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Overview

ID MAG03201
Name PYH2_bin.59
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class UBA6911
Order UBA6911
Family UBA6911
Genus
Species
Assembly information
Completeness (%) 96.07
Contamination (%) 3.73
GC content (%) 56.0
N50 (bp) 11,393
Genome size (bp) 6,269,870

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4986

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1014218_0 NHL repeat - - - 0.0000000000000000000000001762 116.0
PYH2_k127_1015646_0 Protein of unknown function, DUF255 K06888 - - 3.812e-243 770.0
PYH2_k127_1015646_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 6.583e-195 617.0
PYH2_k127_1015646_10 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.00000000000000000000000000000000000000000000000001772 182.0
PYH2_k127_1015646_11 Fibronectin type 3 domain K06882 - - 0.000000000000000000000000000000000000000001058 171.0
PYH2_k127_1015646_12 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000617 132.0
PYH2_k127_1015646_13 Zinc ion binding K11997,K12035 GO:0003008,GO:0003012,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007610,GO:0007626,GO:0008150,GO:0008152,GO:0008270,GO:0008345,GO:0009653,GO:0009987,GO:0010927,GO:0016043,GO:0016567,GO:0016740,GO:0019538,GO:0019725,GO:0019787,GO:0022607,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030154,GO:0030239,GO:0030537,GO:0031032,GO:0031674,GO:0032446,GO:0032501,GO:0032502,GO:0032989,GO:0036211,GO:0042592,GO:0042692,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043292,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044444,GO:0044449,GO:0044464,GO:0046716,GO:0046872,GO:0046914,GO:0048468,GO:0048646,GO:0048747,GO:0048856,GO:0048869,GO:0051146,GO:0055001,GO:0055002,GO:0060249,GO:0061061,GO:0065007,GO:0065008,GO:0070647,GO:0070925,GO:0071704,GO:0071840,GO:0097435,GO:0099080,GO:0099081,GO:0099512,GO:0140096,GO:1901564 2.3.2.27 0.00000000000000001005 98.0
PYH2_k127_1015646_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000002355 87.0
PYH2_k127_1015646_15 zinc ion binding - - - 0.0000008494 63.0
PYH2_k127_1015646_16 Tetratricopeptide repeat - GO:0000288,GO:0000291,GO:0000785,GO:0000956,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0019222,GO:0019439,GO:0031974,GO:0031981,GO:0032991,GO:0034641,GO:0034655,GO:0035327,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043928,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0055087,GO:0060255,GO:0065007,GO:0070013,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 - 0.0009758 51.0
PYH2_k127_1015646_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 386.0
PYH2_k127_1015646_3 COGs COG2027 D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 337.0
PYH2_k127_1015646_4 curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007611 304.0
PYH2_k127_1015646_5 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007746 301.0
PYH2_k127_1015646_6 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002584 290.0
PYH2_k127_1015646_7 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001222 282.0
PYH2_k127_1015646_8 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000009172 242.0
PYH2_k127_1015646_9 ATPase (AAA superfamily K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009301 246.0
PYH2_k127_1024719_0 arylamine N-acetyltransferase activity - - - 0.000000000000000000000000000000001281 141.0
PYH2_k127_1024719_1 Alpha beta hydrolase - - - 0.000000000000000000000000000002719 131.0
PYH2_k127_1024719_2 COG3278 Cbb3-type cytochrome oxidase, subunit 1 - - - 0.00000000000000000000000006375 113.0
PYH2_k127_1024719_3 Hypothetical methyltransferase - - - 0.00000000008566 67.0
PYH2_k127_103017_0 Thermolysin metallopeptidase, alpha-helical domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004427 441.0
PYH2_k127_103017_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008466 255.0
PYH2_k127_103017_2 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000001597 199.0
PYH2_k127_103017_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000001575 130.0
PYH2_k127_103107_0 Heat shock 70 kDa protein K04043 - - 6.89e-223 707.0
PYH2_k127_103107_1 Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008163 602.0
PYH2_k127_103107_10 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002173 283.0
PYH2_k127_103107_11 Male sterility protein K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 260.0
PYH2_k127_103107_12 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K04068,K10026 - 1.97.1.4,4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000001291 253.0
PYH2_k127_103107_13 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000001283 243.0
PYH2_k127_103107_14 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000002441 223.0
PYH2_k127_103107_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000005118 211.0
PYH2_k127_103107_16 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000006711 199.0
PYH2_k127_103107_17 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000005301 206.0
PYH2_k127_103107_18 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000002952 190.0
PYH2_k127_103107_19 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000005908 182.0
PYH2_k127_103107_2 Vault protein inter-alpha-trypsin domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 531.0
PYH2_k127_103107_20 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000002345 147.0
PYH2_k127_103107_21 Hfq protein - - - 0.0000000000000000000000000000001301 127.0
PYH2_k127_103107_22 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000001788 142.0
PYH2_k127_103107_23 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.0000000000000000000000000001118 124.0
PYH2_k127_103107_24 Belongs to the UPF0235 family K09131 - - 0.00000000000000041 82.0
PYH2_k127_103107_25 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.00000000000009945 84.0
PYH2_k127_103107_26 Type IV pilus biogenesis stability protein PilW - - - 0.00001736 53.0
PYH2_k127_103107_3 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 477.0
PYH2_k127_103107_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 444.0
PYH2_k127_103107_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 428.0
PYH2_k127_103107_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 426.0
PYH2_k127_103107_7 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000581 421.0
PYH2_k127_103107_8 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 362.0
PYH2_k127_103107_9 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 320.0
PYH2_k127_1036268_0 Carboxypeptidase regulatory-like domain - - - 1.088e-207 691.0
PYH2_k127_1036268_1 Melibiase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 627.0
PYH2_k127_1036268_10 Peptidoglycan-binding domain 1 protein K07126,K13582 - - 0.0000000000004377 75.0
PYH2_k127_1036268_11 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000002654 56.0
PYH2_k127_1036268_12 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000001546 54.0
PYH2_k127_1036268_13 Integrase core domain - - - 0.0000229 48.0
PYH2_k127_1036268_14 peptidase S41 - - - 0.00006441 57.0
PYH2_k127_1036268_15 PIN domain - - - 0.0001335 49.0
PYH2_k127_1036268_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008904 412.0
PYH2_k127_1036268_3 translation initiation factor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 372.0
PYH2_k127_1036268_4 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000001827 242.0
PYH2_k127_1036268_6 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000001027 155.0
PYH2_k127_1036268_9 - - - - 0.000000000000000007895 90.0
PYH2_k127_10410_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 484.0
PYH2_k127_10410_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 439.0
PYH2_k127_10410_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008032 411.0
PYH2_k127_10410_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 392.0
PYH2_k127_1047934_0 4Fe-4S dicluster domain K00184 - - 0.0 1216.0
PYH2_k127_1047934_1 Polysulphide reductase, NrfD K00185 - - 3.769e-213 670.0
PYH2_k127_1047934_2 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 410.0
PYH2_k127_1047934_3 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 293.0
PYH2_k127_1047934_4 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003418 233.0
PYH2_k127_1047934_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
PYH2_k127_1047934_7 - - - - 0.00000000000000006133 87.0
PYH2_k127_1051884_0 Mu transposase, C-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003468 272.0
PYH2_k127_1052624_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 531.0
PYH2_k127_1052624_1 COGs COG3316 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000001186 186.0
PYH2_k127_1052624_2 FG-GAP repeat - - - 0.00000000000000000000000000000000004543 156.0
PYH2_k127_1052624_3 PFAM Transposase IS66 family K07484 - - 0.000000000000000000009366 96.0
PYH2_k127_1052624_4 Sulfatase-modifying factor enzyme 1 - - - 0.0000006038 64.0
PYH2_k127_1067773_0 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003091 383.0
PYH2_k127_1067773_1 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.0000000000000000000000000000000000000000004687 160.0
PYH2_k127_1067773_2 Plasmid maintenance system killer K07334 - - 0.0000000000000000005184 88.0
PYH2_k127_1067773_3 - - - - 0.000000236 52.0
PYH2_k127_1069988_0 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2231.0
PYH2_k127_1069988_1 CAAX protease self-immunity K07052 - - 4.466e-232 757.0
PYH2_k127_1069988_10 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002139 274.0
PYH2_k127_1069988_11 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000009606 241.0
PYH2_k127_1069988_12 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000004857 228.0
PYH2_k127_1069988_13 Protein of unknown function (DUF1326) - - - 0.00000000000000000000000000000000000000000000000000000000006787 217.0
PYH2_k127_1069988_14 ECF sigma factor K03088 - - 0.0000000000000000000000000000000000000000002773 166.0
PYH2_k127_1069988_15 - - - - 0.00000000000000000000000000000002196 134.0
PYH2_k127_1069988_16 Protein conserved in bacteria - - - 0.00000000000000000000000000007529 128.0
PYH2_k127_1069988_17 Cold shock protein domain K03704 - - 0.000000000000000000000005181 102.0
PYH2_k127_1069988_19 23S rRNA-intervening sequence protein - - - 0.00000000000001087 75.0
PYH2_k127_1069988_2 TIGRFAM glutamate synthases, NADH NADPH, small subunit K00266 - 1.4.1.13,1.4.1.14 1.819e-231 724.0
PYH2_k127_1069988_3 Oxidoreductase family, C-terminal alpha/beta domain - - - 8.597e-216 679.0
PYH2_k127_1069988_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006053 582.0
PYH2_k127_1069988_5 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008839 603.0
PYH2_k127_1069988_6 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 398.0
PYH2_k127_1069988_7 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 361.0
PYH2_k127_1069988_8 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K01342,K08651,K14645,K14743,K20486,K20754 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0009405,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0017171,GO:0019538,GO:0030312,GO:0031224,GO:0031226,GO:0032879,GO:0040007,GO:0043170,GO:0044238,GO:0044419,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0051046,GO:0051049,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564 3.4.21.111,3.4.21.62,3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001567 295.0
PYH2_k127_1069988_9 COG0583 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004075 275.0
PYH2_k127_107845_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006374 466.0
PYH2_k127_1080216_0 response to oxidative stress K08368 GO:0005575,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0016020,GO:0044464,GO:0050896,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003248 276.0
PYH2_k127_1080216_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000316 108.0
PYH2_k127_1080216_2 domain protein - - - 0.000002727 60.0
PYH2_k127_1107430_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1055.0
PYH2_k127_1107430_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.218e-248 786.0
PYH2_k127_1107430_10 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 331.0
PYH2_k127_1107430_11 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 325.0
PYH2_k127_1107430_12 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 319.0
PYH2_k127_1107430_13 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 320.0
PYH2_k127_1107430_14 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002951 279.0
PYH2_k127_1107430_15 MotA TolQ ExbB proton channel K03561,K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001621 265.0
PYH2_k127_1107430_16 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 265.0
PYH2_k127_1107430_17 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000001927 242.0
PYH2_k127_1107430_18 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02527,K02841,K02843,K12982 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000343 229.0
PYH2_k127_1107430_19 D,d-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000000000000000257 209.0
PYH2_k127_1107430_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.116e-197 628.0
PYH2_k127_1107430_20 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000009665 207.0
PYH2_k127_1107430_21 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000286 190.0
PYH2_k127_1107430_22 TIGRFAM TonB family K03832 - - 0.00000000000000000000000000000000000000000000000007652 186.0
PYH2_k127_1107430_23 TIGRFAM geranylgeranyl reductase - - - 0.000000000000000000000000000000000000000000000001427 188.0
PYH2_k127_1107430_24 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008654,GO:0009029,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019637,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0046401,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.7.1.130 0.000000000000000000000000000000000000000000001316 179.0
PYH2_k127_1107430_25 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000002869 169.0
PYH2_k127_1107430_26 Endoribonuclease L-PSP K09022 GO:0003674,GO:0003824,GO:0016787,GO:0019239 3.5.99.10 0.000000000000000000000000000000000000000000009719 166.0
PYH2_k127_1107430_27 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000002013 149.0
PYH2_k127_1107430_28 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000004021 127.0
PYH2_k127_1107430_29 Preprotein translocase subunit K03210 - - 0.000000000000000000005264 97.0
PYH2_k127_1107430_3 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 486.0
PYH2_k127_1107430_30 Ribosomal L28 family K02902 - - 0.0000000000000000001326 89.0
PYH2_k127_1107430_31 Protein of unknown function (DUF3108) - - - 0.000000000000000005241 95.0
PYH2_k127_1107430_32 Biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000001315 82.0
PYH2_k127_1107430_33 - - - - 0.000000000008055 71.0
PYH2_k127_1107430_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 466.0
PYH2_k127_1107430_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 437.0
PYH2_k127_1107430_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 436.0
PYH2_k127_1107430_7 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 392.0
PYH2_k127_1107430_8 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000384 375.0
PYH2_k127_1107430_9 aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 369.0
PYH2_k127_1110245_0 PFAM Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000001829 227.0
PYH2_k127_1110245_1 - - - - 0.0000000000000003526 80.0
PYH2_k127_1112481_0 COG COG0383 Alpha-mannosidase - - - 5.613e-261 835.0
PYH2_k127_1112481_1 COG3119 Arylsulfatase A and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 473.0
PYH2_k127_1112481_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 328.0
PYH2_k127_1112481_3 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000699 179.0
PYH2_k127_1112481_4 Domain of unknown function (DUF1820) - - - 0.0000000000000000000000000000000000005303 142.0
PYH2_k127_1112481_5 Thiol-disulfide isomerase and - - - 0.000000000000000000000000000002703 127.0
PYH2_k127_1123604_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1189.0
PYH2_k127_1123604_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 3.179e-282 878.0
PYH2_k127_1123604_10 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 336.0
PYH2_k127_1123604_11 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000002402 212.0
PYH2_k127_1123604_12 Zn peptidase - - - 0.000000000000000000000000000000000000000000000000000000006863 215.0
PYH2_k127_1123604_13 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000177 190.0
PYH2_k127_1123604_14 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000000003668 179.0
PYH2_k127_1123604_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000008598 167.0
PYH2_k127_1123604_16 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000002679 169.0
PYH2_k127_1123604_17 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000001503 143.0
PYH2_k127_1123604_18 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K00330 - 1.6.5.3 0.000000000000000000000000000003963 123.0
PYH2_k127_1123604_19 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000000000003178 93.0
PYH2_k127_1123604_2 Prokaryotic cytochrome b561 - - - 2.843e-262 822.0
PYH2_k127_1123604_20 - - - - 0.00000000000001158 77.0
PYH2_k127_1123604_21 Putative zinc-finger - - - 0.00000000009536 72.0
PYH2_k127_1123604_22 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000001746 64.0
PYH2_k127_1123604_23 ACT domain K09707 - - 0.00000007631 61.0
PYH2_k127_1123604_24 pfam rdd - - - 0.0000002711 62.0
PYH2_k127_1123604_3 formate dehydrogenase - - - 2.918e-240 764.0
PYH2_k127_1123604_4 Permease family K06901 GO:0003674,GO:0005215,GO:0005345,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006863,GO:0008150,GO:0008324,GO:0015075,GO:0015077,GO:0015078,GO:0015205,GO:0015207,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0015851,GO:0015853,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0072530,GO:0098655,GO:0098660,GO:0098662,GO:1902600,GO:1904823 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005169 521.0
PYH2_k127_1123604_5 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 484.0
PYH2_k127_1123604_6 Galactose-1-phosphate uridyl transferase, C-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 478.0
PYH2_k127_1123604_7 ATP synthesis coupled electron transport K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 473.0
PYH2_k127_1123604_8 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 432.0
PYH2_k127_1123604_9 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 364.0
PYH2_k127_1124374_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1358.0
PYH2_k127_1124374_1 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 597.0
PYH2_k127_1124374_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 445.0
PYH2_k127_1124374_3 thiolester hydrolase activity K06889 GO:0003674,GO:0003824,GO:0016787,GO:0016788,GO:0052689 - 0.000000000000000000000000000000000000000000000000000000000000000001699 248.0
PYH2_k127_1124374_4 Histone methylation protein DOT1 - - - 0.0000000000000000000000000000000000000000000000000000000000002185 216.0
PYH2_k127_1124374_5 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000000000000000342 172.0
PYH2_k127_1124374_6 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000007566 116.0
PYH2_k127_1124374_7 transcriptional activator K03765 GO:0005575,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016020,GO:0019219,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0044464,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000000000000001421 108.0
PYH2_k127_1124374_8 lipoprotein involved in nitrous oxide reduction K19342 - - 0.0000000000000003729 85.0
PYH2_k127_1124374_9 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000001808 78.0
PYH2_k127_113198_0 Domain of unknown function (DUF5117) - - - 0.0 1061.0
PYH2_k127_113198_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.574e-287 891.0
PYH2_k127_113198_2 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 367.0
PYH2_k127_113198_3 Asparaginase K01424,K01444,K13051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.19.5,3.5.1.1,3.5.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 349.0
PYH2_k127_113198_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001167 266.0
PYH2_k127_1147257_0 Phosphotransferase System K02798,K02799,K02800 - 2.7.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 565.0
PYH2_k127_1147257_1 Creatinine amidohydrolase K01470,K22232 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 499.0
PYH2_k127_1147257_2 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 463.0
PYH2_k127_1147257_3 Xylose isomerase-like TIM barrel K22233 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001699 274.0
PYH2_k127_1147257_4 Alcohol dehydrogenase zinc-binding domain protein K17818 - 1.1.1.287 0.0000000000000000000000000000000000000000000000000000000000000000007922 241.0
PYH2_k127_1147257_5 Belongs to the PEP-utilizing enzyme family K02768,K08483,K11183,K11189 - 2.7.1.202,2.7.3.9 0.000000000000000000000009554 107.0
PYH2_k127_1147257_6 phosphocarrier K11184,K11189 - - 0.00000000000000000000971 95.0
PYH2_k127_1157172_0 Transposase, IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 536.0
PYH2_k127_1157172_1 AAA ATPase domain - - - 0.00000000002967 66.0
PYH2_k127_1161461_0 GTP-binding protein TypA K06207 - - 2.971e-261 817.0
PYH2_k127_1161461_1 acetamidase formamidase K01455 - 3.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 312.0
PYH2_k127_1161461_2 Ribosomal protein L11 methyltransferase (PrmA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000503 262.0
PYH2_k127_1163820_0 FtsX-like permease family K02004 - - 1.139e-225 716.0
PYH2_k127_1166078_0 Integrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 358.0
PYH2_k127_1166078_1 Sporulation initiation inhibitor protein Soj K03496 - - 0.00000000005745 66.0
PYH2_k127_1171447_0 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 530.0
PYH2_k127_1171447_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 337.0
PYH2_k127_1171447_2 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002625 285.0
PYH2_k127_1171447_3 Bacterial Ig-like domain (group 3) - - - 0.0000000000000008594 88.0
PYH2_k127_118783_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 407.0
PYH2_k127_118783_1 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 361.0
PYH2_k127_118783_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 344.0
PYH2_k127_118783_3 SMART band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 335.0
PYH2_k127_118783_4 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009752 295.0
PYH2_k127_118783_5 amino acid-binding ACT domain protein K04518 - 4.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000001158 269.0
PYH2_k127_118783_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000001244 180.0
PYH2_k127_118783_7 Glycosyl transferases group 1 - - - 0.0000007615 54.0
PYH2_k127_1188067_0 PFAM Type II secretion system protein E K02454,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 536.0
PYH2_k127_1188067_1 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000002236 236.0
PYH2_k127_120443_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.643e-269 852.0
PYH2_k127_120443_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 527.0
PYH2_k127_120443_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 324.0
PYH2_k127_120443_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000005967 256.0
PYH2_k127_120443_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000008674 222.0
PYH2_k127_120443_5 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000009317 189.0
PYH2_k127_120443_6 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000001011 159.0
PYH2_k127_120443_7 23S rRNA-intervening sequence protein - - - 0.0000001996 53.0
PYH2_k127_120443_9 Sporulation related domain - - - 0.000001261 61.0
PYH2_k127_1205377_0 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 514.0
PYH2_k127_1205377_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase - - - 0.000000000000000000000000000000003124 141.0
PYH2_k127_1205377_2 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.00000000000000000000000009086 115.0
PYH2_k127_1205377_4 COG0477 Permeases of the major facilitator superfamily K08153 - - 0.00000001276 67.0
PYH2_k127_1205377_5 Major facilitator superfamily - - - 0.0001356 54.0
PYH2_k127_1214003_0 Protein of unknown function (DUF1295) - - - 0.00000000000000000000000000000000000000005096 159.0
PYH2_k127_1214003_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000002785 147.0
PYH2_k127_1214003_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000000001372 145.0
PYH2_k127_1214003_3 - - - - 0.00000000000000000000000000000002512 133.0
PYH2_k127_1214003_4 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000002328 107.0
PYH2_k127_1214003_5 Integrase core domain - - - 0.00000000000003591 80.0
PYH2_k127_1214003_6 - - - - 0.00000000000006017 78.0
PYH2_k127_1214003_7 - - - - 0.000000000003915 73.0
PYH2_k127_1214003_8 integrase core domain - - - 0.000000001982 64.0
PYH2_k127_1214439_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1630.0
PYH2_k127_1214439_1 ASPIC and UnbV - - - 1.075e-202 676.0
PYH2_k127_1214439_10 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 300.0
PYH2_k127_1214439_11 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000006876 268.0
PYH2_k127_1214439_12 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000003591 242.0
PYH2_k127_1214439_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003957 211.0
PYH2_k127_1214439_2 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 523.0
PYH2_k127_1214439_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 471.0
PYH2_k127_1214439_4 MviN-like protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 452.0
PYH2_k127_1214439_5 PFAM Cys Met metabolism pyridoxal-phosphate-dependent K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 430.0
PYH2_k127_1214439_6 N-terminal domain of oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 406.0
PYH2_k127_1214439_7 Glycosyl transferase family 21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 396.0
PYH2_k127_1214439_8 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008554 340.0
PYH2_k127_1214439_9 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 301.0
PYH2_k127_1232534_0 TIGRFAM type VI secretion system Vgr family protein K11904 - - 7.783e-215 683.0
PYH2_k127_1232534_1 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 389.0
PYH2_k127_1232534_2 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000003763 198.0
PYH2_k127_1232534_3 Domain of unknown function (DUF4342) - - - 0.000000000000001155 79.0
PYH2_k127_1232534_4 A G-specific adenine glycosylase K03575 - - 0.00000009584 54.0
PYH2_k127_123337_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 398.0
PYH2_k127_1233417_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 434.0
PYH2_k127_1233417_1 Methyltransferase type 12 - - - 0.00000000000000000000000000000000000000000007801 169.0
PYH2_k127_1233417_2 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000004859 152.0
PYH2_k127_1233417_3 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000008001 76.0
PYH2_k127_1235968_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000001286 155.0
PYH2_k127_1235968_1 cell redox homeostasis - - - 0.0000000000000000000000002056 111.0
PYH2_k127_1240919_0 Major Facilitator Superfamily - - - 1.621e-203 640.0
PYH2_k127_1240919_1 - - - - 0.0000000000000000000000000000005967 126.0
PYH2_k127_1240919_2 ABC transporter K06020 - 3.6.3.25 0.0000000000000000000006496 96.0
PYH2_k127_1240919_3 - - - - 0.0000000000000000624 84.0
PYH2_k127_1252578_0 ATPase activity - - - 0.0000000000000000000000000000008345 136.0
PYH2_k127_1252578_1 - - - - 0.0000000005847 61.0
PYH2_k127_1252578_2 COG0330 Membrane protease subunits, stomatin prohibitin homologs - - - 0.000000001077 60.0
PYH2_k127_1254520_0 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004349 321.0
PYH2_k127_1254520_1 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000238 298.0
PYH2_k127_128237_0 N-acetylglucosaminylinositol deacetylase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 296.0
PYH2_k127_128237_1 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000004185 226.0
PYH2_k127_1284727_0 Domain of unknown function (DUF5107) - - - 5.813e-250 812.0
PYH2_k127_1284727_1 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 421.0
PYH2_k127_1284727_2 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001662 248.0
PYH2_k127_1284727_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000001684 205.0
PYH2_k127_1284727_4 beta-galactosidase activity K01179,K01190,K12308 - 3.2.1.23,3.2.1.4 0.000000000000000000000000000000003522 151.0
PYH2_k127_1284727_5 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000145 69.0
PYH2_k127_1307795_0 COG0553 Superfamily II DNA RNA helicases, SNF2 family K03580 - - 3.02e-201 650.0
PYH2_k127_1307795_1 - - - - 0.00000000000000000000000000000000000000000000000000000001862 212.0
PYH2_k127_1307795_2 - - - - 0.00000000000000000000000000000000000000000000000000000004325 204.0
PYH2_k127_1307795_4 Histidine kinase - - - 0.00000000001127 72.0
PYH2_k127_130951_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000001276 231.0
PYH2_k127_130951_1 Peptidase M50 - - - 0.00000000000000000000000000000000005743 141.0
PYH2_k127_130951_2 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000000000000000001347 131.0
PYH2_k127_1331902_0 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000005475 238.0
PYH2_k127_1334542_0 dipeptidase activity - - - 9.186e-229 720.0
PYH2_k127_1334542_1 TIGRFAM RHS repeat-associated core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 318.0
PYH2_k127_1334542_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001139 280.0
PYH2_k127_1334542_3 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006857 282.0
PYH2_k127_1334542_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000001632 192.0
PYH2_k127_1334542_5 6-phosphogluconolactonase activity K20952 - - 0.000000000000000000000000000000000000000000001357 191.0
PYH2_k127_1335016_0 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003446 601.0
PYH2_k127_1335016_1 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008123 354.0
PYH2_k127_1350451_0 dehydrogenases and related proteins - - - 1.602e-213 680.0
PYH2_k127_1350451_1 PFAM Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007425 437.0
PYH2_k127_1350451_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005985 381.0
PYH2_k127_1350451_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000003243 63.0
PYH2_k127_1350451_4 Lactonase, 7-bladed beta-propeller - - - 0.0000005152 61.0
PYH2_k127_1351802_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 573.0
PYH2_k127_1351802_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 581.0
PYH2_k127_1351802_10 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000001683 61.0
PYH2_k127_1351802_11 Caspase domain - - - 0.0001291 46.0
PYH2_k127_1351802_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 437.0
PYH2_k127_1351802_3 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000000001177 193.0
PYH2_k127_1351802_4 - - - - 0.00000000000000000000000000000000000000001224 154.0
PYH2_k127_1351802_5 PFAM Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000000000006373 142.0
PYH2_k127_1351802_6 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.000000000000000000000000000000000003847 139.0
PYH2_k127_1351802_7 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000001417 130.0
PYH2_k127_1351802_8 NADP oxidoreductase coenzyme F420-dependent - - - 0.00000000000000000000000159 106.0
PYH2_k127_1351802_9 FCD K05799 - - 0.0000000001514 64.0
PYH2_k127_1359498_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006298 468.0
PYH2_k127_1359498_1 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 369.0
PYH2_k127_1359498_2 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000000000000000000000000000000000000005815 193.0
PYH2_k127_1359498_3 LysM domain - - - 0.00009517 52.0
PYH2_k127_1364459_0 L-fucose isomerase, C-terminal domain - - - 2.896e-201 637.0
PYH2_k127_1364459_1 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 513.0
PYH2_k127_1364459_10 Rhamnan synthesis protein F K07272 - - 0.00000000000000000000000000000000003361 151.0
PYH2_k127_1364459_12 Peptidase M16 - - - 0.0000001468 62.0
PYH2_k127_1364459_13 Integrase - - - 0.0006314 45.0
PYH2_k127_1364459_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 466.0
PYH2_k127_1364459_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 421.0
PYH2_k127_1364459_4 PFAM Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 397.0
PYH2_k127_1364459_5 Protein conserved in bacteria K03797,K15539 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 349.0
PYH2_k127_1364459_6 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 305.0
PYH2_k127_1364459_7 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002536 259.0
PYH2_k127_1364459_8 family 2 sugar binding - - - 0.00000000000000000000000000000000000000000000000000000000000008181 224.0
PYH2_k127_1364459_9 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000001072 233.0
PYH2_k127_1365600_0 Domain of unknown function (DUF1846) - - - 2.798e-247 771.0
PYH2_k127_1365600_1 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 428.0
PYH2_k127_1365600_2 HD domain K00951 - 2.7.6.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000229 273.0
PYH2_k127_1365600_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003751 259.0
PYH2_k127_1365600_4 Sigma-70, region 4 K03088 - - 0.00000000000000000006341 98.0
PYH2_k127_1365600_5 Histidine kinase - - - 0.0000015 51.0
PYH2_k127_1365790_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 594.0
PYH2_k127_1365790_1 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005575 432.0
PYH2_k127_1365790_2 COG0534 Na -driven multidrug efflux pump K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 433.0
PYH2_k127_1365790_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488,K13819 - - 0.0000000000000000000000000000000000000000000000000000000000000008264 230.0
PYH2_k127_1365790_5 PFAM von Willebrand factor type A - - - 0.00004165 46.0
PYH2_k127_1365790_6 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000104 48.0
PYH2_k127_1372722_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 523.0
PYH2_k127_1372722_1 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 287.0
PYH2_k127_1372722_2 Transcriptional regulator IclR - - - 0.00000000000000000000000000000000000000000000000000000006032 206.0
PYH2_k127_1372722_3 indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000003381 173.0
PYH2_k127_1372722_4 - - - - 0.00000000000000000000000001533 113.0
PYH2_k127_1372722_5 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000001749 55.0
PYH2_k127_1375720_0 TonB-dependent receptor - - - 1.107e-245 800.0
PYH2_k127_1375720_1 beta-galactosidase activity - - - 1.839e-227 712.0
PYH2_k127_1375720_2 KR domain K07124 - - 0.000001183 52.0
PYH2_k127_1379490_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 565.0
PYH2_k127_1379490_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 557.0
PYH2_k127_1379490_10 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007712 287.0
PYH2_k127_1379490_11 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
PYH2_k127_1379490_12 MazG nucleotide pyrophosphohydrolase domain K02428,K02499,K04765 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006213,GO:0006220,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009147,GO:0009149,GO:0009151,GO:0009155,GO:0009164,GO:0009166,GO:0009199,GO:0009200,GO:0009203,GO:0009204,GO:0009208,GO:0009210,GO:0009211,GO:0009213,GO:0009215,GO:0009217,GO:0009218,GO:0009219,GO:0009222,GO:0009223,GO:0009259,GO:0009261,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042454,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046046,GO:0046047,GO:0046051,GO:0046052,GO:0046060,GO:0046061,GO:0046070,GO:0046075,GO:0046076,GO:0046080,GO:0046081,GO:0046131,GO:0046133,GO:0046135,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.6.1.66,3.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000005931 273.0
PYH2_k127_1379490_13 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007757 276.0
PYH2_k127_1379490_14 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000001561 266.0
PYH2_k127_1379490_15 PFAM dihydropteroate synthase, DHPS K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000008708 260.0
PYH2_k127_1379490_16 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000004423 248.0
PYH2_k127_1379490_17 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000001072 224.0
PYH2_k127_1379490_18 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000002716 191.0
PYH2_k127_1379490_19 aminopeptidase activity K07004 - - 0.00000000000000000000000000000000000000000000003764 192.0
PYH2_k127_1379490_2 TIGRFAM Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 530.0
PYH2_k127_1379490_20 Rod shape-determining protein MreC K03570 - - 0.000000000000000000000000000000000000000001204 167.0
PYH2_k127_1379490_21 Cytidylate kinase-like family - - - 0.00000000000000000007025 100.0
PYH2_k127_1379490_22 Domain of unknown function (DUF1844) - - - 0.00000000000000001312 88.0
PYH2_k127_1379490_23 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000001458 71.0
PYH2_k127_1379490_24 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000158 66.0
PYH2_k127_1379490_25 - - - - 0.00000001078 63.0
PYH2_k127_1379490_26 shape-determining protein MreD K03571 - - 0.0002651 49.0
PYH2_k127_1379490_3 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 515.0
PYH2_k127_1379490_4 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 521.0
PYH2_k127_1379490_5 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 490.0
PYH2_k127_1379490_6 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 504.0
PYH2_k127_1379490_7 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 377.0
PYH2_k127_1379490_8 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 355.0
PYH2_k127_1379490_9 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 305.0
PYH2_k127_1401620_0 Alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1124.0
PYH2_k127_1401620_1 Peptidase M14, carboxypeptidase A - - - 8.911e-289 920.0
PYH2_k127_1401620_10 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000001674 245.0
PYH2_k127_1401620_11 LmbE homologs - - - 0.000000000000000000000000000000000000000000000000000000000000000001703 235.0
PYH2_k127_1401620_12 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000005754 188.0
PYH2_k127_1401620_13 Glycine cleavage T-protein C-terminal barrel domain K00605,K06980 - 2.1.2.10 0.000000000000000000000000000000000000000000000000004353 194.0
PYH2_k127_1401620_14 protein possibly involved in utilization of glycolate and propanediol - - - 0.00000000000000000000000000000000000000000009113 166.0
PYH2_k127_1401620_15 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000000000001154 166.0
PYH2_k127_1401620_16 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0005488,GO:0005507,GO:0005575,GO:0005576,GO:0005615,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008270,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0044421,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.000000000000000000000000000000000000000009004 164.0
PYH2_k127_1401620_17 dTDP biosynthetic process K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000001716 160.0
PYH2_k127_1401620_18 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000002207 120.0
PYH2_k127_1401620_19 Transcriptional regulator - - - 0.00000000002317 72.0
PYH2_k127_1401620_2 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 1.488e-202 642.0
PYH2_k127_1401620_3 PA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 488.0
PYH2_k127_1401620_4 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 377.0
PYH2_k127_1401620_5 signal transduction protein containing EAL and modified HD-GYP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 364.0
PYH2_k127_1401620_6 Conserved protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008016 355.0
PYH2_k127_1401620_7 MFS_1 like family K08153 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 354.0
PYH2_k127_1401620_8 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 346.0
PYH2_k127_1401620_9 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 321.0
PYH2_k127_1410199_0 IMG reference gene - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 434.0
PYH2_k127_1410199_1 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001949 287.0
PYH2_k127_1410199_2 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000001222 113.0
PYH2_k127_1410199_3 - - - - 0.00000000000000000001696 97.0
PYH2_k127_1410199_4 Phage integrase family - - - 0.00000000000000000007383 96.0
PYH2_k127_1410199_5 - - - - 0.000000001448 60.0
PYH2_k127_1410199_6 PLD-like domain - - - 0.0000002959 56.0
PYH2_k127_1445943_0 COGs COG2208 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000004919 221.0
PYH2_k127_1445943_1 Predicted membrane protein (DUF2177) - - - 0.000000000000000000000000000000000000000000000006708 176.0
PYH2_k127_1445943_2 - - - - 0.000000000000000000000000000004116 127.0
PYH2_k127_1445943_3 Iron-binding zinc finger CDGSH type - - - 0.00000000000000001037 85.0
PYH2_k127_1453182_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 0.0 1141.0
PYH2_k127_1453182_1 cellulose binding - - - 0.0 1136.0
PYH2_k127_1453182_10 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 418.0
PYH2_k127_1453182_11 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006048 372.0
PYH2_k127_1453182_12 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000354 363.0
PYH2_k127_1453182_13 hydroxypyruvate isomerase activity K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003927 329.0
PYH2_k127_1453182_14 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 323.0
PYH2_k127_1453182_15 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 322.0
PYH2_k127_1453182_16 ABC-type polar amino acid transport system ATPase component K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007804 280.0
PYH2_k127_1453182_17 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002037 271.0
PYH2_k127_1453182_18 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000004764 222.0
PYH2_k127_1453182_19 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001815 173.0
PYH2_k127_1453182_2 Urocanase Rossmann-like domain K01712 - 4.2.1.49 8.01e-277 859.0
PYH2_k127_1453182_20 Domain of unknown function (DUF4824) - - - 0.000000000000000000000000000000003302 140.0
PYH2_k127_1453182_21 - - - - 0.00000000000000000146 93.0
PYH2_k127_1453182_22 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000004112 77.0
PYH2_k127_1453182_23 positive regulation of growth - - - 0.000000000031 66.0
PYH2_k127_1453182_3 ATP-dependent helicase HrpB K03579 - 3.6.4.13 7.26e-274 866.0
PYH2_k127_1453182_4 FMN binding - - - 5.778e-241 754.0
PYH2_k127_1453182_5 aminopeptidase activity K07004 - - 1.57e-222 712.0
PYH2_k127_1453182_6 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 548.0
PYH2_k127_1453182_7 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 476.0
PYH2_k127_1453182_8 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K03431,K15778 - 5.4.2.10,5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009363 463.0
PYH2_k127_1453182_9 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K08641,K11206 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 423.0
PYH2_k127_1462212_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 397.0
PYH2_k127_1462212_1 Glyoxalase-like domain K05606 GO:0003674,GO:0003824,GO:0004493,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016854,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046491,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 5.1.99.1 0.0000000000000000000000000000000000000000002612 162.0
PYH2_k127_1462212_2 ArgK protein K07588 - - 0.00000000000000919 79.0
PYH2_k127_1466812_0 FAD dependent oxidoreductase - - - 7.863e-197 626.0
PYH2_k127_1466812_1 - - - - 0.00000000000000000000000000000000000000000000000000000000001717 212.0
PYH2_k127_1466812_2 belongs to the sigma-70 factor family, ECF subfamily K03088 - - 0.0000000005747 64.0
PYH2_k127_1468533_0 Integrase core domain K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 464.0
PYH2_k127_1468533_1 Transposase - - - 0.0000000000000000000000000000000000005608 145.0
PYH2_k127_146940_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 591.0
PYH2_k127_146940_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 426.0
PYH2_k127_146940_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 342.0
PYH2_k127_146940_3 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001199 292.0
PYH2_k127_146940_4 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000007495 203.0
PYH2_k127_146940_5 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.00000000000004329 74.0
PYH2_k127_1476018_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 315.0
PYH2_k127_1476018_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008148 255.0
PYH2_k127_1476018_2 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000766 84.0
PYH2_k127_147902_0 Domain of unknown function (DUF3368) - - - 0.00000000000000000000000000000000000001093 150.0
PYH2_k127_147902_1 DNA integration - - - 0.00000000000000000000000000000000005057 136.0
PYH2_k127_147902_10 S23 ribosomal protein - - - 0.00000000000000000001913 95.0
PYH2_k127_147902_11 HEPN domain - - - 0.00000000000000000004451 101.0
PYH2_k127_147902_12 InterPro IPR007367 - - - 0.0000000000000000008274 89.0
PYH2_k127_147902_13 - - - - 0.00000000000000005165 84.0
PYH2_k127_147902_14 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000002488 74.0
PYH2_k127_147902_16 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000003208 59.0
PYH2_k127_147902_17 PFAM CopG domain protein DNA-binding domain protein - - - 0.00000003692 57.0
PYH2_k127_147902_2 Bacterial toxin of type II toxin-antitoxin system, YafQ - - - 0.00000000000000000000000000000000006673 136.0
PYH2_k127_147902_3 - - - - 0.0000000000000000000000000001146 118.0
PYH2_k127_147902_4 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000007638 115.0
PYH2_k127_147902_5 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000000000005126 110.0
PYH2_k127_147902_6 - - - - 0.00000000000000000000000006113 109.0
PYH2_k127_147902_7 PFAM PilT protein domain protein - - - 0.0000000000000000000001261 102.0
PYH2_k127_147902_8 Domain of unknown function (DUF4258) - - - 0.0000000000000000000002003 99.0
PYH2_k127_147902_9 Uncharacterised protein family (UPF0175) - - - 0.0000000000000000000005942 98.0
PYH2_k127_149963_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 519.0
PYH2_k127_149963_1 oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002362 316.0
PYH2_k127_149963_2 - - - - 0.000000000000000000000000000001104 126.0
PYH2_k127_149963_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000001892 83.0
PYH2_k127_150282_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 411.0
PYH2_k127_150282_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007132 299.0
PYH2_k127_150282_2 tetratricopeptide repeat - - - 0.00000377 49.0
PYH2_k127_1535866_0 Ketoacyl-synthetase C-terminal extension - - - 0.0 2021.0
PYH2_k127_1535866_1 Amylo-alpha-1,6-glucosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 591.0
PYH2_k127_1535866_2 4'-phosphopantetheinyl transferase superfamily K06133 - - 0.00000000000000000000000000000000000000000003702 169.0
PYH2_k127_1535866_3 DinB family - - - 0.0000000000000000000000000000000000000000001017 164.0
PYH2_k127_1535866_4 23S rRNA-intervening sequence protein - - - 0.00000000000269 69.0
PYH2_k127_1549516_0 thought to play an important role in the mineralization of sulfates catalytic activity a phenol sulfate H2O a phenol sulfate K01130 GO:0000323,GO:0001775,GO:0002252,GO:0002263,GO:0002274,GO:0002275,GO:0002283,GO:0002366,GO:0002376,GO:0002443,GO:0002444,GO:0002446,GO:0003674,GO:0003824,GO:0004065,GO:0004098,GO:0005488,GO:0005509,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005766,GO:0005773,GO:0005775,GO:0005783,GO:0005788,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006687,GO:0006807,GO:0006810,GO:0006887,GO:0006955,GO:0008150,GO:0008152,GO:0008484,GO:0009987,GO:0012505,GO:0016192,GO:0016787,GO:0016788,GO:0030141,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032940,GO:0034774,GO:0035578,GO:0036230,GO:0042119,GO:0042582,GO:0043167,GO:0043169,GO:0043202,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043299,GO:0043312,GO:0044237,GO:0044238,GO:0044255,GO:0044422,GO:0044424,GO:0044432,GO:0044433,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045321,GO:0046872,GO:0046903,GO:0050896,GO:0051179,GO:0051234,GO:0060205,GO:0070013,GO:0071704,GO:0097708,GO:0099503,GO:1901135,GO:1901564,GO:1903509 3.1.6.1 0.0 1304.0
PYH2_k127_1549516_1 PFAM glycosyl hydrolase 92 - - - 3.391e-248 772.0
PYH2_k127_1549516_2 membrane K00389 - - 0.00000000000000000000000000000000000000000000003767 173.0
PYH2_k127_1549516_3 - - - - 0.00000000000000000000000000001201 124.0
PYH2_k127_1549516_4 membrane K00389 - - 0.00000000000005165 74.0
PYH2_k127_1549516_5 Uncharacterized protein conserved in bacteria (DUF2252) - - - 0.00000001073 57.0
PYH2_k127_1555344_0 PFAM Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 566.0
PYH2_k127_1555344_1 - K02450,K03112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 320.0
PYH2_k127_1555344_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000003626 214.0
PYH2_k127_1555344_3 - - - - 0.00000000000000000000000000000000000000000000214 171.0
PYH2_k127_1577568_0 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 432.0
PYH2_k127_1577568_1 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002767 363.0
PYH2_k127_1577568_2 transmembrane transporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 342.0
PYH2_k127_1577568_3 Peptidase family M28 K05994 - 3.4.11.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008727 306.0
PYH2_k127_1577568_4 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000005238 224.0
PYH2_k127_1577568_5 PFAM DNA alkylation repair enzyme - - - 0.00000000000000001158 93.0
PYH2_k127_1577568_6 polysaccharide catabolic process K01179 - 3.2.1.4 0.00003382 57.0
PYH2_k127_1577568_7 L-seryl-tRNA selenium transferase K01042 - 2.9.1.1 0.00009733 46.0
PYH2_k127_161695_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 594.0
PYH2_k127_161695_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 522.0
PYH2_k127_161695_2 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002357 312.0
PYH2_k127_161695_3 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007748 265.0
PYH2_k127_1621183_0 RNA secondary structure unwinding K03724 - - 0.0 1444.0
PYH2_k127_1621183_1 TonB-dependent receptor - - - 0.0 1209.0
PYH2_k127_1621183_2 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 557.0
PYH2_k127_1621183_3 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 522.0
PYH2_k127_1621183_4 PFAM glycosyl transferase group 1 - - - 0.0001011 44.0
PYH2_k127_1621183_5 BNR Asp-box repeat K01186 - 3.2.1.18 0.0007365 43.0
PYH2_k127_1666005_0 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000002287 181.0
PYH2_k127_1666005_1 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000004298 177.0
PYH2_k127_1666005_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000001112 143.0
PYH2_k127_1666005_3 Pfam:Arch_ATPase - - - 0.0000000001766 65.0
PYH2_k127_1666005_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.0000003795 54.0
PYH2_k127_1666312_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 406.0
PYH2_k127_1666312_1 PA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007732 243.0
PYH2_k127_1666312_2 SnoaL-like polyketide cyclase - - - 0.0000000000000000547 85.0
PYH2_k127_1672877_0 Sodium:solute symporter family - - - 1.004e-250 786.0
PYH2_k127_1672877_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 515.0
PYH2_k127_1672877_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000001711 200.0
PYH2_k127_1672877_3 PFAM ADP-ribosylation Crystallin J1 - - - 0.000000000000000000000000000000000000000003449 169.0
PYH2_k127_1672877_4 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000007462 121.0
PYH2_k127_1672877_5 beta-lactamase - - - 0.000000000008959 68.0
PYH2_k127_1684903_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 372.0
PYH2_k127_1684903_1 Belongs to the DapB family K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000707 235.0
PYH2_k127_1701864_0 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 344.0
PYH2_k127_1701864_1 - - - - 0.00000000000000000000000000000000000000000000000000001964 191.0
PYH2_k127_1701864_2 HNH endonuclease K07451 - - 0.000000000000000000000000000000000000002072 150.0
PYH2_k127_1701864_3 DNA methylase - - - 0.0000000000000000000000002482 108.0
PYH2_k127_1701864_4 response to heat - - - 0.000000000001239 75.0
PYH2_k127_1701864_5 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000008464 58.0
PYH2_k127_171188_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 539.0
PYH2_k127_171188_1 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000121 265.0
PYH2_k127_171188_2 Belongs to the UPF0102 family K07460 - - 0.000000000000000000127 93.0
PYH2_k127_171188_3 Protein of unknown function (DUF2911) - - - 0.0000000002872 68.0
PYH2_k127_171188_5 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0002257 53.0
PYH2_k127_1749611_0 Arginase family - - - 0.0000000000000000000000000000000000000000000000000002324 195.0
PYH2_k127_1749611_1 Alkylmercury lyase - - - 0.000000000000000000009366 96.0
PYH2_k127_1749611_2 Glyoxalase-like domain - - - 0.00000000000000008378 87.0
PYH2_k127_1749611_4 Antibiotic biosynthesis monooxygenase - - - 0.00000000000001861 78.0
PYH2_k127_1749611_6 Nodulation protein S (NodS) - - - 0.0000008717 57.0
PYH2_k127_176518_0 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 583.0
PYH2_k127_1769438_0 alcohol dehydrogenase K22231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 584.0
PYH2_k127_1769438_1 Oxidoreductase family, C-terminal alpha beta domain K16043 - 1.1.1.370 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 305.0
PYH2_k127_1769438_2 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004708 291.0
PYH2_k127_1769438_3 pfkB family carbohydrate kinase - - - 0.0000000489 56.0
PYH2_k127_1774420_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000002621 206.0
PYH2_k127_1774420_1 BON domain - - - 0.000000000000000000000004448 113.0
PYH2_k127_1774420_2 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000005391 100.0
PYH2_k127_1774420_3 - - - - 0.000000000000000000004449 94.0
PYH2_k127_1774420_4 Protein of unknown function (DUF3313) - - - 0.00000000000000000009941 99.0
PYH2_k127_1774420_5 metallopeptidase activity - - - 0.00000000007369 76.0
PYH2_k127_183202_0 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000424 448.0
PYH2_k127_183202_1 Peptidase M16 inactive domain K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005489 281.0
PYH2_k127_183202_2 - - - - 0.0000000003823 70.0
PYH2_k127_185066_0 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008885 305.0
PYH2_k127_185066_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000008161 174.0
PYH2_k127_1868902_0 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 460.0
PYH2_k127_1871346_0 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002117 245.0
PYH2_k127_1871346_1 Glycosyl hydrolase family 67 N-terminus - - - 0.000000000000000000000001035 121.0
PYH2_k127_188061_0 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 289.0
PYH2_k127_188061_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000001111 123.0
PYH2_k127_188061_2 Major Facilitator Superfamily - - - 0.000000784 53.0
PYH2_k127_188061_3 DNA-templated transcription, initiation - - - 0.00051 51.0
PYH2_k127_1891301_0 helicase activity - - - 8.597e-262 829.0
PYH2_k127_1891301_1 Amino acid permease - - - 2.31e-245 779.0
PYH2_k127_1891301_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006775 579.0
PYH2_k127_1891301_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 332.0
PYH2_k127_1891301_4 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003591 259.0
PYH2_k127_1891301_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006475 255.0
PYH2_k127_1891301_6 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000000000001279 138.0
PYH2_k127_1891301_7 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000000005462 127.0
PYH2_k127_1891301_8 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000002123 91.0
PYH2_k127_1891301_9 HemY protein - - - 0.000000001006 70.0
PYH2_k127_1908546_0 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 466.0
PYH2_k127_1908546_1 outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000007708 209.0
PYH2_k127_1914532_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.115e-211 667.0
PYH2_k127_1914532_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.433e-194 631.0
PYH2_k127_1914532_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 574.0
PYH2_k127_1914532_3 Belongs to the arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 303.0
PYH2_k127_1914532_4 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.000000000000000000000000000000000000000000000000114 184.0
PYH2_k127_1914532_5 transcriptional regulator - - - 0.000000000000000000000000000000000000000000003184 171.0
PYH2_k127_1914532_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000007602 129.0
PYH2_k127_1923961_0 Alpha-L-fucosidase K01206 - 3.2.1.51 5.259e-210 661.0
PYH2_k127_1923961_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 304.0
PYH2_k127_1923961_2 - - - - 0.0000000000000000000000000000004666 128.0
PYH2_k127_1923961_3 - - - - 0.000000000000000002539 95.0
PYH2_k127_1927509_0 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008713 259.0
PYH2_k127_1927509_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000004551 213.0
PYH2_k127_1927509_2 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000003232 177.0
PYH2_k127_1945119_0 transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004827 286.0
PYH2_k127_1951125_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 557.0
PYH2_k127_1951125_1 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 313.0
PYH2_k127_1951125_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000005672 224.0
PYH2_k127_1951125_3 beta-galactosidase activity - - - 0.00000000000000000000000000000000000000000000002429 197.0
PYH2_k127_1951125_4 Melibiase K07407 - 3.2.1.22 0.000000000000000000000000000000000000000001606 164.0
PYH2_k127_1951125_5 - - - - 0.000000000000000000001231 100.0
PYH2_k127_1951125_6 TPR repeat - - - 0.000000000000001117 90.0
PYH2_k127_1951125_7 TPR repeat - - - 0.000000003481 67.0
PYH2_k127_195176_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 319.0
PYH2_k127_195176_1 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.000000152 55.0
PYH2_k127_1951990_0 Recombinase zinc beta ribbon domain K06400 - - 2.987e-194 614.0
PYH2_k127_1951990_1 Ribbon-helix-helix protein, copG family - - - 0.00000000004101 66.0
PYH2_k127_1952933_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 382.0
PYH2_k127_1952933_1 Protein conserved in bacteria K11902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000359 248.0
PYH2_k127_1952933_2 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.0000000000000000000000000000000000000000000000000000000000000000004 237.0
PYH2_k127_1952933_3 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000000000000009231 231.0
PYH2_k127_1970311_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 334.0
PYH2_k127_1970311_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003312 342.0
PYH2_k127_1970311_2 PFAM GTP cyclohydrolase I K01495 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000004636 250.0
PYH2_k127_1970311_3 PFAM MscS Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001448 259.0
PYH2_k127_1970311_4 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000001483 174.0
PYH2_k127_1970311_5 Belongs to the ompA family - - - 0.0000000000000000000001901 107.0
PYH2_k127_1970311_6 TIGRFAM YihY family protein (not ribonuclease BN) K07058 - - 0.000000000000000000003408 104.0
PYH2_k127_1970311_7 Glycosyl transferase, family 2 - - - 0.00000002359 59.0
PYH2_k127_1970311_8 HEAT repeats - - - 0.00003679 52.0
PYH2_k127_1970311_9 - - - - 0.00004835 51.0
PYH2_k127_1972838_0 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 403.0
PYH2_k127_1972838_1 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004136 345.0
PYH2_k127_1972838_2 COG1233 Phytoene dehydrogenase and related - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002081 276.0
PYH2_k127_1972838_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000109 259.0
PYH2_k127_1972838_4 transcriptional regulator - - - 0.000051 49.0
PYH2_k127_1995763_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 587.0
PYH2_k127_1995763_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 395.0
PYH2_k127_1995763_10 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000003277 183.0
PYH2_k127_1995763_11 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000001583 185.0
PYH2_k127_1995763_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000001333 165.0
PYH2_k127_1995763_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000003023 163.0
PYH2_k127_1995763_14 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000004748 138.0
PYH2_k127_1995763_15 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001093 129.0
PYH2_k127_1995763_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000005082 113.0
PYH2_k127_1995763_17 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000004442 111.0
PYH2_k127_1995763_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000009309 108.0
PYH2_k127_1995763_19 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001988 103.0
PYH2_k127_1995763_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006394 317.0
PYH2_k127_1995763_20 Ribosomal protein L30 K02907 - - 0.00000000000000009176 82.0
PYH2_k127_1995763_21 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.0000000000001414 73.0
PYH2_k127_1995763_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 286.0
PYH2_k127_1995763_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001026 266.0
PYH2_k127_1995763_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003449 246.0
PYH2_k127_1995763_6 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000000003014 228.0
PYH2_k127_1995763_7 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000003723 229.0
PYH2_k127_1995763_8 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000000000000001642 195.0
PYH2_k127_1995763_9 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000002104 183.0
PYH2_k127_1998601_0 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 477.0
PYH2_k127_1998601_1 PFAM ATP-binding region ATPase domain protein K10819 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 443.0
PYH2_k127_1998601_2 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 394.0
PYH2_k127_1998601_3 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006548 366.0
PYH2_k127_1998601_4 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 311.0
PYH2_k127_1998601_5 Transposase IS200 like - - - 0.0000000000000000000000000000000002993 140.0
PYH2_k127_1998601_6 Transposase IS200 like K07491 - - 0.00000000000000000000000000000003042 127.0
PYH2_k127_1998601_7 PFAM Major Facilitator Superfamily K08223 - - 0.000000000000000000000000000573 127.0
PYH2_k127_2003839_0 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000002328 267.0
PYH2_k127_2003839_1 - - - - 0.00000000000000000001246 101.0
PYH2_k127_2003839_2 Tetratricopeptide repeat - - - 0.00000000000000004042 90.0
PYH2_k127_2016163_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000001553 259.0
PYH2_k127_2016163_1 Integrase - - - 0.000000000000000000000000000000000000001736 156.0
PYH2_k127_2016163_2 Integrase catalytic - - - 0.000000001101 64.0
PYH2_k127_2032093_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1135.0
PYH2_k127_2032093_1 Periplasmic binding protein domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 306.0
PYH2_k127_2032093_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000001051 244.0
PYH2_k127_2032093_3 PFAM Nucleoside recognition K06373 - - 0.000000000000000000000000000000000000000000000000000000000000001912 225.0
PYH2_k127_2032093_4 Spore maturation protein K06374 - - 0.0000000000000000000000000000000000000000000000000000000009579 205.0
PYH2_k127_2032093_5 Protein of unknown function DUF115 - - - 0.000001238 59.0
PYH2_k127_2032093_6 protein kinase activity K06915 - - 0.0001341 45.0
PYH2_k127_2036805_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008416 583.0
PYH2_k127_2036805_1 TIGRFAM type VI secretion protein, VC_A0111 family K11895 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 297.0
PYH2_k127_2037629_0 AP endonuclease family 2 C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 368.0
PYH2_k127_2037629_1 Protein of unknown function (DUF421) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001895 237.0
PYH2_k127_2037629_2 - - - - 0.00000000000000000000000000000006708 126.0
PYH2_k127_2037629_3 Protein of unknown function (DUF2283) - - - 0.00000000000000000000001159 101.0
PYH2_k127_2037629_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.000000000000000000002686 100.0
PYH2_k127_2037629_5 toxin-antitoxin pair type II binding - - - 0.00000000001655 67.0
PYH2_k127_2037629_6 Integrase core domain - - - 0.0004188 49.0
PYH2_k127_2038172_0 allophanate hydrolase subunit 2 K01941,K06350 - 6.3.4.6 2.891e-268 865.0
PYH2_k127_2038172_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008108 472.0
PYH2_k127_2038172_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000004082 63.0
PYH2_k127_2038172_2 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 377.0
PYH2_k127_2038172_3 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000004026 206.0
PYH2_k127_2038172_4 creatininase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000001569 163.0
PYH2_k127_2038172_5 - - - - 0.0000000000000000000000000000000000000007742 158.0
PYH2_k127_2038172_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000107 104.0
PYH2_k127_2038172_7 - - - - 0.0000000000000000005238 97.0
PYH2_k127_2038172_8 converts alpha-aldose to the beta-anomer - - - 0.0000000000000000006587 90.0
PYH2_k127_2038172_9 metal cluster binding - - - 0.0000000001456 70.0
PYH2_k127_2038914_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 511.0
PYH2_k127_2038914_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 459.0
PYH2_k127_2038914_2 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 392.0
PYH2_k127_2038914_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001997 314.0
PYH2_k127_2038914_4 ECF sigma factor - - - 0.000000000000000000000000000000000000000000000000000000000000000000001222 241.0
PYH2_k127_2038914_5 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000000000000000001226 171.0
PYH2_k127_2038914_6 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 0.0002429 45.0
PYH2_k127_2047065_0 efflux transmembrane transporter activity - - - 1.712e-291 918.0
PYH2_k127_2047065_1 - - - - 1.153e-239 757.0
PYH2_k127_2047065_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 432.0
PYH2_k127_2047065_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000008379 74.0
PYH2_k127_2047065_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000001358 59.0
PYH2_k127_2048590_0 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008141 443.0
PYH2_k127_2048590_1 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000003757 201.0
PYH2_k127_2048590_2 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000003317 126.0
PYH2_k127_2048590_3 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.0000000000000000000001197 102.0
PYH2_k127_2048590_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000019 91.0
PYH2_k127_2050412_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 488.0
PYH2_k127_2050412_1 VanZ like family - - - 0.00000000000000000000000000000000000005879 159.0
PYH2_k127_2051811_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 501.0
PYH2_k127_2051811_1 protein secretion K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.000000000000000000000000000000000012 138.0
PYH2_k127_2051811_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000008685 137.0
PYH2_k127_2051811_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000000003528 119.0
PYH2_k127_2051811_4 Polymer-forming cytoskeletal - - - 0.000000000000000000001638 95.0
PYH2_k127_2051832_0 COG3119 Arylsulfatase A K01130 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 515.0
PYH2_k127_2051832_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 521.0
PYH2_k127_2051832_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000003678 194.0
PYH2_k127_2051832_3 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000009895 156.0
PYH2_k127_2051832_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000131 70.0
PYH2_k127_2051832_5 Immune inhibitor A peptidase M6 K09607 - - 0.00000007109 57.0
PYH2_k127_2069324_0 serine-type exopeptidase activity K01322 GO:0005575,GO:0005623,GO:0042597,GO:0044464 3.4.21.26 3.039e-318 989.0
PYH2_k127_2069324_1 Dihydroorotate dehydrogenase - - - 6.339e-264 841.0
PYH2_k127_2069324_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.24e-217 689.0
PYH2_k127_2069324_3 Aldehyde dehydrogenase family K00140,K22187 - 1.2.1.18,1.2.1.27 2.191e-209 661.0
PYH2_k127_2069324_4 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 359.0
PYH2_k127_2069324_5 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001999 259.0
PYH2_k127_2069324_6 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000001641 197.0
PYH2_k127_2080481_0 amino acid - - - 5.767e-238 752.0
PYH2_k127_2080481_1 Predicted membrane protein (DUF2339) - - - 2.517e-236 771.0
PYH2_k127_2080481_10 phosphoglycerate kinase activity K00927,K01803 GO:0003674,GO:0003824,GO:0004618,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576 2.7.2.3,5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 476.0
PYH2_k127_2080481_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 458.0
PYH2_k127_2080481_12 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000368 371.0
PYH2_k127_2080481_13 Phosphoenolpyruvate phosphomutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 304.0
PYH2_k127_2080481_14 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 299.0
PYH2_k127_2080481_15 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000121 304.0
PYH2_k127_2080481_16 GtrA-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009193 259.0
PYH2_k127_2080481_17 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000663 261.0
PYH2_k127_2080481_18 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000006682 213.0
PYH2_k127_2080481_19 PFAM Organic solvent tolerance protein K04744 - - 0.000000000000000000000000000000000000000000000000000002555 209.0
PYH2_k127_2080481_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 1.597e-228 719.0
PYH2_k127_2080481_20 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000009108 190.0
PYH2_k127_2080481_21 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000001325 179.0
PYH2_k127_2080481_22 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000000000000003264 158.0
PYH2_k127_2080481_23 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 0.000000000000000000000000000000000000009169 147.0
PYH2_k127_2080481_24 NUDIX domain - - - 0.00000000000000000000000000000000000003215 150.0
PYH2_k127_2080481_25 Domain of unknown function DUF302 - - - 0.0000000000000000000000000000000000003639 144.0
PYH2_k127_2080481_26 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000003891 115.0
PYH2_k127_2080481_27 Vitamin B12 dependent methionine synthase, activation domain protein - - - 0.0000000000000000000000001967 116.0
PYH2_k127_2080481_28 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000009364 113.0
PYH2_k127_2080481_29 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000002648 95.0
PYH2_k127_2080481_3 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 4.59e-199 627.0
PYH2_k127_2080481_30 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.0000000000001185 85.0
PYH2_k127_2080481_31 Archease protein family (MTH1598/TM1083) - - - 0.0000000000001519 77.0
PYH2_k127_2080481_32 Mycolic acid cyclopropane synthetase - - - 0.00000000001211 73.0
PYH2_k127_2080481_4 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 600.0
PYH2_k127_2080481_5 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 600.0
PYH2_k127_2080481_6 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 550.0
PYH2_k127_2080481_7 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 507.0
PYH2_k127_2080481_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 499.0
PYH2_k127_2080481_9 RNA ligase activity K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 479.0
PYH2_k127_2084777_0 domain protein - - - 1.937e-279 873.0
PYH2_k127_2084777_1 COGs COG4299 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 360.0
PYH2_k127_2084777_2 Sel1-like repeats. - - - 0.000000000000000002622 98.0
PYH2_k127_2088109_0 Belongs to the glycosyl hydrolase 2 family K01190 - 3.2.1.23 0.0 1128.0
PYH2_k127_2088109_1 Pectate lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 542.0
PYH2_k127_2088109_2 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000008624 254.0
PYH2_k127_2088109_3 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000002661 205.0
PYH2_k127_2088109_4 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000009624 181.0
PYH2_k127_2088109_5 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.00000000000000000000000000002545 129.0
PYH2_k127_2088109_6 Saccharopine dehydrogenase C-terminal domain - - - 0.00000003556 57.0
PYH2_k127_2092176_0 Sulfatase - - - 5.4e-268 837.0
PYH2_k127_2092176_1 Putative MetA-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000003138 167.0
PYH2_k127_2092176_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000002642 157.0
PYH2_k127_2097625_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 5.103e-274 852.0
PYH2_k127_2097625_1 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009689 608.0
PYH2_k127_2097625_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 423.0
PYH2_k127_2097625_3 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 349.0
PYH2_k127_2097625_4 DinB family - - - 0.0000000000000000000000000000000000000000000000000003992 188.0
PYH2_k127_2097625_5 electron transfer activity K02275,K02305,K08738,K17223 - 1.9.3.1 0.0000000000000000000000000000813 123.0
PYH2_k127_2102110_0 Transposase IS66 family K07484 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 387.0
PYH2_k127_2102110_1 Domain of unknown function (DUF4338) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003171 282.0
PYH2_k127_2121389_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 7.666e-262 819.0
PYH2_k127_2121389_1 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 489.0
PYH2_k127_2121389_2 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 389.0
PYH2_k127_2122684_0 Molybdenum Cofactor Synthesis C K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 311.0
PYH2_k127_2122684_1 Integrase - - - 0.0000000000000000002139 93.0
PYH2_k127_2122684_2 4Fe-4S binding domain - - - 0.0000000000000007402 81.0
PYH2_k127_2123006_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.308e-218 691.0
PYH2_k127_2123006_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 518.0
PYH2_k127_2123006_2 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 437.0
PYH2_k127_2123006_3 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 437.0
PYH2_k127_2123006_4 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 411.0
PYH2_k127_2123006_5 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 317.0
PYH2_k127_2123006_6 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 303.0
PYH2_k127_2123006_7 Pfam:DUF2029 - - - 0.000000000002832 79.0
PYH2_k127_2123006_8 Glycosyltransferase family 87 K13671 - - 0.00000003668 66.0
PYH2_k127_2129224_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.558e-223 721.0
PYH2_k127_2129224_1 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 558.0
PYH2_k127_2129224_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006733 423.0
PYH2_k127_2129224_3 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 336.0
PYH2_k127_2129224_4 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000005831 232.0
PYH2_k127_2129224_5 ECF sigma factor K03088 - - 0.00000000000000000000000000000001455 135.0
PYH2_k127_2129224_6 - - - - 0.00000000000000000000001617 104.0
PYH2_k127_2129224_7 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000001423 74.0
PYH2_k127_2131072_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 397.0
PYH2_k127_2131072_1 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004186 274.0
PYH2_k127_2150372_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004117 322.0
PYH2_k127_215132_0 Uncharacterised protein family (UPF0182) K09118 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 2.049e-250 806.0
PYH2_k127_215132_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 608.0
PYH2_k127_215132_10 Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000004392 164.0
PYH2_k127_215132_11 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000001201 177.0
PYH2_k127_215132_12 Transcriptional regulator - - - 0.0000000000000000000000000001711 119.0
PYH2_k127_215132_13 glyoxalase III activity - - - 0.00005811 52.0
PYH2_k127_215132_2 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 437.0
PYH2_k127_215132_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 401.0
PYH2_k127_215132_4 pfam abc K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 290.0
PYH2_k127_215132_5 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004471 282.0
PYH2_k127_215132_6 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000000000000000000000000003071 226.0
PYH2_k127_215132_7 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000002847 210.0
PYH2_k127_215132_8 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000006813 177.0
PYH2_k127_215132_9 - - - - 0.00000000000000000000000000000000000000000003643 173.0
PYH2_k127_216491_0 Serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 316.0
PYH2_k127_216491_1 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000000000001767 170.0
PYH2_k127_216491_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000003527 137.0
PYH2_k127_216491_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000002344 99.0
PYH2_k127_2171303_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001648 254.0
PYH2_k127_2171303_1 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.000000000000000000000000000000000000000000000007783 188.0
PYH2_k127_2213225_0 DNA binding domain with preference for A/T rich regions K07491 - - 0.0000000000000000000000000000000000000000000000000001638 195.0
PYH2_k127_2213225_1 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000002196 87.0
PYH2_k127_2213225_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000000001021 76.0
PYH2_k127_2255593_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 310.0
PYH2_k127_2255593_1 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000007991 226.0
PYH2_k127_2255593_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0006950,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0010467,GO:0015934,GO:0015968,GO:0016043,GO:0019538,GO:0019843,GO:0022411,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0032984,GO:0032991,GO:0033554,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0042594,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0051716,GO:0065003,GO:0070925,GO:0071496,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000006127 207.0
PYH2_k127_2255593_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000004094 123.0
PYH2_k127_2255593_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000001051 88.0
PYH2_k127_2255593_5 structural constituent of ribosome K02913 - - 0.000000000000000016 82.0
PYH2_k127_2255593_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000001124 53.0
PYH2_k127_2255593_7 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000001215 54.0
PYH2_k127_2261996_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 403.0
PYH2_k127_2261996_1 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001466 253.0
PYH2_k127_2261996_10 Pentapeptide repeats (9 copies) - - - 0.000000000000002734 87.0
PYH2_k127_2261996_11 toxin-antitoxin pair type II binding - - - 0.000000000031 66.0
PYH2_k127_2261996_12 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0009522 42.0
PYH2_k127_2261996_2 Calcineurin-like phosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000004369 248.0
PYH2_k127_2261996_3 enterotoxin - - - 0.00000000000000000000000000000000000000000000000001809 202.0
PYH2_k127_2261996_4 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000001351 154.0
PYH2_k127_2261996_5 beta-galactosidase activity - - - 0.000000000000000000000000000000005018 149.0
PYH2_k127_2261996_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000196 114.0
PYH2_k127_2261996_7 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000002156 113.0
PYH2_k127_2261996_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.00000000000000000000001212 104.0
PYH2_k127_2261996_9 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.000000000000000001925 88.0
PYH2_k127_2267789_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 401.0
PYH2_k127_2267789_1 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006976 403.0
PYH2_k127_2267789_10 Isochorismatase family K08281 - 3.5.1.19 0.0000000000000000000000000000000000003205 148.0
PYH2_k127_2267789_11 - - - - 0.000000000000000001013 100.0
PYH2_k127_2267789_13 - - - - 0.0001428 52.0
PYH2_k127_2267789_2 synthetase, class II (G H P K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 403.0
PYH2_k127_2267789_3 PFAM PfkB domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 390.0
PYH2_k127_2267789_4 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 353.0
PYH2_k127_2267789_5 Involved in the biosynthesis of porphyrin-containing compound - GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001261 288.0
PYH2_k127_2267789_6 pfkB family carbohydrate kinase K18478 - 2.7.1.184 0.0000000000000000000000000000000000000000000000000000000000000000000000003253 258.0
PYH2_k127_2267789_7 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000000000001687 211.0
PYH2_k127_2267789_8 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000005759 174.0
PYH2_k127_2267789_9 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000002197 164.0
PYH2_k127_2301153_0 Amidohydrolase family - - - 1.738e-199 640.0
PYH2_k127_2301153_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 501.0
PYH2_k127_2301153_2 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 296.0
PYH2_k127_2301153_3 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000003981 172.0
PYH2_k127_2301153_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000000002159 146.0
PYH2_k127_2301153_5 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000003221 122.0
PYH2_k127_2301153_6 PFAM GCN5-related N-acetyltransferase - - - 0.000000002481 65.0
PYH2_k127_2301195_0 Putative esterase - - - 5.74e-267 836.0
PYH2_k127_2301195_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000006554 82.0
PYH2_k127_2301410_0 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003489 255.0
PYH2_k127_2301410_1 SIS domain - - - 0.000000000000000000000000000000001721 132.0
PYH2_k127_2334122_0 Large extracellular alpha-helical protein K06894 - - 0.0 1942.0
PYH2_k127_2334122_1 GMC oxidoreductase - - - 9.319e-265 826.0
PYH2_k127_2334122_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002628 237.0
PYH2_k127_2334122_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000008285 242.0
PYH2_k127_2334122_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000001425 227.0
PYH2_k127_2334122_13 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000005595 160.0
PYH2_k127_2334122_15 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000006929 96.0
PYH2_k127_2334122_16 diguanylate cyclase - - - 0.00000001519 64.0
PYH2_k127_2334122_17 DNA integration - - - 0.0000003049 59.0
PYH2_k127_2334122_2 Carboxypeptidase regulatory-like domain - - - 7.003e-243 784.0
PYH2_k127_2334122_3 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 1.143e-208 674.0
PYH2_k127_2334122_4 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 497.0
PYH2_k127_2334122_5 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 335.0
PYH2_k127_2334122_6 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 323.0
PYH2_k127_2334122_7 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 307.0
PYH2_k127_2334122_8 Phytase K01083 - 3.1.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 308.0
PYH2_k127_2334122_9 Copper binding periplasmic protein CusF K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006818 270.0
PYH2_k127_233557_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 2.02e-216 681.0
PYH2_k127_233557_1 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.812e-206 653.0
PYH2_k127_233557_2 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009675 278.0
PYH2_k127_233557_3 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000002835 255.0
PYH2_k127_2343557_0 efflux transmembrane transporter activity - - - 0.0000000000000000000000000002686 117.0
PYH2_k127_2343557_1 nuclease activity K06218 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0006139,GO:0006355,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0019219,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0034641,GO:0034655,GO:0040008,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0045892,GO:0045926,GO:0045934,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000001027 111.0
PYH2_k127_2343557_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000006683 118.0
PYH2_k127_2343557_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000001047 80.0
PYH2_k127_2343984_0 metallocarboxypeptidase activity - - - 1.184e-249 788.0
PYH2_k127_2343984_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 4.244e-225 711.0
PYH2_k127_2343984_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 353.0
PYH2_k127_2343984_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 291.0
PYH2_k127_2343984_4 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000001929 164.0
PYH2_k127_2343984_5 Nucleoside diphosphate-linked moiety X motif 22 - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0008768,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0031974,GO:0031981,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046872,GO:0070013 - 0.000000001881 68.0
PYH2_k127_234970_0 Carboxypeptidase regulatory-like domain - - - 0.0 1232.0
PYH2_k127_234970_1 alpha-L-rhamnosidase - - - 2.59e-288 914.0
PYH2_k127_234970_2 - - - - 5.473e-205 654.0
PYH2_k127_234970_3 WD40 domain protein beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001072 301.0
PYH2_k127_235760_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1027.0
PYH2_k127_235760_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 623.0
PYH2_k127_235760_10 PFAM cytoplasmic chaperone TorD family protein - - - 0.0000000122 66.0
PYH2_k127_235760_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001794 65.0
PYH2_k127_235760_2 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 505.0
PYH2_k127_235760_3 COG COG3119 Arylsulfatase A and related enzymes K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 353.0
PYH2_k127_235760_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 - 4.1.99.22,4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 345.0
PYH2_k127_235760_5 histidine kinase dimerisation and phosphoacceptor region - - - 0.000000000000000000000000000000000000000000000000002912 200.0
PYH2_k127_235760_6 PFAM Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000000005263 188.0
PYH2_k127_235760_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000151 149.0
PYH2_k127_235760_8 4Fe-4S binding domain - - - 0.000000000000000000000005196 116.0
PYH2_k127_235760_9 carboxylic acid catabolic process - - - 0.00000000000000000000001102 104.0
PYH2_k127_2384950_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000002028 220.0
PYH2_k127_2384950_1 metal-dependent hydrolase of the TIM-barrel fold - - - 0.0000000000000000000000000000000002579 138.0
PYH2_k127_240355_0 - - - - 1.044e-203 657.0
PYH2_k127_240355_1 PFAM oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 574.0
PYH2_k127_240355_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 458.0
PYH2_k127_240355_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009522 320.0
PYH2_k127_240355_4 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000000000000000000000000000000000000002272 199.0
PYH2_k127_240355_5 Domain of unknown function (DUF4160) - - - 0.0000000000000000000000000000000000003098 145.0
PYH2_k127_240355_6 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000002963 113.0
PYH2_k127_240355_7 Lactoylglutathione lyase K05606 - 5.1.99.1 0.0000000000000000004193 99.0
PYH2_k127_240355_8 - - - - 0.00001302 52.0
PYH2_k127_2415001_0 competence protein COMEC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 472.0
PYH2_k127_2415001_1 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 432.0
PYH2_k127_2415001_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000005356 87.0
PYH2_k127_2434377_0 Cytochrome c554 and c-prime - - - 0.0 1236.0
PYH2_k127_2434377_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0 1163.0
PYH2_k127_2434377_10 Aldo/keto reductase family K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 467.0
PYH2_k127_2434377_11 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 459.0
PYH2_k127_2434377_12 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 432.0
PYH2_k127_2434377_13 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 411.0
PYH2_k127_2434377_14 electron transport chain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000634 388.0
PYH2_k127_2434377_15 electron transport chain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009012 389.0
PYH2_k127_2434377_16 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 384.0
PYH2_k127_2434377_17 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 361.0
PYH2_k127_2434377_18 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 330.0
PYH2_k127_2434377_19 Radical_SAM C-terminal domain K07139 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051539,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 334.0
PYH2_k127_2434377_2 ASPIC and UnbV - - - 1.215e-291 903.0
PYH2_k127_2434377_20 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009095 331.0
PYH2_k127_2434377_21 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 302.0
PYH2_k127_2434377_22 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 288.0
PYH2_k127_2434377_24 Beta-ketoacyl synthase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006899 263.0
PYH2_k127_2434377_25 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000007358 248.0
PYH2_k127_2434377_26 PFAM Retinal pigment epithelial membrane protein K00464 - 1.13.11.75 0.0000000000000000000000000000000000000000000000000000000004198 220.0
PYH2_k127_2434377_27 Voltage gated chloride channel K03281 - - 0.00000000000000000000000000000000000000000000000000000000653 216.0
PYH2_k127_2434377_28 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.000000000000000000000000000000000000000000000000000000007822 208.0
PYH2_k127_2434377_29 TIGRFAM 2-polyprenylphenol 6-hydroxylase K03688 - - 0.00000000000000000000000000000000000000000000000000003405 209.0
PYH2_k127_2434377_3 acetolactate synthase K01652 GO:0000287,GO:0003674,GO:0003824,GO:0003984,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0019842,GO:0030976,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1901681 2.2.1.6 9.771e-278 865.0
PYH2_k127_2434377_30 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000001643 186.0
PYH2_k127_2434377_31 Phosphate acyltransferases - - - 0.0000000000000000000000000000000000000000000003196 187.0
PYH2_k127_2434377_32 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000001424 162.0
PYH2_k127_2434377_33 Halogenase - - - 0.000000000000000000000000000000000000000002068 173.0
PYH2_k127_2434377_34 PFAM Anion-transporting ATPase - - - 0.00000000000000000000000000000000000000002733 166.0
PYH2_k127_2434377_35 3-hydroxymyristoyl 3-hydroxydecanoyl-(acyl carrier protein) K02372 - 4.2.1.59 0.00000000000000000000000000000000000007589 147.0
PYH2_k127_2434377_36 esterase of the alpha-beta hydrolase superfamily K07001 GO:0003674,GO:0003824,GO:0016787 - 0.0000000000000000000000000000000000006309 159.0
PYH2_k127_2434377_37 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000148 100.0
PYH2_k127_2434377_38 cyclic nucleotide binding K09766,K10914 - - 0.00000000000000001507 94.0
PYH2_k127_2434377_4 Heparinase II/III-like protein - - - 7.504e-214 685.0
PYH2_k127_2434377_40 alginic acid biosynthetic process K20276 - - 0.000000000001121 79.0
PYH2_k127_2434377_41 Halogenase - - - 0.000000000001261 72.0
PYH2_k127_2434377_42 Bacterial Ig-like domain (group 1) - - - 0.0000000003592 71.0
PYH2_k127_2434377_43 Phosphopantetheine attachment site K02078 - - 0.00000001061 59.0
PYH2_k127_2434377_44 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000434 62.0
PYH2_k127_2434377_45 ABC1 family K03688 - - 0.0002782 53.0
PYH2_k127_2434377_46 oligoketide cyclase lipid transport protein - GO:0003674,GO:0005488,GO:0006417,GO:0006446,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0043021,GO:0043023,GO:0044877,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0080090,GO:2000112,GO:2000113 - 0.000888 49.0
PYH2_k127_2434377_5 Receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 538.0
PYH2_k127_2434377_6 L-fucose isomerase and related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 511.0
PYH2_k127_2434377_7 cobalamin-transporting ATPase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 506.0
PYH2_k127_2434377_8 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 486.0
PYH2_k127_2434377_9 PFAM Na dependent nucleoside transporter K03317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 478.0
PYH2_k127_2450551_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 417.0
PYH2_k127_2450551_1 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000004391 215.0
PYH2_k127_2450551_2 - - - - 0.000000000000000000000000000000000000000000000008654 182.0
PYH2_k127_2450551_3 Binding-protein-dependent transport system inner membrane component K15552 - - 0.0000000000000000000000000000000000000001198 161.0
PYH2_k127_2453309_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003636 248.0
PYH2_k127_2453309_2 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000004283 233.0
PYH2_k127_2453309_4 Transposase K07484,K20444 - - 0.00000000007852 70.0
PYH2_k127_2453309_5 Integrin alpha (beta-propellor repeats). - - - 0.0000000006725 73.0
PYH2_k127_2453309_6 Mannosyltransferase (PIG-V) - - - 0.0000002165 63.0
PYH2_k127_2453309_7 Autotransporter beta-domain - - - 0.000004537 61.0
PYH2_k127_2453458_0 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 565.0
PYH2_k127_2453458_1 Amino acid kinase family K12524 - 1.1.1.3,2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009624 577.0
PYH2_k127_2453458_2 Permease, YjgP YjgQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 456.0
PYH2_k127_2453458_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 397.0
PYH2_k127_2453458_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 402.0
PYH2_k127_2453458_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 343.0
PYH2_k127_2453458_6 recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006722 293.0
PYH2_k127_2453458_7 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000002024 208.0
PYH2_k127_2464043_0 response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 364.0
PYH2_k127_2464043_1 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006055 283.0
PYH2_k127_2464043_2 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000000000000000000000000001306 210.0
PYH2_k127_2464043_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000004379 182.0
PYH2_k127_2464043_4 PFAM flagellar FlbD family protein K02385 - - 0.00000000002985 66.0
PYH2_k127_2464043_5 - - - - 0.000000001253 65.0
PYH2_k127_2465369_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K00605,K18847 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10,2.2.1.8 4.784e-316 995.0
PYH2_k127_2465369_1 microcin C7 resistance K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 445.0
PYH2_k127_2465369_2 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 333.0
PYH2_k127_2465369_3 Periplasmic or secreted lipoprotein - - - 0.00000000000000000000000000000000000002122 155.0
PYH2_k127_2476033_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 326.0
PYH2_k127_2476033_1 4Fe-4S dicluster domain K14091 - - 0.00000000000000000000000000000000000000003045 154.0
PYH2_k127_2476033_2 ATP synthase B/B' CF(0) K02109 - - 0.000000000000000000000000001262 119.0
PYH2_k127_2476033_3 ATP synthase subunit C K02110 - - 0.0000000000000000000174 93.0
PYH2_k127_2490210_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 542.0
PYH2_k127_2490210_1 Amino acid kinase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 477.0
PYH2_k127_2490210_2 hydrolase activity, acting on ester bonds K22369 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 336.0
PYH2_k127_2490210_3 family 2 sugar binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 291.0
PYH2_k127_2490210_4 translation initiation factor activity K03496,K09000 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0008150,GO:0009295,GO:0016020,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044424,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000002843 238.0
PYH2_k127_2490210_5 L-rhamnose mutarotase K03534 - 5.1.3.32 0.00000000000000000000000000000000000000000000005654 171.0
PYH2_k127_2490210_6 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000003793 97.0
PYH2_k127_2517266_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 481.0
PYH2_k127_2517266_1 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006751 466.0
PYH2_k127_2517266_2 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008479 291.0
PYH2_k127_2517266_3 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000019 231.0
PYH2_k127_2517266_4 candidate rhamnogalacturonan lyase, polysaccharide lyase family 11 protein K01238 K18197 - 4.2.2.23 0.00000000000000000000000000000000000000000000000000000000000159 236.0
PYH2_k127_2517266_5 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.0000000000000000000000001118 124.0
PYH2_k127_2517266_6 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000003919 88.0
PYH2_k127_2544574_0 TIGRFAM ornithine aminotransferase K00819 - 2.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 614.0
PYH2_k127_2544574_1 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 613.0
PYH2_k127_2544574_10 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000005142 108.0
PYH2_k127_2544574_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 595.0
PYH2_k127_2544574_3 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 578.0
PYH2_k127_2544574_4 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005047 529.0
PYH2_k127_2544574_5 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003969 441.0
PYH2_k127_2544574_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 428.0
PYH2_k127_2544574_7 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 339.0
PYH2_k127_2544574_8 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000003333 214.0
PYH2_k127_2544574_9 Glucose-6-phosphate dehydrogenase subunit - - - 0.000000000000000000000000000000000000002577 161.0
PYH2_k127_2549635_0 DNA-binding transcription factor activity K03892 - - 0.000000000000000000000000000000007901 132.0
PYH2_k127_2549635_1 Thioredoxin K03671 - - 0.000000000000000000000000000001221 135.0
PYH2_k127_2549635_2 Arsenical resistance operon trans-acting repressor ArsD - - - 0.0000000000000000000000001864 113.0
PYH2_k127_2549635_3 Pfam Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000001146 74.0
PYH2_k127_2549635_4 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000001348 77.0
PYH2_k127_2549635_5 Regulatory protein, FmdB family - - - 0.00000002369 57.0
PYH2_k127_2551762_0 protocatechuate 3,4-dioxygenase activity - - - 0.0 1281.0
PYH2_k127_2551762_1 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 407.0
PYH2_k127_2551762_2 myo-inosose-2 dehydratase activity - - - 0.00000000000000000003153 93.0
PYH2_k127_2551762_4 Integrase core domain - - - 0.0001157 50.0
PYH2_k127_2556696_0 Integrase core domain - - - 1.661e-201 640.0
PYH2_k127_2556696_1 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 329.0
PYH2_k127_2592428_0 Transposase DDE domain - - - 1.595e-225 713.0
PYH2_k127_2592428_1 Helix-turn-helix domain - - - 0.00000000000000000000002576 103.0
PYH2_k127_2592428_2 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000003238 84.0
PYH2_k127_261720_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 526.0
PYH2_k127_261720_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003453 293.0
PYH2_k127_261720_2 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.000000000000000000000000000000000000000000000001166 185.0
PYH2_k127_261720_4 Tetratricopeptide repeat - - - 0.000001638 59.0
PYH2_k127_2620771_0 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 439.0
PYH2_k127_2620771_1 Transposase - - - 0.00000000000000001009 89.0
PYH2_k127_2653837_0 pfkB family carbohydrate kinase K00874 - 2.7.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 328.0
PYH2_k127_2653837_1 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000006893 184.0
PYH2_k127_2653837_2 C4-type zinc ribbon domain K07164 - - 0.00000000000000000004129 100.0
PYH2_k127_2653837_3 KDPG and KHG aldolase - - - 0.000000002561 67.0
PYH2_k127_2653837_4 membrane organization K07277 GO:0005575,GO:0005623,GO:0008104,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032991,GO:0033036,GO:0034613,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044425,GO:0044462,GO:0044464,GO:0045184,GO:0045229,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071709,GO:0071840,GO:0071944,GO:0072657,GO:0090150,GO:0098552,GO:0098796,GO:1990063 - 0.00003864 50.0
PYH2_k127_2665866_0 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000493 374.0
PYH2_k127_2665866_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001933 244.0
PYH2_k127_2665866_2 Winged helix DNA-binding domain - - - 0.000000236 52.0
PYH2_k127_2672931_0 COG1943 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001269 266.0
PYH2_k127_2716308_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 577.0
PYH2_k127_2716308_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 340.0
PYH2_k127_2716308_2 EcsC protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 336.0
PYH2_k127_2716308_3 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002704 243.0
PYH2_k127_2716308_4 PIN domain K07063 - - 0.00000000000000000000000000000000000000002488 156.0
PYH2_k127_2716308_5 PIN domain - - - 0.0000000000000000000000000000000001761 137.0
PYH2_k127_2716308_6 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000000000000000000000001161 115.0
PYH2_k127_2716308_7 PFAM SpoVT AbrB K07172,K18842 - - 0.0000000000000000001819 89.0
PYH2_k127_2716308_8 Plasmid stability protein K21495 - - 0.0000000000001704 74.0
PYH2_k127_2722070_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 521.0
PYH2_k127_2722070_1 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 485.0
PYH2_k127_2722070_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000004225 121.0
PYH2_k127_2726656_0 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 541.0
PYH2_k127_2726656_1 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 354.0
PYH2_k127_2726656_2 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000843 152.0
PYH2_k127_2726656_3 Peptidoglycan-binding domain 1 protein K01447,K07126,K13582 - 3.5.1.28 0.000000000000000000000000000000001881 138.0
PYH2_k127_2726656_4 Sulfate permease family K03321 - - 0.0000000000000000000002593 102.0
PYH2_k127_2726656_5 protein trimerization K01206,K07114,K07126 - 3.2.1.51 0.000000000000000001057 97.0
PYH2_k127_2726902_0 PFAM TonB-dependent Receptor Plug - - - 0.000000000000000000000000000000000000000000002612 185.0
PYH2_k127_2726902_1 Sulfate permease family K03321 - - 0.00000000000000000000000000000001234 128.0
PYH2_k127_2726902_2 Protein of unknown function (DUF3303) - - - 0.00000000000000000000006187 100.0
PYH2_k127_2726902_3 PIN domain - - - 0.00000000002128 65.0
PYH2_k127_2726902_4 NmrA-like family - - - 0.0000000203 56.0
PYH2_k127_2726902_5 Domain of unknown function (DUF4440) - - - 0.00000072 56.0
PYH2_k127_2726902_6 Transcriptional regulator, Crp Fnr family - - - 0.0007066 46.0
PYH2_k127_2739152_0 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 578.0
PYH2_k127_2739152_1 - K02450,K03112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006088 323.0
PYH2_k127_2739152_2 AAA domain - - - 0.00000000000000000000000000000000000000000000000000001835 203.0
PYH2_k127_2739152_3 - - - - 0.0000000000000000000000000000000000000000001609 166.0
PYH2_k127_2739807_0 His Kinase A (phosphoacceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007205 425.0
PYH2_k127_2739807_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000002426 93.0
PYH2_k127_2739807_2 GyrI-like small molecule binding domain - - - 0.000000006172 61.0
PYH2_k127_2740139_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1071.0
PYH2_k127_2740139_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.23e-212 674.0
PYH2_k127_2740139_2 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000001076 172.0
PYH2_k127_2740139_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000719 129.0
PYH2_k127_2740139_4 of the drug metabolite transporter (DMT) superfamily - - - 0.0001123 48.0
PYH2_k127_2766573_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 362.0
PYH2_k127_2766573_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 298.0
PYH2_k127_2766573_11 histidine kinase A domain protein domain protein - - - 0.00001294 58.0
PYH2_k127_2766573_2 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000205 282.0
PYH2_k127_2766573_3 amino acid ABC transporter K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001128 280.0
PYH2_k127_2766573_4 pseudouridine synthase activity K06177,K06179,K06180 - 5.4.99.23,5.4.99.24,5.4.99.28,5.4.99.29 0.0000000000000000000000000000000000000000000000000000000000000000000007927 243.0
PYH2_k127_2766573_5 Alanine racemase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000106 210.0
PYH2_k127_2766573_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000001216 126.0
PYH2_k127_2766573_7 Prokaryotic N-terminal methylation motif K08084 - - 0.0000000000000000000000006286 111.0
PYH2_k127_2766573_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000007814 104.0
PYH2_k127_2766573_9 pilus assembly protein PilW - - - 0.0000000009058 69.0
PYH2_k127_2785028_0 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 418.0
PYH2_k127_2785028_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 351.0
PYH2_k127_2785028_2 PFAM peptidase K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 327.0
PYH2_k127_2785028_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000001183 150.0
PYH2_k127_2791945_0 Penicillin amidase K07116 - 3.5.1.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 456.0
PYH2_k127_2791945_1 S1/P1 Nuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000009654 232.0
PYH2_k127_2791945_2 - - - - 0.000000000000000000001333 99.0
PYH2_k127_280019_0 Transposase IS116 IS110 IS902 family protein - - - 0.00000000000000000000000000000000000004478 156.0
PYH2_k127_280019_1 Protein of unknown function DUF86 - - - 0.000000000000000000001534 97.0
PYH2_k127_2801725_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000076 419.0
PYH2_k127_2801725_1 PFAM peptidase S58, DmpA K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 323.0
PYH2_k127_2801725_2 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000001356 134.0
PYH2_k127_2801725_3 Redoxin K03564 - 1.11.1.15 0.00000000001376 66.0
PYH2_k127_2801725_4 Protein of unknown function (DUF1573) - - - 0.0000003208 58.0
PYH2_k127_2801725_5 Protein of unknown function (DUF1573) - - - 0.000001691 53.0
PYH2_k127_2816505_0 exo-alpha-(2->6)-sialidase activity K01179,K07093,K12056,K12516,K20074 GO:0000287,GO:0001932,GO:0001933,GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006469,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009892,GO:0009987,GO:0010563,GO:0010605,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019220,GO:0019222,GO:0019538,GO:0030145,GO:0030312,GO:0031224,GO:0031226,GO:0031323,GO:0031324,GO:0031399,GO:0031400,GO:0032268,GO:0032269,GO:0033673,GO:0036211,GO:0042325,GO:0042326,GO:0042578,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043392,GO:0043412,GO:0043549,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0045859,GO:0045936,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0051098,GO:0051100,GO:0051101,GO:0051171,GO:0051172,GO:0051174,GO:0051246,GO:0051248,GO:0051338,GO:0051348,GO:0060255,GO:0065007,GO:0065009,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 3.1.3.16,3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 565.0
PYH2_k127_2816505_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 525.0
PYH2_k127_2816505_10 Aldo/keto reductase family K07079 - - 0.00000002883 59.0
PYH2_k127_2816505_11 Metallo-beta-lactamase superfamily - - - 0.0000001884 58.0
PYH2_k127_2816505_13 Domain of unknown function (DUF362) - - - 0.0003298 53.0
PYH2_k127_2816505_2 short-chain dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000003147 209.0
PYH2_k127_2816505_3 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000005767 201.0
PYH2_k127_2816505_4 Transcriptional regulator K22293 - - 0.000000000000000000000000000000000000000005161 164.0
PYH2_k127_2816505_5 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.00000000000000000000000000000000000001788 148.0
PYH2_k127_2816505_6 beta-1,4-mannooligosaccharide phosphorylase K20885 - 2.4.1.339,2.4.1.340 0.00000000000000000009646 90.0
PYH2_k127_2816505_8 DJ-1/PfpI family - - - 0.0000000000002486 69.0
PYH2_k127_2816505_9 transcriptional regulator K07726 - - 0.0000000007859 65.0
PYH2_k127_282960_0 COG3119 Arylsulfatase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005278 246.0
PYH2_k127_282960_1 Acetyl xylan esterase (AXE1) - - - 0.000000000000000000000000000003564 127.0
PYH2_k127_2836720_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.422e-258 804.0
PYH2_k127_2836720_1 SMART band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000509 323.0
PYH2_k127_2836720_10 - - - - 0.0004714 52.0
PYH2_k127_2836720_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K19715 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0016051,GO:0043170,GO:0044238,GO:0071704,GO:1901576 2.6.1.109 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 299.0
PYH2_k127_2836720_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001057 257.0
PYH2_k127_2836720_4 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000005494 219.0
PYH2_k127_2836720_5 - - - - 0.00000000000000000000000000000000000001469 157.0
PYH2_k127_2836720_6 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.00000000000000000000000000000000000003307 145.0
PYH2_k127_2836720_7 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000007462 70.0
PYH2_k127_2836720_8 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000004739 63.0
PYH2_k127_2836720_9 Amino acid permease - - - 0.00007461 51.0
PYH2_k127_2837395_0 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000001798 209.0
PYH2_k127_2837395_1 - - - - 0.00000000000000000000000000000000000000000000002159 180.0
PYH2_k127_2837395_2 SNARE associated Golgi protein - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000009596 166.0
PYH2_k127_2837395_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000001108 163.0
PYH2_k127_2837395_4 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.000000000000000000000000000000000000115 147.0
PYH2_k127_2837395_5 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.0000000000000000000000000000000000002909 145.0
PYH2_k127_2837395_6 EamA-like transporter family - - - 0.0000000000000000000000000000008335 133.0
PYH2_k127_2837395_7 mRNA capping enzyme, catalytic domain K01971 - 6.5.1.1 0.0000000000000003083 89.0
PYH2_k127_2837395_8 Belongs to the anti-sigma-factor antagonist family K06378 - - 0.000000001675 63.0
PYH2_k127_2837395_9 E-Z type HEAT repeats - - - 0.0001122 53.0
PYH2_k127_2839683_0 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 389.0
PYH2_k127_2839683_1 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 304.0
PYH2_k127_2849530_0 transposition, DNA-mediated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004038 431.0
PYH2_k127_2849530_1 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000006645 117.0
PYH2_k127_2849530_2 - - - - 0.000000000000000004025 89.0
PYH2_k127_2854817_0 PFAM Mandelate racemase muconate lactonizing enzyme, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 582.0
PYH2_k127_2854817_1 PFAM Orn DAP Arg decarboxylase 2 K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 549.0
PYH2_k127_2854817_2 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 433.0
PYH2_k127_2854817_3 RelA SpoT domain protein - - - 0.000000000000000000000000000000000000000000000000000000009002 224.0
PYH2_k127_2854817_4 PFAM Stress responsive A B Barrel Domain - - - 0.0000000000000000000000000000000002022 142.0
PYH2_k127_2854817_5 Peptidase C39 family K06147 - - 0.00000000003723 72.0
PYH2_k127_2854817_6 Thioredoxin-like - - - 0.0000000533 61.0
PYH2_k127_2859508_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 529.0
PYH2_k127_2859508_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 366.0
PYH2_k127_2859508_2 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 326.0
PYH2_k127_2859508_3 transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003301 259.0
PYH2_k127_2859508_4 lyase activity - - - 0.000000000000000000000000000000001177 143.0
PYH2_k127_2859508_5 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000007217 141.0
PYH2_k127_2859508_6 - - - - 0.000000000000000000004283 96.0
PYH2_k127_2859508_7 - - - - 0.00000001204 63.0
PYH2_k127_2859508_8 - - - - 0.00000001839 62.0
PYH2_k127_2865029_0 Pyridoxal-dependent decarboxylase conserved domain K13745 - 4.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 544.0
PYH2_k127_2865029_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 529.0
PYH2_k127_2865029_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 429.0
PYH2_k127_2865029_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000002125 189.0
PYH2_k127_2865029_4 diguanylate cyclase - - - 0.0000000000000000000000000000000009908 141.0
PYH2_k127_2865029_5 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000005397 98.0
PYH2_k127_2865029_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000001217 105.0
PYH2_k127_2865029_7 DoxX - - - 0.0000000000000000001554 93.0
PYH2_k127_2865029_8 amino acid activation for nonribosomal peptide biosynthetic process K17713 - - 0.0000000000000295 88.0
PYH2_k127_2865029_9 - - - - 0.000001235 51.0
PYH2_k127_2865330_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 1.981e-222 709.0
PYH2_k127_2865330_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 380.0
PYH2_k127_2865330_10 HDOD domain - - - 0.00000000000000000000000000000000000000000000002867 182.0
PYH2_k127_2865330_11 Flagellar rod assembly protein muramidase FlgJ K02395,K08259,K08309,K21472 - 3.4.24.75 0.00000000000000000000000000000000000009978 153.0
PYH2_k127_2865330_12 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000000009155 149.0
PYH2_k127_2865330_13 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.0000000000000000000000000000000001024 141.0
PYH2_k127_2865330_14 Type III flagellar switch regulator (C-ring) FliN C-term K02417 - - 0.000000000000000000000002892 107.0
PYH2_k127_2865330_15 TIGRFAM flagellar motor switch protein FliN K02417 - - 0.000000000000000003328 88.0
PYH2_k127_2865330_16 Role in flagellar biosynthesis K02420 - - 0.000000000000000007943 86.0
PYH2_k127_2865330_17 PFAM Type II secretion system protein E K02652 - - 0.0000000000000001402 90.0
PYH2_k127_2865330_18 TIGRFAM Flagellar hook-associated protein, FlgK K02396 - - 0.00000000000001533 76.0
PYH2_k127_2865330_19 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.00000001176 66.0
PYH2_k127_2865330_2 flagellar basal-body rod protein FlgG K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 314.0
PYH2_k127_2865330_21 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.0002999 44.0
PYH2_k127_2865330_22 Anti-sigma-28 factor, FlgM K02398 - - 0.0004488 47.0
PYH2_k127_2865330_23 FlgN protein - - - 0.0005096 49.0
PYH2_k127_2865330_3 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002943 274.0
PYH2_k127_2865330_4 flagellar motor switch protein FliM K02416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004444 272.0
PYH2_k127_2865330_5 TIGRFAM RNA polymerase sigma factor, FliA WhiG family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007249 267.0
PYH2_k127_2865330_6 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002844 263.0
PYH2_k127_2865330_7 bacterial-type flagellum organization K02282,K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000001971 243.0
PYH2_k127_2865330_8 Flagellar biosynthesis K02404 - - 0.000000000000000000000000000000000000000000000000003691 196.0
PYH2_k127_2865330_9 PFAM flagellar basal body rod protein K02392 - - 0.0000000000000000000000000000000000000000000000005258 184.0
PYH2_k127_2876221_0 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 469.0
PYH2_k127_2876221_1 Carbon-nitrogen hydrolase - - - 0.000000000005112 74.0
PYH2_k127_2876221_2 COG1943 Transposase and inactivated derivatives - - - 0.00000000094 62.0
PYH2_k127_2876221_3 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0008326 44.0
PYH2_k127_2888676_0 Putative restriction endonuclease - - - 0.00000000000000000000000000000000000000000000000000000002519 202.0
PYH2_k127_2888676_1 Putative restriction endonuclease - - - 0.000000000000000000000000000000000000000000000000002772 187.0
PYH2_k127_2888676_2 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000000000006397 132.0
PYH2_k127_2888676_3 Transposase IS116/IS110/IS902 family K07486 - - 0.0000000000005879 80.0
PYH2_k127_2889457_0 Cell shape determining protein MreB Mrl K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 379.0
PYH2_k127_2889457_1 enterobactin catabolic process K07214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 366.0
PYH2_k127_2889457_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 301.0
PYH2_k127_2889457_3 N-Acetylmuramoyl-L-alanine amidase K11066,K12287 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002848 290.0
PYH2_k127_2889457_4 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000003839 232.0
PYH2_k127_2889457_5 transposition K07497 - - 0.00000000000001422 78.0
PYH2_k127_2889806_0 Integrase core domain - - - 0.00000000000000008374 82.0
PYH2_k127_2889806_1 Belongs to the glycosyl hydrolase 32 family K01119 - 3.1.3.6,3.1.4.16 0.0000000006788 70.0
PYH2_k127_2889806_2 serine-type peptidase activity K01990,K08884,K12132,K18912 - 1.14.99.50,2.7.11.1 0.000000006148 63.0
PYH2_k127_2889806_3 - - - - 0.000000548 58.0
PYH2_k127_2889806_4 Integrase core domain - - - 0.0000006168 54.0
PYH2_k127_2891416_0 ABC transporter K17215 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 512.0
PYH2_k127_2891416_1 PFAM Periplasmic binding protein LacI transcriptional regulator K10439,K17213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008646 377.0
PYH2_k127_2891416_2 Belongs to the binding-protein-dependent transport system permease family K17214 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 361.0
PYH2_k127_2891416_3 converts alpha-aldose to the beta-anomer - - - 0.000000000000000000000000000000000000000000000000000000000004215 214.0
PYH2_k127_2892731_0 Protein of unknown function (DUF4038) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 556.0
PYH2_k127_2892731_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 564.0
PYH2_k127_2892731_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 413.0
PYH2_k127_2892731_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 389.0
PYH2_k127_2892731_4 Phosphogluconate dehydrogenase (decarboxylating) C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 337.0
PYH2_k127_2892731_5 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000001065 184.0
PYH2_k127_2892731_6 - - - - 0.0000000000000000000000000000000000000000000001848 184.0
PYH2_k127_2892731_7 Dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000364 101.0
PYH2_k127_2892731_8 TonB-dependent receptor - - - 0.00000000000000000006294 94.0
PYH2_k127_2892731_9 Xylose isomerase-like TIM barrel - - - 0.00000000000000000118 87.0
PYH2_k127_2910210_0 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 512.0
PYH2_k127_2910210_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008761 409.0
PYH2_k127_2910210_2 phage integrase family K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 314.0
PYH2_k127_2920819_0 serine-type peptidase activity K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 380.0
PYH2_k127_2920819_1 protein histidine kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 356.0
PYH2_k127_2920819_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 284.0
PYH2_k127_2920819_3 PIN domain - - - 0.00000000000000000000000000009856 119.0
PYH2_k127_2920819_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000166 87.0
PYH2_k127_2920819_5 SpoVT / AbrB like domain - - - 0.00000000000003794 74.0
PYH2_k127_2920819_7 serine-type peptidase activity K03641 - - 0.000004003 50.0
PYH2_k127_2920819_8 - - - - 0.0001792 48.0
PYH2_k127_2921170_0 Belongs to the peptidase S16 family - - - 0.0006323 53.0
PYH2_k127_2923805_0 TonB-dependent Receptor Plug Domain - - - 1.312e-242 782.0
PYH2_k127_2923805_1 membrane K07148 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 355.0
PYH2_k127_2923805_2 - - - - 0.000000000000000000000000000000000000000000000000009263 188.0
PYH2_k127_2923805_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000694 122.0
PYH2_k127_2924692_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 435.0
PYH2_k127_2924692_1 alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 297.0
PYH2_k127_2924692_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000008037 164.0
PYH2_k127_2924692_3 DMSO reductase anchor subunit K07308 - - 0.000000003999 68.0
PYH2_k127_2948464_0 PFAM Integrase catalytic region - - - 3.315e-203 645.0
PYH2_k127_2948464_1 Bacterial dnaA protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009082 364.0
PYH2_k127_2948464_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000216 150.0
PYH2_k127_2948738_0 TonB-dependent receptor K13735,K20276 - - 2.637e-214 703.0
PYH2_k127_2948738_1 cAMP biosynthetic process - - - 0.00000000000000000000000000000000002431 143.0
PYH2_k127_2948738_2 Encoded by - - - 0.00000000001688 68.0
PYH2_k127_2948738_3 anaphase-promoting complex binding - - - 0.0000000001827 63.0
PYH2_k127_2963166_0 N-acetylglucosaminylinositol deacetylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 362.0
PYH2_k127_2963166_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001509 265.0
PYH2_k127_2965811_0 Sulfatase - - - 1.653e-221 721.0
PYH2_k127_2965811_1 COG3119 Arylsulfatase A and related enzymes K01138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 590.0
PYH2_k127_2965811_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 386.0
PYH2_k127_2965811_3 GDSL-like Lipase/Acylhydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003256 271.0
PYH2_k127_2965811_4 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.0000000000000000000000000000000000000000000000000000005764 197.0
PYH2_k127_2965811_5 - - - - 0.00000000000000000000000004447 113.0
PYH2_k127_2965811_7 lactoylglutathione lyase activity - - - 0.0000000002419 62.0
PYH2_k127_2967565_0 Tetratricopeptide repeats K12132 - 2.7.11.1 7.017e-236 753.0
PYH2_k127_2967565_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000003143 205.0
PYH2_k127_2972299_0 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 366.0
PYH2_k127_2972299_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
PYH2_k127_2972299_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005483 266.0
PYH2_k127_2972299_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000003629 212.0
PYH2_k127_2972299_4 Domain of unknown function (DUF4126) - - - 0.000000000000000000000000000000000000000000000000001415 189.0
PYH2_k127_2972299_5 - - - - 0.000000000000000000000000000000000000006229 151.0
PYH2_k127_2972299_7 ester cyclase - - - 0.00000000000003446 78.0
PYH2_k127_2972299_8 - - - - 0.000000001085 68.0
PYH2_k127_2973089_0 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 621.0
PYH2_k127_2973089_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 426.0
PYH2_k127_2973089_2 PFAM ATP-binding region, ATPase domain protein domain protein K07683 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 316.0
PYH2_k127_2973089_3 Response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002219 277.0
PYH2_k127_2973089_4 PFAM glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001652 264.0
PYH2_k127_2973089_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007372 261.0
PYH2_k127_2973089_6 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000002412 215.0
PYH2_k127_2973089_7 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000005877 207.0
PYH2_k127_2973089_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000001485 146.0
PYH2_k127_2973089_9 Amidohydrolase - - - 0.0003276 44.0
PYH2_k127_2990421_0 phosphate-selective porin O and P - - - 0.0000000000000022 89.0
PYH2_k127_2990421_1 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000007478 80.0
PYH2_k127_3005241_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003671 477.0
PYH2_k127_3005241_1 RNA polymerase sigma-54 factor K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 389.0
PYH2_k127_3005241_2 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 312.0
PYH2_k127_3005241_3 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002507 279.0
PYH2_k127_3005241_4 PTS system fructose IIA component K02793,K02794,K02821 - 2.7.1.191,2.7.1.194 0.0000000000000000000000000000000000002022 145.0
PYH2_k127_3005241_5 lipopolysaccharide transport K09774 - - 0.0000000000000000000000000005941 132.0
PYH2_k127_3005241_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000002772 111.0
PYH2_k127_3005241_7 Phosphotransferase System K11189 - - 0.00000000000000000006836 92.0
PYH2_k127_3006707_0 Putative transposase - - - 0.000000000000000000000000000000003022 136.0
PYH2_k127_3007232_0 Zinc carboxypeptidase K14054 - - 0.0 1260.0
PYH2_k127_3007232_1 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
PYH2_k127_3007232_3 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 391.0
PYH2_k127_3007232_4 Methyltransferase FkbM domain - - - 0.00000000000000000000007536 109.0
PYH2_k127_3007232_5 - - - - 0.0000000000000000000003314 104.0
PYH2_k127_3037752_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 634.0
PYH2_k127_3037752_1 addiction module antidote protein, HigA family K21498 - - 0.00000003833 54.0
PYH2_k127_3037752_2 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0001499 45.0
PYH2_k127_3041613_0 Carboxypeptidase regulatory-like domain - - - 1.893e-232 754.0
PYH2_k127_3041613_1 hydrogenase large subunit K00436 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000001386 209.0
PYH2_k127_3041613_2 fatty acid responsive transcription factor FadR domain protein K03603 - - 0.0000000000000000000000000000000000000003081 159.0
PYH2_k127_3041613_3 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000009279 143.0
PYH2_k127_3041613_4 hydrogenase maturation protease - - - 0.000000000000000000000006837 108.0
PYH2_k127_3041613_5 response regulator - - - 0.00000000008988 68.0
PYH2_k127_3048815_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168,K07479 GO:0003674,GO:0003824,GO:0003916,GO:0003917,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016853,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.2 3.454e-275 869.0
PYH2_k127_3048815_1 elongation factor Tu domain 2 protein K02355 - - 5.933e-238 754.0
PYH2_k127_3048815_10 PFAM von Willebrand factor type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000006482 239.0
PYH2_k127_3048815_11 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000004178 202.0
PYH2_k127_3048815_12 negative regulation of transcription, DNA-templated - - - 0.00000000000000000000002234 105.0
PYH2_k127_3048815_13 chaperone-mediated protein folding K12132 - 2.7.11.1 0.00000000000000004803 96.0
PYH2_k127_3048815_14 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00008055 46.0
PYH2_k127_3048815_2 Amino acid permease - - - 7.498e-195 617.0
PYH2_k127_3048815_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 601.0
PYH2_k127_3048815_4 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 369.0
PYH2_k127_3048815_5 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 295.0
PYH2_k127_3048815_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000608 271.0
PYH2_k127_3048815_7 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002781 263.0
PYH2_k127_3048815_8 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 268.0
PYH2_k127_3048815_9 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003844 249.0
PYH2_k127_3054850_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1133.0
PYH2_k127_3054850_1 PFAM Diol glycerol dehydratase, large subunit K01699,K06120 - 4.2.1.28,4.2.1.30 2.409e-222 711.0
PYH2_k127_3054850_10 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000001422 228.0
PYH2_k127_3054850_11 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000001841 182.0
PYH2_k127_3054850_12 dehydratase medium subunit K13919 - 4.2.1.28 0.00000000000000000000000000000000000000000000001726 194.0
PYH2_k127_3054850_13 Dehydratase small subunit K13920 - 4.2.1.28 0.0000000000000000000000000000000001109 137.0
PYH2_k127_3054850_14 Peptidase M1, membrane alanine aminopeptidase - - - 0.0000000000000000005382 102.0
PYH2_k127_3054850_15 Methyltransferase domain - - - 0.00000000000002071 83.0
PYH2_k127_3054850_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 627.0
PYH2_k127_3054850_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004043 603.0
PYH2_k127_3054850_4 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 486.0
PYH2_k127_3054850_5 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 370.0
PYH2_k127_3054850_6 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 308.0
PYH2_k127_3054850_7 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001161 289.0
PYH2_k127_3054850_8 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001148 252.0
PYH2_k127_3054850_9 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000004311 241.0
PYH2_k127_3056036_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1224.0
PYH2_k127_3056036_1 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 0.0 1019.0
PYH2_k127_3056036_10 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 376.0
PYH2_k127_3056036_11 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 389.0
PYH2_k127_3056036_12 CoA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 383.0
PYH2_k127_3056036_13 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 370.0
PYH2_k127_3056036_14 Chain length determinant protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000701 351.0
PYH2_k127_3056036_15 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 295.0
PYH2_k127_3056036_16 Glycosyl transferase WecB/TagA/CpsF family K05946 - 2.4.1.187 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
PYH2_k127_3056036_17 Heterodisulfide reductase, subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003941 283.0
PYH2_k127_3056036_18 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009812 264.0
PYH2_k127_3056036_19 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001378 250.0
PYH2_k127_3056036_2 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 2.822e-233 738.0
PYH2_k127_3056036_20 PFAM Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000001458 239.0
PYH2_k127_3056036_21 CO dehydrogenase acetyl-CoA synthase K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000002435 235.0
PYH2_k127_3056036_22 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000002628 237.0
PYH2_k127_3056036_23 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000005227 224.0
PYH2_k127_3056036_24 FtsZ-dependent cytokinesis - - - 0.000000000000000000000000000000000000000000000000000002763 209.0
PYH2_k127_3056036_25 polysaccharide biosynthetic process - - - 0.00000000000000000000000000000000000000000001233 179.0
PYH2_k127_3056036_26 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000009757 162.0
PYH2_k127_3056036_27 Methyltransferase domain - - - 0.00000000000000000000000000000000000001011 156.0
PYH2_k127_3056036_28 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000003272 151.0
PYH2_k127_3056036_29 response regulator - - - 0.000000000000000000000000427 113.0
PYH2_k127_3056036_3 PFAM Polysaccharide export protein - - - 2.27e-210 698.0
PYH2_k127_3056036_30 sulfolactate sulfo-lyase activity K01685,K16845 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.7,4.4.1.24 0.0000000000000000000000004376 109.0
PYH2_k127_3056036_31 spore germination K03605 - - 0.00000000000000000000001074 109.0
PYH2_k127_3056036_32 Domain of unknown function (DUF3786) - - - 0.0000000000000000000001198 109.0
PYH2_k127_3056036_33 Methyltransferase domain - - - 0.000000000000000000003663 103.0
PYH2_k127_3056036_34 CHRD domain - - - 0.000000000001145 74.0
PYH2_k127_3056036_35 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.00000006674 57.0
PYH2_k127_3056036_36 O-Antigen ligase - - - 0.00003235 56.0
PYH2_k127_3056036_37 helix_turn _helix lactose operon repressor K02529 - - 0.0009174 44.0
PYH2_k127_3056036_4 Citrate lyase, alpha subunit (CitF) - - - 8.332e-207 653.0
PYH2_k127_3056036_5 hydrogenase large subunit K14126 - 1.8.98.5 1.96e-200 640.0
PYH2_k127_3056036_6 D-galactarate dehydratase / Altronate hydrolase, C terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 536.0
PYH2_k127_3056036_7 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 474.0
PYH2_k127_3056036_8 Aldehyde dehydrogenase family K00135,K07248 - 1.2.1.16,1.2.1.20,1.2.1.21,1.2.1.22,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 483.0
PYH2_k127_3056036_9 Glycosyltransferase, group 1 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 409.0
PYH2_k127_307057_0 Pfam:GBA2_N K17108 - 3.2.1.45 0.000000000000000005486 98.0
PYH2_k127_307057_1 PFAM ribonuclease II K01147 - 3.1.13.1 0.00000005072 57.0
PYH2_k127_3086713_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 396.0
PYH2_k127_3086713_1 DNA-templated transcription, initiation K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001238 289.0
PYH2_k127_3086713_10 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000001276 76.0
PYH2_k127_3086713_11 TIGRFAM conserved repeat domain - - - 0.0000501 55.0
PYH2_k127_3086713_2 N-terminus of Esterase_SGNH_hydro-type - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003059 251.0
PYH2_k127_3086713_3 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006327 254.0
PYH2_k127_3086713_4 Belongs to the glycosyl hydrolase 32 family K03332 - 3.2.1.80 0.00000000000000000000000000000000000000000000000000000000000000009355 231.0
PYH2_k127_3086713_5 methyltransferase activity K21310 - 2.1.1.334 0.000000000000000000000000000000000000000000001442 171.0
PYH2_k127_3086713_6 HicB_like antitoxin of bacterial toxin-antitoxin system K18843 - - 0.0000000000000000000000000000000000000000002341 164.0
PYH2_k127_3086713_7 CarD-like/TRCF domain K07736 - - 0.000000000000000000000000000000000000007102 153.0
PYH2_k127_3086713_8 transposition K07497,K09958 - - 0.000000000000000000005188 94.0
PYH2_k127_3086713_9 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000001821 89.0
PYH2_k127_3087189_0 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 354.0
PYH2_k127_3087189_1 GDP-mannose 4,6 dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000004496 167.0
PYH2_k127_3090133_0 Glycosyl hydrolase family 65, N-terminal domain - - - 1.84e-274 861.0
PYH2_k127_3090133_1 Bacterial Ig-like domain (group 1) - - - 0.00000000000000000000000000000000000000000004115 186.0
PYH2_k127_3090133_2 Conserved repeat domain K06045 - 4.2.1.129,5.4.99.17 0.0000137 59.0
PYH2_k127_3111335_0 COGs COG1132 ABC-type multidrug transport system ATPase and permease components K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007023 542.0
PYH2_k127_3111335_1 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000000004229 176.0
PYH2_k127_3111335_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000001052 99.0
PYH2_k127_3117432_0 Carboxypeptidase regulatory-like domain - - - 2.104e-249 801.0
PYH2_k127_3117432_1 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000581 117.0
PYH2_k127_31248_0 metallocarboxypeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 554.0
PYH2_k127_31248_1 Transposase and inactivated derivatives K07498 - - 0.000000000000000002783 86.0
PYH2_k127_3131300_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1508.0
PYH2_k127_3146010_0 PFAM DNA methylase N-4 N-6 - - - 0.00000000000000000000000000000000000000000000001601 181.0
PYH2_k127_3146010_1 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000000005858 102.0
PYH2_k127_3146010_2 DNA polymerase III - - - 0.00000000000000000002274 101.0
PYH2_k127_3146010_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000005189 91.0
PYH2_k127_3146010_4 SpoVT / AbrB like domain - - - 0.0000000001722 64.0
PYH2_k127_3146010_5 AAA ATPase domain - - - 0.0000004287 53.0
PYH2_k127_3157902_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1364.0
PYH2_k127_3157902_1 Carboxypeptidase regulatory-like domain - - - 0.0 1026.0
PYH2_k127_3157902_10 Belongs to the LDH2 MDH2 oxidoreductase family K08092 - 1.1.1.130 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003866 401.0
PYH2_k127_3157902_11 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 385.0
PYH2_k127_3157902_12 pfkB family carbohydrate kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 379.0
PYH2_k127_3157902_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 309.0
PYH2_k127_3157902_14 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003394 299.0
PYH2_k127_3157902_15 Methane oxygenase PmoA - - - 0.0000000000000000000000000000000000000000000000000000000000005478 222.0
PYH2_k127_3157902_16 SIS domain K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000001103 214.0
PYH2_k127_3157902_17 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000003857 211.0
PYH2_k127_3157902_2 Cytochrome c554 and c-prime - - - 3.555e-285 898.0
PYH2_k127_3157902_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 5.222e-276 852.0
PYH2_k127_3157902_4 phosphoglucosamine mutase activity K00971,K01840 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.7.13,5.4.2.8 4.431e-241 758.0
PYH2_k127_3157902_5 Sulfatase - - - 1.993e-214 683.0
PYH2_k127_3157902_6 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 559.0
PYH2_k127_3157902_7 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 504.0
PYH2_k127_3157902_8 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007411 488.0
PYH2_k127_3157902_9 Hypothetical methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 424.0
PYH2_k127_3172306_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 1.881e-200 656.0
PYH2_k127_3172306_1 SMP-30/Gluconolaconase/LRE-like region - - - 0.0000000000000000000000000000000000000000000000000000002652 200.0
PYH2_k127_318020_0 Nitrilase cyanide hydratase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001363 277.0
PYH2_k127_318020_1 - - - - 0.0000000000000000000000000000000000000000000000000000007285 196.0
PYH2_k127_318020_2 SMART Chromosomal replication initiator DnaA domain - - - 0.00000000000000000000000000000000000000000000000000003751 189.0
PYH2_k127_318020_3 SMART Chromosomal replication initiator DnaA domain - - - 0.0000000000000000000000000000000000003731 145.0
PYH2_k127_318020_4 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain K02479,K07692 - - 0.0000000000000007214 83.0
PYH2_k127_318020_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0004857 43.0
PYH2_k127_3180586_0 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.00000000000000000000000000000000000000000000000000000000000000003545 230.0
PYH2_k127_3180586_1 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672,K10794 - 1.21.4.1,1.21.4.2 0.00000000000000001749 89.0
PYH2_k127_3190463_0 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 599.0
PYH2_k127_3190463_1 PFAM Nucleotidyl transferase K00971,K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007127 284.0
PYH2_k127_3190463_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000005244 241.0
PYH2_k127_3190463_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000001619 128.0
PYH2_k127_3190463_4 TonB dependent receptor K16087 - - 0.000000000000000000000000007558 129.0
PYH2_k127_3190463_5 Alpha/beta hydrolase family - - - 0.0000000000000000000005739 109.0
PYH2_k127_3190463_6 Belongs to the sigma-70 factor family. ECF subfamily K03088 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0006970,GO:0008150,GO:0009266,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000000197 69.0
PYH2_k127_320027_0 beta-fructofuranosidase activity - - - 0.0000000000000000000001689 112.0
PYH2_k127_320027_1 6-phosphogluconolactonase activity - - - 0.000007002 59.0
PYH2_k127_32063_0 Belongs to the HpcH HpaI aldolase family - - - 0.0000000000000000002048 88.0
PYH2_k127_3241040_0 Belongs to the 'phage' integrase family K14059 - - 0.00000000000000000000000000000000000000000014 170.0
PYH2_k127_3241040_1 VRR-NUC domain - - - 0.000000000000000000000000000002652 124.0
PYH2_k127_3241040_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000003225 82.0
PYH2_k127_3241040_3 transcriptional regulator K07726 - - 0.0000000003086 66.0
PYH2_k127_325164_0 Alpha-L-fucosidase K01206 - 3.2.1.51 1.501e-210 666.0
PYH2_k127_325164_1 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 503.0
PYH2_k127_325164_10 protein modification by small protein conjugation - GO:0000151,GO:0005575,GO:0005622,GO:0005623,GO:0031461,GO:0031463,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1990234 - 0.0006689 46.0
PYH2_k127_325164_2 Part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K02008 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007531 271.0
PYH2_k127_325164_3 PFAM cobalamin (vitamin B12) biosynthesis CbiM K02007 - - 0.000000000000000000000000000000000000000000000000001301 196.0
PYH2_k127_325164_4 hydrolase of the alpha beta K07018 - - 0.00000000000000000000000000000000000000000000000001219 188.0
PYH2_k127_325164_5 Integral membrane protein - - - 0.000000000000000000000000000000000000003452 155.0
PYH2_k127_325164_6 TIGRFAM cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.00000000000000000000000000003866 125.0
PYH2_k127_325164_7 ATP-binding region, ATPase domain protein domain protein K01338,K13587 - 2.7.13.3,3.4.21.53 0.00000000000000000000000000006884 119.0
PYH2_k127_325164_8 Metallo-beta-lactamase superfamily - - - 0.000000000000006932 86.0
PYH2_k127_325164_9 ubiE/COQ5 methyltransferase family - - - 0.000001278 59.0
PYH2_k127_3273828_0 - - - - 1.086e-291 914.0
PYH2_k127_3273828_1 PFAM oxidoreductase domain protein - - - 6.032e-200 632.0
PYH2_k127_3273828_2 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 334.0
PYH2_k127_3273828_3 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000001006 228.0
PYH2_k127_3273828_4 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000002304 188.0
PYH2_k127_3273828_5 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000001862 162.0
PYH2_k127_3273828_6 Zincin-like metallopeptidase - - - 0.000000000000000005171 89.0
PYH2_k127_3273828_7 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000008374 84.0
PYH2_k127_3273828_8 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000005797 60.0
PYH2_k127_3283159_0 Transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 538.0
PYH2_k127_3285577_0 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006522 512.0
PYH2_k127_3285577_1 RNA-DNA hybrid ribonuclease activity K03469,K06864,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000002021 214.0
PYH2_k127_3285577_2 serine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000008406 198.0
PYH2_k127_3295371_0 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 494.0
PYH2_k127_3295371_1 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000915 428.0
PYH2_k127_3295371_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 404.0
PYH2_k127_3295371_3 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 302.0
PYH2_k127_3295371_4 PFAM ATP-binding region ATPase domain protein - - - 0.00000000000000000000000000000000000000000000009956 190.0
PYH2_k127_3295371_5 Cytochrome c K00413 - - 0.000000000000000000000000000000000005588 147.0
PYH2_k127_3295371_6 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000000000000000005043 117.0
PYH2_k127_3295371_7 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.00000002801 60.0
PYH2_k127_3298505_0 oxoglutarate dehydrogenase (succinyl-transferring) activity K00164,K01616 GO:0000287,GO:0003674,GO:0003824,GO:0004591,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006103,GO:0008150,GO:0008152,GO:0008683,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016624,GO:0016740,GO:0016744,GO:0016829,GO:0016830,GO:0016831,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0019842,GO:0022900,GO:0030312,GO:0030976,GO:0032991,GO:0036094,GO:0040007,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0045333,GO:0046872,GO:0048037,GO:0050439,GO:0050662,GO:0051186,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363,GO:1901681,GO:1902494,GO:1990204,GO:1990234 1.2.4.2,4.1.1.71 0.0 1349.0
PYH2_k127_3298505_1 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 453.0
PYH2_k127_3298505_10 Phosphoesterase family K01114 - 3.1.4.3 0.00002536 53.0
PYH2_k127_3298505_2 TIGRFAM RHS repeat-associated core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003312 291.0
PYH2_k127_3298505_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000003092 194.0
PYH2_k127_3298505_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000001525 181.0
PYH2_k127_3298505_5 - - - - 0.000000000000000000002303 96.0
PYH2_k127_3298505_6 von Willebrand factor (vWF) type A domain - - - 0.0000000000000007474 89.0
PYH2_k127_3298505_7 rhs family - - - 0.000000000001145 82.0
PYH2_k127_3298505_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05889,K12678 - 1.1.2.6 0.0000000006498 73.0
PYH2_k127_3298505_9 snoRNA binding - - - 0.0000009202 58.0
PYH2_k127_3316318_0 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000009898 177.0
PYH2_k127_3316318_1 Peptidase family M50 K06402 - - 0.0000000004524 64.0
PYH2_k127_3316318_2 BON domain - - - 0.0000001454 56.0
PYH2_k127_3343388_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 604.0
PYH2_k127_3343388_1 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 292.0
PYH2_k127_3343388_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000001478 261.0
PYH2_k127_3343388_3 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000009009 170.0
PYH2_k127_3343388_4 - - - - 0.0000000000000000000000000000000004239 147.0
PYH2_k127_3343388_5 PFAM Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000003248 136.0
PYH2_k127_3345437_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 613.0
PYH2_k127_3345437_1 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 574.0
PYH2_k127_3351100_0 extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000001505 208.0
PYH2_k127_3351100_1 AAA ATPase domain - - - 0.000000000000000000000000000000000000000000000000000003659 218.0
PYH2_k127_3354593_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1970.0
PYH2_k127_3354593_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 GO:0000428,GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0 1263.0
PYH2_k127_3354593_2 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000002695 124.0
PYH2_k127_3373060_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000004368 209.0
PYH2_k127_3373060_1 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.00000000000000000000000000000000000000000000000003987 182.0
PYH2_k127_3373060_2 radical SAM K06871 - - 0.000000000000000002453 87.0
PYH2_k127_3373060_3 radical SAM K06871 - - 0.000000000002675 70.0
PYH2_k127_3438799_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 376.0
PYH2_k127_3438799_1 Integrase core domain - - - 0.00000000000000000000000000000000000001443 149.0
PYH2_k127_3455246_0 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000002707 205.0
PYH2_k127_3455246_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000001077 81.0
PYH2_k127_3459558_0 Converts the aldose L-fucose into the corresponding ketose L-fuculose K01818 - 5.3.1.25,5.3.1.3 9.089e-308 951.0
PYH2_k127_3459558_1 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 527.0
PYH2_k127_3459558_10 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000008375 214.0
PYH2_k127_3459558_11 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000001217 178.0
PYH2_k127_3459558_12 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000002595 133.0
PYH2_k127_3459558_13 FhlB domain-containing protein K04061 - - 0.0000000000000000000000003388 109.0
PYH2_k127_3459558_14 Smr domain - - - 0.0000000000000000000000008892 109.0
PYH2_k127_3459558_2 Psort location Cytoplasmic, score K00848,K00879 - 2.7.1.5,2.7.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 532.0
PYH2_k127_3459558_3 carbohydrate kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007313 529.0
PYH2_k127_3459558_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009461 469.0
PYH2_k127_3459558_5 belongs to the nudix hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 378.0
PYH2_k127_3459558_6 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 357.0
PYH2_k127_3459558_7 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 386.0
PYH2_k127_3459558_8 Nicotinate-nucleotide pyrophosphorylase carboxylating K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 339.0
PYH2_k127_3459558_9 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001474 271.0
PYH2_k127_3474174_0 iron-nicotianamine transmembrane transporter activity - GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0008150,GO:0016020,GO:0022857,GO:0051179,GO:0051234,GO:0055085 - 5.131e-292 911.0
PYH2_k127_3474174_1 TIGRFAM aminoacyl-histidine dipeptidase K01270 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 586.0
PYH2_k127_3474174_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004949 556.0
PYH2_k127_3474174_3 import. Responsible for energy coupling to the transport system K10441 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0008643,GO:0015144,GO:0015145,GO:0015146,GO:0015399,GO:0015405,GO:0015407,GO:0015591,GO:0015608,GO:0015611,GO:0015749,GO:0015750,GO:0015752,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034219,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0043167,GO:0043168,GO:0043211,GO:0043492,GO:0051119,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0097159,GO:0097367,GO:1901265,GO:1901363 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 458.0
PYH2_k127_3474174_4 GHMP kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 440.0
PYH2_k127_3474174_5 Branched-chain amino acid transport system / permease component K10440 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 307.0
PYH2_k127_3474174_6 ornithine cyclodeaminase mu-crystallin K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002552 283.0
PYH2_k127_3474174_7 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000006986 239.0
PYH2_k127_3474174_8 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000006302 172.0
PYH2_k127_3474174_9 - - - - 0.000000000000000000000000002039 127.0
PYH2_k127_3483750_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004581 343.0
PYH2_k127_3483750_1 peptidase activity, acting on L-amino acid peptides - - - 0.0009593 44.0
PYH2_k127_3495739_0 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.000000000000000000007427 103.0
PYH2_k127_3495739_1 Protein of unknown function (DUF2934) - - - 0.000001114 55.0
PYH2_k127_3495739_2 metallopeptidase activity K02280 - - 0.0002948 47.0
PYH2_k127_3495739_3 O-methyltransferase activity - - - 0.0007619 44.0
PYH2_k127_3497903_0 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 387.0
PYH2_k127_3497903_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 300.0
PYH2_k127_3497903_2 Rhs Element Vgr Protein K11904 - - 0.000000000000000000000000000000005403 140.0
PYH2_k127_3497903_3 - - - - 0.00000000000004796 83.0
PYH2_k127_3497903_4 Cysteine-rich domain K00113 - 1.1.5.3 0.000108 48.0
PYH2_k127_3504211_0 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 458.0
PYH2_k127_3504211_1 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000000000000000000009566 233.0
PYH2_k127_350518_0 Pyridoxal-phosphate dependent enzyme K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 540.0
PYH2_k127_350518_1 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.0000000000000000000000000000000000000000000000000000001206 198.0
PYH2_k127_350518_2 Transcriptional regulator IclR - - - 0.000000000000000000000000000000000000000000000000002513 191.0
PYH2_k127_350518_3 OST-HTH/LOTUS domain - - - 0.0000000000005376 74.0
PYH2_k127_350518_4 Belongs to the SOS response-associated peptidase family - - - 0.000000000002747 70.0
PYH2_k127_3515916_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.075e-207 660.0
PYH2_k127_3515916_1 Trehalose utilisation K09992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 396.0
PYH2_k127_3515916_2 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009334 403.0
PYH2_k127_3515916_3 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000001347 140.0
PYH2_k127_3515916_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000001182 91.0
PYH2_k127_3515916_5 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.0000000108 56.0
PYH2_k127_3556187_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 405.0
PYH2_k127_3556187_1 Belongs to the MlaE permease family K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004158 269.0
PYH2_k127_3556187_2 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006708 245.0
PYH2_k127_3556187_3 MlaD protein K02067 - - 0.000000001482 66.0
PYH2_k127_3565292_0 Two component, sigma54 specific, transcriptional regulator, Fis family K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 428.0
PYH2_k127_3565292_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 311.0
PYH2_k127_3565292_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000000000000000000000002905 127.0
PYH2_k127_3568656_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001261 260.0
PYH2_k127_3568656_1 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000621 65.0
PYH2_k127_35701_0 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 312.0
PYH2_k127_35701_1 Alpha/beta hydrolase family - - - 0.00000001421 61.0
PYH2_k127_3574063_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004886 269.0
PYH2_k127_3574063_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000005703 241.0
PYH2_k127_3574063_2 Transposase K07484,K20444 - - 0.00000000000000000007021 96.0
PYH2_k127_3574063_3 PFAM Glycosyl transferase, group 1 - - - 0.000000001032 64.0
PYH2_k127_3598499_0 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006257 291.0
PYH2_k127_3598499_1 hydrolase, family 65, central catalytic - - - 0.0000001996 56.0
PYH2_k127_3619211_0 GTP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 413.0
PYH2_k127_3619211_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000111 211.0
PYH2_k127_3620579_0 Protein of unknown function DUF86 - - - 0.0000000000000000000000000006349 116.0
PYH2_k127_3620579_1 Large extracellular alpha-helical protein - - - 0.0000000000000000000000007471 120.0
PYH2_k127_3620579_2 Domain of unknown function (DUF1998) - - - 0.0000000000000000000001548 97.0
PYH2_k127_3620579_3 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000008901 98.0
PYH2_k127_3621168_0 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 3.18e-221 707.0
PYH2_k127_3621168_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 379.0
PYH2_k127_3621168_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 368.0
PYH2_k127_3621168_4 - - - - 0.0000000007716 68.0
PYH2_k127_3627607_0 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005577 295.0
PYH2_k127_3627607_1 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000003314 126.0
PYH2_k127_3632709_0 TonB dependent receptor K16090 - - 3.032e-232 743.0
PYH2_k127_3632709_1 belongs to the Fur family K03711,K09823,K09825 - - 0.000000000000000000000000000000000000000000000008927 177.0
PYH2_k127_3632709_2 2TM domain - - - 0.000000000884 70.0
PYH2_k127_3632709_3 PFAM Sodium calcium exchanger membrane region K07301 - - 0.0001088 45.0
PYH2_k127_3633888_0 Belongs to the peptidase S16 family - - - 1.181e-256 817.0
PYH2_k127_3633888_1 phosphoenolpyruvate carboxykinase (ATP) activity K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 9.527e-235 734.0
PYH2_k127_3633888_2 Aminotransferase K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 586.0
PYH2_k127_3633888_3 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 310.0
PYH2_k127_3633888_4 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000002269 235.0
PYH2_k127_3633888_5 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000005595 160.0
PYH2_k127_3642827_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 6.592e-202 649.0
PYH2_k127_3661861_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.816e-221 698.0
PYH2_k127_3661861_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 624.0
PYH2_k127_3661861_2 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000033 379.0
PYH2_k127_3661861_3 Cobalamin B12-binding K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000002357 199.0
PYH2_k127_3661861_4 BON domain - - - 0.00000000000000000000000000000000000000000000000496 178.0
PYH2_k127_3661861_5 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000002711 153.0
PYH2_k127_3661861_7 Putative heavy-metal-binding - - - 0.000000000000000000000000000001382 126.0
PYH2_k127_3661861_8 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000001943 124.0
PYH2_k127_3661861_9 Putative zinc-finger - - - 0.0002115 50.0
PYH2_k127_3668422_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 436.0
PYH2_k127_3668422_1 Trehalose utilisation K09992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 324.0
PYH2_k127_3668422_2 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001495 273.0
PYH2_k127_3668422_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000009395 239.0
PYH2_k127_3668422_4 Yqey-like protein K09117 - - 0.00000000000000000000000000000000000000000000000000002423 192.0
PYH2_k127_3668422_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000001159 78.0
PYH2_k127_3721701_0 FAD dependent oxidoreductase - - - 4.435e-251 791.0
PYH2_k127_3721701_1 helix_turn_helix, arabinose operon control protein K02529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 317.0
PYH2_k127_3721701_2 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 308.0
PYH2_k127_3721701_3 Belongs to the thiolase family K07508 - 2.3.1.16 0.000000000000000001267 89.0
PYH2_k127_3727551_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 372.0
PYH2_k127_3727551_1 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000001177 72.0
PYH2_k127_3727551_2 Putative mono-oxygenase ydhR - - - 0.0006651 43.0
PYH2_k127_3739243_0 elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 506.0
PYH2_k127_3739243_1 SRP54-type protein, GTPase domain K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 491.0
PYH2_k127_3739243_10 Oxidoreductase NAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000000000000006391 194.0
PYH2_k127_3739243_11 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000008444 160.0
PYH2_k127_3739243_12 - - - - 0.00000000000000000000000000000000000000001984 171.0
PYH2_k127_3739243_13 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000626 126.0
PYH2_k127_3739243_14 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000004056 117.0
PYH2_k127_3739243_15 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000001267 113.0
PYH2_k127_3739243_16 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000001083 105.0
PYH2_k127_3739243_17 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000414 61.0
PYH2_k127_3739243_18 - - - - 0.00000004055 62.0
PYH2_k127_3739243_19 - - - - 0.000004213 55.0
PYH2_k127_3739243_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 475.0
PYH2_k127_3739243_20 Transglycosylase SLT domain K08309 - - 0.00005153 47.0
PYH2_k127_3739243_3 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 395.0
PYH2_k127_3739243_4 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 353.0
PYH2_k127_3739243_5 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002796 276.0
PYH2_k127_3739243_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000001699 214.0
PYH2_k127_3739243_7 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001993 214.0
PYH2_k127_3739243_8 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000000005143 229.0
PYH2_k127_3739243_9 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000003485 200.0
PYH2_k127_3767443_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 479.0
PYH2_k127_3767443_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 341.0
PYH2_k127_3767443_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595,K06883 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002214 285.0
PYH2_k127_3767443_3 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001465 274.0
PYH2_k127_3767443_4 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000454 213.0
PYH2_k127_3767443_5 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000008438 198.0
PYH2_k127_3767443_6 FecR protein - - - 0.0000000000000000000000000000000000000000000000000001477 210.0
PYH2_k127_3767443_7 TIGRFAM capsular exopolysaccharide family - - - 0.00000000000000000000000000000005005 136.0
PYH2_k127_3767443_8 Domain of unknown function (DUF362) - - - 0.00000000000000000000000001006 112.0
PYH2_k127_3767443_9 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0000009622 53.0
PYH2_k127_3778701_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 434.0
PYH2_k127_3778701_1 Beta-L-arabinofuranosidase, GH127 - - - 0.00000000000000000000000000000000000000204 168.0
PYH2_k127_3780939_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 392.0
PYH2_k127_3780939_1 ROK family - - - 0.000000000000000000000000000000000000000000000000000000000000000000196 245.0
PYH2_k127_3783369_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004818 363.0
PYH2_k127_3783369_1 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000001999 164.0
PYH2_k127_3804043_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003466 286.0
PYH2_k127_3804043_1 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000003506 256.0
PYH2_k127_3804043_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000001068 192.0
PYH2_k127_3804043_3 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000002858 147.0
PYH2_k127_3804043_4 GYD domain - - - 0.000000000000000000000000000005283 121.0
PYH2_k127_3804043_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000236 89.0
PYH2_k127_380949_0 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004399 262.0
PYH2_k127_380949_1 Phage integrase family - - - 0.00000000000000001104 95.0
PYH2_k127_380949_2 Integrase catalytic K07497 - - 0.0000000000000001237 81.0
PYH2_k127_380949_3 - - - - 0.000002293 52.0
PYH2_k127_381433_0 - K07283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 311.0
PYH2_k127_381433_1 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 288.0
PYH2_k127_381433_2 Protein tyrosine kinase - - - 0.0000001552 59.0
PYH2_k127_382921_0 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000002037 197.0
PYH2_k127_382921_1 protein containing a NRPS condensation (Elongation) domain - - - 0.0000000000000000000000000000000000000000000000004195 194.0
PYH2_k127_382921_2 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000001361 179.0
PYH2_k127_382921_3 23S rRNA-intervening sequence protein - - - 0.000000259 55.0
PYH2_k127_3830787_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000002244 76.0
PYH2_k127_3830787_1 BlaR1 peptidase M56 - - - 0.00000000004031 74.0
PYH2_k127_3832202_0 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002223 328.0
PYH2_k127_3832202_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 292.0
PYH2_k127_3832202_2 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003096 285.0
PYH2_k127_3832202_3 Conserved hypothetical protein (DUF2461) - - - 0.000000000000000000000000000000000000000000000000000000001489 209.0
PYH2_k127_3832202_4 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000002374 187.0
PYH2_k127_3832202_5 pyrroloquinoline quinone binding K01206 - 3.2.1.51 0.000000001215 66.0
PYH2_k127_3838329_0 membrane protein, TerC K05794 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 404.0
PYH2_k127_3838329_1 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009588 389.0
PYH2_k127_3838329_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000002456 248.0
PYH2_k127_3838329_3 - - - - 0.000000000000000000000000000000000000000000000000000007879 205.0
PYH2_k127_3838329_4 Catalyzes activation of the choline trimethylamine-lyase CutC under anaerobic conditions by generation of an organic free radical on a glycine residue, via K20037 GO:0001505,GO:0003674,GO:0003824,GO:0005488,GO:0006576,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009308,GO:0009310,GO:0009987,GO:0016491,GO:0019695,GO:0034641,GO:0042133,GO:0042135,GO:0042402,GO:0042426,GO:0043364,GO:0044106,GO:0044237,GO:0044248,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0065007,GO:0065008,GO:0070283,GO:0071704,GO:0097164,GO:1901564,GO:1901565,GO:1901575 - 0.00000002972 57.0
PYH2_k127_3846081_0 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 472.0
PYH2_k127_3846081_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000003234 83.0
PYH2_k127_3846081_2 nuclease activity - - - 0.000000001551 61.0
PYH2_k127_3846081_3 nucleotidyltransferase activity K07061 - - 0.0000005819 55.0
PYH2_k127_3847056_0 Aldo Keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003478 359.0
PYH2_k127_3847056_1 PFAM AAA ATPase central domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002482 261.0
PYH2_k127_3847056_10 PFAM FHA domain - - - 0.00000009738 65.0
PYH2_k127_3847056_11 Latent-transforming growth factor beta-binding protein 1 K19559 GO:0001527,GO:0001568,GO:0001944,GO:0003205,GO:0003231,GO:0003279,GO:0003281,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004675,GO:0004888,GO:0005024,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005615,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005783,GO:0005788,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007275,GO:0007507,GO:0007584,GO:0008104,GO:0008150,GO:0008152,GO:0009605,GO:0009611,GO:0009612,GO:0009628,GO:0009719,GO:0009725,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009968,GO:0009987,GO:0009991,GO:0010033,GO:0010646,GO:0010648,GO:0010712,GO:0010714,GO:0012505,GO:0014070,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017015,GO:0019199,GO:0019222,GO:0019538,GO:0019838,GO:0019955,GO:0023051,GO:0023052,GO:0023057,GO:0030425,GO:0030512,GO:0031012,GO:0031667,GO:0031668,GO:0031669,GO:0031670,GO:0031974,GO:0032501,GO:0032502,GO:0032870,GO:0032965,GO:0032967,GO:0032991,GO:0033036,GO:0033273,GO:0033280,GO:0033993,GO:0035581,GO:0035583,GO:0035904,GO:0036119,GO:0036120,GO:0036211,GO:0036477,GO:0038023,GO:0038045,GO:0042060,GO:0042221,GO:0042995,GO:0043005,GO:0043025,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044297,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044463,GO:0044464,GO:0045185,GO:0048471,GO:0048513,GO:0048518,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048731,GO:0048856,GO:0050431,GO:0050436,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051235,GO:0051716,GO:0060089,GO:0060840,GO:0060976,GO:0065007,GO:0065008,GO:0070013,GO:0070848,GO:0070887,GO:0071107,GO:0071214,GO:0071260,GO:0071295,GO:0071305,GO:0071310,GO:0071363,GO:0071374,GO:0071396,GO:0071407,GO:0071495,GO:0071496,GO:0071559,GO:0071560,GO:0071692,GO:0071694,GO:0071704,GO:0072358,GO:0072359,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0097447,GO:0097458,GO:0099080,GO:0099081,GO:0099512,GO:0104004,GO:0120025,GO:0120038,GO:0140096,GO:1900115,GO:1900116,GO:1901564,GO:1901700,GO:1901701,GO:1903844,GO:1903845 - 0.000741 49.0
PYH2_k127_3847056_2 Cell division protein 48, CDC48, domain 2 K13525 - - 0.00000000000000000000000000000000000000000000000000003214 202.0
PYH2_k127_3847056_3 - - - - 0.00000000000000000000000000000000000000000000000004082 203.0
PYH2_k127_3847056_4 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.00000000000000000000000000000000000000000000005751 191.0
PYH2_k127_3847056_5 serine threonine protein kinase K08884,K12132 GO:0002237,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005539,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009617,GO:0009719,GO:0009847,GO:0009987,GO:0010033,GO:0010243,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0023052,GO:0032494,GO:0032502,GO:0036211,GO:0042221,GO:0042834,GO:0043170,GO:0043207,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051704,GO:0051707,GO:0051716,GO:0065007,GO:0070887,GO:0071216,GO:0071219,GO:0071224,GO:0071310,GO:0071417,GO:0071495,GO:0071704,GO:0071944,GO:0097367,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701 2.7.11.1 0.000000000000000000000000000000000000000000001556 188.0
PYH2_k127_3847056_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000006884 164.0
PYH2_k127_3847056_7 AAA domain - - - 0.0000000000000000000000000000000000000000003733 175.0
PYH2_k127_3847056_8 PA domain - - - 0.0000000000000000000000000000000000000008031 171.0
PYH2_k127_3847056_9 - - - - 0.0000000000127 73.0
PYH2_k127_3852375_0 lactate metabolic process - - - 2.341e-223 711.0
PYH2_k127_3852375_1 amino acid - - - 1.723e-214 676.0
PYH2_k127_3852375_10 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000001319 236.0
PYH2_k127_3852375_11 FCD - - - 0.000000000000000000000000000000000000000000000001108 182.0
PYH2_k127_3852375_12 MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000002608 176.0
PYH2_k127_3852375_13 methylmalonyl-CoA K01849 - 5.4.99.2 0.000000000000000000000000000000000008657 143.0
PYH2_k127_3852375_14 Amidohydrolase family - - - 0.0000000000000000001013 102.0
PYH2_k127_3852375_15 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000001824 73.0
PYH2_k127_3852375_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002973 596.0
PYH2_k127_3852375_3 Methylmalonyl-CoA mutase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009832 480.0
PYH2_k127_3852375_4 Catalyzes the aminotransferase reaction from putrescine to 2-oxoglutarate, leading to glutamate and 4-aminobutanal, which spontaneously cyclizes to form 1-pyrroline. Is also able to transaminate cadaverine and, in lower extent, spermidine, but not ornithine K00819,K09251,K21778 - 2.6.1.13,2.6.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 416.0
PYH2_k127_3852375_5 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002197 374.0
PYH2_k127_3852375_6 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002399 372.0
PYH2_k127_3852375_7 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 353.0
PYH2_k127_3852375_8 transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 353.0
PYH2_k127_3852375_9 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000001851 247.0
PYH2_k127_3864532_0 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 496.0
PYH2_k127_3864532_1 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004083 278.0
PYH2_k127_3864532_2 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000001567 197.0
PYH2_k127_3864532_3 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000002304 131.0
PYH2_k127_3864532_4 - - - - 0.00000000000000000000001076 102.0
PYH2_k127_3864532_5 Domain of unknown function (DUF4258) - - - 0.000003484 53.0
PYH2_k127_3874205_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009872 407.0
PYH2_k127_3874205_1 phage integrase family K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000111 225.0
PYH2_k127_389019_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 456.0
PYH2_k127_389019_1 conserved protein (DUF2088) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 402.0
PYH2_k127_389019_2 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 315.0
PYH2_k127_389019_3 histone H2A-K13 ubiquitination K01338,K07157 - 3.4.21.53 0.00000000000000000000000000000000114 138.0
PYH2_k127_3892331_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000395 258.0
PYH2_k127_3892331_2 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000000000004626 125.0
PYH2_k127_3892331_3 - - - - 0.0000000000000044 82.0
PYH2_k127_3892331_4 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000004807 51.0
PYH2_k127_3902253_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000187 169.0
PYH2_k127_3902253_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.0000000000000000000000000000000000000000000024 167.0
PYH2_k127_3902253_10 nucleotidyltransferase activity K07076 - - 0.0000001717 58.0
PYH2_k127_3902253_2 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000005552 138.0
PYH2_k127_3902253_3 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000001307 109.0
PYH2_k127_3902253_4 Radical SAM domain protein - - - 0.000000000000000000000003594 108.0
PYH2_k127_3902253_5 Protein of unknown function (DUF2283) - - - 0.00000000000000000000001477 101.0
PYH2_k127_3902253_6 - - - - 0.00000000000000000002025 93.0
PYH2_k127_3902253_7 - - - - 0.0000000000000000009435 88.0
PYH2_k127_3902253_8 signal peptide processing K13280 - 3.4.21.89 0.00000000005943 69.0
PYH2_k127_3902253_9 nucleotidyltransferase activity K07076 - - 0.0000000001314 67.0
PYH2_k127_39144_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 588.0
PYH2_k127_392317_0 FR47-like protein - - - 0.000000000000000000000000000008807 129.0
PYH2_k127_392317_1 Domain of unknown function (DUF4332) - - - 0.000000121 62.0
PYH2_k127_3924723_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.163e-219 696.0
PYH2_k127_3924723_1 (ABC) transporter K06147,K18890 - - 3.07e-201 644.0
PYH2_k127_3924723_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000001581 156.0
PYH2_k127_3924723_11 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K21062 - 3.5.4.22 0.00000000000000000000001558 104.0
PYH2_k127_3924723_12 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000001952 107.0
PYH2_k127_3924723_13 - - - - 0.00000000000000003563 88.0
PYH2_k127_3924723_14 protein import - - - 0.000000000001723 81.0
PYH2_k127_3924723_15 Ribosomal protein L35 K02916 - - 0.0000000004359 68.0
PYH2_k127_3924723_16 Belongs to the BshC family K22136 - - 0.000000008321 68.0
PYH2_k127_3924723_17 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000004236 59.0
PYH2_k127_3924723_2 ABC transporter, transmembrane K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 568.0
PYH2_k127_3924723_3 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 477.0
PYH2_k127_3924723_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 372.0
PYH2_k127_3924723_5 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 307.0
PYH2_k127_3924723_6 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000002496 241.0
PYH2_k127_3924723_7 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000678 235.0
PYH2_k127_3924723_8 N-acetylglucosaminylinositol deacetylase activity K01463 - - 0.0000000000000000000000000000000000000000000000000000002249 202.0
PYH2_k127_3924723_9 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000000001502 188.0
PYH2_k127_3926410_0 beta-N-acetylhexosaminidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 486.0
PYH2_k127_3926410_1 Major Facilitator Superfamily K02445,K07783 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008506 421.0
PYH2_k127_3926410_2 COGs COG0673 dehydrogenase and related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 413.0
PYH2_k127_3926410_3 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 342.0
PYH2_k127_3926410_4 transmembrane transporter activity K08225 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002591 257.0
PYH2_k127_3926410_5 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000006587 216.0
PYH2_k127_3960935_0 Peptidase family C69 K14358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 308.0
PYH2_k127_3960935_1 PFAM Integrase catalytic - - - 0.00000000000000000000000000000001792 130.0
PYH2_k127_3960935_2 Integrase core domain - - - 0.0000000000000000000000000000004435 125.0
PYH2_k127_3960935_3 Integrase core domain - - - 0.0000000000000000001679 90.0
PYH2_k127_3960935_4 Integrase core domain - - - 0.00000000000000005249 82.0
PYH2_k127_3977395_0 Pyruvate phosphate dikinase, PEP/pyruvate binding domain - - - 6.903e-244 776.0
PYH2_k127_3977395_1 amine oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 411.0
PYH2_k127_3977395_2 diaminopimelate decarboxylase activity K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000001451 234.0
PYH2_k127_3977395_3 coenzyme F420 binding K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000003348 177.0
PYH2_k127_3978475_0 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 433.0
PYH2_k127_3978475_1 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 359.0
PYH2_k127_3978475_2 Two component transcriptional regulator, winged helix family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 345.0
PYH2_k127_3978475_3 Higher Eukarytoes and Prokaryotes Nucleotide-binding domain - - - 0.0000000000000004459 80.0
PYH2_k127_3991496_0 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 367.0
PYH2_k127_3991496_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000002173 169.0
PYH2_k127_3991496_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000001053 147.0
PYH2_k127_3991496_3 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.0000000000000000000000000000002747 128.0
PYH2_k127_3991496_4 Trm112p-like protein K09791 - - 0.0000000000000000000006462 99.0
PYH2_k127_3991496_5 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000007158 74.0
PYH2_k127_3991496_6 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000493 62.0
PYH2_k127_3991496_7 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0001028 45.0
PYH2_k127_4019145_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 421.0
PYH2_k127_4019145_1 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002853 281.0
PYH2_k127_4019145_10 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000001945 174.0
PYH2_k127_4019145_11 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000002639 109.0
PYH2_k127_4019145_12 PFAM SNARE associated Golgi protein - - - 0.00000000000000000000003503 106.0
PYH2_k127_4019145_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000006273 100.0
PYH2_k127_4019145_14 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.00000000000001166 78.0
PYH2_k127_4019145_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002263 275.0
PYH2_k127_4019145_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005611 253.0
PYH2_k127_4019145_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000002718 244.0
PYH2_k127_4019145_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000007874 252.0
PYH2_k127_4019145_6 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000289 232.0
PYH2_k127_4019145_7 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000006219 225.0
PYH2_k127_4019145_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000354 204.0
PYH2_k127_4019145_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000002842 177.0
PYH2_k127_4029513_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008024 278.0
PYH2_k127_4029513_1 Oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005561 262.0
PYH2_k127_4029513_2 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000000000000000000000000004225 222.0
PYH2_k127_4029513_3 TonB C terminal - - - 0.00000000003298 75.0
PYH2_k127_4030368_0 PFAM UDP-glucose GDP-mannose dehydrogenase K02474,K13015 - 1.1.1.136 0.0000000000000000000000000000000000000004828 149.0
PYH2_k127_4030368_1 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000003375 117.0
PYH2_k127_4041555_0 radical SAM domain protein K22318 - - 2.989e-225 711.0
PYH2_k127_4041555_1 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000007733 160.0
PYH2_k127_4041555_2 Uracil-DNA glycosylase - - - 0.00000000000005173 75.0
PYH2_k127_4041731_0 Magnesium transport protein CorA K03284 - - 4.317e-203 646.0
PYH2_k127_4041731_1 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009154 382.0
PYH2_k127_4041731_10 DNA-binding transcription factor activity - - - 0.000000000000000000000000004915 115.0
PYH2_k127_4041731_11 ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component - - - 0.0000000000000000000000006036 112.0
PYH2_k127_4041731_12 Enoyl-CoA hydratase/isomerase K13238 - 5.3.3.8 0.000000000000000000000002893 112.0
PYH2_k127_4041731_13 AhpC Tsa family K03564 - 1.11.1.15 0.0000000000000000000007121 98.0
PYH2_k127_4041731_14 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000003233 65.0
PYH2_k127_4041731_2 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006519 307.0
PYH2_k127_4041731_3 Xylose isomerase-like TIM barrel K03079 - 5.1.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000231 269.0
PYH2_k127_4041731_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006169 271.0
PYH2_k127_4041731_5 PFAM Aminotransferase class I and II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 254.0
PYH2_k127_4041731_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000231 240.0
PYH2_k127_4041731_7 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000001512 203.0
PYH2_k127_4041731_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000003181 144.0
PYH2_k127_4041731_9 protein TIM barrel - - - 0.0000000000000000000000000000000197 141.0
PYH2_k127_4054261_0 pyrroline-5-carboxylate reductase activity K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 310.0
PYH2_k127_4054261_1 Part of a complex that catalyzes the formation of methyl-coenzyme M and tetrahydromethanopterin from coenzyme M and methyl-tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step K00577 - 2.1.1.86 0.00000000000000000000000000000000000000000000000000000000000000000000006409 251.0
PYH2_k127_4054261_10 Thioredoxin domain - - - 0.0000000000000000000001105 99.0
PYH2_k127_4054261_11 DGC domain - - - 0.0000000000000000000003731 103.0
PYH2_k127_4054261_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000009273 92.0
PYH2_k127_4054261_13 Extracellular solute-binding protein family 3 K07679 - 2.7.13.3 0.000000000000006146 78.0
PYH2_k127_4054261_14 - - - - 0.0000000000001323 76.0
PYH2_k127_4054261_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000001888 71.0
PYH2_k127_4054261_16 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000001494 70.0
PYH2_k127_4054261_2 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000002769 225.0
PYH2_k127_4054261_3 Belongs to the peptidase S8 family K17734 - - 0.00000000000000000000000000000000000000000000000000000000001609 235.0
PYH2_k127_4054261_4 - K03561,K12287 - - 0.00000000000000000000000000000000000000000008435 184.0
PYH2_k127_4054261_5 OsmC-like protein - - - 0.0000000000000000000000000000000000000003521 156.0
PYH2_k127_4054261_6 DGC domain - - - 0.00000000000000000000000000000001544 136.0
PYH2_k127_4054261_7 - - - - 0.00000000000000000000000000001478 124.0
PYH2_k127_4054261_8 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000006379 122.0
PYH2_k127_4054261_9 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000003458 115.0
PYH2_k127_4062265_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.614e-195 631.0
PYH2_k127_4062265_1 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 409.0
PYH2_k127_4062265_10 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000005648 120.0
PYH2_k127_4062265_11 Tetratricopeptide repeat - - - 0.00000000000000000000000000002486 129.0
PYH2_k127_4062265_12 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000001128 107.0
PYH2_k127_4062265_14 Phosphorylase superfamily - - - 0.0000000000002747 80.0
PYH2_k127_4062265_16 CHAD domain containing protein - - - 0.0000000265 65.0
PYH2_k127_4062265_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K00945,K02945,K03527 - 1.17.7.4,2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 392.0
PYH2_k127_4062265_3 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 378.0
PYH2_k127_4062265_4 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 367.0
PYH2_k127_4062265_5 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006998 368.0
PYH2_k127_4062265_6 Ppx GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 363.0
PYH2_k127_4062265_7 PFAM Squalene phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009449 279.0
PYH2_k127_4062265_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000001595 213.0
PYH2_k127_4062265_9 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000004999 156.0
PYH2_k127_4074297_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000006036 209.0
PYH2_k127_4074297_1 Polysaccharide biosynthesis protein - - - 0.0000001939 61.0
PYH2_k127_4081092_0 Conserved repeat domain - - - 0.00000000000003024 86.0
PYH2_k127_4081092_1 O-Antigen ligase K18814 - - 0.000002838 60.0
PYH2_k127_4081676_0 pfkB family carbohydrate kinase K03272 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 301.0
PYH2_k127_4081676_1 nucleotide metabolic process - - - 0.000000000000000000000000000002488 130.0
PYH2_k127_4081676_2 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000146 103.0
PYH2_k127_4081676_3 - - - - 0.0000000001148 70.0
PYH2_k127_4125851_0 PFAM oxidoreductase domain protein - - - 0.00000000000001197 79.0
PYH2_k127_4127397_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 383.0
PYH2_k127_4127397_1 COG1205 Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster K06877 - - 0.0000000000000000000000000000008021 138.0
PYH2_k127_4128713_0 ABC transporter K01990,K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000002515 226.0
PYH2_k127_4128713_1 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000008064 162.0
PYH2_k127_4132602_0 spore germination K08978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 507.0
PYH2_k127_4132602_1 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 275.0
PYH2_k127_4132602_2 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000000003937 166.0
PYH2_k127_4132602_3 23S rRNA-intervening sequence protein - - - 0.00000000002354 65.0
PYH2_k127_4134557_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.043e-217 691.0
PYH2_k127_4134557_1 PFAM transposase IS4 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 462.0
PYH2_k127_4134557_2 Domain of unknown function (DUF5009) - - - 0.0000000000000000000000000000000000000000000000000005874 198.0
PYH2_k127_4134557_3 addiction module antidote protein HigA K21498 - - 0.00000000000000000000000000000000000000000002639 162.0
PYH2_k127_4134557_4 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000000000001366 145.0
PYH2_k127_4134557_5 Protein conserved in bacteria - - - 0.000003572 59.0
PYH2_k127_4134557_6 Psort location Cytoplasmic, score 9.26 K03592 - - 0.0005679 45.0
PYH2_k127_4148084_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 575.0
PYH2_k127_4148084_1 Glycosyltransferase like family 2 K00721,K10012 - 2.4.1.83,2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004383 286.0
PYH2_k127_4148084_2 ATP-grasp domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001883 262.0
PYH2_k127_4148084_3 methyltransferase - - - 0.00000000000000000000000000000004797 132.0
PYH2_k127_4148084_4 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000000000000004816 106.0
PYH2_k127_4148084_5 lysyltransferase activity K07027 - - 0.00000000000000003441 93.0
PYH2_k127_4177076_0 ADP-ribosylglycohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 479.0
PYH2_k127_4177076_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004491 353.0
PYH2_k127_4177076_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 347.0
PYH2_k127_4177076_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 336.0
PYH2_k127_4177076_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008225 341.0
PYH2_k127_4177076_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 330.0
PYH2_k127_4177076_6 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 298.0
PYH2_k127_4177076_7 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000004331 200.0
PYH2_k127_4185199_0 - - - - 0.00000000000000000000000000000000000000000000000008565 193.0
PYH2_k127_4185199_1 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000005773 70.0
PYH2_k127_4185199_2 Mycolic acid cyclopropane synthetase - - - 0.0007365 43.0
PYH2_k127_4204100_0 amino acid K03294 - - 1.145e-248 778.0
PYH2_k127_4204100_1 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009837 325.0
PYH2_k127_4204100_2 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 321.0
PYH2_k127_4204100_3 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 297.0
PYH2_k127_4204100_4 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 299.0
PYH2_k127_4204100_5 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000270,GO:0000271,GO:0003674,GO:0003824,GO:0003977,GO:0005975,GO:0005976,GO:0006022,GO:0006023,GO:0006024,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009252,GO:0009273,GO:0009987,GO:0016051,GO:0016740,GO:0016772,GO:0016779,GO:0030203,GO:0033692,GO:0034637,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0070569,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1903509 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000009873 160.0
PYH2_k127_4204100_6 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000283 113.0
PYH2_k127_4204100_7 Putative regulatory protein - - - 0.000001347 53.0
PYH2_k127_4204100_8 Tetratricopeptide repeat - - - 0.0001293 53.0
PYH2_k127_4208992_0 TIGRFAM Polyphosphate nucleotide phosphotransferase, PPK2 K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 396.0
PYH2_k127_4208992_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000003257 169.0
PYH2_k127_4226366_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006344 350.0
PYH2_k127_4226366_1 radical SAM domain protein K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000002287 165.0
PYH2_k127_4228910_0 carbohydrate binding - - - 0.0 3103.0
PYH2_k127_423553_0 Carboxypeptidase regulatory-like domain - - - 3.717e-233 754.0
PYH2_k127_423553_1 nuclease activity - - - 0.000000000000000000000000000000000000000000000002011 176.0
PYH2_k127_423553_3 Integrase - - - 0.00000000000006515 80.0
PYH2_k127_423553_5 Integrase - - - 0.0008562 43.0
PYH2_k127_424145_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 2.317e-262 824.0
PYH2_k127_424145_1 Carboxypeptidase regulatory-like domain - - - 5.638e-230 755.0
PYH2_k127_424145_2 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 306.0
PYH2_k127_4274302_0 - - - - 0.0000000000000000000000000000000000000001604 156.0
PYH2_k127_4294469_0 - - - - 8.451e-196 634.0
PYH2_k127_4294469_1 Aldose 1-epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000889 393.0
PYH2_k127_4294469_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 385.0
PYH2_k127_4294469_3 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
PYH2_k127_4305777_0 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007033 297.0
PYH2_k127_4305777_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007825 248.0
PYH2_k127_4305777_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000006438 180.0
PYH2_k127_4305777_3 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000000000000167 149.0
PYH2_k127_4305777_4 homoserine kinase activity K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000009574 124.0
PYH2_k127_4305777_5 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.000000000000000000000000000002112 125.0
PYH2_k127_4305777_6 Helix-hairpin-helix motif - - - 0.00000000000000000000447 97.0
PYH2_k127_4305777_7 PFAM Tetratricopeptide repeat - - - 0.00000000162 70.0
PYH2_k127_4314869_0 PFAM Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 505.0
PYH2_k127_4314869_1 Belongs to the bacterial plant glucose-1-phosphate adenylyltransferase family K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 467.0
PYH2_k127_4314869_10 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 258.0
PYH2_k127_4314869_11 deoxyribonuclease IV (phage-T4-induced) activity K01151 GO:0000726,GO:0003674,GO:0003824,GO:0003906,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0008833,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000001087 256.0
PYH2_k127_4314869_12 PFAM Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001821 250.0
PYH2_k127_4314869_13 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000001306 252.0
PYH2_k127_4314869_14 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000006179 243.0
PYH2_k127_4314869_15 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000001444 224.0
PYH2_k127_4314869_16 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000002173 224.0
PYH2_k127_4314869_17 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000000000001372 226.0
PYH2_k127_4314869_18 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000001471 215.0
PYH2_k127_4314869_19 PFAM GCN5-related N-acetyltransferase - - - 0.000000000000000000000000000000000000000000001095 173.0
PYH2_k127_4314869_2 Periplasmic component of the Tol biopolymer transport system K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 423.0
PYH2_k127_4314869_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006207 406.0
PYH2_k127_4314869_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K14161 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008849 383.0
PYH2_k127_4314869_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009001 334.0
PYH2_k127_4314869_6 Aminopeptidase P, N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 317.0
PYH2_k127_4314869_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K13832 - 1.1.1.25,4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 310.0
PYH2_k127_4314869_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000029 290.0
PYH2_k127_4314869_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000009501 271.0
PYH2_k127_4337390_0 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000002453 143.0
PYH2_k127_4337390_1 MreB/Mbl protein - - - 0.00000000000000000000001797 100.0
PYH2_k127_4337390_2 DnaJ molecular chaperone homology domain - - - 0.0000000001288 66.0
PYH2_k127_4337390_3 Phosphate acyltransferases K05939 - 2.3.1.40,6.2.1.20 0.0006466 48.0
PYH2_k127_4350153_0 ATP-dependent transcriptional regulator K03556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 495.0
PYH2_k127_4350153_1 NADPH quinone reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 467.0
PYH2_k127_4350153_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 299.0
PYH2_k127_4350153_3 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006091 287.0
PYH2_k127_4350153_4 - - - - 0.0000000000000000000000566 101.0
PYH2_k127_4378297_0 - - - - 0.00000000004106 76.0
PYH2_k127_4383379_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005986 527.0
PYH2_k127_4383379_1 zinc ion binding K02347,K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 517.0
PYH2_k127_4383379_2 glucosamine-6-phosphate deaminase activity K01057,K02564 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.1.1.31,3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007183 485.0
PYH2_k127_4383379_3 heme binding K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000001056 198.0
PYH2_k127_4383379_4 response regulator - - - 0.00000000000000000000000000000001262 135.0
PYH2_k127_4383379_5 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.0000000000000000000001656 98.0
PYH2_k127_4386719_0 ATP-grasp domain K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007685 393.0
PYH2_k127_4386719_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000005748 265.0
PYH2_k127_4386719_2 d-proline reductase K10794 - 1.21.4.1 0.0000000000000000000000000000000000001226 150.0
PYH2_k127_4386719_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000009524 138.0
PYH2_k127_4386719_4 - - - - 0.0000000000000000000001271 104.0
PYH2_k127_4386719_5 Predicted membrane protein (DUF2085) - - - 0.0000000000003489 76.0
PYH2_k127_43972_0 TonB-dependent receptor - - - 9.038e-254 823.0
PYH2_k127_43972_1 filamentation induced by cAMP protein Fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 574.0
PYH2_k127_43972_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006293 544.0
PYH2_k127_43972_3 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008228 481.0
PYH2_k127_43972_4 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 431.0
PYH2_k127_43972_5 addiction module antidote protein, CC2985 family - - - 0.00000000000000000000000000000000000000000003146 177.0
PYH2_k127_43972_6 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000000000000000000000000003002 168.0
PYH2_k127_43972_7 Domain of unknown function (DUF4258) - - - 0.00008782 48.0
PYH2_k127_43972_8 TIGRFAM YgiT-type zinc finger domain - - - 0.0009906 45.0
PYH2_k127_4410896_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term - - - 0.0 1084.0
PYH2_k127_4410896_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 2.823e-267 842.0
PYH2_k127_4410896_10 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 291.0
PYH2_k127_4410896_11 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000789 228.0
PYH2_k127_4410896_12 YceI-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008986 225.0
PYH2_k127_4410896_13 PHP-associated K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000814 235.0
PYH2_k127_4410896_14 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000001723 211.0
PYH2_k127_4410896_15 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000000000128 202.0
PYH2_k127_4410896_16 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000005476 183.0
PYH2_k127_4410896_17 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000004993 162.0
PYH2_k127_4410896_18 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000000000000000000008008 154.0
PYH2_k127_4410896_19 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000007635 153.0
PYH2_k127_4410896_2 efflux transmembrane transporter activity - - - 5.033e-248 791.0
PYH2_k127_4410896_20 PFAM ATP-binding region, ATPase domain protein - - - 0.00000000000000000000000000000000000000166 165.0
PYH2_k127_4410896_21 DRTGG domain - - - 0.0000000000000000000000000001136 119.0
PYH2_k127_4410896_22 DRTGG domain - - - 0.0000000000000000000000000007137 117.0
PYH2_k127_4410896_23 mannose metabolic process K01191 - 3.2.1.24 0.0000000000000000000002082 98.0
PYH2_k127_4410896_24 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000001193 96.0
PYH2_k127_4410896_25 COG1846 Transcriptional regulators - - - 0.000004854 56.0
PYH2_k127_4410896_3 Sodium:solute symporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 512.0
PYH2_k127_4410896_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007276 453.0
PYH2_k127_4410896_5 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 440.0
PYH2_k127_4410896_6 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 427.0
PYH2_k127_4410896_7 Histidine kinase HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002749 434.0
PYH2_k127_4410896_8 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008604 353.0
PYH2_k127_4410896_9 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009477 343.0
PYH2_k127_447431_0 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000003444 243.0
PYH2_k127_447431_1 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000007266 136.0
PYH2_k127_447431_2 - - - - 0.000000000000000000000000000000007297 130.0
PYH2_k127_447431_3 GDSL-like Lipase/Acylhydrolase - - - 0.0000000008633 68.0
PYH2_k127_452371_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.09e-310 987.0
PYH2_k127_452371_1 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.388e-253 795.0
PYH2_k127_452371_2 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 458.0
PYH2_k127_452371_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 366.0
PYH2_k127_452371_4 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 291.0
PYH2_k127_452371_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 297.0
PYH2_k127_452371_6 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.0000000000000000000000000000000000000000000000000000000000000000007249 237.0
PYH2_k127_452371_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272,K21345 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000003169 194.0
PYH2_k127_452371_8 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000004418 115.0
PYH2_k127_4534701_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000001089 161.0
PYH2_k127_4534701_1 PFAM glycosyl transferase family 39 - - - 0.0000000000000004637 89.0
PYH2_k127_4546086_0 Phosphoesterase family - - - 8.275e-242 773.0
PYH2_k127_4546086_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 550.0
PYH2_k127_4546086_2 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 372.0
PYH2_k127_4546086_3 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 329.0
PYH2_k127_4546086_4 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000006103 175.0
PYH2_k127_4546086_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000001035 114.0
PYH2_k127_4546086_6 Dodecin K09165 - - 0.000000000000000000001757 96.0
PYH2_k127_4546086_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000004436 65.0
PYH2_k127_4553757_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000002941 232.0
PYH2_k127_4553757_1 Inositol monophosphatase family - - - 0.000000000000000000000000000000000000000001759 162.0
PYH2_k127_4553757_3 myo-inosose-2 dehydratase activity - - - 0.00000002452 60.0
PYH2_k127_4553879_0 Aminotransferase K21572 - - 0.0 1897.0
PYH2_k127_4553879_1 Selenate reductase K12527 - 1.97.1.9 0.0 1389.0
PYH2_k127_4553879_10 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009932 483.0
PYH2_k127_4553879_11 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 473.0
PYH2_k127_4553879_12 beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 413.0
PYH2_k127_4553879_13 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 359.0
PYH2_k127_4553879_14 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 333.0
PYH2_k127_4553879_15 protein kinase related protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 330.0
PYH2_k127_4553879_16 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 321.0
PYH2_k127_4553879_17 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 306.0
PYH2_k127_4553879_18 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007048 287.0
PYH2_k127_4553879_19 FMN-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007843 263.0
PYH2_k127_4553879_2 Pyridoxal-phosphate dependent enzyme - - - 4.713e-234 734.0
PYH2_k127_4553879_20 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K02003,K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000002668 243.0
PYH2_k127_4553879_21 COG2226 Methylase involved in ubiquinone menaquinone biosynthesis K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000007259 226.0
PYH2_k127_4553879_22 - K03616 - - 0.000000000000000000000000000000002875 138.0
PYH2_k127_4553879_23 amine dehydrogenase activity - - - 0.000000000000000000000000003084 125.0
PYH2_k127_4553879_24 - - - - 0.0000068 53.0
PYH2_k127_4553879_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335,K18331 - 1.12.1.3,1.6.5.3 1.359e-216 705.0
PYH2_k127_4553879_4 PFAM amidohydrolase K01464 - 3.5.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 604.0
PYH2_k127_4553879_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004384 604.0
PYH2_k127_4553879_6 Belongs to the ATCase OTCase family - GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0019627,GO:0034641,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 553.0
PYH2_k127_4553879_7 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 552.0
PYH2_k127_4553879_8 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 534.0
PYH2_k127_4553879_9 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 518.0
PYH2_k127_4586627_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 379.0
PYH2_k127_4586627_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003814 263.0
PYH2_k127_4586627_2 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000111 242.0
PYH2_k127_4586627_3 nucleotidyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000001677 228.0
PYH2_k127_4586627_4 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000205 171.0
PYH2_k127_461155_0 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 387.0
PYH2_k127_461155_1 - - - - 0.000000000000000000000000000000001969 136.0
PYH2_k127_461155_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000000000000009422 130.0
PYH2_k127_461155_3 - - - - 0.0007114 47.0
PYH2_k127_4622479_0 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 351.0
PYH2_k127_4622479_1 Type II secretion system (T2SS), protein K K02460 - - 0.0000000000000000000000000000000000000000000000000007543 196.0
PYH2_k127_4622479_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000001384 160.0
PYH2_k127_4622479_3 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 0.000000000000000000004804 94.0
PYH2_k127_4622479_4 pilus assembly protein PilW K02459 - - 0.0000000000001107 81.0
PYH2_k127_4622479_5 Fimbrial assembly protein (PilN) - - - 0.000000000002597 79.0
PYH2_k127_4622479_6 Type II secretion system (T2SS), protein M subtype b K02462 - - 0.0000000004252 68.0
PYH2_k127_4622479_7 General secretion pathway protein H K02457 - - 0.00000001396 65.0
PYH2_k127_4622479_8 Prokaryotic N-terminal methylation motif K02458 - - 0.00000878 56.0
PYH2_k127_46299_0 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000001075 94.0
PYH2_k127_46299_1 cell redox homeostasis K02199 - - 0.000000000000001193 88.0
PYH2_k127_4670497_0 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 572.0
PYH2_k127_4670497_1 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 325.0
PYH2_k127_4670497_2 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000004609 217.0
PYH2_k127_4670497_3 - - - - 0.000000000000000000000000000000000000000000000005241 179.0
PYH2_k127_4670497_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000299 53.0
PYH2_k127_4693039_0 Putative peptidoglycan binding domain - - - 0.0000000000000000000000000000000000000000003139 165.0
PYH2_k127_4703582_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 561.0
PYH2_k127_4703582_1 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 535.0
PYH2_k127_4703582_10 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 369.0
PYH2_k127_4703582_11 alanine dehydrogenase activity K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 356.0
PYH2_k127_4703582_12 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004344 256.0
PYH2_k127_4703582_13 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000001462 178.0
PYH2_k127_4703582_14 Pas domain - - - 0.00000000000000000000000000000000000000002455 175.0
PYH2_k127_4703582_15 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000001107 157.0
PYH2_k127_4703582_16 DNA photolyase activity K03716 - 4.1.99.14 0.000000000000007397 77.0
PYH2_k127_4703582_17 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000002948 64.0
PYH2_k127_4703582_2 oxidoreductase K13020 - 1.1.1.335 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 510.0
PYH2_k127_4703582_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007974 486.0
PYH2_k127_4703582_4 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 460.0
PYH2_k127_4703582_5 PFAM Alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 443.0
PYH2_k127_4703582_6 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 434.0
PYH2_k127_4703582_7 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002753 415.0
PYH2_k127_4703582_8 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 412.0
PYH2_k127_4703582_9 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 372.0
PYH2_k127_4705303_0 AAA ATPase domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000002266 209.0
PYH2_k127_4705303_1 SpoU rRNA Methylase family - - - 0.000000000000000000000000000000000000000005086 162.0
PYH2_k127_4705303_2 Dehydrogenase - - - 0.00000000006293 64.0
PYH2_k127_4705426_0 Aldo/keto reductase family - - - 0.0000000000000000000002374 109.0
PYH2_k127_4705426_1 Acetyl xylan esterase (AXE1) - - - 0.0000001996 53.0
PYH2_k127_4705426_2 TIGRFAM cytochrome C family protein - - - 0.00001253 55.0
PYH2_k127_4707278_0 PFAM transposase IS204 IS1001 IS1096 IS1165 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 597.0
PYH2_k127_4707278_1 TAT (twin-arginine translocation) pathway signal sequence - - - 0.00000000000000000000000000000000000000000000000006193 182.0
PYH2_k127_4707278_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000003657 114.0
PYH2_k127_4709745_0 lactate metabolic process - - - 2.185e-215 687.0
PYH2_k127_4709745_1 NAD binding K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 488.0
PYH2_k127_4709745_10 Methionine aminopeptidase K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 315.0
PYH2_k127_4709745_11 PBP superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004211 319.0
PYH2_k127_4709745_12 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002389 280.0
PYH2_k127_4709745_13 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004094 273.0
PYH2_k127_4709745_14 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000006073 273.0
PYH2_k127_4709745_15 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000226 268.0
PYH2_k127_4709745_16 Binding-protein-dependent transport system inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006098 263.0
PYH2_k127_4709745_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001808 254.0
PYH2_k127_4709745_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000209 243.0
PYH2_k127_4709745_19 Putative zinc-binding metallo-peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001663 243.0
PYH2_k127_4709745_2 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 479.0
PYH2_k127_4709745_20 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000004416 223.0
PYH2_k127_4709745_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03615,K05580 - 1.6.5.3 0.0000000000000000000000000000000000000000000243 166.0
PYH2_k127_4709745_22 PFAM NADH-ubiquinone plastoquinone oxidoreductase, chain 6 K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000271 157.0
PYH2_k127_4709745_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000001475 154.0
PYH2_k127_4709745_24 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000009976 160.0
PYH2_k127_4709745_25 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000237 150.0
PYH2_k127_4709745_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000003459 151.0
PYH2_k127_4709745_27 Redoxin - - - 0.0000000000000000000000000000001117 131.0
PYH2_k127_4709745_28 ATP synthesis coupled electron transport K00340,K05576 - 1.6.5.3 0.0000000000000000000000000000007981 124.0
PYH2_k127_4709745_29 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000006544 126.0
PYH2_k127_4709745_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 463.0
PYH2_k127_4709745_30 regulatory protein K11923,K13638 - - 0.0000000000000000001478 94.0
PYH2_k127_4709745_31 Uncharacterized conserved protein (DUF2203) - - - 0.0001978 49.0
PYH2_k127_4709745_4 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 458.0
PYH2_k127_4709745_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337,K05572 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0044237,GO:0045333,GO:0050136,GO:0055114 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 403.0
PYH2_k127_4709745_6 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 404.0
PYH2_k127_4709745_7 Dehydrogenase E1 component K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 394.0
PYH2_k127_4709745_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001919 391.0
PYH2_k127_4709745_9 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 360.0
PYH2_k127_4710952_0 PFAM Sulfatase K01130 - 3.1.6.1 0.0 1322.0
PYH2_k127_4710952_1 PFAM Sulfatase K01130 - 3.1.6.1 0.0 1302.0
PYH2_k127_4710952_10 Ecotin K08276 - - 0.0000000000000000000000000001973 117.0
PYH2_k127_4710952_11 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000001238 84.0
PYH2_k127_4710952_12 Belongs to the SfsA family K06206 - - 0.000000000006706 66.0
PYH2_k127_4710952_13 Protein of unknown function (DUF1214) - - - 0.000000001038 60.0
PYH2_k127_4710952_14 - - - - 0.000009081 50.0
PYH2_k127_4710952_2 Sulfatase K01135 - 3.1.6.12 4.709e-232 726.0
PYH2_k127_4710952_3 Sulfatase K01135 - 3.1.6.12 1.892e-231 725.0
PYH2_k127_4710952_4 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 1.201e-200 642.0
PYH2_k127_4710952_5 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005717 513.0
PYH2_k127_4710952_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 325.0
PYH2_k127_4710952_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004135 256.0
PYH2_k127_4710952_8 Na -dependent transporter K03453 - - 0.00000000000000000000000000000000000000000000000000000001481 207.0
PYH2_k127_4710952_9 Haemolytic - - - 0.00000000000000000000000000002226 122.0
PYH2_k127_4713569_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000006146 78.0
PYH2_k127_4713569_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000004967 81.0
PYH2_k127_4713569_2 BlaR1 peptidase M56 - - - 0.0000000000001128 81.0
PYH2_k127_4713569_3 BlaR1 peptidase M56 - - - 0.0000000000007177 75.0
PYH2_k127_4721251_0 HicA toxin of bacterial toxin-antitoxin, K07339 - - 0.0000000000000000000000001653 106.0
PYH2_k127_4721251_1 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000008939 105.0
PYH2_k127_4721251_2 Transposase - - - 0.0000000000000000000001753 99.0
PYH2_k127_4721279_0 Capsule polysaccharide biosynthesis protein K07265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 420.0
PYH2_k127_4721279_1 transposition K07497 - - 0.000001858 54.0
PYH2_k127_4724422_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009457 264.0
PYH2_k127_4724422_1 AAA domain K06919 - - 0.0000000000000000000000000000000000000000000000000003415 198.0
PYH2_k127_4724422_2 DNA primase - - - 0.0000000000000001027 87.0
PYH2_k127_4736580_0 response regulator K10943 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 424.0
PYH2_k127_4736580_1 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000369 264.0
PYH2_k127_4736580_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001721 196.0
PYH2_k127_4736580_3 Uncharacterized protein domain (DUF2202) - - - 0.00000000000000000000000000000000000000000000000006276 192.0
PYH2_k127_4736580_4 PIN domain K07065 - - 0.00000000000000000000002957 106.0
PYH2_k127_4736580_6 Plasmid stability protein K21495 - - 0.0000000004351 64.0
PYH2_k127_4736580_7 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000007844 62.0
PYH2_k127_4736580_8 Domain of unknown function (DUF4405) - - - 0.00000001619 61.0
PYH2_k127_4746479_0 Sodium:solute symporter family - - - 3.741e-305 944.0
PYH2_k127_4746479_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 505.0
PYH2_k127_4746479_10 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001521 253.0
PYH2_k127_4746479_2 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 477.0
PYH2_k127_4746479_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 438.0
PYH2_k127_4746479_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 414.0
PYH2_k127_4746479_5 KduI/IolB family K01815 - 5.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 325.0
PYH2_k127_4746479_6 Catalyzes the formation of 3-dehydro-2-deoxy-D-gluconate from 2-deoxy-D-gluconate K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 328.0
PYH2_k127_4746479_7 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 353.0
PYH2_k127_4746479_8 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 327.0
PYH2_k127_4746479_9 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 311.0
PYH2_k127_4749667_0 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000004942 118.0
PYH2_k127_4749851_0 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 451.0
PYH2_k127_4749851_1 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 441.0
PYH2_k127_4749851_2 DinB family - - - 0.000000000000000000000000000004927 125.0
PYH2_k127_4749851_3 pilus assembly protein PilW K02672 - - 0.0000000000000000000179 103.0
PYH2_k127_4749851_4 COG1943 Transposase and inactivated derivatives - - - 0.00000000000000001839 83.0
PYH2_k127_4749851_5 Domain of unknown function (DUF4258) - - - 0.000000000003039 75.0
PYH2_k127_4749851_6 PFAM transcriptional regulator PadR family protein - - - 0.00000001178 61.0
PYH2_k127_4749851_7 Methyltransferase domain K09915 - - 0.0000105 52.0
PYH2_k127_4749851_8 - - - - 0.00004851 46.0
PYH2_k127_4753959_0 PFAM Integrase catalytic - - - 4.432e-209 662.0
PYH2_k127_4753959_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009432 329.0
PYH2_k127_4758332_0 beta-galactosidase activity - - - 0.0 1103.0
PYH2_k127_4758332_1 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1015.0
PYH2_k127_4758332_10 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001988 376.0
PYH2_k127_4758332_11 PFAM molybdopterin dehydrogenase, FAD-binding K11178 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 368.0
PYH2_k127_4758332_12 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 357.0
PYH2_k127_4758332_13 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 343.0
PYH2_k127_4758332_14 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 332.0
PYH2_k127_4758332_15 TonB dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 331.0
PYH2_k127_4758332_16 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007484 296.0
PYH2_k127_4758332_17 Oligopeptide/dipeptide transporter, C-terminal region K02032,K10823,K12372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000167 253.0
PYH2_k127_4758332_18 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000002047 235.0
PYH2_k127_4758332_19 2Fe-2S -binding K13483 - - 0.0000000000000000000000000000000000000000000000000000002219 201.0
PYH2_k127_4758332_2 CHAT domain - - - 7.077e-295 937.0
PYH2_k127_4758332_20 Iron-storage protein K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000007296 195.0
PYH2_k127_4758332_21 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.00000000000000000000000000000000000000000000000008469 196.0
PYH2_k127_4758332_22 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000002665 151.0
PYH2_k127_4758332_24 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000003686 115.0
PYH2_k127_4758332_25 PFAM Response regulator receiver domain - - - 0.00000000000000000000004477 107.0
PYH2_k127_4758332_26 Peptidase family M28 - - - 0.0000000000000006372 78.0
PYH2_k127_4758332_28 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source K10778 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 2.1.1.63 0.0000003194 55.0
PYH2_k127_4758332_29 Selenoprotein, putative - - - 0.0000009819 52.0
PYH2_k127_4758332_3 5TM C-terminal transporter carbon starvation CstA K06200 - - 1.563e-283 886.0
PYH2_k127_4758332_30 - - - - 0.000132 48.0
PYH2_k127_4758332_4 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K11177 - 1.17.1.4 6.965e-264 830.0
PYH2_k127_4758332_5 metallocarboxypeptidase activity K14054 - - 6.64e-244 781.0
PYH2_k127_4758332_6 extracellular solute-binding protein, family 5 K02035 - - 7.743e-195 624.0
PYH2_k127_4758332_7 Isocitrate/isopropylmalate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 599.0
PYH2_k127_4758332_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 465.0
PYH2_k127_4758332_9 polygalacturonase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 426.0
PYH2_k127_4760349_0 PFAM Integrase catalytic - - - 1.222e-208 660.0
PYH2_k127_4760349_1 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 335.0
PYH2_k127_4770778_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000003691 213.0
PYH2_k127_4770778_1 ADP binding - - - 0.0000000000000000000000000000009147 124.0
PYH2_k127_4770778_2 Belongs to the 'phage' integrase family - - - 0.000000000000001592 79.0
PYH2_k127_4772473_0 Sodium:sulfate symporter transmembrane region K14445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 426.0
PYH2_k127_4772473_1 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000000000000000000000000003836 204.0
PYH2_k127_4772473_2 pathogenesis K01077,K01119,K11751,K20276 - 3.1.3.1,3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.00000000000000000001006 109.0
PYH2_k127_4772473_3 Glutathione peroxidase K02199 - - 0.000000000000000001972 93.0
PYH2_k127_4772473_4 response to stress - - - 0.0000000000000001693 90.0
PYH2_k127_4772473_5 23S rRNA-intervening sequence protein - - - 0.000000008464 58.0
PYH2_k127_4772473_6 Bacterial pre-peptidase C-terminal domain - - - 0.0000001386 66.0
PYH2_k127_4772473_7 GDSL-like Lipase/Acylhydrolase - - - 0.0000005478 64.0
PYH2_k127_4772473_8 Periplasmic copper-binding protein (NosD) - - - 0.00000125 63.0
PYH2_k127_4788444_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 584.0
PYH2_k127_4788444_1 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 392.0
PYH2_k127_4788444_2 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000002558 83.0
PYH2_k127_4788444_3 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001965 68.0
PYH2_k127_4790936_0 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 605.0
PYH2_k127_4790936_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 551.0
PYH2_k127_4790936_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946,K07123 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009030,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009229,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042357,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000195 219.0
PYH2_k127_4790936_11 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000005645 205.0
PYH2_k127_4790936_12 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000007144 208.0
PYH2_k127_4790936_13 Isochorismate synthase K02552 - 5.4.4.2 0.000000000000000000000000000000000000000000000000000000003757 211.0
PYH2_k127_4790936_14 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000002507 188.0
PYH2_k127_4790936_15 AIR carboxylase K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000556 180.0
PYH2_k127_4790936_16 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000003002 181.0
PYH2_k127_4790936_17 mRNA cleavage K19158 - - 0.0000000000000000000000000000000000004496 141.0
PYH2_k127_4790936_18 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000003132 121.0
PYH2_k127_4790936_19 Putative adhesin - - - 0.0000000000000000000000000003474 132.0
PYH2_k127_4790936_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 509.0
PYH2_k127_4790936_20 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000005486 115.0
PYH2_k127_4790936_21 multi-organism process - - - 0.0000000000000000000000000007078 123.0
PYH2_k127_4790936_22 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000012 107.0
PYH2_k127_4790936_23 - - - - 0.0000000000000000001983 96.0
PYH2_k127_4790936_24 - - - - 0.00000000004981 67.0
PYH2_k127_4790936_25 DnaJ-class molecular chaperone with C-terminal Zn finger domain - - - 0.000001986 60.0
PYH2_k127_4790936_26 CAAX protease self-immunity K07052 - - 0.000003979 59.0
PYH2_k127_4790936_28 AntiSigma factor - - - 0.0002561 51.0
PYH2_k127_4790936_3 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 417.0
PYH2_k127_4790936_4 Belongs to the peptidase M16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001605 414.0
PYH2_k127_4790936_5 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 403.0
PYH2_k127_4790936_6 SMART Elongator protein 3 MiaB NifB K18707 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0034470,GO:0034641,GO:0034660,GO:0035596,GO:0035598,GO:0035600,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0050497,GO:0071704,GO:0090304,GO:1901360 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 353.0
PYH2_k127_4790936_7 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000049,GO:0000154,GO:0001510,GO:0002935,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016426,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070040,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:0140102,GO:1901360,GO:1901363 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 323.0
PYH2_k127_4790936_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005088 249.0
PYH2_k127_4790936_9 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001636 235.0
PYH2_k127_4814596_0 L-lactate permease K03303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 485.0
PYH2_k127_4821760_0 Cys/Met metabolism PLP-dependent enzyme K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 556.0
PYH2_k127_4821760_1 Domain of unknown function (DUF1731) K07071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 331.0
PYH2_k127_4821760_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000792 327.0
PYH2_k127_4821760_3 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004179 317.0
PYH2_k127_4821760_4 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000181 301.0
PYH2_k127_4821760_5 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002093 272.0
PYH2_k127_4821760_6 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000000000000005287 151.0
PYH2_k127_4822399_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 4.215e-218 686.0
PYH2_k127_4822399_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 552.0
PYH2_k127_4822399_10 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 326.0
PYH2_k127_4822399_11 Belongs to the SEDS family K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005776 305.0
PYH2_k127_4822399_12 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 298.0
PYH2_k127_4822399_13 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 311.0
PYH2_k127_4822399_14 3' exoribonuclease family, domain 2 K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 291.0
PYH2_k127_4822399_15 Enoyl-(Acyl carrier protein) reductase K00038 - 1.1.1.53 0.00000000000000000000000000000000000000000000000000000000000000000008325 239.0
PYH2_k127_4822399_16 Methionine synthase B12-binding module cap domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003471 228.0
PYH2_k127_4822399_17 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000004659 195.0
PYH2_k127_4822399_18 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000001791 183.0
PYH2_k127_4822399_19 Belongs to the MraZ family K03925 - - 0.00000000000000000000000000000001903 131.0
PYH2_k127_4822399_2 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 475.0
PYH2_k127_4822399_20 Cell division protein FtsQ K03589 - - 0.000000000000000004505 95.0
PYH2_k127_4822399_21 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000007545 59.0
PYH2_k127_4822399_22 Cell division protein FtsL - - - 0.0000005486 57.0
PYH2_k127_4822399_23 - - - - 0.0001416 44.0
PYH2_k127_4822399_3 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 444.0
PYH2_k127_4822399_4 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002346 420.0
PYH2_k127_4822399_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 399.0
PYH2_k127_4822399_6 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 379.0
PYH2_k127_4822399_7 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009276 401.0
PYH2_k127_4822399_8 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 353.0
PYH2_k127_4822399_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 345.0
PYH2_k127_4845326_0 protein transport across the cell outer membrane K02453,K03219 - - 0.0000000000000000000000000000000000000000000000000000000000003358 239.0
PYH2_k127_4845326_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000002959 70.0
PYH2_k127_4853637_0 PFAM GGDEF domain containing protein K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 327.0
PYH2_k127_4853637_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000001686 250.0
PYH2_k127_4853637_2 Glycosyl hydrolase family 65, N-terminal domain - - - 0.0000000000000000000000000000000000000008351 155.0
PYH2_k127_4853637_3 Integrase core domain - - - 0.0000000000000000000000000000003397 129.0
PYH2_k127_4853637_4 Phage integrase family - - - 0.0000000000000000000000009509 109.0
PYH2_k127_4853637_5 - - - - 0.00000000000000000008882 92.0
PYH2_k127_4857801_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000923 243.0
PYH2_k127_4861958_0 Transposase DDE domain - - - 4.796e-250 783.0
PYH2_k127_4862207_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000005609 171.0
PYH2_k127_4862207_1 B12 binding domain - - - 0.0000000000000000000000000015 115.0
PYH2_k127_4862207_2 B12 binding domain - - - 0.0000000000000000000000306 104.0
PYH2_k127_4862207_3 response to heat - - - 0.00000000000001036 78.0
PYH2_k127_4866807_0 PFAM carbohydrate kinase K00853 - 2.7.1.16 3.423e-240 750.0
PYH2_k127_4866807_1 L-fucose isomerase, C-terminal domain - - - 1.408e-229 720.0
PYH2_k127_4866807_2 PFAM General secretory system II protein E domain protein K11740 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 503.0
PYH2_k127_4866807_3 inositol monophosphate 1-phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 412.0
PYH2_k127_4866807_4 MacB-like periplasmic core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 350.0
PYH2_k127_4866807_5 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 330.0
PYH2_k127_4866807_6 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 297.0
PYH2_k127_4866807_7 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001492 269.0
PYH2_k127_4866816_0 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00128,K00138 - 1.2.1.3 1.88e-286 884.0
PYH2_k127_4866816_1 Pfam:DUF303 K05970 - 3.1.1.53 4.145e-250 782.0
PYH2_k127_4866816_10 Protein of unknown function (DUF779) K09959 - - 0.000000000000000000000000000000000000000000000000000000000001846 212.0
PYH2_k127_4866816_11 - - - - 0.00000000000000000000000000000000000000000005889 171.0
PYH2_k127_4866816_12 TPM domain K06872 - - 0.00000000000001223 76.0
PYH2_k127_4866816_13 Catalyzes the conversion of GlcNAc-PP-undecaprenol into ManNAc-GlcNAc-PP-undecaprenol, the first committed lipid intermediate in the de novo synthesis of teichoic acid K05946 - 2.4.1.187 0.0000001116 53.0
PYH2_k127_4866816_2 Beta-L-arabinofuranosidase, GH127 - - - 1.725e-246 778.0
PYH2_k127_4866816_3 Oxidoreductase - - - 6.646e-200 632.0
PYH2_k127_4866816_4 pyrroloquinoline quinone binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 634.0
PYH2_k127_4866816_5 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000367 438.0
PYH2_k127_4866816_6 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 433.0
PYH2_k127_4866816_7 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001801 282.0
PYH2_k127_4866816_8 Trehalose utilisation - - - 0.00000000000000000000000000000000000000000000000000000000000000001304 237.0
PYH2_k127_4866816_9 ABC-2 type transporter K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000004522 225.0
PYH2_k127_4869231_0 ferrous iron transmembrane transporter activity K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 498.0
PYH2_k127_4869231_1 1-aminocyclopropane-1-carboxylate deaminase K05396 - 4.4.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 329.0
PYH2_k127_4869231_2 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 307.0
PYH2_k127_4869231_3 iron ion homeostasis K03709,K04758 - - 0.0000000000000000000000000000000000000000000003065 177.0
PYH2_k127_4869231_4 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000758 87.0
PYH2_k127_4869231_5 protein transport across the cell outer membrane K02246,K08084 - - 0.0000004888 58.0
PYH2_k127_4869826_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 4.297e-294 934.0
PYH2_k127_4869826_1 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006125 527.0
PYH2_k127_4869826_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 388.0
PYH2_k127_4869826_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000128 284.0
PYH2_k127_4869826_4 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000003284 264.0
PYH2_k127_4869826_5 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000005718 192.0
PYH2_k127_4869826_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000003779 123.0
PYH2_k127_4870862_0 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 409.0
PYH2_k127_4870862_1 Oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 364.0
PYH2_k127_4870862_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005284 321.0
PYH2_k127_4870862_3 COGs COG5499 transcription regulator containing HTH domain K18831 - - 0.000000000000000000000000000006443 123.0
PYH2_k127_4870862_4 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000009371 117.0
PYH2_k127_4870862_5 HigB_toxin, RelE-like toxic component of a toxin-antitoxin system K19166 - - 0.00000000000000000000000006413 110.0
PYH2_k127_4879888_0 pfkB family carbohydrate kinase - - - 3.287e-203 636.0
PYH2_k127_4879888_1 CO dehydrogenase flavoprotein C-terminal domain K11178 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000005291 260.0
PYH2_k127_4879888_2 - - - - 0.000000000003146 74.0
PYH2_k127_4886222_0 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 486.0
PYH2_k127_4886222_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000002527 262.0
PYH2_k127_4886222_2 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000009787 233.0
PYH2_k127_4886222_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000002365 64.0
PYH2_k127_489078_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K19956 - - 1.437e-214 672.0
PYH2_k127_489078_1 Tricorn protease homolog K08676 - - 0.0000000000000000000000000000000000000000000000000000000000000000002957 234.0
PYH2_k127_4892312_0 beta-galactosidase activity - - - 0.0 1143.0
PYH2_k127_4892312_1 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 469.0
PYH2_k127_4892312_10 pfkB family carbohydrate kinase - - - 0.000000000000000002259 86.0
PYH2_k127_4892312_11 toxin-antitoxin pair type II binding - - - 0.0000000001762 68.0
PYH2_k127_4892312_12 PFAM TonB-dependent Receptor Plug - - - 0.0000000005274 63.0
PYH2_k127_4892312_13 TonB-dependent Receptor Plug Domain - - - 0.000001619 54.0
PYH2_k127_4892312_14 Domain of unknown function (DUF4276) - - - 0.000009161 49.0
PYH2_k127_4892312_15 Helix-turn-helix domain - - - 0.0001846 49.0
PYH2_k127_4892312_2 Tagatose 6 phosphate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 429.0
PYH2_k127_4892312_3 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 416.0
PYH2_k127_4892312_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 347.0
PYH2_k127_4892312_5 COG1105 Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) K00917 - 2.7.1.144 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000282 289.0
PYH2_k127_4892312_6 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.00000000000000000000000000000000000000000000002514 171.0
PYH2_k127_4892312_7 Elongation factor P K02356 - - 0.000000000000000000000000000000000000000000002984 170.0
PYH2_k127_4892312_8 Nucleotidyltransferase domain K07076 - - 0.000000000000000000000000000000001255 132.0
PYH2_k127_4892312_9 PIN domain - - - 0.000000000000000001102 93.0
PYH2_k127_4909438_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 1.575e-205 646.0
PYH2_k127_4909438_1 Methionine sulfoxide reductase - - - 0.0000000000000000000006636 96.0
PYH2_k127_490991_0 mannose metabolic process K01191 - 3.2.1.24 0.0 1037.0
PYH2_k127_4909950_0 Oligoendopeptidase f - - - 2.096e-251 795.0
PYH2_k127_4909950_1 Protein involved in outer membrane biogenesis K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 445.0
PYH2_k127_4909950_2 N-acylglucosamine 2-epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000008754 244.0
PYH2_k127_4909950_3 Thioredoxin - - - 0.000000000000000003969 90.0
PYH2_k127_4909950_4 Putative adhesin - - - 0.0000000003033 70.0
PYH2_k127_4910170_0 OPT oligopeptide transporter protein - - - 3.975e-229 718.0
PYH2_k127_4931619_0 Transposase DDE domain group 1 - - - 0.00000000000000000000000000000000000000000000000001516 198.0
PYH2_k127_4931619_1 Serine hydrolase involved in the detoxification of formaldehyde K01070 - 3.1.2.12 0.0000000005207 62.0
PYH2_k127_4937752_0 FAD dependent oxidoreductase - - - 5.613e-242 759.0
PYH2_k127_4937752_1 O-linked N-acetylglucosamine transferase SPINDLY family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 462.0
PYH2_k127_4937752_2 acetylesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 424.0
PYH2_k127_4937752_3 Glycosyl transferase family group 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005152 412.0
PYH2_k127_4937752_4 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 - 3.2.1.78 0.000000000000000000000000000000000000000000000000000000000000000000000000000001152 296.0
PYH2_k127_4937752_5 Glycosyl hydrolase family 26 K01218 - 3.2.1.78 0.0000000000000000000000000000000000000000000000001346 203.0
PYH2_k127_4937752_6 PFAM plasmid K06218 - - 0.0000000000000000000000000005233 115.0
PYH2_k127_4937752_7 Protein of unknown function (DUF2442) - - - 0.000000000000000000000000008336 111.0
PYH2_k127_4937752_8 - - - - 0.00000000000000000002626 92.0
PYH2_k127_493867_0 L-fucose isomerase and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 454.0
PYH2_k127_493867_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 320.0
PYH2_k127_493867_2 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 302.0
PYH2_k127_493867_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000005919 223.0
PYH2_k127_493867_4 - - - - 0.0000000000000000000000000000000000000000000000002661 183.0
PYH2_k127_4948853_0 Amino acid permease - - - 7.039e-320 995.0
PYH2_k127_4948853_1 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 433.0
PYH2_k127_4983573_0 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000001583 68.0
PYH2_k127_5004389_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 470.0
PYH2_k127_5004389_1 ABC transporter K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008193 400.0
PYH2_k127_5004389_2 Neutral/alkaline non-lysosomal ceramidase, N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 377.0
PYH2_k127_5004389_3 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 328.0
PYH2_k127_5004389_4 Binding-protein-dependent transport system inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 309.0
PYH2_k127_500492_0 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000159 417.0
PYH2_k127_500492_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 407.0
PYH2_k127_500492_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 373.0
PYH2_k127_500492_3 Domain of unknown function (DUF4389) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 285.0
PYH2_k127_500492_4 Nodulation protein S (NodS) - - - 0.000000000000000000000000000000000000000000000000000227 192.0
PYH2_k127_500492_5 Domain of unknown function (DUF4386) - - - 0.00000000000000000000000000000000001151 145.0
PYH2_k127_5014075_0 PFAM Transposase DDE domain - - - 1.808e-197 625.0
PYH2_k127_5020134_0 Domain of unknown function (DUF5060) - - - 1.913e-216 688.0
PYH2_k127_5020134_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003979 462.0
PYH2_k127_5020134_10 Alpha/beta hydrolase family - - - 0.000000000000000000000000000001518 134.0
PYH2_k127_5020134_11 Response regulator receiver - - - 0.000000000000000000000000007439 123.0
PYH2_k127_5020134_12 3'(2'),5'-bisphosphate nucleotidase activity - - - 0.000000002192 58.0
PYH2_k127_5020134_13 YtxH-like protein - - - 0.00000002557 59.0
PYH2_k127_5020134_14 - - - - 0.00041 49.0
PYH2_k127_5020134_2 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003198 459.0
PYH2_k127_5020134_3 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 421.0
PYH2_k127_5020134_4 Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 414.0
PYH2_k127_5020134_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 406.0
PYH2_k127_5020134_6 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000069 256.0
PYH2_k127_5020134_7 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001123 258.0
PYH2_k127_5020134_8 permease - - - 0.0000000000000000000000000000000000000000000005953 180.0
PYH2_k127_5020134_9 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000006911 168.0
PYH2_k127_5021449_0 amidohydrolase - - - 0.00000000000000000008104 104.0
PYH2_k127_5021449_1 PFAM ATP-binding region ATPase domain protein, histidine kinase A domain protein - - - 0.00000000003495 65.0
PYH2_k127_5068648_0 SMART Elongator protein 3 MiaB NifB - - - 5.58e-200 634.0
PYH2_k127_5068648_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 588.0
PYH2_k127_5068648_10 component of anaerobic K03533 - - 0.00000005132 61.0
PYH2_k127_5068648_11 RHS Repeat - - - 0.000002087 61.0
PYH2_k127_5068648_12 O-Antigen ligase - - - 0.00005834 56.0
PYH2_k127_5068648_2 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 454.0
PYH2_k127_5068648_3 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009989 273.0
PYH2_k127_5068648_4 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000004033 228.0
PYH2_k127_5068648_5 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000002799 214.0
PYH2_k127_5068648_6 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.000000000000000000000000000000000000000000002706 177.0
PYH2_k127_5068648_7 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000001525 171.0
PYH2_k127_5068648_8 oxidoreductase activity, acting on diphenols and related substances as donors - - - 0.00000000004596 69.0
PYH2_k127_5068648_9 nitrate reductase molybdenum cofactor assembly chaperone K17052 - - 0.000000005574 58.0
PYH2_k127_5069458_0 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 390.0
PYH2_k127_5069458_1 - - - - 0.00000000000000000000000000000000000000000000000000000000005104 211.0
PYH2_k127_5069458_2 - - - - 0.00000000000000000000000000000000000000000000004896 175.0
PYH2_k127_5069458_3 - - - - 0.00001817 49.0
PYH2_k127_5092034_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000004857 200.0
PYH2_k127_5092034_1 Bacterial membrane protein, YfhO - - - 0.0000000000000000000000000000000000000000000004991 190.0
PYH2_k127_5092034_2 PFAM Prenyltransferase squalene oxidase - - - 0.0000000000000000000000000000000007713 142.0
PYH2_k127_5092034_3 methyltransferase - - - 0.0000000000000000000000000000004938 134.0
PYH2_k127_5092034_4 Domain of unknown function (DUF362) - - - 0.000000000005262 75.0
PYH2_k127_50988_0 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002634 578.0
PYH2_k127_50988_1 peptidase dimerisation domain protein K01295 - 3.4.17.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 321.0
PYH2_k127_50988_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001913 289.0
PYH2_k127_50988_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000003156 229.0
PYH2_k127_50988_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000004885 213.0
PYH2_k127_50988_5 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000001061 113.0
PYH2_k127_50988_6 Alpha-amylase domain K01182 - 3.2.1.10 0.0000002279 62.0
PYH2_k127_5099798_0 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 601.0
PYH2_k127_5099798_1 2-epimerase K16213 - 5.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 455.0
PYH2_k127_5099798_2 Immune inhibitor A peptidase M6 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002961 272.0
PYH2_k127_5099798_3 FG-GAP repeat - - - 0.0000000000000000000000000000000000000000000000000000000000002366 239.0
PYH2_k127_5099798_5 - - - - 0.00000000000000000002043 94.0
PYH2_k127_5099798_6 Regulatory protein, FmdB family - - - 0.000001952 55.0
PYH2_k127_5105540_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007636 584.0
PYH2_k127_5105540_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007752 269.0
PYH2_k127_5105540_2 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000004515 162.0
PYH2_k127_5105540_3 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.000000000000000009071 86.0
PYH2_k127_5105540_4 - - - - 0.0000000000000002846 84.0
PYH2_k127_5105540_5 - - - - 0.000000000000005861 76.0
PYH2_k127_5105540_6 - - - - 0.00000000001501 73.0
PYH2_k127_5114787_0 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 608.0
PYH2_k127_5114787_1 PhoPQ-activated pathogenicity-related protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 558.0
PYH2_k127_5114787_10 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00003745 46.0
PYH2_k127_5114787_2 lactate racemase activity K22373 - 5.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004832 553.0
PYH2_k127_5114787_3 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 511.0
PYH2_k127_5114787_4 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 430.0
PYH2_k127_5114787_5 DegT/DnrJ/EryC1/StrS aminotransferase family K12452,K13017 - 1.17.1.1,2.6.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 409.0
PYH2_k127_5114787_6 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 322.0
PYH2_k127_5114787_7 oxidoreductase activity, acting on CH-OH group of donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 317.0
PYH2_k127_5114787_8 PFAM periplasmic binding protein LacI transcriptional regulator K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008787 316.0
PYH2_k127_5114787_9 tagaturonate epimerase K21619 - 5.1.2.7 0.000000000000000000000000000000000000000000000000000003236 194.0
PYH2_k127_511499_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009842 402.0
PYH2_k127_511499_1 surface antigen variable number - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 377.0
PYH2_k127_511499_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004173 307.0
PYH2_k127_511499_3 PFAM response regulator receiver K07665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005922 272.0
PYH2_k127_511499_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000004879 253.0
PYH2_k127_511499_5 ZIP Zinc transporter K07238,K11021,K16267 - - 0.0000000000000000000000000000000000000000000000000000000000001471 220.0
PYH2_k127_511499_6 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000003189 133.0
PYH2_k127_511499_7 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000001446 113.0
PYH2_k127_511499_8 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.00000000000000000005662 98.0
PYH2_k127_511499_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0008002 42.0
PYH2_k127_5117735_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 449.0
PYH2_k127_5117735_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 338.0
PYH2_k127_5117735_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 344.0
PYH2_k127_5117735_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000001078 236.0
PYH2_k127_5117735_4 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000004418 192.0
PYH2_k127_5117735_5 Membrane K08988 - - 0.00000000000000000000000000000002376 140.0
PYH2_k127_5117735_6 Membrane - - - 0.00000000000000000000001471 108.0
PYH2_k127_5117735_7 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000000108 91.0
PYH2_k127_5117735_8 Pilus assembly protein PilX K02673 - - 0.000003628 59.0
PYH2_k127_5135992_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001158 270.0
PYH2_k127_5135992_1 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000002092 184.0
PYH2_k127_5135992_2 GGDEF FHA domain protein - - - 0.0000000007434 72.0
PYH2_k127_5136195_0 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009823 363.0
PYH2_k127_5136195_1 - - - - 0.0005313 51.0
PYH2_k127_5142779_0 Alpha-L-fucosidase C-terminal domain K01206 - 3.2.1.51 1.046e-201 638.0
PYH2_k127_5142779_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004425 406.0
PYH2_k127_5142779_2 phosphoprotein phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 340.0
PYH2_k127_5142779_3 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000003679 234.0
PYH2_k127_5143341_0 Aldehyde dehydrogenase family K00132 - 1.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 541.0
PYH2_k127_5143341_1 enterobactin catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004824 332.0
PYH2_k127_5143341_10 Protein of unknown function (DUF1015) - - - 0.0000001062 55.0
PYH2_k127_5143341_2 ethanolamine catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 310.0
PYH2_k127_5143341_3 ethanolamine catabolic process K04024 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 299.0
PYH2_k127_5143341_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 GO:0003674,GO:0003824,GO:0004139,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016052,GO:0016829,GO:0016830,GO:0016832,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 4.1.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006709 285.0
PYH2_k127_5143341_5 galactose-6-phosphate isomerase activity K00761,K01808 - 2.4.2.9,5.3.1.6 0.0000000000000000000000000000000000000000000000005196 182.0
PYH2_k127_5143341_6 ethanolamine catabolic process K04027 - - 0.0000000000000000000000000000000000000002449 151.0
PYH2_k127_5143341_7 Ethanolamine utilisation protein EutN/carboxysome K04028 - - 0.00000000000000000000000001317 114.0
PYH2_k127_5143341_8 Ethanolamine utilisation protein EutN/carboxysome K04028 GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0033554,GO:0050896,GO:0051716 - 0.00000000000000006178 85.0
PYH2_k127_5143341_9 Ethanolamine utilization protein EutN carboxysome structural protein Ccml K04028 - - 0.000000012 60.0
PYH2_k127_5148576_0 Glycosyl hydrolase family 16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 294.0
PYH2_k127_5148576_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004845 284.0
PYH2_k127_5148576_2 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000006816 179.0
PYH2_k127_5148576_4 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000001624 146.0
PYH2_k127_5148576_5 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000002145 126.0
PYH2_k127_5148576_6 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000005333 116.0
PYH2_k127_5148576_7 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.000001117 52.0
PYH2_k127_5149346_0 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 373.0
PYH2_k127_5149346_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004539 237.0
PYH2_k127_5149346_2 - - - - 0.00000000000000001621 84.0
PYH2_k127_5149346_3 - - - - 0.0008668 42.0
PYH2_k127_5161463_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 570.0
PYH2_k127_5161463_1 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 367.0
PYH2_k127_5161463_2 PFAM oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 326.0
PYH2_k127_5161463_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000001033 213.0
PYH2_k127_5161463_4 Putative regulatory protein - - - 0.00000000000000000000000000000000005821 137.0
PYH2_k127_5161463_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0009065 44.0
PYH2_k127_5174871_0 PFAM peptidase K01284,K01414 - 3.4.15.5,3.4.24.70 4.615e-259 818.0
PYH2_k127_5174871_1 Major Facilitator Superfamily K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007538 509.0
PYH2_k127_5174871_10 Thermophilic metalloprotease (M29) K19689 - - 0.000000000001227 68.0
PYH2_k127_5174871_11 Transcriptional regulatory protein, C terminal K02483 - - 0.00003242 49.0
PYH2_k127_5174871_2 Two component regulator propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 451.0
PYH2_k127_5174871_3 Glycosyl hydrolase family 20, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 358.0
PYH2_k127_5174871_4 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001798 333.0
PYH2_k127_5174871_5 glycoside hydrolase family 2, TIM barrel K01192 - 3.2.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 343.0
PYH2_k127_5174871_6 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005567 273.0
PYH2_k127_5174871_7 Squalene phytoene synthase K00801 - 2.5.1.21 0.000000000000000000000000000000000000000000000000000000000000000000001232 248.0
PYH2_k127_5174871_8 NAD dependent epimerase dehydratase family protein K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000001016 231.0
PYH2_k127_5174871_9 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000002958 181.0
PYH2_k127_5180913_0 AcrB/AcrD/AcrF family K11326 - - 0.0 1384.0
PYH2_k127_5180913_1 Belongs to the IlvD Edd family K22396 - 4.2.1.82 8.135e-273 853.0
PYH2_k127_5180913_10 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 392.0
PYH2_k127_5180913_11 gluconate transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 374.0
PYH2_k127_5180913_12 Sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 366.0
PYH2_k127_5180913_13 and related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 357.0
PYH2_k127_5180913_14 efflux transmembrane transporter activity K15725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 339.0
PYH2_k127_5180913_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 340.0
PYH2_k127_5180913_16 Methane oxygenase PmoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 313.0
PYH2_k127_5180913_17 Protein of unknown function (DUF4127) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 320.0
PYH2_k127_5180913_18 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 306.0
PYH2_k127_5180913_19 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 296.0
PYH2_k127_5180913_2 Hydantoinase/oxoprolinase - - - 1.161e-241 769.0
PYH2_k127_5180913_20 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005772 296.0
PYH2_k127_5180913_21 Trehalose utilisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003397 246.0
PYH2_k127_5180913_22 GntP family permease K03299 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008963 240.0
PYH2_k127_5180913_23 Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) K01788 - 5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000001687 243.0
PYH2_k127_5180913_24 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000001625 218.0
PYH2_k127_5180913_25 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.000000000000000000000000000000000000000000000000007118 194.0
PYH2_k127_5180913_26 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.0000000000000000000000000000000000004231 143.0
PYH2_k127_5180913_27 Belongs to the ComB family K05979 - 3.1.3.71 0.0000000000000000000000000000000000005379 148.0
PYH2_k127_5180913_29 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000519 93.0
PYH2_k127_5180913_3 SAF K01708 - 4.2.1.42 5.114e-233 730.0
PYH2_k127_5180913_30 Putative modulator of DNA gyrase K03592 - - 0.00000000000006769 73.0
PYH2_k127_5180913_31 PFAM Rv0623 family protein transcription factor K19687 - - 0.00000000000006798 74.0
PYH2_k127_5180913_32 - - - - 0.000000000008134 70.0
PYH2_k127_5180913_33 Putative modulator of DNA gyrase K03592 - - 0.0002207 45.0
PYH2_k127_5180913_4 succinate dehydrogenase - - - 9.887e-226 710.0
PYH2_k127_5180913_5 beta-galactosidase activity K01179,K01190,K12308 - 3.2.1.23,3.2.1.4 6.426e-197 639.0
PYH2_k127_5180913_6 PFAM FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 485.0
PYH2_k127_5180913_7 ADP-glyceromanno-heptose 6-epimerase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006348 418.0
PYH2_k127_5180913_8 Ig domain protein group 2 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 415.0
PYH2_k127_5180913_9 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 396.0
PYH2_k127_5186098_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000006189 103.0
PYH2_k127_5186098_1 peptidase activity, acting on L-amino acid peptides K07004,K09955 - - 0.0005519 54.0
PYH2_k127_5188341_0 - - - - 0.000000000000000000000000000000000000000000000003411 190.0
PYH2_k127_5188341_1 Elongation factor SelB, winged helix K03833 - - 0.0000000000000000000000000001326 123.0
PYH2_k127_5188341_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000021 64.0
PYH2_k127_5188563_0 Domain of unknown function (DUF3492) K21011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 535.0
PYH2_k127_5188563_1 Putative exopolysaccharide Exporter (EPS-E) K21012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 462.0
PYH2_k127_5188563_10 PFAM TM1410 hypothetical-related protein K21006 - - 0.00001125 51.0
PYH2_k127_5188563_2 chaperone-mediated protein folding K11935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 374.0
PYH2_k127_5188563_3 Gaf domain K02584,K07713,K11908,K12266,K15836,K21009,K21405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 356.0
PYH2_k127_5188563_4 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000000002908 215.0
PYH2_k127_5188563_5 peptidyl-tyrosine sulfation K21010 - - 0.0000000000000000000000000000000000000000000000001344 191.0
PYH2_k127_5188563_6 domain, Protein K01674,K03646 - 4.2.1.1 0.00000000000000000000000000006528 132.0
PYH2_k127_5188563_7 - - - - 0.00000000001076 70.0
PYH2_k127_5188563_8 Type IV pilus assembly - - - 0.0000000000384 72.0
PYH2_k127_5212302_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 516.0
PYH2_k127_5212302_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000005694 61.0
PYH2_k127_5218008_0 serine-type peptidase activity K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 319.0
PYH2_k127_5218008_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000002268 139.0
PYH2_k127_5232611_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 580.0
PYH2_k127_5232611_1 serine-type endopeptidase activity K04771,K07126 - 3.4.21.107 0.000000000009004 76.0
PYH2_k127_5241708_0 Carboxypeptidase regulatory-like domain - - - 0.0 1364.0
PYH2_k127_5251771_0 Sugar (and other) transporter - - - 2.524e-202 636.0
PYH2_k127_5251771_1 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004515 333.0
PYH2_k127_5251771_2 Histidine kinase HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007182 349.0
PYH2_k127_5251771_3 His Kinase A (phosphoacceptor) domain K02484 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000009896 238.0
PYH2_k127_5251771_4 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) - - - 0.00000000000000000001801 101.0
PYH2_k127_5251771_5 PFAM response regulator receiver - - - 0.00000000000000242 82.0
PYH2_k127_5251771_6 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000007869 71.0
PYH2_k127_5251771_7 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000001436 58.0
PYH2_k127_5266597_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 6.304e-262 827.0
PYH2_k127_5266597_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 620.0
PYH2_k127_5266597_10 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000672 138.0
PYH2_k127_5266597_11 exo-alpha-(2->6)-sialidase activity K05989 - 3.2.1.40 0.000000000000000000001222 96.0
PYH2_k127_5266597_12 Belongs to the 'phage' integrase family - - - 0.000000000000000001796 99.0
PYH2_k127_5266597_13 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000000009903 86.0
PYH2_k127_5266597_14 Protein of unknown function (DUF721) - - - 0.0000003758 55.0
PYH2_k127_5266597_15 5'-nucleotidase, C-terminal domain K11751 - 3.1.3.5,3.6.1.45 0.000001239 59.0
PYH2_k127_5266597_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000643 388.0
PYH2_k127_5266597_3 Glycosyl Hydrolase Family 88 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 373.0
PYH2_k127_5266597_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 365.0
PYH2_k127_5266597_5 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007134 313.0
PYH2_k127_5266597_6 AIR carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 308.0
PYH2_k127_5266597_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001232 280.0
PYH2_k127_5266597_8 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000008206 245.0
PYH2_k127_5266597_9 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000005536 179.0
PYH2_k127_5278335_0 serine threonine protein kinase K00870,K12132 - 2.7.1.37,2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 438.0
PYH2_k127_5278335_1 - - - - 0.00000000000000000000000000000000000000003127 162.0
PYH2_k127_5278335_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000001495 126.0
PYH2_k127_5278335_3 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000001079 107.0
PYH2_k127_5280628_0 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000002884 194.0
PYH2_k127_5280628_1 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000003928 121.0
PYH2_k127_5280628_2 protein N-acetylglucosaminyltransferase activity - - - 0.000000009478 66.0
PYH2_k127_5295289_0 Integrase core domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 474.0
PYH2_k127_5295289_1 Transposase - - - 0.000000000000000000000000000000000000768 145.0
PYH2_k127_5302806_0 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 614.0
PYH2_k127_5302806_1 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501 - 3.5.5.1 0.000000000000000000000005637 104.0
PYH2_k127_53202_0 hydrolase activity, acting on glycosyl bonds - - - 1.434e-203 659.0
PYH2_k127_53202_1 Belongs to the glycosyl hydrolase 32 family K01212,K03332 - 3.2.1.65,3.2.1.80 0.000001686 51.0
PYH2_k127_53202_2 - - - - 0.0003797 52.0
PYH2_k127_5324675_0 NAD(P)H-binding K01710,K01784,K21211 - 4.2.1.46,5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 374.0
PYH2_k127_5324675_1 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 269.0
PYH2_k127_5324675_2 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000001033 189.0
PYH2_k127_5324675_3 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000002298 186.0
PYH2_k127_5324675_4 PFAM glycosyl transferase family 39 - - - 0.000000000000000000003634 106.0
PYH2_k127_535443_0 Belongs to the purine-cytosine permease (2.A.39) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 504.0
PYH2_k127_535443_1 protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007684 484.0
PYH2_k127_535443_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 410.0
PYH2_k127_535443_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 325.0
PYH2_k127_535443_4 PFAM NAD binding domain of 6-phosphogluconate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000001056 201.0
PYH2_k127_535443_5 chlorophyll binding - - - 0.00000000006855 72.0
PYH2_k127_535443_6 G5 - - - 0.000000003839 64.0
PYH2_k127_535443_7 Periplasmic or secreted lipoprotein - - - 0.00001617 55.0
PYH2_k127_535443_8 chemotaxis K03406,K05874 - - 0.0000932 53.0
PYH2_k127_5354747_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 - 5.99.1.3 6.023e-198 637.0
PYH2_k127_5354747_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 598.0
PYH2_k127_5366112_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008715 555.0
PYH2_k127_5366112_1 nuclease activity - - - 0.0000000000000000000000000000000000000281 149.0
PYH2_k127_5366112_2 NHL repeat - - - 0.000000000000000000000000000002187 142.0
PYH2_k127_5366112_3 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000000002793 85.0
PYH2_k127_538169_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000004508 247.0
PYH2_k127_538169_1 Pfam:N_methyl_2 - - - 0.0000000002168 68.0
PYH2_k127_5389032_0 MGS-like domain K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 572.0
PYH2_k127_5389032_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 579.0
PYH2_k127_5389032_10 Cold-Shock Protein K03704 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000003718 104.0
PYH2_k127_5389032_11 - - - - 0.0000000000000000001496 95.0
PYH2_k127_5389032_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008998 483.0
PYH2_k127_5389032_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 387.0
PYH2_k127_5389032_4 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 302.0
PYH2_k127_5389032_5 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006755 267.0
PYH2_k127_5389032_6 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000001202 252.0
PYH2_k127_5389032_7 O-Antigen ligase K02847 - - 0.00000000000000000000000000000000000000000000006261 192.0
PYH2_k127_5389032_8 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000005407 138.0
PYH2_k127_5389032_9 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000001516 121.0
PYH2_k127_5407368_0 Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family K02100 GO:0003674,GO:0005215,GO:0005351,GO:0005402,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008324,GO:0008643,GO:0015075,GO:0015077,GO:0015078,GO:0015144,GO:0015291,GO:0015293,GO:0015294,GO:0015295,GO:0015318,GO:0015672,GO:0016020,GO:0022804,GO:0022857,GO:0022890,GO:0034219,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 469.0
PYH2_k127_5407368_1 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009977 463.0
PYH2_k127_5407368_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 450.0
PYH2_k127_5407368_3 alpha beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004079 280.0
PYH2_k127_5407368_4 PFAM Uncharacterised BCR, COG1649 - - - 0.0000000000000000000000003863 106.0
PYH2_k127_5407368_5 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000005594 76.0
PYH2_k127_5407368_6 PFAM Metal-dependent phosphohydrolase, HD K06950 - - 0.0000005313 61.0
PYH2_k127_5407368_7 Tetratricopeptide repeat - - - 0.000006199 58.0
PYH2_k127_5407368_8 Transglycosylase-like domain K21687 - - 0.00007298 56.0
PYH2_k127_54257_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 4.596e-293 917.0
PYH2_k127_54257_1 PFAM Aminotransferase class I and II K10907 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 514.0
PYH2_k127_54257_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 409.0
PYH2_k127_54257_3 Transglycosylase SLT domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000003026 258.0
PYH2_k127_54257_4 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000004014 171.0
PYH2_k127_54257_5 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000004171 119.0
PYH2_k127_54257_6 Glycosyl transferase family 2 - - - 0.000000000000000000001788 104.0
PYH2_k127_54257_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000003695 102.0
PYH2_k127_54257_8 nuclear chromosome segregation - - - 0.00000000001807 77.0
PYH2_k127_54257_9 Methyltransferase type 11 - - - 0.00000002277 64.0
PYH2_k127_5443096_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 316.0
PYH2_k127_5443096_1 Amino acid adenylation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006408 265.0
PYH2_k127_5458701_0 Uncharacterised conserved protein (DUF2156) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004446 350.0
PYH2_k127_5458701_1 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005736 299.0
PYH2_k127_5458701_2 peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002084 237.0
PYH2_k127_5458701_3 transport - - - 0.000000000000000000000000000000000000000000000000000000002811 201.0
PYH2_k127_5458701_4 HEPN domain K07076 - - 0.000000000000000000008461 99.0
PYH2_k127_5458701_5 SNARE associated Golgi protein - GO:0000003,GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0032505,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.0000000000000001669 94.0
PYH2_k127_5458701_6 nucleotidyltransferase activity K17882 - - 0.000001606 59.0
PYH2_k127_5458701_7 PFAM alpha beta hydrolase K06889,K07397 - - 0.0007178 51.0
PYH2_k127_546878_0 Phosphoesterase family - - - 3.23e-273 867.0
PYH2_k127_546878_1 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 2.795e-256 796.0
PYH2_k127_546878_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 568.0
PYH2_k127_546878_3 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 312.0
PYH2_k127_546878_4 - - - - 0.0000000000000000000000000000000000006533 145.0
PYH2_k127_546878_5 helix_turn_helix, cAMP Regulatory protein K10914,K21828 - - 0.000000000000000001875 94.0
PYH2_k127_5481824_0 Glycosyl hydrolase family 20, domain 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 614.0
PYH2_k127_5481824_1 Peptidase family M20/M25/M40 K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 464.0
PYH2_k127_5481824_2 Addiction module toxin RelE StbE family - - - 0.00000000000000000003323 93.0
PYH2_k127_5481824_3 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000002244 79.0
PYH2_k127_5499181_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 468.0
PYH2_k127_5499181_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002982 278.0
PYH2_k127_5499181_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000007074 123.0
PYH2_k127_5499181_3 - - - - 0.000000000000000000000005181 106.0
PYH2_k127_5499181_4 VanZ like family - - - 0.00000000000002527 78.0
PYH2_k127_5499181_5 Modulates RecA activity K03565 - - 0.0000000299 62.0
PYH2_k127_5525383_0 Histidine kinase HAMP K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 318.0
PYH2_k127_5529908_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 2.868e-281 882.0
PYH2_k127_5529908_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 3.789e-239 766.0
PYH2_k127_5529908_10 - - - - 0.000008735 54.0
PYH2_k127_5529908_2 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 607.0
PYH2_k127_5529908_3 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 415.0
PYH2_k127_5529908_4 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 416.0
PYH2_k127_5529908_5 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 343.0
PYH2_k127_5529908_6 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004638 289.0
PYH2_k127_5529908_7 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000009722 244.0
PYH2_k127_5529908_8 4Fe-4S ferredoxin, iron-sulfur binding - - - 0.00000000000000000000000000000000000000000000000000000001384 207.0
PYH2_k127_5529908_9 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000000000000000000000000001386 180.0
PYH2_k127_5537085_0 Sodium:sulfate symporter transmembrane region K03319 - - 1.657e-197 625.0
PYH2_k127_5537085_1 Collagenase K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 591.0
PYH2_k127_5537085_2 OsmC-like protein - - - 0.00000000000000000000000000000000000000001791 157.0
PYH2_k127_5558684_0 Belongs to the glycosyl hydrolase 3 family K05349,K17641 - 3.2.1.21 6.282e-220 718.0
PYH2_k127_5558684_1 PFAM Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006747 322.0
PYH2_k127_5558684_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.0000000000000000000000000000367 124.0
PYH2_k127_5558684_3 Allophanate hydrolase subunit 2 K06350 - - 0.00000000000000000003606 92.0
PYH2_k127_55670_0 Carboxypeptidase regulatory-like domain - - - 2.37e-322 1023.0
PYH2_k127_55670_1 peptidoglycan glycosyltransferase activity K03588,K05364,K05837 GO:0002682,GO:0002684,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009605,GO:0009607,GO:0009987,GO:0035821,GO:0043207,GO:0044003,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048583,GO:0048584,GO:0050776,GO:0050778,GO:0050789,GO:0050896,GO:0051301,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0052031,GO:0052173,GO:0052200,GO:0052255,GO:0052552,GO:0052553,GO:0052555,GO:0052556,GO:0052564,GO:0052572,GO:0065007,GO:0075136 - 7.907e-287 917.0
PYH2_k127_55670_10 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000001601 227.0
PYH2_k127_55670_11 PAS fold - - - 0.00000000000000000000000000000000000000000000009656 190.0
PYH2_k127_55670_12 histone H2A K63-linked ubiquitination K02283 - - 0.0000000000000000000000000000000000000000000005769 179.0
PYH2_k127_55670_13 histone H2A K63-linked ubiquitination K01768,K03220,K10914 - 4.6.1.1 0.00000000000000000000000000000000000000000003058 171.0
PYH2_k127_55670_14 Methyltransferase - - - 0.000000000000000000000000000000000000006371 154.0
PYH2_k127_55670_15 Cytochrome c K02720 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0042651,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.00000000000000000000000000000004753 132.0
PYH2_k127_55670_16 FMN-dependent dehydrogenase K16422 - 1.1.3.46 0.0000000000000000000000000001273 123.0
PYH2_k127_55670_17 - - - - 0.0000000000000000000000000015 115.0
PYH2_k127_55670_18 lipolytic protein G-D-S-L family - - - 0.00000007776 64.0
PYH2_k127_55670_2 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 506.0
PYH2_k127_55670_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005531 437.0
PYH2_k127_55670_4 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 419.0
PYH2_k127_55670_5 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 405.0
PYH2_k127_55670_6 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 378.0
PYH2_k127_55670_7 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 302.0
PYH2_k127_55670_8 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000002627 235.0
PYH2_k127_55670_9 PFAM FMN-dependent alpha-hydroxy acid dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000002173 224.0
PYH2_k127_5572119_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1147.0
PYH2_k127_5572119_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 338.0
PYH2_k127_5572119_2 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
PYH2_k127_5572119_3 TIGRFAM deoxyguanosinetriphosphate triphosphohydrolase K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002755 267.0
PYH2_k127_5572119_4 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000002115 248.0
PYH2_k127_5572119_5 translation release factor activity K15034 GO:0003674,GO:0003676,GO:0003723,GO:0003747,GO:0003824,GO:0004045,GO:0005488,GO:0006412,GO:0006414,GO:0006415,GO:0006417,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016043,GO:0016150,GO:0016787,GO:0016788,GO:0019222,GO:0019538,GO:0022411,GO:0031323,GO:0031326,GO:0032268,GO:0032984,GO:0034248,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0052689,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072344,GO:0080090,GO:0097159,GO:0140098,GO:0140101,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2000112 - 0.00000000000000000000000002998 113.0
PYH2_k127_5572119_6 SMART phosphoesterase PHP domain protein - - - 0.0000000003289 70.0
PYH2_k127_5598127_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009285 294.0
PYH2_k127_5598127_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000000000001376 143.0
PYH2_k127_5598127_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.0003961 46.0
PYH2_k127_5610299_0 OPT oligopeptide transporter protein - - - 1.7e-316 981.0
PYH2_k127_5610299_1 pfam yhs - - - 0.000000000009821 70.0
PYH2_k127_5610299_2 Domain of unknown function (DUF362) - - - 0.000001696 50.0
PYH2_k127_561465_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 617.0
PYH2_k127_561465_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 458.0
PYH2_k127_561465_10 EamA-like transporter family - - - 0.00000000000000001071 88.0
PYH2_k127_561465_11 Diguanylate cyclase - - - 0.000009552 57.0
PYH2_k127_561465_12 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0005238 51.0
PYH2_k127_561465_13 Alpha/beta hydrolase family K06889 - - 0.0005238 51.0
PYH2_k127_561465_2 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 413.0
PYH2_k127_561465_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 GO:0008150,GO:0040007 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 393.0
PYH2_k127_561465_4 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 379.0
PYH2_k127_561465_5 Epimerase dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 301.0
PYH2_k127_561465_6 4-phosphoerythronate dehydrogenase activity K03473 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0033711,GO:0034641,GO:0036001,GO:0036094,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055114,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.290 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 296.0
PYH2_k127_561465_7 YdjC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002426 283.0
PYH2_k127_561465_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000001949 256.0
PYH2_k127_561465_9 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000001249 146.0
PYH2_k127_5615757_0 Radical SAM - - - 4.678e-217 692.0
PYH2_k127_5615757_1 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008377 623.0
PYH2_k127_5615757_10 Putative adhesin - - - 0.00000000000002355 84.0
PYH2_k127_5615757_11 Putative zinc-finger K03088 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000008906 80.0
PYH2_k127_5615757_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 563.0
PYH2_k127_5615757_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 463.0
PYH2_k127_5615757_4 PFAM von Willebrand factor type A K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001703 267.0
PYH2_k127_5615757_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000000000000000001627 177.0
PYH2_k127_5615757_6 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000003373 170.0
PYH2_k127_5615757_7 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000003865 142.0
PYH2_k127_5615757_8 23S rRNA-intervening sequence protein - - - 0.00000000000000000000008488 103.0
PYH2_k127_5615757_9 DNA-templated transcription, initiation K03088 - - 0.000000000000000000233 96.0
PYH2_k127_5632130_0 TIGRFAM Polyphosphate nucleotide phosphotransferase, PPK2 K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 405.0
PYH2_k127_5632130_1 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 343.0
PYH2_k127_5632130_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000006864 239.0
PYH2_k127_5643183_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 8.403e-236 745.0
PYH2_k127_5643183_1 oligopeptide transport K03305 - - 1.692e-234 734.0
PYH2_k127_5643183_11 cytokinin biosynthetic process K06966 - 3.2.2.10 0.00000000000000000000000002855 115.0
PYH2_k127_5643183_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000006978 78.0
PYH2_k127_5643183_13 Peptidase family M3 K01284 GO:0003674,GO:0003824,GO:0004180,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.15.5 0.00001888 50.0
PYH2_k127_5643183_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 593.0
PYH2_k127_5643183_3 Thermophilic metalloprotease (M29) K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 527.0
PYH2_k127_5643183_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007678 495.0
PYH2_k127_5643183_5 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001867 437.0
PYH2_k127_5643183_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 323.0
PYH2_k127_5643183_8 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000491 207.0
PYH2_k127_5657801_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00161,K00162,K11381 - 1.2.4.1,1.2.4.4 0.0 1228.0
PYH2_k127_5657801_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 602.0
PYH2_k127_5657801_10 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000634 219.0
PYH2_k127_5657801_11 ABC-type nitrate sulfonate bicarbonate transport system permease component K02050 - - 0.0000000000000000000000000000000000000002591 160.0
PYH2_k127_5657801_12 Phospholipid N-methyltransferase - - - 0.0000000000000000000000000000000000005484 147.0
PYH2_k127_5657801_13 DeoR C terminal sensor domain - - - 0.00000000000000000000000000000000002879 145.0
PYH2_k127_5657801_2 PFAM Short-chain dehydrogenase reductase SDR K00068 - 1.1.1.140 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 587.0
PYH2_k127_5657801_3 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 509.0
PYH2_k127_5657801_4 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 464.0
PYH2_k127_5657801_5 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 454.0
PYH2_k127_5657801_6 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 331.0
PYH2_k127_5657801_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 300.0
PYH2_k127_5657801_8 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006125 282.0
PYH2_k127_5657801_9 Inositol monophosphatase family - - - 0.00000000000000000000000000000000000000000000000000000000000006222 223.0
PYH2_k127_5662806_0 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 346.0
PYH2_k127_5662806_1 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000002402 108.0
PYH2_k127_5662806_2 DNA-binding regulatory protein K03088 - - 0.000000000006537 75.0
PYH2_k127_5664891_0 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 476.0
PYH2_k127_5664891_1 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000001524 176.0
PYH2_k127_5664891_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000008382 188.0
PYH2_k127_5668252_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1247.0
PYH2_k127_5668252_1 Galactokinase galactose-binding signature K00849 - 2.7.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001943 387.0
PYH2_k127_5668252_2 mannitol metabolic process K00009 - 1.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 374.0
PYH2_k127_5668252_3 Psort location Cytoplasmic, score K00008 - 1.1.1.14 0.0000000000000000000000000000000000001729 148.0
PYH2_k127_5668252_4 23S rRNA-intervening sequence protein - - - 0.000000000000000000000001678 107.0
PYH2_k127_5675563_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.579e-267 844.0
PYH2_k127_5675563_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 7.562e-257 804.0
PYH2_k127_5675563_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007236 424.0
PYH2_k127_5675563_3 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 426.0
PYH2_k127_5675563_4 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 300.0
PYH2_k127_5675563_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001165 265.0
PYH2_k127_5675563_6 Protein of unknown function (DUF1638) - - - 0.0000000000000000000000000000000000000000000000004707 184.0
PYH2_k127_5675563_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000002468 160.0
PYH2_k127_5676771_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 4.406e-200 631.0
PYH2_k127_5676771_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000001664 241.0
PYH2_k127_5676771_2 dCMP deaminase activity K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000000589 216.0
PYH2_k127_5676771_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.0000000000000000000000000000000000000000000005016 173.0
PYH2_k127_5676771_4 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000001143 171.0
PYH2_k127_5676771_5 dephospho-CoA kinase activity - - - 0.00000000000000000000000000000000001546 148.0
PYH2_k127_5676771_6 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000001162 139.0
PYH2_k127_5676771_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000005889 121.0
PYH2_k127_5676771_8 CYTH K05873 - 4.6.1.1 0.0000000000000000000000002621 113.0
PYH2_k127_5676771_9 Methyltransferase type 11 - - - 0.0000004275 60.0
PYH2_k127_5681129_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 557.0
PYH2_k127_5681129_1 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 550.0
PYH2_k127_5681129_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 386.0
PYH2_k127_5681129_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002785 384.0
PYH2_k127_5681129_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000004626 190.0
PYH2_k127_5682553_0 cobalamin binding K01647,K18997,K22491 - 2.3.3.1 0.00000000000000000000000000000000000000000000000001652 191.0
PYH2_k127_5682553_1 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.00000000000000000000005964 104.0
PYH2_k127_5682553_2 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0040007,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000005572 66.0
PYH2_k127_5682553_3 cobalamin binding K01647,K18997,K22491 - 2.3.3.1 0.0000000008652 61.0
PYH2_k127_5682553_4 Domain of unknown function (DUF4174) - - - 0.000000007603 59.0
PYH2_k127_5682553_5 Flavin containing amine oxidoreductase - - - 0.00009429 51.0
PYH2_k127_5683711_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 390.0
PYH2_k127_5683711_1 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000002186 216.0
PYH2_k127_5683711_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000001836 186.0
PYH2_k127_5683711_3 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000003532 109.0
PYH2_k127_5683711_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000003663 81.0
PYH2_k127_5683711_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000001167 65.0
PYH2_k127_5685043_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009334 271.0
PYH2_k127_5685043_1 Glucose dehydrogenase C-terminus - - - 0.00000000000000000000000000000000000000000008633 161.0
PYH2_k127_5685043_2 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000000000000000000000000000004381 121.0
PYH2_k127_5685043_3 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000003198 59.0
PYH2_k127_5698897_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 2.443e-307 950.0
PYH2_k127_570138_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 575.0
PYH2_k127_570138_1 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 486.0
PYH2_k127_570138_2 Cytochrome c K00425 - 1.10.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 292.0
PYH2_k127_570138_3 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000009552 201.0
PYH2_k127_570633_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 2.036e-298 924.0
PYH2_k127_570633_1 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 539.0
PYH2_k127_570633_2 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 323.0
PYH2_k127_570633_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 309.0
PYH2_k127_570633_4 Prolyl oligopeptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001158 269.0
PYH2_k127_570633_5 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001074 248.0
PYH2_k127_570633_6 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000000000000000001049 157.0
PYH2_k127_570633_7 COGs COG0680 Ni Fe-hydrogenase maturation factor K03605 - - 0.00000000000000000000000000000000000000001968 158.0
PYH2_k127_570633_8 PFAM HypF finger K04656 - - 0.000000000000000000000000000000506 124.0
PYH2_k127_570633_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000004784 82.0
PYH2_k127_5706371_0 PLP-dependent enzyme possibly involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003293 358.0
PYH2_k127_5706371_1 Nucleotidyl transferase K00966,K21210 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000002395 193.0
PYH2_k127_5706371_2 Cytidylyltransferase K07257 - - 0.000000000000000000000000000000000000002545 156.0
PYH2_k127_5706825_0 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000001232 113.0
PYH2_k127_5706825_1 23S rRNA-intervening sequence protein - - - 0.0000000000000000000009234 99.0
PYH2_k127_5714219_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 512.0
PYH2_k127_5714219_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 425.0
PYH2_k127_5714219_10 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000001331 176.0
PYH2_k127_5714219_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000005256 166.0
PYH2_k127_5714219_12 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.00000000000000000003039 93.0
PYH2_k127_5714219_13 amine dehydrogenase activity K21449 - - 0.00000000000000000003393 106.0
PYH2_k127_5714219_2 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 379.0
PYH2_k127_5714219_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 361.0
PYH2_k127_5714219_4 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000006657 228.0
PYH2_k127_5714219_5 oxidation-reduction process K18239,K18240 GO:0003674,GO:0003824,GO:0016787,GO:0016801,GO:0016803 3.3.2.13,4.1.3.40,4.1.3.45 0.00000000000000000000000000000000000000000000000000000002146 203.0
PYH2_k127_5714219_6 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000008644 202.0
PYH2_k127_5714219_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000001983 186.0
PYH2_k127_5714219_8 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000008692 183.0
PYH2_k127_5714219_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000003169 171.0
PYH2_k127_572536_0 PFAM Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 464.0
PYH2_k127_572536_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 444.0
PYH2_k127_572536_2 PFAM IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009062 269.0
PYH2_k127_572536_4 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0001601 48.0
PYH2_k127_5725809_0 alpha-galactosidase K07407 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 444.0
PYH2_k127_5725809_1 PFAM Uncharacterised BCR, COG1649 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 328.0
PYH2_k127_5725809_2 BON domain - - - 0.000000000000000000000000000000000000000000000000000000001739 208.0
PYH2_k127_5726816_0 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003899 302.0
PYH2_k127_5726816_1 Aminopeptidase K19701 - 3.4.11.10,3.4.11.6 0.0000000000004004 81.0
PYH2_k127_5726816_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000007112 48.0
PYH2_k127_5732374_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000002666 141.0
PYH2_k127_5732374_1 nuclease activity - - - 0.0000000000000000000000000000002005 127.0
PYH2_k127_5732374_10 - - - - 0.0002677 46.0
PYH2_k127_5732374_2 - - - - 0.00000000000000000000000000001129 122.0
PYH2_k127_5732374_3 Domain of unknown function (DUF4258) - - - 0.00000000000000000000000001087 115.0
PYH2_k127_5732374_4 Protein of unknown function (DUF433) - - - 0.00000000000000000000000004247 108.0
PYH2_k127_5732374_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000000000000000002154 98.0
PYH2_k127_5732374_8 - - - - 0.00000000001179 68.0
PYH2_k127_5732374_9 PFAM DUF218 domain - - - 0.0002197 47.0
PYH2_k127_5734414_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 9.368e-277 876.0
PYH2_k127_5734414_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K20810 - 3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 431.0
PYH2_k127_5734414_2 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 306.0
PYH2_k127_5741037_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.763e-303 943.0
PYH2_k127_5741037_1 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000006509 108.0
PYH2_k127_5754298_0 Mannosyl oligosaccharide glucosidase - - - 0.0 1275.0
PYH2_k127_5754298_1 peptidyl-tyrosine sulfation - - - 3.009e-288 899.0
PYH2_k127_5754298_10 - - - - 0.000000000000000000000004178 109.0
PYH2_k127_5754298_11 - - - - 0.0000000000000000005903 91.0
PYH2_k127_5754298_12 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000000001199 68.0
PYH2_k127_5754298_13 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000001424 59.0
PYH2_k127_5754298_2 domain protein - - - 1.689e-230 723.0
PYH2_k127_5754298_3 Alpha-L-fucosidase K01206 - 3.2.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 612.0
PYH2_k127_5754298_4 dipeptidyl-peptidase activity K06978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 614.0
PYH2_k127_5754298_5 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 601.0
PYH2_k127_5754298_6 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K08323 - 4.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000342 501.0
PYH2_k127_5754298_7 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 365.0
PYH2_k127_5754298_8 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003112 272.0
PYH2_k127_5754298_9 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000003584 130.0
PYH2_k127_5756386_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 7.269e-230 715.0
PYH2_k127_5756386_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003857 296.0
PYH2_k127_5757117_0 Domain of unknown function (DUF5107) - - - 8.187e-269 865.0
PYH2_k127_5757117_1 PFAM Major facilitator superfamily K02429 - - 7.752e-211 664.0
PYH2_k127_5757117_2 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000591 256.0
PYH2_k127_5757117_3 fructose-bisphosphate aldolase activity K01624,K08302 - 4.1.2.13,4.1.2.40 0.000000000000000000000000000000000000004697 153.0
PYH2_k127_5757117_4 nuclease activity - - - 0.000000000000000000000000000001389 125.0
PYH2_k127_5757117_5 PIN domain - - - 0.0000000000000000000001592 102.0
PYH2_k127_5757117_6 positive regulation of growth - GO:0006417,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0019222,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0034248,GO:0034250,GO:0040007,GO:0045727,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0080090,GO:2000112 - 0.0000000000002435 72.0
PYH2_k127_5757117_8 SPTR Glycoside hydrolase family 29 (Alpha-L-fucosidase) K01206 - 3.2.1.51 0.000000001637 60.0
PYH2_k127_5782331_0 TonB-dependent receptor - - - 3.744e-276 885.0
PYH2_k127_5782331_1 Domain of unknown function (DUF4091) - - - 2.286e-235 741.0
PYH2_k127_5782331_2 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 556.0
PYH2_k127_5782331_3 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009499 272.0
PYH2_k127_5782331_4 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 246.0
PYH2_k127_5800276_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1407.0
PYH2_k127_5800276_1 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 505.0
PYH2_k127_5800276_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001991 356.0
PYH2_k127_5800276_3 TonB-dependent receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005154 349.0
PYH2_k127_5800276_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000001078 209.0
PYH2_k127_5832706_0 Aldo/keto reductase family K07079 - - 0.00000001123 67.0
PYH2_k127_5846929_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 605.0
PYH2_k127_5846929_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008135 340.0
PYH2_k127_5848194_0 Domain of unknown function (DUF1998) K06877 - - 1.501e-299 938.0
PYH2_k127_5848194_1 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K11102 - - 1.389e-199 632.0
PYH2_k127_5848194_2 xaa-pro aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 514.0
PYH2_k127_5848194_3 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000000000000000000002091 220.0
PYH2_k127_5848194_4 - - - - 0.00000000000000000000000000000000000001858 149.0
PYH2_k127_5857942_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003021 481.0
PYH2_k127_5872473_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 355.0
PYH2_k127_5872473_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000002868 155.0
PYH2_k127_5872473_2 - K07283 - - 0.0000000000000000000000000000000000001431 149.0
PYH2_k127_5872473_3 Phage integrase family - - - 0.000000000000000000001385 100.0
PYH2_k127_5873633_0 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000002488 168.0
PYH2_k127_5873633_1 Flagellar basal body rod protein K02390 - - 0.0000000000000961 71.0
PYH2_k127_5873633_2 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000003034 53.0
PYH2_k127_5889326_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 550.0
PYH2_k127_5889326_1 transmembrane transporter activity K13021 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 497.0
PYH2_k127_5889326_2 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002456 493.0
PYH2_k127_5889326_3 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 355.0
PYH2_k127_5889326_4 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.00000000000000000000000000000000000009686 158.0
PYH2_k127_5889326_5 addiction module antidote protein HigA K21498 - - 0.00000000000000000000000000001001 121.0
PYH2_k127_5889326_6 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.00000000000000000000000000002832 120.0
PYH2_k127_5889711_0 Uncharacterized protein family (UPF0051) K09014 - - 4.572e-266 824.0
PYH2_k127_5889711_1 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004129 584.0
PYH2_k127_5889711_2 FeS assembly protein SufD K09015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 390.0
PYH2_k127_5889711_3 ABC transporter K09013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051186,GO:0071840 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009671 377.0
PYH2_k127_5889711_4 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000000000000251 211.0
PYH2_k127_5889711_5 Transcriptional regulator - - - 0.00000000000000000000000000000000001681 143.0
PYH2_k127_5889711_6 23S rRNA-intervening sequence protein - - - 0.0000003772 53.0
PYH2_k127_5908088_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 3.997e-211 685.0
PYH2_k127_5908088_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 332.0
PYH2_k127_5908088_10 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000001089 100.0
PYH2_k127_5908088_11 - - - - 0.00000000000000003609 85.0
PYH2_k127_5908088_12 anti-sigma factor - GO:0005575,GO:0016020 - 0.00000007595 62.0
PYH2_k127_5908088_13 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000006473 61.0
PYH2_k127_5908088_2 PFAM Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005541 273.0
PYH2_k127_5908088_3 S4 RNA-binding domain K06177,K06180 - 5.4.99.23,5.4.99.28,5.4.99.29 0.00000000000000000000000000000000000000000000000000000000000000004283 232.0
PYH2_k127_5908088_4 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000006915 216.0
PYH2_k127_5908088_5 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000505 207.0
PYH2_k127_5908088_6 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000889 180.0
PYH2_k127_5908088_8 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000009822 135.0
PYH2_k127_5908088_9 - - - - 0.00000000000000000000003039 105.0
PYH2_k127_593205_0 acetylesterase activity K15923 - 3.2.1.51 6.736e-265 837.0
PYH2_k127_593205_1 transport - - - 2.212e-240 767.0
PYH2_k127_593205_10 PFAM von Willebrand factor type A K07114 - - 0.00000000000000000006988 106.0
PYH2_k127_593205_11 Tetratricopeptide TPR_2 repeat protein - - - 0.00000005806 68.0
PYH2_k127_593205_12 Domain of unknown function (DUF4393) - - - 0.000003165 57.0
PYH2_k127_593205_2 PQQ-like domain - - - 6.52e-209 661.0
PYH2_k127_593205_3 WG containing repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007227 286.0
PYH2_k127_593205_4 ribonuclease inhibitor activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000001539 241.0
PYH2_k127_593205_5 Domain of unknown function (4846) - - - 0.00000000000000000000000000000000000000000000000000000000000000003834 235.0
PYH2_k127_593205_6 - - - - 0.000000000000000000000000000000000000000000000000002968 203.0
PYH2_k127_593205_7 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000005257 174.0
PYH2_k127_593205_8 Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) K00849 - 2.7.1.6 0.00000000000000000000000000000000043 152.0
PYH2_k127_593205_9 - - - - 0.000000000000000000008431 97.0
PYH2_k127_5937459_0 PFAM GCN5-related N-acetyltransferase K03824 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004567 259.0
PYH2_k127_5937459_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000002948 235.0
PYH2_k127_5937459_2 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000001254 213.0
PYH2_k127_5937459_3 LexA-binding, inner membrane-associated putative hydrolase - - - 0.00000000000000000000000000000000000000001708 159.0
PYH2_k127_5937459_4 - - - - 0.000000000000000000000000000000000000001053 151.0
PYH2_k127_5937459_5 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000004364 157.0
PYH2_k127_5937459_6 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000001341 63.0
PYH2_k127_5937459_7 aminopeptidase N - - - 0.00001289 56.0
PYH2_k127_5937860_0 COG2801 Transposase and inactivated derivatives K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 325.0
PYH2_k127_5937860_1 Helix-turn-helix domain K07497 - - 0.000000000000000000000000000000000005791 139.0
PYH2_k127_5943539_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 533.0
PYH2_k127_5943539_1 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 430.0
PYH2_k127_5943539_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000001355 104.0
PYH2_k127_5943539_11 Ribosomal L32p protein family K02911 - - 0.000000000000000003855 87.0
PYH2_k127_5943539_12 Tetratricopeptide repeat-like domain - - - 0.0000000000001566 81.0
PYH2_k127_5943539_13 - - - - 0.000002167 59.0
PYH2_k127_5943539_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 375.0
PYH2_k127_5943539_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 336.0
PYH2_k127_5943539_4 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 323.0
PYH2_k127_5943539_5 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 322.0
PYH2_k127_5943539_6 Transporter associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001128 250.0
PYH2_k127_5943539_7 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000001936 232.0
PYH2_k127_5943539_8 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000007233 119.0
PYH2_k127_5943539_9 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000001023 113.0
PYH2_k127_5978699_0 COG3119 Arylsulfatase A - - - 2.676e-200 634.0
PYH2_k127_5978699_1 PIN domain - - - 0.00000000000000000000000000000000000000003184 156.0
PYH2_k127_5978699_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000002136 151.0
PYH2_k127_5978699_3 - - - - 0.00002618 48.0
PYH2_k127_5991348_0 Aldehyde dehydrogenase family K00128 - 1.2.1.3 5.372e-221 697.0
PYH2_k127_5991348_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 309.0
PYH2_k127_5991348_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000002228 221.0
PYH2_k127_5991348_3 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000000000000000000000001657 147.0
PYH2_k127_6004152_0 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003415 249.0
PYH2_k127_6004152_1 PFAM Transposase, IS4-like - - - 0.00005495 48.0
PYH2_k127_6010226_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 2.319e-220 699.0
PYH2_k127_6013024_0 Prolyl oligopeptidase family - - - 3.983e-277 867.0
PYH2_k127_6013024_1 type VI secretion protein, EvpB VC_A0108 family K11900 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007234 318.0
PYH2_k127_6013024_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000009883 248.0
PYH2_k127_6013024_3 SCO1/SenC K07152,K08976 - - 0.00000000000000000000000000000000004305 139.0
PYH2_k127_6013024_4 - - - - 0.000000002311 61.0
PYH2_k127_6013471_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 344.0
PYH2_k127_6013471_1 - - - - 0.0000000000000000000000000000000000000000000000000000009985 196.0
PYH2_k127_6013471_2 PFAM DNA polymerase beta domain protein region K07075 - - 0.0000000000000000000000000006677 115.0
PYH2_k127_6013471_3 Protein of unknown function DUF86 - - - 0.0000000000000000000000007308 107.0
PYH2_k127_6017490_0 signal-transduction protein containing cAMP-binding and CBS domains K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 413.0
PYH2_k127_6017490_1 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000003795 111.0
PYH2_k127_6017490_2 Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000009667 115.0
PYH2_k127_6017490_3 Sigma-70, region 4 K03088 - - 0.0000000000000000000000006036 112.0
PYH2_k127_6017490_4 mRNA binding K07339 - - 0.00000000000000000001824 93.0
PYH2_k127_6017490_5 Carboxymuconolactone decarboxylase family - - - 0.0002689 46.0
PYH2_k127_6018052_0 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000001303 157.0
PYH2_k127_6018052_1 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000438 123.0
PYH2_k127_6018052_2 chlorophyll binding - - - 0.0000000000003481 78.0
PYH2_k127_6020460_0 Integrase core domain K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 478.0
PYH2_k127_6020460_1 Transposase - - - 0.000000000000000000000000000000002604 134.0
PYH2_k127_6020460_2 Multiple ankyrin repeats single kh domain-containing protein - - - 0.00002533 48.0
PYH2_k127_6020866_0 Carboxypeptidase regulatory-like domain - - - 3.027e-237 762.0
PYH2_k127_6020866_1 Inositol oxygenase K00469 - 1.13.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002352 446.0
PYH2_k127_6020866_2 - - - - 0.000000000000000000000005095 110.0
PYH2_k127_6020866_3 PIN domain K07064 - - 0.0000000007021 64.0
PYH2_k127_6022108_0 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 387.0
PYH2_k127_6022108_1 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000009239 175.0
PYH2_k127_6022108_2 Lysin motif - - - 0.00000000000000000000000000000000000000000000555 168.0
PYH2_k127_6022108_3 Aminotransferase K01845 - 5.4.3.8 0.00000000000000000000000000000000000000001439 161.0
PYH2_k127_6022108_4 PFAM Lanthionine synthetase - - - 0.0000000000000000000000000000000000001048 145.0
PYH2_k127_6022108_6 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000072 84.0
PYH2_k127_6022108_7 Phage derived protein Gp49-like (DUF891) - - - 0.000000000003488 68.0
PYH2_k127_6025181_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000001712 179.0
PYH2_k127_6025181_1 Polygalacturonase - - - 0.00000144 57.0
PYH2_k127_6030596_0 Conserved protein - - - 0.00000000000000000000000000000000000000000000000008 195.0
PYH2_k127_6032651_0 Hypothetical glycosyl hydrolase 6 - - - 0.0 1056.0
PYH2_k127_6032651_1 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 544.0
PYH2_k127_6032651_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009387 429.0
PYH2_k127_6032651_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 336.0
PYH2_k127_6032651_4 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004676 295.0
PYH2_k127_6032651_5 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000001653 231.0
PYH2_k127_6032651_6 PFAM periplasmic binding protein K02016 - - 0.00000000000000000000000000000000000000000000000000007477 199.0
PYH2_k127_6032651_7 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000001202 193.0
PYH2_k127_6032651_8 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000001048 142.0
PYH2_k127_6032651_9 peptidyl-prolyl isomerase K03769 - 5.2.1.8 0.00000000000000000000000001694 122.0
PYH2_k127_6061899_0 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667 - 4.1.99.1 5.936e-222 695.0
PYH2_k127_6061899_1 Acyl-homoserine-lactone synthase K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 515.0
PYH2_k127_6061899_10 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016491,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0052693,GO:0055086,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 310.0
PYH2_k127_6061899_11 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000118 291.0
PYH2_k127_6061899_12 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003688 285.0
PYH2_k127_6061899_13 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002945 282.0
PYH2_k127_6061899_14 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 GO:0003674,GO:0003824,GO:0004799,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0019637,GO:0019692,GO:0032259,GO:0034641,GO:0034654,GO:0042083,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046385,GO:0046483,GO:0055086,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003613 269.0
PYH2_k127_6061899_15 PFAM Glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000156 249.0
PYH2_k127_6061899_16 macromolecule localization K09690 - - 0.00000000000000000000000000000000000000000000000000000000000006764 223.0
PYH2_k127_6061899_17 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000000000005418 194.0
PYH2_k127_6061899_18 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000001526 179.0
PYH2_k127_6061899_19 O-antigen ligase like membrane protein - - - 0.00000000000000000000000000000000000000000741 173.0
PYH2_k127_6061899_2 Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 427.0
PYH2_k127_6061899_20 PFAM glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000000000001397 160.0
PYH2_k127_6061899_21 Putative esterase - - - 0.0000000000000000000000000000000000000215 156.0
PYH2_k127_6061899_22 BON domain - - - 0.0000000000000000000000000000000008824 145.0
PYH2_k127_6061899_23 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000158 131.0
PYH2_k127_6061899_3 Domain of unknown function (DUF1972) K12996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 416.0
PYH2_k127_6061899_4 Wzt C-terminal domain K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 406.0
PYH2_k127_6061899_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 378.0
PYH2_k127_6061899_6 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 396.0
PYH2_k127_6061899_7 NAD(P)H-binding K01784,K02473 - 5.1.3.2,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 341.0
PYH2_k127_6061899_8 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000356 328.0
PYH2_k127_6061899_9 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 321.0
PYH2_k127_6072263_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 448.0
PYH2_k127_6076912_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 605.0
PYH2_k127_6076912_1 PFAM sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007355 553.0
PYH2_k127_6076912_2 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 413.0
PYH2_k127_6076912_3 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 292.0
PYH2_k127_6076912_4 Transglycosylase K08307 - - 0.0000000000000000000000000000001451 140.0
PYH2_k127_6076912_6 (FHA) domain - - - 0.00000009602 64.0
PYH2_k127_6076912_7 cytochrome - - - 0.0003061 52.0
PYH2_k127_6085573_0 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 446.0
PYH2_k127_6085573_1 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000000000000000002385 233.0
PYH2_k127_6100580_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695,K03696 - - 0.0 1080.0
PYH2_k127_6100580_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.809e-319 994.0
PYH2_k127_6100580_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 409.0
PYH2_k127_6100580_3 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 329.0
PYH2_k127_6100580_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 308.0
PYH2_k127_6100580_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000009427 222.0
PYH2_k127_6100580_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000004263 220.0
PYH2_k127_6100580_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000005285 174.0
PYH2_k127_6100580_8 PFAM phosphatidate cytidylyltransferase K00981 - 2.7.7.41 0.00000000000000000000000000000000000006261 153.0
PYH2_k127_6100580_9 Memo-like protein K06990 - - 0.0000000000000000000000000000009978 123.0
PYH2_k127_6101841_0 TonB-dependent receptor - - - 4.344e-261 845.0
PYH2_k127_6101841_1 glycoside hydrolase family 2 sugar binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 584.0
PYH2_k127_6101841_10 Glycosyl hydrolase family 2, sugar binding domain protein - - - 0.00000000000009449 76.0
PYH2_k127_6101841_12 TPR repeat - - - 0.00000003103 65.0
PYH2_k127_6101841_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 410.0
PYH2_k127_6101841_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008142 372.0
PYH2_k127_6101841_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 336.0
PYH2_k127_6101841_5 IclR helix-turn-helix domain K10439 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 313.0
PYH2_k127_6101841_6 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 318.0
PYH2_k127_6101841_7 transcription factor binding K02584,K11914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000148 303.0
PYH2_k127_6101841_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000005362 220.0
PYH2_k127_6101841_9 Sulfatase-modifying factor enzyme 1 K18912 - 1.14.99.50 0.0000000000000000000000000000000000000000007184 167.0
PYH2_k127_6114598_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 570.0
PYH2_k127_6114598_1 COG COG3547 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000004496 167.0
PYH2_k127_6125484_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.000000000000000000000000000000000000000000000000000000001517 215.0
PYH2_k127_6125484_1 DoxX K16937 - 1.8.5.2 0.000000000000000000000000000000000000009437 163.0
PYH2_k127_6125484_2 23S rRNA-intervening sequence protein - - - 0.00000000005432 64.0
PYH2_k127_6162264_0 phosphorelay signal transduction system K02481,K07713,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 581.0
PYH2_k127_6162264_1 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 418.0
PYH2_k127_6162264_2 protein histidine kinase activity K02484,K07636 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000003992 247.0
PYH2_k127_6162264_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000001534 241.0
PYH2_k127_6162264_4 3'-5' exonuclease K03684 - 3.1.13.5 0.00000000000000000000000000000000000000000000000000000000000000000003894 246.0
PYH2_k127_6162264_5 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000001652 205.0
PYH2_k127_6162264_6 Peptidase family M54 K06974 - - 0.0000000000000000000000000000000000000008935 154.0
PYH2_k127_6162264_7 glycosyl transferase family 2 - - - 0.000000000000000000002128 103.0
PYH2_k127_6162264_8 Glycine cleavage H-protein - - - 0.00000000000005792 80.0
PYH2_k127_6162264_9 STAS domain - - - 0.00005036 45.0
PYH2_k127_616340_0 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 438.0
PYH2_k127_6172436_0 Major Facilitator Superfamily - - - 0.0000000000000002236 92.0
PYH2_k127_6198162_1 cell division protein - - - 0.00002835 50.0
PYH2_k127_6198290_0 Polysaccharide biosynthesis/export protein K01991 - - 0.00000000000000000000000000006598 126.0
PYH2_k127_6198290_1 CobQ CobB MinD ParA nucleotide binding domain - - - 0.0000003972 62.0
PYH2_k127_6198290_2 Putative beta-barrel porin 2 - - - 0.0003164 53.0
PYH2_k127_6204157_0 cell adhesion involved in biofilm formation K13735,K20276 - - 7.025e-201 669.0
PYH2_k127_6204157_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 314.0
PYH2_k127_6204157_2 transposition K07497 - - 0.00000000000000006976 83.0
PYH2_k127_6204157_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.000000000000001005 82.0
PYH2_k127_6204157_4 PFAM SNARE associated Golgi protein K03975 - - 0.000000000005141 66.0
PYH2_k127_6204157_5 Carboxypeptidase regulatory-like domain - - - 0.00000519 49.0
PYH2_k127_6217442_0 Single-strand binding protein family K03111 - - 0.000000000000000000000000000001188 126.0
PYH2_k127_6217442_1 LVIVD repeat - - - 0.00000000000000003432 96.0
PYH2_k127_6217442_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000837 64.0
PYH2_k127_6217442_3 Iron dependent repressor DNA binding domain protein K03709 - - 0.000003812 51.0
PYH2_k127_6220958_0 Amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000005898 220.0
PYH2_k127_6220958_1 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000002591 124.0
PYH2_k127_6220958_2 Tetratricopeptide repeats - - - 0.00000000000000000007532 93.0
PYH2_k127_6220958_3 Transposase - - - 0.00000000447 64.0
PYH2_k127_6220958_4 PFAM oxidoreductase domain protein - - - 0.0000004377 55.0
PYH2_k127_623476_0 Cytochrome c554 and c-prime - - - 0.0 1016.0
PYH2_k127_623476_1 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 325.0
PYH2_k127_6236782_0 Radical SAM - - - 7.424e-300 930.0
PYH2_k127_6236782_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000001348 207.0
PYH2_k127_6236782_2 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000007952 177.0
PYH2_k127_6252571_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 550.0
PYH2_k127_6262717_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 372.0
PYH2_k127_6262717_1 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004686 301.0
PYH2_k127_6262717_2 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001658 280.0
PYH2_k127_6262717_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000001031 235.0
PYH2_k127_6262717_4 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000007435 216.0
PYH2_k127_6268861_0 Homocysteine S-methyltransferase K00544,K00548 - 2.1.1.13,2.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000535 273.0
PYH2_k127_6268861_1 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000007324 207.0
PYH2_k127_6268861_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000003215 209.0
PYH2_k127_6268861_4 tetratricopeptide repeat - - - 0.0001904 52.0
PYH2_k127_6268861_5 - - - - 0.000952 47.0
PYH2_k127_6298731_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281 - 1.4.4.2 0.0 1369.0
PYH2_k127_6298731_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 503.0
PYH2_k127_6298731_10 exodeoxyribonuclease I activity K01469,K01473 - 3.5.2.14,3.5.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 311.0
PYH2_k127_6298731_11 Protein of unknown function (DUF229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001113 258.0
PYH2_k127_6298731_12 competence protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006617 254.0
PYH2_k127_6298731_13 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000005357 199.0
PYH2_k127_6298731_14 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000000000000000000000003599 180.0
PYH2_k127_6298731_15 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.000000000000000000000000000000000000000000001672 168.0
PYH2_k127_6298731_16 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000001992 162.0
PYH2_k127_6298731_17 PFAM response regulator receiver K02488,K02658 - 2.7.7.65 0.000000000000000000000000000000000000001146 164.0
PYH2_k127_6298731_18 Chemotaxis phosphatase CheX - - - 0.00000000000000003794 87.0
PYH2_k127_6298731_2 Sugar transport protein K05340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 448.0
PYH2_k127_6298731_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 445.0
PYH2_k127_6298731_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 418.0
PYH2_k127_6298731_5 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 392.0
PYH2_k127_6298731_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005265 378.0
PYH2_k127_6298731_7 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 322.0
PYH2_k127_6298731_8 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 319.0
PYH2_k127_6298731_9 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 304.0
PYH2_k127_632123_0 Putative transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 473.0
PYH2_k127_632123_1 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 346.0
PYH2_k127_632123_2 phage integrase domain protein SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 332.0
PYH2_k127_632505_0 NADP-dependent oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001043 254.0
PYH2_k127_632505_1 2-Nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000001105 170.0
PYH2_k127_632505_2 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000001258 84.0
PYH2_k127_632505_3 PFAM AMP-dependent synthetase and ligase K01897,K22319 - 6.1.3.1,6.2.1.3 0.0000002848 56.0
PYH2_k127_6361761_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 1.446e-253 797.0
PYH2_k127_6361761_1 Dehydrogenase K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008045 515.0
PYH2_k127_6361761_2 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 466.0
PYH2_k127_6361761_3 23S rRNA-intervening sequence protein - - - 0.0000000001848 63.0
PYH2_k127_6362379_0 Phosphate acyltransferases K01897 - 6.2.1.3 4.772e-290 913.0
PYH2_k127_6362379_1 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 311.0
PYH2_k127_6362379_3 Transcription termination factor nusG - - - 0.0000000000000000000000000000000000000003291 154.0
PYH2_k127_6362379_4 Membrane protein, TerC K05794 - - 0.000000000000000000007484 94.0
PYH2_k127_6362379_5 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000000001433 85.0
PYH2_k127_6365292_0 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 504.0
PYH2_k127_6365292_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 347.0
PYH2_k127_6365292_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 347.0
PYH2_k127_6375359_0 Peptidase M1, membrane alanine aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 391.0
PYH2_k127_6375359_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002634 287.0
PYH2_k127_6375359_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000000001429 136.0
PYH2_k127_6375359_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000008375 69.0
PYH2_k127_6375359_4 23S rRNA-intervening sequence protein - - - 0.0000004944 52.0
PYH2_k127_6382941_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 306.0
PYH2_k127_6382941_1 PFAM Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000002583 196.0
PYH2_k127_6382941_2 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.0000000000000000000000000000000000402 139.0
PYH2_k127_6382941_3 Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000000354 131.0
PYH2_k127_6382941_4 Peptidase M14, carboxypeptidase A - - - 0.000000003588 59.0
PYH2_k127_6382941_5 Integrase - - - 0.000000008694 59.0
PYH2_k127_6382941_6 Integrase catalytic - - - 0.0002677 46.0
PYH2_k127_6394042_0 - - - - 0.000000000000000000000000000000001476 138.0
PYH2_k127_6394042_1 Transglutaminase-like superfamily - - - 0.000000000000000000000000000001497 134.0
PYH2_k127_6394042_2 Tetratricopeptide repeat - - - 0.000008888 57.0
PYH2_k127_6394042_3 Dehydrogenase K05296 - 1.1.1.51 0.0000351 54.0
PYH2_k127_6404846_0 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 390.0
PYH2_k127_6404846_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 303.0
PYH2_k127_6404846_2 ABC transporter K06861 - - 0.0000000000000000000000000000000000003631 141.0
PYH2_k127_6404846_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000008502 97.0
PYH2_k127_6404846_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000004075 102.0
PYH2_k127_6405399_0 lipoprotein transporter activity K02003,K05685,K09810 - - 0.000000000000000000000000000000000000000000000000001379 192.0
PYH2_k127_6405399_1 efflux transmembrane transporter activity K02004 - - 0.0000000000000000000000000000000000000000000006491 180.0
PYH2_k127_6405399_2 Glycosyl hydrolases family 8 K15531 - 3.2.1.156 0.0003328 44.0
PYH2_k127_6409701_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005432 618.0
PYH2_k127_6409701_1 beta-galactosidase activity - - - 0.0000000000000003111 81.0
PYH2_k127_6409701_2 PFAM Tetratricopeptide - - - 0.0001368 47.0
PYH2_k127_6421527_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 558.0
PYH2_k127_6421527_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 516.0
PYH2_k127_643487_0 PFAM Response regulator receiver domain K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 512.0
PYH2_k127_643487_1 V4R - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001174 270.0
PYH2_k127_643487_2 23S rRNA-intervening sequence protein - - - 0.00000000000000005824 83.0
PYH2_k127_643487_3 radical SAM domain protein - - - 0.0000000004258 72.0
PYH2_k127_6437601_0 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 333.0
PYH2_k127_6437601_1 peptidase activity - - - 0.00000000002077 66.0
PYH2_k127_6437601_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0006068 47.0
PYH2_k127_6452811_0 DNA repair exonuclease K03547 - - 0.0000000000000000000000000000000000000000000000000146 194.0
PYH2_k127_6452811_1 DEAD DEAH box helicase K06877 - - 0.0000000000000000000000000000001804 131.0
PYH2_k127_6452811_2 NlpC/P60 family K21471 - - 0.0000000000000005319 85.0
PYH2_k127_6452811_3 Psort location Cytoplasmic, score 8.87 - - - 0.000000002647 64.0
PYH2_k127_6452811_4 Domain of Unknown Function (DUF350) - - - 0.000003691 51.0
PYH2_k127_6480686_0 PFAM N-acetylneuraminic acid synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004678 295.0
PYH2_k127_6480686_1 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000385 248.0
PYH2_k127_6480686_2 PFAM Nucleotidyl transferase - - - 0.00000000000000000000000000000005729 126.0
PYH2_k127_6486319_0 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007165 383.0
PYH2_k127_6486319_1 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.0000000000000000000000000000000000002762 152.0
PYH2_k127_6533437_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.864e-204 664.0
PYH2_k127_6533437_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 458.0
PYH2_k127_6533437_10 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.000000000001221 67.0
PYH2_k127_6533437_11 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000002863 68.0
PYH2_k127_6533437_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001067 265.0
PYH2_k127_6533437_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000002024 226.0
PYH2_k127_6533437_4 adenylate kinase activity K00939 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004017,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006412,GO:0006518,GO:0006629,GO:0006644,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0010467,GO:0015949,GO:0015950,GO:0015951,GO:0016070,GO:0016208,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019205,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0046872,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000001484 210.0
PYH2_k127_6533437_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000001683 179.0
PYH2_k127_6533437_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001831 168.0
PYH2_k127_6533437_7 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000007052 160.0
PYH2_k127_6533437_8 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000001118 158.0
PYH2_k127_6533437_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000003189 134.0
PYH2_k127_6553859_0 Redoxin - - - 0.00000000000135 75.0
PYH2_k127_6553859_1 PFAM Uncharacterised protein family (UPF0104) K07027 - - 0.000000000448 71.0
PYH2_k127_6555480_0 PFAM peptidase K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 334.0
PYH2_k127_6555480_1 Methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 295.0
PYH2_k127_6555480_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000387 274.0
PYH2_k127_6555480_3 Glyco_18 K01448,K07260,K20276 - 3.4.17.14,3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000006642 242.0
PYH2_k127_6555480_4 cytochrome oxidase assembly K02259 - - 0.00000000000000000000000000000000000000000000000000004444 199.0
PYH2_k127_6555480_5 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000007503 213.0
PYH2_k127_6555480_6 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000001981 184.0
PYH2_k127_6555480_7 Bacterial membrane protein, YfhO - - - 0.00000000004537 77.0
PYH2_k127_6555480_8 Tetratricopeptide TPR_2 repeat protein - - - 0.000000003342 70.0
PYH2_k127_6563730_0 Two component transcriptional regulator, LuxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006562 288.0
PYH2_k127_6563730_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003059 244.0
PYH2_k127_6563730_3 finger protein K16276 GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0032446,GO:0036211,GO:0043161,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0051603,GO:0061630,GO:0061659,GO:0070647,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000002572 81.0
PYH2_k127_6563730_4 - - - - 0.00001893 50.0
PYH2_k127_6569900_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 542.0
PYH2_k127_6569900_1 Ribosomal protein L11 methyltransferase (PrmA) K02169 - 2.1.1.197 0.000000000000000003213 89.0
PYH2_k127_6569900_2 Ami_2 - - - 0.00000000000006324 85.0
PYH2_k127_6569900_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.0000000000003351 83.0
PYH2_k127_6574272_0 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 481.0
PYH2_k127_6574272_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 393.0
PYH2_k127_6574272_2 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 299.0
PYH2_k127_6575552_0 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 587.0
PYH2_k127_6575552_1 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000005591 104.0
PYH2_k127_6575552_2 Integrase - - - 0.00000000000000000000002559 108.0
PYH2_k127_6575552_3 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000000001377 83.0
PYH2_k127_6575552_4 cAMP biosynthetic process K08884,K12132 - 2.7.11.1 0.00000000000004565 78.0
PYH2_k127_6583087_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 4.715e-204 653.0
PYH2_k127_6583087_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 454.0
PYH2_k127_6583087_2 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002938 287.0
PYH2_k127_6587052_0 Beta-L-arabinofuranosidase, GH127 K02169 - 2.1.1.197 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 352.0
PYH2_k127_6587621_0 Belongs to the 'phage' integrase family - - - 0.00000000000003924 84.0
PYH2_k127_6587621_1 AAA domain K07133 - - 0.000000002025 60.0
PYH2_k127_6587621_2 Transcriptional regulator - - - 0.0004167 46.0
PYH2_k127_6587621_3 Amino acid adenylation domain - - - 0.0004861 48.0
PYH2_k127_6590423_0 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000008866 174.0
PYH2_k127_6590423_1 PFAM Metal-dependent hydrolase HDOD - - - 0.00000000000000000000000000000000004308 145.0
PYH2_k127_6590423_2 Regulatory protein, FmdB family - - - 0.0000000000000000000009324 97.0
PYH2_k127_6590423_3 - - - - 0.0000001687 59.0
PYH2_k127_6590423_4 Diguanylate cyclase - - - 0.000633 51.0
PYH2_k127_6597405_0 Amino acid permease K03294,K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 336.0
PYH2_k127_6597405_1 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000001358 216.0
PYH2_k127_6597832_0 metallocarboxypeptidase activity K14054 - - 2.152e-199 634.0
PYH2_k127_6597832_1 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 523.0
PYH2_k127_6597832_10 peptide deformylase activity K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000002635 203.0
PYH2_k127_6597832_11 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000001935 165.0
PYH2_k127_6597832_12 HIT domain K02503 - - 0.00000000000000000000000000000000000001352 151.0
PYH2_k127_6597832_13 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000003704 150.0
PYH2_k127_6597832_14 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000005561 118.0
PYH2_k127_6597832_15 Xylose isomerase-like TIM barrel K18910 - 5.1.3.30,5.1.3.31 0.0000001398 62.0
PYH2_k127_6597832_2 radical SAM domain protein K15045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 494.0
PYH2_k127_6597832_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 495.0
PYH2_k127_6597832_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 469.0
PYH2_k127_6597832_5 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 409.0
PYH2_k127_6597832_6 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 356.0
PYH2_k127_6597832_7 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 346.0
PYH2_k127_6597832_8 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001167 265.0
PYH2_k127_6597832_9 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000002105 217.0
PYH2_k127_6602832_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 592.0
PYH2_k127_6602832_1 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002765 249.0
PYH2_k127_6602832_2 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000001792 220.0
PYH2_k127_6602832_3 Endonuclease containing a URI domain K07461 - - 0.00000000005845 66.0
PYH2_k127_6602832_4 PFAM IstB domain protein ATP-binding protein - - - 0.00002662 48.0
PYH2_k127_6615184_0 xylulokinase activity K00854 - 2.7.1.17 1.026e-207 658.0
PYH2_k127_6615184_1 carboxylic acid catabolic process K01684 - 4.2.1.6 3.622e-203 640.0
PYH2_k127_6615184_2 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 348.0
PYH2_k127_6615184_3 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 330.0
PYH2_k127_6615184_4 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001513 344.0
PYH2_k127_6615184_5 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000234 87.0
PYH2_k127_6619422_0 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K18930 - - 2.4e-271 850.0
PYH2_k127_6625254_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1111.0
PYH2_k127_6625254_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008158 580.0
PYH2_k127_6625254_10 Outer membrane protein (OmpH-like) K06142 - - 0.000000000000007354 83.0
PYH2_k127_6625254_11 CDP-alcohol phosphatidyltransferase K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000004917 68.0
PYH2_k127_6625254_2 TIGRFAM outer membrane protein assembly complex, YaeT protein K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 530.0
PYH2_k127_6625254_3 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 361.0
PYH2_k127_6625254_4 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000547 351.0
PYH2_k127_6625254_5 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007707 271.0
PYH2_k127_6625254_6 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000007999 232.0
PYH2_k127_6625254_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000009087 199.0
PYH2_k127_6625254_8 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000004152 179.0
PYH2_k127_6625254_9 NusB family K03625 - - 0.000000000000000000000000000000000002339 141.0
PYH2_k127_6642443_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 1.236e-214 684.0
PYH2_k127_6642443_1 TIGRFAM methylmalonyl-CoA mutase, large subunit K01847,K01848 - 5.4.99.2 4.325e-211 667.0
PYH2_k127_6642443_10 PFAM Single-stranded nucleic acid binding R3H K06346 - - 0.00000000000000000005873 95.0
PYH2_k127_6642443_11 Polymer-forming cytoskeletal - - - 0.00000000000000000008651 94.0
PYH2_k127_6642443_12 - - - - 0.000000000000001207 79.0
PYH2_k127_6642443_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000001601 78.0
PYH2_k127_6642443_14 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.000000000000187 81.0
PYH2_k127_6642443_15 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000001033 71.0
PYH2_k127_6642443_16 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000001001 66.0
PYH2_k127_6642443_17 Yip1 domain - - - 0.000004003 50.0
PYH2_k127_6642443_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002648 375.0
PYH2_k127_6642443_3 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 350.0
PYH2_k127_6642443_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 326.0
PYH2_k127_6642443_5 Cellulose biosynthesis protein BcsQ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 303.0
PYH2_k127_6642443_6 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007443 281.0
PYH2_k127_6642443_7 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 GO:0002790,GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006457,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022607,GO:0031224,GO:0031226,GO:0032940,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0043933,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046903,GO:0051179,GO:0051205,GO:0051234,GO:0051259,GO:0051260,GO:0051641,GO:0061024,GO:0065003,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.0000000000000000000000000000000000000000000000000000000000000000000000002993 268.0
PYH2_k127_6642443_8 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000009097 228.0
PYH2_k127_6642443_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000001303 102.0
PYH2_k127_6643041_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 545.0
PYH2_k127_6643041_1 PFAM amidohydrolase K01464 - 3.5.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 434.0
PYH2_k127_6643041_2 Cytidine monophosphokinase K00876 - 2.7.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000003496 255.0
PYH2_k127_6643041_3 solute binding protein K02035 - - 0.00000009319 65.0
PYH2_k127_6645218_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000002133 190.0
PYH2_k127_6645218_2 Plasmid stabilization system K19093 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000001149 156.0
PYH2_k127_6645218_3 Putative addiction module component - - - 0.0000000000000000000000000000000000429 134.0
PYH2_k127_6645218_4 peptidyl-tyrosine sulfation - - - 0.0000000005667 62.0
PYH2_k127_6651709_0 Protein tyrosine kinase - - - 0.000000009872 66.0
PYH2_k127_6655231_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.872e-298 931.0
PYH2_k127_6655231_1 Domain of unknown function (DUF5107) - - - 5.919e-246 793.0
PYH2_k127_6655231_10 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000005827 146.0
PYH2_k127_6655231_11 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000003104 114.0
PYH2_k127_6655231_2 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 9.194e-246 779.0
PYH2_k127_6655231_3 acyl-CoA dehydrogenase activity K00252 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.3.8.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007211 533.0
PYH2_k127_6655231_4 Glycosyl hydrolase family 57 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009983 541.0
PYH2_k127_6655231_5 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 438.0
PYH2_k127_6655231_6 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 425.0
PYH2_k127_6655231_7 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 347.0
PYH2_k127_6655231_8 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 336.0
PYH2_k127_6655231_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002453 274.0
PYH2_k127_6663304_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 385.0
PYH2_k127_6663304_1 Belongs to the fatty acid desaturase type 1 family K20416 GO:0000038,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0012505,GO:0016020,GO:0016053,GO:0016491,GO:0019752,GO:0031984,GO:0032787,GO:0033559,GO:0042175,GO:0042761,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:0072330,GO:0098827,GO:1901576 1.14.19.42 0.000000000000000000000000000000000000000008697 164.0
PYH2_k127_6664446_0 Heat shock 70 kDa protein K04043 - - 8.053e-308 954.0
PYH2_k127_6664446_1 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 4.974e-218 687.0
PYH2_k127_6664446_10 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000008392 148.0
PYH2_k127_6664446_11 PFAM regulatory protein, MerR K13640 - - 0.000000000000000000000000000000000005087 140.0
PYH2_k127_6664446_12 OmpA family K03640 - - 0.000000000000001526 91.0
PYH2_k127_6664446_13 - - GO:0003674,GO:0005488,GO:0005509,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0007275,GO:0008150,GO:0009555,GO:0009653,GO:0009987,GO:0010208,GO:0010584,GO:0010927,GO:0012505,GO:0016020,GO:0016043,GO:0022607,GO:0030198,GO:0032501,GO:0032502,GO:0032989,GO:0043062,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0045229,GO:0046872,GO:0048229,GO:0048646,GO:0048856,GO:0048869,GO:0071840,GO:0085029 - 0.0000000000002249 84.0
PYH2_k127_6664446_14 - - - - 0.000001178 56.0
PYH2_k127_6664446_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.379e-210 664.0
PYH2_k127_6664446_3 Glutamine synthetase, beta-Grasp domain K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 539.0
PYH2_k127_6664446_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003466 407.0
PYH2_k127_6664446_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 385.0
PYH2_k127_6664446_6 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 367.0
PYH2_k127_6664446_7 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 340.0
PYH2_k127_6664446_8 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002344 266.0
PYH2_k127_6664446_9 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001245 256.0
PYH2_k127_6665609_0 cephalosporin-C deacetylase activity K01061 - 3.1.1.45 3.744e-204 664.0
PYH2_k127_6665609_1 alpha-L-rhamnosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 589.0
PYH2_k127_6665609_2 D-aminopeptidase K16203 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000918 377.0
PYH2_k127_6665609_3 NHL repeat-containing protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009416,GO:0009507,GO:0009532,GO:0009534,GO:0009536,GO:0009570,GO:0009579,GO:0009628,GO:0010196,GO:0016020,GO:0031976,GO:0031984,GO:0034357,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0050896,GO:1990066 - 0.0000000000000000000000000000000000000000000000000000000203 204.0
PYH2_k127_6674545_0 PFAM peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 541.0
PYH2_k127_6674545_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 376.0
PYH2_k127_6674545_2 23S rRNA-intervening sequence protein - - - 0.0000001897 53.0
PYH2_k127_6674545_3 peptidyl-tyrosine sulfation - - - 0.0001006 54.0
PYH2_k127_6680841_0 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006129 516.0
PYH2_k127_6680841_1 PFAM Prenyltransferase squalene oxidase K06045 - 4.2.1.129,5.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007128 479.0
PYH2_k127_6680841_2 COG0402 Cytosine deaminase and related metal-dependent K20810 - 3.5.4.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 304.0
PYH2_k127_6680841_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.00008055 46.0
PYH2_k127_6688042_0 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000003787 220.0
PYH2_k127_6688042_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000008912 135.0
PYH2_k127_6688042_2 polysaccharide catabolic process K01179 - 3.2.1.4 0.000000002235 67.0
PYH2_k127_6694052_0 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 346.0
PYH2_k127_6694052_1 PFAM Transposase IS66 family K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 316.0
PYH2_k127_6694052_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.00000001513 61.0
PYH2_k127_6701182_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family K13687 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 421.0
PYH2_k127_6701182_1 Bacterial membrane protein, YfhO - - - 0.000000000000000000000000000000000000000000001116 189.0
PYH2_k127_6706173_0 alpha beta - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003476 343.0
PYH2_k127_6706951_0 membrane protein, TerC K05794 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 345.0
PYH2_k127_6706951_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 303.0
PYH2_k127_6706951_2 HNH endonuclease K07451 - - 0.000000000000000000000664 101.0
PYH2_k127_6726739_0 4Fe-4S single cluster domain K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 368.0
PYH2_k127_6726739_1 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006959 265.0
PYH2_k127_6726739_2 TIGRFAM bacillithiol system protein YtxJ - - - 0.0000000000000000000004723 104.0
PYH2_k127_6726739_3 23S rRNA-intervening sequence protein - - - 0.00000000000000000006252 91.0
PYH2_k127_6726739_4 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000003805 95.0
PYH2_k127_6726739_5 Catalyzes the dehydration of D-mannonate - - - 0.0000000000002546 72.0
PYH2_k127_6726739_6 - - - - 0.00000000191 69.0
PYH2_k127_6726739_7 CHAD - - - 0.0000002212 63.0
PYH2_k127_6732898_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 2.086e-250 781.0
PYH2_k127_6732898_1 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 601.0
PYH2_k127_6732898_10 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.00000000000000000000005692 109.0
PYH2_k127_6732898_11 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000000000000000001784 102.0
PYH2_k127_6732898_12 Biotin-requiring enzyme - - - 0.000000000000000000005206 99.0
PYH2_k127_6732898_13 Integrase - - - 0.00000000000003759 74.0
PYH2_k127_6732898_14 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000002976 66.0
PYH2_k127_6732898_15 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.000000000204 72.0
PYH2_k127_6732898_16 selenium-dependent hydroxylase accessory protein YqeC - - - 0.000000001425 68.0
PYH2_k127_6732898_17 Protein of unknown function (DUF1838) - - - 0.000000007473 65.0
PYH2_k127_6732898_18 PFAM NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 0.0000000813 59.0
PYH2_k127_6732898_19 Major Facilitator Superfamily - - - 0.0002299 47.0
PYH2_k127_6732898_2 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 572.0
PYH2_k127_6732898_20 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.0008057 53.0
PYH2_k127_6732898_3 Right handed beta helix region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 466.0
PYH2_k127_6732898_4 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 451.0
PYH2_k127_6732898_5 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 404.0
PYH2_k127_6732898_6 TLC ATP/ADP transporter K03301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001379 273.0
PYH2_k127_6732898_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000000005889 240.0
PYH2_k127_6732898_8 UTRA K03710 - - 0.000000000000000000000000000000000000002513 157.0
PYH2_k127_6732898_9 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141 - 2.7.7.76 0.000000000000000000000000002863 121.0
PYH2_k127_6735725_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.173e-206 649.0
PYH2_k127_6735725_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 585.0
PYH2_k127_6735725_2 ATPase associated with various cellular K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 457.0
PYH2_k127_6735725_3 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003964 360.0
PYH2_k127_6735725_4 von Willebrand factor (vWF) type A domain K07114,K12511 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 343.0
PYH2_k127_6735725_5 von Willebrand factor (vWF) type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006599 284.0
PYH2_k127_6735725_6 Oxygen tolerance - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001303 268.0
PYH2_k127_6735725_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000009344 125.0
PYH2_k127_6735725_8 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000007224 120.0
PYH2_k127_6735725_9 Psort location CytoplasmicMembrane, score - - - 0.000000000000000007031 96.0
PYH2_k127_6737418_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 4.17e-311 976.0
PYH2_k127_6737418_1 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 379.0
PYH2_k127_6737418_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 338.0
PYH2_k127_6737418_3 Crp-like helix-turn-helix domain K10914 - - 0.000000000000000000000000000000000000000000000000000007858 196.0
PYH2_k127_6737418_4 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000455 167.0
PYH2_k127_6737418_5 - - - - 0.00000000000000005177 93.0
PYH2_k127_6737418_6 response regulator - - - 0.0007031 47.0
PYH2_k127_6752692_0 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002256 381.0
PYH2_k127_6755109_0 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002135 279.0
PYH2_k127_6756461_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 1.905e-262 822.0
PYH2_k127_6756461_1 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182 - 4.1.1.98 1.836e-255 796.0
PYH2_k127_6756461_2 pyruvate phosphate dikinase, PEP K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 294.0
PYH2_k127_6756461_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008203 250.0
PYH2_k127_6756461_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.0000000000000000000000000000000000000000000000000000000006877 215.0
PYH2_k127_6756461_5 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000156 161.0
PYH2_k127_6756461_6 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000002273 121.0
PYH2_k127_6757269_0 Protein kinase domain K12132 - 2.7.11.1 1.599e-231 751.0
PYH2_k127_6757269_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.56e-220 714.0
PYH2_k127_6757269_10 Domain of unknown function (DUF4340) - - - 0.000000000000000000000000000000000002744 155.0
PYH2_k127_6757269_11 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000002482 108.0
PYH2_k127_6757269_12 lipopolysaccharide metabolic process K08309,K19804 - - 0.000000000000000001653 99.0
PYH2_k127_6757269_13 Protein of unknown function (DUF503) K09764 - - 0.0000000000000001681 83.0
PYH2_k127_6757269_14 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.0000000000000004418 81.0
PYH2_k127_6757269_15 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000001443 63.0
PYH2_k127_6757269_16 O-antigen ligase like membrane protein - - - 0.00006981 52.0
PYH2_k127_6757269_2 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 450.0
PYH2_k127_6757269_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 373.0
PYH2_k127_6757269_4 ABC-type uncharacterized transport system K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 361.0
PYH2_k127_6757269_5 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 337.0
PYH2_k127_6757269_6 PFAM ROK family protein K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007284 332.0
PYH2_k127_6757269_7 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000004791 225.0
PYH2_k127_6757269_8 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000001368 220.0
PYH2_k127_6757269_9 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000003887 145.0
PYH2_k127_6765673_0 Carboxypeptidase regulatory-like domain - - - 1.336e-255 815.0
PYH2_k127_6765673_1 Aldo/keto reductase family - - - 0.00000000000002799 73.0
PYH2_k127_6781377_0 tryptophan synthase activity K01696,K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 597.0
PYH2_k127_6781377_1 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000005151 189.0
PYH2_k127_6787431_0 TonB-dependent Receptor Plug Domain - - - 0.0 1476.0
PYH2_k127_6787431_1 Oligopeptidase F K08602 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 584.0
PYH2_k127_6787431_10 transporter - - - 0.00000000000000000000000000000000000000000000000000005995 203.0
PYH2_k127_6787431_11 dTDP-4-dehydrorhamnose reductase K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000005724 177.0
PYH2_k127_6787431_12 4Fe-4S dicluster domain K05796 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0044424,GO:0044464,GO:0055114 - 0.0000000000000000000000000002905 120.0
PYH2_k127_6787431_13 PIN domain - - - 0.0000000000000000000000001022 110.0
PYH2_k127_6787431_14 ribonuclease activity - - - 0.00000000000000000000001696 105.0
PYH2_k127_6787431_15 Protein of unknown function (DUF4038) - - - 0.0000000000000000000001823 96.0
PYH2_k127_6787431_16 4Fe-4S dicluster domain - - - 0.0000000000000000000003147 104.0
PYH2_k127_6787431_17 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000001091 102.0
PYH2_k127_6787431_18 PFAM PilT protein domain protein - - - 0.0000000000000004897 83.0
PYH2_k127_6787431_19 - - - - 0.0000001167 64.0
PYH2_k127_6787431_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 518.0
PYH2_k127_6787431_20 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000001335 53.0
PYH2_k127_6787431_21 SpoVT / AbrB like domain - - - 0.0001484 47.0
PYH2_k127_6787431_22 Integrin alpha (beta-propellor repeats). - - - 0.000179 51.0
PYH2_k127_6787431_3 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 490.0
PYH2_k127_6787431_4 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 450.0
PYH2_k127_6787431_5 Amino acid permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 444.0
PYH2_k127_6787431_6 PFAM CBS domain containing protein K03281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006176 400.0
PYH2_k127_6787431_7 oxidoreductase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002839 339.0
PYH2_k127_6787431_8 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002509 290.0
PYH2_k127_6787431_9 (ABC) transporter K02471,K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006551 270.0
PYH2_k127_6789987_0 Belongs to the glycosyl hydrolase 67 family - - - 3.836e-297 932.0
PYH2_k127_6789987_1 Neu5Ac) to form pyruvate and N-acetylmannosamine (ManNAc) via a Schiff base intermediate K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 368.0
PYH2_k127_6789987_2 Lactoylglutathione lyase K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000003993 201.0
PYH2_k127_6789987_3 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000007367 175.0
PYH2_k127_6789987_4 ABC-2 type transporter K09690 - - 0.0000000000000000000000000001046 120.0
PYH2_k127_6789987_5 radical SAM domain protein - - - 0.0000000001175 72.0
PYH2_k127_6796180_0 Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 436.0
PYH2_k127_6796180_1 4 iron, 4 sulfur cluster binding K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 297.0
PYH2_k127_6796180_2 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000006581 122.0
PYH2_k127_6796180_3 Lipid A 3-O-deacylase (PagL) - - - 0.0000000000000004314 86.0
PYH2_k127_6797537_0 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00009355 52.0
PYH2_k127_6797537_1 Protein of unknown function (DUF2283) - - - 0.0004289 50.0
PYH2_k127_6808036_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0016625,GO:0016903,GO:0043873,GO:0050896,GO:0055114 1.2.7.1 0.0 1692.0
PYH2_k127_6808036_1 COG0464 ATPases of the AAA class - - - 2.091e-194 622.0
PYH2_k127_6808036_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 508.0
PYH2_k127_6808036_3 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 422.0
PYH2_k127_6808036_4 - - - - 0.0000000000000000000000000000000000000000000000000000002063 198.0
PYH2_k127_6808036_5 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000002004 93.0
PYH2_k127_6808036_6 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000005288 82.0
PYH2_k127_682100_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009178 339.0
PYH2_k127_6824063_0 Acetyl-coenzyme A synthetase N-terminus K01895 - 6.2.1.1 0.0 1065.0
PYH2_k127_6824063_1 Succinyl-CoA ligase like flavodoxin domain K09181 - - 3.927e-290 912.0
PYH2_k127_6824063_10 PFAM PfkB K00874 - 2.7.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002068 451.0
PYH2_k127_6824063_11 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 347.0
PYH2_k127_6824063_13 Amidinotransferase K01482 - 3.5.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 290.0
PYH2_k127_6824063_14 CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001338 264.0
PYH2_k127_6824063_15 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004601 264.0
PYH2_k127_6824063_16 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000154 261.0
PYH2_k127_6824063_17 PFAM Uncharacterised BCR, COG1649 K01448 - 3.5.1.28 0.000000000000000000000000000000000004958 147.0
PYH2_k127_6824063_18 - - - - 0.000000000000000000000000009699 113.0
PYH2_k127_6824063_19 acyl carrier protein K02078 - - 0.00000000000000000214 87.0
PYH2_k127_6824063_2 Glycosyl hydrolase family 65, N-terminal domain K15923 - 3.2.1.51 2.426e-234 752.0
PYH2_k127_6824063_20 Tetratricopeptide repeat - - - 0.000000000000002975 91.0
PYH2_k127_6824063_21 peptidyl-tyrosine sulfation - - - 0.000000000003703 79.0
PYH2_k127_6824063_3 PFAM Mandelate racemase muconate lactonizing enzyme, N-terminal domain protein K01684 - 4.2.1.6 1.085e-195 618.0
PYH2_k127_6824063_4 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 582.0
PYH2_k127_6824063_5 transmembrane transporter activity K03535,K08194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005958 569.0
PYH2_k127_6824063_6 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 531.0
PYH2_k127_6824063_7 Belongs to the beta-ketoacyl-ACP synthases family K14660 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000224 513.0
PYH2_k127_6824063_8 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 479.0
PYH2_k127_6824063_9 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 469.0
PYH2_k127_6824321_0 response regulator - - - 2.1e-204 644.0
PYH2_k127_6824321_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 518.0
PYH2_k127_6824321_2 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K02564 - 3.5.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 291.0
PYH2_k127_6824321_3 Amidohydrolase family K01443 - 3.5.1.25 0.0000000000000000000000000000000000000000000000000000000000008436 221.0
PYH2_k127_6824321_4 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000000000000000000007592 201.0
PYH2_k127_6843502_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1373.0
PYH2_k127_6843502_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 2.288e-232 734.0
PYH2_k127_6843502_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000002495 150.0
PYH2_k127_6843502_11 LysM domain K01449,K19223 - 3.5.1.28 0.0000000000000000000000000000000005218 144.0
PYH2_k127_6843502_12 2 iron, 2 sulfur cluster binding - - - 0.00000000000000000000000000000000074 136.0
PYH2_k127_6843502_13 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000216 133.0
PYH2_k127_6843502_14 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000000000000000000002151 128.0
PYH2_k127_6843502_15 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.00000000000000000000000004241 121.0
PYH2_k127_6843502_16 PFAM peptidase M52 hydrogen uptake protein K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000000000000000005853 111.0
PYH2_k127_6843502_17 Cytochrome c K00425 - 1.10.3.14 0.000000000000000000002913 102.0
PYH2_k127_6843502_19 - - - - 0.0000272 47.0
PYH2_k127_6843502_2 Alpha-L-arabinofuranosidase C-terminus K01209 - 3.2.1.55 3.429e-222 699.0
PYH2_k127_6843502_20 chaperone-mediated protein complex assembly - - - 0.00005705 54.0
PYH2_k127_6843502_21 Oxidoreductase domain protein - - - 0.0008077 46.0
PYH2_k127_6843502_3 PFAM Cytochrome b b6 domain - - - 1.611e-200 638.0
PYH2_k127_6843502_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 536.0
PYH2_k127_6843502_5 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 519.0
PYH2_k127_6843502_6 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 420.0
PYH2_k127_6843502_7 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 334.0
PYH2_k127_6843502_8 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005468 281.0
PYH2_k127_6843502_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000001221 233.0
PYH2_k127_68517_0 PFAM Transposase IS116 IS110 IS902 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 382.0
PYH2_k127_6905869_0 Alpha-L-fucosidase K01206 - 3.2.1.51 1.856e-230 724.0
PYH2_k127_6905869_1 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 444.0
PYH2_k127_6905869_10 HD domain - - - 0.000000000000000000000000000000000000000001059 169.0
PYH2_k127_6905869_11 Transcriptional regulator K13641 - - 0.000000000000000000000000000000000000000003035 166.0
PYH2_k127_6905869_12 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.000000000000000000000000000000000002644 139.0
PYH2_k127_6905869_13 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000009644 144.0
PYH2_k127_6905869_2 transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 458.0
PYH2_k127_6905869_3 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 455.0
PYH2_k127_6905869_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 439.0
PYH2_k127_6905869_5 isomerase K02082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 361.0
PYH2_k127_6905869_6 sodium bile acid transporter family protein K03453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 321.0
PYH2_k127_6905869_7 Domain of unknown function (DUF4861) K01051 - 3.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001371 286.0
PYH2_k127_6905869_8 Aldolase/RraA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002428 247.0
PYH2_k127_6905869_9 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000007842 180.0
PYH2_k127_6918711_0 domain, Protein - - - 0.0000000000000000000000000001997 129.0
PYH2_k127_6918711_1 protein kinase activity K08884 - 2.7.11.1 0.0000002632 52.0
PYH2_k127_6918711_2 Integrase - - - 0.00008544 47.0
PYH2_k127_6927388_0 amine dehydrogenase activity - - - 1.69e-271 863.0
PYH2_k127_6927388_1 Belongs to the Pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 372.0
PYH2_k127_6927388_2 transmembrane transporter activity K02445,K07783 - - 0.000000000000000000000000000000000000000000000000000008238 203.0
PYH2_k127_6927388_3 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000001822 136.0
PYH2_k127_6927602_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 458.0
PYH2_k127_6927602_1 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003983 424.0
PYH2_k127_6927602_2 Domain of unknown function (DUF4143) - - - 0.00000000000000000000001685 104.0
PYH2_k127_6927602_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000001513 59.0
PYH2_k127_6928013_0 LssY C-terminus - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 625.0
PYH2_k127_6928013_1 NIPSNAP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001067 259.0
PYH2_k127_6928013_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000002285 264.0
PYH2_k127_6928013_3 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000004778 214.0
PYH2_k127_6944703_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 615.0
PYH2_k127_6952175_0 growth of symbiont in host cell K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004947 586.0
PYH2_k127_6952175_1 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 555.0
PYH2_k127_6952175_10 Type IV VI secretion system K11892 - - 0.000000000000000000000000000000000000000002288 164.0
PYH2_k127_6952175_11 Serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000003411 146.0
PYH2_k127_6952175_12 Type VI secretion K11906 - - 0.0000000000000000006842 92.0
PYH2_k127_6952175_13 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000006889 91.0
PYH2_k127_6952175_14 PFAM Forkhead-associated protein - - - 0.000000000001583 77.0
PYH2_k127_6952175_15 YacP-like NYN domain K06962 - - 0.0000000004355 67.0
PYH2_k127_6952175_16 Protein tyrosine kinase - - - 0.00000004717 66.0
PYH2_k127_6952175_2 cystathionine gamma-synthase activity K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 510.0
PYH2_k127_6952175_3 ImcF-related N-terminal domain K11891 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 459.0
PYH2_k127_6952175_4 type VI secretion protein, VC_A0114 family K11893 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 355.0
PYH2_k127_6952175_5 PFAM Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001634 292.0
PYH2_k127_6952175_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000009005 227.0
PYH2_k127_6952175_7 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.000000000000000000000000000000000000000000000000000000000000006594 228.0
PYH2_k127_6952175_8 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000001737 238.0
PYH2_k127_6952175_9 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000003746 194.0
PYH2_k127_6972518_0 efflux transmembrane transporter activity - - - 1.475e-280 885.0
PYH2_k127_6972518_1 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 588.0
PYH2_k127_6972518_2 Glycosyl-hydrolase 97 N-terminal K01187 - 3.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 553.0
PYH2_k127_6972518_3 BNR repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006117 518.0
PYH2_k127_6972518_4 PFAM oxidoreductase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005024 482.0
PYH2_k127_6972518_5 protein domain associated with - - - 0.00000000000000003095 84.0
PYH2_k127_697399_0 lipolytic protein G-D-S-L family - - - 1.096e-252 792.0
PYH2_k127_697399_1 Alpha-L-arabinofuranosidase K01209 - 3.2.1.55 2.197e-230 723.0
PYH2_k127_697399_10 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000001359 85.0
PYH2_k127_697399_11 oxidation-reduction process K09022 - 3.5.99.10 0.000000000008743 77.0
PYH2_k127_697399_12 Cys/Met metabolism PLP-dependent enzyme K01042 - 2.9.1.1 0.0000000003016 63.0
PYH2_k127_697399_2 Cys/Met metabolism PLP-dependent enzyme K01042 - 2.9.1.1 4.872e-222 702.0
PYH2_k127_697399_3 Peptidase family M28 - - - 4.765e-198 638.0
PYH2_k127_697399_4 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 331.0
PYH2_k127_697399_5 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 312.0
PYH2_k127_697399_6 Aldolase/RraA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002562 275.0
PYH2_k127_697399_7 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001062 234.0
PYH2_k127_697399_8 Cys/Met metabolism PLP-dependent enzyme K01042 - 2.9.1.1 0.00000000000000000000001502 102.0
PYH2_k127_697399_9 endoribonuclease L-PSP - - - 0.00000000000000000002229 104.0
PYH2_k127_6987883_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009349 613.0
PYH2_k127_6987883_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000009311 117.0
PYH2_k127_7008077_0 Penicillin amidase K01434 - 3.5.1.11 0.0 1148.0
PYH2_k127_7008077_1 GntP family permease K03299 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 363.0
PYH2_k127_7008077_2 polysaccharide catabolic process K01179 - 3.2.1.4 0.0000000000000000000002161 113.0
PYH2_k127_7008077_3 von Willebrand factor (vWF) type A domain K07114 - - 0.00000006405 61.0
PYH2_k127_7008077_4 - - - - 0.00000007591 57.0
PYH2_k127_7009666_0 PFAM amidohydrolase - - - 6.857e-227 717.0
PYH2_k127_7009666_1 Belongs to the mandelate racemase muconate lactonizing enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 606.0
PYH2_k127_7009666_10 PFAM Tetratricopeptide repeat - - - 0.00009224 54.0
PYH2_k127_7009666_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 594.0
PYH2_k127_7009666_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 469.0
PYH2_k127_7009666_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 361.0
PYH2_k127_7009666_5 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004674 340.0
PYH2_k127_7009666_6 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000527 254.0
PYH2_k127_7009666_7 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000001699 237.0
PYH2_k127_7009666_8 and related - - - 0.00000000000000001308 85.0
PYH2_k127_7009666_9 - - - - 0.0000005975 61.0
PYH2_k127_7010008_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 301.0
PYH2_k127_7010008_1 PFAM MULE transposase, conserved domain - - - 0.000001718 61.0
PYH2_k127_7028309_1 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000001955 107.0
PYH2_k127_7038360_0 Domain of unknown function (DUF4160) - - - 0.00000000000000000000000000000000000001292 145.0
PYH2_k127_7038360_1 Protein of unknown function (DUF2442) - - - 0.0000000000000000000000000002356 116.0
PYH2_k127_7038360_2 Putative transposase - - - 0.000000000000004712 79.0
PYH2_k127_7038360_3 COG3119 Arylsulfatase A - - - 0.0000000000000959 74.0
PYH2_k127_7038563_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 500.0
PYH2_k127_7038563_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 409.0
PYH2_k127_7038563_10 ISSoEn1, terminal inverted repeat - - - 0.000000001551 61.0
PYH2_k127_7038563_11 TonB-dependent Receptor Plug Domain - - - 0.0000007924 55.0
PYH2_k127_7038563_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 318.0
PYH2_k127_7038563_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008597 283.0
PYH2_k127_7038563_4 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000003256 184.0
PYH2_k127_7038563_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000002126 173.0
PYH2_k127_7038563_6 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000111 170.0
PYH2_k127_7038563_7 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001365 157.0
PYH2_k127_7038563_8 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000008015 106.0
PYH2_k127_7038563_9 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000002687 104.0
PYH2_k127_7040315_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 4.258e-259 812.0
PYH2_k127_7040315_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 477.0
PYH2_k127_7049261_0 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 2.619e-305 947.0
PYH2_k127_7051622_0 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 6.271e-312 964.0
PYH2_k127_7051622_1 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 528.0
PYH2_k127_7051622_10 oxidoreductase activity K12511 - - 0.00000000000000000000000009536 119.0
PYH2_k127_7051622_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000006911 108.0
PYH2_k127_7051622_12 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.000000000000000000006562 101.0
PYH2_k127_7051622_13 Putative phosphatase (DUF442) - - - 0.00000000000000001167 90.0
PYH2_k127_7051622_14 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0001603 46.0
PYH2_k127_7051622_15 Bacterial antitoxin of type II TA system, VapB - - - 0.0002559 46.0
PYH2_k127_7051622_2 Transcriptional regulator, DeoR K02081 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004071 326.0
PYH2_k127_7051622_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 306.0
PYH2_k127_7051622_4 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004349 289.0
PYH2_k127_7051622_5 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001125 276.0
PYH2_k127_7051622_6 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005829,GO:0006082,GO:0006090,GO:0006518,GO:0006575,GO:0006749,GO:0006750,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019184,GO:0019752,GO:0031974,GO:0032787,GO:0034641,GO:0042398,GO:0043043,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0051186,GO:0051188,GO:0070013,GO:0071704,GO:1901564,GO:1901566,GO:1901576 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000003088 224.0
PYH2_k127_7051622_7 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000000000000003713 186.0
PYH2_k127_7051622_8 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000532 140.0
PYH2_k127_7051622_9 methylamine metabolic process - - - 0.00000000000000000000000000000551 125.0
PYH2_k127_7058116_0 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.168e-283 891.0
PYH2_k127_7058116_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.506e-217 687.0
PYH2_k127_7058116_10 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 389.0
PYH2_k127_7058116_11 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 378.0
PYH2_k127_7058116_12 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 352.0
PYH2_k127_7058116_13 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006302 263.0
PYH2_k127_7058116_14 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004776 245.0
PYH2_k127_7058116_15 - - - - 0.00000000000000000000000000000000000000000013 165.0
PYH2_k127_7058116_16 negative regulation of transcription, DNA-templated K21600 - - 0.00000000000000000000000000000000002452 138.0
PYH2_k127_7058116_17 - - - - 0.00000000000000000000003035 110.0
PYH2_k127_7058116_18 Heavy metal-associated domain protein K07213 - - 0.0000000009315 62.0
PYH2_k127_7058116_19 Sugar (pentulose and hexulose) kinases - - - 0.0000001763 64.0
PYH2_k127_7058116_2 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.096e-196 629.0
PYH2_k127_7058116_3 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009123 608.0
PYH2_k127_7058116_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 612.0
PYH2_k127_7058116_5 L-rhamnose isomerase K01813 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0008150,GO:0008152,GO:0008740,GO:0009056,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0019299,GO:0019301,GO:0019318,GO:0019320,GO:0019321,GO:0019324,GO:0044238,GO:0044281,GO:0044282,GO:0046365,GO:0071704,GO:1901575 5.3.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 592.0
PYH2_k127_7058116_6 peptidase dimerisation domain protein K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 541.0
PYH2_k127_7058116_7 D-mannonate dehydratase (UxuA) K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 473.0
PYH2_k127_7058116_8 thiolester hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 469.0
PYH2_k127_7058116_9 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 428.0
PYH2_k127_7058511_0 Bacterial alpha-L-rhamnosidase C-terminal domain K05989 - 3.2.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 302.0
PYH2_k127_7058511_1 Converts 4-O-beta-D-mannopyranosyl-D-glucopyranose (Man- Glc) to mannose 1-phosphate (Man1P) and glucose - - - 0.000000000000000000000000000000000008897 140.0
PYH2_k127_7061663_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 2.058e-238 763.0
PYH2_k127_7061663_1 Domain present in PSD-95, Dlg, and ZO-1/2. K08070,K08372 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 317.0
PYH2_k127_7061663_10 Belongs to the ompA family K03640 - - 0.000000000000000000000000000001124 123.0
PYH2_k127_7061663_11 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000001032 131.0
PYH2_k127_7061663_12 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000000000000000003541 125.0
PYH2_k127_7061663_13 Glycoprotease family - - - 0.0000000000000000000000000001432 126.0
PYH2_k127_7061663_14 Involved in chromosome partitioning - - - 0.0000000000000000000000000002593 124.0
PYH2_k127_7061663_15 Outer membrane lipoprotein - - - 0.00000000000000000000001853 111.0
PYH2_k127_7061663_16 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000321 90.0
PYH2_k127_7061663_17 Belongs to the ompA family K03640 - - 0.00000000000000004841 87.0
PYH2_k127_7061663_18 Carboxymuconolactone decarboxylase family - - - 0.00000000493 62.0
PYH2_k127_7061663_19 energy transducer activity K03646,K03832 - - 0.000001714 59.0
PYH2_k127_7061663_2 WD40-like Beta Propeller K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001174 291.0
PYH2_k127_7061663_3 IstB-like ATP binding protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000169 230.0
PYH2_k127_7061663_4 MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000001115 192.0
PYH2_k127_7061663_5 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.000000000000000000000000000000000000000000001528 170.0
PYH2_k127_7061663_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000003757 163.0
PYH2_k127_7061663_7 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000008786 160.0
PYH2_k127_7061663_8 Ligated ion channel L-glutamate- and glycine-binding site K02030 - - 0.00000000000000000000000000000000000007407 156.0
PYH2_k127_7061663_9 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.00000000000000000000000000000000007608 138.0
PYH2_k127_7062880_0 beta-glucosidase 2, glycosyl-hydrolase family 116 N-term K17108 - 3.2.1.45 1.346e-310 977.0
PYH2_k127_7062880_1 Exodeoxyribonuclease V, gamma subunit K03583 - 3.1.11.5 2.672e-300 955.0
PYH2_k127_7062880_10 Ferric reductase like transmembrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000001832 235.0
PYH2_k127_7062880_11 acetyltransferase - - - 0.00000000000000000000000000000000000000000002477 172.0
PYH2_k127_7062880_12 - - - - 0.000000000000000000000000001857 113.0
PYH2_k127_7062880_13 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01179 - 3.2.1.4 0.000000000000000000000000422 113.0
PYH2_k127_7062880_14 Cna protein B-type domain - - - 0.00000003091 59.0
PYH2_k127_7062880_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 2.235e-277 894.0
PYH2_k127_7062880_3 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 571.0
PYH2_k127_7062880_4 Phosphoribulokinase / Uridine kinase family K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 559.0
PYH2_k127_7062880_5 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002726 437.0
PYH2_k127_7062880_6 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 331.0
PYH2_k127_7062880_7 NAD+ binding K12410 GO:0000726,GO:0003674,GO:0003824,GO:0003953,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006303,GO:0006464,GO:0006471,GO:0006476,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016787,GO:0016798,GO:0016799,GO:0019213,GO:0019538,GO:0030312,GO:0033554,GO:0033558,GO:0034641,GO:0034979,GO:0035601,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070213,GO:0071214,GO:0071478,GO:0071479,GO:0071704,GO:0071944,GO:0090304,GO:0098732,GO:0104004,GO:0140096,GO:1901360,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008842 292.0
PYH2_k127_7062880_8 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000006818 270.0
PYH2_k127_7062880_9 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000003065 275.0
PYH2_k127_7067074_0 efflux transmembrane transporter activity K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008209 285.0
PYH2_k127_7067074_1 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000001473 124.0
PYH2_k127_7067074_2 Smr domain - - - 0.0000000000000000000000000007078 123.0
PYH2_k127_7067074_3 Pterin binding enzyme K00796 - 2.5.1.15 0.000000002332 64.0
PYH2_k127_7067074_4 MerR family regulatory protein K19591 - - 0.0002223 43.0
PYH2_k127_7082498_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002155 403.0
PYH2_k127_7082498_1 - - - - 0.00000000000000000000000000000003576 136.0
PYH2_k127_7082498_2 PcfJ-like protein - - - 0.0007727 50.0
PYH2_k127_7087989_0 Sodium:solute symporter family K03307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 597.0
PYH2_k127_7087989_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 317.0
PYH2_k127_7087989_2 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 296.0
PYH2_k127_7087989_3 helix_turn_helix isocitrate lyase regulation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005635 271.0
PYH2_k127_7087989_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000003707 98.0
PYH2_k127_7098569_0 Oxidoreductase - - - 1.195e-226 711.0
PYH2_k127_7098569_1 Major Facilitator Superfamily K02445 - - 1.03e-201 637.0
PYH2_k127_7098569_10 Dienelactone hydrolase family - - - 0.00000000000000000000000000000000000000000000000001371 190.0
PYH2_k127_7098569_11 protein containing a von Willebrand factor type A (vWA) domain K07114 - - 0.0000000000000000000000000000000000000000000000002271 199.0
PYH2_k127_7098569_12 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000000002775 163.0
PYH2_k127_7098569_13 Converts the aldose L-fucose into the corresponding ketose L-fuculose - - - 0.0000000000000000000000000000000000000000006493 175.0
PYH2_k127_7098569_15 CinA-like protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000002019 154.0
PYH2_k127_7098569_16 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000000000000000000000000000006578 140.0
PYH2_k127_7098569_17 Carbon-nitrogen hydrolase - - - 0.00000000000000000000000000000006071 136.0
PYH2_k127_7098569_18 Domain of unknown function (DUF4349) - - - 0.00000000000000000000000000000006231 136.0
PYH2_k127_7098569_19 - - - - 0.00000000000000000000000000003243 122.0
PYH2_k127_7098569_2 Beta-galactosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 471.0
PYH2_k127_7098569_20 - - - - 0.000000000000000001077 95.0
PYH2_k127_7098569_21 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000001544 83.0
PYH2_k127_7098569_22 helix_turn_helix, mercury resistance - - - 0.0000000000322 70.0
PYH2_k127_7098569_23 Beta-galactosidase - - - 0.00003292 49.0
PYH2_k127_7098569_3 COGs COG4299 conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000599 418.0
PYH2_k127_7098569_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 395.0
PYH2_k127_7098569_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 364.0
PYH2_k127_7098569_6 Uncharacterized alpha/beta hydrolase domain (DUF2235) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 360.0
PYH2_k127_7098569_7 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 307.0
PYH2_k127_7098569_8 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001578 280.0
PYH2_k127_7098569_9 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002713 277.0
PYH2_k127_7120629_0 PFAM D-aminoacylase, C-terminal region K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 603.0
PYH2_k127_7120629_1 Domain of Unknown Function (DUF1080) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 389.0
PYH2_k127_7120629_10 cyclic nucleotide binding K00384,K01999,K07001,K10914 - 1.8.1.9 0.0000000000000000000000006995 109.0
PYH2_k127_7120629_11 Tetratricopeptide repeat - - - 0.00000000000000000000000129 117.0
PYH2_k127_7120629_12 ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000003723 91.0
PYH2_k127_7120629_13 PFAM Surface antigen variable number repeat K07277 - - 0.0000007363 61.0
PYH2_k127_7120629_14 response regulator, receiver - - - 0.0006811 46.0
PYH2_k127_7120629_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008129 265.0
PYH2_k127_7120629_3 lyase activity K03301 - - 0.000000000000000000000000000000000000000000000000000000000004313 236.0
PYH2_k127_7120629_4 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000001825 216.0
PYH2_k127_7120629_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03406,K21009 - - 0.0000000000000000000000000000000000000000000000007673 188.0
PYH2_k127_7120629_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000006644 173.0
PYH2_k127_7120629_7 PFAM response regulator receiver - - - 0.000000000000000000000000000000000000001214 156.0
PYH2_k127_7120629_8 Acid phosphatase homologues - - - 0.000000000000000000000000000002133 130.0
PYH2_k127_7120629_9 Periplasmic binding protein K01999 - - 0.00000000000000000000000000003147 136.0
PYH2_k127_7143531_0 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002721 350.0
PYH2_k127_7143531_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02035 - - 0.00000000000000000000000000000000000000000000000000003094 209.0
PYH2_k127_7143531_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000176 96.0
PYH2_k127_7155331_0 HTH-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 408.0
PYH2_k127_7155331_1 DNA integration K14059 - - 0.00000000000000000000000000000000000000000000000000000000004036 217.0
PYH2_k127_7155331_2 Transposase - - - 0.0000000000000000000000000000000000000089 146.0
PYH2_k127_7155331_3 Galactose oxidase, central domain - - - 0.000000000955 61.0
PYH2_k127_7155331_4 Belongs to the 'phage' integrase family K14059 - - 0.0000005155 55.0
PYH2_k127_7175622_0 PFAM TM1410 hypothetical-related protein K21006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 591.0
PYH2_k127_7175622_1 beta-galactosidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003457 320.0
PYH2_k127_7175622_2 Glycoside-hydrolase family GH114 K21006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005202 291.0
PYH2_k127_7175622_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000002897 243.0
PYH2_k127_7175622_4 chaperone-mediated protein folding K11935 - - 0.000000000000004682 79.0
PYH2_k127_7212844_0 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 302.0
PYH2_k127_7212844_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000006636 226.0
PYH2_k127_7212844_2 MoaE protein K21142 - 2.8.1.12 0.00000000000000000000000000000000000000695 152.0
PYH2_k127_7212844_3 Glucose dehydrogenase C-terminus K00008,K05351 - 1.1.1.14,1.1.1.9 0.000000000000000000000000000003073 126.0
PYH2_k127_7212844_4 MoaE protein K21142 - 2.8.1.12 0.00000000000000004404 83.0
PYH2_k127_7212844_5 Histone methylation protein DOT1 - - - 0.00002856 46.0
PYH2_k127_7216240_0 Carboxypeptidase regulatory-like domain - - - 3.995e-318 1012.0
PYH2_k127_7216240_1 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111,K01153 - 1.1.5.3,3.1.21.3 5.508e-304 948.0
PYH2_k127_7216240_10 Protein of unknown function (DUF3748) - - - 0.0004358 48.0
PYH2_k127_7216240_2 - - - - 6.771e-233 739.0
PYH2_k127_7216240_3 cell adhesion involved in biofilm formation - - - 1.366e-212 692.0
PYH2_k127_7216240_4 Alpha-L-fucosidase K01206 - 3.2.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002773 503.0
PYH2_k127_7216240_5 Belongs to the glycosyl hydrolase 32 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009137 436.0
PYH2_k127_7216240_6 Sugar (and other) transporter K08191 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 415.0
PYH2_k127_7216240_7 Glycosyl hydrolases family 16 K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000002624 237.0
PYH2_k127_7216240_8 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00000000000000000000000000000000001712 140.0
PYH2_k127_7216240_9 COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000003021 89.0
PYH2_k127_7221643_0 PFAM Transposase, IS204 IS1001 IS1096 IS1165 K07485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004228 454.0
PYH2_k127_7221643_1 Integrase - - - 0.000000000000000000000000000000000000000000000000000002509 202.0
PYH2_k127_7221643_2 Integrase - - - 0.0000000000000000006871 88.0
PYH2_k127_7249464_0 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000001036 200.0
PYH2_k127_7250394_0 2-methylcitrate dehydratase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 401.0
PYH2_k127_7250394_1 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 323.0
PYH2_k127_7250394_2 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006215 277.0
PYH2_k127_7250394_3 - - - - 0.00006179 45.0
PYH2_k127_7308265_0 Periplasmic binding protein-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000701 261.0
PYH2_k127_7308265_1 Bacterial extracellular solute-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000009628 238.0
PYH2_k127_7308265_2 PFAM binding-protein-dependent transport systems inner membrane component K10189,K10241,K17235 - - 0.00000000000000000000000000005398 121.0
PYH2_k127_7327869_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 447.0
PYH2_k127_7327869_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002396 267.0
PYH2_k127_7327869_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000001297 219.0
PYH2_k127_7327869_3 - - - - 0.00000000000009588 72.0
PYH2_k127_7327869_4 - - - - 0.0000000005422 59.0
PYH2_k127_7348065_0 inositol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 375.0
PYH2_k127_7348065_1 myo-inosose-2 dehydratase activity K03335,K15652 - 4.2.1.118,4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000004387 229.0
PYH2_k127_7348754_0 Phosphoglucose isomerase K01810 - 5.3.1.9 5.953e-297 917.0
PYH2_k127_7348754_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 355.0
PYH2_k127_7348754_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 320.0
PYH2_k127_7348754_3 DinB family - - - 0.0000000000000000000000000000000000000003029 154.0
PYH2_k127_7348754_4 - - - - 0.00000000000000000000000000000000001848 139.0
PYH2_k127_7348754_5 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000004341 145.0
PYH2_k127_7348754_6 - - - - 0.0000000000000002513 85.0
PYH2_k127_7348754_7 CarboxypepD_reg-like domain - - - 0.0000003775 54.0
PYH2_k127_7348754_8 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.0005913 44.0
PYH2_k127_734981_0 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 447.0
PYH2_k127_734981_1 Protein of unknown function (DUF1501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006627 333.0
PYH2_k127_7354021_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 426.0
PYH2_k127_7354021_1 Beta-lactamase - - - 0.000000000000000000000000000000000005059 140.0
PYH2_k127_7358901_0 all-trans-retinol 13,14-reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007532 461.0
PYH2_k127_7358901_1 Protein kinase domain K12132 - 2.7.11.1 0.000002104 50.0
PYH2_k127_7371501_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000002411 153.0
PYH2_k127_7371501_1 energy transducer activity K02487,K03832,K06596 - - 0.000000000000000000004119 104.0
PYH2_k127_7371501_2 Protein of unknown function (DUF2911) - - - 0.000000000000006021 82.0
PYH2_k127_7371501_3 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000961 71.0
PYH2_k127_7371501_4 WD40 domain protein beta Propeller - - - 0.000000001935 67.0
PYH2_k127_7378662_0 helicase superfamily c-terminal domain K03654 - 3.6.4.12 1.8e-243 771.0
PYH2_k127_7378662_1 Glycosyl hydrolase family 10 K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004765 455.0
PYH2_k127_7378662_2 Carbohydrate family 9 binding domain-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008804 432.0
PYH2_k127_7378662_3 Mandelate racemase muconate lactonizing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001001 273.0
PYH2_k127_7378662_4 Rossmann fold nucleotide-binding protein involved in DNA uptake - - - 0.0000000000000000000000000000000000000000000000000000000000000004965 234.0
PYH2_k127_7378662_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000005459 202.0
PYH2_k127_7378662_6 PFAM Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000004813 173.0
PYH2_k127_7378662_7 Metallo-beta-lactamase superfamily - - - 0.00000000000000008592 90.0
PYH2_k127_7406105_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 575.0
PYH2_k127_7406105_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005213 507.0
PYH2_k127_7406105_10 Chorismate mutase type II K04093 - 5.4.99.5 0.0000000000000000000004741 98.0
PYH2_k127_7406105_2 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 486.0
PYH2_k127_7406105_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 299.0
PYH2_k127_7406105_4 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000007561 268.0
PYH2_k127_7406105_5 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000002287 264.0
PYH2_k127_7406105_6 Belongs to the TrpC family K01609 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000007184 229.0
PYH2_k127_7406105_7 PFAM Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000002707 210.0
PYH2_k127_7406105_8 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 - 3.5.1.9 0.00000000000000000000000000000000000000000000000001014 186.0
PYH2_k127_7406105_9 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000004602 185.0
PYH2_k127_7410394_0 Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein) - - - 0.000000000000000000000000000000000000000000000000000000000000000001929 245.0
PYH2_k127_7410394_1 IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000462 166.0
PYH2_k127_7410394_3 - - - - 0.0000000000001419 78.0
PYH2_k127_7410394_4 DNA integration - - - 0.00000000002045 71.0
PYH2_k127_7410394_5 Belongs to the 'phage' integrase family - - - 0.000002317 53.0
PYH2_k127_74150_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003797 574.0
PYH2_k127_74150_1 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 316.0
PYH2_k127_74150_2 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 294.0
PYH2_k127_74150_3 Yip1 domain - - - 0.0000000000000202 82.0
PYH2_k127_74150_4 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.000000000003411 74.0
PYH2_k127_7415943_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K19686 - - 0.0000000000000000000000000000000000000000000004326 169.0
PYH2_k127_7415943_1 family 2 sugar binding - - - 0.000000000000000000000000001357 117.0
PYH2_k127_7415943_2 Rv0623-like transcription factor K19687 - - 0.00000000000000000000000003013 109.0
PYH2_k127_7415943_3 Bacterial alpha-L-rhamnosidase C-terminal domain - - - 0.000000005857 58.0
PYH2_k127_7477565_0 TIGRFAM Tat (twin-arginine translocation) pathway signal sequence - - - 1.097e-234 736.0
PYH2_k127_7477565_1 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007323 408.0
PYH2_k127_7477565_2 Ferritin Dps family protein K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000103 245.0
PYH2_k127_7477565_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000004902 93.0
PYH2_k127_7477565_4 Transglycosylase-like domain K21687 - - 0.00000000000009398 85.0
PYH2_k127_7477565_5 PFAM oxidoreductase domain protein - - - 0.00006219 47.0
PYH2_k127_7477712_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 3.1e-322 998.0
PYH2_k127_7477712_1 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 2.687e-194 632.0
PYH2_k127_7477712_2 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008288 337.0
PYH2_k127_7477712_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 321.0
PYH2_k127_7477712_4 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000236 258.0
PYH2_k127_7477712_5 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000006014 229.0
PYH2_k127_7477712_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000001046 227.0
PYH2_k127_7477712_7 PFAM single-strand binding protein Primosomal replication protein n K03111 - - 0.000000000000000000000000000000005782 131.0
PYH2_k127_7477712_8 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000239 125.0
PYH2_k127_7477712_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000008761 80.0
PYH2_k127_7479158_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005148 271.0
PYH2_k127_7479158_1 helix_turn_helix, Lux Regulon K02282 - - 0.00000000000000000000000000000000000000000000000000000000001846 215.0
PYH2_k127_7479158_2 PFAM response regulator receiver - - - 0.000000000000000000000000000000008297 135.0
PYH2_k127_7479158_3 PFAM Signal transduction response regulator, chemotaxis, protein-glutamate methylesterase K13924 - 2.1.1.80,3.1.1.61 0.0000000000000091 89.0
PYH2_k127_7500555_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008987 480.0
PYH2_k127_7500555_1 Large family of predicted nucleotide-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 318.0
PYH2_k127_7500555_2 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 313.0
PYH2_k127_7500555_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000001716 138.0
PYH2_k127_7506710_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001908 478.0
PYH2_k127_7506710_1 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.00000000000000000000000000000000001782 142.0
PYH2_k127_7506710_2 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.000000000000000000000000000000000137 137.0
PYH2_k127_751889_0 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 348.0
PYH2_k127_751889_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 332.0
PYH2_k127_751889_2 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000006002 181.0
PYH2_k127_751889_3 structural constituent of ribosome K02996 - - 0.00000000000000000000000000000000000000000002619 164.0
PYH2_k127_751889_4 Pilus assembly protein, PilO K02664 - - 0.00000000211 66.0
PYH2_k127_751889_6 PFAM Fimbrial assembly family protein K02663 - - 0.00000002526 63.0
PYH2_k127_751889_7 Secretin and TonB N terminus short domain K02666 - - 0.0000003045 59.0
PYH2_k127_7519729_0 Carboxypeptidase regulatory-like domain - - - 2.371e-202 667.0
PYH2_k127_7519729_1 Domain of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000012 215.0
PYH2_k127_7519729_2 TonB-dependent receptor - - - 0.00000001038 64.0
PYH2_k127_7526965_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007166 479.0
PYH2_k127_7526965_1 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000009626 242.0
PYH2_k127_7526965_2 Transposase and inactivated derivatives - - - 0.00000000000000000005144 93.0
PYH2_k127_7526965_3 Integrase catalytic K07497 - - 0.0000000000008622 74.0
PYH2_k127_7526965_4 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000003731 67.0
PYH2_k127_7529836_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000007435 213.0
PYH2_k127_7529836_1 Domain of unknown function (DUF4091) - - - 0.0000000000000000000000000000000000000000000000000000001133 220.0
PYH2_k127_7533755_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 304.0
PYH2_k127_7533755_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K07124 - - 0.000000000000000000000000000000000000000000000000000000000000000000001897 241.0
PYH2_k127_7533755_3 Domain of Unknown Function (DUF1080) - - - 0.000000000000000000000000000000000000000000000000000000000000000005296 239.0
PYH2_k127_7533755_4 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000001848 176.0
PYH2_k127_7533755_5 Carbohydrate family 9 binding domain-like - - - 0.00000000000000000000000000000000000002501 153.0
PYH2_k127_7533755_6 Hep Hag repeat protein - - - 0.0000000000000000000000009618 121.0
PYH2_k127_7533755_7 23S rRNA-intervening sequence protein - - - 0.00009331 47.0
PYH2_k127_7540637_0 TIGRFAM type VI secretion system Vgr family protein K11904 - - 1.501e-232 744.0
PYH2_k127_7540637_1 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 2.294e-199 629.0
PYH2_k127_7540637_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 583.0
PYH2_k127_7540637_3 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007588 412.0
PYH2_k127_7540637_4 Prephenate dehydratase K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 356.0
PYH2_k127_7540637_5 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000004685 227.0
PYH2_k127_7540637_6 Putative peptidoglycan binding domain - - - 0.000000000000000000000000000000000000000000000000006003 189.0
PYH2_k127_7540637_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000174 127.0
PYH2_k127_7540637_8 23S rRNA-intervening sequence protein - - - 0.000000000005319 68.0
PYH2_k127_7545686_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 7.082e-262 816.0
PYH2_k127_7545686_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006327 598.0
PYH2_k127_7545686_10 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000000000000000000000000000003478 151.0
PYH2_k127_7545686_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000000006853 137.0
PYH2_k127_7545686_12 PFAM Colicin V production K03558 - - 0.00000000000000000002344 99.0
PYH2_k127_7545686_14 Bacterial regulatory protein, Fis family - - - 0.000005772 51.0
PYH2_k127_7545686_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 434.0
PYH2_k127_7545686_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 428.0
PYH2_k127_7545686_4 SAICAR synthetase K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 385.0
PYH2_k127_7545686_5 SpoIVB peptidase S55 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 381.0
PYH2_k127_7545686_6 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006739 349.0
PYH2_k127_7545686_7 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000005271 241.0
PYH2_k127_7545686_8 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000003022 222.0
PYH2_k127_7545686_9 PHP domain K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000002658 212.0
PYH2_k127_7551718_0 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 610.0
PYH2_k127_7551718_1 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 406.0
PYH2_k127_7551718_10 PFAM Protein kinase domain K00870 - 2.7.1.37 0.0003638 46.0
PYH2_k127_7551718_11 Flagellar basal body rod protein - - - 0.0007801 47.0
PYH2_k127_7551718_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001513 280.0
PYH2_k127_7551718_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000003783 238.0
PYH2_k127_7551718_4 Glycosyl transferase, family 2 K00721,K01912,K08301 - 2.4.1.83,6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000006482 230.0
PYH2_k127_7551718_5 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000001983 220.0
PYH2_k127_7551718_6 cell redox homeostasis K00384,K12057,K12267,K21636 - 1.1.98.6,1.8.1.9,1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000001978 204.0
PYH2_k127_7551718_7 iron-sulfur cluster assembly K07400 - - 0.00000000000000000000000000000000000000000009579 168.0
PYH2_k127_7551718_8 Bacterial DNA-binding protein K03530 - - 0.0000000000000000000000000000004831 124.0
PYH2_k127_7554985_0 Enolase C-terminal domain-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 573.0
PYH2_k127_7554985_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000003089 211.0
PYH2_k127_7554985_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000127 150.0
PYH2_k127_7558879_0 Pyridoxal-dependent decarboxylase conserved domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009416 583.0
PYH2_k127_7558879_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 490.0
PYH2_k127_7558879_10 Fungalysin metallopeptidase (M36) - - - 0.000000000000000001404 101.0
PYH2_k127_7558879_11 OmpA family - - - 0.000000000003461 80.0
PYH2_k127_7558879_12 23S rRNA-intervening sequence protein - - - 0.000003861 51.0
PYH2_k127_7558879_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003329 366.0
PYH2_k127_7558879_3 amine dehydrogenase activity K14647,K21449 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006545 358.0
PYH2_k127_7558879_4 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 315.0
PYH2_k127_7558879_5 Insulinase (Peptidase family M16) K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 325.0
PYH2_k127_7558879_6 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002938 308.0
PYH2_k127_7558879_7 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000004756 265.0
PYH2_k127_7558879_8 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001407 282.0
PYH2_k127_7558879_9 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000008619 110.0
PYH2_k127_7558916_0 TonB-dependent receptor - - - 3.125e-219 718.0
PYH2_k127_7567536_0 B12 binding domain K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1669.0
PYH2_k127_7567536_1 UTP--glucose-1-phosphate uridylyltransferase - - - 0.0 1150.0
PYH2_k127_7567536_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 455.0
PYH2_k127_7567536_3 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 363.0
PYH2_k127_7567536_4 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009787 292.0
PYH2_k127_7567536_5 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000001367 200.0
PYH2_k127_7582487_0 PFAM Cytochrome c assembly protein K02198 - - 2.889e-202 649.0
PYH2_k127_7582487_1 Metallopeptidase family M24 K01262,K01271 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.4.11.9,3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 446.0
PYH2_k127_7582487_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 351.0
PYH2_k127_7582487_3 ABC-type transport system involved in cytochrome c biogenesis, permease component K02195 - - 0.000000000000000000000000000000000000000000000000000000000000009041 222.0
PYH2_k127_7582487_4 PFAM ABC transporter related K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000001347 186.0
PYH2_k127_7582487_5 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000007682 183.0
PYH2_k127_7582487_7 - - - - 0.000000000000782 74.0
PYH2_k127_7582487_8 - - - - 0.000000001775 70.0
PYH2_k127_7582487_9 subunit of a heme lyase K02198,K02200 - - 0.00000001012 63.0
PYH2_k127_7590487_0 PFAM natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 490.0
PYH2_k127_7590487_1 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007481 288.0
PYH2_k127_7590487_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000718 275.0
PYH2_k127_7590487_3 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 260.0
PYH2_k127_7590487_4 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003539 254.0
PYH2_k127_7590487_5 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000002383 167.0
PYH2_k127_7590487_7 Belongs to the 'phage' integrase family - - - 0.00000000000000001799 86.0
PYH2_k127_7604521_0 PIN domain - - - 0.00000000000000000000000000000000000000000001596 165.0
PYH2_k127_7604521_1 positive regulation of growth K01081 - 3.1.3.5 0.00000000000000000000006061 100.0
PYH2_k127_7604521_2 Integrase core domain - - - 0.0000000000000000005945 95.0
PYH2_k127_7604521_3 L,D-transpeptidase catalytic domain - - - 0.0000000000023 71.0
PYH2_k127_7604521_4 PFAM Transposase_11 - - - 0.0000161 53.0
PYH2_k127_7608047_0 radical SAM domain protein - - - 3.832e-276 861.0
PYH2_k127_7608047_1 inositol 2-dehydrogenase activity - - - 2.97e-196 616.0
PYH2_k127_7608047_10 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000000000000000001006 167.0
PYH2_k127_7608047_11 Putative stress-induced transcription regulator - - - 0.0000000000000000000000000000000000001229 147.0
PYH2_k127_7608047_12 DinB family - - - 0.000000000000000000000000000000000006603 142.0
PYH2_k127_7608047_13 - - - - 0.000000000000000000001002 96.0
PYH2_k127_7608047_14 - - - - 0.000000000000004571 80.0
PYH2_k127_7608047_15 TfoX N-terminal domain - - - 0.00000000000002515 76.0
PYH2_k127_7608047_16 Met-10+ like-protein - - - 0.00000000000006882 76.0
PYH2_k127_7608047_17 - - - - 0.00000002012 59.0
PYH2_k127_7608047_18 Protein of unknown function (DUF1697) - - - 0.0000004715 59.0
PYH2_k127_7608047_2 COG3119 Arylsulfatase A and related enzymes K01134 - 3.1.6.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 464.0
PYH2_k127_7608047_3 UDP-4-amino-4-deoxy-L-arabinose aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 392.0
PYH2_k127_7608047_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 330.0
PYH2_k127_7608047_5 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 332.0
PYH2_k127_7608047_6 glutamine-fructose-6-phosphate transaminase (isomerizing) activity K00820 - 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 310.0
PYH2_k127_7608047_7 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006359 288.0
PYH2_k127_7608047_8 RibD C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000001019 226.0
PYH2_k127_7608047_9 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000006132 177.0
PYH2_k127_7625756_0 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.000000000000000000000000000000000001034 139.0
PYH2_k127_7637423_0 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000002337 201.0
PYH2_k127_7637423_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000007901 164.0
PYH2_k127_7637423_2 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000001518 141.0
PYH2_k127_7637423_3 Metallo-peptidase family M12 - - - 0.00000000214 66.0
PYH2_k127_7637423_4 - - - - 0.00000002877 61.0
PYH2_k127_7646441_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 580.0
PYH2_k127_7646441_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 480.0
PYH2_k127_7646441_10 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 368.0
PYH2_k127_7646441_11 Methane oxygenase PmoA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 321.0
PYH2_k127_7646441_12 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 331.0
PYH2_k127_7646441_13 Beta-galactosidase trimerisation domain K12308 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000003433 238.0
PYH2_k127_7646441_14 OsmC-like protein - - - 0.00000000000000000000000000000000000000000001112 165.0
PYH2_k127_7646441_15 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000008608 169.0
PYH2_k127_7646441_16 oxidation-reduction process - - - 0.000000000000000000000000000000000002367 153.0
PYH2_k127_7646441_17 - - - - 0.0000000000000000000000000000000004785 136.0
PYH2_k127_7646441_18 cAMP biosynthetic process - - - 0.000000000000000000000000000000103 140.0
PYH2_k127_7646441_2 FAD dependent oxidoreductase K00109,K15736 - 1.1.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 460.0
PYH2_k127_7646441_3 Major facilitator superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008933 461.0
PYH2_k127_7646441_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 447.0
PYH2_k127_7646441_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 428.0
PYH2_k127_7646441_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 427.0
PYH2_k127_7646441_7 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007892 419.0
PYH2_k127_7646441_8 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 400.0
PYH2_k127_7646441_9 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 382.0
PYH2_k127_7648537_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1699.0
PYH2_k127_7648537_1 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 0.0 1395.0
PYH2_k127_7648537_10 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 286.0
PYH2_k127_7648537_11 Response regulator receiver - - - 0.000000000000000000000000000000000000000000006443 167.0
PYH2_k127_7648537_12 cheY-homologous receiver domain K11443 - - 0.000000000000000000000000000000000000000000007716 165.0
PYH2_k127_7648537_13 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000007676 70.0
PYH2_k127_7648537_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000002561 70.0
PYH2_k127_7648537_15 Acetyltransferase K00661 - 2.3.1.79 0.00000001832 64.0
PYH2_k127_7648537_16 Tetratricopeptide repeat - - - 0.00002895 55.0
PYH2_k127_7648537_2 MacB-like periplasmic core domain - - - 7.727e-275 867.0
PYH2_k127_7648537_3 Succinyl-CoA ligase like flavodoxin domain - - - 1.519e-227 735.0
PYH2_k127_7648537_4 COGs COG5001 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 5.035e-200 646.0
PYH2_k127_7648537_5 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 614.0
PYH2_k127_7648537_6 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 572.0
PYH2_k127_7648537_7 Amidohydrolase family K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003228 550.0
PYH2_k127_7648537_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 515.0
PYH2_k127_7648537_9 Putative serine dehydratase domain K01753 - 4.3.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 320.0
PYH2_k127_7649634_0 Tex-like protein N-terminal domain K06959 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 534.0
PYH2_k127_7649634_1 Dihydroorotate dehydrogenase K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008874 486.0
PYH2_k127_7649634_2 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000217 301.0
PYH2_k127_7649634_3 ABC transporter K01990,K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003456 271.0
PYH2_k127_7649634_4 ABC-2 family transporter protein K01992,K07052,K09696 - - 0.00000000000000000000000000000000000000000000000003747 202.0
PYH2_k127_7649634_5 multi-organism process - - - 0.000000000000000000000000000000000002571 149.0
PYH2_k127_7649634_6 ABC-2 family transporter protein K01992,K09696 - - 0.0000000000000000000000000000000000426 149.0
PYH2_k127_7649634_7 spore germination K03605 - - 0.0004217 42.0
PYH2_k127_7673835_0 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.0000000000000000000000000000000000000000000000000418 201.0
PYH2_k127_7673835_1 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.0000000000000000000000000000001498 128.0
PYH2_k127_7673835_2 Flagellar protein FliS K02422 - - 0.0000000000000000000003931 101.0
PYH2_k127_7673835_3 Could accelerate the degradation of some genes transcripts potentially through selective RNA binding K03563 - - 0.00000000000006455 73.0
PYH2_k127_7673835_4 Chemotaxis phosphatase CheX K03409 - - 0.0000000000001562 77.0
PYH2_k127_7739137_0 ABC transporter K15738 - - 1.23e-232 728.0
PYH2_k127_7739137_1 dipeptidase activity - - - 4.023e-229 721.0
PYH2_k127_7739137_2 succinylglutamate desuccinylase aspartoacylase K06987,K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006309 596.0
PYH2_k127_7739137_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003161 542.0
PYH2_k127_7739137_4 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 535.0
PYH2_k127_7739137_5 - - - - 0.00000000000000000000000000000000000000000000000001369 188.0
PYH2_k127_7739137_6 - - - - 0.00008055 46.0
PYH2_k127_7741072_0 PFAM Uncharacterised BCR, COG1649 K05988 - 3.2.1.11 0.000000000000000000000000003264 126.0
PYH2_k127_7741072_1 Transporter, major facilitator family protein K08191 - - 0.00000000119 60.0
PYH2_k127_7747266_0 HELICc2 K03722 - 3.6.4.12 5.673e-201 646.0
PYH2_k127_7747266_1 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000001084 211.0
PYH2_k127_7747266_2 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.000000000000000000000000000000000000000005825 160.0
PYH2_k127_7747266_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000005764 156.0
PYH2_k127_7747266_4 Tetratricopeptide repeat - - - 0.00000000000000000000007969 106.0
PYH2_k127_7747266_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.00007002 48.0
PYH2_k127_7761568_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1123.0
PYH2_k127_7761568_1 glycyl-tRNA synthetase, tetrameric type, beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 511.0
PYH2_k127_7761568_10 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000008509 145.0
PYH2_k127_7761568_11 Belongs to the bacterial histone-like protein family K03530 - - 0.0000000000000000000000000000000009817 132.0
PYH2_k127_7761568_12 Involved in DNA repair and RecF pathway recombination K03474,K03584 GO:0008150,GO:0009314,GO:0009628,GO:0050896 2.6.99.2 0.00000000000000000000000000000247 129.0
PYH2_k127_7761568_13 Lipopolysaccharide-assembly - - - 0.0000000000000000000000000834 113.0
PYH2_k127_7761568_14 PFAM GGDEF domain containing protein - - - 0.00000000000000002315 85.0
PYH2_k127_7761568_15 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000009938 63.0
PYH2_k127_7761568_16 Protein of unknown function (DUF465) - - - 0.000000005736 60.0
PYH2_k127_7761568_17 - - - - 0.0001496 44.0
PYH2_k127_7761568_2 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 420.0
PYH2_k127_7761568_3 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 364.0
PYH2_k127_7761568_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 365.0
PYH2_k127_7761568_5 dUTP biosynthetic process K01494 GO:0003674,GO:0003824,GO:0006139,GO:0006220,GO:0006244,GO:0006253,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008829,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009166,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009223,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019239,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046065,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000007016 232.0
PYH2_k127_7761568_6 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000003964 222.0
PYH2_k127_7761568_7 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000462 191.0
PYH2_k127_7761568_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000004308 188.0
PYH2_k127_7761568_9 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000001038 191.0
PYH2_k127_7800325_0 Pkd domain containing protein - - - 4.205e-210 691.0
PYH2_k127_7800325_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000001851 159.0
PYH2_k127_7800325_2 - - - - 0.000001016 57.0
PYH2_k127_7807861_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 4.069e-241 766.0
PYH2_k127_7807861_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 407.0
PYH2_k127_7807861_2 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000007967 136.0
PYH2_k127_7807861_3 Cytochrome c3 - - - 0.000000002647 64.0
PYH2_k127_7807861_4 Cupin domain - - - 0.0000006146 59.0
PYH2_k127_7811487_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007631 267.0
PYH2_k127_7811487_1 ABC-type sugar transport system periplasmic component K02027 - - 0.00000000000000000000000000002211 128.0
PYH2_k127_7811487_2 Haloacid dehalogenase-like hydrolase - - - 0.00007088 48.0
PYH2_k127_7814817_0 transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008188 564.0
PYH2_k127_7814817_1 polygalacturonase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007533 564.0
PYH2_k127_7814817_2 Amidohydrolase K07045 - - 0.0000000000000000000000000572 119.0
PYH2_k127_7814817_3 Phosphodiester glycosidase - - - 0.00001544 59.0
PYH2_k127_7830585_0 ATPase activity K01990,K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 334.0
PYH2_k127_7830585_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 320.0
PYH2_k127_7830585_2 - K01992,K19341 - - 0.000000000000000000000000000000000000000005467 165.0
PYH2_k127_7830585_3 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000006157 141.0
PYH2_k127_7839669_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 299.0
PYH2_k127_7839669_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000001769 191.0
PYH2_k127_7839669_2 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000003031 172.0
PYH2_k127_7839669_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000002072 126.0
PYH2_k127_7839669_4 pilus assembly protein PilW K02672 - - 0.0000001716 61.0
PYH2_k127_7851525_0 Glycogen debranching enzyme K05989 - 3.2.1.40 0.0 1206.0
PYH2_k127_7851525_1 drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 583.0
PYH2_k127_7851525_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001166 291.0
PYH2_k127_7851525_3 Biotin-lipoyl like K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003802 289.0
PYH2_k127_7851525_4 Involved in the tonB-independent uptake of proteins K01730,K03641 - 4.2.2.6 0.000000000000000000000000000000000000000000000000000000000000000000001459 250.0
PYH2_k127_7851525_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000002776 91.0
PYH2_k127_7851525_6 - - - - 0.000000006504 67.0
PYH2_k127_7851993_0 glucuronate isomerase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 452.0
PYH2_k127_7851993_1 glycerol channel activity K09876,K09877,K09886,K10404 GO:0002376,GO:0003674,GO:0005215,GO:0005372,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006833,GO:0006950,GO:0006952,GO:0006955,GO:0008150,GO:0008643,GO:0009605,GO:0009607,GO:0009617,GO:0015250,GO:0015267,GO:0015318,GO:0015791,GO:0015793,GO:0015850,GO:0016020,GO:0016323,GO:0022803,GO:0022838,GO:0022857,GO:0042044,GO:0042742,GO:0043207,GO:0044425,GO:0044459,GO:0044464,GO:0045087,GO:0050829,GO:0050896,GO:0051179,GO:0051234,GO:0051704,GO:0051707,GO:0055085,GO:0071702,GO:0071944,GO:0098542,GO:0098590 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 289.0
PYH2_k127_7851993_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000004375 238.0
PYH2_k127_7851993_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000001613 230.0
PYH2_k127_7851993_4 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000008731 216.0
PYH2_k127_7851993_5 Putative adhesin - - - 0.000000000000000000000000000000000000000000007504 176.0
PYH2_k127_7851993_6 Methane oxygenase PmoA - - - 0.0000000000000001428 91.0
PYH2_k127_7851993_7 Trehalose utilisation K01183,K09992 - 3.2.1.14 0.00001091 48.0
PYH2_k127_7870690_0 C-terminal, D2-small domain, of ClpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 439.0
PYH2_k127_7891683_0 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003802 530.0
PYH2_k127_7891683_1 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000009538 223.0
PYH2_k127_7891683_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000001166 220.0
PYH2_k127_7891683_3 signal transduction protein - - - 0.000000000000000000000000000000001273 141.0
PYH2_k127_7894858_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 404.0
PYH2_k127_7894858_1 NAD(P)H dehydrogenase (quinone) activity K03809 GO:0000166,GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0010181,GO:0016043,GO:0016491,GO:0016651,GO:0016655,GO:0022607,GO:0032553,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000001324 245.0
PYH2_k127_7894858_2 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000005097 190.0
PYH2_k127_7894858_3 - - - - 0.0000000000000000000000000008982 116.0
PYH2_k127_7894858_4 - - - - 0.0000000000000000004221 94.0
PYH2_k127_7894858_5 PFAM Integral membrane protein TerC K05794 - - 0.000000000000005557 78.0
PYH2_k127_7915190_0 PFAM oxidoreductase domain protein - - - 3.722e-203 641.0
PYH2_k127_7915190_1 Glycosyl hydrolases family 2 K15855 - 3.2.1.165 0.000000000000000000000000000000000000000000000000000000000000000007353 234.0
PYH2_k127_7915190_2 - - - - 0.0000000000000000000000000007893 116.0
PYH2_k127_7915190_3 - - - - 0.00000000007357 65.0
PYH2_k127_7938651_0 PFAM N-acetylneuraminic acid synthase K01654,K18430 - 2.5.1.101,2.5.1.56 0.0000000000000000000000000000000000000000000001181 174.0
PYH2_k127_7938651_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.000000000000000000000000000000000002888 147.0
PYH2_k127_7938651_2 Spore Coat - - - 0.000000000000000000002356 107.0
PYH2_k127_7938651_3 - - - - 0.00000002013 64.0
PYH2_k127_7941246_0 serine-type peptidase activity K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 387.0
PYH2_k127_7941246_1 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000035 258.0
PYH2_k127_7941246_2 Tricorn protease PDZ domain K08676 - - 0.00000000000000001446 99.0
PYH2_k127_7949783_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 2.073e-283 880.0
PYH2_k127_7949783_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009935 547.0
PYH2_k127_7949783_10 PD-(D/E)XK nuclease superfamily K07465 - - 0.000009038 57.0
PYH2_k127_7949783_2 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 402.0
PYH2_k127_7949783_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 308.0
PYH2_k127_7949783_4 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 293.0
PYH2_k127_7949783_5 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000009289 260.0
PYH2_k127_7949783_6 ERF superfamily - - - 0.00000000000000000000000000000000000000000000002497 179.0
PYH2_k127_7949783_7 DNA integration K14059 - - 0.00000000000000000000000000000000000003731 157.0
PYH2_k127_7949783_8 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.000000000000000000001853 98.0
PYH2_k127_7949783_9 - - - - 0.000000006915 62.0
PYH2_k127_7966019_0 PFAM Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 460.0
PYH2_k127_7966019_1 PFAM IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001279 274.0
PYH2_k127_7966019_3 Integrase - - - 0.0000000001788 62.0
PYH2_k127_7970256_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.108e-309 968.0
PYH2_k127_7970256_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.031e-290 914.0
PYH2_k127_7970256_10 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 472.0
PYH2_k127_7970256_11 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 436.0
PYH2_k127_7970256_12 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 332.0
PYH2_k127_7970256_13 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 336.0
PYH2_k127_7970256_14 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004058 321.0
PYH2_k127_7970256_15 PFAM peptidase S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001625 286.0
PYH2_k127_7970256_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000002049 244.0
PYH2_k127_7970256_17 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000002203 231.0
PYH2_k127_7970256_18 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000005841 215.0
PYH2_k127_7970256_19 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000001397 173.0
PYH2_k127_7970256_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.293e-253 793.0
PYH2_k127_7970256_20 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.000000000000000000000000000000000000000002988 158.0
PYH2_k127_7970256_21 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000001591 128.0
PYH2_k127_7970256_22 membrane K11622 - - 0.00000000000000000000007562 106.0
PYH2_k127_7970256_23 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000002218 98.0
PYH2_k127_7970256_24 - - - - 0.0000002986 61.0
PYH2_k127_7970256_25 Tetratricopeptide repeat protein - - - 0.0008761 50.0
PYH2_k127_7970256_3 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 2.458e-210 669.0
PYH2_k127_7970256_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007595 592.0
PYH2_k127_7970256_5 Peptidase M14, carboxypeptidase A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 561.0
PYH2_k127_7970256_6 Rhodopirellula transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008557 521.0
PYH2_k127_7970256_7 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 525.0
PYH2_k127_7970256_8 Pyrimidine nucleoside phosphorylase C-terminal domain K00756,K00758 GO:0003674,GO:0003824,GO:0004645,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009032,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0044424,GO:0044444,GO:0044464 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 481.0
PYH2_k127_7970256_9 Metalloenzyme superfamily K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 474.0
PYH2_k127_799656_0 Putative Flp pilus-assembly TadE/G-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 343.0
PYH2_k127_799656_1 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000006194 204.0
PYH2_k127_799656_2 succinate dehydrogenase - - - 0.000000000000000000000000003666 122.0
PYH2_k127_799656_3 transposition K07497 - - 0.000000000000000005292 86.0
PYH2_k127_799656_4 Carbohydrate esterase, sialic acid-specific acetylesterase - - - 0.00000000000111 75.0
PYH2_k127_799656_5 Belongs to the peptidase S10 family K09646 - - 0.0002948 47.0
PYH2_k127_8049780_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 4.329e-201 638.0
PYH2_k127_8049780_1 efflux transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 511.0
PYH2_k127_8049780_2 Putative esterase K07214 - - 0.00000000000000000000000000000000002171 141.0
PYH2_k127_8049780_3 inositol 2-dehydrogenase activity - - - 0.00000000000000000000000000000000004306 143.0
PYH2_k127_8049780_4 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000001121 124.0
PYH2_k127_8049780_6 nitric oxide dioxygenase activity - - - 0.0000000000000000000000003078 110.0
PYH2_k127_8049780_7 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000005991 83.0
PYH2_k127_8049780_8 Phosphoesterase family - - - 0.00000001572 58.0
PYH2_k127_8087909_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 379.0
PYH2_k127_8087909_1 alpha-L-rhamnosidase - - - 0.000000000000000000000000000000000000000000000000000000007258 208.0
PYH2_k127_8087909_2 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000000000000000004495 164.0
PYH2_k127_8087909_3 - - - - 0.00000000000000009558 87.0
PYH2_k127_8087909_4 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000001246 83.0
PYH2_k127_8087909_5 - - - - 0.0000000000005952 76.0
PYH2_k127_8099755_0 Belongs to the peptidase S8 family K12287 - - 0.0000000000000009355 92.0
PYH2_k127_8099755_1 Immune inhibitor A peptidase M6 - - - 0.00002838 53.0
PYH2_k127_8133528_0 PFAM regulatory protein LuxR - - - 0.0000000000000000000000000000000000000000000000000001383 193.0
PYH2_k127_8133528_1 helix_turn_helix, Lux Regulon K11618 - - 0.000000000000000000000000000007774 123.0
PYH2_k127_8133528_2 AAA domain K07133 - - 0.0000000000000000000000000007058 114.0
PYH2_k127_8133528_3 Histidine kinase - - - 0.000001612 50.0
PYH2_k127_8138301_0 Transposase (IS116 IS110 IS902 family) - - - 0.00000000000000000000005113 113.0
PYH2_k127_8138301_1 Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000001365 103.0
PYH2_k127_8156774_0 Binding-protein-dependent transport system inner membrane component K02025,K05814,K10118 - - 0.000000000000000000000000000000000000000000000000000000000003848 216.0
PYH2_k127_8156774_1 Bacterial extracellular solute-binding protein - - - 0.000000000000000000000000000000000000000000000000000001095 204.0
PYH2_k127_8169525_0 Melibiase K07407 - 3.2.1.22 3.081e-266 837.0
PYH2_k127_8169525_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 6.919e-205 649.0
PYH2_k127_8169525_11 Radical SAM superfamily - - - 0.000000000000003221 81.0
PYH2_k127_8169525_12 TIGRFAM conserved repeat domain protein - - - 0.0000000000001821 85.0
PYH2_k127_8169525_13 beta-galactosidase activity - - - 0.00001773 54.0
PYH2_k127_8169525_2 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 579.0
PYH2_k127_8169525_3 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 533.0
PYH2_k127_8169525_4 Malate/L-lactate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 347.0
PYH2_k127_8169525_6 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001519 220.0
PYH2_k127_8169525_7 - - - - 0.00000000000000000000000000000000000000000000000000000001114 203.0
PYH2_k127_8169525_8 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000004286 141.0
PYH2_k127_8169525_9 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000004228 119.0
PYH2_k127_8191442_0 Methyltransferase, chemotaxis proteins K00575,K13924 - 2.1.1.80,3.1.1.61 3.714e-250 819.0
PYH2_k127_8191442_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 567.0
PYH2_k127_8191442_10 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004948 252.0
PYH2_k127_8191442_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 529.0
PYH2_k127_8191442_3 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 499.0
PYH2_k127_8191442_4 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 512.0
PYH2_k127_8191442_5 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005917 471.0
PYH2_k127_8191442_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006583 416.0
PYH2_k127_8191442_7 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007264 376.0
PYH2_k127_8191442_8 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006354 378.0
PYH2_k127_8191442_9 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008942 339.0
PYH2_k127_8192714_0 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 305.0
PYH2_k127_8192714_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000009092 237.0
PYH2_k127_8192714_2 homoserine transmembrane transporter activity K06600,K06895 - - 0.00000000000000000000000000000000000000000000000000000000001083 213.0
PYH2_k127_8192714_3 pfam nipsnap - - - 0.000000000000000000000000000000000000000000000000004116 192.0
PYH2_k127_8192714_5 - - - - 0.00000000000001189 77.0
PYH2_k127_8192714_6 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000001875 70.0
PYH2_k127_8192714_7 Beta-lactamase superfamily domain - - - 0.0006191 46.0
PYH2_k127_8220980_0 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008445 576.0
PYH2_k127_8220980_1 Pyridoxal phosphate biosynthetic protein PdxA K22024 - 1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 438.0
PYH2_k127_8220980_2 thiolester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003308 298.0
PYH2_k127_8220980_3 kinase activity K22129 - 2.7.1.219,2.7.1.220 0.000000000000000000000000000000000000000000000000000000000000001251 234.0
PYH2_k127_8220980_4 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000000000000000000000000000000000000000000008083 201.0
PYH2_k127_8220980_5 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.000000000000000000000000000000003716 135.0
PYH2_k127_8256167_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1018.0
PYH2_k127_8256167_1 serine-type peptidase activity K01278 - 3.4.14.5 7.68e-305 949.0
PYH2_k127_8256167_2 Peptidase dimerisation domain K12941 - - 1.83e-227 715.0
PYH2_k127_8256167_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.173e-217 679.0
PYH2_k127_8256167_4 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001927 269.0
PYH2_k127_8256167_5 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000283 153.0
PYH2_k127_8256167_6 Hep Hag repeat protein - - - 0.00000000000000000000006201 115.0
PYH2_k127_8261442_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 7.012e-245 777.0
PYH2_k127_8261442_1 2Fe-2S -binding domain K13483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001161 258.0
PYH2_k127_8320800_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000004041 105.0
PYH2_k127_8329560_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.303e-305 951.0
PYH2_k127_8329560_1 beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 317.0
PYH2_k127_8329560_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000001656 165.0
PYH2_k127_8364058_0 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000000006017 209.0
PYH2_k127_8364058_1 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.0000000000000000000000000000000000000000000000002447 188.0
PYH2_k127_8364058_2 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000004663 51.0
PYH2_k127_8364058_3 component of anaerobic dehydrogenases - - - 0.00002731 51.0
PYH2_k127_8364058_4 Integrase core domain K07497 GO:0008150,GO:0009987,GO:0032196 - 0.00006735 46.0
PYH2_k127_8366389_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 4.088e-226 717.0
PYH2_k127_8366389_1 proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 576.0
PYH2_k127_8366389_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000679 348.0
PYH2_k127_8366389_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000401 124.0
PYH2_k127_8398730_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008648 587.0
PYH2_k127_8398730_1 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000001705 126.0
PYH2_k127_8398730_2 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000001275 68.0
PYH2_k127_8398730_3 DNA integration - - - 0.00000000003717 72.0
PYH2_k127_8398730_4 Carboxypeptidase regulatory-like domain - - - 0.00001018 53.0
PYH2_k127_8411382_0 DNA topoisomerase K02622 - - 2.19e-228 723.0
PYH2_k127_8411382_1 O-methyltransferase activity - GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 624.0
PYH2_k127_8411382_10 - - - - 0.00000000000000000000000000000626 126.0
PYH2_k127_8411382_11 Transcription factor zinc-finger K09981 - - 0.000000000005162 72.0
PYH2_k127_8411382_12 iron-sulfur cluster assembly - - - 0.0001156 51.0
PYH2_k127_8411382_13 Protein of unknown function (DUF1566) - - - 0.0006269 47.0
PYH2_k127_8411382_2 Belongs to the type II topoisomerase GyrA ParC subunit family K02621 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 572.0
PYH2_k127_8411382_3 Aldo/keto reductase family K00002 - 1.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 527.0
PYH2_k127_8411382_4 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 507.0
PYH2_k127_8411382_5 dehydrogenases and related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 402.0
PYH2_k127_8411382_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 350.0
PYH2_k127_8411382_7 arylsulfatase activity K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 344.0
PYH2_k127_8411382_8 Methyltransferase type 12 K03439 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0016278,GO:0016740,GO:0016741,GO:0032259 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 347.0
PYH2_k127_8411382_9 Belongs to the 5'-nucleotidase family K01081,K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000002266 222.0
PYH2_k127_8411703_0 Carboxypeptidase regulatory-like domain - - - 5.003e-292 934.0
PYH2_k127_8411703_1 heat shock protein binding - - - 1.608e-276 875.0
PYH2_k127_8411703_10 DinB superfamily - - - 0.0000000000000000000000000009809 119.0
PYH2_k127_8411703_11 PFAM PilT protein domain protein - - - 0.0000000000000000000000001747 112.0
PYH2_k127_8411703_12 PFAM Integral membrane protein TerC K05794 - - 0.00000000000000003206 83.0
PYH2_k127_8411703_13 - - - - 0.0000000000003594 73.0
PYH2_k127_8411703_15 HicB family - - - 0.000004923 53.0
PYH2_k127_8411703_3 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002606 431.0
PYH2_k127_8411703_4 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 406.0
PYH2_k127_8411703_5 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 293.0
PYH2_k127_8411703_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005032 295.0
PYH2_k127_8411703_7 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002157 271.0
PYH2_k127_8411703_8 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000001128 262.0
PYH2_k127_8413173_1 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003331 256.0
PYH2_k127_8413173_2 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000002278 148.0
PYH2_k127_8413173_3 - - - - 0.0000005079 55.0
PYH2_k127_8414174_0 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000005782 112.0
PYH2_k127_8414174_1 Serine threonine protein kinase - - - 0.000000000000000000001763 110.0
PYH2_k127_8419082_0 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 431.0
PYH2_k127_8419082_1 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 330.0
PYH2_k127_8419082_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001254 274.0
PYH2_k127_8419082_3 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000003162 145.0
PYH2_k127_8437779_0 Glycosyl transferase, family 2 K00721,K07011,K12990,K14597,K16555,K21349 - 2.4.1.268,2.4.1.83 0.000000000000000000000000000000000000000000000000000000001186 215.0
PYH2_k127_8437779_1 radical SAM domain protein - - - 0.000000000005351 79.0
PYH2_k127_8437779_2 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000001946 57.0
PYH2_k127_8438570_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 3.614e-267 838.0
PYH2_k127_8438570_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 544.0
PYH2_k127_8438570_2 sulfate adenylyltransferase (ATP) activity K00955,K00956 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 398.0
PYH2_k127_8438570_3 Phosphoadenosine phosphosulfate reductase family K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 384.0
PYH2_k127_8466593_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000036 256.0
PYH2_k127_8466593_1 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000000000000000000000000000000002373 226.0
PYH2_k127_8466593_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000002624 209.0
PYH2_k127_8466593_3 MerR HTH family regulatory protein K13640 - - 0.0000000000000000000000000000000000258 138.0
PYH2_k127_8466593_4 MlaD protein K02067 - - 0.0000000000000000000000000000000001658 141.0
PYH2_k127_8466593_5 - - - - 0.0000000000000000000000000000007519 134.0
PYH2_k127_8466593_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000002603 87.0
PYH2_k127_8466593_7 Domain of unknown function (DUF4115) K15539 - - 0.00000000006224 73.0
PYH2_k127_8466593_8 outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000002231 64.0
PYH2_k127_8466593_9 - - - - 0.0003521 45.0
PYH2_k127_8484224_0 - - - - 0.0000000000000000000000000000000000000002905 154.0
PYH2_k127_8484224_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008760,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016740,GO:0016765,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.5.1.7 0.000000000000000000000000000000001293 151.0
PYH2_k127_8484224_3 Radical SAM superfamily - - - 0.00000000007424 76.0
PYH2_k127_8493593_0 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 503.0
PYH2_k127_8493593_1 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001135 273.0
PYH2_k127_8493593_2 transposition K07497 - - 0.000000000000000001199 93.0
PYH2_k127_8510321_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.638e-207 656.0
PYH2_k127_8510321_1 Gamma-glutamyltranspeptidase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 587.0
PYH2_k127_8510321_10 von Willebrand factor, type A - - - 0.0000000000000002752 83.0
PYH2_k127_8510321_11 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000002981 70.0
PYH2_k127_8510321_12 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.000000005478 61.0
PYH2_k127_8510321_2 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 539.0
PYH2_k127_8510321_3 histidine kinase A domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 387.0
PYH2_k127_8510321_4 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784,K12448 - 5.1.3.2,5.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 361.0
PYH2_k127_8510321_5 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009434 301.0
PYH2_k127_8510321_6 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005706 250.0
PYH2_k127_8510321_7 2Fe-2S -binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000115 190.0
PYH2_k127_8510321_8 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000006355 162.0
PYH2_k127_8510321_9 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000006625 113.0
PYH2_k127_8511592_0 domain, Protein K20276 - - 2.477e-220 695.0
PYH2_k127_8511592_1 Protein of unknown function (DUF1501) - - - 3.108e-212 670.0
PYH2_k127_8511592_2 anaphase-promoting complex binding - - - 5.036e-211 681.0
PYH2_k127_8511592_3 IgA Peptidase M64 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 402.0
PYH2_k127_8511592_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000001274 229.0
PYH2_k127_8511592_5 Histidine kinase K02480 - 2.7.13.3 0.000000000000000001541 101.0
PYH2_k127_8511592_6 Integrase - - - 0.000000000006612 71.0
PYH2_k127_8511592_7 Hydrolyzes a variety of simple alpha-D-galactoside as well as more complex molecules such as oligosaccharides and polysaccharides K07407 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004557,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015925,GO:0016052,GO:0016787,GO:0016798,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0070085,GO:0071554,GO:0071704,GO:1901575 3.2.1.22 0.0002003 45.0
PYH2_k127_8511592_8 Integrase - - - 0.0003874 48.0
PYH2_k127_85155_0 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000598 352.0
PYH2_k127_85155_1 Xylose isomerase-like TIM barrel K03335 - 4.2.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 347.0
PYH2_k127_85155_2 metallopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000001517 228.0
PYH2_k127_85155_3 - - - - 0.000000000000000000000000000001147 127.0
PYH2_k127_85155_4 Belongs to the ompA family - - - 0.0000000000000000000000001296 108.0
PYH2_k127_8519413_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1126.0
PYH2_k127_8519413_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 535.0
PYH2_k127_8519413_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 415.0
PYH2_k127_8519413_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 340.0
PYH2_k127_8526776_0 phosphorelay signal transduction system - - - 1.17e-208 657.0
PYH2_k127_8526776_1 COG3119 Arylsulfatase A and related enzymes K01134 - 3.1.6.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 614.0
PYH2_k127_8526776_10 BNR repeat-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004222 358.0
PYH2_k127_8526776_11 exo-alpha-(2->6)-sialidase activity K01186 - 3.2.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 353.0
PYH2_k127_8526776_12 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 316.0
PYH2_k127_8526776_13 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 309.0
PYH2_k127_8526776_14 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000000000000000000000000000000000000000000000000000000000000000001122 245.0
PYH2_k127_8526776_15 - - - - 0.00000000000000000000000000000000000000000000000000000000001011 222.0
PYH2_k127_8526776_16 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000004833 193.0
PYH2_k127_8526776_17 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000002647 151.0
PYH2_k127_8526776_18 Sulfate permease family K03321 - - 0.00000000000000000000000000000003338 129.0
PYH2_k127_8526776_19 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000006304 121.0
PYH2_k127_8526776_2 phosphorelay sensor kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001463 600.0
PYH2_k127_8526776_20 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07636 - 2.7.13.3 0.0000000000000000000832 103.0
PYH2_k127_8526776_21 phosphorelay signal transduction system - - - 0.0000000000002507 76.0
PYH2_k127_8526776_22 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.000001084 61.0
PYH2_k127_8526776_23 Tetratricopeptide repeats K12132 - 2.7.11.1 0.0001544 55.0
PYH2_k127_8526776_24 SpoVT / AbrB like domain K07172 - - 0.0009521 49.0
PYH2_k127_8526776_3 PFAM peptidase U62 modulator of DNA gyrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 514.0
PYH2_k127_8526776_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 472.0
PYH2_k127_8526776_5 stress-induced mitochondrial fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 467.0
PYH2_k127_8526776_6 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 467.0
PYH2_k127_8526776_7 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004588 454.0
PYH2_k127_8526776_8 Histidine kinase HAMP K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001696 451.0
PYH2_k127_8526776_9 PFAM formate nitrite transporter K06212,K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004429 363.0
PYH2_k127_8531815_0 Glycosyl transferases group 1 - - - 1.057e-320 1005.0
PYH2_k127_8531815_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 483.0
PYH2_k127_8531815_2 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 344.0
PYH2_k127_8531815_3 PFAM flagellin domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005806 283.0
PYH2_k127_8531815_4 cheY-homologous receiver domain K03413 - - 0.000000000000000000000000000000000000000000000000000000000000009896 220.0
PYH2_k127_8531815_5 PFAM flagellar FlbT family protein K06601 - - 0.000000000000000000000000000000000000000000008486 166.0
PYH2_k127_8531815_6 PFAM flagellar FlaF family protein K06602 - - 0.00000000000000000000000000000000005734 138.0
PYH2_k127_8531815_7 PFAM Metal-dependent hydrolase HDOD - - - 0.000008332 52.0
PYH2_k127_8543527_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 291.0
PYH2_k127_8543527_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000007049 189.0
PYH2_k127_8543527_2 - - - - 0.0000000000000000000000000000000000000000000000004227 188.0
PYH2_k127_8543527_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.0000000000000000000000000000000004242 134.0
PYH2_k127_8543527_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000003285 112.0
PYH2_k127_8553371_0 FAD dependent oxidoreductase K06954 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 374.0
PYH2_k127_8553371_1 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009805 314.0
PYH2_k127_8553371_2 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000004487 258.0
PYH2_k127_8558380_0 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000003206 208.0
PYH2_k127_8558380_1 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000003356 184.0
PYH2_k127_8558380_2 response to heat - - - 0.00000000000003661 76.0
PYH2_k127_8567870_0 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000000000000000000005073 169.0
PYH2_k127_8567870_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000000000000868 86.0
PYH2_k127_8567870_2 nuclear chromosome segregation - - - 0.0009021 50.0
PYH2_k127_8567883_0 Peptidase family S58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 441.0
PYH2_k127_8567883_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000005943 270.0
PYH2_k127_8579450_0 Carboxypeptidase regulatory-like domain - - - 6.155e-205 657.0
PYH2_k127_8579450_1 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003667 453.0
PYH2_k127_8579450_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 427.0
PYH2_k127_8594368_0 Sigma-70, region 4 K03088 - - 0.00000000000000000000000005545 115.0
PYH2_k127_8594368_2 transposition K07497 - - 0.00003024 47.0
PYH2_k127_861585_0 Belongs to the enoyl-CoA hydratase isomerase family K07516 - 1.1.1.35 3.125e-204 657.0
PYH2_k127_861585_1 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000005152 167.0
PYH2_k127_861585_2 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000000000001487 166.0
PYH2_k127_861585_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000003387 134.0
PYH2_k127_861585_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000005515 136.0
PYH2_k127_861585_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000008589 132.0
PYH2_k127_861585_6 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000008043 106.0
PYH2_k127_8629166_0 efflux transmembrane transporter activity - - - 2.885e-205 665.0
PYH2_k127_8629166_1 Integrase core domain - - - 0.00000000000000000000001601 106.0
PYH2_k127_8629166_2 COG1943 Transposase and inactivated derivatives - - - 0.000000000000000008231 84.0
PYH2_k127_8629294_0 serine-type peptidase activity - - - 0.0 1077.0
PYH2_k127_8629294_1 Right handed beta helix region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 469.0
PYH2_k127_8629294_2 PEGA domain - - - 0.000000000000000000000000000001273 126.0
PYH2_k127_8629294_3 Histidine kinase - - - 0.0000000000000000000213 92.0
PYH2_k127_8635309_0 - - - - 0.000000000000000000000000000005462 138.0
PYH2_k127_8635309_1 ubiE/COQ5 methyltransferase family - - - 0.000003005 54.0
PYH2_k127_86477_0 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003449 602.0
PYH2_k127_86477_1 belongs to the lyase 1 family. Argininosuccinate lyase subfamily K01755,K14681 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 461.0
PYH2_k127_86477_2 response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 443.0
PYH2_k127_86477_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003267 257.0
PYH2_k127_86477_4 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000002842 226.0
PYH2_k127_86477_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000339 140.0
PYH2_k127_8659232_0 COG0493 NADPH-dependent glutamate synthase beta chain and K00266 - 1.4.1.13,1.4.1.14 1.531e-248 795.0
PYH2_k127_8659232_1 glutamate synthase - - - 0.0000000000000000000000000000002836 133.0
PYH2_k127_8659232_2 Zn_pept - - - 0.000000000000000000000001393 110.0
PYH2_k127_8659232_3 PFAM PEBP family protein K06910 - - 0.000000000000004139 81.0
PYH2_k127_8661522_0 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 462.0
PYH2_k127_8661522_1 TIGRFAM phosphoesterase, MJ0936 family - - - 0.000000000000000000000000000000000000000000000005112 180.0
PYH2_k127_8661522_2 L-fucose isomerase and related - - - 0.00000000000000000000003749 115.0
PYH2_k127_8665912_0 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000086 186.0
PYH2_k127_8665912_1 Transposase K07497 - - 0.00000000000000000000000000000000002203 136.0
PYH2_k127_8665912_2 Psort location CytoplasmicMembrane, score - - - 0.00000000000000000000000000002419 135.0
PYH2_k127_8665912_3 HsdM N-terminal domain - - - 0.0000000000000000000000002071 108.0
PYH2_k127_8665912_4 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000093 105.0
PYH2_k127_8665912_5 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000003934 99.0
PYH2_k127_8665912_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000002181 80.0
PYH2_k127_8665912_7 Plasmid pRiA4b ORF-3-like protein - - - 0.0000000000003951 71.0
PYH2_k127_8678185_0 iron dependent repressor - - - 0.000000000000000000301 96.0
PYH2_k127_8685235_0 Catalyzes the interconversion of ornithine to glutamate semialdehyde K00819 - 2.6.1.13 3.787e-202 634.0
PYH2_k127_8685235_1 2-dehydropantoate 2-reductase activity K00077,K04940 - 1.1.1.169,1.5.1.28 6.065e-195 612.0
PYH2_k127_8685235_10 helix_turn_helix ASNC type K03718 - - 0.000000000000000000000000000000003566 134.0
PYH2_k127_8685235_11 peroxiredoxin activity K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016020,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0071944,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000003181 70.0
PYH2_k127_8685235_12 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000000004478 63.0
PYH2_k127_8685235_13 helix_turn_helix ASNC type K03718 - - 0.00085 45.0
PYH2_k127_8685235_2 PFAM ABC transporter related K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 359.0
PYH2_k127_8685235_3 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 348.0
PYH2_k127_8685235_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567,K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003056 327.0
PYH2_k127_8685235_6 Binding-protein-dependent transport system inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004426 281.0
PYH2_k127_8685235_7 amino acid ABC transporter K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002179 271.0
PYH2_k127_8685235_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000392 160.0
PYH2_k127_8685235_9 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.000000000000000000000000000000000003847 139.0
PYH2_k127_8703962_0 SNF2 family N-terminal domain - - - 2.5e-323 1024.0
PYH2_k127_8703962_1 Peptidase family M28 - - - 1.083e-213 677.0
PYH2_k127_8703962_2 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 471.0
PYH2_k127_8703962_3 TIGRFAM glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 323.0
PYH2_k127_8703962_4 SMART phospholipase D Transphosphatidylase - - - 0.00000000000000000000000004364 121.0
PYH2_k127_8703962_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000138 74.0
PYH2_k127_8703962_6 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.00000002019 59.0
PYH2_k127_8705097_0 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000699 584.0
PYH2_k127_8705097_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 521.0
PYH2_k127_8705097_10 Bacterial Ig-like domain (group 1) - - - 0.0000000000000000000000000000000001024 142.0
PYH2_k127_8705097_11 Parallel beta-helix repeats - - - 0.000000000000000000000000000000002726 150.0
PYH2_k127_8705097_12 Tetratricopeptide repeat - - - 0.00000000000000000000000000000005118 134.0
PYH2_k127_8705097_13 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000009013 79.0
PYH2_k127_8705097_14 myo-inosose-2 dehydratase activity - - - 0.0000002827 53.0
PYH2_k127_8705097_2 Receptor K02014,K16087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 519.0
PYH2_k127_8705097_3 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 476.0
PYH2_k127_8705097_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007271 340.0
PYH2_k127_8705097_5 4Fe-4S binding domain K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004441 332.0
PYH2_k127_8705097_6 LytTr DNA-binding domain K02477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 310.0
PYH2_k127_8705097_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001223 286.0
PYH2_k127_8705097_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001322 273.0
PYH2_k127_8705097_9 membrane - - - 0.000000000000000000000000000000000000000000002316 172.0
PYH2_k127_8741009_0 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 1.23e-274 853.0
PYH2_k127_8741009_1 Aldehyde dehydrogenase family K22187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 535.0
PYH2_k127_8741009_10 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000008983 88.0
PYH2_k127_8741009_11 Integral membrane protein - - - 0.00000003844 55.0
PYH2_k127_8741009_12 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00005834 50.0
PYH2_k127_8741009_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 505.0
PYH2_k127_8741009_3 type VI secretion protein K11900,K11901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 407.0
PYH2_k127_8741009_4 Fumarylacetoacetate (FAA) hydrolase K14259 - 4.2.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 306.0
PYH2_k127_8741009_5 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007627 259.0
PYH2_k127_8741009_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000002712 213.0
PYH2_k127_8741009_7 PFAM cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000001091 183.0
PYH2_k127_8741009_9 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000198 164.0
PYH2_k127_8745400_0 Domain of unknown function (DUF4832) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 589.0
PYH2_k127_8745400_1 isomerase activity - - - 0.0000000000000000000007959 101.0
PYH2_k127_8745400_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000001724 94.0
PYH2_k127_8745400_3 PFAM PAAR motif - - - 0.00000000002077 66.0
PYH2_k127_8745400_4 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000004847 57.0
PYH2_k127_8745506_0 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 614.0
PYH2_k127_8745506_1 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 466.0
PYH2_k127_8745506_10 COG1629 Outer membrane receptor proteins, mostly Fe transport - - - 0.0000808 57.0
PYH2_k127_8745506_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 452.0
PYH2_k127_8745506_3 Succinylglutamate desuccinylase / Aspartoacylase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 421.0
PYH2_k127_8745506_4 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 381.0
PYH2_k127_8745506_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 340.0
PYH2_k127_8745506_6 PFAM Succinylglutamate desuccinylase Aspartoacylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005187 278.0
PYH2_k127_8745506_7 Mur ligase middle domain K01925,K01932 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000001074 207.0
PYH2_k127_8745506_8 - - - - 0.000000000000000000000000000002802 127.0
PYH2_k127_8745506_9 NUDIX domain K03575 - - 0.00000006879 60.0
PYH2_k127_8749420_0 Putative restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000005508 207.0
PYH2_k127_8749420_1 Putative restriction endonuclease - - - 0.00000000000007684 73.0
PYH2_k127_8749420_2 Uncharacterised protein family (UPF0175) - - - 0.00000000001573 72.0
PYH2_k127_8749420_3 Domain of unknown function (DUF3368) K07066 - - 0.00000000007689 69.0
PYH2_k127_8755981_0 L-lactate permease K03303 - - 9.092e-202 641.0
PYH2_k127_8755981_1 4-phosphoerythronate dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 295.0
PYH2_k127_8755981_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000009018 146.0
PYH2_k127_8755981_3 S53 subtilisin kexin sedolisin - - - 0.0005076 46.0
PYH2_k127_87629_0 Peptidase family M1 domain K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 395.0
PYH2_k127_87629_1 Aldo Keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001804 261.0
PYH2_k127_8764691_0 Domain in cystathionine beta-synthase and other proteins. - - - 3.164e-201 663.0
PYH2_k127_8764691_1 Carbamoyltransferase C-terminus K00612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 611.0
PYH2_k127_8764691_10 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000000000001564 185.0
PYH2_k127_8764691_11 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000002017 129.0
PYH2_k127_8764691_12 von Willebrand factor, type A - - - 0.00000000000000000000000000002147 131.0
PYH2_k127_8764691_13 COGs COG4299 conserved - - - 0.0000000000000000847 84.0
PYH2_k127_8764691_14 Fumarylacetoacetate hydrolase domain-containing protein - - - 0.00000000000222 70.0
PYH2_k127_8764691_15 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000002842 63.0
PYH2_k127_8764691_16 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000002118 58.0
PYH2_k127_8764691_2 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 569.0
PYH2_k127_8764691_3 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 520.0
PYH2_k127_8764691_4 Mur ligase middle domain K02558 - 6.3.2.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 458.0
PYH2_k127_8764691_5 Sodium:alanine symporter family K03310 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 439.0
PYH2_k127_8764691_6 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 376.0
PYH2_k127_8764691_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006953 253.0
PYH2_k127_8764691_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000009923 223.0
PYH2_k127_8764691_9 Cytidylate kinase-like family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000003094 214.0
PYH2_k127_8767537_0 COG3335 Transposase and inactivated derivatives K07494 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006535 549.0
PYH2_k127_8767537_1 Belongs to the protein-tyrosine phosphatase family. Non-receptor class myotubularin subfamily - - - 0.00004694 49.0
PYH2_k127_8798650_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1143.0
PYH2_k127_8798650_1 PFAM oxidoreductase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 306.0
PYH2_k127_8798650_2 Histidine kinase - - - 0.000000000000000000000000000000000000001798 156.0
PYH2_k127_8813576_0 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004962 583.0
PYH2_k127_8813576_1 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 306.0
PYH2_k127_8813576_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000001172 141.0
PYH2_k127_8813576_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000001618 68.0
PYH2_k127_8830948_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 453.0
PYH2_k127_8830948_1 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 379.0
PYH2_k127_8830948_2 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 347.0
PYH2_k127_8830948_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003586 247.0
PYH2_k127_8830948_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000003439 188.0
PYH2_k127_8830948_5 Transglutaminase/protease-like homologues - - - 0.000000000000000000001196 107.0
PYH2_k127_8837858_0 Protein of unknown function (DUF1579) - - - 0.00001029 55.0
PYH2_k127_8837858_1 - - - - 0.000946 44.0
PYH2_k127_8842498_0 Major Facilitator Superfamily - - - 9.064e-204 640.0
PYH2_k127_8842498_1 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 338.0
PYH2_k127_8842498_2 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.0000000000000000000000000000000000000003238 155.0
PYH2_k127_885722_0 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 589.0
PYH2_k127_885722_1 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002908 255.0
PYH2_k127_885722_2 ECF sigma factor - - - 0.0000000000000000000000000000000000000000000000000000000006313 208.0
PYH2_k127_885722_3 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000004986 185.0
PYH2_k127_8869005_0 PFAM transposase, IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005858 515.0
PYH2_k127_8871565_1 hmm pf01973 - - - 0.0000000261 64.0
PYH2_k127_8874336_0 hmm pf01609 - - - 0.000000000000000000000000000000000000000000009156 179.0
PYH2_k127_8888576_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 404.0
PYH2_k127_8888576_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000007342 234.0
PYH2_k127_8888576_2 outer membrane efflux protein - - - 0.00000006891 64.0
PYH2_k127_8888576_3 Prokaryotic N-terminal methylation motif K02679 - - 0.0004055 49.0
PYH2_k127_8893011_0 PFAM Integrase core domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 469.0
PYH2_k127_8893011_1 IstB-like ATP binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002484 273.0
PYH2_k127_8904301_0 Berberine and berberine like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002533 562.0
PYH2_k127_8904301_1 Belongs to the dihydrofolate reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 372.0
PYH2_k127_8904301_2 Domain of Unknown Function (DUF1259) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 340.0
PYH2_k127_8904301_3 PFAM 3-demethylubiquinone-9 K04750 - - 0.000000000000000000000000000000000000000000000000000000000000000009994 227.0
PYH2_k127_8904301_4 PFAM Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000001003 135.0
PYH2_k127_8904301_5 Universal stress protein family - - - 0.000000000000000000000005645 106.0
PYH2_k127_8929383_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 513.0
PYH2_k127_8929383_1 undecaprenyl-phosphate glucose phosphotransferase activity K03606,K07011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 449.0
PYH2_k127_8929383_2 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004467 429.0
PYH2_k127_8929383_3 Glycosyl transferase family group 2 - - - 0.0000000000000000000000000000000000000000000000000000000000008937 222.0
PYH2_k127_8929383_4 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000183 191.0
PYH2_k127_8929383_5 23S rRNA-intervening sequence protein - - - 0.0000000000000699 71.0
PYH2_k127_8961243_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 0.0 1185.0
PYH2_k127_8961243_1 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005312 270.0
PYH2_k127_8961243_2 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.000000000000000000255 90.0
PYH2_k127_8968971_0 Filamentation induced by cAMP protein fic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 415.0
PYH2_k127_8968971_1 Uncharacterized protein conserved in bacteria (DUF2130) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001383 289.0
PYH2_k127_8968971_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.0000000002232 65.0
PYH2_k127_8968971_13 - - - - 0.000004319 50.0
PYH2_k127_8968971_14 ORF6N domain - - - 0.00004626 46.0
PYH2_k127_8968971_15 - - - - 0.0002688 48.0
PYH2_k127_8968971_16 Addiction module antitoxin, RelB DinJ family K07075 - - 0.0005623 44.0
PYH2_k127_8968971_2 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000000000000000000000000000000000000000000000006689 215.0
PYH2_k127_8968971_3 DNA topoisomerase type IA zn finger domain protein K07448 - - 0.000000000000000000000000000000000000000000000000002993 191.0
PYH2_k127_8968971_4 Helix-turn-helix domain - - - 0.00000000000000000000000000000002158 129.0
PYH2_k127_8968971_5 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000001743 102.0
PYH2_k127_8968971_6 - - - - 0.00000000000000000000001817 108.0
PYH2_k127_8968971_7 Helix-turn-helix domain - - - 0.0000000000000000000001015 100.0
PYH2_k127_8968971_8 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000003485 97.0
PYH2_k127_8968971_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000002448 89.0
PYH2_k127_8973591_2 - - - - 0.000000009937 65.0
PYH2_k127_9000489_0 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000005164 248.0
PYH2_k127_9000489_1 PFAM transposase IS4 family protein - - - 0.0000000000000000000000000000000000000000000000000002963 202.0
PYH2_k127_9000489_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000028 63.0
PYH2_k127_9010848_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 421.0
PYH2_k127_9010848_1 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 306.0
PYH2_k127_9010848_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000000000008034 123.0
PYH2_k127_9018137_0 TIGRFAM ATPase, FliI YscN family K02412,K03224 - 3.6.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001992 537.0
PYH2_k127_9018137_1 PFAM sigma-54 factor interaction domain-containing protein K10943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 422.0
PYH2_k127_9018137_10 Flagellar basal body rod modification protein K02389 GO:0001539,GO:0005575,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009424,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0071978,GO:0097588 - 0.0000000000001835 74.0
PYH2_k127_9018137_11 Flagellar biosynthesis K02411 - - 0.000000006453 66.0
PYH2_k127_9018137_12 bacterial-type flagellum organization K02413 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000001903 55.0
PYH2_k127_9018137_13 bacterial-type flagellum assembly K02414 - - 0.00002366 58.0
PYH2_k127_9018137_2 flagellar motor switch protein FliG K02410 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 372.0
PYH2_k127_9018137_3 The M ring may be actively involved in energy transduction K02409 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001073 294.0
PYH2_k127_9018137_4 Flagella basal body rod protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002442 282.0
PYH2_k127_9018137_5 phosphorelay sensor kinase activity K07708,K07710,K10942 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000006276 228.0
PYH2_k127_9018137_6 flagellar basal-body rod protein FlgC K02388 - - 0.000000000000000000000000000000000000001192 151.0
PYH2_k127_9018137_7 two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000001502 118.0
PYH2_k127_9018137_8 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000456 93.0
PYH2_k127_9018137_9 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000551 89.0
PYH2_k127_903439_0 PBS lyase HEAT-like repeat - - - 0.0000000000000000000000002044 121.0
PYH2_k127_903439_1 - - - - 0.0000007588 51.0
PYH2_k127_9037527_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 487.0
PYH2_k127_9037527_1 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 374.0
PYH2_k127_9037527_10 Transcriptional regulator K07979 - - 0.0000000000000000003408 91.0
PYH2_k127_9037527_11 Bacterial Ig-like domain (group 3) K01179 - 3.2.1.4 0.00000001611 64.0
PYH2_k127_9037527_12 TIGRFAM PEP-CTERM system TPR-repeat lipoprotein - - - 0.000002119 60.0
PYH2_k127_9037527_2 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 349.0
PYH2_k127_9037527_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008084 252.0
PYH2_k127_9037527_4 esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000348 235.0
PYH2_k127_9037527_5 Creatinine amidohydrolase - - - 0.0000000000000000000000000000000000000005237 159.0
PYH2_k127_9037527_6 - - - - 0.000000000000000000000000000000001273 141.0
PYH2_k127_9037527_7 Membrane - - - 0.000000000000000000000000000001737 134.0
PYH2_k127_9037527_8 nuclear chromosome segregation K02004 - - 0.000000000000000000000002643 121.0
PYH2_k127_9037527_9 Cytochrome b/b6/petB K00127 - - 0.00000000000000000000002179 110.0
PYH2_k127_9053611_0 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000000004241 131.0
PYH2_k127_9053611_1 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000004803 112.0
PYH2_k127_9053611_2 Integrase core domain - - - 0.00000000000001796 81.0
PYH2_k127_9053611_3 Integrase core domain - - - 0.000000000009319 66.0
PYH2_k127_9053611_4 Integrase - - - 0.000000004025 60.0
PYH2_k127_9091631_0 TonB-dependent Receptor Plug Domain - - - 1.871e-254 823.0
PYH2_k127_9091631_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 601.0
PYH2_k127_9091631_2 Psort location Cytoplasmic, score 9.97 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 350.0
PYH2_k127_9091631_3 Sulfatase K01133 - 3.1.6.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 344.0
PYH2_k127_9091631_4 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000008627 117.0
PYH2_k127_9097557_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1129.0
PYH2_k127_9097557_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 4.357e-232 730.0
PYH2_k127_9097557_2 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 409.0
PYH2_k127_9097557_3 Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002622 281.0
PYH2_k127_9097557_4 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000005557 195.0
PYH2_k127_9097557_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000002728 98.0
PYH2_k127_9097557_6 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.00000000000000000001063 93.0
PYH2_k127_9097557_7 PFAM Formiminotransferase-cyclodeaminase - - - 0.0000000000000000002042 95.0
PYH2_k127_9119529_0 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000006729 180.0
PYH2_k127_9119529_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000002785 100.0
PYH2_k127_9119529_2 Leucine-rich repeats, outliers - - - 0.0000001367 62.0
PYH2_k127_9135762_0 PFAM Beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 527.0
PYH2_k127_9135762_1 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000008169 237.0
PYH2_k127_9135762_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000001557 75.0
PYH2_k127_9135949_0 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002194 261.0
PYH2_k127_9135949_1 Putative peptidoglycan binding domain - - - 0.00000000000000000000000000000000000000000000002459 178.0
PYH2_k127_9135949_2 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000001491 148.0
PYH2_k127_9135949_3 COGs COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.000000000000000000000000000002522 126.0
PYH2_k127_9135949_4 Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide - - - 0.0002798 43.0
PYH2_k127_9170457_0 Belongs to the DegT DnrJ EryC1 family K19715 - 2.6.1.109 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 401.0
PYH2_k127_9170457_1 ASPIC and UnbV - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 350.0
PYH2_k127_9170457_2 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.0000000000000000000000000004343 119.0
PYH2_k127_9170457_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000008817 109.0
PYH2_k127_9170457_4 SPTR CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000000001105 109.0
PYH2_k127_9170457_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000002415 105.0
PYH2_k127_9174101_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 422.0
PYH2_k127_9174101_1 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000000001168 198.0
PYH2_k127_9174101_2 TIGRFAM TRAP transporter, DctM subunit - - - 0.000000000007962 67.0
PYH2_k127_9177844_0 - - - - 0.0000000000000000000000000000000000000000000000001666 181.0
PYH2_k127_9177844_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000009099 98.0
PYH2_k127_9182935_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001443 275.0
PYH2_k127_9182935_1 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000005537 229.0
PYH2_k127_9182935_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000001779 202.0
PYH2_k127_9182935_3 helix_turn_helix, Lux Regulon - - - 0.00000000134 61.0
PYH2_k127_9215026_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.000000000000000000000000000000000000000002055 163.0
PYH2_k127_9215026_1 membrane-fusion protein - - - 0.000000000000000000000000000004639 135.0
PYH2_k127_9215026_2 HlyD membrane-fusion protein of T1SS - - - 0.00000000000000000000000004585 122.0
PYH2_k127_9215026_3 HlyD membrane-fusion protein of T1SS - - - 0.00000000000000000000002145 113.0
PYH2_k127_9215026_4 HEAT repeat-containing protein - - - 0.000003388 55.0
PYH2_k127_9230099_0 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002312 472.0
PYH2_k127_9230099_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003791 357.0
PYH2_k127_9230099_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 289.0
PYH2_k127_9238087_0 PFAM Sodium calcium exchanger membrane region K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 487.0
PYH2_k127_9238087_1 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005405 381.0
PYH2_k127_9238087_2 Uroporphyrinogen decarboxylase (URO-D) K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 292.0
PYH2_k127_9238087_3 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001016 229.0
PYH2_k127_9238087_4 Domain of unknown function (DUF5107) - - - 0.000000000000000000000000000000000000000000000000000009494 214.0
PYH2_k127_9238087_5 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000003784 181.0
PYH2_k127_9238087_6 methyltransferase - - - 0.000000000000000000000000000000001143 151.0
PYH2_k127_9238087_7 - - - - 0.000000000000000000000002026 109.0
PYH2_k127_9238087_8 Glycosyltransferase like family 2 - - - 0.000000000000000000002427 110.0
PYH2_k127_9238087_9 Methyltransferase domain - - - 0.00004009 57.0
PYH2_k127_924036_0 3-beta hydroxysteroid dehydrogenase/isomerase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 451.0
PYH2_k127_924036_1 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 374.0
PYH2_k127_924036_2 PFAM glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001387 272.0
PYH2_k127_924036_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003136 241.0
PYH2_k127_924036_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.00001551 48.0
PYH2_k127_9286475_1 amino acid - - - 0.0003133 43.0
PYH2_k127_9291584_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000758 564.0
PYH2_k127_9291584_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 325.0
PYH2_k127_9291584_2 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000004346 228.0
PYH2_k127_9291584_3 cheY-homologous receiver domain K11443 - - 0.0000000000000000000000000000000000000000000000813 172.0
PYH2_k127_9291584_4 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.00000000000000000000000000000000000000008544 161.0
PYH2_k127_9305617_0 response to heat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001532 280.0
PYH2_k127_9305617_1 Dodecin K09165 - - 0.00000000000000000000906 93.0
PYH2_k127_9305617_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000007453 74.0
PYH2_k127_9305617_3 Sigma-70, region 4 K03088 - - 0.000000002609 59.0
PYH2_k127_9320069_0 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 2.337e-206 650.0
PYH2_k127_9320069_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 338.0
PYH2_k127_9320069_2 Domain of unknown function (DUF362) - - - 0.0000000007609 63.0
PYH2_k127_935969_0 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 538.0
PYH2_k127_935969_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000003227 223.0
PYH2_k127_935969_2 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000008978 216.0
PYH2_k127_935969_3 response to heat - - - 0.0000000000000381 76.0
PYH2_k127_94009_0 PFAM Glycoside hydrolase 15-related - - - 3.784e-258 822.0
PYH2_k127_94009_1 PFAM Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005734 486.0
PYH2_k127_943822_0 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 538.0
PYH2_k127_943822_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008342 526.0
PYH2_k127_943822_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009526 469.0
PYH2_k127_943822_3 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 418.0
PYH2_k127_943822_4 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 388.0
PYH2_k127_943822_5 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005015 284.0
PYH2_k127_943822_6 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000003748 226.0
PYH2_k127_943822_7 Methyltransferase type 11 - - - 0.0000000000000000000000000000001366 135.0
PYH2_k127_94631_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1151.0
PYH2_k127_94631_1 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1041.0
PYH2_k127_94631_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 607.0
PYH2_k127_94631_3 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 472.0
PYH2_k127_94631_4 Xylose isomerase-like TIM barrel K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 398.0
PYH2_k127_94631_5 Belongs to the ParA family K04562 - - 0.0000000000000000000000000000000000000000000000000000000000008603 221.0
PYH2_k127_94631_6 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000001879 173.0
PYH2_k127_94631_7 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000006718 147.0
PYH2_k127_94941_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1058.0
PYH2_k127_94941_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 596.0
PYH2_k127_94941_10 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00004446 49.0
PYH2_k127_94941_2 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001495 279.0
PYH2_k127_94941_3 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004454 276.0
PYH2_k127_94941_4 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008211 267.0
PYH2_k127_94941_5 PFAM Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000002259 258.0
PYH2_k127_94941_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000008052 136.0
PYH2_k127_94941_7 outer membrane lipoprotein carrier protein LolA K03634 - - 0.000000000000000000000000000000006501 137.0
PYH2_k127_94941_8 Universal stress protein - - - 0.000000000000000000004214 104.0
PYH2_k127_94941_9 amine dehydrogenase activity K02035 - - 0.0000002887 64.0
PYH2_k127_952110_0 radical SAM domain protein K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 520.0
PYH2_k127_952110_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 353.0
PYH2_k127_952110_2 PFAM Stage II sporulation protein E (SpoIIE) - - - 0.000000000000000000000000000000000000000000000001809 186.0
PYH2_k127_952110_3 PFAM NADH ubiquinone oxidoreductase complex I intermediate-associated protein 30 - - - 0.00000000000000000000000000000009322 130.0
PYH2_k127_956922_0 GYD domain - - - 0.000000000000000000000000000000000002225 144.0
PYH2_k127_956922_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000173 92.0
PYH2_k127_970492_0 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 473.0
PYH2_k127_970492_1 glycosyl transferase family 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 423.0
PYH2_k127_970492_2 Peptidase M56 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 415.0
PYH2_k127_970492_3 - - - - 0.0000000000000000000000000000000000000000000000000732 189.0
PYH2_k127_970492_4 TonB-dependent receptor K02014 - - 0.000000000000000000000000000000000000000000003773 188.0
PYH2_k127_970492_5 23S rRNA-intervening sequence protein - - - 0.000000000001344 69.0
PYH2_k127_972465_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.435e-243 763.0
PYH2_k127_972465_1 Acyl transferase domain - - - 1.33e-239 756.0
PYH2_k127_972465_2 PFAM LmbE family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 583.0
PYH2_k127_975990_0 ABC transporter C-terminal domain K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 605.0
PYH2_k127_975990_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 481.0
PYH2_k127_975990_10 Domain of unknown function (DUF4416) - - - 0.00000000000000000000000000000000000000000000000001129 185.0
PYH2_k127_975990_11 Regulatory protein MarR - - - 0.00000000000000000000000001179 115.0
PYH2_k127_975990_12 4Fe-4S binding domain - - - 0.0000000000000000000000008342 115.0
PYH2_k127_975990_14 Glycogen debranching enzyme - - - 0.000000002311 61.0
PYH2_k127_975990_2 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 472.0
PYH2_k127_975990_3 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 439.0
PYH2_k127_975990_4 Glycosyl transferase family 21 K19003 - 2.4.1.336 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005896 394.0
PYH2_k127_975990_5 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 364.0
PYH2_k127_975990_6 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 327.0
PYH2_k127_975990_7 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003501 288.0
PYH2_k127_975990_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001036 300.0
PYH2_k127_975990_9 Uncharacterized protein conserved in bacteria (DUF2334) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004071 282.0
PYH2_k127_993788_0 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 343.0
PYH2_k127_993788_1 Major Facilitator Superfamily K08191 - - 0.000000000000000000000000000000000000000000000000000000000000001441 231.0
PYH2_k127_993828_0 PFAM Integrase catalytic - - - 3.404e-213 673.0
PYH2_k127_993828_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 403.0
PYH2_k127_993828_2 IstB-like ATP binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 335.0
PYH2_k127_993828_3 Integrase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 296.0
PYH2_k127_993828_4 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004064 284.0
PYH2_k127_993828_6 DNA methylAse - - - 0.00000000000000000000000002652 113.0
PYH2_k127_993828_7 - - - - 0.0000007311 57.0
PYH2_k127_997430_0 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 595.0
PYH2_k127_997430_1 protein kinase activity K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 379.0
PYH2_k127_997430_2 WD40 domain protein beta Propeller K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 349.0