Overview

ID MAG03202
Name PYH2_bin.6
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order Thermoanaerobaculales
Family Thermoanaerobaculaceae
Genus RBG-13-68-16
Species
Assembly information
Completeness (%) 79.05
Contamination (%) 3.34
GC content (%) 68.0
N50 (bp) 5,361
Genome size (bp) 2,235,528

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2090

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_100159_0 Dehydrogenase E1 component K00164,K01616 - 1.2.4.2,4.1.1.71 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 585.0
PYH2_k127_1007788_0 magnesium chelatase K03405 - 6.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 545.0
PYH2_k127_1007788_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 389.0
PYH2_k127_1007788_2 ferric iron binding K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000008685 182.0
PYH2_k127_1007788_3 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000001644 84.0
PYH2_k127_1014228_0 Sugar transferase - - - 0.00000000000000000000000000000000000000148 148.0
PYH2_k127_1019636_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 409.0
PYH2_k127_1019636_1 peptidase dimerisation domain K01295 - 3.4.17.11 0.000002725 49.0
PYH2_k127_1025602_0 Mechanosensitive ion channel K16052 - - 0.00000000000000000000000001446 113.0
PYH2_k127_1025602_1 4-amino-4-deoxy-L-arabinose transferase activity K14340 - - 0.000000006629 68.0
PYH2_k127_1027795_0 TIGRFAM MazG family protein K02428,K02499,K04765 - 3.6.1.66,3.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000004015 267.0
PYH2_k127_1027795_1 Domain of unknown function (DUF1844) - - - 0.0000009893 57.0
PYH2_k127_1032531_0 filamentation induced by cAMP protein Fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 514.0
PYH2_k127_1032531_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K09384 - - 0.0000000000000000000000000000000000000000000000000000000000000001911 237.0
PYH2_k127_1038392_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 397.0
PYH2_k127_1038392_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000006627 230.0
PYH2_k127_1038392_2 ApaG domain K06195 - - 0.00000000000000000000000000000000000000003966 164.0
PYH2_k127_1038392_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000007691 103.0
PYH2_k127_1038392_4 Protease prsW family - - - 0.000004491 55.0
PYH2_k127_1051168_0 Elongation factor SelB winged helix 3 K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 329.0
PYH2_k127_1051168_1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K00992 - 2.7.7.99 0.000000000000000000000001022 115.0
PYH2_k127_1051168_2 PFAM Adenylate cyclase K05873 - 4.6.1.1 0.00000000000000000000009373 106.0
PYH2_k127_1051168_3 Helix-hairpin-helix motif K02237 - - 0.00000000000000001043 85.0
PYH2_k127_1061607_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 513.0
PYH2_k127_1061607_1 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007402 429.0
PYH2_k127_1061607_2 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.00000000000000000000000000000000000000000000007973 178.0
PYH2_k127_1061607_3 RNA pseudouridylate synthase - - - 0.0000000000000000000000000000000000000000001074 171.0
PYH2_k127_1061607_4 PFAM regulatory protein TetR K13770 - - 0.0000000000000000000000000000000000000001282 159.0
PYH2_k127_1061607_5 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000000000000008883 158.0
PYH2_k127_1061607_6 Sensor histidine kinase, HAMP domain-containing K07644 - 2.7.13.3 0.00000000000000009633 89.0
PYH2_k127_1063036_0 Sugar ABC transporter permease K10109,K15770,K15771 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005104 621.0
PYH2_k127_1063036_1 Bacterial extracellular solute-binding protein K10108,K15770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 545.0
PYH2_k127_1063036_2 Binding-protein-dependent transport system inner membrane component K10110,K15772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 445.0
PYH2_k127_1065429_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 1.195e-230 722.0
PYH2_k127_1072953_0 Carbon starvation protein K06200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003483 593.0
PYH2_k127_1072953_1 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 494.0
PYH2_k127_1072953_2 signal peptide processing K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002441 282.0
PYH2_k127_1082370_0 aminopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000806 406.0
PYH2_k127_1082370_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016491,GO:0016651,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 358.0
PYH2_k127_1082370_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000007588 165.0
PYH2_k127_1084092_0 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 403.0
PYH2_k127_1084092_1 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000000002018 219.0
PYH2_k127_1084092_2 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000000000001152 201.0
PYH2_k127_1084092_3 Thiamin pyrophosphokinase, vitamin B1 binding domain K00949 - 2.7.6.2 0.00000000000000000004659 98.0
PYH2_k127_1084092_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000565 83.0
PYH2_k127_1095788_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 379.0
PYH2_k127_1095788_1 SCO1/SenC K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0032843,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000502 88.0
PYH2_k127_1098967_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000217 516.0
PYH2_k127_1098967_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 334.0
PYH2_k127_1098967_2 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000000000000000000000000000000000000000005576 208.0
PYH2_k127_1098967_3 - - - - 0.0000000000000000002499 93.0
PYH2_k127_1098967_4 NADH-Ubiquinone oxidoreductase (complex I), chain 5 K00341 - 1.6.5.3 0.0007843 43.0
PYH2_k127_1100523_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 535.0
PYH2_k127_1100523_1 Amino-transferase class IV K00826 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004084,GO:0005488,GO:0006082,GO:0006464,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0018272,GO:0018352,GO:0019538,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0036211,GO:0040007,GO:0043094,GO:0043102,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071265,GO:0071267,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002914 367.0
PYH2_k127_1100523_10 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000002108 125.0
PYH2_k127_1100523_11 - K01992 - - 0.000000000000000000000000005167 121.0
PYH2_k127_1100523_12 Phospholipase B - - - 0.00000000000004722 84.0
PYH2_k127_1100523_2 PFAM NAD-dependent glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003059 293.0
PYH2_k127_1100523_3 LytTr DNA-binding domain K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001181 278.0
PYH2_k127_1100523_4 Belongs to the CinA family K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000003447 274.0
PYH2_k127_1100523_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002462 265.0
PYH2_k127_1100523_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000925 260.0
PYH2_k127_1100523_7 NIF3 (NGG1p interacting factor 3) K22391 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009314,GO:0009628,GO:0010212,GO:0042802,GO:0043167,GO:0043169,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0050896 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000002886 243.0
PYH2_k127_1100523_8 membrane - - - 0.0000000000000000000000000000000000000000000000000002969 198.0
PYH2_k127_1100523_9 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000007724 164.0
PYH2_k127_1110574_0 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 470.0
PYH2_k127_1110574_1 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001552 282.0
PYH2_k127_1110574_2 Lytic transglycosylase catalytic K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001762 274.0
PYH2_k127_1110574_3 - - - - 0.000001185 57.0
PYH2_k127_1117119_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001969 290.0
PYH2_k127_1117119_1 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007948 279.0
PYH2_k127_1117119_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000001953 111.0
PYH2_k127_1117119_3 MacB-like periplasmic core domain K02004 - - 0.000000000005829 68.0
PYH2_k127_1117119_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00009773 55.0
PYH2_k127_1121408_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1563.0
PYH2_k127_1126685_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 1.981e-197 630.0
PYH2_k127_1126685_1 catalyzes the conversion of acetate and CoA to acetyl-CoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003981 270.0
PYH2_k127_1126685_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000006948 110.0
PYH2_k127_1150305_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 352.0
PYH2_k127_1150305_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.00000000000000000000001214 106.0
PYH2_k127_1162979_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009561 279.0
PYH2_k127_1162979_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000004765 187.0
PYH2_k127_1162979_2 Domain of unknown function (DUF4136) - - - 0.000000000000000000000001499 117.0
PYH2_k127_1162979_3 nucleoside 2-deoxyribosyltransferase - GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009123,GO:0009125,GO:0009159,GO:0009162,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070694,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 - 0.0000000000000000642 89.0
PYH2_k127_1162979_4 long-chain fatty acid transport protein - - - 0.0000000002327 69.0
PYH2_k127_1162979_5 - - - - 0.0003317 53.0
PYH2_k127_1165866_0 PHP domain protein K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 437.0
PYH2_k127_1165866_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 323.0
PYH2_k127_1165866_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 329.0
PYH2_k127_1165866_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006947 281.0
PYH2_k127_1165866_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000004233 228.0
PYH2_k127_1165866_5 Lumazine binding domain K00793 GO:0003674,GO:0003824,GO:0004746,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.9 0.0000000000000000000000000000000000000000000000000000921 193.0
PYH2_k127_1165866_6 Tetratricopeptide repeat - - - 0.00000000000007607 81.0
PYH2_k127_1165866_7 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000001394 60.0
PYH2_k127_1165866_8 Roadblock/LC7 domain - - - 0.0000001111 59.0
PYH2_k127_1196724_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003685 441.0
PYH2_k127_1196724_1 Alpha/beta hydrolase family K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 316.0
PYH2_k127_1196724_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 305.0
PYH2_k127_1196724_3 TIGRFAM channel protein, hemolysin III family K11068 - - 0.00000000000000000000000000000000000000000000000000000000000000000006393 243.0
PYH2_k127_1197278_0 Saccharopine dehydrogenase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 471.0
PYH2_k127_1197278_1 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000003843 234.0
PYH2_k127_1197278_2 Transcription factor zinc-finger K09981 - - 0.00000000000000000002083 97.0
PYH2_k127_1208746_0 creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000001287 206.0
PYH2_k127_1208746_1 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000000000000000000000000000000000000000001078 191.0
PYH2_k127_1208746_2 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.0000000008418 59.0
PYH2_k127_1212401_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 6.004e-235 742.0
PYH2_k127_1212401_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000003094 68.0
PYH2_k127_1212401_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000001696 69.0
PYH2_k127_1235896_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 8.347e-195 617.0
PYH2_k127_1235896_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002051 285.0
PYH2_k127_1235896_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000001824 217.0
PYH2_k127_1235896_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000001946 172.0
PYH2_k127_1235896_4 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000004684 163.0
PYH2_k127_1235896_5 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000004239 140.0
PYH2_k127_1235896_6 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.000000000000000000000000000000002558 129.0
PYH2_k127_1235896_7 Ribosomal protein L36 K02919 - - 0.0000000000003433 69.0
PYH2_k127_124122_0 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008068 353.0
PYH2_k127_124122_1 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000002091 109.0
PYH2_k127_1258606_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 461.0
PYH2_k127_1258606_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003147 398.0
PYH2_k127_1258606_10 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000001273 166.0
PYH2_k127_1258606_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000007505 160.0
PYH2_k127_1258606_12 repeat-containing protein - - - 0.0000000000000000000000000000000000001461 162.0
PYH2_k127_1258606_13 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000216 134.0
PYH2_k127_1258606_14 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0008150,GO:0040007 - 0.00000000000000000000000000004993 122.0
PYH2_k127_1258606_15 Belongs to the UPF0109 family K06960 - - 0.0000000000000000000000001505 109.0
PYH2_k127_1258606_16 Could be involved in septation K06412 - - 0.000000000000000000002239 97.0
PYH2_k127_1258606_17 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000004616 83.0
PYH2_k127_1258606_18 - - - - 0.000000001717 67.0
PYH2_k127_1258606_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001225 285.0
PYH2_k127_1258606_3 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004237 252.0
PYH2_k127_1258606_4 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000006536 234.0
PYH2_k127_1258606_5 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000000000000000006349 233.0
PYH2_k127_1258606_6 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000001026 181.0
PYH2_k127_1258606_7 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000294 176.0
PYH2_k127_1258606_8 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000003387 178.0
PYH2_k127_1258606_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0040007,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000006606 179.0
PYH2_k127_1262422_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000004496 265.0
PYH2_k127_1262422_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000001185 231.0
PYH2_k127_1262422_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000005088 214.0
PYH2_k127_1262422_3 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000000002004 150.0
PYH2_k127_1262422_4 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000000003204 97.0
PYH2_k127_1262422_5 positive regulation of macromolecule biosynthetic process K03973 - - 0.00000000009083 64.0
PYH2_k127_1337514_0 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 343.0
PYH2_k127_1337514_1 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000008519 213.0
PYH2_k127_1370739_0 3-isopropylmalate dehydratase activity K01703,K01704,K01705 - 4.2.1.33,4.2.1.35,4.2.1.36 9.489e-202 638.0
PYH2_k127_1370739_1 MmgE/PrpD family K01720 - 4.2.1.79 0.000000000000000000000008041 102.0
PYH2_k127_1435357_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 452.0
PYH2_k127_1435357_1 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003287 245.0
PYH2_k127_1460018_0 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 394.0
PYH2_k127_1460018_1 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000007239 190.0
PYH2_k127_1460018_2 - - - - 0.000000000000000006786 93.0
PYH2_k127_1465958_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 312.0
PYH2_k127_1465958_1 PFAM NAD-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000007318 169.0
PYH2_k127_1536553_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1045.0
PYH2_k127_1536553_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 7.881e-203 644.0
PYH2_k127_1536553_10 Methyltransferase domain - - - 0.00000000000000000000000000000000000000009195 168.0
PYH2_k127_1536553_11 DinB family - - - 0.0000000000000000000000001341 112.0
PYH2_k127_1536553_12 Sugar (and other) transporter - - - 0.000000000000000000002895 96.0
PYH2_k127_1536553_14 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000001296 71.0
PYH2_k127_1536553_2 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 415.0
PYH2_k127_1536553_3 Glycosyl transferase, family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 368.0
PYH2_k127_1536553_4 COG1682 ABC-type polysaccharide polyol phosphate export systems, permease component K09690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 324.0
PYH2_k127_1536553_5 Glycosyl transferase, family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003191 289.0
PYH2_k127_1536553_6 lipopolysaccharide heptosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000002046 233.0
PYH2_k127_1536553_7 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000188 224.0
PYH2_k127_1536553_8 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000477 171.0
PYH2_k127_1536553_9 Methyltransferase domain - - - 0.000000000000000000000000000000000000000006938 168.0
PYH2_k127_1551180_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 3.386e-236 752.0
PYH2_k127_1551180_1 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002037 470.0
PYH2_k127_1551180_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002955 264.0
PYH2_k127_1551180_3 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000004291 211.0
PYH2_k127_1551180_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.0000000000000000000000000000000000000000000000000001193 194.0
PYH2_k127_1551180_5 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000002669 197.0
PYH2_k127_1551180_6 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000001485 164.0
PYH2_k127_1551180_7 Pfam:N_methyl_2 K02456 - - 0.0000000000000000000000000000000002732 137.0
PYH2_k127_1551180_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000008517 81.0
PYH2_k127_1551180_9 general secretion pathway protein - - - 0.00000000000003082 82.0
PYH2_k127_1561934_0 Nickel-dependent hydrogenase K06281 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 310.0
PYH2_k127_1561934_1 Ni Fe-hydrogenase, b-type cytochrome subunit K03620 - - 0.0000000000000000000000000000000000000000000000000002715 193.0
PYH2_k127_1561934_2 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000001984 188.0
PYH2_k127_1561934_3 hydrogenase expression formation protein K03605 - - 0.0000000000000000003965 94.0
PYH2_k127_1568238_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 441.0
PYH2_k127_1568238_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 403.0
PYH2_k127_1568238_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 321.0
PYH2_k127_1568238_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000002193 119.0
PYH2_k127_1570370_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 454.0
PYH2_k127_1570370_1 Elongation factor SelB, winged helix K03833 - - 0.000000000001633 72.0
PYH2_k127_1873568_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.979e-235 743.0
PYH2_k127_1873568_1 curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 308.0
PYH2_k127_1873568_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000002052 126.0
PYH2_k127_1874883_0 Memo-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002098 276.0
PYH2_k127_1874883_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002412 259.0
PYH2_k127_1874883_2 COG3901 Regulator of nitric oxide reductase transcription K19339,K19343 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001929 243.0
PYH2_k127_1874883_3 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000002021 247.0
PYH2_k127_1874883_4 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000002715 165.0
PYH2_k127_1897703_0 Alpha amylase, catalytic domain - - - 3.865e-243 758.0
PYH2_k127_1897703_1 Glycogen debranching enzyme - - - 8.946e-198 621.0
PYH2_k127_1900883_0 TIGRFAM cysteine desulfurase family protein, VC1184 subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 506.0
PYH2_k127_1900883_1 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005818 326.0
PYH2_k127_1900883_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000002314 243.0
PYH2_k127_1900883_3 - - - - 0.00000000000000000000000000000001368 137.0
PYH2_k127_1900883_4 transporter K07238,K11021 - - 0.00000000000000000000002354 109.0
PYH2_k127_1900883_5 Dodecin K09165 - - 0.00000000000000004059 87.0
PYH2_k127_1900883_6 Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit K04762 - - 0.0000000003752 66.0
PYH2_k127_1915222_0 Amidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 605.0
PYH2_k127_1915222_1 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 458.0
PYH2_k127_1915222_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 445.0
PYH2_k127_1915222_3 LmbE family - - - 0.000000000000000000000000000000000000000000000000000000002074 207.0
PYH2_k127_1915222_4 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000002127 72.0
PYH2_k127_1915222_5 response regulator, receiver K11527 - 2.7.13.3 0.0007966 51.0
PYH2_k127_1923035_0 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006508 241.0
PYH2_k127_1923035_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000002786 233.0
PYH2_k127_1923035_2 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.00000000000000000000000000000000000000000000000000002684 196.0
PYH2_k127_1923035_3 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.00000000000000000000000000000000000000000000000001478 192.0
PYH2_k127_1923035_4 DNA-directed 5'-3' RNA polymerase activity K03060 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0030312,GO:0030880,GO:0032774,GO:0032991,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0061695,GO:0071704,GO:0071944,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576,GO:1902494,GO:1990234 2.7.7.6 0.0007193 49.0
PYH2_k127_1927167_0 PFAM Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 343.0
PYH2_k127_1927167_1 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 300.0
PYH2_k127_1927167_2 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000001198 186.0
PYH2_k127_1927167_3 FHA domain K07315 - 3.1.3.3 0.000000000000000000000000000000000006744 154.0
PYH2_k127_1927167_4 Protein of unknown function, DUF255 - - - 0.0000000000000000000000000003496 122.0
PYH2_k127_1927167_5 - - - - 0.000004229 57.0
PYH2_k127_1930452_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 387.0
PYH2_k127_1930452_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000255 258.0
PYH2_k127_1930452_2 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000003196 213.0
PYH2_k127_1930452_3 YbbR-like protein - - - 0.0000000001176 72.0
PYH2_k127_1936098_0 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 550.0
PYH2_k127_1936098_1 gluconolactonase K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 343.0
PYH2_k127_1936098_2 Outer membrane protein beta-barrel domain - - - 0.0000000000000000000000000000000000002973 148.0
PYH2_k127_1936098_3 - - - - 0.000000000000000000000000000000000001694 145.0
PYH2_k127_1936098_4 - - - - 0.000000000000000000000000000000000711 139.0
PYH2_k127_1936098_5 - - - - 0.000000000000000009701 88.0
PYH2_k127_1936098_6 - - - - 0.00000000000000002497 86.0
PYH2_k127_194230_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 426.0
PYH2_k127_194230_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 359.0
PYH2_k127_194230_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 325.0
PYH2_k127_194230_3 pfam abc K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003004 261.0
PYH2_k127_194230_4 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002276 270.0
PYH2_k127_194230_5 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001381 261.0
PYH2_k127_194230_6 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000001031 129.0
PYH2_k127_194230_7 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000006719 79.0
PYH2_k127_194230_8 PBS lyase HEAT-like repeat - - - 0.000000000007271 79.0
PYH2_k127_194230_9 cyclic diguanylate phosphodiesterase - - - 0.0000000007509 70.0
PYH2_k127_1945698_0 COG NOG10142 non supervised orthologous group - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000817 517.0
PYH2_k127_1955004_0 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 346.0
PYH2_k127_1955004_1 ABC 3 transport family K02075 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 334.0
PYH2_k127_1955004_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 305.0
PYH2_k127_1966851_0 mRNA catabolic process K06950,K09163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000612 276.0
PYH2_k127_1966851_1 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000005139 250.0
PYH2_k127_1966851_2 protein kinase activity K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000006253 241.0
PYH2_k127_1966851_3 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000138 216.0
PYH2_k127_1966851_4 COGs COG1629 Outer membrane receptor protein mostly Fe transport K02014 - - 0.000000000000000000000000000000000000000000000007749 198.0
PYH2_k127_1966851_5 MmgE/PrpD family K01720 - 4.2.1.79 0.0000000000000000000000002938 114.0
PYH2_k127_1966851_6 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000000009548 121.0
PYH2_k127_1966851_7 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000005478 109.0
PYH2_k127_1966851_8 Peptidase family M28 - - - 0.000000003307 68.0
PYH2_k127_1966851_9 protein kinase activity K12132 - 2.7.11.1 0.0007497 46.0
PYH2_k127_1967829_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 313.0
PYH2_k127_1967829_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000004562 221.0
PYH2_k127_1969874_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 436.0
PYH2_k127_1969874_1 receptor K16087 - - 0.00000000000000000000000000000000000000000000001247 194.0
PYH2_k127_1969874_2 - - - - 0.0001037 51.0
PYH2_k127_1985125_0 Deacetylases, including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 451.0
PYH2_k127_1985125_1 TIGRFAM PAS domain S-box - - - 0.000000000000000000000000000000000000000000000001222 188.0
PYH2_k127_1985125_2 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000001381 186.0
PYH2_k127_1985125_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000004473 163.0
PYH2_k127_1985125_4 PFAM peptidase S13 D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000005291 151.0
PYH2_k127_1991016_0 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0002094 51.0
PYH2_k127_1991016_1 Bacterial Ig-like domain (group 3) - - - 0.0003343 52.0
PYH2_k127_2005691_0 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 501.0
PYH2_k127_2005691_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000003323 156.0
PYH2_k127_2005691_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000141 79.0
PYH2_k127_2005691_3 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 0.0000005593 55.0
PYH2_k127_2026979_0 5-oxoprolinase (ATP-hydrolyzing) activity K07160 - - 0.00000000000000000000000000000000000000000000000000000000000000000002473 243.0
PYH2_k127_2026979_1 PFAM LmbE family protein - - - 0.00000000000000000000000000000000000000000000000000000001496 205.0
PYH2_k127_2026979_2 PFAM Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000005295 181.0
PYH2_k127_2026979_3 major facilitator superfamily - - - 0.00000000005533 64.0
PYH2_k127_203632_0 Phosphoenolpyruvate carboxykinase K01610 - 4.1.1.49 6.185e-210 677.0
PYH2_k127_203632_1 phosphoglycerate mutase family - - - 0.000000000000000000000000000000000000000000000000000000000000003073 226.0
PYH2_k127_203632_2 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000001368 129.0
PYH2_k127_203632_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000003554 124.0
PYH2_k127_203632_4 - - - - 0.00000000000001519 81.0
PYH2_k127_2038564_0 Belongs to the GSP D family K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000001161 242.0
PYH2_k127_2038564_1 PFAM Fimbrial assembly family protein K02663 - - 0.0000001653 61.0
PYH2_k127_2045620_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 3.287e-224 704.0
PYH2_k127_2045620_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 575.0
PYH2_k127_2045620_2 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 357.0
PYH2_k127_2045620_3 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000008394 182.0
PYH2_k127_2045620_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000001718 57.0
PYH2_k127_204622_0 Belongs to the peptidase S16 family K01338,K04076,K04770 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 497.0
PYH2_k127_204622_1 - - - - 0.0000000000000000000000000000009303 125.0
PYH2_k127_2056177_0 modulates the activities of several proteins which are inactive in their K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000004728 236.0
PYH2_k127_2056177_1 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000001003 148.0
PYH2_k127_2056177_2 auxin-activated signaling pathway K07088 - - 0.000000000003337 76.0
PYH2_k127_2088915_0 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000001702 228.0
PYH2_k127_2088915_1 Beta-lactamase - - - 0.000000000000000000003285 98.0
PYH2_k127_2090360_0 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004475 266.0
PYH2_k127_2090360_1 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002812 267.0
PYH2_k127_2090360_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000028,GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003723,GO:0003729,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0031167,GO:0032259,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070475,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.182 0.00000000000000000000000000000000000001387 154.0
PYH2_k127_2090360_3 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000004661 146.0
PYH2_k127_2090360_4 Serine aminopeptidase, S33 K16434 - - 0.0000000000000000000003003 107.0
PYH2_k127_2090360_5 DinB superfamily - - - 0.0000001878 60.0
PYH2_k127_2115488_0 PFAM Carbamoyl-phosphate synthase L chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 595.0
PYH2_k127_2115488_1 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000001727 198.0
PYH2_k127_2124505_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005964 385.0
PYH2_k127_2124505_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 293.0
PYH2_k127_2124505_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000007422 231.0
PYH2_k127_2124505_3 Ribosomal protein L16p/L10e K02878 - - 0.000000000000000000000000000000000000000000000000000000003753 200.0
PYH2_k127_2124505_4 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000005978 178.0
PYH2_k127_2124505_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000003406 177.0
PYH2_k127_2124505_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000008838 149.0
PYH2_k127_2124505_7 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000216 114.0
PYH2_k127_2124505_8 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005844,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042788,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000009163 93.0
PYH2_k127_2124505_9 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000005742 80.0
PYH2_k127_2127131_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000001101 164.0
PYH2_k127_2127131_1 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000001655 128.0
PYH2_k127_2127131_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000004797 120.0
PYH2_k127_2127131_3 synthase K09458 - 2.3.1.179 0.0000000001101 72.0
PYH2_k127_2127131_4 Protein of unknown function (DUF465) K09794 - - 0.000006736 51.0
PYH2_k127_2134434_0 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 429.0
PYH2_k127_2134434_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000002744 152.0
PYH2_k127_2134434_2 von Willebrand factor, type A - - - 0.00000000000000000000000000001653 135.0
PYH2_k127_2155351_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 508.0
PYH2_k127_2155351_1 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000007444 186.0
PYH2_k127_2155351_2 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000000000000002545 129.0
PYH2_k127_2155351_3 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000000008067 102.0
PYH2_k127_2155351_4 - - - - 0.0000000000001388 76.0
PYH2_k127_2155351_5 histone H2A K63-linked ubiquitination - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0031323,GO:0031326,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.000000000874 68.0
PYH2_k127_2160048_0 ABC transporter K06020 - 3.6.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007556 337.0
PYH2_k127_2160048_1 methyltransferase K13311,K13326,K21335 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983 2.1.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 304.0
PYH2_k127_2160048_2 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001044 234.0
PYH2_k127_2160048_3 methyltransferase - - - 0.0000000000000000000000000676 117.0
PYH2_k127_2189658_0 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002209 255.0
PYH2_k127_2189658_1 Nickel-dependent hydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000003893 226.0
PYH2_k127_2189658_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.00000000000000000000000000000000002148 137.0
PYH2_k127_2226551_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 7.659e-285 913.0
PYH2_k127_2226551_1 Aldehyde dehydrogenase family K00128 - 1.2.1.3 5.271e-219 689.0
PYH2_k127_2226551_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.224e-218 688.0
PYH2_k127_2226551_3 N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity K00819,K00821 GO:0003674,GO:0003824,GO:0004587,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016740,GO:0016769,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.6.1.11,2.6.1.13,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 587.0
PYH2_k127_2226551_4 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 346.0
PYH2_k127_2226551_5 PFAM glucosamine galactosamine-6-phosphate isomerase K01057 - 3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000005177 247.0
PYH2_k127_2226551_6 PFAM thioesterase superfamily - - - 0.00000000000003819 79.0
PYH2_k127_2236411_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 423.0
PYH2_k127_2236411_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000000000000211 225.0
PYH2_k127_2236411_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000003532 177.0
PYH2_k127_2236411_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000001155 179.0
PYH2_k127_2236411_4 SpoIVB peptidase S55 - - - 0.0000000000000000000000000000000000000000001676 179.0
PYH2_k127_2236411_5 Protein of unknown function (DUF1684) K09164 - - 0.00000000000000000000000000005382 124.0
PYH2_k127_2236411_6 Required for chromosome condensation and partitioning K03529 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000009463 92.0
PYH2_k127_2236411_7 COG3307 Lipid A core - O-antigen ligase and related enzymes - - - 0.00001706 58.0
PYH2_k127_2239386_0 heat shock protein binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000636 274.0
PYH2_k127_2239386_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004922 261.0
PYH2_k127_2239386_2 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000001391 206.0
PYH2_k127_2239386_3 Methyl-accepting chemotaxis sensory transducer with Pas Pac sensor K02660 - - 0.000000000000000000000000000000000000000000000000000004684 219.0
PYH2_k127_2239386_4 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000004953 153.0
PYH2_k127_2239386_5 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000000000000000000002687 124.0
PYH2_k127_2239386_6 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000001629 109.0
PYH2_k127_2239903_0 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 359.0
PYH2_k127_2239903_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001369 343.0
PYH2_k127_2239903_2 GYD domain - - - 0.000000000000000000000000000001557 124.0
PYH2_k127_2242475_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 439.0
PYH2_k127_2242475_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 297.0
PYH2_k127_2242475_2 - - - - 0.00000000000000000000001043 105.0
PYH2_k127_2242475_3 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.000000000000000001626 85.0
PYH2_k127_2242475_4 Protein of unknown function (DUF2723) - - - 0.000000000005897 79.0
PYH2_k127_2260484_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 517.0
PYH2_k127_2260484_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004782 233.0
PYH2_k127_2260484_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000525 124.0
PYH2_k127_2260484_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000001359 114.0
PYH2_k127_2296268_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 449.0
PYH2_k127_2296268_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 344.0
PYH2_k127_2296268_2 PFAM Outer membrane efflux protein - - - 0.000007015 53.0
PYH2_k127_2304595_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 482.0
PYH2_k127_2314144_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005515,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0046983,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 4.767e-259 813.0
PYH2_k127_2356263_0 Zn_pept - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008569 371.0
PYH2_k127_2356263_1 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003151 295.0
PYH2_k127_2356263_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000000000000000000000002086 212.0
PYH2_k127_2356263_3 Ankyrin repeats (many copies) - - - 0.0000000000000004667 86.0
PYH2_k127_23714_0 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 5.943e-230 724.0
PYH2_k127_23714_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 384.0
PYH2_k127_23714_2 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000003789 261.0
PYH2_k127_23714_3 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000002563 154.0
PYH2_k127_23714_4 TIGRFAM Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.000000000000000000000000000000007399 132.0
PYH2_k127_23714_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000002808 119.0
PYH2_k127_23714_6 succinate dehydrogenase activity K00242,K00246 - - 0.0000000000000004998 82.0
PYH2_k127_23714_7 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0004470,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019752,GO:0030060,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 1.1.1.37 0.0000402 49.0
PYH2_k127_2517152_0 Peptidase family M1 domain - - - 0.0 1135.0
PYH2_k127_2517152_1 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 394.0
PYH2_k127_2517152_2 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 297.0
PYH2_k127_2517152_3 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001827 267.0
PYH2_k127_2517152_4 chaperone-mediated protein folding K11935 - - 0.0001753 53.0
PYH2_k127_2577549_0 PFAM Uracil DNA glycosylase superfamily K21929 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000001082 246.0
PYH2_k127_2577549_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000001008 154.0
PYH2_k127_2577549_3 Ubiquinone biosynthesis protein UbiA K02548 - 2.5.1.74 0.000000000000000000000000000000003706 144.0
PYH2_k127_2577549_4 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000001122 134.0
PYH2_k127_2577549_5 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000002533 122.0
PYH2_k127_2577549_6 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000001755 107.0
PYH2_k127_2577549_7 Cyclic nucleotide-monophosphate binding domain - - - 0.0000548 56.0
PYH2_k127_259873_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 419.0
PYH2_k127_259873_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 370.0
PYH2_k127_259873_2 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 323.0
PYH2_k127_259873_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005803 241.0
PYH2_k127_259873_4 phosphorelay signal transduction system K02437 - - 0.000000000000000001455 94.0
PYH2_k127_2802710_0 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000009208 157.0
PYH2_k127_2802710_1 MMPL family K07003 - - 0.0000000000000000000000000005619 131.0
PYH2_k127_2803300_0 Oligoendopeptidase f - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 615.0
PYH2_k127_2805270_0 FMN binding - - - 2.688e-249 778.0
PYH2_k127_2805270_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.000000000000000000001312 96.0
PYH2_k127_2805270_2 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase K00162,K21417 - 1.2.4.1 0.00005684 46.0
PYH2_k127_2807452_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008275 475.0
PYH2_k127_2807452_1 Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003793 266.0
PYH2_k127_2807452_2 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000009598 102.0
PYH2_k127_2807452_3 N-acetyltransferase - - - 0.00000000000000000000144 105.0
PYH2_k127_2809930_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003404 280.0
PYH2_k127_2809930_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000004559 169.0
PYH2_k127_2809930_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000003821 166.0
PYH2_k127_2809930_3 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000005334 115.0
PYH2_k127_2809930_4 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000000000000217 107.0
PYH2_k127_2809930_5 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000004013 89.0
PYH2_k127_2812250_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 2.244e-279 871.0
PYH2_k127_2812434_0 Large extracellular alpha-helical protein - - - 0.000000000000000000000000000000000003022 162.0
PYH2_k127_2815339_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 335.0
PYH2_k127_2815339_1 transcriptional regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009003 303.0
PYH2_k127_2815339_2 Flavodoxin-like fold K00355 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000002705 252.0
PYH2_k127_2815339_3 ABC transporter K09812 GO:0000910,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0008356,GO:0009966,GO:0009987,GO:0010646,GO:0016020,GO:0016043,GO:0022402,GO:0022603,GO:0022607,GO:0023051,GO:0032506,GO:0042173,GO:0043937,GO:0043938,GO:0044085,GO:0044464,GO:0045595,GO:0045597,GO:0045881,GO:0048518,GO:0048522,GO:0048583,GO:0050789,GO:0050793,GO:0050794,GO:0051094,GO:0051301,GO:0065007,GO:0070297,GO:0071840,GO:0071944,GO:0090529,GO:1902531 - 0.000000000000000000000000000000000000000000000000000000000000000009896 238.0
PYH2_k127_2815339_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000114 119.0
PYH2_k127_2815339_5 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0003824,GO:0005488,GO:0005507,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0046983,GO:0055114 - 0.0000000000000000000000002525 114.0
PYH2_k127_2815339_6 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.00000000000498 76.0
PYH2_k127_2815339_7 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000006203 62.0
PYH2_k127_2815339_8 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00001675 56.0
PYH2_k127_2816228_0 Amidinotransferase K01482 - 3.5.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009242 300.0
PYH2_k127_2816228_1 Pfam:Arch_ATPase K02450 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001707 289.0
PYH2_k127_2816228_2 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006399 275.0
PYH2_k127_2824587_0 Histidine kinase - - - 0.000000000000000000000000001224 128.0
PYH2_k127_2832237_0 belongs to the aldehyde dehydrogenase family - - - 2.299e-205 654.0
PYH2_k127_2832237_1 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000001844 83.0
PYH2_k127_2832237_2 COG1404 Subtilisin-like serine proteases K20486 - - 0.0000122 48.0
PYH2_k127_2833515_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1023.0
PYH2_k127_2833515_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 608.0
PYH2_k127_2840209_0 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 350.0
PYH2_k127_2840209_1 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000005294 125.0
PYH2_k127_2840209_2 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000002875 94.0
PYH2_k127_2851174_0 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 369.0
PYH2_k127_2851174_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000001929 254.0
PYH2_k127_2851174_2 - - - - 0.0008891 50.0
PYH2_k127_2851596_0 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 418.0
PYH2_k127_2859934_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K14126,K17993 GO:0003674,GO:0005488,GO:0005575,GO:0016151,GO:0032991,GO:0043167,GO:0043169,GO:0044569,GO:0046872,GO:0046914,GO:1902494 1.12.1.3,1.12.1.5,1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 363.0
PYH2_k127_2859934_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 302.0
PYH2_k127_2859934_2 Oxidoreductase NAD-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008369 284.0
PYH2_k127_2859934_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 - 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000001286 216.0
PYH2_k127_2859934_4 hydrogenase maturation protease K03605 - - 0.000000000000000002357 91.0
PYH2_k127_2859934_5 PFAM Rubrerythrin - - - 0.000000000000000002773 85.0
PYH2_k127_2872429_0 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000005528 225.0
PYH2_k127_2873568_0 ADP-glyceromanno-heptose 6-epimerase activity K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 470.0
PYH2_k127_2873568_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 469.0
PYH2_k127_2875551_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000000006742 174.0
PYH2_k127_2875551_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000001688 132.0
PYH2_k127_2875551_2 Peptidase family M23 - - - 0.000000000000000004499 96.0
PYH2_k127_2875551_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000006696 78.0
PYH2_k127_2875551_4 Archease protein family (MTH1598/TM1083) - - - 0.0006108 48.0
PYH2_k127_2890956_0 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 364.0
PYH2_k127_2890956_1 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.00000000005091 72.0
PYH2_k127_2890956_2 TIGRFAM VWFA-related Acidobacterial domain - - - 0.00002022 54.0
PYH2_k127_2894991_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 586.0
PYH2_k127_2894991_1 Cytidylate kinase K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0040007,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.0000000000000000000000000000000000000000000000000008355 192.0
PYH2_k127_2894991_2 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000005453 173.0
PYH2_k127_2894991_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.0000000000000000000000005824 106.0
PYH2_k127_2894991_4 - - - - 0.0004509 46.0
PYH2_k127_2895723_0 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000002309 194.0
PYH2_k127_2895723_1 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B gamma epsilon subunits K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000002919 185.0
PYH2_k127_2895723_2 Histidine kinase - - - 0.00000000000000000000000000000000226 147.0
PYH2_k127_2895723_3 response regulator - - - 0.00000000000000000000000001012 113.0
PYH2_k127_2896954_0 PFAM Cytochrome b b6 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 358.0
PYH2_k127_2896954_1 Outer Membrane Lipoprotein K03098 GO:0005575,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0033554,GO:0044462,GO:0044464,GO:0050896,GO:0051716,GO:0071944 - 0.00000000000000000000001151 104.0
PYH2_k127_2896954_2 Ion channel - - - 0.000000000000000004831 93.0
PYH2_k127_2904841_0 AcrB/AcrD/AcrF family K03296 - - 3.065e-229 730.0
PYH2_k127_2912739_0 General secretory system II, protein E domain protein K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004459 252.0
PYH2_k127_2912739_1 PFAM glycosyl transferase family 9 K02841 - - 0.0000000000000000000000001551 117.0
PYH2_k127_2915629_0 kinase activity K02850 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0044237 - 0.0000000000000000000000000000000000000000000000000000000000001567 228.0
PYH2_k127_2915629_1 - - - - 0.0001373 48.0
PYH2_k127_2917377_0 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000003671 165.0
PYH2_k127_2917377_1 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000000002273 149.0
PYH2_k127_2917377_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000002049 64.0
PYH2_k127_2919788_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007612 389.0
PYH2_k127_2919788_1 to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 385.0
PYH2_k127_2919788_2 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004647 336.0
PYH2_k127_2919788_3 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 306.0
PYH2_k127_2919788_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 294.0
PYH2_k127_2919788_5 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 293.0
PYH2_k127_2919788_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000005814 272.0
PYH2_k127_2919788_7 Belongs to the MraZ family K03925 - - 0.000000000000000000000000009132 117.0
PYH2_k127_2919788_8 SurA N-terminal domain K03771 - 5.2.1.8 0.00000000000000003562 92.0
PYH2_k127_2919788_9 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000005157 83.0
PYH2_k127_2920065_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000002241 126.0
PYH2_k127_2920065_1 4Fe-4S binding domain - - - 0.000000000001902 79.0
PYH2_k127_2920065_2 response regulator receiver K13599 - - 0.00000002927 60.0
PYH2_k127_2921781_0 BMC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001022 278.0
PYH2_k127_2921781_1 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000001006 272.0
PYH2_k127_2921781_2 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000008849 150.0
PYH2_k127_2921781_3 BMC K04027 - - 0.000000000000000000000000000000000444 134.0
PYH2_k127_2921781_4 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000000000001817 108.0
PYH2_k127_2921781_5 Bacterial membrane protein, YfhO - - - 0.000000004104 68.0
PYH2_k127_2927372_0 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000000000001211 220.0
PYH2_k127_2927372_1 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000000000000000000001111 211.0
PYH2_k127_2927372_3 - - - - 0.00002835 52.0
PYH2_k127_2938971_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000244 228.0
PYH2_k127_2938971_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000427 74.0
PYH2_k127_2938971_2 - - - - 0.0001639 54.0
PYH2_k127_2943525_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
PYH2_k127_2943525_1 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006796 283.0
PYH2_k127_2943525_2 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000006768 228.0
PYH2_k127_2943525_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000002889 140.0
PYH2_k127_2943525_4 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.000002278 57.0
PYH2_k127_2943525_5 Tetratricopeptide repeat - - - 0.000009181 51.0
PYH2_k127_2943525_6 TIGRFAM competence protein ComEA helix-hairpin-helix repeat K02237 - - 0.00004446 49.0
PYH2_k127_2946096_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005388 623.0
PYH2_k127_2946096_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 411.0
PYH2_k127_2946096_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004197 279.0
PYH2_k127_2952256_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000002783 252.0
PYH2_k127_2952256_1 DNA mismatch repair protein MutT - - - 0.000000000000000000000000000002731 128.0
PYH2_k127_2952256_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000049 99.0
PYH2_k127_2952256_3 Tetratricopeptide repeats - - - 0.00000001586 67.0
PYH2_k127_2956197_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 384.0
PYH2_k127_2956197_1 DinB family - - - 0.000000000000000000000000000000000000000008363 159.0
PYH2_k127_2958278_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005478 334.0
PYH2_k127_2958278_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000006991 196.0
PYH2_k127_2958278_2 COG4206 Outer membrane cobalamin receptor protein K16092 - - 0.000000000000000000000000000000000000000000000001614 195.0
PYH2_k127_2958278_3 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000074 173.0
PYH2_k127_2958278_4 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.00000000000000000000001563 110.0
PYH2_k127_2958278_5 Protein of unknown function (DUF1573) - - - 0.0000000000000002991 94.0
PYH2_k127_2958278_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 3.6.3.14 0.000000000000002177 79.0
PYH2_k127_2958278_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000266 76.0
PYH2_k127_2958278_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000007594 61.0
PYH2_k127_2958278_9 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00004207 51.0
PYH2_k127_2978047_0 COG1194 A G-specific DNA glycosylase K03575 GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000008971 218.0
PYH2_k127_2978047_1 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000000002844 194.0
PYH2_k127_2982394_0 Amidohydrolase family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 385.0
PYH2_k127_2982394_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000001024 214.0
PYH2_k127_2982394_2 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000007745 123.0
PYH2_k127_2982394_3 DivIVA domain K04074 - - 0.00000000002297 71.0
PYH2_k127_2982394_4 C4-type zinc ribbon domain K07164 - - 0.0000004944 52.0
PYH2_k127_2992552_0 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.000000000000000000000000000000000000000000000001776 181.0
PYH2_k127_2992552_1 Receptor family ligand binding region K01999 - - 0.000000000000000000000000005025 124.0
PYH2_k127_3014014_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000002637 246.0
PYH2_k127_3014014_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000004622 196.0
PYH2_k127_3014014_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.00000000000000000000000000000000000000000000000001682 190.0
PYH2_k127_3014014_3 positive regulation of growth rate - - - 0.00000000000000000000000000000000000119 154.0
PYH2_k127_3014014_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.000000000000000000000000000000004621 135.0
PYH2_k127_3014014_5 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000001267 97.0
PYH2_k127_3014014_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000004718 91.0
PYH2_k127_3014014_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.000000000003488 68.0
PYH2_k127_3014014_8 Serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000000001718 75.0
PYH2_k127_3014014_9 PFAM response regulator receiver - - - 0.0003156 48.0
PYH2_k127_3023907_0 oligopeptide transport K03305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006422 537.0
PYH2_k127_3023907_1 regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 366.0
PYH2_k127_3023907_2 acid phosphatase activity - - - 0.00000000000000000000000000000000000000000000000000000001521 225.0
PYH2_k127_3023907_3 family UPF0029 - - - 0.000000000000000000062 93.0
PYH2_k127_3026118_0 Elongation factor G, domain IV K02355 - - 1.378e-201 651.0
PYH2_k127_3026118_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 577.0
PYH2_k127_3026118_10 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000003927 142.0
PYH2_k127_3026118_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K02573 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.000000000000000000000000000000001177 143.0
PYH2_k127_3026118_12 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000005772 140.0
PYH2_k127_3026118_13 DinB superfamily - - - 0.00000000000000000000000000000001612 135.0
PYH2_k127_3026118_14 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000002303 129.0
PYH2_k127_3026118_15 Cold shock protein K03704 - - 0.0000000000000000000000000003558 116.0
PYH2_k127_3026118_16 Outer membrane lipoprotein - - - 0.0000000000000000000000000005793 117.0
PYH2_k127_3026118_17 Smr domain - - - 0.00000000000000000000003043 106.0
PYH2_k127_3026118_18 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567,K07443 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0005488,GO:0005515,GO:0019899,GO:0097159,GO:1901363 2.1.1.63 0.000000000000000000003563 100.0
PYH2_k127_3026118_19 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000004952 75.0
PYH2_k127_3026118_2 ATP-dependent helicase activity K10844 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 411.0
PYH2_k127_3026118_20 - - - - 0.000000001929 64.0
PYH2_k127_3026118_3 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 353.0
PYH2_k127_3026118_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 GO:0003674,GO:0003824,GO:0008110,GO:0008483,GO:0016740,GO:0016769 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 339.0
PYH2_k127_3026118_5 recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 306.0
PYH2_k127_3026118_6 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 299.0
PYH2_k127_3026118_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000005752 226.0
PYH2_k127_3026118_8 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000002082 217.0
PYH2_k127_3026118_9 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000008356 145.0
PYH2_k127_3061491_0 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000007545 85.0
PYH2_k127_3080379_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 524.0
PYH2_k127_3080379_1 Peptidase M56 - - - 0.000000000002859 79.0
PYH2_k127_3080379_2 PFAM thioesterase superfamily - - - 0.00000000004302 63.0
PYH2_k127_3113415_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K18331 - 1.12.1.3 1.807e-252 796.0
PYH2_k127_3113415_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000005126 261.0
PYH2_k127_3130235_0 Angiotensin-converting enzyme K01283 - 3.4.15.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000428 542.0
PYH2_k127_3130235_1 glycosyl transferase, family 39 - - - 0.00000000000000000000000000009089 128.0
PYH2_k127_3130235_2 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000002287 66.0
PYH2_k127_3134593_0 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 489.0
PYH2_k127_3134593_1 PFAM Cytochrome c assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000003346 230.0
PYH2_k127_3134593_2 CcmB protein K02193,K02194 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0031224,GO:0031226,GO:0032991,GO:0042623,GO:0043190,GO:0044425,GO:0044459,GO:0044464,GO:0071944,GO:0098533,GO:0098796,GO:0098797,GO:1902494,GO:1902495,GO:1904949,GO:1990351 3.6.3.41 0.000000000000000000000000000000000000009305 155.0
PYH2_k127_3134593_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000001799 123.0
PYH2_k127_3134593_4 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000002727 105.0
PYH2_k127_3173795_0 amino acid - - - 2.603e-222 709.0
PYH2_k127_3173795_1 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 589.0
PYH2_k127_3173795_10 Putative regulatory protein - - - 0.000000000000000000000009156 112.0
PYH2_k127_3173795_11 - - - - 0.000000000000000006385 90.0
PYH2_k127_3173795_2 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 359.0
PYH2_k127_3173795_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 347.0
PYH2_k127_3173795_4 Tricorn protease C1 domain K08676 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 331.0
PYH2_k127_3173795_5 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000003525 238.0
PYH2_k127_3173795_6 involved in cell wall biogenesis - - - 0.000000000000000000000000000000000000000000000000000000001408 212.0
PYH2_k127_3173795_7 formate dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000001296 209.0
PYH2_k127_3173795_8 DEAD DEAH box helicase domain protein K06877 - - 0.0000000000000000000000000000000000000000000000000006198 192.0
PYH2_k127_3173795_9 This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis K01489 - 3.5.4.5 0.0000000000000000000000000000005474 126.0
PYH2_k127_3198265_0 PFAM Peptidase M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004958 279.0
PYH2_k127_3198265_1 GHMP kinases C terminal K07031 - 2.7.1.168 0.000000000000000000000000000000001519 142.0
PYH2_k127_3200293_0 - - - - 0.00000000000000000000000000000000000000000001829 172.0
PYH2_k127_3287282_0 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000002967 166.0
PYH2_k127_3287282_1 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000007382 147.0
PYH2_k127_3287282_2 Adenylosuccinate lyase K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006082,GO:0006106,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00001271 48.0
PYH2_k127_3396198_0 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 477.0
PYH2_k127_3396198_1 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000003933 179.0
PYH2_k127_3396198_2 Putative adhesin - - - 0.000000000000000000000000000000000000000000009181 174.0
PYH2_k127_3417991_0 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 302.0
PYH2_k127_3417991_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000001175 162.0
PYH2_k127_3444983_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002731 528.0
PYH2_k127_3444983_1 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000009327 202.0
PYH2_k127_3444983_2 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.00000000000000000000000000000000000003529 157.0
PYH2_k127_3473209_0 Recombinase - - - 3.775e-300 940.0
PYH2_k127_3473209_1 PFAM RNA-directed DNA polymerase (reverse transcriptase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003872 263.0
PYH2_k127_3473209_2 PFAM RNA-directed DNA polymerase (Reverse transcriptase) - - - 0.00000000000000000000000000000000000000000000000000000000000002264 224.0
PYH2_k127_3477900_0 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000001008 250.0
PYH2_k127_3493125_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004527,GO:0004532,GO:0004534,GO:0004540,GO:0005488,GO:0005515,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008409,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042802,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0090503,GO:0140098,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000003418 254.0
PYH2_k127_3493125_1 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.0000000000000000000000000001866 122.0
PYH2_k127_3594118_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 603.0
PYH2_k127_3594118_1 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 332.0
PYH2_k127_3594118_2 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001902 292.0
PYH2_k127_3594118_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000001449 193.0
PYH2_k127_3594118_4 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000499 172.0
PYH2_k127_359517_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 538.0
PYH2_k127_359517_1 ABC-type cobalt transport system ATPase component K16786,K16787 - - 0.00000000000000000000000000000000001335 149.0
PYH2_k127_364062_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 430.0
PYH2_k127_364062_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000002859 237.0
PYH2_k127_364062_2 Required for chromosome condensation and partitioning K03529 - - 0.000006704 49.0
PYH2_k127_364980_0 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000473 468.0
PYH2_k127_364980_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 290.0
PYH2_k127_364980_2 iron-nicotianamine transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007263 264.0
PYH2_k127_364980_3 Belongs to the ompA family - - - 0.000000000000000000000000000000000000003843 155.0
PYH2_k127_364980_4 cytochrome c biogenesis protein transmembrane region K06196 - - 0.000000000000000001789 96.0
PYH2_k127_364980_5 hyaluronan metabolic process - GO:0002526,GO:0002576,GO:0003674,GO:0004857,GO:0004866,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006810,GO:0006887,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0008150,GO:0009892,GO:0009987,GO:0010033,GO:0010466,GO:0010605,GO:0010951,GO:0012505,GO:0016020,GO:0016192,GO:0019222,GO:0030141,GO:0030162,GO:0030234,GO:0030414,GO:0031089,GO:0031323,GO:0031324,GO:0031410,GO:0031974,GO:0031982,GO:0031983,GO:0032268,GO:0032269,GO:0032940,GO:0034097,GO:0034774,GO:0042221,GO:0042827,GO:0043086,GO:0043226,GO:0043227,GO:0043229,GO:0043233,GO:0044092,GO:0044422,GO:0044424,GO:0044433,GO:0044444,GO:0044446,GO:0044464,GO:0045055,GO:0045861,GO:0046903,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051246,GO:0051248,GO:0051336,GO:0051346,GO:0052547,GO:0052548,GO:0060205,GO:0060255,GO:0061134,GO:0061135,GO:0065007,GO:0065009,GO:0070013,GO:0071944,GO:0080090,GO:0097708,GO:0098772,GO:0099503 - 0.000000002306 68.0
PYH2_k127_364980_6 Outer membrane protein beta-barrel domain - - - 0.00006877 53.0
PYH2_k127_3742205_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002019 261.0
PYH2_k127_3742205_1 Putative ATP-binding cassette - - - 0.0000000000000000000000000000000000000000000000000000000000000000002859 254.0
PYH2_k127_3742205_10 antisigma factor binding - - - 0.000005968 55.0
PYH2_k127_3742205_11 response regulator - - - 0.0003438 51.0
PYH2_k127_3742205_2 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000000000005696 219.0
PYH2_k127_3742205_3 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000001074 166.0
PYH2_k127_3742205_4 Surface antigen K07278 - - 0.00000000000000000000000000000001016 150.0
PYH2_k127_3742205_5 PFAM Class I peptide chain release factor K15034 - - 0.0000000000000000000000000000002692 129.0
PYH2_k127_3742205_6 PFAM transglutaminase domain protein - - - 0.000000000000000000000000004993 119.0
PYH2_k127_3742205_7 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000009585 85.0
PYH2_k127_3742205_8 photosystem II stabilization K02237,K02719 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0009521,GO:0009523,GO:0009579,GO:0016020,GO:0030075,GO:0030096,GO:0032991,GO:0034357,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044422,GO:0044424,GO:0044425,GO:0044436,GO:0044444,GO:0044459,GO:0044464,GO:0071944,GO:0098796,GO:0098797 - 0.000000000000003458 89.0
PYH2_k127_3742205_9 PFAM Tetratricopeptide repeat - - - 0.000004053 57.0
PYH2_k127_3743709_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 422.0
PYH2_k127_3743709_1 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000004765 164.0
PYH2_k127_3745001_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.365e-198 640.0
PYH2_k127_3745001_1 response regulator K02481,K07713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001521 428.0
PYH2_k127_3745001_2 GDP-mannose mannosyl hydrolase activity K00077,K01092,K03574 - 1.1.1.169,3.1.3.25,3.6.1.55 0.000000000000000000000000000000000000002422 152.0
PYH2_k127_3745472_0 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000006875 259.0
PYH2_k127_3745472_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005564 262.0
PYH2_k127_3745472_2 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000001497 185.0
PYH2_k127_3745472_3 Radical SAM superfamily - - - 0.0000000000000000000000000000000000002794 156.0
PYH2_k127_3745472_4 Protein of unknown function (DUF1295) - - - 0.000000000000000000000000000000000002496 145.0
PYH2_k127_3745472_5 - - - - 0.0000000000000000000000000001473 119.0
PYH2_k127_3745472_6 CoA binding domain K06929 - - 0.00000000000000000000000000106 117.0
PYH2_k127_3745472_7 Glycosyl transferase, family 2 - - - 0.000000000000000652 88.0
PYH2_k127_3745472_8 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000003293 58.0
PYH2_k127_3753149_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004408 301.0
PYH2_k127_3753149_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000001558 269.0
PYH2_k127_3753149_2 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000004125 235.0
PYH2_k127_3753149_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000008086 215.0
PYH2_k127_3753149_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000001007 151.0
PYH2_k127_3753149_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000217 130.0
PYH2_k127_3753149_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000005742 80.0
PYH2_k127_3753149_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000006068 75.0
PYH2_k127_3753149_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000976 57.0
PYH2_k127_3763091_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003365 286.0
PYH2_k127_3766459_0 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.000000000000000000000000000000000000000000000000000000000000001467 243.0
PYH2_k127_3766459_1 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000005362 198.0
PYH2_k127_3766459_10 RDD family - - - 0.000004451 57.0
PYH2_k127_3766459_2 PFAM MotA TolQ ExbB proton channel K03562 - - 0.00000000000000000000000000000000000000000000002767 177.0
PYH2_k127_3766459_3 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000007637 167.0
PYH2_k127_3766459_4 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000003866 147.0
PYH2_k127_3766459_5 PFAM OmpA MotB domain protein K03640 - - 0.000000000000000000000000000000001527 138.0
PYH2_k127_3766459_6 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000005923 138.0
PYH2_k127_3766459_7 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000009599 117.0
PYH2_k127_3766459_8 FHA domain - - - 0.00000000003682 73.0
PYH2_k127_3766459_9 TonB C terminal K03832 - - 0.000003531 59.0
PYH2_k127_3767117_0 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 426.0
PYH2_k127_3767117_1 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 425.0
PYH2_k127_3767117_2 phosphate transport system permease protein K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 353.0
PYH2_k127_377306_0 ABC transporter transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007274 401.0
PYH2_k127_377306_1 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000004311 121.0
PYH2_k127_377306_2 lysyltransferase activity K07027 - - 0.0000005568 59.0
PYH2_k127_3773589_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001413 508.0
PYH2_k127_3778529_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000001029 250.0
PYH2_k127_3778529_1 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000001242 111.0
PYH2_k127_3778529_2 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.000000000001069 73.0
PYH2_k127_3778529_3 Belongs to the bacterial ribosomal protein bL34 family K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000001429 68.0
PYH2_k127_3783989_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.832e-264 846.0
PYH2_k127_3783989_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 515.0
PYH2_k127_3783989_2 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 449.0
PYH2_k127_3783989_3 Psort location Cytoplasmic, score K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 364.0
PYH2_k127_3783989_4 PFAM Lytic transglycosylase catalytic K08309 - - 0.00000000000000000000000000000000000002591 153.0
PYH2_k127_3783989_5 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0000000000000000000000000001485 115.0
PYH2_k127_3783989_6 Peptidase family M28 - - - 0.000000000001625 79.0
PYH2_k127_3783989_7 Modulates RecA activity K03565 - - 0.00000009978 63.0
PYH2_k127_378439_0 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 285.0
PYH2_k127_378439_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000005177 112.0
PYH2_k127_3806032_0 MMPL family K03296 - - 0.0 1260.0
PYH2_k127_3806032_1 COG0346 Lactoylglutathione lyase and related lyases K15975 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 403.0
PYH2_k127_3806032_2 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 344.0
PYH2_k127_3806032_3 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009876 293.0
PYH2_k127_3806032_4 Dienelactone hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000003456 220.0
PYH2_k127_3806032_5 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000002942 193.0
PYH2_k127_3807526_0 ABC transporter, (ATP-binding protein) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 316.0
PYH2_k127_3807526_1 Insulinase (Peptidase family M16) - - - 0.000000000000000001136 88.0
PYH2_k127_3807526_2 ABC-2 family transporter protein K01992 - - 0.00001368 55.0
PYH2_k127_3808106_0 Alkaline phosphatase K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 488.0
PYH2_k127_3808106_1 Proton-conducting membrane transporter K12141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 377.0
PYH2_k127_3808106_2 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000003841 231.0
PYH2_k127_3808106_3 PhoQ Sensor K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000003262 204.0
PYH2_k127_3808106_4 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L - - - 0.000000000000000000000000000000000004357 148.0
PYH2_k127_3808106_5 cheY-homologous receiver domain K07658 - - 0.00000000000000000000000000894 121.0
PYH2_k127_3808106_6 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K12143,K15831 - - 0.000000000000000000000001062 104.0
PYH2_k127_3815289_0 of the beta-lactamase K00784 - 3.1.26.11 0.00000000000000000000000000000000000002779 154.0
PYH2_k127_3815289_1 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000000000001004 145.0
PYH2_k127_3815289_2 Sigma-70, region 4 K03088 - - 0.0000000000000009615 83.0
PYH2_k127_3820052_0 metallophosphoesterase K07096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004541 264.0
PYH2_k127_3820052_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000004267 220.0
PYH2_k127_3820097_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008255 282.0
PYH2_k127_3820097_1 PFAM Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000165 243.0
PYH2_k127_3820097_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000002844 224.0
PYH2_k127_3820097_3 - - - - 0.0000000000000000000000000000000000000000002725 168.0
PYH2_k127_3823307_0 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000003844 144.0
PYH2_k127_3823307_1 protein kinase activity - - - 0.00000000000007075 86.0
PYH2_k127_3823307_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000002863 62.0
PYH2_k127_3823307_3 sulfate adenylyltransferase K00958 - 2.7.7.4 0.0001691 49.0
PYH2_k127_3835044_0 Lipid A biosynthesis K02517 - 2.3.1.241 0.00000000000000000000000000000000000005422 155.0
PYH2_k127_3835044_1 PAP2 superfamily - - - 0.00000000000000000000000000000000007733 147.0
PYH2_k127_3835755_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 6.379e-295 933.0
PYH2_k127_3835755_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009292,GO:0009294,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030420,GO:0031668,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0044764,GO:0046483,GO:0050896,GO:0051704,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 486.0
PYH2_k127_3835755_10 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000001756 117.0
PYH2_k127_3835755_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000002428 96.0
PYH2_k127_3835755_12 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000007886 95.0
PYH2_k127_3835755_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 395.0
PYH2_k127_3835755_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 296.0
PYH2_k127_3835755_4 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003613 261.0
PYH2_k127_3835755_5 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000002331 235.0
PYH2_k127_3835755_6 AMP-binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000004833 213.0
PYH2_k127_3835755_7 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000009791 205.0
PYH2_k127_3835755_8 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000002363 177.0
PYH2_k127_3835755_9 PFAM response regulator receiver K07657 - - 0.00000000000000000000000001814 114.0
PYH2_k127_3845637_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 340.0
PYH2_k127_3845637_1 PFAM Mur ligase family, glutamate ligase domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000002325 227.0
PYH2_k127_3845637_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000006749 197.0
PYH2_k127_3845637_3 ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000031 111.0
PYH2_k127_3853286_0 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 377.0
PYH2_k127_3853286_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000006159 71.0
PYH2_k127_3859096_0 Peptidase m28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 614.0
PYH2_k127_3859096_1 diguanylate cyclase - - - 0.00000005882 61.0
PYH2_k127_3860198_0 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.00000000000000000000000000000000000000000000000000000000006682 212.0
PYH2_k127_3860198_1 Conserved hypothetical protein 95 - - - 0.000000000000000001753 94.0
PYH2_k127_3873837_0 DinB family - - - 0.0000000000000000000000000000000000000000002454 169.0
PYH2_k127_3873837_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000008063 117.0
PYH2_k127_3873837_2 formate dehydrogenase K00127 - - 0.00000000000000003442 94.0
PYH2_k127_3874174_0 Tricorn protease homolog - - - 0.0 1088.0
PYH2_k127_3892416_0 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000002733 154.0
PYH2_k127_3892416_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0001088 53.0
PYH2_k127_3893191_0 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000004943 183.0
PYH2_k127_3893191_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585,K07799 - - 0.0000000008183 68.0
PYH2_k127_3905496_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 312.0
PYH2_k127_3905496_1 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000005558 216.0
PYH2_k127_3905496_2 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs - - - 0.00000000000000000000000000000000000000000000000003463 192.0
PYH2_k127_3905496_3 Putative esterase K07017 - - 0.000000000000000000000000003711 119.0
PYH2_k127_3918012_0 Proton-conducting membrane transporter K12137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 476.0
PYH2_k127_3918012_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K12139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 418.0
PYH2_k127_3918012_2 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 301.0
PYH2_k127_3918012_3 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000003463 221.0
PYH2_k127_3918012_4 Nickel-dependent hydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000009956 212.0
PYH2_k127_3918012_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.000000000000000000000000000000001886 139.0
PYH2_k127_3918012_6 Hydrogenase maturation protease K08315 - 3.4.23.51 0.0000000000000000000000000547 114.0
PYH2_k127_3926544_0 - - - - 0.0000000000000001494 93.0
PYH2_k127_3926544_1 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000007543 83.0
PYH2_k127_3926544_3 Putative adhesin - - - 0.000001469 60.0
PYH2_k127_3941006_0 Ras family - - - 0.000000000000000000000000000000000000000000000000000000000006235 233.0
PYH2_k127_3941006_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000002332 192.0
PYH2_k127_3941006_2 cheY-homologous receiver domain - - - 0.00000000000000000000000000000004617 130.0
PYH2_k127_3941006_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000668 132.0
PYH2_k127_3942493_0 CAAX protease self-immunity K07052 - - 0.0000000000000000002491 99.0
PYH2_k127_3947970_0 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 475.0
PYH2_k127_3947970_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 437.0
PYH2_k127_3947970_10 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000006553 128.0
PYH2_k127_3947970_11 - - - - 0.0000000000000000000001629 106.0
PYH2_k127_3947970_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 387.0
PYH2_k127_3947970_3 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds K01459,K01501,K11206,K13566 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0030312,GO:0044464,GO:0050152,GO:0071944,GO:0106008 3.5.1.3,3.5.1.77,3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009455 333.0
PYH2_k127_3947970_4 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 308.0
PYH2_k127_3947970_5 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 293.0
PYH2_k127_3947970_6 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003967 282.0
PYH2_k127_3947970_7 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000003095 188.0
PYH2_k127_3947970_8 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000004582 161.0
PYH2_k127_3947970_9 phosphatidate cytidylyltransferase activity K00981 - 2.7.7.41 0.00000000000000000000000000000001357 144.0
PYH2_k127_3949817_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 1.521e-221 709.0
PYH2_k127_3949817_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 350.0
PYH2_k127_3956202_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 5.954e-267 851.0
PYH2_k127_3956202_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 354.0
PYH2_k127_3956202_2 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 321.0
PYH2_k127_3956202_3 Ribosomal protein S1 K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006928 273.0
PYH2_k127_3956202_4 histidine kinase HAMP region domain protein K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000269 236.0
PYH2_k127_3956202_5 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000001964 201.0
PYH2_k127_3956202_6 PFAM response regulator receiver K02483,K07658,K07668 - - 0.0000000000000000000000000000000000000000000000009144 186.0
PYH2_k127_3956202_8 pfam chad - - - 0.0000001333 61.0
PYH2_k127_3956202_9 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000002178 49.0
PYH2_k127_3958550_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 1.648e-235 739.0
PYH2_k127_3958550_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 578.0
PYH2_k127_3958550_10 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 295.0
PYH2_k127_3958550_11 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) K02823 - - 0.000000000000000000000000000000000000000000000009 182.0
PYH2_k127_3958550_12 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000003722 116.0
PYH2_k127_3958550_13 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000004835 82.0
PYH2_k127_3958550_2 tagaturonate epimerase K21619 - 5.1.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 524.0
PYH2_k127_3958550_3 lactate racemase activity K22373 - 5.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 507.0
PYH2_k127_3958550_4 Dehydrogenase K00248,K00249,K20035 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016627,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050660,GO:0050662,GO:0052890,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.3.8.1,1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004338 499.0
PYH2_k127_3958550_5 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 389.0
PYH2_k127_3958550_6 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 361.0
PYH2_k127_3958550_7 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 357.0
PYH2_k127_3958550_8 Catalyzes the conversion of dihydroorotate to orotate K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 340.0
PYH2_k127_3958550_9 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 301.0
PYH2_k127_3968177_0 Domain of unknown function (DUF1972) K12996 - - 0.0000000000000000000000000000000000000000000000000000000000000006505 232.0
PYH2_k127_3968177_1 Glycosyl transferase, family 2 K07011 - - 0.000000000000000000000000000000000000000000000000000001648 204.0
PYH2_k127_3972311_0 ATP-binding region, ATPase domain protein domain protein - - - 0.000000000000000000000000000000000000000005715 162.0
PYH2_k127_3993095_0 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000001163 201.0
PYH2_k127_3993095_1 MOSC N-terminal beta barrel domain K07140 - - 0.0000006466 52.0
PYH2_k127_3993095_2 Domain of unknown function (DUF4177) - - - 0.000004204 52.0
PYH2_k127_4022486_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 368.0
PYH2_k127_4022486_1 indolepyruvate ferredoxin oxidoreductase beta subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000037 190.0
PYH2_k127_4022486_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.0000000000000000000000000000001145 124.0
PYH2_k127_4026439_0 glucosamine-1-phosphate N-acetyltransferase activity K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000005083 192.0
PYH2_k127_4026439_1 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.0000000000000000000000000000000000009332 157.0
PYH2_k127_4026439_2 domain, Protein - - - 0.0000000000000000000000000000000009679 150.0
PYH2_k127_4026439_3 Tetratricopeptide repeat - - - 0.000000000000000000002607 108.0
PYH2_k127_4026439_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000001759 98.0
PYH2_k127_4027480_0 AMP-binding enzyme - - - 1.419e-212 674.0
PYH2_k127_4085645_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain K01840 - 5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 438.0
PYH2_k127_4085645_1 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000003134 206.0
PYH2_k127_4085645_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000001745 150.0
PYH2_k127_4085645_3 THUMP K07444,K12297 - 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000004841 140.0
PYH2_k127_4122564_0 lysine 2,3-aminomutase activity K01843 - 5.4.3.2 3.396e-195 614.0
PYH2_k127_4122564_1 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 551.0
PYH2_k127_4122564_10 Membrane protein involved in the export of O-antigen and teichoic acid - - - 0.000000000003197 78.0
PYH2_k127_4122564_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 438.0
PYH2_k127_4122564_3 Transketolase, thiamine diphosphate binding domain K00163 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001265 268.0
PYH2_k127_4122564_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000009052 224.0
PYH2_k127_4122564_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000002763 166.0
PYH2_k127_4122564_6 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000001337 149.0
PYH2_k127_4122564_7 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000001975 140.0
PYH2_k127_4122564_8 Glycosyl transferase, family 2 - - - 0.0000000000000000000000000000002885 135.0
PYH2_k127_4122564_9 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000005905 136.0
PYH2_k127_4163133_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 281.0
PYH2_k127_4163133_1 recA bacterial DNA recombination protein - - - 0.000000000000000000000004834 109.0
PYH2_k127_4163133_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 GO:0001530,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006869,GO:0008150,GO:0008289,GO:0009279,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016043,GO:0019867,GO:0022607,GO:0030312,GO:0030313,GO:0031975,GO:0033036,GO:0043163,GO:0043165,GO:0044085,GO:0044091,GO:0044462,GO:0044464,GO:0045229,GO:0051179,GO:0051234,GO:0061024,GO:0071702,GO:0071709,GO:0071840,GO:0071944,GO:0097367,GO:1901264 - 0.000000000000000000001703 108.0
PYH2_k127_4163133_3 Peptidase S24-like - - - 0.000005453 57.0
PYH2_k127_4163133_4 Helix-turn-helix XRE-family like proteins - - - 0.00001716 56.0
PYH2_k127_4169565_0 Cytidylyltransferase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 517.0
PYH2_k127_4169565_1 dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000008633 128.0
PYH2_k127_4207294_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000004204 185.0
PYH2_k127_4207294_1 Histidine kinase - - - 0.0000000000000000002308 103.0
PYH2_k127_4207294_2 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000003371 102.0
PYH2_k127_4207294_3 GlcNAc-PI de-N-acetylase - - - 0.0005221 45.0
PYH2_k127_4207294_4 PFAM PEGA domain - - - 0.0006154 51.0
PYH2_k127_424419_0 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 541.0
PYH2_k127_424419_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 297.0
PYH2_k127_424419_2 HEAT repeats - - - 0.00000000002466 77.0
PYH2_k127_424419_3 SMART Metal-dependent phosphohydrolase, HD region - - - 0.0000000004139 72.0
PYH2_k127_4307293_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 591.0
PYH2_k127_4307293_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000008005 211.0
PYH2_k127_4307293_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0017076,GO:0030234,GO:0030554,GO:0036094,GO:0044424,GO:0044444,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363 - 0.00000000000000000000000000000001392 134.0
PYH2_k127_4307293_3 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000002787 116.0
PYH2_k127_4309728_0 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000098 458.0
PYH2_k127_4309728_1 ArgK protein K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000006242 248.0
PYH2_k127_4309728_2 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000004136 160.0
PYH2_k127_4309728_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K15396 - 2.1.1.200 0.00000000000000000000000000003279 125.0
PYH2_k127_4309728_4 - - - - 0.0000000000000005587 87.0
PYH2_k127_4309728_5 Stage II sporulation D domain protein K06381 - - 0.00000000002664 64.0
PYH2_k127_4359225_0 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001688 278.0
PYH2_k127_4359225_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016075,GO:0016787,GO:0016788,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0034470,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043170,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000001335 269.0
PYH2_k127_4359225_10 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00005191 55.0
PYH2_k127_4359225_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000004257 219.0
PYH2_k127_4359225_3 Ami_3 K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000001715 188.0
PYH2_k127_4359225_4 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.00000000000000000000000000000000297 138.0
PYH2_k127_4359225_5 Lipoate-protein ligase - - - 0.00000000000000000000000000000004728 134.0
PYH2_k127_4359225_6 Sporulation and spore germination - - - 0.000000000000002381 84.0
PYH2_k127_4359225_7 lyase activity - - - 0.000000000009878 74.0
PYH2_k127_4359225_9 - - - - 0.000002599 50.0
PYH2_k127_440748_0 Belongs to the ClpA ClpB family K03696 - - 1.347e-261 832.0
PYH2_k127_440748_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 530.0
PYH2_k127_440748_10 Protein tyrosine kinase K12132 - 2.7.11.1 0.0008703 43.0
PYH2_k127_440748_2 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006738 461.0
PYH2_k127_440748_3 Surface antigen variable number K07277 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 352.0
PYH2_k127_440748_4 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000008361 260.0
PYH2_k127_440748_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002485 251.0
PYH2_k127_440748_6 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000003382 118.0
PYH2_k127_440748_7 Vitamin K epoxide reductase family - - - 0.00000000000000006197 85.0
PYH2_k127_440748_8 membrane K07058 - - 0.00000000000001347 86.0
PYH2_k127_440748_9 Putative prokaryotic signal transducing protein - - - 0.0000004439 56.0
PYH2_k127_4624803_0 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000004481 133.0
PYH2_k127_4624803_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000002473 66.0
PYH2_k127_4634612_0 YmdB-like protein K02029,K02030,K09769 GO:0003674,GO:0003824,GO:0004112,GO:0004113,GO:0008081,GO:0016787,GO:0016788,GO:0042578 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002675 287.0
PYH2_k127_4634612_1 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00000000000000000000000000000000000000000000001151 188.0
PYH2_k127_4634612_2 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000005171 158.0
PYH2_k127_4634612_3 PFAM Cyclic nucleotide-binding K01420,K21563 - - 0.0000000000000000000000000000000002588 144.0
PYH2_k127_4675656_0 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001035 203.0
PYH2_k127_4675656_1 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.000000000000000000000000000000000000000000000000000001616 197.0
PYH2_k127_4675656_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000001434 139.0
PYH2_k127_4675656_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000002725 81.0
PYH2_k127_4675656_4 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00002828 54.0
PYH2_k127_4679686_0 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000001358 264.0
PYH2_k127_4679686_1 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000001071 175.0
PYH2_k127_4679686_2 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000002188 152.0
PYH2_k127_4679686_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 GO:0006629,GO:0006644,GO:0006650,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009987,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0045017,GO:0046474,GO:0046486,GO:0071704,GO:0090407,GO:1901576 2.7.8.41 0.000000000000000000000000006754 121.0
PYH2_k127_4679686_4 AI-2E family transporter - - - 0.0000000000005106 77.0
PYH2_k127_4679686_5 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.000000000002988 70.0
PYH2_k127_4685141_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 465.0
PYH2_k127_4685141_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 347.0
PYH2_k127_4685141_2 Glycosyl transferase, family 2 - GO:0003674,GO:0003824,GO:0016740,GO:0016757 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002334 289.0
PYH2_k127_4685141_3 COG1134 ABC-type polysaccharide polyol phosphate transport system, ATPase component K09691 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002456 271.0
PYH2_k127_4685141_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000002935 223.0
PYH2_k127_4685141_5 ATP-grasp domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000006077 226.0
PYH2_k127_4685141_6 phosphoheptose isomerase K01101,K02566 - 3.1.3.41 0.000000000000000000000000000023 129.0
PYH2_k127_4685141_7 Hypothetical methyltransferase - - - 0.000000000000000006499 94.0
PYH2_k127_4693380_0 von Willebrand factor, type A K07114 - - 8.103e-269 849.0
PYH2_k127_4693380_1 GMC oxidoreductase K03333 - 1.1.3.6 2.984e-194 623.0
PYH2_k127_4693380_2 PFAM membrane protein of K08972 - - 0.00000000000000000000003837 103.0
PYH2_k127_4693380_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000003907 108.0
PYH2_k127_4694564_0 FAD linked oxidase - - - 3.141e-198 632.0
PYH2_k127_4694564_1 Belongs to the glycosyl hydrolase 13 family - - - 0.00000000000001291 75.0
PYH2_k127_4711499_0 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 532.0
PYH2_k127_4711499_1 mitochondrial electron transport, ubiquinol to cytochrome c K01412,K07263,K17732 GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005746,GO:0005750,GO:0005759,GO:0006091,GO:0006119,GO:0006122,GO:0006139,GO:0006163,GO:0006508,GO:0006605,GO:0006626,GO:0006627,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006839,GO:0006886,GO:0006996,GO:0007005,GO:0007154,GO:0007165,GO:0008104,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009060,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015980,GO:0016020,GO:0016043,GO:0016310,GO:0016485,GO:0016787,GO:0017087,GO:0017144,GO:0019538,GO:0019637,GO:0019693,GO:0019866,GO:0022900,GO:0022904,GO:0023052,GO:0031090,GO:0031930,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0031982,GO:0032991,GO:0033036,GO:0033365,GO:0034613,GO:0034641,GO:0034982,GO:0042773,GO:0042775,GO:0042886,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0045184,GO:0045275,GO:0045333,GO:0046034,GO:0046483,GO:0046872,GO:0046907,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051179,GO:0051234,GO:0051604,GO:0051641,GO:0051649,GO:0051716,GO:0055086,GO:0055114,GO:0065007,GO:0070011,GO:0070013,GO:0070069,GO:0070469,GO:0070585,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072521,GO:0072594,GO:0072655,GO:0098796,GO:0098798,GO:0098800,GO:0098803,GO:0140096,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 3.4.24.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 390.0
PYH2_k127_4711499_2 TonB dependent receptor K02014 - - 0.0000000478 61.0
PYH2_k127_4711499_3 Polymer-forming cytoskeletal - - - 0.0000002565 58.0
PYH2_k127_4711499_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000008195 57.0
PYH2_k127_4711499_5 energy transducer activity K03832 - - 0.0002177 44.0
PYH2_k127_4711499_6 Putative adhesin - - - 0.0006795 51.0
PYH2_k127_4713991_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.759e-219 701.0
PYH2_k127_4713991_1 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 317.0
PYH2_k127_4713991_2 Pilus assembly protein, PilO K02664 - - 0.00000000000000000003008 98.0
PYH2_k127_4713991_3 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000003022 92.0
PYH2_k127_4713991_4 PFAM Fimbrial assembly family protein K02663 - - 0.00000000000001031 82.0
PYH2_k127_4713991_6 type IV pilus secretin PilQ K02666 - - 0.00002286 55.0
PYH2_k127_4717250_0 belongs to the aldehyde dehydrogenase family - - - 0.00000000000008317 76.0
PYH2_k127_4717250_1 - - - - 0.000000000003266 78.0
PYH2_k127_4718284_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1294.0
PYH2_k127_4718284_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 342.0
PYH2_k127_4718284_2 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000006338 173.0
PYH2_k127_4718284_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000009036 62.0
PYH2_k127_4720339_0 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 294.0
PYH2_k127_4720339_1 VIT family - - - 0.000000000000000000000000000000000000000004003 161.0
PYH2_k127_4720771_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 355.0
PYH2_k127_4720771_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 320.0
PYH2_k127_4720771_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 317.0
PYH2_k127_4720771_3 PFAM natural resistance-associated macrophage protein K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005169 266.0
PYH2_k127_4720771_4 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000007434 265.0
PYH2_k127_4720771_5 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000001718 101.0
PYH2_k127_4720771_6 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000003612 88.0
PYH2_k127_4726692_0 cellulose binding - - - 0.0 1291.0
PYH2_k127_4726692_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 451.0
PYH2_k127_4726692_10 Ankyrin repeat - - - 0.00000000000000000000000000000000000000007707 161.0
PYH2_k127_4726692_2 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000842 452.0
PYH2_k127_4726692_3 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 400.0
PYH2_k127_4726692_4 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 389.0
PYH2_k127_4726692_5 Glycosyl transferase family 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 351.0
PYH2_k127_4726692_6 His Kinase A (phosphoacceptor) domain K13598 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005122 298.0
PYH2_k127_4726692_7 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000001113 252.0
PYH2_k127_4726692_8 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.00000000000000000000000000000000000000000000008077 173.0
PYH2_k127_4726692_9 HD domain - - - 0.0000000000000000000000000000000000000000004294 179.0
PYH2_k127_4740642_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 6.87e-262 820.0
PYH2_k127_4740642_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000025 399.0
PYH2_k127_4740642_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000001251 229.0
PYH2_k127_4740642_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000006467 205.0
PYH2_k127_4743786_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 2.903e-247 777.0
PYH2_k127_4743786_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 524.0
PYH2_k127_4743786_10 histidine kinase A domain protein - - - 0.000000000000002537 82.0
PYH2_k127_4743786_11 Zn peptidase - - - 0.0000000000009757 80.0
PYH2_k127_4743786_12 DNA binding - GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010313,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048027,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0090305,GO:0097159,GO:1901360,GO:1901363,GO:2000112,GO:2000113 - 0.0008146 43.0
PYH2_k127_4743786_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835,K01840 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 362.0
PYH2_k127_4743786_3 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000001052 276.0
PYH2_k127_4743786_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000003454 220.0
PYH2_k127_4743786_5 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000004895 194.0
PYH2_k127_4743786_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000002482 173.0
PYH2_k127_4743786_7 STAS domain K04749 - - 0.00000000000000000000000000000006662 128.0
PYH2_k127_4743786_8 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.00000000000000000000000008037 117.0
PYH2_k127_4743786_9 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.000000000000000000000001623 111.0
PYH2_k127_4745900_0 tagaturonate epimerase K21619 - 5.1.2.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 412.0
PYH2_k127_4745900_1 TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 297.0
PYH2_k127_4745900_2 Creatinine amidohydrolase K01470,K22232 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000003406 231.0
PYH2_k127_4749975_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000126 266.0
PYH2_k127_4749975_1 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000002471 145.0
PYH2_k127_4752223_0 butyrate kinase activity K00625,K00929,K04020,K13788 GO:0003674,GO:0003824,GO:0006950,GO:0008150,GO:0008959,GO:0009266,GO:0009408,GO:0009628,GO:0016407,GO:0016740,GO:0016746,GO:0016747,GO:0050896 2.3.1.8,2.7.2.7 7.4e-323 1005.0
PYH2_k127_4752223_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 1.509e-197 631.0
PYH2_k127_4752223_10 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000002481 111.0
PYH2_k127_4752223_11 Rubrerythrin - - - 0.0000003315 56.0
PYH2_k127_4752223_12 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000001848 57.0
PYH2_k127_4752223_13 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00002869 54.0
PYH2_k127_4752223_2 7TM-HD extracellular K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008508 393.0
PYH2_k127_4752223_3 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 344.0
PYH2_k127_4752223_4 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 347.0
PYH2_k127_4752223_5 Phosphate acetyl/butaryl transferase K00634,K13788 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 313.0
PYH2_k127_4752223_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000003509 242.0
PYH2_k127_4752223_7 Transporter associated domain K06189 - - 0.000000000000000000000000000000000000000000000000007736 200.0
PYH2_k127_4752223_8 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000001625 173.0
PYH2_k127_4752223_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000001307 114.0
PYH2_k127_4756866_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 4.216e-197 637.0
PYH2_k127_4756866_1 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000000000000000000000003006 145.0
PYH2_k127_4756866_2 Domain of unknown function (DUF2088) - - - 0.0000000000000000000000000000007607 132.0
PYH2_k127_4756866_3 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000004688 100.0
PYH2_k127_476313_0 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 4.31e-220 696.0
PYH2_k127_476313_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 442.0
PYH2_k127_476313_2 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000003439 238.0
PYH2_k127_476313_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000003082 164.0
PYH2_k127_476313_4 HIT domain K02503 - - 0.0000000000000000000000000000000000002153 153.0
PYH2_k127_476313_5 Belongs to the 5'-nucleotidase family K01119,K11751 - 3.1.3.5,3.1.3.6,3.1.4.16,3.6.1.45 0.000000000003227 74.0
PYH2_k127_476313_6 Belongs to the UPF0248 family K09715 - - 0.000013 57.0
PYH2_k127_4778810_0 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 593.0
PYH2_k127_4778810_1 prohibitin homologues K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005249 403.0
PYH2_k127_4790190_0 Catalyzes the oxidation of malonate semialdehyde (MSA) and methylmalonate semialdehyde (MMSA) into acetyl-CoA and propanoyl-CoA, respectively K00131 - 1.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 518.0
PYH2_k127_4790190_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005603 274.0
PYH2_k127_4790190_2 PFAM peptidase - - - 0.0000000000000000000000000000000000001662 157.0
PYH2_k127_4803673_0 SPTR Transposase IS4 family - - - 0.0000000000000000001767 102.0
PYH2_k127_4814937_0 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 418.0
PYH2_k127_4814937_1 Bacterial membrane protein YfhO - - - 0.000000000001109 71.0
PYH2_k127_4817628_0 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000002519 228.0
PYH2_k127_4817628_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.000000000000000000000000000000000000000000000000000000002015 212.0
PYH2_k127_4817628_2 Protein of unknown function (DUF3179) - - - 0.00000000000000000000000000000000000000001484 177.0
PYH2_k127_4817628_3 Cytochrome oxidase assembly protein K02259,K03110 - - 0.00000000000000000000000000000000000007388 160.0
PYH2_k127_4817628_4 Mechanosensitive ion channel - - - 0.00000000000007641 80.0
PYH2_k127_4843942_0 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 446.0
PYH2_k127_4843942_1 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000000000000000000002002 220.0
PYH2_k127_4843942_2 Peptidase family M20/M25/M40 - - - 0.00000002256 63.0
PYH2_k127_4848587_0 GMC oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 310.0
PYH2_k127_4848587_1 PFAM Thymidine kinase K00857 - 2.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000769 224.0
PYH2_k127_4848587_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000004825 64.0
PYH2_k127_4848587_3 GMC oxidoreductase - - - 0.0001508 50.0
PYH2_k127_4852217_0 Asp/Glu/Hydantoin racemase K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000119 255.0
PYH2_k127_4852217_1 Peptidase family S58 K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000002839 253.0
PYH2_k127_4852217_2 Domain of unknown function (DUF4442) - - - 0.00000000000000000000000000000000000000000000001607 177.0
PYH2_k127_4852217_3 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000001271 137.0
PYH2_k127_4857701_0 phosphate transport system permease protein K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 488.0
PYH2_k127_4857701_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
PYH2_k127_4862250_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 349.0
PYH2_k127_4862250_1 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003923 282.0
PYH2_k127_489801_0 amino acid K03294 - - 6.303e-258 804.0
PYH2_k127_489801_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000001427 222.0
PYH2_k127_489801_2 aminopeptidase activity K19689 - - 0.000000000000000000000000000000000000000000000001278 194.0
PYH2_k127_489801_3 tRNA pseudouridine synthase K06173 - 5.4.99.12 0.0000000000000000000000000000000005407 138.0
PYH2_k127_4912525_0 TIGRFAM 2-oxoglutarate dehydrogenase, E1 K00164,K01616 - 1.2.4.2,4.1.1.71 1.684e-204 651.0
PYH2_k127_4912525_1 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000000000000000001147 161.0
PYH2_k127_4912525_2 PAP2 superfamily - - - 0.000000001795 67.0
PYH2_k127_4924097_0 DEAD-like helicases superfamily K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 526.0
PYH2_k127_4924097_1 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 512.0
PYH2_k127_4924097_2 PFAM Metallophosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 380.0
PYH2_k127_4924097_3 Putative serine dehydratase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001526 289.0
PYH2_k127_4924097_4 COG1807 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003457 261.0
PYH2_k127_4924097_5 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000002438 155.0
PYH2_k127_4924097_6 RNA recognition motif - - - 0.000000000000000000001565 98.0
PYH2_k127_4924097_7 RNA recognition motif - - - 0.00000000000003936 75.0
PYH2_k127_4924097_8 Belongs to the UPF0761 family K07058 - - 0.00003328 55.0
PYH2_k127_4975530_0 aconitate hydratase K01681 - 4.2.1.3 1.221e-286 896.0
PYH2_k127_4975530_1 PFAM CBS domain containing protein K07168 - - 0.00000000000000000000001056 106.0
PYH2_k127_4983645_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 8.296e-212 685.0
PYH2_k127_4983645_1 - - - - 0.00000000000000000000000000176 129.0
PYH2_k127_4983645_2 - - - - 0.000000000000000000000007415 109.0
PYH2_k127_4983645_3 histidine kinase A domain protein - - - 0.00000000000138 74.0
PYH2_k127_4983645_4 response regulator K20977 - - 0.000000000001478 73.0
PYH2_k127_4989599_0 GMP synthase C terminal domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 526.0
PYH2_k127_4989599_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000001977 164.0
PYH2_k127_5008808_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 5.709e-223 711.0
PYH2_k127_5026942_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 357.0
PYH2_k127_5026942_1 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 346.0
PYH2_k127_5026942_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 299.0
PYH2_k127_5026942_3 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 310.0
PYH2_k127_5026942_4 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 299.0
PYH2_k127_5026942_5 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000005019 257.0
PYH2_k127_5026942_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000002099 224.0
PYH2_k127_5026942_7 Histidine kinase - - - 0.0000000000000000000000000000002155 143.0
PYH2_k127_5026942_8 Glycosyl transferase, family 2 K20444 - - 0.00000000000000000000000000003357 126.0
PYH2_k127_5026942_9 Tetratricopeptide TPR_2 repeat protein - - - 0.0000002658 62.0
PYH2_k127_5039708_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 3.5e-251 794.0
PYH2_k127_5039708_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000008663 192.0
PYH2_k127_5040986_0 Polysaccharide export protein K01991,K20988 - - 0.0000000000000000000000000000000000000000000000000000000000000006876 230.0
PYH2_k127_5040986_1 G-rich domain on putative tyrosine kinase K16554 - - 0.0000000000000317 81.0
PYH2_k127_5073099_0 PFAM Uncharacterised conserved protein UCP033563 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 490.0
PYH2_k127_5073099_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 365.0
PYH2_k127_5085299_0 Cell shape determining protein MreB Mrl K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 307.0
PYH2_k127_5085299_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006603 299.0
PYH2_k127_5085299_2 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000004163 181.0
PYH2_k127_5099324_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000001929 263.0
PYH2_k127_5099324_1 ATPases associated with a variety of cellular activities K16786,K16787 - - 0.0000000003441 64.0
PYH2_k127_5099324_2 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.000001891 58.0
PYH2_k127_5099324_3 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00004134 56.0
PYH2_k127_5133586_0 KR domain K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.000000000000000000000000000000000000000000000000000000005868 207.0
PYH2_k127_5133586_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000867 185.0
PYH2_k127_5133586_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000008656 151.0
PYH2_k127_5133586_3 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000004255 102.0
PYH2_k127_5133586_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000986 106.0
PYH2_k127_5133586_5 geranylgeranyl reductase K10960 - 1.3.1.111,1.3.1.83 0.000007924 51.0
PYH2_k127_5180282_0 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 396.0
PYH2_k127_5180282_1 Histidine kinase K07683 - 2.7.13.3 0.00000000000000000000000000000000000000000008619 182.0
PYH2_k127_5180282_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000007515 91.0
PYH2_k127_5193002_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.355e-283 893.0
PYH2_k127_5193002_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.483e-268 851.0
PYH2_k127_5193002_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 289.0
PYH2_k127_5193002_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000005507 250.0
PYH2_k127_5193002_4 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000000000002196 155.0
PYH2_k127_5209219_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007778 498.0
PYH2_k127_5209219_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 334.0
PYH2_k127_5209219_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 324.0
PYH2_k127_5209219_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000001726 86.0
PYH2_k127_5209219_4 nuclear chromosome segregation - - - 0.00000000002352 76.0
PYH2_k127_5283405_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006895 581.0
PYH2_k127_5283405_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000005569 260.0
PYH2_k127_5283405_2 Squalene--hopene cyclase - - - 0.00000000000000000000000000000000000000001341 159.0
PYH2_k127_5283405_3 Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000004372 141.0
PYH2_k127_5300572_0 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 386.0
PYH2_k127_5300572_1 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000002986 164.0
PYH2_k127_5300572_2 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000003457 121.0
PYH2_k127_535778_0 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 461.0
PYH2_k127_535778_1 Homeodomain-like domain K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007144 367.0
PYH2_k127_535778_2 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 310.0
PYH2_k127_535778_3 Putative carbohydrate binding domain K00702 - 2.4.1.20 0.00000000000000000002389 92.0
PYH2_k127_5381869_0 Formiminotransferase-cyclodeaminase K00603,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003565 529.0
PYH2_k127_5381869_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000001787 169.0
PYH2_k127_5606725_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 6.836e-279 884.0
PYH2_k127_5606725_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 316.0
PYH2_k127_5606725_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004883 286.0
PYH2_k127_5606725_3 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000001447 243.0
PYH2_k127_5606725_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000001005 251.0
PYH2_k127_5606725_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.000000000000000000000000000000000000001351 162.0
PYH2_k127_5606725_6 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.00000000000000000000004448 109.0
PYH2_k127_5606725_7 Protein of unknown function (DUF2914) - - - 0.000000000000291 78.0
PYH2_k127_5606725_8 outer membrane autotransporter barrel domain protein - - - 0.00000000001841 73.0
PYH2_k127_5607973_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 592.0
PYH2_k127_5607973_1 Fe-S cluster assembly K07033,K09015 - - 0.000000002808 66.0
PYH2_k127_5617399_0 PFAM Alpha beta hydrolase K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 376.0
PYH2_k127_5617399_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000223 171.0
PYH2_k127_5617399_2 von Willebrand factor, type A - - - 0.00000000000000000000000000000000004484 156.0
PYH2_k127_5617399_3 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 0.00000000000000000000000000001092 120.0
PYH2_k127_5617399_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000004834 109.0
PYH2_k127_5617399_5 Tetratricopeptide repeat K20543 - - 0.0000000000001329 85.0
PYH2_k127_5619494_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 611.0
PYH2_k127_5619781_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 466.0
PYH2_k127_5620045_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000126 259.0
PYH2_k127_5621444_0 Uncharacterized membrane protein (DUF2298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 646.0
PYH2_k127_5621444_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 511.0
PYH2_k127_5621444_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000004674 236.0
PYH2_k127_5621444_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000002089 217.0
PYH2_k127_5621444_4 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000007123 203.0
PYH2_k127_5621444_5 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000001111 186.0
PYH2_k127_5621444_6 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000002079 165.0
PYH2_k127_5621444_7 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000077 80.0
PYH2_k127_5621628_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 292.0
PYH2_k127_5621628_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 285.0
PYH2_k127_5621628_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000002485 191.0
PYH2_k127_5621628_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000007736 177.0
PYH2_k127_5621628_4 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000009626 143.0
PYH2_k127_5621628_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.00000000000000000000000000000002513 126.0
PYH2_k127_5621628_6 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000501 127.0
PYH2_k127_5621628_7 Regulatory protein ArsR - - - 0.00000000000000000002464 98.0
PYH2_k127_5621628_8 Ribosomal protein L36 K02919 - - 0.0000000000003391 70.0
PYH2_k127_5621879_0 Molybdopterin oxidoreductase, iron-sulfur binding subunit K00184 - - 1.715e-230 734.0
PYH2_k127_5621879_1 Polysulphide reductase K00185 - - 4.525e-220 697.0
PYH2_k127_5621879_2 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000001438 207.0
PYH2_k127_5621879_3 Protein of unknown function (DUF3341) - - - 0.000000000000000000000000000000000000000000000000006351 190.0
PYH2_k127_5627125_0 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 309.0
PYH2_k127_5627125_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000363 239.0
PYH2_k127_5627125_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000002394 230.0
PYH2_k127_5627125_3 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000108 140.0
PYH2_k127_5627125_4 Protein of unknown function (DUF1015) K00262 - 1.4.1.4 0.000000000000000000008757 97.0
PYH2_k127_5627125_5 Rdx family K07401 - - 0.0000000000005062 70.0
PYH2_k127_5629441_0 ABC-type multidrug transport system ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002651 533.0
PYH2_k127_5634729_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 6.426e-320 989.0
PYH2_k127_5634729_1 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006128 504.0
PYH2_k127_5634729_2 Prolyl oligopeptidase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000000108 230.0
PYH2_k127_5634729_3 GAF domain K08968 - 1.8.4.14 0.000000000000000000000000000000000000000000000001506 181.0
PYH2_k127_5640537_0 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 520.0
PYH2_k127_5640537_1 PFAM ABC transporter related K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 310.0
PYH2_k127_5640537_2 Uncharacterized protein family (UPF0051) K09014 - - 0.00000000000000000000000000000000000000000000000005126 194.0
PYH2_k127_5640537_3 - - - - 0.00000000000000000000000000001075 123.0
PYH2_k127_5640537_4 Transcriptional regulator - - - 0.00000000000000000000000006149 115.0
PYH2_k127_5640537_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01908 - 6.2.1.1,6.2.1.17 0.000000000000000000007456 93.0
PYH2_k127_5640537_6 acyl carrier protein - - - 0.0000000005866 63.0
PYH2_k127_5640537_7 Outer membrane protein beta-barrel domain - - - 0.0001297 52.0
PYH2_k127_5652082_0 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005913 483.0
PYH2_k127_5652082_1 PFAM Rubrerythrin - - - 0.00000000000000000000000000000000000000000000003186 176.0
PYH2_k127_5658190_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.679e-264 827.0
PYH2_k127_5658190_1 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004427 290.0
PYH2_k127_5658190_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.00000000000000000000000000000000000000000000000000000000002576 218.0
PYH2_k127_5658190_3 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000022 94.0
PYH2_k127_5658190_4 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000007705 84.0
PYH2_k127_5658755_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01007,K08483 - 2.7.3.9,2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 440.0
PYH2_k127_5658755_1 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 356.0
PYH2_k127_5658755_10 regulation of translation K05808,K05809 GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006417,GO:0006446,GO:0006448,GO:0006950,GO:0008150,GO:0009266,GO:0009409,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0017148,GO:0019222,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0043021,GO:0043022,GO:0043024,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0045900,GO:0045947,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000001259 99.0
PYH2_k127_5658755_11 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000003878 88.0
PYH2_k127_5658755_12 chromosome partitioning K03496 - - 0.000000000003364 66.0
PYH2_k127_5658755_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 351.0
PYH2_k127_5658755_3 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 312.0
PYH2_k127_5658755_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001029 252.0
PYH2_k127_5658755_5 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000004421 217.0
PYH2_k127_5658755_6 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000001292 177.0
PYH2_k127_5658755_7 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000002562 121.0
PYH2_k127_5658755_8 Mannose-6-phosphate isomerase - - - 0.0000000000000000000000000004425 127.0
PYH2_k127_5658755_9 TIGRFAM Phosphotransferase System HPr (HPr) Family K11189 - - 0.000000000000000000000002389 105.0
PYH2_k127_5679312_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 4.82e-259 835.0
PYH2_k127_5679312_1 Amidohydrolase family - - - 0.000000000000000000000000005878 123.0
PYH2_k127_5679312_2 Outer membrane protein beta-barrel domain - - - 0.0009133 46.0
PYH2_k127_5679412_0 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 486.0
PYH2_k127_5679412_1 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 362.0
PYH2_k127_5679412_2 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000002632 90.0
PYH2_k127_5679412_3 cyclic nucleotide-binding K10914 - - 0.000000000689 72.0
PYH2_k127_5709693_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 364.0
PYH2_k127_5709693_1 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 321.0
PYH2_k127_5709693_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 298.0
PYH2_k127_5709693_3 Deoxynucleoside kinase K10353 - 2.7.1.76 0.00000000000000000000000000000000000000000000000000008172 192.0
PYH2_k127_5709693_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642,K03749 - - 0.000005315 56.0
PYH2_k127_5726469_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 390.0
PYH2_k127_5726469_1 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000002576 250.0
PYH2_k127_5726469_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000002249 159.0
PYH2_k127_5726469_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000008578 154.0
PYH2_k127_5726469_4 Iron--sulfur cluster insertion protein erpA K15724 - - 0.00000000000000000000000000000003229 132.0
PYH2_k127_5726469_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000141 110.0
PYH2_k127_5726469_6 PDZ domain - - - 0.0000000000000000004056 99.0
PYH2_k127_5729215_0 PFAM ABC transporter related K09691 - - 0.0000000000000000000008258 103.0
PYH2_k127_5729215_1 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000005796 86.0
PYH2_k127_5729215_2 Bacterial membrane protein, YfhO - - - 0.00000000000000003456 96.0
PYH2_k127_5729215_3 Type II secretion system (T2SS), protein G K02456 - - 0.000002113 57.0
PYH2_k127_5732842_0 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 430.0
PYH2_k127_5732842_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 370.0
PYH2_k127_5732842_2 oxidoreductase gamma subunit K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000000000006773 200.0
PYH2_k127_5736637_0 CBS domain containing protein K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 489.0
PYH2_k127_5743115_0 Aldo/keto reductase family K05275 - 1.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 504.0
PYH2_k127_5743115_1 Cupin 2, conserved barrel domain protein - - - 0.00000005334 55.0
PYH2_k127_5754214_0 B12 binding domain - - - 1.474e-195 620.0
PYH2_k127_5754214_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 437.0
PYH2_k127_5754214_2 periplasmic ligand-binding sensor domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001717 336.0
PYH2_k127_5754214_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 310.0
PYH2_k127_5754214_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000003557 237.0
PYH2_k127_5754214_5 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000000002467 97.0
PYH2_k127_5776532_0 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 562.0
PYH2_k127_5786674_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 297.0
PYH2_k127_5786674_1 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000000000000000000000000000000000000007708 227.0
PYH2_k127_5807843_0 geranylgeranyl reductase activity K14257 - 1.14.19.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 298.0
PYH2_k127_5807843_1 Mycolic acid cyclopropane synthetase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003485 273.0
PYH2_k127_5811376_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000001535 233.0
PYH2_k127_5811376_1 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog - - - 0.000000000000000000000000000000000000000000000001663 180.0
PYH2_k127_5817809_0 translation release factor activity - - - 0.00000000000000000000000000000000000000000000002983 184.0
PYH2_k127_5817809_1 rRNA methyltransferase 1 K15507 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 - 0.000003497 51.0
PYH2_k127_5818773_0 5' nucleotidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 601.0
PYH2_k127_5818773_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 526.0
PYH2_k127_5818773_2 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 309.0
PYH2_k127_5818773_3 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 299.0
PYH2_k127_5818773_4 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 311.0
PYH2_k127_5831139_0 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 547.0
PYH2_k127_5831139_1 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000006604 200.0
PYH2_k127_5831139_2 DNA binding - - - 0.0000000000000000000000000000000000001212 147.0
PYH2_k127_5838857_0 lysine biosynthetic process via aminoadipic acid - - - 2.723e-216 691.0
PYH2_k127_5838857_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 340.0
PYH2_k127_5838857_2 homocysteine S-methyltransferase K00547 - 2.1.1.10 0.00000002863 58.0
PYH2_k127_5842456_0 tRNA processing K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002523 267.0
PYH2_k127_5842456_1 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000002919 241.0
PYH2_k127_5842456_2 Mechanosensitive ion channel - - - 0.00000000000001477 81.0
PYH2_k127_5842865_0 Orn/Lys/Arg decarboxylase, N-terminal domain K01581 - 4.1.1.17 0.0 1137.0
PYH2_k127_5842865_1 PFAM Orn Lys Arg decarboxylase major region K01582,K01584 - 4.1.1.18,4.1.1.19 0.0 1040.0
PYH2_k127_5842865_2 Amino acid permease K03756,K03759 - - 6.723e-230 717.0
PYH2_k127_5842865_3 Zn_pept - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003914 432.0
PYH2_k127_5842865_4 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004735 277.0
PYH2_k127_5842865_5 Amino acid permease K03294,K03759 - - 0.0000000000000000000000000000000000000000000000000000000000001042 218.0
PYH2_k127_5842865_6 Alginate export - - - 0.000000000000000000000000000000000000000000000000000000002393 219.0
PYH2_k127_5842865_7 Esterase-like activity of phytase K01126 - 3.1.4.46 0.000000000000000000000000002006 117.0
PYH2_k127_5842865_8 - - - - 0.000000000000001732 83.0
PYH2_k127_5855738_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K00207,K00219,K00317,K02293,K10797,K12527,K17723 - 1.3.1.1,1.3.1.2,1.3.1.31,1.3.1.34,1.3.5.5,1.5.8.1,1.5.8.2,1.97.1.9 5.01e-264 841.0
PYH2_k127_5855738_1 Pyridoxal-phosphate dependent enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 517.0
PYH2_k127_5855738_2 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 421.0
PYH2_k127_5890672_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 371.0
PYH2_k127_5890672_1 - K15977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003509 342.0
PYH2_k127_5901614_0 Sugar phosphate permease K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 480.0
PYH2_k127_5901614_1 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856,K10710,K22026 - 2.7.1.15,2.7.1.20,2.7.1.213,2.7.1.218,2.7.1.73 0.0000000000000000000000000000000000000001486 161.0
PYH2_k127_5925198_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 574.0
PYH2_k127_5925198_1 Belongs to the MurCDEF family K01924 GO:0000166,GO:0000270,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008763,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034645,GO:0035639,GO:0036094,GO:0042546,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0046872,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006972 471.0
PYH2_k127_5925198_2 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 353.0
PYH2_k127_5925198_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004003 340.0
PYH2_k127_5925198_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 GO:0000166,GO:0003674,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0030554,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000003899 211.0
PYH2_k127_5925198_5 Glycosyltransferase family 28 N-terminal domain K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000004393 168.0
PYH2_k127_5925198_6 PFAM thioesterase superfamily - - - 0.000000000000008361 74.0
PYH2_k127_5925198_7 - - - - 0.00000002956 61.0
PYH2_k127_5925198_8 Cell division protein FtsQ K03589 - - 0.00004357 54.0
PYH2_k127_5935752_0 Glycosyl transferase 4-like K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 391.0
PYH2_k127_5935752_1 PFAM LmbE family protein K01463 - - 0.000000000000000000000004822 108.0
PYH2_k127_5938950_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006143 319.0
PYH2_k127_5938950_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.000000000000008823 74.0
PYH2_k127_5941948_0 Aconitase C-terminal domain K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 503.0
PYH2_k127_5941948_1 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000003964 265.0
PYH2_k127_5941948_2 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000001033 251.0
PYH2_k127_5941948_3 Elongation factor P, C-terminal K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000002161 196.0
PYH2_k127_5941948_4 Flavin reductase like domain - - - 0.000000000000000000000000002088 117.0
PYH2_k127_5941948_5 SNARE associated Golgi protein - - - 0.00000001832 56.0
PYH2_k127_5956507_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005825 519.0
PYH2_k127_5956507_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 303.0
PYH2_k127_5956507_2 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000002759 221.0
PYH2_k127_5956507_3 Cell wall formation K00075 GO:0000270,GO:0003674,GO:0003824,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008762,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0030203,GO:0034645,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0055114,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 1.3.1.98 0.00000000000000000000000000000000000000000002438 168.0
PYH2_k127_5956507_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000000000003399 119.0
PYH2_k127_5956507_5 Formiminotransferase domain, N-terminal subdomain K13990 GO:0000139,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005789,GO:0005790,GO:0005793,GO:0005794,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006547,GO:0006548,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0006996,GO:0007010,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009987,GO:0012505,GO:0015631,GO:0016020,GO:0016043,GO:0016054,GO:0016740,GO:0016741,GO:0016742,GO:0016829,GO:0016840,GO:0016841,GO:0019215,GO:0019439,GO:0019752,GO:0030407,GO:0030409,GO:0030412,GO:0030868,GO:0031090,GO:0031984,GO:0034641,GO:0042175,GO:0042558,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046395,GO:0046483,GO:0046700,GO:0051186,GO:0052803,GO:0052805,GO:0071704,GO:0071840,GO:0071944,GO:0097425,GO:0098588,GO:0098791,GO:0098827,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.5,4.3.1.4 0.00000000000009228 78.0
PYH2_k127_5975351_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 385.0
PYH2_k127_5975351_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 310.0
PYH2_k127_5975351_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000001924 204.0
PYH2_k127_5975351_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000001763 159.0
PYH2_k127_5978171_0 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000001635 228.0
PYH2_k127_5978171_1 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000001187 192.0
PYH2_k127_5978171_2 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000006196 180.0
PYH2_k127_5978171_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000003899 169.0
PYH2_k127_5978171_4 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000003332 138.0
PYH2_k127_5985040_0 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 7.741e-197 627.0
PYH2_k127_5985040_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 369.0
PYH2_k127_5985040_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. Glycine N-methyltransferase family K18896 GO:0001505,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006544,GO:0006575,GO:0006577,GO:0006578,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008757,GO:0009058,GO:0009069,GO:0009987,GO:0016740,GO:0016741,GO:0017144,GO:0017174,GO:0019286,GO:0019752,GO:0031455,GO:0031456,GO:0032259,GO:0034641,GO:0042133,GO:0042398,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0052730,GO:0065007,GO:0065008,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.1.1.156 0.0002301 52.0
PYH2_k127_5985040_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 337.0
PYH2_k127_5985040_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 327.0
PYH2_k127_5985040_4 Cytochrome c554 and c-prime K03620 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 331.0
PYH2_k127_5985040_5 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 300.0
PYH2_k127_5985040_6 Belongs to the citrate synthase family K01647,K15234 - 2.3.3.1,4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000002817 248.0
PYH2_k127_5985040_7 PFAM Amidohydrolase 2 K01686 - 4.2.1.8 0.00000000000000000000000000000003232 142.0
PYH2_k127_5985040_9 Cytochrome b/b6/petB K00412 - - 0.000001032 53.0
PYH2_k127_5999927_0 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 331.0
PYH2_k127_5999927_1 transport, permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 318.0
PYH2_k127_5999927_2 ABC-2 family transporter protein K01992 - - 0.00000000000006282 75.0
PYH2_k127_6051086_0 PFAM Cytochrome c oxidase, subunit I K04561 - 1.7.2.5 1.273e-221 694.0
PYH2_k127_6051086_1 cytochrome c K02305 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 337.0
PYH2_k127_6051086_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000003144 226.0
PYH2_k127_6051086_3 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000005562 176.0
PYH2_k127_6051086_4 Peptidyl-prolyl cis-trans K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000008425 165.0
PYH2_k127_6064629_0 dipeptide transport K02035 - - 0.000000000000000000000000000000000001978 152.0
PYH2_k127_6064629_1 Domains HisKA, HATPase_c - - - 0.00000000000000000000000000000000004371 150.0
PYH2_k127_6086846_1 transporter, DctM subunit K11690 - - 0.00000000000000000000000000000001848 127.0
PYH2_k127_6086846_2 oligosaccharyl transferase activity - - - 0.0000000000000000000004909 112.0
PYH2_k127_610314_0 Domain of unknown function (DUF1956) - - - 0.0000000000000000000000000001659 123.0
PYH2_k127_610314_1 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) - - - 0.00000000000008907 82.0
PYH2_k127_6155473_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000000000000000000000000000006468 210.0
PYH2_k127_6155473_1 Linear amide C-N hydrolases, choloylglycine hydrolase family K01442 - 3.5.1.24 0.000000000000000000000000000000000000001256 162.0
PYH2_k127_6157008_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 9.117e-231 739.0
PYH2_k127_6157008_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 440.0
PYH2_k127_6168510_0 Phospholipase B - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 556.0
PYH2_k127_6168510_1 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000001001 164.0
PYH2_k127_6202433_0 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 349.0
PYH2_k127_6202433_1 Chromosome Partitioning - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000271 264.0
PYH2_k127_6202433_2 Domain of unknown function (DUF4010) - - - 0.00000000000000000000000000000000000000000003231 165.0
PYH2_k127_6202433_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000006281 142.0
PYH2_k127_6202433_4 pfam chad - - - 0.000000000000000000000005419 107.0
PYH2_k127_6229672_0 PFAM ATP-binding region, ATPase domain protein K07636 - 2.7.13.3 0.00000000000000000000000000000000000000003363 160.0
PYH2_k127_6229672_1 metal-dependent phosphohydrolase HD sub K00970 - 2.7.7.19 0.00000000000000000000001022 112.0
PYH2_k127_6455997_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 479.0
PYH2_k127_6455997_1 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004835 299.0
PYH2_k127_6539515_0 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000005272 178.0
PYH2_k127_6539515_1 Mechanosensitive ion channel - - - 0.00000000000000007707 91.0
PYH2_k127_6539515_2 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000008052 64.0
PYH2_k127_6549984_0 PFAM HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003137 370.0
PYH2_k127_6549984_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 360.0
PYH2_k127_6549984_2 PFAM peptidase S1 and S6, chymotrypsin Hap K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 351.0
PYH2_k127_6549984_3 serine-type peptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002949 317.0
PYH2_k127_6549984_4 Organic solvent tolerance protein K04744 - - 0.00000000000000000000000000000000000000000000000000002527 214.0
PYH2_k127_6549984_5 GAF domain - - - 0.00000000000000000000000000000000000000000000000000006964 201.0
PYH2_k127_6549984_6 protein kinase activity - - - 0.00000000000000000000000000000000000000000004015 182.0
PYH2_k127_6549984_7 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000002871 88.0
PYH2_k127_6549984_8 Oxygen tolerance - - - 0.000000002351 70.0
PYH2_k127_6562872_0 Asparagine synthase K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 316.0
PYH2_k127_6562872_1 COG0644 Dehydrogenases (flavoproteins) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008705 269.0
PYH2_k127_6562872_2 Aminotransferase, class V - - - 0.000000000000000000000000000000000000000000000000000000000000000002435 244.0
PYH2_k127_6562872_3 ABC transporter transmembrane K18890 - - 0.0000000000000000000008752 105.0
PYH2_k127_6574123_0 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 424.0
PYH2_k127_6574123_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K12450 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46,4.2.1.76 0.0000000000000000000000000000000000000000000000000000000000000000001013 235.0
PYH2_k127_6574123_2 GTP cyclohydrolase 1 K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000001985 188.0
PYH2_k127_6574123_3 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000001975 72.0
PYH2_k127_6576985_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 411.0
PYH2_k127_6576985_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000003367 129.0
PYH2_k127_6576985_2 Glucose inhibited division protein A K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000005084 85.0
PYH2_k127_6578592_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 365.0
PYH2_k127_6578592_1 Amino acid kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003203 346.0
PYH2_k127_6578592_2 Adenylosuccinate lyase C-terminus K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006082,GO:0006106,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.00000000000000007288 91.0
PYH2_k127_6584536_1 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 423.0
PYH2_k127_6584536_2 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000001174 177.0
PYH2_k127_6584536_3 - - - - 0.00000000000000000000002112 108.0
PYH2_k127_6584536_4 Aldehyde dehydrogenase family - - - 0.00000000000000001697 82.0
PYH2_k127_6593702_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 407.0
PYH2_k127_6593702_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000008201 183.0
PYH2_k127_6593702_2 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000004035 133.0
PYH2_k127_6593702_3 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000406 99.0
PYH2_k127_6593702_4 Yip1 domain - - - 0.00000000000000000002818 100.0
PYH2_k127_6593702_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000007577 87.0
PYH2_k127_6609555_0 Seven times multi-haem cytochrome CxxCH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 536.0
PYH2_k127_6609555_1 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000008486 166.0
PYH2_k127_6617435_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 321.0
PYH2_k127_6617435_1 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009373 275.0
PYH2_k127_6617435_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000001396 182.0
PYH2_k127_6617435_3 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000844 76.0
PYH2_k127_6634657_0 TonB dependent receptor K02014 - - 3.319e-227 730.0
PYH2_k127_6634657_1 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 568.0
PYH2_k127_6634657_2 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004248 347.0
PYH2_k127_6634657_3 Domain of unknown function (DUF4143) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 316.0
PYH2_k127_6634657_4 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000007084 258.0
PYH2_k127_6634657_5 Protein of unknown function (DUF559) - - - 0.000000000000000000000000000000006647 131.0
PYH2_k127_6663992_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 336.0
PYH2_k127_6663992_1 Beta-eliminating lyase K01667 - 4.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009578 283.0
PYH2_k127_6663992_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000002252 176.0
PYH2_k127_6663992_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.0000000000000002184 83.0
PYH2_k127_6665714_0 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000006078 196.0
PYH2_k127_6665714_1 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000001408 146.0
PYH2_k127_6665714_2 peptidyl-tyrosine sulfation - - - 0.0009605 51.0
PYH2_k127_6676068_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.000000000000000000000000000000000000000106 175.0
PYH2_k127_6679819_0 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000003381 228.0
PYH2_k127_6679819_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000003314 181.0
PYH2_k127_6679819_2 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000001307 109.0
PYH2_k127_6705839_0 D-aminopeptidase K16203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006713 270.0
PYH2_k127_6705839_1 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003861 239.0
PYH2_k127_6705839_2 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.00000003677 55.0
PYH2_k127_6712908_0 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007411 271.0
PYH2_k127_6712908_1 Type II/IV secretion system protein K02669 - - 0.00000000000000001483 88.0
PYH2_k127_6729522_0 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000008109 261.0
PYH2_k127_6729522_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000000000000000000000000000876 147.0
PYH2_k127_6729522_2 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000000000000000004453 137.0
PYH2_k127_6747988_0 Oligopeptidase F K08602 - - 2.498e-204 664.0
PYH2_k127_6747988_1 COG0616 Periplasmic serine proteases (ClpP class) K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 371.0
PYH2_k127_6747988_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000002663 226.0
PYH2_k127_6747988_3 - - - - 0.000000000000000000000000000000000000000003053 160.0
PYH2_k127_6747988_4 NmrA-like family - - - 0.0001335 49.0
PYH2_k127_6776357_0 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000909 336.0
PYH2_k127_6776357_1 OsmC-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002879 239.0
PYH2_k127_6776357_2 SnoaL-like domain - - - 0.000000000002877 68.0
PYH2_k127_6776725_0 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000001021 177.0
PYH2_k127_6776725_1 SnoaL-like polyketide cyclase - - - 0.000000000000000000000004834 109.0
PYH2_k127_6776725_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000002919 60.0
PYH2_k127_6779721_0 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 567.0
PYH2_k127_6779721_1 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 509.0
PYH2_k127_6779721_10 Tetratricopeptide repeat - - - 0.00000000000002433 87.0
PYH2_k127_6779721_11 Domain of unknown function (DUF4388) - - - 0.000000001509 68.0
PYH2_k127_6779721_12 Putative zinc-finger - - - 0.00001205 55.0
PYH2_k127_6779721_13 - - - - 0.00006935 45.0
PYH2_k127_6779721_2 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 449.0
PYH2_k127_6779721_3 Two component, sigma54 specific, transcriptional regulator, Fis family K07713,K07714,K19641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 413.0
PYH2_k127_6779721_4 Utp--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 316.0
PYH2_k127_6779721_5 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000006438 241.0
PYH2_k127_6779721_6 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000401 121.0
PYH2_k127_6779721_7 Sigma-70 region 2 K03088 - - 0.0000000000000000000000003578 113.0
PYH2_k127_6779721_8 PFAM Type II secretion system F domain K02653 - - 0.000000000000000000003342 104.0
PYH2_k127_6779721_9 Regulatory protein, FmdB - - - 0.000000000000000003556 88.0
PYH2_k127_6798938_0 Elongator protein 3, MiaB family, Radical SAM K22318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 322.0
PYH2_k127_6798938_1 PFAM DGPFAETKE family protein - - - 0.000000000000000000000000000000000000000000000000000000000000001769 228.0
PYH2_k127_6798938_2 radical SAM domain protein K22318 - - 0.00000000000004363 77.0
PYH2_k127_6818080_0 COG1668 ABC-type Na efflux pump, permease component K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000002236 237.0
PYH2_k127_6818080_1 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000001644 126.0
PYH2_k127_6818080_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001892 51.0
PYH2_k127_6819687_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 557.0
PYH2_k127_6819687_1 Aldo/keto reductase family K19265 - - 0.00000000000000000000000000000000000000000000000000000000000007273 214.0
PYH2_k127_6819687_2 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000303 189.0
PYH2_k127_6819687_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.0000000000001949 75.0
PYH2_k127_6828837_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 5.728e-236 739.0
PYH2_k127_6828837_1 Biotin carboxylase C-terminal domain K11263 - 6.3.4.14,6.4.1.2,6.4.1.3 0.000000000000000000000000000000000000000000001273 169.0
PYH2_k127_6831969_0 PFAM Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002858 523.0
PYH2_k127_6835479_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 432.0
PYH2_k127_6835479_1 Cysteine-rich domain K00113 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 432.0
PYH2_k127_6835479_10 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000003024 88.0
PYH2_k127_6835479_11 RESPONSE REGULATOR receiver - - - 0.0007338 47.0
PYH2_k127_6835479_2 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 432.0
PYH2_k127_6835479_3 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000159 278.0
PYH2_k127_6835479_4 COG4775 Outer membrane protein protective antigen OMA87 - - - 0.00000000000000000000000000000000000000000000000000000000003408 227.0
PYH2_k127_6835479_5 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000001602 203.0
PYH2_k127_6835479_6 DinB family - - - 0.00000000000000000000000000000000000000000001307 169.0
PYH2_k127_6835479_7 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000001564 145.0
PYH2_k127_6835479_8 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000003095 141.0
PYH2_k127_6835479_9 Binds the 23S rRNA K02909 - - 0.0000000000000000000000003048 106.0
PYH2_k127_6856160_0 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006437 392.0
PYH2_k127_6856160_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 375.0
PYH2_k127_6856160_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 356.0
PYH2_k127_6856160_3 Biotin-lipoyl like - - - 0.0001011 44.0
PYH2_k127_6876797_0 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000002069 145.0
PYH2_k127_6882939_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005093 454.0
PYH2_k127_6882939_1 AIPR protein - - - 0.00000001921 67.0
PYH2_k127_6882939_2 4 iron, 4 sulfur cluster binding - - - 0.0000001673 55.0
PYH2_k127_6882939_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000001619 61.0
PYH2_k127_6882939_4 Heat shock protein DnaJ domain protein - - - 0.00003267 55.0
PYH2_k127_6885114_0 Thioesterase superfamily K10806 - - 0.00000000000000000000000000000000001027 140.0
PYH2_k127_6885114_1 Maf-like protein K06287 - - 0.000000000000000000000000000000002124 136.0
PYH2_k127_6885114_2 PFAM AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000003213 132.0
PYH2_k127_6885114_3 SMART Tetratricopeptide - - - 0.00000000000000001224 91.0
PYH2_k127_6885114_4 Class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000008312 76.0
PYH2_k127_6926650_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 456.0
PYH2_k127_6936571_0 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000006636 233.0
PYH2_k127_6936571_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP - - - 0.00000000000000000000000000000000000000000000000006276 192.0
PYH2_k127_6951506_0 Sugar transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001837 295.0
PYH2_k127_6951506_1 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000001341 136.0
PYH2_k127_6975535_0 PFAM transposase, IS4 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 318.0
PYH2_k127_6975535_1 mRNA binding - - - 0.000000000000000000004698 97.0
PYH2_k127_6978447_0 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 421.0
PYH2_k127_6978447_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009802 388.0
PYH2_k127_6978447_2 Belongs to the glycosyl hydrolase 57 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009763 313.0
PYH2_k127_6978447_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042886,GO:0042887,GO:0043953,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000000000004259 116.0
PYH2_k127_6978447_4 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000008033 55.0
PYH2_k127_6982247_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003325 276.0
PYH2_k127_6982247_1 peptidase inhibitor activity - - - 0.00000000000000003621 93.0
PYH2_k127_7005749_0 UDP binding domain K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 564.0
PYH2_k127_7005749_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 395.0
PYH2_k127_7005749_2 radicals which are normally produced within the cells and which are toxic to biological systems K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001346 271.0
PYH2_k127_7005749_3 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000001094 177.0
PYH2_k127_7005749_4 LemA family K03744 - - 0.000000000000000007963 83.0
PYH2_k127_7014201_0 sulfatase K01130 - 3.1.6.1 9.49e-234 734.0
PYH2_k127_7014201_1 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 377.0
PYH2_k127_7014201_2 Catalyzes a two-step reaction, first charging a glutamine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA K01886 - 6.1.1.18 0.00000000000000000000000000006329 117.0
PYH2_k127_7014201_3 AraC-binding-like domain - - - 0.000000000000002613 85.0
PYH2_k127_7014201_4 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000003649 87.0
PYH2_k127_70185_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002761 233.0
PYH2_k127_70185_1 SMART Nucleotide binding protein, PINc K07175 - - 0.0000000000000000000000000000000000001413 159.0
PYH2_k127_7057564_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K20447 - 1.17.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 368.0
PYH2_k127_7057564_1 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.000004207 49.0
PYH2_k127_7059268_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 295.0
PYH2_k127_7059268_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000002716 240.0
PYH2_k127_7059268_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000031 247.0
PYH2_k127_7107604_0 oxidoreductase activity - - - 0.00000000000002756 85.0
PYH2_k127_7116073_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 367.0
PYH2_k127_7116073_1 Peptidase C26 K07010 - - 0.000000000000000004119 87.0
PYH2_k127_7149126_0 DEAD/H associated K03724 - - 7.796e-215 682.0
PYH2_k127_7149126_1 Cytochrome c554 and c-prime - - - 3.974e-210 668.0
PYH2_k127_7149126_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001317 349.0
PYH2_k127_7149126_3 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000002437 208.0
PYH2_k127_7200214_0 Beta-eliminating lyase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 402.0
PYH2_k127_7200214_1 Citrate lyase, alpha subunit (CitF) K01643 - 2.8.3.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 369.0
PYH2_k127_7200214_2 COG1519 3-deoxy-D-manno-octulosonic-acid transferase K02527 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016740,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 298.0
PYH2_k127_7200214_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000009977 222.0
PYH2_k127_7200214_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000008399 202.0
PYH2_k127_7215028_0 carboxypeptidase - - - 7.758e-206 672.0
PYH2_k127_7215028_1 PFAM Integral membrane protein TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 305.0
PYH2_k127_7215028_2 Fumarase C C-terminus K01744 - 4.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000004437 259.0
PYH2_k127_7215028_3 Domain of unknown function (DUF4412) - - - 0.000009006 55.0
PYH2_k127_7296041_0 TonB-dependent Receptor Plug Domain K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 621.0
PYH2_k127_7296041_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 594.0
PYH2_k127_7296041_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001913 262.0
PYH2_k127_7307957_0 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 410.0
PYH2_k127_7307957_1 aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000001211 205.0
PYH2_k127_7307957_2 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.000000000000000000000000000007618 122.0
PYH2_k127_737693_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005651 444.0
PYH2_k127_737693_1 - - - - 0.00000000000000000000000000000000000000000000000000001594 204.0
PYH2_k127_737693_2 PFAM Aminotransferase class I and II - - - 0.00000000000000000000001998 102.0
PYH2_k127_73931_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 470.0
PYH2_k127_73931_1 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 346.0
PYH2_k127_7475088_0 aldo keto reductase K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 414.0
PYH2_k127_7475088_1 proline dipeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 365.0
PYH2_k127_7475088_2 lysine biosynthetic process via aminoadipic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 346.0
PYH2_k127_7475088_3 WD-40 repeat - - - 0.00000000000000003682 86.0
PYH2_k127_7478237_0 Sodium:solute symporter family - - - 5.625e-198 634.0
PYH2_k127_7478237_1 PFAM GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000502 248.0
PYH2_k127_7480668_0 ferrous iron transmembrane transporter activity K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 614.0
PYH2_k127_7480668_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 456.0
PYH2_k127_7480668_2 Chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 291.0
PYH2_k127_7480668_3 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001205 265.0
PYH2_k127_7480668_4 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000001103 227.0
PYH2_k127_7480668_5 PFAM iron dependent repressor K03709 - - 0.0000000000000000000000000000000000000000000000000006372 195.0
PYH2_k127_7480668_6 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000000000003682 153.0
PYH2_k127_7480668_7 Helix-turn-helix diphteria tox regulatory element K03709 - - 0.0000000000000000002194 96.0
PYH2_k127_7480668_8 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000005831 91.0
PYH2_k127_7480668_9 Polymer-forming cytoskeletal - - - 0.000001725 60.0
PYH2_k127_7495248_0 Protein of unknown function (DUF1684) K09164 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 289.0
PYH2_k127_7495248_1 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.0000000000000000000000000000000000000000000000000000001995 204.0
PYH2_k127_7495248_2 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.000000000000000000000000000000000000000000000005173 183.0
PYH2_k127_7510739_0 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 490.0
PYH2_k127_7513722_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 359.0
PYH2_k127_7513722_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000001373 186.0
PYH2_k127_7513722_2 - - - - 0.00000000000006306 76.0
PYH2_k127_7513722_3 Putative regulatory protein - - - 0.0000001242 59.0
PYH2_k127_7520185_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 361.0
PYH2_k127_7520185_1 ABC transporter K01990 - - 0.000000002561 58.0
PYH2_k127_7522430_0 Prokaryotic cytochrome b561 - - - 0.0 1132.0
PYH2_k127_7522430_1 glutamine synthetase K01915 - 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 506.0
PYH2_k127_7522430_2 peptidase activity, acting on L-amino acid peptides - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 484.0
PYH2_k127_7522430_3 Protein of unknown function (DUF4019) - - - 0.0000000004352 61.0
PYH2_k127_7522430_4 PFAM SMP-30 Gluconolaconase - - - 0.0000289 57.0
PYH2_k127_7529346_0 Belongs to the aldehyde dehydrogenase family K00294 - 1.2.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 374.0
PYH2_k127_7529346_1 Glycosyltransferase like family 2 K07011,K13659 - 2.4.1.264 0.000000000000000000000000000000000000000000000000000000002185 225.0
PYH2_k127_7529346_2 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000006435 160.0
PYH2_k127_7532367_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 373.0
PYH2_k127_7532367_1 Heat shock 70 kDa protein K04043 - - 0.0000000000000000000000000000000000000000000000000000006841 198.0
PYH2_k127_7539629_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.9e-226 721.0
PYH2_k127_7539629_1 TIGRFAM phosphoribosylaminoimidazolecarboxamide formyltransferase IMP cyclohydrolase K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 489.0
PYH2_k127_7539629_10 transcriptional regulator - - - 0.000001881 57.0
PYH2_k127_7539629_11 Bacterial alpha-L-rhamnosidase 6 hairpin glycosidase domain - - - 0.00001091 57.0
PYH2_k127_7539629_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0001622 51.0
PYH2_k127_7539629_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007572 336.0
PYH2_k127_7539629_3 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 310.0
PYH2_k127_7539629_4 Belongs to the FPP GGPP synthase family K02523 GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009108,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0042180,GO:0042181,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000206 227.0
PYH2_k127_7539629_5 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000001231 218.0
PYH2_k127_7539629_6 Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000001947 184.0
PYH2_k127_7539629_7 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000231 136.0
PYH2_k127_7539629_8 Transport and Golgi organisation 2 - - - 0.000000000000000000000000001661 121.0
PYH2_k127_7539629_9 Spore Coat K01790 - 5.1.3.13 0.0000000000000000000009996 107.0
PYH2_k127_7550238_0 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 550.0
PYH2_k127_7550238_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007583 439.0
PYH2_k127_7550238_2 Fumarate hydratase (Fumerase) K01676,K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 314.0
PYH2_k127_7550238_3 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002765 316.0
PYH2_k127_7550238_4 Fumarase C-terminus K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000005404 245.0
PYH2_k127_7550238_5 Glycosyl Transferase Family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001286 239.0
PYH2_k127_7550238_6 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000004774 228.0
PYH2_k127_7550238_7 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000002843 143.0
PYH2_k127_7550238_8 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000007297 130.0
PYH2_k127_7550238_9 PFAM 4Fe-4S ferredoxin, iron-sulfur binding K00176 - 1.2.7.3 0.0000000000000000000000006131 107.0
PYH2_k127_7550782_0 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003537 261.0
PYH2_k127_7550782_1 Putative molybdenum carrier - - - 0.00000000000000000000000000000000000000000000000004759 182.0
PYH2_k127_7550782_2 Carbon dioxide concentrating mechanism carboxysome shell protein - - - 0.00000000000000000000000003261 117.0
PYH2_k127_7550782_3 Ethanolamine utilisation protein EutN/carboxysome - - - 0.0000000000000000002864 96.0
PYH2_k127_7550782_4 Dehydrogenase - - - 0.00000005794 53.0
PYH2_k127_7550782_5 Ethanolamine utilization protein EutN K04028 - - 0.0000002342 62.0
PYH2_k127_7566674_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000001142 216.0
PYH2_k127_7574387_0 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000005292 164.0
PYH2_k127_7574387_1 Glycosyl transferase family 2 K20444 - - 0.00000000000000000000004089 113.0
PYH2_k127_7574387_2 PFAM Glycosyl transferase, group 1 - - - 0.0001275 54.0
PYH2_k127_7575153_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 353.0
PYH2_k127_7575153_1 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000003182 124.0
PYH2_k127_7575153_2 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000001896 92.0
PYH2_k127_7575153_3 - - - - 0.000002121 58.0
PYH2_k127_7581247_0 Recombination factor protein RarA K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 384.0
PYH2_k127_7581247_1 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000001779 202.0
PYH2_k127_7581247_2 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000008497 177.0
PYH2_k127_7581959_0 Outer membrane protein beta-barrel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008613 537.0
PYH2_k127_7581959_1 transcriptional regulator - - - 0.000000000000000000000002616 105.0
PYH2_k127_7586331_0 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000000007725 235.0
PYH2_k127_7586331_1 PFAM Glycosyl transferase family 2 K20534 - - 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
PYH2_k127_7586331_2 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000003801 204.0
PYH2_k127_7586331_3 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000001633 189.0
PYH2_k127_7586331_4 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000000003794 65.0
PYH2_k127_7586331_5 Peptidase, M28 - - - 0.0001911 55.0
PYH2_k127_7588757_0 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007068 267.0
PYH2_k127_7588757_1 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000000000000000000000000000000007181 212.0
PYH2_k127_7588757_2 - - - - 0.000000002868 68.0
PYH2_k127_7596520_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006833 433.0
PYH2_k127_7596520_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 326.0
PYH2_k127_7596520_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006199 287.0
PYH2_k127_7596520_3 Anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000006133 241.0
PYH2_k127_7596520_4 This gene contains a nucleotide ambiguity which may be the result of a sequencing error K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.000003361 53.0
PYH2_k127_7605235_0 Belongs to the PdxS SNZ family K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000006062 203.0
PYH2_k127_7605235_1 helix_turn_helix gluconate operon transcriptional repressor - - - 0.00000000000000000000000000000000000000000000005416 184.0
PYH2_k127_7605235_2 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000008253 65.0
PYH2_k127_7612346_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 482.0
PYH2_k127_7624438_0 antibiotic biosynthetic process K01434 - 3.5.1.11 1.237e-238 764.0
PYH2_k127_7624438_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 417.0
PYH2_k127_7624438_2 DNA alkylation repair enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000001429 241.0
PYH2_k127_7624438_3 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000001392 206.0
PYH2_k127_7624696_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 324.0
PYH2_k127_7624696_2 lipoprotein localization to outer membrane K02004 - - 0.0000000000000000000000000000000005809 132.0
PYH2_k127_763210_0 SMART band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 358.0
PYH2_k127_763210_1 Belongs to the succinate malate CoA ligase beta subunit family K01903 - 6.2.1.5 0.0000000000000000000000000000000000000008649 158.0
PYH2_k127_763210_2 FMN binding - - - 0.000000000000000000000000000009809 130.0
PYH2_k127_7641866_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 383.0
PYH2_k127_7641866_1 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000002852 128.0
PYH2_k127_7647399_0 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000006388 254.0
PYH2_k127_7647399_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002939 253.0
PYH2_k127_7647399_2 CHASE3 domain - - - 0.0000000000000000000000000000006656 134.0
PYH2_k127_7647399_3 - - - - 0.000000000000009587 85.0
PYH2_k127_7647399_4 - - - - 0.0000000008536 63.0
PYH2_k127_7652251_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 9.191e-225 710.0
PYH2_k127_7652251_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 422.0
PYH2_k127_7652251_2 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000368 257.0
PYH2_k127_7652251_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000001718 210.0
PYH2_k127_7652251_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000001342 128.0
PYH2_k127_7652251_5 PFAM Transglutaminase-like - - - 0.000000002103 69.0
PYH2_k127_7654602_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 6.692e-214 675.0
PYH2_k127_7655695_0 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01485,K11991 - 3.5.4.1,3.5.4.33 0.0000000000000000000000000000000000000000000002976 172.0
PYH2_k127_7655695_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000004841 118.0
PYH2_k127_7655695_2 Recombinase zinc beta ribbon domain K06400 - - 0.00000002273 56.0
PYH2_k127_7660847_0 Dihydroxyacetone kinase family K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 370.0
PYH2_k127_7660847_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 376.0
PYH2_k127_7660847_2 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000002199 170.0
PYH2_k127_7660847_3 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000001065 127.0
PYH2_k127_7660847_4 Transmembrane exosortase (Exosortase_EpsH) - - - 0.000000000000000000000000001703 118.0
PYH2_k127_7662971_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 369.0
PYH2_k127_7662971_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000003096 228.0
PYH2_k127_7662971_10 Ribosomal prokaryotic L21 protein K02888 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000003568 70.0
PYH2_k127_7662971_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000006439 220.0
PYH2_k127_7662971_3 sigma-54 factor interaction domain-containing protein K07714 - - 0.000000000000000000000000000000000000000000000000000002845 204.0
PYH2_k127_7662971_4 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000757 168.0
PYH2_k127_7662971_5 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.0000000000000000000000000000000000000002408 158.0
PYH2_k127_7662971_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000002162 124.0
PYH2_k127_7662971_7 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000008685 106.0
PYH2_k127_7662971_8 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000000000005466 108.0
PYH2_k127_7662971_9 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000008224 93.0
PYH2_k127_7665311_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006317 278.0
PYH2_k127_7673302_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 5.082e-257 807.0
PYH2_k127_7673363_0 Putative molybdenum carrier - - - 0.0000000000000000000000000000000000000000000002175 179.0
PYH2_k127_7673363_1 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000006774 141.0
PYH2_k127_7673363_2 Tetratricopeptide repeat - - - 0.000000000000000000000593 107.0
PYH2_k127_7676486_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1786.0
PYH2_k127_7676486_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007277 428.0
PYH2_k127_7676486_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 302.0
PYH2_k127_7677069_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000001697 207.0
PYH2_k127_7677069_1 glycoprotease K14742 - - 0.000000000008559 74.0
PYH2_k127_7678569_0 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 481.0
PYH2_k127_7678569_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005368 304.0
PYH2_k127_7678569_2 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000001415 259.0
PYH2_k127_7678569_3 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000066 250.0
PYH2_k127_7678569_4 PFAM Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000000000000000000000002591 200.0
PYH2_k127_7678569_5 glyoxalase III activity - - - 0.0000000000000000000000000000000000000000003669 165.0
PYH2_k127_7678569_6 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.00000000000000000000000000000000000002356 152.0
PYH2_k127_7678569_7 Small Multidrug Resistance protein K11741 - - 0.0000000000000000000000000000000000004824 146.0
PYH2_k127_7678569_8 - - - - 0.0000000000000000000000001922 109.0
PYH2_k127_7678569_9 Domain of unknown function (DUF2088) - - - 0.000000001467 65.0
PYH2_k127_7681058_0 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 370.0
PYH2_k127_7681058_1 Thermolysin metallopeptidase, alpha-helical domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 347.0
PYH2_k127_7681058_2 - - - - 0.000000000000000171 82.0
PYH2_k127_7682559_0 COG0798 Arsenite efflux pump ACR3 and related K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 469.0
PYH2_k127_7682559_1 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 470.0
PYH2_k127_7682559_10 DNA-binding transcription factor activity K03892,K21903 - - 0.0000000000000000000001529 102.0
PYH2_k127_7682559_11 SCP-2 sterol transfer family - - - 0.0000000000000000008266 88.0
PYH2_k127_7682559_12 redox-active disulfide protein 2 - - - 0.00000000000000000214 87.0
PYH2_k127_7682559_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 411.0
PYH2_k127_7682559_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000009832 254.0
PYH2_k127_7682559_4 Cytochrome C biogenesis protein K06196 - - 0.0000000000000000000000000000000000000000000000000006114 196.0
PYH2_k127_7682559_5 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000003833 164.0
PYH2_k127_7682559_6 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000000000000000000001522 160.0
PYH2_k127_7682559_7 cell redox homeostasis - - - 0.0000000000000000000000000000001213 128.0
PYH2_k127_7682559_8 Winged helix DNA-binding domain - - - 0.00000000000000000000000002765 116.0
PYH2_k127_7682559_9 Thioredoxin domain - - - 0.00000000000000000000002182 102.0
PYH2_k127_7683328_0 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000533 327.0
PYH2_k127_7683328_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000002422 239.0
PYH2_k127_7683328_2 - - - - 0.000000000006809 69.0
PYH2_k127_7684981_0 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 346.0
PYH2_k127_7684981_1 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002501 281.0
PYH2_k127_7687510_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 432.0
PYH2_k127_7687510_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000001838 160.0
PYH2_k127_7692393_0 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 566.0
PYH2_k127_7692393_1 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 393.0
PYH2_k127_7692393_10 Stage II sporulation K07315 - 3.1.3.3 0.0000000000000000000000000000000000000006251 166.0
PYH2_k127_7692393_11 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000000000000000000000000000000006084 159.0
PYH2_k127_7692393_12 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000009942 136.0
PYH2_k127_7692393_13 oligopeptide transport K03305 - - 0.0000000000000000001333 93.0
PYH2_k127_7692393_14 sigma factor antagonist activity K04757 - 2.7.11.1 0.00000000000000008317 85.0
PYH2_k127_7692393_15 antisigma factor binding - - - 0.0000000000000001351 87.0
PYH2_k127_7692393_2 Cytochrome bd terminal oxidase subunit I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 356.0
PYH2_k127_7692393_3 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008835 354.0
PYH2_k127_7692393_4 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 336.0
PYH2_k127_7692393_5 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 311.0
PYH2_k127_7692393_6 long-chain fatty acid transporting porin activity K06076 - - 0.0000000000000000000000000000000000000000000000000000000001909 219.0
PYH2_k127_7692393_7 lipase activity K15349 - - 0.00000000000000000000000000000000000000000000000001456 197.0
PYH2_k127_7692393_8 COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily - - - 0.000000000000000000000000000000000000000000000002594 179.0
PYH2_k127_7692393_9 SMART protein phosphatase 2C domain protein - - - 0.000000000000000000000000000000000000000000000002667 183.0
PYH2_k127_7719373_0 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 579.0
PYH2_k127_7719373_1 peptidase S9 prolyl oligopeptidase active site - GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008239,GO:0009056,GO:0009987,GO:0016787,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0042597,GO:0042802,GO:0042803,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044464,GO:0046983,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004269 289.0
PYH2_k127_7724469_0 Sugar phosphate permease K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 591.0
PYH2_k127_7724469_1 Zinc-binding dehydrogenase K22231 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 569.0
PYH2_k127_7724469_2 Outer membrane protein beta-barrel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 512.0
PYH2_k127_7724469_3 Part of the ABC transporter complex RbsABC involved in ribose import. Responsible for energy coupling to the transport system K10441,K10545,K10548 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 491.0
PYH2_k127_7724469_4 Belongs to the binding-protein-dependent transport system permease family K10439,K10440 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008805 429.0
PYH2_k127_7724469_5 purine nucleotide biosynthetic process K02529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 340.0
PYH2_k127_7724469_6 Histidine phosphatase superfamily (branch 2) K01093 - 3.1.3.2,3.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 343.0
PYH2_k127_7724469_7 Oxidoreductase family, C-terminal alpha/beta domain K00010 - 1.1.1.18,1.1.1.369 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 329.0
PYH2_k127_7724469_8 PFAM oxidoreductase domain protein, Oxidoreductase domain-containing protein K00010 - 1.1.1.18,1.1.1.369 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009654 317.0
PYH2_k127_7724469_9 pfkB family carbohydrate kinase - - - 0.0000000002027 68.0
PYH2_k127_7729045_0 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 3.307e-207 651.0
PYH2_k127_7733890_0 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 452.0
PYH2_k127_7733890_1 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000001595 234.0
PYH2_k127_7752687_0 Saccharopine dehydrogenase C-terminal domain K00293 - 1.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 461.0
PYH2_k127_7752687_1 Alanine dehydrogenase/PNT, N-terminal domain K00290,K14157 - 1.5.1.7,1.5.1.8,1.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006929 358.0
PYH2_k127_7752687_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000001986 176.0
PYH2_k127_7771138_0 PFAM transposase IS116 IS110 IS902 family - - - 0.00000000000000000000000000000000000004007 159.0
PYH2_k127_7771143_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002835 621.0
PYH2_k127_7771143_1 Signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000002177 165.0
PYH2_k127_7787458_0 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 410.0
PYH2_k127_7787458_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000003499 177.0
PYH2_k127_7787458_2 helix_turn_helix, mercury resistance K13640 - - 0.00000000000000000000000000000239 125.0
PYH2_k127_7787458_3 Hsp20/alpha crystallin family K13993 - - 0.000000005486 64.0
PYH2_k127_7837416_0 cell shape determining protein MreB K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 495.0
PYH2_k127_7837416_1 TIGRFAM acetyl coenzyme A synthetase (ADP forming), alpha domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 462.0
PYH2_k127_7837416_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 429.0
PYH2_k127_7837416_3 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 419.0
PYH2_k127_7837416_4 SurA N-terminal domain K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000001639 257.0
PYH2_k127_7837416_5 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000002388 177.0
PYH2_k127_7837416_6 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000001254 160.0
PYH2_k127_7837416_7 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000000000000000000000000000000002687 147.0
PYH2_k127_7837416_8 FecR protein - - - 0.0000000000000000002053 102.0
PYH2_k127_7837416_9 Involved in formation and maintenance of cell shape K03570 - - 0.00000002097 66.0
PYH2_k127_7839745_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 462.0
PYH2_k127_7839745_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 405.0
PYH2_k127_7839745_2 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000001142 156.0
PYH2_k127_7839745_3 spore germination K03605 - - 0.00000000000009089 83.0
PYH2_k127_7848233_0 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 361.0
PYH2_k127_7848233_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.00000000000000000000002664 115.0
PYH2_k127_7848233_2 TonB-dependent receptor K02014 - - 0.00000006091 59.0
PYH2_k127_7860900_0 Phosphoribulokinase / Uridine kinase family K00855,K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.19,2.7.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000147 271.0
PYH2_k127_7860900_1 PFAM PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000001995 163.0
PYH2_k127_7860900_2 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000000000000000000000003887 146.0
PYH2_k127_7860900_3 Hfq protein - - - 0.0000000000000000000000000003962 117.0
PYH2_k127_7860900_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0001219 55.0
PYH2_k127_7861786_0 Protein of unknown function (DUF2911) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 422.0
PYH2_k127_7861786_1 hydrolase of the alpha beta superfamily K07017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003507 253.0
PYH2_k127_7861786_2 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000003847 151.0
PYH2_k127_7861786_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000005071 118.0
PYH2_k127_7861786_4 Putative phosphatase (DUF442) - - - 0.0000000000000003948 87.0
PYH2_k127_7877989_0 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005866 557.0
PYH2_k127_7923065_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006656 284.0
PYH2_k127_7923065_1 Histidine kinase - - - 0.0000000003083 68.0
PYH2_k127_7930504_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00322 - 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 413.0
PYH2_k127_7930504_1 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 339.0
PYH2_k127_7930504_2 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002081 282.0
PYH2_k127_7930504_3 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002159 246.0
PYH2_k127_8023757_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.053e-195 619.0
PYH2_k127_8023757_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 371.0
PYH2_k127_8023757_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000007335 157.0
PYH2_k127_8112918_0 Oligopeptide transporter OPT - - - 7.984e-250 790.0
PYH2_k127_8112918_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 413.0
PYH2_k127_8112918_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000007517 142.0
PYH2_k127_8173479_0 Aldehyde dehydrogenase family K00131 - 1.2.1.9 1.151e-238 748.0
PYH2_k127_8173479_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004387 525.0
PYH2_k127_8173479_2 4Fe-4S binding domain K08358 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 328.0
PYH2_k127_8173479_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003512 287.0
PYH2_k127_8173479_4 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006945 250.0
PYH2_k127_8173479_5 NapC/NirT cytochrome c family, N-terminal region - GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.00000000000000000000000000000000005529 141.0
PYH2_k127_8176172_0 MotA TolQ ExbB proton channel K03561,K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000002667 227.0
PYH2_k127_8176172_1 DNA photolyase activity - - - 0.000000000000000000000000000000000000000002057 160.0
PYH2_k127_8176172_2 Tetratricopeptide repeat - - - 0.00000000000000000000001429 115.0
PYH2_k127_8176172_3 PFAM Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.000000000000000000003097 100.0
PYH2_k127_8176172_4 Biopolymer transport protein K03559,K03560 - - 0.000000000000000000006961 97.0
PYH2_k127_8176172_5 TIGRFAM TonB K03832 - - 0.00000000000000002363 91.0
PYH2_k127_8176172_6 Bacterial membrane protein, YfhO - - - 0.0000000000000002525 88.0
PYH2_k127_8182616_0 uridine kinase K00876 - 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 553.0
PYH2_k127_8182616_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 505.0
PYH2_k127_8182616_2 Queuine tRNA-ribosyltransferase K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 391.0
PYH2_k127_8182616_3 serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 331.0
PYH2_k127_8182616_4 isochorismatase K08281 - 3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000002571 234.0
PYH2_k127_8182616_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000001147 242.0
PYH2_k127_8182616_6 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions - - - 0.00000000000000000002539 93.0
PYH2_k127_8182616_7 Preprotein translocase subunit K03210 - - 0.000000000000000002221 88.0
PYH2_k127_8182616_8 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000001225 65.0
PYH2_k127_8182616_9 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000324 57.0
PYH2_k127_8216528_0 Amino acid kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009657 421.0
PYH2_k127_8216528_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000002238 287.0
PYH2_k127_8216528_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K09065 - 2.1.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000003384 257.0
PYH2_k127_8216528_3 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001238 243.0
PYH2_k127_8413090_0 Belongs to the dicarboxylate amino acid cation symporter (DAACS) (TC 2.A.23) family K03309 - - 0.0000000000000000000000000000000000000000000000003818 186.0
PYH2_k127_8413090_1 BlaR1 peptidase M56 - - - 0.0000000000008411 79.0
PYH2_k127_8413238_0 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005973 409.0
PYH2_k127_8413238_1 PFAM Phosphate-starvation-inducible - - - 0.000000000000000000000000000000000000000000000000000000007657 201.0
PYH2_k127_8413238_2 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000005402 132.0
PYH2_k127_8413238_3 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.00000000000009066 75.0
PYH2_k127_8413924_0 NUBPL iron-transfer P-loop NTPase K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 313.0
PYH2_k127_8413924_1 Belongs to the thioredoxin family K00384,K03671 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.9 0.0000000000000000000000000000000000000000001389 162.0
PYH2_k127_8413924_2 Oligoendopeptidase f - - - 0.0000000000000000000000003685 106.0
PYH2_k127_8413924_3 Helix-turn-helix domain - - - 0.0000000000005085 81.0
PYH2_k127_8414549_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1612.0
PYH2_k127_8414549_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 5.976e-200 635.0
PYH2_k127_8414549_2 HlyD membrane-fusion protein of T1SS K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004314 461.0
PYH2_k127_8414549_3 Flavodoxin-like fold K00355 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005712 276.0
PYH2_k127_8414549_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000002198 55.0
PYH2_k127_8414549_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000002281 53.0
PYH2_k127_8418132_0 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 357.0
PYH2_k127_8418132_1 Peptidase family C25 - - - 0.00000000000000000000000000000000000000000000000000000000000000004189 247.0
PYH2_k127_8420592_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K11529,K15893 - 1.1.1.26,2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 291.0
PYH2_k127_8420592_1 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000001136 210.0
PYH2_k127_8420592_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K03768 - 5.2.1.8 0.0000000000000000000000000000000000000002643 168.0
PYH2_k127_8429012_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 5.609e-219 702.0
PYH2_k127_8429012_1 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000006769 237.0
PYH2_k127_8429012_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000005828 227.0
PYH2_k127_8429012_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000003075 128.0
PYH2_k127_8429012_4 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000005288 91.0
PYH2_k127_8429012_5 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 GO:0000702,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006979,GO:0008150,GO:0008152,GO:0008534,GO:0009987,GO:0016020,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034039,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363 3.2.2.23,4.2.99.18 0.00000000003473 63.0
PYH2_k127_8429012_6 protein conserved in bacteria K09764 - - 0.00009747 47.0
PYH2_k127_8438069_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 462.0
PYH2_k127_8438069_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003148 467.0
PYH2_k127_8438069_2 Domain of unknown function DUF87 K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000236 236.0
PYH2_k127_8438069_3 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000000000000000000000000000000001458 225.0
PYH2_k127_8438069_4 B12 binding domain K14084 - - 0.000000000000000000000000000000000000000000000000000000000276 211.0
PYH2_k127_8438069_5 vitamin B12 dependent methionine synthase, activation K00548 - 2.1.1.13 0.0000000000001257 83.0
PYH2_k127_8444300_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 365.0
PYH2_k127_8444300_1 Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) K05365 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 311.0
PYH2_k127_8444300_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000002178 147.0
PYH2_k127_8451408_0 DinB family - - - 0.000000000000000000000000000000000000000001312 162.0
PYH2_k127_8451408_1 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.000000000006163 71.0
PYH2_k127_8459954_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 563.0
PYH2_k127_8459954_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 365.0
PYH2_k127_8459954_2 gluconolactonase activity K01053 - 3.1.1.17 0.000000000000000000000000000000001698 130.0
PYH2_k127_8461873_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008614,GO:0008615,GO:0008654,GO:0008661,GO:0009058,GO:0009108,GO:0009110,GO:0009228,GO:0009240,GO:0009987,GO:0016740,GO:0016744,GO:0017144,GO:0018130,GO:0019288,GO:0019438,GO:0019637,GO:0019682,GO:0019752,GO:0019842,GO:0030145,GO:0030975,GO:0030976,GO:0032787,GO:0034641,GO:0036094,GO:0040007,GO:0042180,GO:0042181,GO:0042364,GO:0042723,GO:0042724,GO:0042816,GO:0042819,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1901661,GO:1901663,GO:1901681 2.2.1.7 5.696e-226 717.0
PYH2_k127_8461873_1 Thiolase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 370.0
PYH2_k127_8461873_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 321.0
PYH2_k127_8461873_3 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000007152 255.0
PYH2_k127_8461873_4 O-Antigen ligase K18814 - - 0.000000000000000000000000006123 119.0
PYH2_k127_8461873_5 Glycosyltransferase Family 4 - - - 0.0000000000000000002786 104.0
PYH2_k127_8461873_6 Belongs to the UPF0434 family K09791 - - 0.00000000005157 68.0
PYH2_k127_8461873_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000001037 59.0
PYH2_k127_8462990_0 Porin subfamily - - - 0.00000000000000000000000000000000000000000000115 184.0
PYH2_k127_8462990_1 NMT1-like family K07080 - - 0.00000000000000000000000004697 111.0
PYH2_k127_8468475_0 Acetyl-CoA hydrolase/transferase N-terminal domain K01067 - 3.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 522.0
PYH2_k127_8468475_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 309.0
PYH2_k127_8468475_2 O-methyltransferase, family 2 - - - 0.0000000000000000000000000000000000000000000008581 180.0
PYH2_k127_8478153_0 transporter, DctM subunit K11690 - - 2.276e-222 704.0
PYH2_k127_8478153_1 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 385.0
PYH2_k127_8478153_3 TRAP transporter T-component - - - 0.00000000000000001581 83.0
PYH2_k127_8482666_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000001051 148.0
PYH2_k127_8482666_1 transcription factor binding - - - 0.00000000000000000000000000003952 122.0
PYH2_k127_8482666_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000004049 83.0
PYH2_k127_8482666_3 Protein of unknown function (DUF2723) - - - 0.00000000000004056 87.0
PYH2_k127_8482666_4 General transcription factor 3C polypeptide K15201 - - 0.0002323 49.0
PYH2_k127_8482939_0 Cleaves the N-terminal amino acid of tripeptides K01270 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016805,GO:0019538,GO:0034641,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070011,GO:0070573,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007993 451.0
PYH2_k127_8482939_1 TIGRFAM fructose-1,6-bisphosphatase, class II K02446 - 3.1.3.11 0.0000000000000002914 80.0
PYH2_k127_8482939_2 protein kinase activity - - - 0.00000002806 58.0
PYH2_k127_8485350_0 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009984 322.0
PYH2_k127_8485350_1 Outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000003137 226.0
PYH2_k127_8485350_2 L-aspartate oxidase K00278 - 1.4.3.16 0.000000000000000000000002854 117.0
PYH2_k127_8496594_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 5.694e-194 615.0
PYH2_k127_8496594_1 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000003324 142.0
PYH2_k127_8503254_0 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 449.0
PYH2_k127_8503254_1 Protein of unknown function (DUF2723) - - - 0.000004882 55.0
PYH2_k127_8506127_0 Belongs to the GcvT family K06980 - - 0.00000000000000000000000117 117.0
PYH2_k127_8506127_1 COG2059 Chromate transport protein ChrA K07240 - - 0.0000000000000001412 84.0
PYH2_k127_8506127_2 endonuclease containing a URI domain K07461 - - 0.0000000000003433 69.0
PYH2_k127_8511255_0 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000001414 241.0
PYH2_k127_8513827_0 H( )-stimulated, divalent metal cation uptake system K03322 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 456.0
PYH2_k127_8513827_1 Uncharacterized protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007915 262.0
PYH2_k127_8513827_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000005297 237.0
PYH2_k127_8513827_3 TIGRFAM hemolysin TlyA family protein K06442 GO:0000154,GO:0001510,GO:0001897,GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019835,GO:0019836,GO:0022613,GO:0031167,GO:0031640,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0035821,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044003,GO:0044004,GO:0044085,GO:0044179,GO:0044237,GO:0044238,GO:0044260,GO:0044364,GO:0044403,GO:0044419,GO:0044764,GO:0046483,GO:0051701,GO:0051704,GO:0051715,GO:0051801,GO:0051817,GO:0051818,GO:0051883,GO:0052331,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000001073 178.0
PYH2_k127_8513827_4 Lrp/AsnC ligand binding domain - - - 0.00000000000000004017 85.0
PYH2_k127_8523997_0 Putative citrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 533.0
PYH2_k127_8523997_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000001098 210.0
PYH2_k127_8523997_2 protein homooligomerization - - - 0.000000134 60.0
PYH2_k127_8538780_0 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 502.0
PYH2_k127_8538780_1 Catalyzes the conversion of UDP-4-keto-arabinose (UDP- Ara4O) to UDP-4-amino-4-deoxy-L-arabinose (UDP-L-Ara4N). The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides K07806 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0008483,GO:0016740,GO:0016769,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:0099620,GO:1901363 2.6.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007324 420.0
PYH2_k127_8538780_2 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 368.0
PYH2_k127_8538780_3 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 296.0
PYH2_k127_8538780_4 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000002517 267.0
PYH2_k127_8538780_5 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000004741 230.0
PYH2_k127_8538780_6 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000002005 170.0
PYH2_k127_8538780_7 Calcineurin-like phosphoesterase K03269 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0019897,GO:0019898,GO:0030145,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.6.1.54 0.00000000000000000000000004112 118.0
PYH2_k127_8581926_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 313.0
PYH2_k127_8581926_1 deaminase K01493 - 3.5.4.12 0.0000000000000000000000000000000000000000000000000000000003297 212.0
PYH2_k127_8581926_2 Peptidase family M48 - - - 0.0000000000000000000000000000000000000171 155.0
PYH2_k127_8581926_3 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000001912 99.0
PYH2_k127_8581926_4 Transcriptional regulator, Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.00000000307 69.0
PYH2_k127_8585861_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 546.0
PYH2_k127_8585861_1 ADP-ribosylation factor family K06883 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 298.0
PYH2_k127_8585861_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000003444 265.0
PYH2_k127_8585861_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 GO:0000287,GO:0003674,GO:0003824,GO:0003977,GO:0005488,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0019134,GO:0022610,GO:0030260,GO:0035635,GO:0040007,GO:0043167,GO:0043169,GO:0044403,GO:0044406,GO:0044409,GO:0044419,GO:0044650,GO:0046872,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0070569 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000002077 264.0
PYH2_k127_8585861_4 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000005954 219.0
PYH2_k127_8585861_5 PFAM Roadblock LC7 family protein - - - 0.0000000000000000000000000000000000000000000000000000003365 206.0
PYH2_k127_8585861_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000003769 83.0
PYH2_k127_8585861_7 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000008161 60.0
PYH2_k127_8594141_0 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 556.0
PYH2_k127_8594141_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 416.0
PYH2_k127_8594141_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001874 254.0
PYH2_k127_8594302_0 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 473.0
PYH2_k127_8602618_0 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 326.0
PYH2_k127_8602618_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000001075 215.0
PYH2_k127_8623249_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 1.338e-267 841.0
PYH2_k127_8623249_1 synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000002295 162.0
PYH2_k127_8623249_2 Belongs to the universal stress protein A family - - - 0.00000000000000000003959 101.0
PYH2_k127_8623249_3 NmrA-like family - - - 0.000005238 51.0
PYH2_k127_8624818_0 AAA domain (Cdc48 subfamily) K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001778 285.0
PYH2_k127_8624818_1 DEAD DEAH box K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000001065 233.0
PYH2_k127_8624818_2 PFAM Ankyrin repeat K06867 - - 0.000000000000000000000007994 112.0
PYH2_k127_8624818_3 Carboxypeptidase regulatory-like domain - - - 0.0000000000000000000005702 99.0
PYH2_k127_8635730_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 379.0
PYH2_k127_8635730_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000007069 119.0
PYH2_k127_8644111_0 SPFH domain-Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008245 305.0
PYH2_k127_8644111_1 - - - - 0.000000000000002582 82.0
PYH2_k127_8644111_2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000006051 59.0
PYH2_k127_8647761_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1266.0
PYH2_k127_8650300_0 Major Facilitator Superfamily - - - 0.000000000003798 78.0
PYH2_k127_8650300_1 - - - - 0.000000000265 70.0
PYH2_k127_8650300_2 DNA-templated transcription, initiation K03088 - - 0.000000002142 59.0
PYH2_k127_8650300_3 Domain of unknown function (DUF4136) - - - 0.0000002084 61.0
PYH2_k127_8674238_0 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
PYH2_k127_8674238_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008427 279.0
PYH2_k127_8674238_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0001871,GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005623,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010467,GO:0019538,GO:0030246,GO:0030247,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:2001065 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002439 263.0
PYH2_k127_8674238_3 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000006407 212.0
PYH2_k127_8674238_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001863 196.0
PYH2_k127_8674238_5 Ribosomal protein S9/S16 K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000001041 171.0
PYH2_k127_8674238_6 cellulose binding - - - 0.00000000000000000000000000000000000000000002074 173.0
PYH2_k127_8674238_7 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.0000000000002863 79.0
PYH2_k127_8686172_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 346.0
PYH2_k127_8686172_1 malic enzyme K00027,K00029,K00625,K13788 GO:0003674,GO:0003824,GO:0004470,GO:0004473,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0030145,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0055114 1.1.1.38,1.1.1.40,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008398 286.0
PYH2_k127_8686172_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000007903 74.0
PYH2_k127_8687863_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 381.0
PYH2_k127_8687863_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000346 255.0
PYH2_k127_8687863_2 RDD family - - - 0.0000000569 65.0
PYH2_k127_8690775_0 metallocarboxypeptidase activity K14054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 421.0
PYH2_k127_8690775_1 phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007038 376.0
PYH2_k127_8690775_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.0000009366 51.0
PYH2_k127_8721570_0 Integrase core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000007389 248.0
PYH2_k127_8721570_1 - - - - 0.000004199 50.0
PYH2_k127_8738732_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000001552 209.0
PYH2_k127_8738732_1 Serine phosphatase RsbU regulator of sigma subunit K07315 - 3.1.3.3 0.000000000000000000000000007709 123.0
PYH2_k127_8738732_2 helix_turn_helix gluconate operon transcriptional repressor K07979 - - 0.00000000000000000007381 94.0
PYH2_k127_8738732_3 Transcriptional regulator K07979 - - 0.0002308 53.0
PYH2_k127_8745517_0 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000001531 200.0
PYH2_k127_8745517_1 - - - - 0.00000000000000004842 90.0
PYH2_k127_8745517_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000008783 79.0
PYH2_k127_8745517_3 SMART helix-turn-helix domain protein - - - 0.000000000001829 78.0
PYH2_k127_8745517_4 - - - - 0.0000000006978 70.0
PYH2_k127_8782028_0 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002817 254.0
PYH2_k127_8782028_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000001064 225.0
PYH2_k127_8782028_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001111 189.0
PYH2_k127_8782028_3 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.000000000000000000000000000000000002362 140.0
PYH2_k127_8816765_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002657 285.0
PYH2_k127_8816765_1 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000005445 249.0
PYH2_k127_8816765_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000001939 183.0
PYH2_k127_8833090_0 PFAM peptidase U34 dipeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 517.0
PYH2_k127_8833090_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008048 344.0
PYH2_k127_8833090_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000009699 255.0
PYH2_k127_8833742_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 494.0
PYH2_k127_8833742_1 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 358.0
PYH2_k127_8833742_2 PFAM peptidase M48 Ste24p - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002842 279.0
PYH2_k127_8833742_3 Tricorn protease PDZ domain K08676 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007338 270.0
PYH2_k127_8833742_4 PAP2 superfamily K19302 - 3.6.1.27 0.0004079 51.0
PYH2_k127_8833742_5 PFAM phosphoesterase, PA-phosphatase related K19302 - 3.6.1.27 0.0004452 51.0
PYH2_k127_8866481_0 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000004489 242.0
PYH2_k127_8866481_1 DNA polymerase III, chi subunit K02339 - 2.7.7.7 0.00000009377 59.0
PYH2_k127_8866481_2 PFAM Peptidase M16 inactive domain K07263 - - 0.0008316 44.0
PYH2_k127_8898049_0 COG4584 Transposase and inactivated derivatives - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 426.0
PYH2_k127_8898049_1 - - - - 0.0000000000008329 75.0
PYH2_k127_8935343_0 diguanylate cyclase - - - 0.00000000000000000000003172 112.0
PYH2_k127_8953831_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 420.0
PYH2_k127_8953831_1 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000001016 168.0
PYH2_k127_8976448_0 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002035 312.0
PYH2_k127_8976448_1 alpha beta - - - 0.0000000000000000000000000000000000000002803 164.0
PYH2_k127_8976448_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000004331 154.0
PYH2_k127_8976448_3 GTP binding K06942 GO:0003674,GO:0003824,GO:0004857,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030234,GO:0043021,GO:0043022,GO:0043023,GO:0043086,GO:0044092,GO:0044424,GO:0044464,GO:0044877,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000669 133.0
PYH2_k127_8976448_4 - - - - 0.0000000000000000000000000000001156 134.0
PYH2_k127_8976448_5 - - - - 0.00000000000000000000000004596 124.0
PYH2_k127_8986902_0 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002393 284.0
PYH2_k127_8986902_1 Oxidoreductase activity. It is involved in the biological process described with metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000004122 216.0
PYH2_k127_8986902_2 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000103 151.0
PYH2_k127_8986902_3 Methyltransferase domain - - - 0.000000000000000000000000000000004132 136.0
PYH2_k127_8986902_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000003174 72.0
PYH2_k127_8993238_0 lactate metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 469.0
PYH2_k127_8993238_1 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000001237 130.0
PYH2_k127_8993238_2 nitrate reductase activity - - - 0.0000000000000000116 92.0
PYH2_k127_9001169_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 1.242e-287 897.0
PYH2_k127_9001169_1 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 1.183e-210 669.0
PYH2_k127_9001169_10 Anti-sigma regulatory factor (Ser Thr protein kinase) - - - 0.000000000000000000000000000000000006402 142.0
PYH2_k127_9001169_11 DRTGG domain - - - 0.000000000000000000001333 99.0
PYH2_k127_9001169_12 3-phytase (Myo-inositol-hexaphosphate 3-phosphohydrolase) K01083 - 3.1.3.8 0.0000000001332 65.0
PYH2_k127_9001169_13 DRTGG domain - - - 0.000000000237 66.0
PYH2_k127_9001169_2 SMART alpha amylase catalytic sub domain K01208 - 3.2.1.133,3.2.1.135,3.2.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 543.0
PYH2_k127_9001169_3 Molybdopterin oxidoreductase, Fe4S4 K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 521.0
PYH2_k127_9001169_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 504.0
PYH2_k127_9001169_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 358.0
PYH2_k127_9001169_6 Fe-S cluster domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 303.0
PYH2_k127_9001169_7 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009162 293.0
PYH2_k127_9001169_8 PFAM Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000005131 244.0
PYH2_k127_9001169_9 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003174 171.0
PYH2_k127_9051161_0 proteolysis - - - 0.00000000000000000000000000000000000000000000000000000000000001961 231.0
PYH2_k127_9051161_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000311 168.0
PYH2_k127_9070075_0 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 416.0
PYH2_k127_9070075_1 Cytochrome c554 and c-prime K03620 - - 0.000000000000000000000000000000000000008275 164.0
PYH2_k127_9070075_2 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.00001017 47.0
PYH2_k127_9078497_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000002485 167.0
PYH2_k127_9078497_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000005725 105.0
PYH2_k127_9078497_2 Peptidase family M23 K21471 - - 0.00000000000000000003678 105.0
PYH2_k127_9078497_3 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000006492 77.0
PYH2_k127_9130659_0 Mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000001205 186.0
PYH2_k127_9130659_1 phosphatase activity K07025 - - 0.00000000000000000000000000000000000000004507 160.0
PYH2_k127_9130659_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0033554,GO:0034599,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887 - 0.0000000000000003919 87.0
PYH2_k127_9130659_3 MOFRL family K11529 - 2.7.1.165 0.0000004031 58.0
PYH2_k127_934693_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 428.0
PYH2_k127_935345_0 Cleaves the N-terminal amino acid of tripeptides K01258 - 3.4.11.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 428.0
PYH2_k127_935345_1 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.00000000000000000000000000000000000002546 149.0
PYH2_k127_935345_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000002997 101.0
PYH2_k127_945713_0 formate dehydrogenase (NAD+) activity K00336,K18006 - 1.12.1.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 327.0
PYH2_k127_94720_0 Phosphoglucose isomerase K01810 - 5.3.1.9 2.938e-294 911.0
PYH2_k127_94720_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004215 403.0
PYH2_k127_94720_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 355.0
PYH2_k127_94720_3 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K03796 - - 0.00000000000000000000000000000000000000000000000000002187 195.0
PYH2_k127_94720_4 - - - - 0.0000000000000000000000000007224 119.0
PYH2_k127_948004_0 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 347.0
PYH2_k127_948004_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001702 238.0
PYH2_k127_948004_2 - - - - 0.000000001545 65.0
PYH2_k127_957510_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007082 501.0
PYH2_k127_957510_1 soluble inorganic pyrophosphatase K01507 GO:0003674,GO:0003824,GO:0004427,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000007458 210.0
PYH2_k127_957510_2 phosphonopyruvate decarboxylase K09459 - 4.1.1.82 0.00000000000000000000000000000000001229 143.0
PYH2_k127_957510_3 sequence-specific DNA binding - - - 0.000000000000000000000000006335 117.0
PYH2_k127_957510_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.000000000000000000000008376 110.0
PYH2_k127_957510_5 RES - - - 0.0000000000000000000001982 105.0
PYH2_k127_969094_0 proline dipeptidase activity K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006487 417.0
PYH2_k127_969094_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001465 261.0
PYH2_k127_969094_2 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000001022 252.0
PYH2_k127_969094_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000001705 184.0
PYH2_k127_969094_4 cell redox homeostasis K02199,K03671 - - 0.0000000000000000000000000000005531 130.0
PYH2_k127_969094_5 symporter activity K03307,K11928 - - 0.0000000000000000001167 90.0
PYH2_k127_973640_0 synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004842 271.0
PYH2_k127_973640_1 response regulator - - - 0.0000001794 61.0
PYH2_k127_973704_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 392.0
PYH2_k127_973704_1 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000001205 183.0
PYH2_k127_973704_2 protein-disulfide reductase activity - - - 0.0000000000000000000000008694 110.0
PYH2_k127_977066_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000043 367.0