000000000000000000000000000000000000000000000000001172 234.0
PYH2_k127_5787342_1 Domain of unknown function (DUF4438) - - - 0.00000000000000000000000000000000000000000001342 168.0
PYH2_k127_5787342_2 Catalyzes the cleavage of the N-glycosidic bond of deoxyribonucleoside 5'-monophosphates to yield deoxyribose 5- phosphate and a purine or pyrimidine base - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.00000000000000000000000000191 116.0
PYH2_k127_5787342_3 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000001299 111.0
PYH2_k127_5787342_4 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.000000000000000000293 92.0
PYH2_k127_5787342_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000003479 67.0
PYH2_k127_579051_0 GMP synthase, glutamine-hydrolyzing K01951 GO:0000162,GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042401,GO:0042430,GO:0042435,GO:0042451,GO:0042455,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046129,GO:0046219,GO:0046390,GO:0046394,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901657,GO:1901659,GO:1902494 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 302.0
PYH2_k127_579051_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004627 300.0
PYH2_k127_5802419_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 2.052e-225 713.0
PYH2_k127_5802419_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 328.0
PYH2_k127_5802419_2 May be involved in maturation of the 30S ribosomal subunit K02966 - - 0.000000000000000000000000000000000000000000000002528 177.0
PYH2_k127_5802419_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000002741 96.0
PYH2_k127_5802419_4 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000001321 89.0
PYH2_k127_5802419_5 Belongs to the ribosomal protein L31e family K02910 - - 0.00000000000000116 79.0
PYH2_k127_5802419_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.00000000007717 63.0
PYH2_k127_5802419_7 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000001263 66.0
PYH2_k127_5802419_8 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000003772 53.0
PYH2_k127_5802419_9 PFAM Ribosomal L18ae LX protein domain K02944 - - 0.000003691 51.0
PYH2_k127_5814848_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 462.0
PYH2_k127_5814848_1 Transcriptional regulator - - - 0.0000000000000000000000000000000002203 138.0
PYH2_k127_5822267_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001359 265.0
PYH2_k127_5822267_1 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000003847 158.0
PYH2_k127_5822267_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000002298 94.0
PYH2_k127_5912766_0 Phenazine biosynthesis-like protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 310.0
PYH2_k127_5912766_1 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 300.0
PYH2_k127_5912766_10 DGC domain - - - 0.0000000000000003111 81.0
PYH2_k127_5912766_11 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000001459 64.0
PYH2_k127_5912766_12 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0002177 51.0
PYH2_k127_5912766_2 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000002238 238.0
PYH2_k127_5912766_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00000000000000000000000000000000000000000008788 165.0
PYH2_k127_5912766_4 OsmC-like protein - - - 0.0000000000000000000000000000000000003639 144.0
PYH2_k127_5912766_5 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000002233 138.0
PYH2_k127_5912766_6 Bacterial PH domain - - - 0.0000000000000000000000000009139 119.0
PYH2_k127_5912766_7 DGC domain - - - 0.0000000000000000000000000405 112.0
PYH2_k127_5912766_8 Transcriptional regulator - - - 0.00000000000000000000000982 104.0
PYH2_k127_5912766_9 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000001605 109.0
PYH2_k127_5940241_0 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 327.0
PYH2_k127_5940241_1 PFAM Thiamine pyrophosphate K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000009327 266.0
PYH2_k127_5940241_2 Domain of unknown function (DUF2437) - - - 0.000000000000000000000000000000000000000000000000000000000000000002259 239.0
PYH2_k127_5940241_3 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000147 191.0
PYH2_k127_5940241_4 Putative RNA methyltransferase K09142 - - 0.00000000000000000000000000000000000000000000000002718 189.0
PYH2_k127_5940241_5 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000001678 131.0
PYH2_k127_5940241_6 - - - - 0.00000000000000000000000000001916 122.0
PYH2_k127_5940241_7 - - - - 0.00000000000000000000002323 105.0
PYH2_k127_5940241_8 oxidoreductase subunit delta K00171 - 1.2.7.1 0.0000000000000000000009833 96.0
PYH2_k127_5940241_9 PFAM ROK family protein K00845 - 2.7.1.2 0.0000000000000003361 81.0
PYH2_k127_5941973_0 PFAM peptidase S58 DmpA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 307.0
PYH2_k127_5941973_1 O-methyltransferase - - - 0.0000000000000000000000000003639 120.0
PYH2_k127_5941973_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000008083 63.0
PYH2_k127_6007424_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 2.056e-228 739.0
PYH2_k127_6007424_1 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 605.0
PYH2_k127_6007424_10 acetolactate synthase, small K01653 - 2.2.1.6 0.000000000000000000000000000000000000003694 152.0
PYH2_k127_6007424_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 561.0
PYH2_k127_6007424_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 404.0
PYH2_k127_6007424_4 Pantothenate synthetase K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008498 297.0
PYH2_k127_6007424_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000004323 262.0
PYH2_k127_6007424_6 PFAM Aminotransferase class I and II K14155 - 4.4.1.8 0.000000000000000000000000000000000000000000000000002583 196.0
PYH2_k127_6007424_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000001984 188.0
PYH2_k127_6007424_8 kinase, sugar kinase superfamily K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000000005773 181.0
PYH2_k127_6007424_9 Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.0000000000000000000000000000000000000009615 153.0
PYH2_k127_606740_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 490.0
PYH2_k127_606740_1 DegT/DnrJ/EryC1/StrS aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000002563 130.0
PYH2_k127_6101333_0 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 556.0
PYH2_k127_6101333_1 CorA-like Mg2+ transporter protein K03284 GO:0000041,GO:0000287,GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006824,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015087,GO:0015095,GO:0015318,GO:0015693,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0022857,GO:0022890,GO:0030001,GO:0031224,GO:0031226,GO:0034220,GO:0042802,GO:0043167,GO:0043169,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046873,GO:0046914,GO:0046915,GO:0050897,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0055085,GO:0065003,GO:0070838,GO:0071840,GO:0071944,GO:0072511,GO:0098655,GO:0098660,GO:0098662,GO:1903830 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 368.0
PYH2_k127_6101333_2 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.0000000000000000000000000000000000000004194 159.0
PYH2_k127_6101333_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 - 2.7.7.2 0.000000000000000000000000004346 115.0
PYH2_k127_6101333_4 diphthine synthase K20215 - 2.1.1.98 0.000000000000003727 79.0
PYH2_k127_6102220_0 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000008622 160.0
PYH2_k127_6102220_1 PFAM Ribulose-phosphate 3-epimerase K01783 - 5.1.3.1 0.000000000000000000000000000000478 130.0
PYH2_k127_6181280_0 Domain of unknown function (DUF4438) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002773 260.0
PYH2_k127_6181280_1 Conserved protein implicated in secretion - - - 0.00000000000000000000000313 107.0
PYH2_k127_6183459_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 415.0
PYH2_k127_6183459_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000008832 166.0
PYH2_k127_6215597_0 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 300.0
PYH2_k127_6215597_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000002635 254.0
PYH2_k127_6215597_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000001106 173.0
PYH2_k127_6215597_3 homoserine dehydrogenase K00003 - 1.1.1.3 0.00005449 52.0
PYH2_k127_6220383_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 336.0
PYH2_k127_6220383_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.000000000000000000000000000000000000000000000000000007145 196.0
PYH2_k127_6220383_2 Beta-Casp domain K07041 - - 0.0000000000000000000000000000000003027 136.0
PYH2_k127_6226695_0 TIGRFAM thioredoxin K03671 - - 0.0000000000000000000000000000009528 124.0
PYH2_k127_6226695_1 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000004593 118.0
PYH2_k127_6226695_2 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000002599 75.0
PYH2_k127_6226695_3 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000008617 57.0
PYH2_k127_6234617_0 Sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001707 269.0
PYH2_k127_6234617_1 dna ligase K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000008685 193.0
PYH2_k127_6234617_2 - - - - 0.000000000000000000000000000000000000000000001538 174.0
PYH2_k127_6234617_3 PFAM ATP-NAD AcoX kinase - - - 0.00000000000000000000000000000000000000000001959 166.0
PYH2_k127_6234617_4 Mechanosensitive ion channel K16052 - - 0.00000000000006905 81.0
PYH2_k127_6251292_0 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007731 268.0
PYH2_k127_6251292_1 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000009192 228.0
PYH2_k127_6251292_2 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000249 150.0
PYH2_k127_6251292_3 carboxylic ester hydrolase activity - - - 0.00003142 55.0
PYH2_k127_6277863_0 Transcriptional regulator K07729 - - 0.0000000000000002121 80.0
PYH2_k127_6277863_1 - - - - 0.000000000001033 71.0
PYH2_k127_6277863_2 Sugar (and other) transporter - - - 0.000000000001063 79.0
PYH2_k127_6300283_0 MiaB-like tRNA modifying enzyme K15865 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 359.0
PYH2_k127_6300283_1 Serine aminopeptidase, S33 - - - 0.000000000000000009271 93.0
PYH2_k127_6300283_2 SAM-dependent methyltransferase K06968 - 2.1.1.186 0.00000000000000006444 85.0
PYH2_k127_6300283_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000005393 67.0
PYH2_k127_6408111_0 PFAM Cytochrome c assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000003001 200.0
PYH2_k127_6408111_1 ABC-type transport system involved in cytochrome c biogenesis permease component K02195 - - 0.00000000000000000000000000000000000000000000009322 176.0
PYH2_k127_6408111_2 ABC transporter K02193 - 3.6.3.41 0.000000000000000000000000000000000000000002063 163.0
PYH2_k127_6408111_3 ABC-type transport system involved in cytochrome c biogenesis permease component K02194 - - 0.0000000000000001243 89.0
PYH2_k127_6408111_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000002904 67.0
PYH2_k127_6516183_0 Phosphotriesterase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 350.0
PYH2_k127_6516183_1 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000003021 268.0
PYH2_k127_6516183_2 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000638 155.0
PYH2_k127_6530469_0 Conserved protein implicated in secretion - - - 0.000000000000000000000000000000000005372 144.0
PYH2_k127_6530469_1 Trypsin - - - 0.00000000000000000000000000000004938 132.0
PYH2_k127_6530469_2 Transcriptional regulator K07332 - - 0.000000000000000000002655 101.0
PYH2_k127_6530469_3 Conserved protein implicated in secretion - - - 0.00000000001389 74.0
PYH2_k127_6546273_0 carboxypeptidase activity K12941,K13048 - - 9.564e-199 630.0
PYH2_k127_6546273_1 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000003388 208.0
PYH2_k127_6547636_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0 1202.0
PYH2_k127_6556913_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1061.0
PYH2_k127_6556913_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 548.0
PYH2_k127_6556913_2 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000002613 203.0
PYH2_k127_6556913_3 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000003861 51.0
PYH2_k127_6561973_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 536.0
PYH2_k127_6561973_1 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000007736 54.0
PYH2_k127_6578331_0 Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily K05829 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 410.0
PYH2_k127_6578331_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K05830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 357.0
PYH2_k127_6578331_2 Involved in both the arginine and lysine biosynthetic pathways. Phosphorylates the LysW-bound precursors glutamate (for arginine biosynthesis), respectively alpha-aminoadipate (for lysine biosynthesis) K05828 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001436 262.0
PYH2_k127_6587629_0 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.000000000000000000000000000000001783 130.0
PYH2_k127_6587841_0 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 340.0
PYH2_k127_6587841_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 295.0
PYH2_k127_6587841_2 PHP domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003539 284.0
PYH2_k127_6587841_3 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000001142 65.0
PYH2_k127_6593044_0 helicase superfamily c-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 398.0
PYH2_k127_6593044_1 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K18105 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003376 285.0
PYH2_k127_6593044_2 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000002767 211.0
PYH2_k127_6593044_3 B3/4 domain - - - 0.00000000000000000000000000000000000000000000000000000003463 203.0
PYH2_k127_6593044_4 COG1056 Nicotinamide mononucleotide adenylyltransferase K00952 - 2.7.7.1 0.000000000000000000000001328 106.0
PYH2_k127_6593044_5 Protein of unknown function (DUF790) K09744 - - 0.0000000000001482 82.0
PYH2_k127_661086_0 COG1032 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005111 529.0
PYH2_k127_6625462_0 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 300.0
PYH2_k127_6625462_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000393 164.0
PYH2_k127_6625462_2 ferredoxin oxidoreductase K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.00000000000000000000000000002074 133.0
PYH2_k127_6627183_0 ABC-type cobalt transport system ATPase component K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 295.0
PYH2_k127_6627183_1 Phosphate uptake regulator - - - 0.0000000000000000000000000000000000001252 149.0
PYH2_k127_6627183_2 PFAM Cobalt transport protein K16785 - - 0.000000000000000000000000000000001465 139.0
PYH2_k127_6667371_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001717 200.0
PYH2_k127_6667371_1 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.00000000000000000000000000000339 130.0
PYH2_k127_6667371_2 binds to the 23S rRNA K02929 - - 0.0000000000000000000000000157 111.0
PYH2_k127_6667371_3 PFAM ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001395 78.0
PYH2_k127_6667371_4 protein conserved in archaea K09723 - - 0.00000002218 63.0
PYH2_k127_6674878_0 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 308.0
PYH2_k127_6674878_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002557 288.0
PYH2_k127_6674878_2 Conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000000000000002757 177.0
PYH2_k127_6674878_3 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000003042 76.0
PYH2_k127_6674878_4 Dolichol kinase - - - 0.000000005027 64.0
PYH2_k127_6690194_0 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000294 202.0
PYH2_k127_6690194_1 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000001085 159.0
PYH2_k127_6690194_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000008817 89.0
PYH2_k127_6690194_3 - - - - 0.00000000000131 75.0
PYH2_k127_6690194_4 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000003659 68.0
PYH2_k127_6697227_0 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003786 322.0
PYH2_k127_6697227_1 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002219 242.0
PYH2_k127_6697227_2 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.00000000000000000000000000000000000429 144.0
PYH2_k127_6707392_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 346.0
PYH2_k127_6707392_1 Imidazole acetol-phosphate transaminase K00817 - 2.6.1.9 0.00000000000000000002168 97.0
PYH2_k127_6707936_0 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 327.0
PYH2_k127_6707936_1 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000008071 132.0
PYH2_k127_6707936_2 Alkyl hydroperoxide reductase K03564 - 1.11.1.15 0.0000000000000000001235 89.0
PYH2_k127_6707936_3 Transporter, major facilitator family protein K08223 - - 0.0000000000001099 82.0
PYH2_k127_6707936_4 M42 glutamyl aminopeptidase K01179 - 3.2.1.4 0.0000000001528 64.0
PYH2_k127_6708648_0 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000003936 237.0
PYH2_k127_6721419_0 Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT( ) K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000001636 249.0
PYH2_k127_6721419_1 PFAM PUA domain containing protein K07398 - - 0.0000000000000000000000000000000001958 137.0
PYH2_k127_6721419_2 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000004539 129.0
PYH2_k127_6721419_3 Transcriptional regulator, XRE family K03627 - - 0.00000000000000000000002317 107.0
PYH2_k127_6721419_4 - - - - 0.000228 46.0
PYH2_k127_6727632_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002097 256.0
PYH2_k127_6727632_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000006961 134.0
PYH2_k127_6776332_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000457 352.0
PYH2_k127_6776332_1 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009252 326.0
PYH2_k127_6776332_2 Necessary for normal cell division and for the maintenance of normal septation - - - 0.0000000000000000000000000001236 123.0
PYH2_k127_6832859_0 N-acetyl-alpha-D-glucosaminyl L-malate synthase K00754 GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 321.0
PYH2_k127_6832859_1 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 304.0
PYH2_k127_6832859_2 Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH K22136 - - 0.000000000001862 80.0
PYH2_k127_6832859_3 GlcNAc-PI de-N-acetylase - - - 0.0000005604 58.0
PYH2_k127_6832957_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000621 602.0
PYH2_k127_6832957_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000001244 228.0
PYH2_k127_6832957_2 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000401 68.0
PYH2_k127_6846603_0 MutL protein - - - 4.896e-198 634.0
PYH2_k127_6846603_1 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000173 303.0
PYH2_k127_6846603_2 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000007231 111.0
PYH2_k127_6846603_3 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000317 81.0
PYH2_k127_6846603_4 Evidence 5 No homology to any previously reported sequences - - - 0.000000000003117 76.0
PYH2_k127_6846603_5 - - - - 0.000005398 56.0
PYH2_k127_6846603_6 - - - - 0.0001516 48.0
PYH2_k127_6847571_0 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001204 280.0
PYH2_k127_6847571_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000001186 136.0
PYH2_k127_6860792_0 Zinc carboxypeptidase K14054 - - 5.038e-240 767.0
PYH2_k127_6860792_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 1.517e-238 749.0
PYH2_k127_6860792_2 MutL protein K00854 - 2.7.1.17 5.433e-213 677.0
PYH2_k127_6860792_3 amidohydrolase K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008847 529.0
PYH2_k127_6860792_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 346.0
PYH2_k127_6860792_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000002892 164.0
PYH2_k127_6860792_6 - - - - 0.0000000000000000000000000000000000000001963 160.0
PYH2_k127_6860792_7 helix_turn_helix, Arsenical Resistance Operon Repressor K22043 - - 0.00000000004234 68.0
PYH2_k127_6860792_8 Transcriptional regulator - - - 0.0000004147 56.0
PYH2_k127_6862360_0 Zinc carboxypeptidase K14054 - - 1.133e-248 792.0
PYH2_k127_6862360_1 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001895 253.0
PYH2_k127_6866078_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 464.0
PYH2_k127_6866078_1 CBS domain K08221 - - 0.0000000000000000002646 91.0
PYH2_k127_6866078_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000001733 78.0
PYH2_k127_6869796_0 GH3 auxin-responsive promoter - - - 0.0000000003418 72.0
PYH2_k127_6869796_1 COG2223 Nitrate nitrite transporter K02575 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000006735 53.0
PYH2_k127_6905835_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 550.0
PYH2_k127_6905835_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 391.0
PYH2_k127_6905835_2 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001346 293.0
PYH2_k127_6905835_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002036 274.0
PYH2_k127_6905835_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000001134 74.0
PYH2_k127_6918693_0 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000001443 226.0
PYH2_k127_6918693_1 - - - - 0.00000000000000000000000000000961 123.0
PYH2_k127_6918693_2 Flavin reductase like domain - - - 0.000000000000000000000007601 104.0
PYH2_k127_6918693_3 PFAM NifU-like domain - - - 0.00000000000000000000006187 100.0
PYH2_k127_6918693_4 - - - - 0.00000000000000007349 86.0
PYH2_k127_6918693_5 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000001973 79.0
PYH2_k127_6941116_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009848 273.0
PYH2_k127_6941116_1 Major facilitator superfamily - - - 0.0000000000000000000001684 109.0
PYH2_k127_6945677_0 ABC transporter, ATP-binding protein K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000001134 235.0
PYH2_k127_6945677_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000002159 185.0
PYH2_k127_6945677_2 Transport permease protein K01992 - - 0.000000000001072 79.0
PYH2_k127_6949537_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 441.0
PYH2_k127_6949537_1 Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues K01299 - 3.4.17.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 402.0
PYH2_k127_6949537_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 337.0
PYH2_k127_6949537_3 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001156 280.0
PYH2_k127_6949537_4 Belongs to the HMG-CoA reductase family K00021,K00054 - 1.1.1.34,1.1.1.88 0.00000000000000000000000000000000000000000000000000000000000000000002048 238.0
PYH2_k127_6949537_5 phosphatase activity K07025,K08723,K20862 - 3.1.3.102,3.1.3.104,3.1.3.5 0.0000000000000000000000000000323 127.0
PYH2_k127_6957467_0 peptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007361 380.0
PYH2_k127_6957467_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000001051 232.0
PYH2_k127_6957468_0 Protein of unknown function (DUF763) K09003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 379.0
PYH2_k127_6957468_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001268 274.0
PYH2_k127_6957468_2 Removes 5-oxoproline from various penultimate amino acid residues except L-proline K01304 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:1901564 3.4.19.3 0.00000000000000000000000000000000000000000000000000005704 193.0
PYH2_k127_6957468_3 Putative TM nitroreductase - - - 0.000000000000000000000000000000000000000000000000101 182.0
PYH2_k127_6957468_4 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.000000000000000000000000000000001134 135.0
PYH2_k127_6957468_5 transglutaminase domain protein - - - 0.00000000000000000000002063 113.0
PYH2_k127_6957468_6 metal ion transport K03319,K14445 - - 0.0000000000000000001685 96.0
PYH2_k127_6957468_7 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0008282 42.0
PYH2_k127_6960205_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 357.0
PYH2_k127_6960205_1 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001688 243.0
PYH2_k127_6960205_2 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000000000000000001725 134.0
PYH2_k127_6984476_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 612.0
PYH2_k127_6984476_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000004411 227.0
PYH2_k127_6984476_2 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000004377 180.0
PYH2_k127_6984476_3 Methyl-viologen-reducing hydrogenase, delta subunit K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000005598 92.0
PYH2_k127_6998093_0 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000006494 153.0
PYH2_k127_6998093_1 Glycosyl transferase 4-like K00754 - - 0.0000000000000000000000000002614 128.0
PYH2_k127_6998093_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000001055 76.0
PYH2_k127_6998208_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 463.0
PYH2_k127_6998208_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000003794 118.0
PYH2_k127_7007318_0 membrane - - - 0.0000000000000000000000000000006404 135.0
PYH2_k127_7007318_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000001008 122.0
PYH2_k127_7007318_2 Thermophilic metalloprotease (M29) - - - 0.00000001079 66.0
PYH2_k127_7041729_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005972 429.0
PYH2_k127_7041729_1 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 327.0
PYH2_k127_7041729_2 ATP-grasp domain K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000009016 269.0
PYH2_k127_7041729_3 Peptidase family S51 - - - 0.0000000000000000000002271 106.0
PYH2_k127_7041729_4 Capsular polysaccharide biosynthesis protein CapK - - - 0.00000000001092 75.0
PYH2_k127_7041729_6 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000001822 63.0
PYH2_k127_7041729_7 polysaccharide lyase family 8 domain protein K01727 GO:0005575,GO:0005576 4.2.2.1 0.0002536 55.0
PYH2_k127_7117549_0 Baseplate J family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 301.0
PYH2_k127_7117549_1 - - - - 0.000000000000000000000000000000000000000000000000000000291 205.0
PYH2_k127_7117549_2 - - - - 0.00000000000000000000000000000000000000000000000000001396 195.0
PYH2_k127_7133714_0 Zinc carboxypeptidase K14054 - - 0.0 1049.0
PYH2_k127_7133714_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000000000000000000000000001518 202.0
PYH2_k127_7139395_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 527.0
PYH2_k127_7139395_1 Periplasmic Protein - - - 0.00000000000000000000000000007695 121.0
PYH2_k127_7144214_0 peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001012 291.0
PYH2_k127_7160039_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 375.0
PYH2_k127_7160039_1 PFAM Glycosyl transferase family 4 K01001 - 2.7.8.15 0.000000000000000000000000000000000000000000000000003627 195.0
PYH2_k127_7160039_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000007974 59.0
PYH2_k127_7160039_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.00001383 49.0
PYH2_k127_7172996_0 CO dehydrogenase flavoprotein domain protein K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000006314 229.0
PYH2_k127_7172996_1 COGs COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - - 0.0000000000000000000000000000000000000000000000000000000006181 205.0
PYH2_k127_7172996_2 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000002217 199.0
PYH2_k127_7172996_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.000002443 50.0
PYH2_k127_7175041_0 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002789 267.0
PYH2_k127_7175041_1 ATP binding protein K06883 - - 0.000000000000000000000000000000000000000000000000000001598 200.0
PYH2_k127_7175041_2 myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.0000000000000000000000000000000000000001313 156.0
PYH2_k127_7175041_3 PFAM CBS domain containing protein - - - 0.000000006053 64.0
PYH2_k127_7177046_0 COG0145 N-methylhydantoinase A acetone carboxylase beta subunit K01469,K01473 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0017168,GO:0034641,GO:0043603,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071704,GO:1901564 3.5.2.14,3.5.2.9 2.775e-197 636.0
PYH2_k127_7177046_1 Belongs to the proline racemase family K01777 - 5.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 308.0
PYH2_k127_7177046_2 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K19244 GO:0000166,GO:0000286,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006522,GO:0006807,GO:0008150,GO:0008152,GO:0009078,GO:0009987,GO:0016491,GO:0016638,GO:0019752,GO:0036094,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046983,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901564,GO:1901605 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 303.0
PYH2_k127_7177046_3 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.00000000000000000000000000000000000000000000000000000000000002728 228.0
PYH2_k127_7177046_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000003421 203.0
PYH2_k127_7177046_5 NUDIX domain - - - 0.000000000000000000000000000000000006218 141.0
PYH2_k127_7177046_6 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000111 143.0
PYH2_k127_7182617_0 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000001314 229.0
PYH2_k127_7182617_1 PAC2 family K07159 - - 0.0000000000000000000001302 107.0
PYH2_k127_7182617_2 Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA K04482 GO:0000003,GO:0000150,GO:0000217,GO:0000228,GO:0000280,GO:0000400,GO:0000709,GO:0000722,GO:0000723,GO:0000724,GO:0000725,GO:0000730,GO:0000793,GO:0000794,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007049,GO:0007127,GO:0007131,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0022414,GO:0022607,GO:0030491,GO:0031974,GO:0031981,GO:0032200,GO:0033554,GO:0034622,GO:0034641,GO:0035825,GO:0042148,GO:0042592,GO:0042623,GO:0042802,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045003,GO:0046483,GO:0048285,GO:0050896,GO:0051276,GO:0051321,GO:0051716,GO:0060249,GO:0061982,GO:0065003,GO:0065004,GO:0065007,GO:0065008,GO:0070013,GO:0070192,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140013,GO:0140097,GO:1901360,GO:1901363,GO:1903046 - 0.000000000018 65.0
PYH2_k127_719784_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006841 473.0
PYH2_k127_719784_1 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 319.0
PYH2_k127_719784_2 PFAM Nickel-dependent hydrogenase, large subunit K00436,K14126,K17993 - 1.12.1.2,1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 321.0
PYH2_k127_719784_3 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000001535 246.0
PYH2_k127_719784_4 Asparaginase K13051 - 3.4.19.5 0.0000000000000000000000000000000000000000000000000000009237 200.0
PYH2_k127_719784_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000002111 175.0
PYH2_k127_719784_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000002252 147.0
PYH2_k127_719784_7 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000001014 103.0
PYH2_k127_719784_8 HupF/HypC family K04653 - - 0.00000000000000000005438 91.0
PYH2_k127_7221852_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 295.0
PYH2_k127_7221852_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665,K06883 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001005 276.0
PYH2_k127_7221852_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000007236 132.0
PYH2_k127_7221852_11 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001437 105.0
PYH2_k127_7221852_12 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000008855 103.0
PYH2_k127_7221852_13 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000006833 62.0
PYH2_k127_7221852_14 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.000000309 55.0
PYH2_k127_7221852_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001947 263.0
PYH2_k127_7221852_3 50S ribosomal protein L4 K02930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009875 250.0
PYH2_k127_7221852_4 Belongs to the eukaryotic ribosomal protein eS4 family K02987 - - 0.000000000000000000000000000000000000000000000000000001659 199.0
PYH2_k127_7221852_5 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000003555 193.0
PYH2_k127_7221852_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000002251 169.0
PYH2_k127_7221852_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000002187 165.0
PYH2_k127_7221852_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000007706 157.0
PYH2_k127_7221852_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000001659 152.0
PYH2_k127_7237630_0 ferredoxin oxidoreductase K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008672 306.0
PYH2_k127_7237630_1 PFAM Thiamine pyrophosphate enzyme, C-terminal K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000427 283.0
PYH2_k127_7237630_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000001357 207.0
PYH2_k127_7240312_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K18020 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0043546,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363 1.2.5.3,1.2.99.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004778 513.0
PYH2_k127_7240312_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 410.0
PYH2_k127_7240312_2 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000007644 144.0
PYH2_k127_7284563_0 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 354.0
PYH2_k127_7284563_1 Proteasome endopeptidase complex K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000003036 204.0
PYH2_k127_7284563_2 Psort location Cytoplasmic, score - - - 0.00000000000000000000000000000000000000000008252 165.0
PYH2_k127_7284563_3 Putative TM nitroreductase - - - 0.0000000000000000000000000000000001252 138.0
PYH2_k127_7284563_4 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.0000000000000000000000311 101.0
PYH2_k127_7284563_5 Aspartyl protease K06985 - - 0.00008576 51.0
PYH2_k127_730483_0 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 474.0
PYH2_k127_730483_1 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 323.0
PYH2_k127_730483_2 molybdopterin binding domain - - - 0.0000000000000000000000000000001672 134.0
PYH2_k127_730483_3 amine dehydrogenase activity - - - 0.00000000000000000000000000007546 127.0
PYH2_k127_730483_4 Rubrerythrin - - - 0.000000000000006363 81.0
PYH2_k127_730483_5 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000002647 64.0
PYH2_k127_7309856_0 Major Facilitator Superfamily K08151 - - 0.0000000122 66.0
PYH2_k127_7309856_1 PFAM PEGA domain - - - 0.00001885 53.0
PYH2_k127_7320171_0 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008966 352.0
PYH2_k127_7320171_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000009787 225.0
PYH2_k127_7320171_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 GO:0003674,GO:0003824,GO:0003861,GO:0016829,GO:0016835,GO:0016836 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000001157 201.0
PYH2_k127_7320171_3 Acetyltransferase (GNAT) domain - - - 0.0005682 49.0
PYH2_k127_7324618_0 phosphohydrolase K09163 - - 0.00000000000000000000000000000000000000000000000000000000000000000001935 241.0
PYH2_k127_7324618_1 M42 glutamyl aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002652 244.0
PYH2_k127_7324618_2 - - - - 0.0000000000000000000000003577 107.0
PYH2_k127_7324618_3 PFAM Peptidase family M28 - - - 0.000001105 51.0
PYH2_k127_7327564_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 6.787e-227 716.0
PYH2_k127_7327564_1 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 384.0
PYH2_k127_7327564_2 - K02339 - 2.7.7.7 0.00000000000000000003414 99.0
PYH2_k127_7327564_3 snRNP Sm proteins K04796 - - 0.00000000000000000004951 91.0
PYH2_k127_7327564_4 Binds to the 23S rRNA K02922 - - 0.0000000000003019 70.0
PYH2_k127_7335205_1 Peptidase M15A K03791 - - 0.000000000000000000000000000001313 123.0
PYH2_k127_7335205_2 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.0000000000000006574 85.0
PYH2_k127_7386608_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001977 201.0
PYH2_k127_7386608_1 selenocysteine lyase - - - 0.000000000000000000000000000000000000003476 155.0
PYH2_k127_7386608_2 GNAT acetyltransferase - - - 0.000000000000000000000000000000000004099 148.0
PYH2_k127_7386608_3 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000006819 96.0
PYH2_k127_7399035_0 Belongs to the universal stress protein A family - - - 0.000000000000003364 81.0
PYH2_k127_7399035_1 Beta-lactamase - - - 0.000000002863 61.0
PYH2_k127_7399035_2 Winged helix-turn-helix - - - 0.00000009573 56.0
PYH2_k127_7408401_0 Pilus assembly protein PilX K02673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 480.0
PYH2_k127_7408401_1 Pilus assembly protein PilX K02673 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 382.0
PYH2_k127_7408401_2 antisigma factor binding K04749,K20978 - - 0.000000000000000795 87.0
PYH2_k127_743982_1 aminopeptidase activity - - - 0.000001758 59.0
PYH2_k127_743982_2 amino acid - GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.0001409 46.0
PYH2_k127_752869_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 311.0
PYH2_k127_752869_1 Staygreen protein K22013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647 4.99.1.10 0.0000000000000000000000000000000006016 134.0
PYH2_k127_752869_2 Metal-sensitive transcriptional repressor K21600 - - 0.0000000000000000000001753 99.0
PYH2_k127_7553380_0 ABC-Type Dipeptide Transport System Periplasmic Component K02035,K13889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 337.0
PYH2_k127_7553380_1 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000005264 136.0
PYH2_k127_7553380_2 PFAM Rieske 2Fe-2S domain K05710 - - 0.0000000000000000000000001737 108.0
PYH2_k127_7579821_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 424.0
PYH2_k127_7579821_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000005641 266.0
PYH2_k127_7579821_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000007549 200.0
PYH2_k127_7579821_3 PFAM Chorismate mutase K04093 GO:0003674,GO:0003824,GO:0004664,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0042802,GO:0042803,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046983,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 5.4.99.5 0.0001746 48.0
PYH2_k127_7637888_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 295.0
PYH2_k127_7637888_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000007639 192.0
PYH2_k127_7637888_2 transporter K07238 - - 0.000000000000000000000000000000000000000000007227 172.0
PYH2_k127_7637888_3 Beta-lactamase superfamily domain K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000212 164.0
PYH2_k127_7722967_0 carboxypeptidase activity K12941,K13048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 475.0
PYH2_k127_7722967_1 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000005774 163.0
PYH2_k127_7756130_0 Belongs to the MCM family K10726 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 330.0
PYH2_k127_7756130_1 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000000000004171 171.0
PYH2_k127_7756130_2 S-methyl-5-thioribose-1-phosphate isomerase activity K00899,K03239,K08963 GO:0000096,GO:0000097,GO:0000166,GO:0000302,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0003824,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005851,GO:0005911,GO:0006082,GO:0006412,GO:0006413,GO:0006518,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0006950,GO:0006979,GO:0008135,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009059,GO:0009066,GO:0009067,GO:0009086,GO:0009506,GO:0009719,GO:0009723,GO:0009725,GO:0009987,GO:0010033,GO:0010035,GO:0010038,GO:0010039,GO:0010467,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017076,GO:0017144,GO:0019001,GO:0019509,GO:0019538,GO:0019752,GO:0030054,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0032870,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0034641,GO:0034645,GO:0035639,GO:0035690,GO:0036094,GO:0042221,GO:0042493,GO:0043043,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046523,GO:0050896,GO:0051716,GO:0055044,GO:0070887,GO:0071241,GO:0071248,GO:0071265,GO:0071267,GO:0071281,GO:0071310,GO:0071369,GO:0071495,GO:0071704,GO:0071731,GO:0071732,GO:0097159,GO:0097366,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.1.100,5.3.1.23 0.00000000000000000001393 97.0
PYH2_k127_7756130_3 GINS complex protein K09723 - - 0.00000001063 63.0
PYH2_k127_781060_0 - - - - 0.00000000000000001207 86.0
PYH2_k127_787730_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009332 477.0
PYH2_k127_787730_1 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002192 273.0
PYH2_k127_787730_2 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000001156 184.0
PYH2_k127_787730_3 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000004797 171.0
PYH2_k127_787730_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000009498 116.0
PYH2_k127_787730_5 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.0000417 51.0
PYH2_k127_7889037_0 GTPase of K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 435.0
PYH2_k127_7889037_1 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 408.0
PYH2_k127_7889037_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005219 324.0
PYH2_k127_7889037_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 298.0
PYH2_k127_7889037_4 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000005214 220.0
PYH2_k127_7889037_5 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000003922 193.0
PYH2_k127_7889037_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000001962 84.0
PYH2_k127_7889037_7 Uncharacterized protein conserved in archaea (DUF2095) - - - 0.000000000000007521 79.0
PYH2_k127_7889037_8 - - - - 0.00001004 51.0
PYH2_k127_7889037_9 N-terminal domain of galactosyltransferase - - - 0.0004003 48.0
PYH2_k127_789459_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 593.0
PYH2_k127_789459_1 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 383.0
PYH2_k127_789459_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 364.0
PYH2_k127_789459_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 337.0
PYH2_k127_789459_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 299.0
PYH2_k127_789459_5 - - - - 0.00000000000000000000000000000000000006012 154.0
PYH2_k127_789459_6 NUDIX domain - - - 0.0000000000000000000001456 104.0
PYH2_k127_789459_7 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.0000000000000002225 80.0
PYH2_k127_789459_8 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000005478 61.0
PYH2_k127_7970926_0 Alpha/beta hydrolase family K08680 - 4.2.99.20 0.000000000000000000000009764 109.0
PYH2_k127_7970926_1 Arginine deiminase K01478 - 3.5.3.6 0.0000000000000000002214 102.0
PYH2_k127_7970926_2 peptidase K01303 - 3.4.19.1 0.00000000000001438 79.0
PYH2_k127_7972791_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1065.0
PYH2_k127_8091045_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002136 265.0
PYH2_k127_8091045_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000131 167.0
PYH2_k127_809950_0 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 400.0
PYH2_k127_809950_1 COGs COG3842 ABC-type spermidine putrescine transport systems ATPase components - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 344.0
PYH2_k127_8151502_0 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000003674 238.0
PYH2_k127_8151502_1 PFAM ABC transporter related K01995 - - 0.0000000000000000000000002977 107.0
PYH2_k127_8151502_2 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000008555 107.0
PYH2_k127_8151502_3 - - - - 0.00000000000002277 80.0
PYH2_k127_8151502_4 - - - - 0.0000006247 53.0
PYH2_k127_817254_0 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.00000000000000000000000000000000000000000000000000006342 190.0
PYH2_k127_817254_1 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.0000000000000000000000000000001436 128.0
PYH2_k127_817254_2 HerA-ATP synthase, barrel domain K06915 - - 0.000000000000001136 90.0
PYH2_k127_8175271_0 COG1363 Cellulase M and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000009693 235.0
PYH2_k127_8175271_1 Beta-lactamase enzyme family K17836 - 3.5.2.6 0.0000000000000000000000000000485 127.0
PYH2_k127_8175271_2 DHHA1 domain K07463 - - 0.000000000000000000000000472 116.0
PYH2_k127_8176954_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K14086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 488.0
PYH2_k127_8176954_1 PFAM NADH-ubiquinone oxidoreductase chain 49kDa K00333,K14090 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 407.0
PYH2_k127_8176954_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 343.0
PYH2_k127_8176954_3 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K03885,K17870 - 1.6.3.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003168 290.0
PYH2_k127_8176954_4 respiratory-chain NADH dehydrogenase subunit 1 K00337,K14087 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000009928 264.0
PYH2_k127_8176954_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002295 246.0
PYH2_k127_8176954_6 4Fe-4S binding domain K14091 - - 0.000000000000000000000002495 105.0
PYH2_k127_8176954_7 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00001992 49.0
PYH2_k127_81811_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 593.0
PYH2_k127_81811_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 470.0
PYH2_k127_81811_10 Integral membrane protein DUF106 - - - 0.0000000005923 67.0
PYH2_k127_81811_11 COG0477 Permeases of the major facilitator superfamily K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000001873 66.0
PYH2_k127_81811_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 428.0
PYH2_k127_81811_3 PFAM D-aminoacylase K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000003484 245.0
PYH2_k127_81811_4 nudix family K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000001614 173.0
PYH2_k127_81811_5 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465,K01466 - 3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000000002931 177.0
PYH2_k127_81811_6 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000002956 149.0
PYH2_k127_81811_7 Belongs to the eukaryotic ribosomal protein eL14 family K02875 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001208 113.0
PYH2_k127_81811_8 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.00000000000000000000000008817 109.0
PYH2_k127_81811_9 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.0000000000000001682 89.0
PYH2_k127_8183566_0 PFAM Radical SAM domain protein K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 484.0
PYH2_k127_8183566_1 Glutamine cyclotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006211 251.0
PYH2_k127_8183566_2 succinyl-diaminopimelate desuccinylase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000007283 243.0
PYH2_k127_8183566_3 MFS/sugar transport protein - - - 0.0000000001658 68.0
PYH2_k127_8190680_0 Sterol carrier protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 323.0
PYH2_k127_8190680_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002607 246.0
PYH2_k127_8190680_2 Protein of unknown function (DUF1572) - - - 0.0000002883 58.0
PYH2_k127_8252082_0 small GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002904 471.0
PYH2_k127_8252082_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 327.0
PYH2_k127_8252082_2 ABC transporter K02074,K09817 - - 0.0000000000000000000000000000000000000000000000000000000001843 211.0
PYH2_k127_8252082_3 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000626 194.0
PYH2_k127_8252082_4 OsmC-like protein - - - 0.00000000000000000000000000000000000000725 149.0
PYH2_k127_8252082_5 PFAM Pyridoxamine 5'-phosphate oxidase-related K07005 - - 0.0000000000000000000000002155 111.0
PYH2_k127_8252082_6 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.0000000001388 65.0
PYH2_k127_8267744_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000002111 188.0
PYH2_k127_8267744_1 PFAM metal-dependent phosphohydrolase, HD sub domain K06950 - - 0.00000000000000000000000000000000000000009488 156.0
PYH2_k127_8267744_2 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.00000000000000000000000000000000000007836 148.0
PYH2_k127_8267744_3 hydrolase, TatD family K03424 - - 0.00000000000000000000000000000000005106 143.0
PYH2_k127_8267744_4 crossover junction endodeoxyribonuclease activity K01160 - 3.1.22.4 0.00000000000002193 78.0
PYH2_k127_8327560_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 532.0
PYH2_k127_8327560_3 - - - - 0.0000000000000001791 84.0
PYH2_k127_8327560_4 LPP20 lipoprotein - - - 0.0000000000004919 76.0
PYH2_k127_8327560_5 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000453 55.0
PYH2_k127_8331567_0 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 400.0
PYH2_k127_8331567_1 Major facilitator Superfamily K08217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006447 331.0
PYH2_k127_8331567_2 Parallel beta-helix repeats - - - 0.00000000001654 75.0
PYH2_k127_8433362_0 PFAM alanine racemase domain protein K20757 - 4.3.1.27 0.00000000000000000000000000000000000000000000000000000002368 211.0
PYH2_k127_8433362_1 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.00000000000000000000000000000000000000000003931 164.0
PYH2_k127_8433362_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000006496 89.0
PYH2_k127_8496538_0 MgtE integral membrane K07244 - - 0.000000000000000000000000000000000000000000000000000000000000009081 230.0
PYH2_k127_8496538_1 PhoU domain - - - 0.0000000000000000000000000000102 125.0
PYH2_k127_8496538_2 TrkA-C domain - - - 0.0000000000000000000000002337 111.0
PYH2_k127_8496538_3 acetyltransferase - - - 0.000001311 56.0
PYH2_k127_8533684_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 319.0
PYH2_k127_8533684_1 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000001865 232.0
PYH2_k127_8533684_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000007691 164.0
PYH2_k127_8533684_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.3.5.3 0.0000000000000000000000000000000003042 136.0
PYH2_k127_8533684_4 CDP-alcohol phosphatidyltransferase K17884 - 2.7.8.39 0.000000000000000000000000000000003378 136.0
PYH2_k127_8533684_5 - - - - 0.0000000000000000000000000000000141 137.0
PYH2_k127_8533684_6 - - - - 0.000000000000000000000000073 111.0
PYH2_k127_8533684_7 ribosomal protein K02976 - - 0.0000000000000000000000007042 107.0
PYH2_k127_8533684_8 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000001281 93.0
PYH2_k127_8533684_9 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000429 77.0
PYH2_k127_8540953_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. The Kae1 domain likely plays a direct catalytic role in this reaction. The Bud32 domain probably displays kinase activity that regulates Kae1 function K15904 - 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008858 390.0
PYH2_k127_8540953_1 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.0000000000000000000000000000000000000000000000001738 183.0
PYH2_k127_8540953_2 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001736 162.0
PYH2_k127_8540953_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000003969 161.0
PYH2_k127_8540953_4 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000001541 148.0
PYH2_k127_8568263_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 428.0
PYH2_k127_8568263_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 432.0
PYH2_k127_8568263_2 COGs COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000221 263.0
PYH2_k127_8568263_3 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K16881 - 2.7.7.13,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000002595 248.0
PYH2_k127_8568263_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000004584 214.0
PYH2_k127_8568263_5 serine threonine protein kinase K07178 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001248 215.0
PYH2_k127_8568263_6 SMART KH domain protein K06961 - - 0.00000000000000000000000000000000000000000004965 168.0
PYH2_k127_8568263_7 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000008199 108.0
PYH2_k127_8587019_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000002323 267.0
PYH2_k127_8587019_1 Ser thr protein kinase K07176 - - 0.00000000000000000000000000000000000000000000000000001008 198.0
PYH2_k127_8587019_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000007866 91.0
PYH2_k127_8639289_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 355.0
PYH2_k127_8639289_1 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000005442 186.0
PYH2_k127_8769409_0 Plug domain of Sec61p K10956 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003584 323.0
PYH2_k127_8769409_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000001483 256.0
PYH2_k127_8769409_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000005633 190.0
PYH2_k127_8769409_3 ribosomal protein K02907 - - 0.0000000000000000000000000000000000000006547 153.0
PYH2_k127_8769409_4 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000465 121.0
PYH2_k127_8769409_5 binds to the 23S rRNA K02885 - - 0.0000000000006261 70.0
PYH2_k127_8862519_0 Belongs to the RimK family K05844 - - 0.00000000000000000000002453 110.0
PYH2_k127_8862519_1 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000001229 67.0
PYH2_k127_8924590_0 Mandelate racemase muconate lactonizing enzyme K01683 - 4.2.1.5 0.000000000000000000000000000000000000000000000000000006631 204.0
PYH2_k127_8924590_1 Cupin - - - 0.00000001765 61.0
PYH2_k127_8937995_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 459.0
PYH2_k127_8937995_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 292.0
PYH2_k127_8937995_2 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003705 274.0
PYH2_k127_8937995_3 nitric oxide reductase activity - - - 0.0000000000000000000000002418 111.0
PYH2_k127_8937995_4 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0002778 52.0
PYH2_k127_8944430_0 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000121 272.0
PYH2_k127_8944430_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K00311,K17830 - 1.3.1.101,1.3.7.11,1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000006013 255.0
PYH2_k127_8944430_2 PFAM ParB domain protein nuclease - - - 0.000000000000000000000000000000000000000000000000006906 191.0
PYH2_k127_8944430_3 Binds and compact DNA (95 to 150 base pairs) to form nucleosome-like structures that contain positive DNA supercoils. Increases the resistance of DNA to thermal denaturation - - - 0.0000000000000145 75.0
PYH2_k127_8944430_4 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000003049 72.0
PYH2_k127_8965248_0 - - - - 0.00000000000000001453 92.0
PYH2_k127_9047472_0 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 395.0
PYH2_k127_9047472_1 glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000003491 199.0
PYH2_k127_9047472_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K05606 - 5.1.99.1 0.0008741 42.0
PYH2_k127_9048020_0 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 438.0
PYH2_k127_9048020_1 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000008913 210.0
PYH2_k127_9048020_2 AIR synthase related protein domain protein K04655,K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000001848 168.0
PYH2_k127_9048020_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000001908 145.0
PYH2_k127_9048020_4 Ribose-5-phosphate isomerase K01807 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0007275,GO:0008150,GO:0008219,GO:0009791,GO:0009987,GO:0010228,GO:0016853,GO:0016860,GO:0016861,GO:0022414,GO:0032501,GO:0032502,GO:0044424,GO:0044464,GO:0048608,GO:0048731,GO:0048856,GO:0061458 5.3.1.6 0.000000000000000005289 86.0
PYH2_k127_9048020_5 PFAM phosphoesterase, PA-phosphatase related K19302 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.1.27 0.0000000008459 68.0
PYH2_k127_9050243_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate - - - 6.683e-206 654.0
PYH2_k127_9050243_1 Methyltransferase domain - - - 0.000000000000000000000000895 112.0
PYH2_k127_9050243_2 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000001204 69.0
PYH2_k127_9094806_0 THUMP K06963 - - 0.00000000000000004208 89.0
PYH2_k127_9142114_0 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000005972 77.0
PYH2_k127_9142114_1 - - - - 0.000000000002724 74.0
PYH2_k127_9142114_2 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000866 70.0
PYH2_k127_9146082_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009068 409.0
PYH2_k127_9152504_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 319.0
PYH2_k127_9152504_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002922 246.0
PYH2_k127_9152504_2 Dual specificity phosphatase, catalytic domain - - - 0.00000000000000000000000000000000000000000005811 164.0
PYH2_k127_9152504_3 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000001452 164.0
PYH2_k127_9152504_4 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000009234 140.0
PYH2_k127_9152504_5 - - - - 0.000000000000000000001912 97.0
PYH2_k127_9152504_6 FtsX-like permease family - - - 0.00000000000002778 87.0
PYH2_k127_9152504_7 ethanolamine utilization protein K04019 - - 0.00000001255 62.0
PYH2_k127_9152504_8 - - - - 0.000000061 58.0
PYH2_k127_9152504_9 Protein of unknown function (DUF3795) - - - 0.000002018 52.0
PYH2_k127_9182898_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 372.0
PYH2_k127_9182898_1 TIGRFAM histidinol phosphate phosphatase HisJ K04486 - 3.1.3.15 0.0000000000000000000000000000005923 130.0
PYH2_k127_9182898_2 PFAM Uncharacterised ArCR, COG2043 - - - 0.00000000000000000008436 98.0
PYH2_k127_9182898_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000001413 90.0
PYH2_k127_9182898_4 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.000000000000000003139 96.0
PYH2_k127_9200843_0 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003852 367.0
PYH2_k127_9200843_1 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 340.0
PYH2_k127_9200843_2 Amidohydrolase K03392 - 4.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 319.0
PYH2_k127_9200843_3 PFAM DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003112 277.0
PYH2_k127_9200843_4 DNA primase K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.000000000000000000000000000000000000000000000000000000000000001576 228.0
PYH2_k127_9200843_5 DNA polymerase Ligase (LigD) K01971,K10747 GO:0000166,GO:0000287,GO:0000726,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003887,GO:0003896,GO:0003899,GO:0003909,GO:0003910,GO:0004518,GO:0004527,GO:0004529,GO:0004536,GO:0004652,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006269,GO:0006281,GO:0006302,GO:0006303,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008144,GO:0008150,GO:0008152,GO:0008296,GO:0008297,GO:0008310,GO:0008408,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016874,GO:0016886,GO:0016895,GO:0017076,GO:0018130,GO:0019438,GO:0030145,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0033554,GO:0034061,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0070566,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0097747,GO:0140097,GO:0140098,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000002177 194.0
PYH2_k127_9200843_6 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000001789 177.0
PYH2_k127_9200843_7 DNA polymerase LigD, ligase domain protein K01971 - 6.5.1.1 0.000000000000000000000000000000000000000009099 171.0
PYH2_k127_9200843_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025,K08723 - 3.1.3.5 0.000000000000000008471 93.0
PYH2_k127_9200843_9 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.0000000000009915 75.0
PYH2_k127_9213700_0 ATP hydrolysis coupled proton transport K02123 - - 0.000000000000000000000000000000002634 147.0
PYH2_k127_9213700_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0005415 49.0
PYH2_k127_9220575_0 heavy metal-(Cd Co Hg Pb Zn)-translocating K01534 - 3.6.3.3,3.6.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 548.0
PYH2_k127_9220575_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000001057 214.0
PYH2_k127_9220575_2 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000001209 205.0
PYH2_k127_9220575_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000005629 188.0
PYH2_k127_9220575_4 - - - - 0.0000000000004374 74.0
PYH2_k127_9220575_5 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K11177 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016903,GO:0030151,GO:0033554,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114 1.17.1.4 0.0000000000008578 71.0
PYH2_k127_9222853_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005128 347.0
PYH2_k127_9222853_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 304.0
PYH2_k127_9224713_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006475 357.0
PYH2_k127_9224713_1 (Rhomboid) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002271 282.0
PYH2_k127_9234626_0 TIGRFAM acetylornithine deacetylase or succinyl- diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000007266 178.0
PYH2_k127_9234626_1 Helicase K11136,K15362 - 3.6.4.12 0.0000000000000000000000000000006141 131.0
PYH2_k127_9266521_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 339.0
PYH2_k127_9266521_1 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.0000000000000000000002181 101.0
PYH2_k127_9266521_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000003523 57.0
PYH2_k127_9279715_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000477 303.0
PYH2_k127_9279715_1 DNA topoisomerase (ATP-hydrolyzing) inhibitor activity K13652,K13653 - - 0.000000000000000000000002892 107.0
PYH2_k127_9279715_2 Conserved hypothetical protein (Lin0512_fam) - - - 0.0000000000000000000003584 100.0
PYH2_k127_9279715_3 - - - - 0.0000000000000000000004061 97.0
PYH2_k127_9279715_4 Belongs to the NadC ModD family K00767,K03813 - 2.4.2.19 0.00000000000000000004235 94.0
PYH2_k127_9279715_5 Zinc finger domain - - - 0.0001734 48.0
PYH2_k127_9281324_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001763 275.0
PYH2_k127_9281324_1 - - - - 0.000000000000000000000007884 108.0
PYH2_k127_9281324_2 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.00000000000000009904 81.0
PYH2_k127_9294553_0 helicase K10896 - - 0.00000000000000000000000000000000000001388 153.0
PYH2_k127_9294553_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000005158 145.0
PYH2_k127_9294553_2 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000002016 133.0
PYH2_k127_969206_0 Thioesterase domain - - - 0.00000000000000000000000000000000000000000000000000000002819 205.0
PYH2_k127_969206_1 glutamate decarboxylase activity - - - 0.00000000000000000000000000000000000006266 149.0
PYH2_k127_969206_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000004372 141.0
PYH2_k127_969206_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.000000000000000000000000000000001619 133.0
PYH2_k127_97086_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 4.586e-209 666.0
PYH2_k127_97086_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000001083 196.0
PYH2_k127_97086_2 Sodium:sulfate symporter transmembrane region - - - 0.000000000000000000000005649 111.0
PYH2_k127_974470_0 nucleic acid-binding protein contains PIN domain - - - 0.0000000000000000000000002067 110.0
PYH2_k127_974470_1 - - - - 0.0000000000000000003319 89.0
PYH2_k127_974470_2 - - - - 0.000000000000000007317 93.0
PYH2_k127_984763_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 588.0
PYH2_k127_984763_1 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001257 251.0
PYH2_k127_984763_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000001344 69.0