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Overview

ID MAG03203
Name PYH2_bin.62
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum BMS3Abin14
Class BMS3Abin14
Order BMS3Abin14
Family
Genus
Species
Assembly information
Completeness (%) 96.19
Contamination (%) 1.28
GC content (%) 66.0
N50 (bp) 15,295
Genome size (bp) 2,097,789

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1903

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1038433_0 Belongs to the glutamate synthase family - - - 1.164e-245 766.0
PYH2_k127_1038433_1 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 1.366e-239 768.0
PYH2_k127_1038433_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 566.0
PYH2_k127_1038433_3 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 500.0
PYH2_k127_1038433_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 372.0
PYH2_k127_1038433_5 PFAM glutamate synthase alpha subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004233 276.0
PYH2_k127_1038433_6 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005224 197.0
PYH2_k127_1038433_7 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000000000000000000000000004257 174.0
PYH2_k127_1038433_8 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000215 124.0
PYH2_k127_1038433_9 - - - - 0.0002962 43.0
PYH2_k127_1059124_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 482.0
PYH2_k127_1059124_1 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 333.0
PYH2_k127_1059124_2 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004047 313.0
PYH2_k127_1059124_3 PFAM GGDEF domain containing protein, response regulator receiver - - - 0.00000000000000000000000000000000001934 147.0
PYH2_k127_1059124_4 THIoesterase K18700 - 3.1.2.29 0.00000000000000002753 89.0
PYH2_k127_1059124_5 long-chain fatty acid transporting porin activity - - - 0.0000000000000001571 92.0
PYH2_k127_1059124_6 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.0000000000001351 73.0
PYH2_k127_1059124_7 Glutaredoxin K03676 - - 0.000000002038 59.0
PYH2_k127_1064018_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 461.0
PYH2_k127_1064018_1 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 371.0
PYH2_k127_1064018_2 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000005562 226.0
PYH2_k127_1064018_3 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000001502 119.0
PYH2_k127_1103101_0 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 386.0
PYH2_k127_1103101_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001663 234.0
PYH2_k127_1103101_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000002166 220.0
PYH2_k127_1103101_3 - - - - 0.00000000000000000000006186 115.0
PYH2_k127_1103101_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000001815 70.0
PYH2_k127_1132820_0 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 7.048e-242 774.0
PYH2_k127_1132820_1 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 595.0
PYH2_k127_1132820_10 Domain of unknown function (DUF4912) K09942 - - 0.000000007189 66.0
PYH2_k127_1132820_2 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 550.0
PYH2_k127_1132820_3 Domain of unknown function (DUF1925) K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 516.0
PYH2_k127_1132820_4 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 488.0
PYH2_k127_1132820_5 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 411.0
PYH2_k127_1132820_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 390.0
PYH2_k127_1132820_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
PYH2_k127_1132820_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004902 285.0
PYH2_k127_1132820_9 response regulator - - - 0.000000000000000000000000000000501 127.0
PYH2_k127_1179330_0 Tetratricopeptide repeat - - - 0.0000000000000003345 88.0
PYH2_k127_1179330_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). - - - 0.000000001394 70.0
PYH2_k127_1179330_2 Peptidase family M28 - - - 0.0000001906 63.0
PYH2_k127_1179330_3 - - - - 0.0000007104 57.0
PYH2_k127_1179330_4 - - - - 0.000001615 60.0
PYH2_k127_119768_0 Heat shock 70 kDa protein K04043 - - 5.927e-265 829.0
PYH2_k127_119768_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003775 299.0
PYH2_k127_119768_2 YceI-like domain - - - 0.0000000000000000000000000000000000001264 149.0
PYH2_k127_119768_3 peroxiredoxin activity - - - 0.000000000000000000000000004715 126.0
PYH2_k127_119768_4 Thioredoxin-like - - - 0.000000000000000001563 98.0
PYH2_k127_119768_5 Thiamine-binding protein - - - 0.00000000000002565 77.0
PYH2_k127_119768_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00009891 54.0
PYH2_k127_1204093_0 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 7.781e-212 688.0
PYH2_k127_1204093_1 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 415.0
PYH2_k127_1204093_10 cheY-homologous receiver domain - - - 0.00000000000000000000000000000005596 131.0
PYH2_k127_1204093_11 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000773 77.0
PYH2_k127_1204093_12 NusG domain II - - - 0.000000000006831 78.0
PYH2_k127_1204093_13 PFAM Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.00001372 55.0
PYH2_k127_1204093_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000001062 251.0
PYH2_k127_1204093_3 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000009167 250.0
PYH2_k127_1204093_4 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000004696 237.0
PYH2_k127_1204093_5 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000008353 216.0
PYH2_k127_1204093_6 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000114 194.0
PYH2_k127_1204093_7 molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000003917 185.0
PYH2_k127_1204093_8 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000008445 180.0
PYH2_k127_1204093_9 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000002621 137.0
PYH2_k127_1238821_0 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 288.0
PYH2_k127_1238821_1 ResB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001042 287.0
PYH2_k127_1238821_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
PYH2_k127_1238821_3 YCII-related domain - - - 0.00000000000000000000000000007684 117.0
PYH2_k127_1238821_4 Protein of unknown function (DUF4007) - - - 0.0000000000004187 73.0
PYH2_k127_1238821_5 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000004913 61.0
PYH2_k127_1249881_0 Ftsk_gamma K03466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 487.0
PYH2_k127_1249881_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 386.0
PYH2_k127_1249881_2 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.0000000000000000000000000000000000001642 143.0
PYH2_k127_1249881_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000005509 88.0
PYH2_k127_1249881_4 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00003487 47.0
PYH2_k127_1249881_5 Transcriptional regulator - - - 0.0001792 48.0
PYH2_k127_125874_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1189.0
PYH2_k127_125874_1 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 616.0
PYH2_k127_125874_10 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000004394 222.0
PYH2_k127_125874_11 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000005049 221.0
PYH2_k127_125874_12 3-beta hydroxysteroid dehydrogenase isomerase K21793 - - 0.00000000000000000000000000000000000000000000001488 193.0
PYH2_k127_125874_13 regulation of response to stimulus K01126,K21449 - 3.1.4.46 0.000000000000000000000000000000000000000000009079 187.0
PYH2_k127_125874_14 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001741 168.0
PYH2_k127_125874_15 Flagellar hook protein flgE - - - 0.000000000000000000000000000000000000000004277 179.0
PYH2_k127_125874_16 PAP2 superfamily - - - 0.000000000000000000000000000000004021 140.0
PYH2_k127_125874_17 Smr domain - - - 0.0000000000000000000000000000000363 132.0
PYH2_k127_125874_18 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.000000000000000000000000006398 121.0
PYH2_k127_125874_19 CAAX protease self-immunity - - - 0.000000000000000001249 99.0
PYH2_k127_125874_2 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 580.0
PYH2_k127_125874_20 Putative prokaryotic signal transducing protein - - - 0.0000000000001549 73.0
PYH2_k127_125874_21 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000004826 70.0
PYH2_k127_125874_3 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 352.0
PYH2_k127_125874_4 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 314.0
PYH2_k127_125874_5 SNARE associated Golgi protein K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 308.0
PYH2_k127_125874_6 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 321.0
PYH2_k127_125874_7 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002514 293.0
PYH2_k127_125874_8 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007875 278.0
PYH2_k127_125874_9 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002428 239.0
PYH2_k127_1304944_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.585e-290 911.0
PYH2_k127_1304944_1 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 478.0
PYH2_k127_1304944_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 319.0
PYH2_k127_1304944_3 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000008905 157.0
PYH2_k127_1304944_4 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000001574 147.0
PYH2_k127_1304944_5 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000004763 123.0
PYH2_k127_1304944_6 4Fe-4S binding domain - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000003095 93.0
PYH2_k127_1304944_7 Tetratricopeptide repeat - - - 0.00000000001099 79.0
PYH2_k127_1304944_8 PFAM Creatininase K01470 - 3.5.2.10 0.0000000008363 60.0
PYH2_k127_1326424_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1099.0
PYH2_k127_1326424_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.143e-300 949.0
PYH2_k127_1326424_10 regulator - - - 0.00000000000000000000000000000000000000000000000007906 201.0
PYH2_k127_1326424_11 TPR repeat - - - 0.00000000000000000000000000000000000000000000000008744 195.0
PYH2_k127_1326424_12 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000003972 184.0
PYH2_k127_1326424_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000004145 198.0
PYH2_k127_1326424_14 PFAM response regulator receiver K03413 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000003318 151.0
PYH2_k127_1326424_15 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000000000000007177 144.0
PYH2_k127_1326424_16 Lysin motif - - - 0.000000000000000000000000000000000000913 153.0
PYH2_k127_1326424_17 Chemotaxis protein CheA K03407 - 2.7.13.3 0.00000000000000000000000000000000001408 146.0
PYH2_k127_1326424_18 Protein of unknown function (DUF1178) - - - 0.0000000000000000000001674 100.0
PYH2_k127_1326424_19 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000003159 110.0
PYH2_k127_1326424_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 473.0
PYH2_k127_1326424_20 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000001539 92.0
PYH2_k127_1326424_21 Hsp20/alpha crystallin family K13993 - - 0.0000000000000001633 87.0
PYH2_k127_1326424_22 Two component signalling adaptor domain K03408 - - 0.00000000009339 69.0
PYH2_k127_1326424_23 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0006768 50.0
PYH2_k127_1326424_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 443.0
PYH2_k127_1326424_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
PYH2_k127_1326424_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 301.0
PYH2_k127_1326424_6 transmembrane signaling receptor activity K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006521 276.0
PYH2_k127_1326424_7 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000002409 203.0
PYH2_k127_1326424_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000002335 190.0
PYH2_k127_1326424_9 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000004077 205.0
PYH2_k127_1338403_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.241e-207 661.0
PYH2_k127_1338403_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 562.0
PYH2_k127_1338403_10 Alternative locus ID K07491 - - 0.0000000001636 63.0
PYH2_k127_1338403_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000001112 70.0
PYH2_k127_1338403_12 sequence-specific DNA binding K15539 - - 0.00004662 53.0
PYH2_k127_1338403_13 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000551 49.0
PYH2_k127_1338403_2 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 328.0
PYH2_k127_1338403_3 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000015 231.0
PYH2_k127_1338403_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07651 - 2.7.13.3 0.0000000000000000000000000000000000000000001408 184.0
PYH2_k127_1338403_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000001386 158.0
PYH2_k127_1338403_6 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000006171 88.0
PYH2_k127_1338403_7 PFAM GGDEF domain containing protein - - - 0.00000000000006155 87.0
PYH2_k127_1338403_8 NhaP-type Na H and K H - - - 0.00000000001275 77.0
PYH2_k127_1338403_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000001945 74.0
PYH2_k127_1344295_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 523.0
PYH2_k127_1344295_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 473.0
PYH2_k127_1344295_10 Tetratricopeptide repeat - - - 0.000001078 62.0
PYH2_k127_1344295_2 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 463.0
PYH2_k127_1344295_3 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 434.0
PYH2_k127_1344295_4 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 240.0
PYH2_k127_1344295_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000004803 185.0
PYH2_k127_1344295_6 Flagellar hook protein flgE - - - 0.000000000000000000000000000002854 140.0
PYH2_k127_1344295_7 Tetratricopeptide repeat - - - 0.000000000000000000000004433 119.0
PYH2_k127_1344295_8 Response regulator receiver K02485 - - 0.000000000000008687 81.0
PYH2_k127_1344295_9 Tetratricopeptide repeat - - - 0.000000000009416 78.0
PYH2_k127_1385003_0 acetyl-CoA carboxylase, biotin carboxylase K01965 - 6.4.1.3 3.949e-236 737.0
PYH2_k127_1385003_1 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 2.22e-230 751.0
PYH2_k127_1385003_2 PFAM ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 601.0
PYH2_k127_1385003_3 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 349.0
PYH2_k127_1385003_4 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 275.0
PYH2_k127_1385003_5 Conserved carboxylase domain K01958 - 6.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001623 252.0
PYH2_k127_1411360_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 606.0
PYH2_k127_1411360_1 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0019808,GO:0019809,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 415.0
PYH2_k127_1411360_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 347.0
PYH2_k127_1411360_3 GHKL domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003133 292.0
PYH2_k127_1411360_4 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000003665 184.0
PYH2_k127_1411360_5 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000004664 179.0
PYH2_k127_1411360_6 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000006336 143.0
PYH2_k127_1411360_7 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000001072 142.0
PYH2_k127_1411360_8 PFAM AzlC family protein - - - 0.00000000000000000000000000004337 130.0
PYH2_k127_1411360_9 Domain of unknown function DUF302 - - - 0.00000000002627 67.0
PYH2_k127_1425595_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004766 571.0
PYH2_k127_1425595_1 surface antigen (D15) K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 486.0
PYH2_k127_1425595_11 Protein of unknown function (DUF2905) - - - 0.0000000000000001575 83.0
PYH2_k127_1425595_12 Outer membrane protein (OmpH-like) K06142 - - 0.00000000009055 70.0
PYH2_k127_1425595_13 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.000008955 55.0
PYH2_k127_1425595_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 384.0
PYH2_k127_1425595_3 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 325.0
PYH2_k127_1425595_4 Udp N-acetylglucosamine O-acyltransferase; Domain 2 K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 310.0
PYH2_k127_1425595_5 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 258.0
PYH2_k127_1425595_6 OmpA family K02557 - - 0.000000000000000000000000000000000000000000000000000001659 199.0
PYH2_k127_1425595_7 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000002864 194.0
PYH2_k127_1425595_8 Zn-dependent hydrolases of the - - - 0.000000000000000000000000000000000000000000000000006563 194.0
PYH2_k127_1425595_9 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000001507 115.0
PYH2_k127_1487004_0 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 394.0
PYH2_k127_1487004_1 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000005469 209.0
PYH2_k127_1487004_2 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000007709 198.0
PYH2_k127_1487004_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000001913 161.0
PYH2_k127_1506185_0 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000009111 151.0
PYH2_k127_1506185_1 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000003897 116.0
PYH2_k127_1506185_2 Permease, YjgP YjgQ - - - 0.00000000002908 75.0
PYH2_k127_1506185_3 PA14 domain - - - 0.000000009692 64.0
PYH2_k127_1506185_4 PFAM CheW domain protein K03408 - - 0.00003175 51.0
PYH2_k127_1527434_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 533.0
PYH2_k127_1527434_1 COG0618 Exopolyphosphatase-related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 297.0
PYH2_k127_1527434_2 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 291.0
PYH2_k127_1527434_3 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000006045 246.0
PYH2_k127_1527434_4 Pfam Anion-transporting ATPase K01551,K19171 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000006168 236.0
PYH2_k127_1527434_5 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000009428 197.0
PYH2_k127_1527434_6 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000004742 162.0
PYH2_k127_1527434_7 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000001137 105.0
PYH2_k127_1527434_8 PFAM ApbE family K09740 - - 0.0000003893 63.0
PYH2_k127_1529577_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 460.0
PYH2_k127_1529577_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 342.0
PYH2_k127_1529577_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 334.0
PYH2_k127_1529577_3 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 295.0
PYH2_k127_1529577_4 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000005254 217.0
PYH2_k127_1529577_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000005347 144.0
PYH2_k127_1529577_6 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000004503 111.0
PYH2_k127_1529577_7 energy transducer activity K03646,K03832 - - 0.000000000000000000000004354 112.0
PYH2_k127_1702488_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1116.0
PYH2_k127_1702488_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 429.0
PYH2_k127_1702488_10 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000006961 112.0
PYH2_k127_1702488_11 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000004752 94.0
PYH2_k127_1702488_12 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.000000000008377 75.0
PYH2_k127_1702488_14 cellulose binding K07279 - - 0.0005807 50.0
PYH2_k127_1702488_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 376.0
PYH2_k127_1702488_3 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 339.0
PYH2_k127_1702488_4 4Fe-4S binding domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002778 259.0
PYH2_k127_1702488_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000001543 226.0
PYH2_k127_1702488_6 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000009053 219.0
PYH2_k127_1702488_7 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000005687 215.0
PYH2_k127_1702488_8 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000000002681 156.0
PYH2_k127_1702488_9 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000001874 127.0
PYH2_k127_1820145_0 A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
PYH2_k127_1820145_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 259.0
PYH2_k127_1820145_2 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000001497 228.0
PYH2_k127_1820145_3 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.0000000000000000000000000000001124 132.0
PYH2_k127_1820145_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000006074 112.0
PYH2_k127_1820145_5 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000003341 87.0
PYH2_k127_1820145_6 - - - - 0.00000000000004652 84.0
PYH2_k127_1885045_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1327.0
PYH2_k127_1885045_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.021e-216 692.0
PYH2_k127_1885045_10 Recombination protein O C terminal K03584 - - 0.00000000000000004356 95.0
PYH2_k127_1885045_11 - - - - 0.00000000000002366 77.0
PYH2_k127_1885045_13 Domain of unknown function (DUF4115) - - - 0.0000000002511 70.0
PYH2_k127_1885045_14 Cytochrome c - - - 0.0004156 47.0
PYH2_k127_1885045_2 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 626.0
PYH2_k127_1885045_3 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 511.0
PYH2_k127_1885045_4 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 426.0
PYH2_k127_1885045_5 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 340.0
PYH2_k127_1885045_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002766 283.0
PYH2_k127_1885045_7 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000063 185.0
PYH2_k127_1885045_8 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000006823 171.0
PYH2_k127_1885045_9 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000009425 155.0
PYH2_k127_1913535_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 7.521e-283 886.0
PYH2_k127_1913535_1 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 1.907e-202 640.0
PYH2_k127_1913535_10 Short C-terminal domain K08982 - - 0.000000000005994 69.0
PYH2_k127_1913535_11 Protein of unknown function (DUF1761) - - - 0.0000000009595 64.0
PYH2_k127_1913535_2 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 415.0
PYH2_k127_1913535_3 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 396.0
PYH2_k127_1913535_4 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
PYH2_k127_1913535_5 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009666 258.0
PYH2_k127_1913535_6 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000009153 213.0
PYH2_k127_1913535_7 - - - - 0.000000000000000000001975 100.0
PYH2_k127_1913535_9 - - - - 0.0000000000000147 80.0
PYH2_k127_193924_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 406.0
PYH2_k127_193924_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
PYH2_k127_193924_3 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000004099 211.0
PYH2_k127_193924_4 - - - - 0.0000000000000000000000000000000000000003279 163.0
PYH2_k127_193924_5 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000674 146.0
PYH2_k127_1943111_0 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001048 388.0
PYH2_k127_1943111_1 Periplasmic binding protein K07121 - - 0.0000000000000000000000000000000000000000000000000000003196 216.0
PYH2_k127_1943111_2 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000001266 175.0
PYH2_k127_198428_0 P2 response regulator binding domain K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 338.0
PYH2_k127_198428_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 310.0
PYH2_k127_198428_10 Glycine cleavage H-protein K02437 - - 0.000000000000000000000004652 110.0
PYH2_k127_198428_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 310.0
PYH2_k127_198428_3 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000004152 268.0
PYH2_k127_198428_4 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 255.0
PYH2_k127_198428_5 Belongs to the LarC family K09121 - 4.99.1.12 0.0000000000000000000000000000000000000000000000000000000000000000004586 249.0
PYH2_k127_198428_6 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000001218 237.0
PYH2_k127_198428_7 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.0000000000000000000000000000000000000000000000000000000006619 219.0
PYH2_k127_198428_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000005755 146.0
PYH2_k127_198428_9 CheC-like family K03410 - - 0.000000000000000000000000000001539 130.0
PYH2_k127_2003594_0 DNA polymerase A domain K02335 - 2.7.7.7 6.059e-274 871.0
PYH2_k127_2003594_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 3.439e-212 698.0
PYH2_k127_2003594_10 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.000000000000000000000000000000000000000000000000000000000000000000398 239.0
PYH2_k127_2003594_11 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000004623 211.0
PYH2_k127_2003594_12 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000001213 216.0
PYH2_k127_2003594_13 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000004118 196.0
PYH2_k127_2003594_14 Type I restriction enzyme R protein N terminus (HSDR_N) K07504 - - 0.00000000000000000000000000000331 125.0
PYH2_k127_2003594_15 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000004885 109.0
PYH2_k127_2003594_16 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP - - - 0.000000000000002056 84.0
PYH2_k127_2003594_17 peptidyl-tyrosine sulfation - - - 0.00000002656 66.0
PYH2_k127_2003594_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 614.0
PYH2_k127_2003594_3 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 612.0
PYH2_k127_2003594_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 563.0
PYH2_k127_2003594_5 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 491.0
PYH2_k127_2003594_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 398.0
PYH2_k127_2003594_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 381.0
PYH2_k127_2003594_8 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 365.0
PYH2_k127_2003594_9 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003526 254.0
PYH2_k127_2006149_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1026.0
PYH2_k127_2006149_1 PFAM aminotransferase, class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 482.0
PYH2_k127_2006149_10 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000001447 250.0
PYH2_k127_2006149_11 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003201 244.0
PYH2_k127_2006149_12 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001944 227.0
PYH2_k127_2006149_13 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000005641 177.0
PYH2_k127_2006149_14 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000007737 184.0
PYH2_k127_2006149_15 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000001354 177.0
PYH2_k127_2006149_16 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000003913 168.0
PYH2_k127_2006149_17 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000003863 143.0
PYH2_k127_2006149_18 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000005161 141.0
PYH2_k127_2006149_19 Amidohydrolase - - - 0.0000000000000000000000000004625 123.0
PYH2_k127_2006149_2 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 406.0
PYH2_k127_2006149_20 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000388 113.0
PYH2_k127_2006149_21 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000005336 109.0
PYH2_k127_2006149_22 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02487 - - 0.00000000000000000005662 98.0
PYH2_k127_2006149_23 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000003498 79.0
PYH2_k127_2006149_24 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000005818 56.0
PYH2_k127_2006149_25 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00005442 57.0
PYH2_k127_2006149_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 392.0
PYH2_k127_2006149_4 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 381.0
PYH2_k127_2006149_5 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 347.0
PYH2_k127_2006149_6 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 314.0
PYH2_k127_2006149_7 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004062 311.0
PYH2_k127_2006149_8 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006296 279.0
PYH2_k127_2006149_9 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000286 278.0
PYH2_k127_2018835_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1607.0
PYH2_k127_2018835_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 297.0
PYH2_k127_2018835_2 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000006109 233.0
PYH2_k127_2018835_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000006232 224.0
PYH2_k127_2018835_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.000000000000000000000000000000000000000000000000006578 182.0
PYH2_k127_2018835_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000007078 169.0
PYH2_k127_2018835_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000721 160.0
PYH2_k127_2018835_7 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.00000000008752 65.0
PYH2_k127_2025145_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K00170 - 1.2.7.1 1.211e-299 940.0
PYH2_k127_2025145_1 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 5.97e-264 829.0
PYH2_k127_2025145_10 ferredoxin K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 348.0
PYH2_k127_2025145_11 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 304.0
PYH2_k127_2025145_12 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001332 284.0
PYH2_k127_2025145_13 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 264.0
PYH2_k127_2025145_14 Cytochrome b5-like Heme/Steroid binding domain K07245,K14166 - - 0.0000000000000000000000000000000000000000000000000000000000000003127 233.0
PYH2_k127_2025145_15 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000001516 215.0
PYH2_k127_2025145_16 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.0000000000000000000000000000000000000000000000000000001406 205.0
PYH2_k127_2025145_17 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000001961 178.0
PYH2_k127_2025145_18 PFAM Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000003517 159.0
PYH2_k127_2025145_19 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000006795 147.0
PYH2_k127_2025145_2 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.38e-241 758.0
PYH2_k127_2025145_20 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000001912 143.0
PYH2_k127_2025145_21 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.00000000000000000000000000000003217 132.0
PYH2_k127_2025145_22 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000006367 114.0
PYH2_k127_2025145_23 QueT transporter - - - 0.0000000000000000000007077 103.0
PYH2_k127_2025145_24 Thioesterase superfamily - - - 0.0000000000000000004711 94.0
PYH2_k127_2025145_25 Integrin alpha (beta-propellor repeats). - - - 0.0000000003082 72.0
PYH2_k127_2025145_26 - - - - 0.0001288 50.0
PYH2_k127_2025145_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 496.0
PYH2_k127_2025145_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 447.0
PYH2_k127_2025145_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 424.0
PYH2_k127_2025145_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 400.0
PYH2_k127_2025145_7 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 380.0
PYH2_k127_2025145_8 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 372.0
PYH2_k127_2025145_9 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 369.0
PYH2_k127_209422_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.03e-223 725.0
PYH2_k127_209422_1 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 446.0
PYH2_k127_209422_10 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000009506 226.0
PYH2_k127_209422_11 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000000000005325 145.0
PYH2_k127_209422_12 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.000000000000000000000000000005512 128.0
PYH2_k127_209422_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 418.0
PYH2_k127_209422_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 394.0
PYH2_k127_209422_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 402.0
PYH2_k127_209422_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 362.0
PYH2_k127_209422_6 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 366.0
PYH2_k127_209422_7 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 343.0
PYH2_k127_209422_8 cheY-homologous receiver domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
PYH2_k127_209422_9 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000006438 226.0
PYH2_k127_213367_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1091.0
PYH2_k127_213367_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 3.7e-227 722.0
PYH2_k127_213367_10 PFAM Molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001876 235.0
PYH2_k127_213367_11 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000008472 245.0
PYH2_k127_213367_12 regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
PYH2_k127_213367_13 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000003148 197.0
PYH2_k127_213367_14 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000005776 167.0
PYH2_k127_213367_15 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000009843 177.0
PYH2_k127_213367_16 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000004585 122.0
PYH2_k127_213367_17 Putative regulatory protein - - - 0.00000000000457 68.0
PYH2_k127_213367_18 RNA-binding protein - - - 0.0000004006 56.0
PYH2_k127_213367_2 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 590.0
PYH2_k127_213367_3 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 447.0
PYH2_k127_213367_4 phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 427.0
PYH2_k127_213367_5 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 365.0
PYH2_k127_213367_6 Two component, sigma54 specific, transcriptional regulator, Fis family K07712,K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 330.0
PYH2_k127_213367_7 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 296.0
PYH2_k127_213367_8 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006814 265.0
PYH2_k127_213367_9 Formate dehydrogenase N, transmembrane K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 261.0
PYH2_k127_2156535_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000238 256.0
PYH2_k127_2156535_1 DivIVA protein K04074 - - 0.0000000000000000000000000000000001323 139.0
PYH2_k127_2156535_2 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000000001778 136.0
PYH2_k127_2156535_3 Belongs to the UPF0235 family K09131 - - 0.0000000000000001502 85.0
PYH2_k127_2156535_4 YGGT family K02221 - - 0.00000000000001871 77.0
PYH2_k127_2156535_5 Kelch - - - 0.00000000000002319 87.0
PYH2_k127_2156535_6 Peptidase MA superfamily - - - 0.000000001797 70.0
PYH2_k127_2156535_7 PEGA domain - - - 0.00002038 57.0
PYH2_k127_2199100_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 542.0
PYH2_k127_2199100_1 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000000006914 245.0
PYH2_k127_2199100_2 - - - - 0.000000000000000000000000000000000000000000000000001037 202.0
PYH2_k127_2199100_3 - - - - 0.000000000000000000000000000000000000000000000007977 176.0
PYH2_k127_2199100_4 - - - - 0.00000000000000000000000000000001987 139.0
PYH2_k127_2238782_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 7.23e-210 680.0
PYH2_k127_2238782_1 IMP dehydrogenase / GMP reductase domain K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 517.0
PYH2_k127_2238782_10 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000001785 165.0
PYH2_k127_2238782_11 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000001868 148.0
PYH2_k127_2238782_12 Sporulation and spore germination - - - 0.0000000000000000000001169 108.0
PYH2_k127_2238782_13 RDD family - - - 0.00000000000000001373 91.0
PYH2_k127_2238782_14 Transmembrane and - - - 0.000000000000003778 86.0
PYH2_k127_2238782_15 Belongs to the pirin family K06911 - - 0.00000006964 54.0
PYH2_k127_2238782_16 - - - - 0.000001036 51.0
PYH2_k127_2238782_2 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 347.0
PYH2_k127_2238782_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 288.0
PYH2_k127_2238782_4 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001838 268.0
PYH2_k127_2238782_5 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000002659 229.0
PYH2_k127_2238782_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000002146 203.0
PYH2_k127_2238782_7 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000002153 189.0
PYH2_k127_2238782_8 Protein of unknown function (DUF3187) - - - 0.0000000000000000000000000000000000000000005111 171.0
PYH2_k127_2238782_9 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000001363 168.0
PYH2_k127_2341141_0 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 377.0
PYH2_k127_2341141_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 340.0
PYH2_k127_2341141_10 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000274 166.0
PYH2_k127_2341141_11 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000336 158.0
PYH2_k127_2341141_12 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000005418 118.0
PYH2_k127_2341141_13 all-trans-retinol 13,14-reductase activity - - - 0.00001027 58.0
PYH2_k127_2341141_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 340.0
PYH2_k127_2341141_3 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 333.0
PYH2_k127_2341141_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 330.0
PYH2_k127_2341141_5 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 260.0
PYH2_k127_2341141_6 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004428 255.0
PYH2_k127_2341141_7 PFAM Stage II sporulation K06381 - - 0.000000000000000000000000000000000000000000000000000000000001478 224.0
PYH2_k127_2341141_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000004069 200.0
PYH2_k127_2341141_9 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000001767 210.0
PYH2_k127_2364788_0 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000007482 232.0
PYH2_k127_2364788_1 domain protein - - - 0.00000000000000000000000000000000000000000000000000000003148 211.0
PYH2_k127_2364788_2 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.00000000000000000000000006741 124.0
PYH2_k127_2364788_3 Periplasmic copper-binding protein (NosD) - - - 0.0000000000008255 72.0
PYH2_k127_241168_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000003165 205.0
PYH2_k127_241168_1 cell redox homeostasis K03671 - - 0.00000000000008506 77.0
PYH2_k127_241168_2 serine threonine-protein phosphatase K04460 GO:0003674,GO:0003824,GO:0004721,GO:0004722,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005654,GO:0005737,GO:0005783,GO:0005789,GO:0005829,GO:0005911,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006913,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009314,GO:0009416,GO:0009506,GO:0009628,GO:0009639,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010017,GO:0010019,GO:0010035,GO:0010038,GO:0010380,GO:0012505,GO:0016020,GO:0016021,GO:0016311,GO:0016604,GO:0016607,GO:0016787,GO:0016788,GO:0016791,GO:0019222,GO:0019538,GO:0023052,GO:0030054,GO:0030176,GO:0031090,GO:0031224,GO:0031227,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031965,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0031984,GO:0036211,GO:0042175,GO:0042221,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044432,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046686,GO:0046906,GO:0046907,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051169,GO:0051171,GO:0051172,GO:0051179,GO:0051193,GO:0051195,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055044,GO:0065007,GO:0070013,GO:0071214,GO:0071478,GO:0071482,GO:0071489,GO:0071704,GO:0090056,GO:0097159,GO:0098827,GO:0104004,GO:0140096,GO:1901363,GO:1901401,GO:1901402,GO:1901463,GO:1901464,GO:1901564,GO:1902325 3.1.3.16 0.00001983 49.0
PYH2_k127_241168_3 SurA N-terminal domain K01802,K03770 - 5.2.1.8 0.00006288 56.0
PYH2_k127_241492_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 331.0
PYH2_k127_241492_1 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000884 66.0
PYH2_k127_2434529_0 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 327.0
PYH2_k127_2434529_1 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000000006336 171.0
PYH2_k127_2434529_2 - - - - 0.00000000000000000000000000000007955 133.0
PYH2_k127_2434529_3 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000002424 91.0
PYH2_k127_2434529_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00003771 48.0
PYH2_k127_2599710_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 545.0
PYH2_k127_2599710_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 326.0
PYH2_k127_2599710_2 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000004294 172.0
PYH2_k127_2642385_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 612.0
PYH2_k127_2642385_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
PYH2_k127_2642385_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 387.0
PYH2_k127_2642385_3 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001549 279.0
PYH2_k127_2642385_4 HEAT repeats - - - 0.00000000000000000000000000000002349 145.0
PYH2_k127_2642385_5 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.0000000004379 64.0
PYH2_k127_2642385_6 deoxyhypusine monooxygenase activity - - - 0.000009376 56.0
PYH2_k127_269872_0 Protein of unknown function, DUF255 K06888 - - 5.25e-198 634.0
PYH2_k127_269872_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 578.0
PYH2_k127_269872_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 381.0
PYH2_k127_269872_3 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 319.0
PYH2_k127_269872_4 Lycopene cyclase protein K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000005626 275.0
PYH2_k127_269872_5 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000000000000001092 197.0
PYH2_k127_269872_6 Protein of unknown function (DUF429) - - - 0.000000000000000000000000000000000000000000000002799 188.0
PYH2_k127_269872_7 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000001348 153.0
PYH2_k127_269872_8 Putative TM nitroreductase - - - 0.000000000000000000000000000000006961 134.0
PYH2_k127_2881730_0 Glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000174 225.0
PYH2_k127_2881730_1 PFAM glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000034 216.0
PYH2_k127_2881730_2 PFAM glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000005344 215.0
PYH2_k127_2881730_3 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000002663 211.0
PYH2_k127_2881730_4 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000001809 176.0
PYH2_k127_2881730_5 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000002213 145.0
PYH2_k127_2881730_6 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.00000000000000000000000000002172 131.0
PYH2_k127_2910791_0 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007043 277.0
PYH2_k127_2910791_1 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008529 250.0
PYH2_k127_2910791_2 ABC 3 transport family K09816 - - 0.000000000000000000000000000000000000000000000000000008626 197.0
PYH2_k127_2937093_0 CBS domain containing protein K00974 - 2.7.7.72 3.26e-221 712.0
PYH2_k127_2937093_1 Domain of unknown function (DUF2703) - - - 0.0000000000000000000000000000000000000006341 152.0
PYH2_k127_2977352_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 368.0
PYH2_k127_2977352_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 338.0
PYH2_k127_2977352_2 ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 336.0
PYH2_k127_2977352_3 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 308.0
PYH2_k127_2977352_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000000000000003297 205.0
PYH2_k127_2977352_5 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000006816 120.0
PYH2_k127_2977352_6 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000002274 90.0
PYH2_k127_3072084_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.666e-265 831.0
PYH2_k127_3072084_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 513.0
PYH2_k127_3072084_10 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000003976 211.0
PYH2_k127_3072084_11 PFAM FMN-binding domain - - - 0.000000000000000000000000000000000000000000000000006048 192.0
PYH2_k127_3072084_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000001572 167.0
PYH2_k127_3072084_13 CcmB protein K02194 - - 0.0000000000000000000000000000000000000002249 159.0
PYH2_k127_3072084_14 PFAM Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000001372 146.0
PYH2_k127_3072084_15 cell redox homeostasis K02199 - - 0.00000000000000000000000000000000003705 141.0
PYH2_k127_3072084_16 Tetratricopeptide repeat - - - 0.00000000000000000000001299 113.0
PYH2_k127_3072084_17 Helix-turn-helix domain - - - 0.0000000000000000000002785 105.0
PYH2_k127_3072084_18 PASTA K12132 - 2.7.11.1 0.000000000000000000005704 108.0
PYH2_k127_3072084_19 DUF218 domain - - - 0.000000000000002189 87.0
PYH2_k127_3072084_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 314.0
PYH2_k127_3072084_21 - - - - 0.000002271 54.0
PYH2_k127_3072084_3 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 295.0
PYH2_k127_3072084_4 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000977 280.0
PYH2_k127_3072084_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001045 281.0
PYH2_k127_3072084_6 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002899 272.0
PYH2_k127_3072084_7 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000008081 244.0
PYH2_k127_3072084_8 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000008167 207.0
PYH2_k127_3072084_9 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000003558 199.0
PYH2_k127_3087311_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 325.0
PYH2_k127_3087311_1 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000004599 174.0
PYH2_k127_3087311_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000006093 126.0
PYH2_k127_3087311_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000001343 87.0
PYH2_k127_3129994_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007677 503.0
PYH2_k127_3129994_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 421.0
PYH2_k127_3129994_11 Thioredoxin-like - - - 0.0000000000007173 75.0
PYH2_k127_3129994_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000003274 216.0
PYH2_k127_3129994_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000000002615 196.0
PYH2_k127_3129994_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000008976 177.0
PYH2_k127_3129994_5 Belongs to the TrpC family K01609 GO:0000162,GO:0000287,GO:0003674,GO:0003824,GO:0004425,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016020,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019752,GO:0030312,GO:0034641,GO:0040007,GO:0042401,GO:0042430,GO:0042435,GO:0043167,GO:0043169,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046219,GO:0046391,GO:0046394,GO:0046483,GO:0046872,GO:0071704,GO:0071944,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.1.1.48 0.00000000000000000000000000000000000000000000000295 181.0
PYH2_k127_3129994_6 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000001967 162.0
PYH2_k127_3129994_7 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000005626 127.0
PYH2_k127_3129994_8 Histidine kinase - - - 0.00000000000000000000000002675 115.0
PYH2_k127_3129994_9 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000001068 89.0
PYH2_k127_3164780_0 biotin carboxylase activity K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006062 394.0
PYH2_k127_3164780_1 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000003758 157.0
PYH2_k127_3311197_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.038e-223 705.0
PYH2_k127_3311197_1 Uncharacterized conserved protein (DUF2075) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 389.0
PYH2_k127_3311197_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000000000003884 136.0
PYH2_k127_3311197_3 Plasmid stability protein K21495 - - 0.00000000000004535 74.0
PYH2_k127_3311197_5 - - - - 0.00007729 48.0
PYH2_k127_3412419_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 449.0
PYH2_k127_3412419_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000003725 160.0
PYH2_k127_3412419_2 PFAM BioY K03523 - - 0.00000000000000000000000000000008956 130.0
PYH2_k127_3412419_3 diguanylate cyclase - - - 0.0000000000000000003481 100.0
PYH2_k127_3458622_0 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 434.0
PYH2_k127_3458622_1 GDP-mannose 4,6 dehydratase K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 360.0
PYH2_k127_3458622_10 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000146 215.0
PYH2_k127_3458622_11 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
PYH2_k127_3458622_12 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K03273,K15669 - 2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000000000007854 181.0
PYH2_k127_3458622_13 Methyltransferase domain - - - 0.000000000000000000000000000000001561 139.0
PYH2_k127_3458622_14 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000005247 128.0
PYH2_k127_3458622_15 Polysaccharide biosynthesis C-terminal domain K03328 - - 0.000000000000000000000000000001482 139.0
PYH2_k127_3458622_16 Glycosyl transferases group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.00000000000000000002261 104.0
PYH2_k127_3458622_17 methyltransferase K16215 - 2.1.1.243 0.000000000000000004973 93.0
PYH2_k127_3458622_18 Methyltransferase - - - 0.00000000000000001829 91.0
PYH2_k127_3458622_19 Glycosyl transferases group 1 - - - 0.000000000000008026 84.0
PYH2_k127_3458622_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 356.0
PYH2_k127_3458622_20 - - - - 0.000004459 59.0
PYH2_k127_3458622_21 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0001601 54.0
PYH2_k127_3458622_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 309.0
PYH2_k127_3458622_4 dTDP-4-dehydrorhamnose reductase activity K00067,K01790,K19997 - 1.1.1.133,5.1.3.13,5.1.3.26 0.00000000000000000000000000000000000000000000000000000000000000000000002368 269.0
PYH2_k127_3458622_5 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005004 252.0
PYH2_k127_3458622_6 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000001811 247.0
PYH2_k127_3458622_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
PYH2_k127_3458622_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000001324 230.0
PYH2_k127_3458622_9 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000001486 231.0
PYH2_k127_3631570_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 443.0
PYH2_k127_3631570_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007737 392.0
PYH2_k127_3631570_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000001259 212.0
PYH2_k127_3631570_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000004442 128.0
PYH2_k127_3631570_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000001425 70.0
PYH2_k127_3660027_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 565.0
PYH2_k127_3660027_1 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000083 567.0
PYH2_k127_3660027_10 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000003725 99.0
PYH2_k127_3660027_11 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000003316 67.0
PYH2_k127_3660027_12 - - - - 0.0000007855 53.0
PYH2_k127_3660027_2 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 466.0
PYH2_k127_3660027_3 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 475.0
PYH2_k127_3660027_4 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 357.0
PYH2_k127_3660027_5 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001362 249.0
PYH2_k127_3660027_6 Class III cytochrome C family - - - 0.000000000000000000000000000000000000000000000000006697 186.0
PYH2_k127_3660027_7 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000008144 151.0
PYH2_k127_3660027_8 TIGRFAM diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000001654 137.0
PYH2_k127_3660027_9 - - - - 0.000000000000000000000000000004911 125.0
PYH2_k127_371741_0 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000005585 170.0
PYH2_k127_3766097_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 400.0
PYH2_k127_3766097_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000006592 136.0
PYH2_k127_3766515_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 520.0
PYH2_k127_3766515_1 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 498.0
PYH2_k127_3766515_2 Thermophilic metalloprotease (M29) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001178 292.0
PYH2_k127_3766515_3 Domain of unknown function (DUF4390) - - - 0.00000000000002126 81.0
PYH2_k127_3766515_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000001117 71.0
PYH2_k127_3790079_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 9.369e-272 863.0
PYH2_k127_3790079_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 549.0
PYH2_k127_3790079_10 GTPase activity K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 292.0
PYH2_k127_3790079_11 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002628 269.0
PYH2_k127_3790079_12 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000001235 240.0
PYH2_k127_3790079_13 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000112 213.0
PYH2_k127_3790079_14 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000001211 188.0
PYH2_k127_3790079_15 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000001531 178.0
PYH2_k127_3790079_16 - - - - 0.00000000000000000000000000000000000000000000007332 173.0
PYH2_k127_3790079_17 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000001042 174.0
PYH2_k127_3790079_18 Nitroreductase family - - - 0.000000000000000000000000000000000000000000002366 170.0
PYH2_k127_3790079_19 response regulator - - - 0.00000000000000000000000000000000000000002246 154.0
PYH2_k127_3790079_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 381.0
PYH2_k127_3790079_20 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000009215 153.0
PYH2_k127_3790079_21 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000005893 151.0
PYH2_k127_3790079_22 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC K09667 - 2.4.1.255 0.000000000000000000008184 101.0
PYH2_k127_3790079_23 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin K00180 - 1.2.7.8 0.000000005931 61.0
PYH2_k127_3790079_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 379.0
PYH2_k127_3790079_4 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 376.0
PYH2_k127_3790079_5 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 377.0
PYH2_k127_3790079_6 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 361.0
PYH2_k127_3790079_7 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 366.0
PYH2_k127_3790079_8 Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 361.0
PYH2_k127_3790079_9 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 303.0
PYH2_k127_3810911_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.332e-282 892.0
PYH2_k127_3810911_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 508.0
PYH2_k127_3810911_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 327.0
PYH2_k127_3810911_3 beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003613 276.0
PYH2_k127_3810911_4 CoA binding domain K01740,K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.49 0.000000000000000000000000000000000000000000000888 169.0
PYH2_k127_3810911_5 Type I restriction enzyme R protein N terminus (HSDR_N) K07504 - - 0.000000000000000000000000000000000000007665 148.0
PYH2_k127_3810911_6 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000005728 121.0
PYH2_k127_3810911_7 DNA-binding transcription factor activity K03892 - - 0.00000000000000003888 94.0
PYH2_k127_3810911_8 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000005324 78.0
PYH2_k127_3810911_9 - - - - 0.00000001969 67.0
PYH2_k127_3818216_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.106e-232 735.0
PYH2_k127_3818216_1 Isocitrate/isopropylmalate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 4.861e-229 715.0
PYH2_k127_3818216_10 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 410.0
PYH2_k127_3818216_11 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 394.0
PYH2_k127_3818216_12 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, alpha region K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 362.0
PYH2_k127_3818216_13 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 343.0
PYH2_k127_3818216_14 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 325.0
PYH2_k127_3818216_15 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
PYH2_k127_3818216_16 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000004433 257.0
PYH2_k127_3818216_17 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000332 258.0
PYH2_k127_3818216_18 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000007702 218.0
PYH2_k127_3818216_19 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
PYH2_k127_3818216_2 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 7.895e-201 640.0
PYH2_k127_3818216_20 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000002626 201.0
PYH2_k127_3818216_21 domain protein K03499 - - 0.00000000000000000000000000000000000000000000000002191 186.0
PYH2_k127_3818216_22 Competence protein K02238 - - 0.000000000000000000000000000002204 139.0
PYH2_k127_3818216_23 succinate dehydrogenase K00241 - - 0.000000000000000000001971 97.0
PYH2_k127_3818216_24 - - - - 0.000000000000000000002678 102.0
PYH2_k127_3818216_25 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000003222 91.0
PYH2_k127_3818216_26 GIY-YIG catalytic domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000002042 89.0
PYH2_k127_3818216_27 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000001873 69.0
PYH2_k127_3818216_28 His Kinase A (phosphoacceptor) domain - - - 0.0000002084 64.0
PYH2_k127_3818216_3 PFAM cation transporter K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 513.0
PYH2_k127_3818216_4 potassium uptake protein TrkH K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 510.0
PYH2_k127_3818216_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 495.0
PYH2_k127_3818216_6 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 472.0
PYH2_k127_3818216_7 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008991 473.0
PYH2_k127_3818216_8 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 456.0
PYH2_k127_3818216_9 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009158 437.0
PYH2_k127_3867890_0 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000000000000000005987 181.0
PYH2_k127_3867890_1 NIL - - - 0.00000000000000000000000000000000000707 141.0
PYH2_k127_3867890_2 Domain of unknown function (DUF4440) - - - 0.0004277 49.0
PYH2_k127_3873812_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 514.0
PYH2_k127_3873812_1 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001155 268.0
PYH2_k127_3873812_2 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000002711 216.0
PYH2_k127_3873812_3 Zn-dependent hydrolases of the - - - 0.000000000000000000000000000000000000000000000000218 182.0
PYH2_k127_3873812_4 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000002075 150.0
PYH2_k127_3873812_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000001536 102.0
PYH2_k127_3873812_6 KR domain K00059 - 1.1.1.100 0.0000000000000001559 79.0
PYH2_k127_3877955_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 312.0
PYH2_k127_3877955_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001238 240.0
PYH2_k127_4046745_0 lysine 2,3-aminomutase activity K01843,K19810 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 561.0
PYH2_k127_4046745_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008794 483.0
PYH2_k127_4046745_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 364.0
PYH2_k127_4046745_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 302.0
PYH2_k127_4046745_4 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007344 272.0
PYH2_k127_4046745_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000000003267 133.0
PYH2_k127_4046745_6 Tetratricopeptide repeat - - - 0.000000000000000000002609 109.0
PYH2_k127_4191448_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 576.0
PYH2_k127_4191448_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 541.0
PYH2_k127_4191448_2 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 447.0
PYH2_k127_4191448_3 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000004878 271.0
PYH2_k127_4232888_0 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1189.0
PYH2_k127_4232888_1 Natural resistance-associated macrophage protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009519 498.0
PYH2_k127_4232888_2 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 427.0
PYH2_k127_4232888_3 impB/mucB/samB family K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 404.0
PYH2_k127_4232888_4 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008814 299.0
PYH2_k127_4232888_5 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000003171 218.0
PYH2_k127_4232888_6 MgtE intracellular N domain K02000,K05847 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000004713 206.0
PYH2_k127_4232888_7 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000004867 105.0
PYH2_k127_4232888_8 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000000000001178 109.0
PYH2_k127_42459_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 510.0
PYH2_k127_42459_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 516.0
PYH2_k127_42459_2 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001978 283.0
PYH2_k127_42459_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009318 284.0
PYH2_k127_42459_4 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000001363 175.0
PYH2_k127_4296849_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008975 252.0
PYH2_k127_4296849_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000002911 228.0
PYH2_k127_4296849_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000005303 144.0
PYH2_k127_4404938_0 Penicillin-binding protein 1A K05366,K21464 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 485.0
PYH2_k127_4404938_1 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 383.0
PYH2_k127_4404938_2 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000002018 121.0
PYH2_k127_4404938_3 denitrification pathway - - - 0.000000000000007028 89.0
PYH2_k127_4484275_0 COG0058 Glucan phosphorylase - - - 7.112e-242 760.0
PYH2_k127_4484275_1 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 568.0
PYH2_k127_4484275_10 Putative glutamine amidotransferase K07114 - - 0.000000000000000000000000000008609 138.0
PYH2_k127_4484275_11 GYD domain - - - 0.0000000000000000000000008819 118.0
PYH2_k127_4484275_12 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000003952 117.0
PYH2_k127_4484275_13 AsmA family K07289,K07290 - - 0.0000000000000022 89.0
PYH2_k127_4484275_14 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000006346 75.0
PYH2_k127_4484275_15 - - - - 0.000000001244 72.0
PYH2_k127_4484275_16 oxidoreductase activity - - - 0.000001296 61.0
PYH2_k127_4484275_2 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 364.0
PYH2_k127_4484275_3 Associated with various cellular activities K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007968 341.0
PYH2_k127_4484275_4 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 275.0
PYH2_k127_4484275_5 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000246 228.0
PYH2_k127_4484275_6 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000007522 211.0
PYH2_k127_4484275_7 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000001056 219.0
PYH2_k127_4484275_8 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000008245 178.0
PYH2_k127_4484275_9 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000000000000006215 169.0
PYH2_k127_4512297_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.021e-239 761.0
PYH2_k127_4512297_1 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 2.18e-200 648.0
PYH2_k127_4512297_10 Uncharacterized protein family, UPF0114 - - - 0.0008049 50.0
PYH2_k127_4512297_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 574.0
PYH2_k127_4512297_3 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 423.0
PYH2_k127_4512297_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 364.0
PYH2_k127_4512297_5 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 370.0
PYH2_k127_4512297_6 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 333.0
PYH2_k127_4512297_7 domain, Protein - - - 0.0000000002976 68.0
PYH2_k127_4512297_8 Thioredoxin - - - 0.000001271 57.0
PYH2_k127_4512297_9 by MetaGeneAnnotator - - - 0.000006057 49.0
PYH2_k127_4524709_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 580.0
PYH2_k127_4524709_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0016485,GO:0016540,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 4.1.1.11 0.00000000000000000000000000000000006673 136.0
PYH2_k127_4524709_2 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000035 95.0
PYH2_k127_4678587_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1243.0
PYH2_k127_4678587_1 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.29e-262 824.0
PYH2_k127_4678587_10 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 355.0
PYH2_k127_4678587_11 HrcA protein C terminal domain K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 321.0
PYH2_k127_4678587_12 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 311.0
PYH2_k127_4678587_13 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009247 257.0
PYH2_k127_4678587_14 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001404 264.0
PYH2_k127_4678587_15 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000003628 246.0
PYH2_k127_4678587_16 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000003162 225.0
PYH2_k127_4678587_17 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000005376 203.0
PYH2_k127_4678587_18 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000738 194.0
PYH2_k127_4678587_19 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000003219 210.0
PYH2_k127_4678587_2 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 3.127e-235 755.0
PYH2_k127_4678587_20 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000482 203.0
PYH2_k127_4678587_21 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000001586 192.0
PYH2_k127_4678587_22 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000006575 189.0
PYH2_k127_4678587_23 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000001272 173.0
PYH2_k127_4678587_24 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000004662 166.0
PYH2_k127_4678587_25 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000183 162.0
PYH2_k127_4678587_26 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000001602 147.0
PYH2_k127_4678587_27 Could be involved in septation K06412 - - 0.00000000000000000000000000000001653 136.0
PYH2_k127_4678587_28 - - - - 0.0000000000000000000000003879 109.0
PYH2_k127_4678587_29 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000004511 101.0
PYH2_k127_4678587_3 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 474.0
PYH2_k127_4678587_30 protein secretion K03116 - - 0.000000000000000003419 85.0
PYH2_k127_4678587_31 regulatory protein, arsR - - - 0.00000000000000000605 86.0
PYH2_k127_4678587_32 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000159 53.0
PYH2_k127_4678587_4 ATPase with chaperone activity K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006938 477.0
PYH2_k127_4678587_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 439.0
PYH2_k127_4678587_6 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 419.0
PYH2_k127_4678587_7 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
PYH2_k127_4678587_8 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 381.0
PYH2_k127_4678587_9 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 372.0
PYH2_k127_4687618_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1156.0
PYH2_k127_4687618_1 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.938e-234 741.0
PYH2_k127_4687618_10 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 302.0
PYH2_k127_4687618_11 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 298.0
PYH2_k127_4687618_12 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 294.0
PYH2_k127_4687618_13 amine dehydrogenase activity K20276 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 316.0
PYH2_k127_4687618_14 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001865 284.0
PYH2_k127_4687618_15 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002544 289.0
PYH2_k127_4687618_16 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000001763 267.0
PYH2_k127_4687618_17 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002707 258.0
PYH2_k127_4687618_18 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000229 235.0
PYH2_k127_4687618_19 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000002097 230.0
PYH2_k127_4687618_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 389.0
PYH2_k127_4687618_20 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000003663 224.0
PYH2_k127_4687618_21 PFAM Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000002183 203.0
PYH2_k127_4687618_22 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000002627 67.0
PYH2_k127_4687618_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 383.0
PYH2_k127_4687618_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003635 376.0
PYH2_k127_4687618_5 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 338.0
PYH2_k127_4687618_6 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 333.0
PYH2_k127_4687618_7 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 320.0
PYH2_k127_4687618_8 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 313.0
PYH2_k127_4687618_9 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 323.0
PYH2_k127_4754025_0 Elongation factor G C-terminus K06207 - - 4.299e-297 921.0
PYH2_k127_4754025_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.659e-206 649.0
PYH2_k127_4754025_10 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000009355 231.0
PYH2_k127_4754025_11 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000005662 212.0
PYH2_k127_4754025_12 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000004826 192.0
PYH2_k127_4754025_13 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000001081 188.0
PYH2_k127_4754025_14 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000003054 154.0
PYH2_k127_4754025_15 Protein of Unknown function (DUF2784) - - - 0.0000000002632 71.0
PYH2_k127_4754025_16 Tetratricopeptide repeat-like domain - - - 0.000000003013 66.0
PYH2_k127_4754025_17 GXGXG motif - - - 0.0007318 42.0
PYH2_k127_4754025_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 7.794e-200 642.0
PYH2_k127_4754025_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 557.0
PYH2_k127_4754025_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 537.0
PYH2_k127_4754025_5 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 399.0
PYH2_k127_4754025_6 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 389.0
PYH2_k127_4754025_7 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 377.0
PYH2_k127_4754025_8 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 368.0
PYH2_k127_4754025_9 GDP-mannose 4,6 dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 353.0
PYH2_k127_4802791_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 566.0
PYH2_k127_4802791_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 394.0
PYH2_k127_4802791_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000003991 231.0
PYH2_k127_4802791_11 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000004181 224.0
PYH2_k127_4802791_12 heptosyltransferase K02841 - - 0.000000000000000000000000000000000000000000000000006127 194.0
PYH2_k127_4802791_13 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000144 181.0
PYH2_k127_4802791_14 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000001082 179.0
PYH2_k127_4802791_15 glycosyl transferase group 1 K20444 - - 0.0000000000000000000000000000000000000001373 163.0
PYH2_k127_4802791_16 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000002191 154.0
PYH2_k127_4802791_17 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000008223 132.0
PYH2_k127_4802791_18 Phospholipid methyltransferase - - - 0.00000000000000000000000001085 117.0
PYH2_k127_4802791_19 transferase activity, transferring glycosyl groups - - - 0.000000000000001401 84.0
PYH2_k127_4802791_2 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 391.0
PYH2_k127_4802791_20 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.0000000000001992 77.0
PYH2_k127_4802791_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 310.0
PYH2_k127_4802791_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 294.0
PYH2_k127_4802791_5 Methyltransferase FkbM domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 286.0
PYH2_k127_4802791_6 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007403 280.0
PYH2_k127_4802791_7 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004827 254.0
PYH2_k127_4802791_8 PFAM glycosyl transferase family 9 K02849 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003603 266.0
PYH2_k127_4802791_9 lipopolysaccharide heptosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003683 239.0
PYH2_k127_4842589_0 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.149e-273 853.0
PYH2_k127_4842589_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.031e-244 782.0
PYH2_k127_4842589_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 291.0
PYH2_k127_4842589_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000001154 278.0
PYH2_k127_4842589_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001627 265.0
PYH2_k127_4842589_13 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002286 261.0
PYH2_k127_4842589_14 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000008707 229.0
PYH2_k127_4842589_15 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000002337 205.0
PYH2_k127_4842589_16 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000001831 184.0
PYH2_k127_4842589_17 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000006978 165.0
PYH2_k127_4842589_18 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000459 170.0
PYH2_k127_4842589_19 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000004686 167.0
PYH2_k127_4842589_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 595.0
PYH2_k127_4842589_20 AI-2E family transporter - - - 0.000000000000000000000000000000000000002589 160.0
PYH2_k127_4842589_21 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000004438 137.0
PYH2_k127_4842589_22 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000005222 137.0
PYH2_k127_4842589_23 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000007401 133.0
PYH2_k127_4842589_24 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000002312 119.0
PYH2_k127_4842589_25 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000005583 115.0
PYH2_k127_4842589_26 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000001064 114.0
PYH2_k127_4842589_27 PFAM S23 ribosomal protein - - - 0.00000000000000000001424 104.0
PYH2_k127_4842589_28 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000003428 91.0
PYH2_k127_4842589_29 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000009201 78.0
PYH2_k127_4842589_3 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052,K07246 - 1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 558.0
PYH2_k127_4842589_30 Helix-turn-helix domain - - - 0.0000000000001579 79.0
PYH2_k127_4842589_31 Chain length determinant protein K16692 - - 0.00000007907 61.0
PYH2_k127_4842589_4 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 511.0
PYH2_k127_4842589_5 AAA ATPase, central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 472.0
PYH2_k127_4842589_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 432.0
PYH2_k127_4842589_7 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 376.0
PYH2_k127_4842589_8 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 357.0
PYH2_k127_4842589_9 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 332.0
PYH2_k127_489298_0 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 534.0
PYH2_k127_489298_1 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000005909 205.0
PYH2_k127_489298_2 Belongs to the P(II) protein family K04752 - - 0.00000000000000000000000000000000000004228 145.0
PYH2_k127_4893458_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.086e-245 768.0
PYH2_k127_4893458_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 4.073e-236 741.0
PYH2_k127_4893458_2 Biotin carboxylase C-terminal domain K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 547.0
PYH2_k127_4893458_3 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000001144 145.0
PYH2_k127_4893458_4 Biotin-requiring enzyme - - - 0.000000000000000000000000004215 117.0
PYH2_k127_4893458_5 COG COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00180 - 1.2.7.8 0.0000000000000000008304 92.0
PYH2_k127_4947678_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001782 286.0
PYH2_k127_4947678_1 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000003343 135.0
PYH2_k127_4947678_2 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000006546 143.0
PYH2_k127_4947678_3 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000007299 137.0
PYH2_k127_4947678_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000001082 129.0
PYH2_k127_4947678_5 Belongs to the UPF0434 family K09791 - - 0.000000000000009555 78.0
PYH2_k127_5025311_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1205.0
PYH2_k127_5025311_1 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 415.0
PYH2_k127_5025311_2 - - - - 0.000000000000000000000000000000000000000000000000000000000003209 214.0
PYH2_k127_509381_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 538.0
PYH2_k127_509381_1 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 542.0
PYH2_k127_509381_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 405.0
PYH2_k127_509381_3 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
PYH2_k127_509381_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000003128 210.0
PYH2_k127_509381_5 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000004601 213.0
PYH2_k127_509381_6 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000001424 68.0
PYH2_k127_509381_7 Essential cell division protein K03589 - - 0.00000000002394 75.0
PYH2_k127_5107609_0 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 471.0
PYH2_k127_5107609_1 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
PYH2_k127_5107609_2 histidine kinase, HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000001623 256.0
PYH2_k127_5107609_3 Pfam:N_methyl_2 K02650 - - 0.000000002892 63.0
PYH2_k127_5107609_4 Prokaryotic N-terminal methylation motif - - - 0.0000003045 59.0
PYH2_k127_5107609_5 Glycosyl Hydrolase Family 88 K18581 - 3.2.1.180 0.0000003975 53.0
PYH2_k127_5147419_0 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 391.0
PYH2_k127_5147419_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 286.0
PYH2_k127_5147419_2 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002273 258.0
PYH2_k127_5147419_3 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000287 185.0
PYH2_k127_5147419_4 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003328 176.0
PYH2_k127_5147419_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000006691 65.0
PYH2_k127_521218_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 601.0
PYH2_k127_521218_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001291 284.0
PYH2_k127_521218_2 Roadblock/LC7 domain - - - 0.0000007732 61.0
PYH2_k127_5260204_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 6.589e-249 781.0
PYH2_k127_5260204_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.099e-236 738.0
PYH2_k127_5260204_10 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000004488 117.0
PYH2_k127_5260204_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000002672 107.0
PYH2_k127_5260204_12 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000419 68.0
PYH2_k127_5260204_13 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000002829 63.0
PYH2_k127_5260204_14 nucleic acid-binding protein contains PIN domain - - - 0.000002679 51.0
PYH2_k127_5260204_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.746e-231 723.0
PYH2_k127_5260204_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.121e-217 704.0
PYH2_k127_5260204_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
PYH2_k127_5260204_5 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000134 261.0
PYH2_k127_5260204_6 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000002179 143.0
PYH2_k127_5260204_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000007607 135.0
PYH2_k127_5260204_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000001377 130.0
PYH2_k127_5260204_9 PIN domain K07063 - - 0.0000000000000000000000000000002232 128.0
PYH2_k127_536979_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 4.26e-242 761.0
PYH2_k127_536979_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000148 126.0
PYH2_k127_5445646_0 methyltransferase - - - 8.912e-211 664.0
PYH2_k127_5445646_1 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.878e-210 680.0
PYH2_k127_5445646_10 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 404.0
PYH2_k127_5445646_11 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 398.0
PYH2_k127_5445646_12 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 398.0
PYH2_k127_5445646_13 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 377.0
PYH2_k127_5445646_14 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007523 267.0
PYH2_k127_5445646_15 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001042 261.0
PYH2_k127_5445646_16 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
PYH2_k127_5445646_17 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000004487 258.0
PYH2_k127_5445646_18 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001271 250.0
PYH2_k127_5445646_19 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000004087 243.0
PYH2_k127_5445646_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 601.0
PYH2_k127_5445646_20 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008599 243.0
PYH2_k127_5445646_21 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000002627 233.0
PYH2_k127_5445646_22 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000002359 226.0
PYH2_k127_5445646_23 Curli production assembly transport component CsgG K04087 - - 0.000000000000000000000000000000000000000000000000000000308 207.0
PYH2_k127_5445646_24 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000003911 200.0
PYH2_k127_5445646_25 - - - - 0.0000000000000000000000000000000000000000000002252 178.0
PYH2_k127_5445646_26 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000004641 164.0
PYH2_k127_5445646_27 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000003792 158.0
PYH2_k127_5445646_28 ABC transporter K01996 - - 0.0000000000000000000000000000000000000005002 150.0
PYH2_k127_5445646_29 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000001406 151.0
PYH2_k127_5445646_3 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 590.0
PYH2_k127_5445646_30 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000001373 139.0
PYH2_k127_5445646_31 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000106 136.0
PYH2_k127_5445646_32 lysyltransferase activity K07027 - - 0.00000000000000000000000000000001957 141.0
PYH2_k127_5445646_33 Cytochrome b/b6/petB K03620 - - 0.00000000000000000000000000003634 124.0
PYH2_k127_5445646_34 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000006014 124.0
PYH2_k127_5445646_35 Histidine kinase - - - 0.000000000000000000002128 103.0
PYH2_k127_5445646_36 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000001441 106.0
PYH2_k127_5445646_37 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000007135 93.0
PYH2_k127_5445646_38 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000001237 81.0
PYH2_k127_5445646_39 HD domain - - - 0.0000000000000001583 84.0
PYH2_k127_5445646_4 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 539.0
PYH2_k127_5445646_40 FHA Domain - - - 0.000000000000001543 89.0
PYH2_k127_5445646_41 metal-dependent phosphoesterases (PHP family) - - - 0.000000000003094 75.0
PYH2_k127_5445646_42 Sensor diguanylate cyclase, GAF domain-containing - - - 0.00000000003314 76.0
PYH2_k127_5445646_43 VanZ like family - - - 0.0000006197 60.0
PYH2_k127_5445646_44 Mitochondrial domain of unknown function (DUF1713) - - - 0.00003666 47.0
PYH2_k127_5445646_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 521.0
PYH2_k127_5445646_6 Aldehyde dehydrogenase family K00128,K00131 - 1.2.1.3,1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 445.0
PYH2_k127_5445646_7 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 441.0
PYH2_k127_5445646_8 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 435.0
PYH2_k127_5445646_9 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 439.0
PYH2_k127_559359_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.38e-311 971.0
PYH2_k127_559359_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 610.0
PYH2_k127_559359_10 Resolvase, N terminal domain - - - 0.00006785 48.0
PYH2_k127_559359_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 295.0
PYH2_k127_559359_3 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000004268 255.0
PYH2_k127_559359_4 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
PYH2_k127_559359_5 Protein of unknown function (DUF2628) - - - 0.00000000000000000000000000046 121.0
PYH2_k127_559359_6 Protein of unknown function (DUF2628) - - - 0.0000000000000000000009136 102.0
PYH2_k127_559359_9 anaerobic respiration - - - 0.000005504 54.0
PYH2_k127_5616422_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.071e-228 712.0
PYH2_k127_5616422_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 442.0
PYH2_k127_5616422_2 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000001415 119.0
PYH2_k127_5616422_3 PFAM Outer membrane efflux protein - - - 0.000000008372 63.0
PYH2_k127_5651577_0 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001438 207.0
PYH2_k127_5651577_1 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000006011 199.0
PYH2_k127_5651577_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000001693 190.0
PYH2_k127_5651577_3 Capsule assembly protein Wzi - - - 0.00000000000000000000000000000000000007205 160.0
PYH2_k127_5651577_4 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.00000000000000000000000000000000003254 148.0
PYH2_k127_5651577_5 Belongs to the carbohydrate kinase PfkB family K21056 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.212 0.0000000000000000000000000001256 124.0
PYH2_k127_5651577_6 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.000000000000000001054 86.0
PYH2_k127_5651577_7 - - - - 0.0003146 50.0
PYH2_k127_5677041_0 Elongation factor Tu domain 2 K02355 - - 6.92e-223 711.0
PYH2_k127_5684229_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 3.569e-196 618.0
PYH2_k127_5684229_1 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 378.0
PYH2_k127_5684229_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004909 289.0
PYH2_k127_5729651_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 5.892e-306 957.0
PYH2_k127_5729651_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.362e-300 942.0
PYH2_k127_5729651_10 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000001192 239.0
PYH2_k127_5729651_11 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000006939 200.0
PYH2_k127_5729651_12 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000003886 123.0
PYH2_k127_5729651_13 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000003326 109.0
PYH2_k127_5729651_14 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000113 109.0
PYH2_k127_5729651_15 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000001097 85.0
PYH2_k127_5729651_16 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000005781 74.0
PYH2_k127_5729651_17 V-type ATP synthase subunit I K02123 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006873,GO:0006885,GO:0007035,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019725,GO:0019829,GO:0019899,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030003,GO:0030004,GO:0030641,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042592,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044769,GO:0045851,GO:0046034,GO:0046390,GO:0046483,GO:0046961,GO:0048878,GO:0050801,GO:0051117,GO:0051179,GO:0051234,GO:0051452,GO:0051453,GO:0055067,GO:0055080,GO:0055082,GO:0055085,GO:0055086,GO:0065007,GO:0065008,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000004417 62.0
PYH2_k127_5729651_18 TIGRFAM tol-pal system protein YbgF - - - 0.00005962 56.0
PYH2_k127_5729651_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.759e-215 687.0
PYH2_k127_5729651_3 SMART Nucleotide binding protein PINc K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 468.0
PYH2_k127_5729651_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 468.0
PYH2_k127_5729651_5 PFAM Integrase, catalytic core - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 430.0
PYH2_k127_5729651_6 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 348.0
PYH2_k127_5729651_7 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 324.0
PYH2_k127_5729651_8 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 298.0
PYH2_k127_5729651_9 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000004036 271.0
PYH2_k127_5781392_0 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.0 1239.0
PYH2_k127_5781392_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.408e-199 634.0
PYH2_k127_5781392_2 cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 348.0
PYH2_k127_5781392_3 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 360.0
PYH2_k127_5781392_5 - - - - 0.000000000000000000000000000000001237 130.0
PYH2_k127_5781392_6 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000007127 98.0
PYH2_k127_5781392_7 Diguanylate cyclase - - - 0.0000000000000112 86.0
PYH2_k127_5781392_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0002031 44.0
PYH2_k127_5858196_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 546.0
PYH2_k127_5858196_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 527.0
PYH2_k127_5858196_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 390.0
PYH2_k127_5858196_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 325.0
PYH2_k127_5858196_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 307.0
PYH2_k127_5858196_5 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 287.0
PYH2_k127_5858196_6 Transposase IS200 like - - - 0.0000000000000000000000000000026 126.0
PYH2_k127_5858196_7 - - - - 0.000000000000000000000001212 106.0
PYH2_k127_5922839_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 2.221e-240 757.0
PYH2_k127_5922839_1 TIGRFAM formate dehydrogenase, alpha subunit K00123,K00336,K05299 - 1.17.1.10,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 626.0
PYH2_k127_5922839_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
PYH2_k127_5922839_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001137 167.0
PYH2_k127_5922839_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000002182 142.0
PYH2_k127_5922839_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000007881 126.0
PYH2_k127_5922839_6 Tetratricopeptide repeat - - - 0.000000000000002014 91.0
PYH2_k127_5922839_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000168 47.0
PYH2_k127_5925571_0 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000007234 195.0
PYH2_k127_5925571_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000004662 175.0
PYH2_k127_5925571_2 - - - - 0.0000000000000000000000000000000000000000001052 177.0
PYH2_k127_5925571_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000003123 145.0
PYH2_k127_5925571_4 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000004371 95.0
PYH2_k127_5925571_5 Protein of unknown function (DUF1622) - - - 0.00000000000000001139 87.0
PYH2_k127_5925571_6 - - - - 0.0000000002611 69.0
PYH2_k127_5925571_7 - - - - 0.00000004833 63.0
PYH2_k127_5979341_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 506.0
PYH2_k127_5979341_1 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 401.0
PYH2_k127_5979341_10 Protein of unknown function (DUF2953) - - - 0.00000000000000000000001755 107.0
PYH2_k127_5979341_11 Domain of unknown function (DUF305) - - - 0.00000000000000000002514 99.0
PYH2_k127_5979341_2 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001764 257.0
PYH2_k127_5979341_3 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001056 235.0
PYH2_k127_5979341_4 LemA family K03744 - - 0.000000000000000000000000000000000000000000000002644 179.0
PYH2_k127_5979341_5 MgtC family K07507 - - 0.000000000000000000000000000000000000000000704 160.0
PYH2_k127_5979341_6 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000004194 144.0
PYH2_k127_5979341_7 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000000000000000003683 135.0
PYH2_k127_5979341_8 PFAM Membrane protein of K08972 - - 0.00000000000000000000000000000002542 130.0
PYH2_k127_5979341_9 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000021 137.0
PYH2_k127_60255_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 348.0
PYH2_k127_60255_1 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 334.0
PYH2_k127_60255_2 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
PYH2_k127_60255_3 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000001651 228.0
PYH2_k127_6027983_0 Penicillin-binding protein 1A K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004695 445.0
PYH2_k127_6027983_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 324.0
PYH2_k127_6027983_2 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003095 250.0
PYH2_k127_6027983_3 HD domain K07814 - - 0.00000000000000000000000000000000000002242 166.0
PYH2_k127_6027983_4 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.0000000000000000000000000000000007966 148.0
PYH2_k127_6295893_0 Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing - - - 5.347e-219 721.0
PYH2_k127_6295893_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 604.0
PYH2_k127_6295893_10 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 357.0
PYH2_k127_6295893_11 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001041 293.0
PYH2_k127_6295893_12 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000003052 271.0
PYH2_k127_6295893_13 xylanase chitin deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000006481 240.0
PYH2_k127_6295893_14 Helix-turn-helix transcriptional regulator PuuR, cupin domain-containing - - - 0.00000000000000000000000000000000000000000000000000005373 193.0
PYH2_k127_6295893_15 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000000000000003646 202.0
PYH2_k127_6295893_16 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.000000000000000000000000000000000000000000000000002344 188.0
PYH2_k127_6295893_17 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000007569 186.0
PYH2_k127_6295893_18 acetyltransferase K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000006698 186.0
PYH2_k127_6295893_19 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000002845 198.0
PYH2_k127_6295893_2 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 612.0
PYH2_k127_6295893_20 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000001314 180.0
PYH2_k127_6295893_21 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000002198 170.0
PYH2_k127_6295893_22 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000001755 172.0
PYH2_k127_6295893_23 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000002516 151.0
PYH2_k127_6295893_24 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000001191 149.0
PYH2_k127_6295893_25 - K16923 - - 0.000000000000000000000000000001646 141.0
PYH2_k127_6295893_26 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000009832 110.0
PYH2_k127_6295893_27 PFAM FMN-binding domain K21559 - - 0.000000000000000000007625 106.0
PYH2_k127_6295893_29 (FHA) domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000001797 69.0
PYH2_k127_6295893_3 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes K08321,K11645 - 2.3.1.245,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 434.0
PYH2_k127_6295893_4 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 412.0
PYH2_k127_6295893_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 414.0
PYH2_k127_6295893_6 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
PYH2_k127_6295893_7 PRTRC system protein D K18640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
PYH2_k127_6295893_8 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 339.0
PYH2_k127_6295893_9 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 347.0
PYH2_k127_6330398_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1566.0
PYH2_k127_6330398_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 439.0
PYH2_k127_6330398_10 translation initiation factor activity K03646 - - 0.000000000000002323 89.0
PYH2_k127_6330398_11 Membrane - - - 0.000000000000002676 83.0
PYH2_k127_6330398_12 - - - - 0.00000007996 65.0
PYH2_k127_6330398_13 Tetratricopeptide repeat - - - 0.0000009822 61.0
PYH2_k127_6330398_14 - - - - 0.000001995 50.0
PYH2_k127_6330398_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 365.0
PYH2_k127_6330398_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 328.0
PYH2_k127_6330398_4 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 312.0
PYH2_k127_6330398_5 Psort location Extracellular, score - - - 0.0000000000000000000000000000000000000000000000000000000000000001188 231.0
PYH2_k127_6330398_6 NosL - - - 0.00000000000000000000000000000000000000000000000002279 184.0
PYH2_k127_6330398_7 PFAM NosL family protein - - - 0.0000000000000000000000000000000000001736 150.0
PYH2_k127_6330398_8 Thioredoxin-like - - - 0.000000000000000000000003103 109.0
PYH2_k127_6330398_9 - - - - 0.00000000000000000000003533 102.0
PYH2_k127_6459863_0 SMART Elongator protein 3 MiaB NifB - - - 2.263e-201 662.0
PYH2_k127_6459863_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 574.0
PYH2_k127_6459863_10 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000001387 221.0
PYH2_k127_6459863_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000002297 207.0
PYH2_k127_6459863_12 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0070930,GO:0071704,GO:0097159,GO:1901363,GO:1901564 - 0.000000000000000000000000000000000000000000000007075 176.0
PYH2_k127_6459863_13 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000873 173.0
PYH2_k127_6459863_14 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000004881 162.0
PYH2_k127_6459863_15 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000002423 149.0
PYH2_k127_6459863_16 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000001803 133.0
PYH2_k127_6459863_17 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000002394 130.0
PYH2_k127_6459863_18 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000003848 117.0
PYH2_k127_6459863_19 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000001572 109.0
PYH2_k127_6459863_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002371 572.0
PYH2_k127_6459863_20 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000005288 111.0
PYH2_k127_6459863_21 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000007167 92.0
PYH2_k127_6459863_22 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000004197 84.0
PYH2_k127_6459863_23 FmdB family - - - 0.00000000000001109 77.0
PYH2_k127_6459863_24 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.000004675 49.0
PYH2_k127_6459863_3 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 497.0
PYH2_k127_6459863_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 382.0
PYH2_k127_6459863_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 382.0
PYH2_k127_6459863_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 376.0
PYH2_k127_6459863_7 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 317.0
PYH2_k127_6459863_8 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005356 274.0
PYH2_k127_6459863_9 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
PYH2_k127_6501520_0 nitric oxide dioxygenase activity - - - 0.00000000000000000000000002542 123.0
PYH2_k127_6501520_1 Nucleotidyltransferase - - - 0.0000000000000000006661 96.0
PYH2_k127_6501520_3 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.00008558 47.0
PYH2_k127_6548007_0 tRNA synthetases class I (K) K01870 - 6.1.1.5 6.053e-249 784.0
PYH2_k127_6548007_1 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 1.396e-236 739.0
PYH2_k127_6548007_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000028 243.0
PYH2_k127_6548007_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000004505 216.0
PYH2_k127_6548007_4 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000000000000000000000000000001188 186.0
PYH2_k127_6548007_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000001874 144.0
PYH2_k127_6548007_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000006695 138.0
PYH2_k127_6556566_0 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 488.0
PYH2_k127_6556566_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 461.0
PYH2_k127_6556566_10 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000084 258.0
PYH2_k127_6556566_11 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
PYH2_k127_6556566_12 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000001134 241.0
PYH2_k127_6556566_13 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000006051 236.0
PYH2_k127_6556566_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000002838 232.0
PYH2_k127_6556566_15 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000001688 238.0
PYH2_k127_6556566_16 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000004785 216.0
PYH2_k127_6556566_17 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000003716 143.0
PYH2_k127_6556566_18 Yqey-like protein K09117 - - 0.000000000000000000000000000000000003613 142.0
PYH2_k127_6556566_19 Binds the 23S rRNA K02909 - - 0.0000000000000000000000005365 105.0
PYH2_k127_6556566_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 438.0
PYH2_k127_6556566_20 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001188 88.0
PYH2_k127_6556566_3 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 440.0
PYH2_k127_6556566_4 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
PYH2_k127_6556566_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 392.0
PYH2_k127_6556566_6 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 362.0
PYH2_k127_6556566_7 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 318.0
PYH2_k127_6556566_8 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 322.0
PYH2_k127_6556566_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005508 281.0
PYH2_k127_6599485_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 458.0
PYH2_k127_6599485_1 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 448.0
PYH2_k127_6599485_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 304.0
PYH2_k127_6599485_3 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001751 278.0
PYH2_k127_6599485_4 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000006785 140.0
PYH2_k127_6599485_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000005272 110.0
PYH2_k127_6599485_6 PFAM FecR protein - - - 0.000000000000000000000001096 119.0
PYH2_k127_6599485_7 Bacterial dnaA protein helix-turn-helix K07491 - - 0.00000000000000000001271 97.0
PYH2_k127_6599485_8 Uroporphyrinogen-III synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000002285 57.0
PYH2_k127_6599485_9 - - - - 0.0000405 53.0
PYH2_k127_6602144_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1230.0
PYH2_k127_6602144_1 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 5.215e-205 652.0
PYH2_k127_6602144_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088,K00364 GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 1.1.1.205,1.7.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 591.0
PYH2_k127_6602144_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 321.0
PYH2_k127_6602144_4 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000002744 211.0
PYH2_k127_6602144_5 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000004615 191.0
PYH2_k127_6602144_6 - - - - 0.0000000001151 65.0
PYH2_k127_6670584_0 UvrD/REP helicase N-terminal domain - - - 5.506e-229 747.0
PYH2_k127_6670584_1 exonuclease activity K16899 - 3.6.4.12 3.776e-205 675.0
PYH2_k127_6670584_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 356.0
PYH2_k127_6670584_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.0000000000000000000000000000000000000000000000000000000000000001626 237.0
PYH2_k127_6710763_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 316.0
PYH2_k127_6710763_1 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000005731 207.0
PYH2_k127_6710763_2 - - - - 0.00000000000000000000000000001185 123.0
PYH2_k127_6710763_3 - - - - 0.000000003721 57.0
PYH2_k127_6765739_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000006746 226.0
PYH2_k127_6765739_1 ABC transporter substrate binding protein K01989 - - 0.000000000003 77.0
PYH2_k127_6793039_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 357.0
PYH2_k127_6793039_1 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000000000000002107 216.0
PYH2_k127_6793039_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000002188 199.0
PYH2_k127_6793039_3 - - - - 0.0000000000000000000000000000000000000000000000001186 184.0
PYH2_k127_6793039_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000003157 188.0
PYH2_k127_6817011_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 604.0
PYH2_k127_6817011_1 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001733 235.0
PYH2_k127_6817011_2 ATP cone domain K07738 - - 0.000000000000000000000000000000000000000000000000000000000000003218 224.0
PYH2_k127_6817011_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000001709 189.0
PYH2_k127_6817011_4 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000003564 180.0
PYH2_k127_6817011_5 Part of a membrane complex involved in electron transport K03615 - - 0.000000003617 63.0
PYH2_k127_6858381_0 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
PYH2_k127_6858381_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000001426 162.0
PYH2_k127_6858381_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000004039 109.0
PYH2_k127_6858381_3 histidine kinase A domain protein - - - 0.0000000003647 70.0
PYH2_k127_6860434_0 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 288.0
PYH2_k127_6860434_1 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004479 256.0
PYH2_k127_6860434_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000004638 205.0
PYH2_k127_6860434_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000006324 160.0
PYH2_k127_6860434_4 PAP2 superfamily - - - 0.000001104 61.0
PYH2_k127_6860434_5 Tetratricopeptide repeat - - - 0.000003622 57.0
PYH2_k127_6860434_6 - - - - 0.0002915 49.0
PYH2_k127_6867020_0 Belongs to the CarB family K01955 - 6.3.5.5 1.001e-227 715.0
PYH2_k127_6867020_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 548.0
PYH2_k127_6867020_2 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 358.0
PYH2_k127_6867020_3 anaerobic electron transport chain - GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016491,GO:0019645,GO:0022900,GO:0022904,GO:0044237,GO:0045333,GO:0055114 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008043 377.0
PYH2_k127_6867020_4 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004181 294.0
PYH2_k127_6867020_5 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000006276 197.0
PYH2_k127_6867020_6 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000003144 194.0
PYH2_k127_6867020_7 Oxidoreductase NAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000000009937 177.0
PYH2_k127_6867020_8 cheY-homologous receiver domain - - - 0.0000000000000000000000003768 109.0
PYH2_k127_6867020_9 Transglutaminase/protease-like homologues - - - 0.0000000000000000000008584 110.0
PYH2_k127_6873201_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008599 283.0
PYH2_k127_6873201_1 PEP-CTERM motif - - - 0.000000000000000000000000000000000002381 145.0
PYH2_k127_6878707_0 alginic acid biosynthetic process K20276 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000242 278.0
PYH2_k127_6878707_1 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000001346 196.0
PYH2_k127_6878707_2 oligosaccharyl transferase activity - - - 0.00000000000000000000000006282 124.0
PYH2_k127_6878707_3 alginic acid biosynthetic process - - - 0.0000000000000000001836 104.0
PYH2_k127_6878707_4 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000004552 81.0
PYH2_k127_6878707_5 OmpA-like transmembrane domain - - - 0.0000001251 60.0
PYH2_k127_6890605_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 537.0
PYH2_k127_6890605_1 Protein of unknown function (DUF2867) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009058 492.0
PYH2_k127_6890605_10 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 272.0
PYH2_k127_6890605_11 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
PYH2_k127_6890605_12 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000002049 222.0
PYH2_k127_6890605_13 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000005106 161.0
PYH2_k127_6890605_14 SOUL heme-binding protein - - - 0.00000000000000000000000000000000000000000122 164.0
PYH2_k127_6890605_15 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000002913 156.0
PYH2_k127_6890605_16 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000006686 133.0
PYH2_k127_6890605_17 PFAM Ankyrin - - - 0.0000000000000000000000000000009061 138.0
PYH2_k127_6890605_18 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000004912 100.0
PYH2_k127_6890605_19 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000021 93.0
PYH2_k127_6890605_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 476.0
PYH2_k127_6890605_20 transcriptional regulator K07726 - - 0.000000000000000002162 100.0
PYH2_k127_6890605_21 - K07341 - - 0.000000000000000002882 90.0
PYH2_k127_6890605_22 Predicted membrane protein (DUF2232) - - - 0.0000000002432 72.0
PYH2_k127_6890605_3 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 442.0
PYH2_k127_6890605_4 transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009329 406.0
PYH2_k127_6890605_5 nitric oxide dioxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006947 352.0
PYH2_k127_6890605_6 COG1127 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 307.0
PYH2_k127_6890605_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004847 314.0
PYH2_k127_6890605_8 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005072 290.0
PYH2_k127_6890605_9 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006562 281.0
PYH2_k127_6953387_0 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 354.0
PYH2_k127_6953387_1 lysyltransferase activity - - - 0.0000000000000000000000000004339 126.0
PYH2_k127_6974926_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.775e-203 638.0
PYH2_k127_6974926_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 531.0
PYH2_k127_6974926_10 system, mannose fructose sorbose family IID component K02795,K02796,K10986 - - 0.0000000000000000000001236 111.0
PYH2_k127_6974926_11 PTS HPr component phosphorylation site K11189 - - 0.0000000000003163 83.0
PYH2_k127_6974926_12 TIGRFAM lipopolysaccharide transport periplasmic protein LptA K09774 - - 0.000000004342 63.0
PYH2_k127_6974926_13 PTS system sorbose-specific iic component K02795 - - 0.000002024 59.0
PYH2_k127_6974926_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 437.0
PYH2_k127_6974926_3 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 299.0
PYH2_k127_6974926_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005615 259.0
PYH2_k127_6974926_5 - - - - 0.00000000000000000000000000000000000000000000000002162 190.0
PYH2_k127_6974926_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000002083 173.0
PYH2_k127_6974926_7 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000003042 153.0
PYH2_k127_6974926_8 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000002217 127.0
PYH2_k127_6974926_9 PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000001692 116.0
PYH2_k127_7147763_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.355e-279 871.0
PYH2_k127_7147763_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 8.709e-213 692.0
PYH2_k127_7147763_10 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K00760,K04075,K15780 - 2.4.2.8,6.3.4.19 0.00000000000000000000000000000000001764 151.0
PYH2_k127_7147763_11 PFAM CBS domain - - - 0.00000000000000000000000000000000001977 148.0
PYH2_k127_7147763_12 PFAM YbbR family protein - - - 0.000000000000000000000000000000002463 137.0
PYH2_k127_7147763_13 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000005474 118.0
PYH2_k127_7147763_14 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000003651 123.0
PYH2_k127_7147763_15 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000172 104.0
PYH2_k127_7147763_16 TilS substrate binding domain K04075 - 6.3.4.19 0.00000000000000005287 94.0
PYH2_k127_7147763_17 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00002338 53.0
PYH2_k127_7147763_2 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 564.0
PYH2_k127_7147763_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 464.0
PYH2_k127_7147763_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 429.0
PYH2_k127_7147763_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 402.0
PYH2_k127_7147763_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 327.0
PYH2_k127_7147763_7 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 302.0
PYH2_k127_7147763_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000004514 250.0
PYH2_k127_7147763_9 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000002517 168.0
PYH2_k127_7198248_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 471.0
PYH2_k127_7198248_1 PilZ domain - - - 0.0000000000000000000000000000000000002132 149.0
PYH2_k127_7198248_2 Radical_SAM C-terminal domain K07139 - - 0.00000000000000000000000000000000008243 139.0
PYH2_k127_7198248_3 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000005608 80.0
PYH2_k127_7221401_0 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 1.979e-210 672.0
PYH2_k127_7221401_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 561.0
PYH2_k127_7221401_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 392.0
PYH2_k127_7221401_3 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007559 351.0
PYH2_k127_7221401_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000004621 118.0
PYH2_k127_7358083_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 9.866e-224 720.0
PYH2_k127_7358083_1 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 428.0
PYH2_k127_7358083_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 356.0
PYH2_k127_7358083_3 glutamine amidotransferase K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000001552 182.0
PYH2_k127_7358083_4 Peptidase family M23 - - - 0.000000000000000000000000000000000000000001279 168.0
PYH2_k127_7358083_5 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000005756 98.0
PYH2_k127_7358083_6 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000004729 98.0
PYH2_k127_7358083_7 - - - - 0.000000000000002482 79.0
PYH2_k127_7358083_8 Cold shock K03704 - - 0.0000000000002777 70.0
PYH2_k127_7391448_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 446.0
PYH2_k127_7391448_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 371.0
PYH2_k127_7391448_2 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000002144 219.0
PYH2_k127_7391448_3 PFAM Pyruvate ketoisovalerate oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000001119 197.0
PYH2_k127_7391448_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000002734 199.0
PYH2_k127_7391448_5 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000001635 85.0
PYH2_k127_7399301_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 8.76e-243 769.0
PYH2_k127_7399301_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007352 563.0
PYH2_k127_7399301_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 536.0
PYH2_k127_7399301_3 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 369.0
PYH2_k127_7399301_4 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002271 248.0
PYH2_k127_7399301_5 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000005274 216.0
PYH2_k127_7399301_6 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000001642 195.0
PYH2_k127_7399301_7 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001891 127.0
PYH2_k127_7399301_8 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000001993 95.0
PYH2_k127_7399301_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000004446 97.0
PYH2_k127_7423297_0 PFAM ferredoxin-dependent glutamate synthase - - - 9.159e-286 883.0
PYH2_k127_7423297_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 7.394e-239 753.0
PYH2_k127_7423297_10 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000002728 149.0
PYH2_k127_7423297_11 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000007691 149.0
PYH2_k127_7423297_12 SMART regulatory protein ArsR - - - 0.00000000000000000000000000000832 122.0
PYH2_k127_7423297_13 oligosaccharyl transferase activity - - - 0.000000000000000000000000009863 126.0
PYH2_k127_7423297_14 - - - - 0.0000000000000000000000003638 121.0
PYH2_k127_7423297_15 Thioredoxin domain - - - 0.000000000000000000000004033 103.0
PYH2_k127_7423297_17 Protein kinase domain - - - 0.000000004317 61.0
PYH2_k127_7423297_2 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 559.0
PYH2_k127_7423297_3 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008731 477.0
PYH2_k127_7423297_4 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006075 365.0
PYH2_k127_7423297_5 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 346.0
PYH2_k127_7423297_6 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 328.0
PYH2_k127_7423297_7 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005033 284.0
PYH2_k127_7423297_8 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000001213 245.0
PYH2_k127_7423297_9 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000007188 203.0
PYH2_k127_7458924_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 2.224e-281 890.0
PYH2_k127_7458924_1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 1.083e-218 700.0
PYH2_k127_7458924_2 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 486.0
PYH2_k127_7458924_3 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 319.0
PYH2_k127_7458924_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 311.0
PYH2_k127_7458924_5 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001351 279.0
PYH2_k127_7458924_6 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003501 244.0
PYH2_k127_7458924_7 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000008807 225.0
PYH2_k127_7530079_0 TonB-dependent Receptor Plug K16092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001355 270.0
PYH2_k127_7530079_1 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000009955 201.0
PYH2_k127_7530079_2 RF-1 domain - - - 0.0000000004351 64.0
PYH2_k127_7532105_0 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000008187 188.0
PYH2_k127_7532105_1 Domain of unknown function (DUF4349) - - - 0.0000000000000000000007606 107.0
PYH2_k127_7532105_2 PFAM transposase mutator type - - - 0.0000000001528 64.0
PYH2_k127_7532105_3 - - - - 0.0000000009094 71.0
PYH2_k127_7532105_4 - - - - 0.00000001068 66.0
PYH2_k127_7543536_0 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 401.0
PYH2_k127_7543536_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 395.0
PYH2_k127_7543536_2 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000003256 228.0
PYH2_k127_7543536_3 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000009879 203.0
PYH2_k127_7543536_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000002453 190.0
PYH2_k127_7543536_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000006556 174.0
PYH2_k127_7543536_6 CBS domain K00974 - 2.7.7.72 0.00000000000000000003638 97.0
PYH2_k127_7543536_7 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00437,K00533,K05922,K06281 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.12.2.1,1.12.5.1,1.12.7.2,1.12.99.6 0.00000000005582 63.0
PYH2_k127_7555832_0 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000002471 198.0
PYH2_k127_7555832_1 Cytochrome P460 - - - 0.000000000000000000000000000001244 130.0
PYH2_k127_7555832_2 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000002094 127.0
PYH2_k127_7555832_3 Zn-dependent protease - - - 0.00007396 53.0
PYH2_k127_7555832_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001785 51.0
PYH2_k127_7556253_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1029.0
PYH2_k127_7556253_1 RNA polymerase I subunit A N-terminus K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 286.0
PYH2_k127_7556253_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000001143 220.0
PYH2_k127_7556253_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000001461 223.0
PYH2_k127_7556253_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001559 79.0
PYH2_k127_7556261_0 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 595.0
PYH2_k127_7556261_1 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008026 456.0
PYH2_k127_7556261_2 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007687 281.0
PYH2_k127_7556261_3 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000001814 181.0
PYH2_k127_7556261_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000006696 78.0
PYH2_k127_7623800_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.083e-246 777.0
PYH2_k127_7623800_1 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 372.0
PYH2_k127_7623800_2 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 331.0
PYH2_k127_7623800_3 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 300.0
PYH2_k127_7623800_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000005106 239.0
PYH2_k127_7623800_5 - - - - 0.0000000000000000000000000000000000000001008 174.0
PYH2_k127_7623800_6 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.0000000000000000000000000000000000000002372 169.0
PYH2_k127_7623800_7 Sulfatase K01138 - - 0.000000000000000000000000000002652 136.0
PYH2_k127_7623800_8 Methyltransferase domain - - - 0.00000000000000000002356 100.0
PYH2_k127_7647581_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 539.0
PYH2_k127_7647581_1 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002903 288.0
PYH2_k127_7647581_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002474 272.0
PYH2_k127_7647581_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001318 246.0
PYH2_k127_7647581_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000008134 237.0
PYH2_k127_7647581_5 HEAT repeat - - - 0.0000000000000000000000000000000000000001239 162.0
PYH2_k127_7647581_7 ResB-like family - - - 0.000000000005812 73.0
PYH2_k127_7686219_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 384.0
PYH2_k127_7686219_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000003323 186.0
PYH2_k127_7686219_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.00000000000000000000000000000000000165 148.0
PYH2_k127_7686219_3 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000002785 138.0
PYH2_k127_7686219_4 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.0000000000000000005937 94.0
PYH2_k127_7686219_5 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0003362 49.0
PYH2_k127_7708379_0 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000001499 152.0
PYH2_k127_7708379_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.0000000000000000000000003236 122.0
PYH2_k127_7708379_2 membrane-anchored protein - - - 0.000000121 62.0
PYH2_k127_7708744_0 Aminotransferase class IV K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 444.0
PYH2_k127_7708744_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000004869 213.0
PYH2_k127_7708744_2 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000001621 147.0
PYH2_k127_7708744_3 TfoX N-terminal domain - - - 0.00000000000000004282 89.0
PYH2_k127_7708744_4 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000002272 77.0
PYH2_k127_7708744_5 repeat-containing protein - - - 0.00000002506 61.0
PYH2_k127_7724158_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.275e-202 637.0
PYH2_k127_7724158_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 397.0
PYH2_k127_7724158_10 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000002266 156.0
PYH2_k127_7724158_11 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000001248 148.0
PYH2_k127_7724158_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000001507 144.0
PYH2_k127_7724158_13 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000001572 141.0
PYH2_k127_7724158_14 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000001958 131.0
PYH2_k127_7724158_15 Ribosomal protein L22p/L17e K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000004466 126.0
PYH2_k127_7724158_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000002686 109.0
PYH2_k127_7724158_17 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005591 104.0
PYH2_k127_7724158_18 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000001785 70.0
PYH2_k127_7724158_19 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000001928 71.0
PYH2_k127_7724158_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 325.0
PYH2_k127_7724158_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 297.0
PYH2_k127_7724158_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004029 275.0
PYH2_k127_7724158_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000009625 217.0
PYH2_k127_7724158_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000004109 212.0
PYH2_k127_7724158_7 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000002551 201.0
PYH2_k127_7724158_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003738 192.0
PYH2_k127_7724158_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000007442 171.0
PYH2_k127_7760066_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003684 356.0
PYH2_k127_7760066_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005359 301.0
PYH2_k127_7760066_2 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000005845 233.0
PYH2_k127_7760066_3 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000001588 128.0
PYH2_k127_7760066_4 dUTPase K01520 - 3.6.1.23 0.0001369 51.0
PYH2_k127_7802554_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.561e-298 938.0
PYH2_k127_7802554_1 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 624.0
PYH2_k127_7802554_10 Prokaryotic N-terminal methylation motif K02457 - - 0.0000007159 60.0
PYH2_k127_7802554_11 general secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.000002505 57.0
PYH2_k127_7802554_12 Fimbrial assembly family protein K02461 - - 0.000018 56.0
PYH2_k127_7802554_13 overlaps another CDS with the same product name K02458 - - 0.0004651 51.0
PYH2_k127_7802554_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 513.0
PYH2_k127_7802554_3 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 508.0
PYH2_k127_7802554_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 381.0
PYH2_k127_7802554_5 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 306.0
PYH2_k127_7802554_6 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000247 194.0
PYH2_k127_7802554_7 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000000000000000000000000000004353 178.0
PYH2_k127_7802554_8 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000000000001097 141.0
PYH2_k127_7802554_9 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000004538 82.0
PYH2_k127_7823018_0 phosphatidate phosphatase activity K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 402.0
PYH2_k127_7823018_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000007108 145.0
PYH2_k127_7823018_2 GIY-YIG catalytic domain - - - 0.00000000000000000000000000003173 121.0
PYH2_k127_7823018_4 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000001118 78.0
PYH2_k127_7823018_5 GIY-YIG catalytic domain K07461 - - 0.00000000106 62.0
PYH2_k127_7852225_0 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 503.0
PYH2_k127_7852225_1 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009523 477.0
PYH2_k127_7852225_10 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000007493 126.0
PYH2_k127_7852225_11 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000008966 114.0
PYH2_k127_7852225_12 - - - - 0.000000000000000002941 90.0
PYH2_k127_7852225_14 RDD family - - - 0.000000001403 64.0
PYH2_k127_7852225_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 424.0
PYH2_k127_7852225_3 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
PYH2_k127_7852225_4 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 321.0
PYH2_k127_7852225_5 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005099 241.0
PYH2_k127_7852225_6 - - - - 0.000000000000000000000000000000000000000000000000001537 189.0
PYH2_k127_7852225_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000001651 145.0
PYH2_k127_7852225_8 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000007015 124.0
PYH2_k127_7852225_9 SPTR CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000000000001474 116.0
PYH2_k127_7868394_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.168e-240 777.0
PYH2_k127_7868394_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 588.0
PYH2_k127_7868394_10 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 364.0
PYH2_k127_7868394_11 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 363.0
PYH2_k127_7868394_12 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002962 322.0
PYH2_k127_7868394_13 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 313.0
PYH2_k127_7868394_14 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 325.0
PYH2_k127_7868394_15 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005363 301.0
PYH2_k127_7868394_16 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 294.0
PYH2_k127_7868394_17 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 274.0
PYH2_k127_7868394_18 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000235 263.0
PYH2_k127_7868394_19 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
PYH2_k127_7868394_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 540.0
PYH2_k127_7868394_20 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000003644 246.0
PYH2_k127_7868394_21 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000000001497 152.0
PYH2_k127_7868394_22 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000003859 145.0
PYH2_k127_7868394_23 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000005038 139.0
PYH2_k127_7868394_24 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000001802 126.0
PYH2_k127_7868394_25 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000563 132.0
PYH2_k127_7868394_26 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000454 125.0
PYH2_k127_7868394_27 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000001216 85.0
PYH2_k127_7868394_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 517.0
PYH2_k127_7868394_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 488.0
PYH2_k127_7868394_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 447.0
PYH2_k127_7868394_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 380.0
PYH2_k127_7868394_7 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 387.0
PYH2_k127_7868394_8 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 371.0
PYH2_k127_7868394_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 366.0
PYH2_k127_7882672_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 521.0
PYH2_k127_7882672_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 398.0
PYH2_k127_7882672_10 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000002377 128.0
PYH2_k127_7882672_11 SMART Elongator protein 3 MiaB NifB K07139 - - 0.000000000000000000000000881 111.0
PYH2_k127_7882672_12 - - - - 0.00000000000000000000004906 102.0
PYH2_k127_7882672_13 C4-type zinc ribbon domain K07164 - - 0.000000002076 58.0
PYH2_k127_7882672_14 - - - - 0.0000001573 61.0
PYH2_k127_7882672_15 Forms part of a two-component regulatory system AfsQ1 AfsQ2 involved in secondary metabolism - - - 0.0000008848 60.0
PYH2_k127_7882672_16 LppC putative lipoprotein - - - 0.0000418 49.0
PYH2_k127_7882672_2 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 392.0
PYH2_k127_7882672_3 Radical SAM superfamily K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 359.0
PYH2_k127_7882672_4 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 342.0
PYH2_k127_7882672_5 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 291.0
PYH2_k127_7882672_6 SMART CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008659 267.0
PYH2_k127_7882672_7 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000001187 248.0
PYH2_k127_7882672_8 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000009127 240.0
PYH2_k127_7882672_9 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000004078 172.0
PYH2_k127_789202_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.571e-213 678.0
PYH2_k127_789202_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 454.0
PYH2_k127_789202_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003273 265.0
PYH2_k127_789202_11 Prephenate dehydratase K14170 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000003652 262.0
PYH2_k127_789202_12 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000002093 241.0
PYH2_k127_789202_13 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000005646 224.0
PYH2_k127_789202_14 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000011 202.0
PYH2_k127_789202_15 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000001152 213.0
PYH2_k127_789202_16 DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000004583 194.0
PYH2_k127_789202_17 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000001337 171.0
PYH2_k127_789202_18 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000006109 179.0
PYH2_k127_789202_19 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000388 152.0
PYH2_k127_789202_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 444.0
PYH2_k127_789202_20 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000004779 131.0
PYH2_k127_789202_21 regulation of translation K05788 - - 0.000000000000000000000000000009136 121.0
PYH2_k127_789202_22 oligosaccharyl transferase activity - - - 0.00000000000000000000003006 115.0
PYH2_k127_789202_23 peroxiredoxin activity - - - 0.00000000000000000000006685 113.0
PYH2_k127_789202_24 photosynthesis K02453,K02660 - - 0.00000001103 67.0
PYH2_k127_789202_25 domain protein K20276 - - 0.00000001385 66.0
PYH2_k127_789202_3 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 434.0
PYH2_k127_789202_4 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 407.0
PYH2_k127_789202_5 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 356.0
PYH2_k127_789202_6 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 355.0
PYH2_k127_789202_7 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 337.0
PYH2_k127_789202_8 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 316.0
PYH2_k127_789202_9 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 296.0
PYH2_k127_789728_0 Secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 446.0
PYH2_k127_789728_1 reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000004935 205.0
PYH2_k127_789728_2 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000001449 177.0
PYH2_k127_789728_3 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000009393 79.0
PYH2_k127_789728_4 Type II secretion system K12510 - - 0.0000000000009794 78.0
PYH2_k127_789728_6 Uncharacterized ACR, COG1430 K09005 - - 0.0000263 52.0
PYH2_k127_789728_7 Type II secretion system K12511 - - 0.0001225 55.0
PYH2_k127_789728_8 - - - - 0.0006129 51.0
PYH2_k127_7900442_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 511.0
PYH2_k127_7900442_1 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000001466 188.0
PYH2_k127_7943775_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 7.562e-262 824.0
PYH2_k127_7943775_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 607.0
PYH2_k127_7943775_10 TIGR00255 family - - - 0.0000000000000000000000000000000000000000000000007932 185.0
PYH2_k127_7943775_11 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000007665 148.0
PYH2_k127_7943775_12 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000009096 139.0
PYH2_k127_7943775_13 Tetratricopeptide repeat - - - 0.0000000000000000000000001162 119.0
PYH2_k127_7943775_14 - - - - 0.000000000000000000000002585 119.0
PYH2_k127_7943775_15 phosphorelay signal transduction system - - - 0.000000000000000000004299 110.0
PYH2_k127_7943775_16 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000004316 90.0
PYH2_k127_7943775_17 response regulator, receiver K03413 - - 0.00000000000000009307 95.0
PYH2_k127_7943775_19 sequence-specific DNA binding K15539 - - 0.00000001231 59.0
PYH2_k127_7943775_2 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 312.0
PYH2_k127_7943775_20 PFAM Chorismate mutase, type II - - - 0.0000004229 57.0
PYH2_k127_7943775_21 Tetratricopeptide repeat - - - 0.000002371 57.0
PYH2_k127_7943775_22 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00002552 51.0
PYH2_k127_7943775_23 - - - - 0.00005459 55.0
PYH2_k127_7943775_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 293.0
PYH2_k127_7943775_4 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004642 288.0
PYH2_k127_7943775_5 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004546 291.0
PYH2_k127_7943775_6 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006478 272.0
PYH2_k127_7943775_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000269 223.0
PYH2_k127_7943775_8 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000004961 218.0
PYH2_k127_7943775_9 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000007682 199.0
PYH2_k127_7962645_0 - - - - 0.00000000004744 70.0
PYH2_k127_7962645_1 lyase activity - - - 0.000000002438 70.0
PYH2_k127_7962645_2 nitrogen fixation negative regulator NifL - - - 0.00000001008 62.0
PYH2_k127_7977629_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.977e-195 619.0
PYH2_k127_7977629_1 PFAM Cytochrome c assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 440.0
PYH2_k127_7977629_10 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000006785 94.0
PYH2_k127_7977629_11 YacP-like NYN domain K06962 - - 0.000000000000072 78.0
PYH2_k127_7977629_12 Cell envelope-related transcriptional attenuator domain - - - 0.0009433 51.0
PYH2_k127_7977629_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
PYH2_k127_7977629_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000007871 255.0
PYH2_k127_7977629_4 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000142 196.0
PYH2_k127_7977629_5 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000001953 171.0
PYH2_k127_7977629_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000009853 161.0
PYH2_k127_7977629_7 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000001983 143.0
PYH2_k127_7977629_8 lyase activity - - - 0.0000000000000000000000000000001085 143.0
PYH2_k127_7977629_9 phosphorelay signal transduction system - - - 0.0000000000000000000000000008496 119.0
PYH2_k127_7980244_0 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001763 282.0
PYH2_k127_8120154_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.0 1075.0
PYH2_k127_8120154_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 312.0
PYH2_k127_8120154_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000001991 147.0
PYH2_k127_8120154_3 response regulator - - - 0.00000113 52.0
PYH2_k127_8156719_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 3.952e-314 992.0
PYH2_k127_8156719_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 399.0
PYH2_k127_8156719_10 - - - - 0.0000000000000000000000000000000000000000000008091 178.0
PYH2_k127_8156719_11 - - - - 0.0000000000003428 75.0
PYH2_k127_8156719_12 Pentapeptide repeats (9 copies) - - - 0.0001606 53.0
PYH2_k127_8156719_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001162 280.0
PYH2_k127_8156719_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003095 289.0
PYH2_k127_8156719_4 anaerobic respiration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001264 275.0
PYH2_k127_8156719_5 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001379 262.0
PYH2_k127_8156719_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001301 258.0
PYH2_k127_8156719_7 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000001677 213.0
PYH2_k127_8156719_8 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000108 206.0
PYH2_k127_8156719_9 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000003684 194.0
PYH2_k127_8314794_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 604.0
PYH2_k127_8314794_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000779 78.0
PYH2_k127_8314794_2 - - - - 0.0000003102 57.0
PYH2_k127_8365084_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002982 439.0
PYH2_k127_8365084_1 type IV pilus secretin PilQ K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004253 409.0
PYH2_k127_8365084_10 Pilus assembly protein, PilP K02665 - - 0.000000000002366 72.0
PYH2_k127_8365084_2 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001388 258.0
PYH2_k127_8365084_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 252.0
PYH2_k127_8365084_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000002206 257.0
PYH2_k127_8365084_5 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000001638 171.0
PYH2_k127_8365084_6 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000339 151.0
PYH2_k127_8365084_7 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000007998 128.0
PYH2_k127_8365084_8 Roadblock/LC7 domain - - - 0.0000000000000000000002072 101.0
PYH2_k127_8365084_9 Tetratricopeptide repeat - - - 0.0000000000000000001924 104.0
PYH2_k127_8453214_0 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006164 295.0
PYH2_k127_8453214_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000189 85.0
PYH2_k127_8453214_2 Protein of unknown function (DUF2934) - - - 0.0000000000001393 74.0
PYH2_k127_8453214_3 PilZ domain - - - 0.0000003712 55.0
PYH2_k127_8453214_4 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0002039 48.0
PYH2_k127_8481286_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 5.067e-237 748.0
PYH2_k127_8481286_1 Dehydratase family K01687 - 4.2.1.9 2.855e-216 686.0
PYH2_k127_8481286_10 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 434.0
PYH2_k127_8481286_11 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 426.0
PYH2_k127_8481286_12 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 413.0
PYH2_k127_8481286_13 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 411.0
PYH2_k127_8481286_14 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 400.0
PYH2_k127_8481286_15 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 364.0
PYH2_k127_8481286_16 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 355.0
PYH2_k127_8481286_17 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 340.0
PYH2_k127_8481286_18 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 329.0
PYH2_k127_8481286_19 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 333.0
PYH2_k127_8481286_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.954e-204 647.0
PYH2_k127_8481286_20 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 332.0
PYH2_k127_8481286_21 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 313.0
PYH2_k127_8481286_22 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 312.0
PYH2_k127_8481286_23 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 299.0
PYH2_k127_8481286_24 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008119 300.0
PYH2_k127_8481286_25 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 280.0
PYH2_k127_8481286_26 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 269.0
PYH2_k127_8481286_27 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003936 273.0
PYH2_k127_8481286_28 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000492 260.0
PYH2_k127_8481286_29 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000001165 259.0
PYH2_k127_8481286_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.659e-199 636.0
PYH2_k127_8481286_30 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000005049 240.0
PYH2_k127_8481286_31 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000001933 219.0
PYH2_k127_8481286_32 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000000005494 212.0
PYH2_k127_8481286_33 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000005268 213.0
PYH2_k127_8481286_34 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000009464 179.0
PYH2_k127_8481286_35 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000004312 187.0
PYH2_k127_8481286_36 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000001344 165.0
PYH2_k127_8481286_37 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000007314 133.0
PYH2_k127_8481286_38 - - - - 0.00000000000000000000000000002567 133.0
PYH2_k127_8481286_39 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000008812 119.0
PYH2_k127_8481286_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 605.0
PYH2_k127_8481286_40 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000004822 108.0
PYH2_k127_8481286_41 glycoprotease K14742 - - 0.00000000000000000000002573 114.0
PYH2_k127_8481286_42 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000002026 103.0
PYH2_k127_8481286_43 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000004198 89.0
PYH2_k127_8481286_44 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001933 83.0
PYH2_k127_8481286_45 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000001087 71.0
PYH2_k127_8481286_46 - - - - 0.000000000644 61.0
PYH2_k127_8481286_47 Protein of unknown function (DUF465) K09794 - - 0.0000001111 55.0
PYH2_k127_8481286_48 - - - - 0.0000001845 61.0
PYH2_k127_8481286_49 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000001848 56.0
PYH2_k127_8481286_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 569.0
PYH2_k127_8481286_50 Helix-hairpin-helix motif K02237 - - 0.00001152 56.0
PYH2_k127_8481286_51 - - - - 0.0001081 53.0
PYH2_k127_8481286_6 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 541.0
PYH2_k127_8481286_7 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 449.0
PYH2_k127_8481286_8 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 442.0
PYH2_k127_8481286_9 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 440.0
PYH2_k127_8485539_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000228 452.0
PYH2_k127_8485539_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 449.0
PYH2_k127_8485539_10 Part of a membrane complex involved in electron transport K03617 - - 0.000000007211 60.0
PYH2_k127_8485539_11 Belongs to the precorrin methyltransferase family K02303,K13542 - 2.1.1.107,4.2.1.75 0.000000009136 66.0
PYH2_k127_8485539_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 361.0
PYH2_k127_8485539_3 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 289.0
PYH2_k127_8485539_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
PYH2_k127_8485539_5 Ribonuclease HII K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000751 204.0
PYH2_k127_8485539_6 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000004116 158.0
PYH2_k127_8485539_7 large ribosomal subunit rRNA binding K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001797 146.0
PYH2_k127_8485539_8 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000005097 119.0
PYH2_k127_8485539_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000003314 125.0
PYH2_k127_8557223_0 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 464.0
PYH2_k127_8557223_1 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 467.0
PYH2_k127_8557223_10 Thioredoxin-like - - - 0.000000000000000000000000000000000181 140.0
PYH2_k127_8557223_12 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000000000000000001994 130.0
PYH2_k127_8557223_13 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000004938 115.0
PYH2_k127_8557223_14 NHL repeat - - - 0.0000000000000000000000625 115.0
PYH2_k127_8557223_15 cell redox homeostasis - - - 0.000000000000000000000296 109.0
PYH2_k127_8557223_16 PFAM UvrB UvrC protein - - - 0.000000000001774 77.0
PYH2_k127_8557223_17 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000003698 76.0
PYH2_k127_8557223_18 GDSL-like Lipase/Acylhydrolase - - - 0.00000000005929 77.0
PYH2_k127_8557223_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 412.0
PYH2_k127_8557223_20 Photosynthesis system II assembly factor YCF48 - - - 0.00007729 56.0
PYH2_k127_8557223_3 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 347.0
PYH2_k127_8557223_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 315.0
PYH2_k127_8557223_5 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 321.0
PYH2_k127_8557223_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 303.0
PYH2_k127_8557223_7 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000002102 178.0
PYH2_k127_8557223_8 Thioredoxin-like - - - 0.000000000000000000000000000000000000001811 154.0
PYH2_k127_8557223_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000007639 157.0
PYH2_k127_8573935_0 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 276.0
PYH2_k127_8573935_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002862 271.0
PYH2_k127_8573935_2 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004754 263.0
PYH2_k127_8573935_3 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000635 244.0
PYH2_k127_8573935_4 ABC-type transport system involved in lipoprotein release permease component - - - 0.000000000000000000000000000000000000000000000000000000002669 216.0
PYH2_k127_8573935_5 deaminated base DNA N-glycosylase activity K10800 - - 0.0000000000000000000000000000000000000000000003251 184.0
PYH2_k127_8573935_6 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000173 114.0
PYH2_k127_8573935_7 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000001449 111.0
PYH2_k127_8573935_8 - - - - 0.00000000000003185 86.0
PYH2_k127_8627506_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1490.0
PYH2_k127_8627506_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 1.258e-220 702.0
PYH2_k127_8627506_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001957 217.0
PYH2_k127_8627506_3 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000003752 169.0
PYH2_k127_8630033_0 COG1032 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 480.0
PYH2_k127_8630033_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 349.0
PYH2_k127_8630033_2 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000003635 269.0
PYH2_k127_8630033_3 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006017 249.0
PYH2_k127_8630033_4 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000004052 187.0
PYH2_k127_8630033_5 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000004183 179.0
PYH2_k127_8630033_6 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.0000000000000000000000000000005892 128.0
PYH2_k127_8630033_7 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000004501 117.0
PYH2_k127_8630033_8 Transmembrane and - - - 0.00000000000000439 87.0
PYH2_k127_8630033_9 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000142 82.0
PYH2_k127_8676121_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 387.0
PYH2_k127_8676121_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 291.0
PYH2_k127_8676121_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001401 193.0
PYH2_k127_8676121_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000005954 177.0
PYH2_k127_8676121_4 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000008399 164.0
PYH2_k127_8688838_0 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 606.0
PYH2_k127_8688838_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 488.0
PYH2_k127_8688838_10 Thioredoxin-like - - - 0.0000000000000000000000000000000000000546 157.0
PYH2_k127_8688838_11 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000005806 104.0
PYH2_k127_8688838_12 Class III cytochrome C family - - - 0.00000000004492 69.0
PYH2_k127_8688838_2 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 459.0
PYH2_k127_8688838_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 342.0
PYH2_k127_8688838_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 329.0
PYH2_k127_8688838_6 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 328.0
PYH2_k127_8688838_7 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 321.0
PYH2_k127_8688838_8 cellulase activity K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000003635 177.0
PYH2_k127_8688838_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000002467 169.0
PYH2_k127_8718826_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 607.0
PYH2_k127_8718826_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 595.0
PYH2_k127_8718826_10 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000003202 201.0
PYH2_k127_8718826_11 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000074 190.0
PYH2_k127_8718826_12 beta-propeller repeat - - - 0.0000000000000000000000000000000000007358 156.0
PYH2_k127_8718826_13 Met-10+ like-protein - - - 0.000000000000000000000000006894 117.0
PYH2_k127_8718826_14 protein kinase related protein - - - 0.000000000000000000000001837 119.0
PYH2_k127_8718826_15 toxin-antitoxin pair type II binding K19159 - - 0.00000000000000001655 86.0
PYH2_k127_8718826_16 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000002213 73.0
PYH2_k127_8718826_17 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000001651 74.0
PYH2_k127_8718826_18 - - - - 0.000008665 53.0
PYH2_k127_8718826_2 PQQ-like domain K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 507.0
PYH2_k127_8718826_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 419.0
PYH2_k127_8718826_4 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 391.0
PYH2_k127_8718826_5 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 370.0
PYH2_k127_8718826_6 FMN-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 364.0
PYH2_k127_8718826_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 362.0
PYH2_k127_8718826_8 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000008423 256.0
PYH2_k127_8718826_9 - K03616 - - 0.00000000000000000000000000000000000000000000000000000000002734 214.0
PYH2_k127_8728629_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 484.0
PYH2_k127_8728629_1 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 447.0
PYH2_k127_8728629_10 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000234 151.0
PYH2_k127_8728629_11 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000004668 140.0
PYH2_k127_8728629_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 421.0
PYH2_k127_8728629_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 413.0
PYH2_k127_8728629_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 359.0
PYH2_k127_8728629_5 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 316.0
PYH2_k127_8728629_6 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003095 283.0
PYH2_k127_8728629_7 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000005376 293.0
PYH2_k127_8728629_8 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003086 259.0
PYH2_k127_8728629_9 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000003545 256.0
PYH2_k127_8737256_0 General secretory system II, protein E domain protein K02652 - - 3.996e-218 692.0
PYH2_k127_8737256_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 533.0
PYH2_k127_8737256_10 Prokaryotic N-terminal methylation motif K02456,K02650 - - 0.00000001689 62.0
PYH2_k127_8737256_11 Protein of unknown function (DUF3343) - - - 0.0002242 50.0
PYH2_k127_8737256_2 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 454.0
PYH2_k127_8737256_3 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 402.0
PYH2_k127_8737256_4 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 384.0
PYH2_k127_8737256_5 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 325.0
PYH2_k127_8737256_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000001228 226.0
PYH2_k127_8737256_7 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000003048 217.0
PYH2_k127_8737256_8 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000448 194.0
PYH2_k127_8737256_9 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.00000000000006656 78.0
PYH2_k127_8778940_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 576.0
PYH2_k127_8778940_1 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 509.0
PYH2_k127_8778940_10 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000003235 150.0
PYH2_k127_8778940_11 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000711 139.0
PYH2_k127_8778940_12 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000437 127.0
PYH2_k127_8778940_13 zinc-ribbon domain - - - 0.0000000000000000000000000002162 126.0
PYH2_k127_8778940_14 Cytosol aminopeptidase family, N-terminal domain - - - 0.000000007445 66.0
PYH2_k127_8778940_2 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 316.0
PYH2_k127_8778940_3 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004892 274.0
PYH2_k127_8778940_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000001674 245.0
PYH2_k127_8778940_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
PYH2_k127_8778940_6 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000002127 209.0
PYH2_k127_8778940_7 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000677 189.0
PYH2_k127_8778940_8 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000433 198.0
PYH2_k127_8778940_9 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000005231 166.0
PYH2_k127_8779279_0 Threonine synthase K01733 - 4.2.3.1 1.172e-197 636.0
PYH2_k127_8779279_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 559.0
PYH2_k127_8779279_2 PFAM Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
PYH2_k127_8779279_3 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000003042 158.0
PYH2_k127_8779279_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.0000000000002072 74.0
PYH2_k127_8791005_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 341.0
PYH2_k127_8791005_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 350.0
PYH2_k127_8791005_2 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 288.0
PYH2_k127_8791005_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000001825 228.0
PYH2_k127_8791005_4 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004457 232.0
PYH2_k127_8791005_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000001639 221.0
PYH2_k127_8791005_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000007799 153.0
PYH2_k127_8791005_7 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000002917 109.0
PYH2_k127_8791005_8 ABC-type uncharacterized transport system - - - 0.00005188 48.0
PYH2_k127_880394_0 GAF domain - - - 0.000000000000000000000000000000000000000004719 175.0
PYH2_k127_8835965_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 3.294e-250 792.0
PYH2_k127_8835965_1 Conserved carboxylase domain K01958 - 6.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007114 559.0
PYH2_k127_8835965_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 543.0
PYH2_k127_8835965_3 PFAM YeeE YedE family (DUF395) K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 480.0
PYH2_k127_8835965_4 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000003642 186.0
PYH2_k127_8835965_5 Cold-shock protein - - - 0.0000000000000000000000008736 104.0
PYH2_k127_8835965_6 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000006827 94.0
PYH2_k127_8835965_7 - - - - 0.000000000000001318 79.0
PYH2_k127_8835965_8 Flavodoxin domain - - - 0.000001011 57.0
PYH2_k127_8863915_0 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 469.0
PYH2_k127_8863915_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 389.0
PYH2_k127_8863915_10 Redoxin - - - 0.0000000000000000000000000000339 119.0
PYH2_k127_8863915_11 MgtC family K07507 - - 0.00000000000000000000000003573 112.0
PYH2_k127_8863915_12 Thioredoxin - - - 0.00000000000000000004397 99.0
PYH2_k127_8863915_13 Uncharacterized protein family UPF0054 - - - 0.00000000000000000009967 95.0
PYH2_k127_8863915_14 Domain of unknown function (DUF1844) - - - 0.0000000000000001533 84.0
PYH2_k127_8863915_15 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000003282 82.0
PYH2_k127_8863915_16 peptidyl-tyrosine sulfation - - - 0.00000000002708 77.0
PYH2_k127_8863915_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000007718 62.0
PYH2_k127_8863915_2 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 353.0
PYH2_k127_8863915_3 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 320.0
PYH2_k127_8863915_4 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 293.0
PYH2_k127_8863915_5 SNARE associated Golgi protein K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000008467 274.0
PYH2_k127_8863915_6 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008636 254.0
PYH2_k127_8863915_7 PFAM CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000001995 237.0
PYH2_k127_8863915_8 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000002565 240.0
PYH2_k127_8863915_9 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000007331 184.0
PYH2_k127_8864874_0 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 588.0
PYH2_k127_8864874_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 338.0
PYH2_k127_8864874_2 biosynthesis protein K01104 - 3.1.3.48 0.00000000000000000009299 102.0
PYH2_k127_8864874_3 Tetratricopeptide repeats - - - 0.0000000000000000006232 97.0
PYH2_k127_8864874_4 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000003016 79.0
PYH2_k127_8864874_5 Sporulation related domain - - - 0.00006807 55.0
PYH2_k127_8945062_0 ASPIC and UnbV - - - 1.854e-196 625.0
PYH2_k127_8945062_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 497.0
PYH2_k127_8945062_10 - - - - 0.000000000000000000000002739 114.0
PYH2_k127_8945062_11 amine dehydrogenase activity - - - 0.000000000000001139 90.0
PYH2_k127_8945062_13 - - - - 0.00000000005622 67.0
PYH2_k127_8945062_14 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.0000000001018 69.0
PYH2_k127_8945062_15 nitric oxide dioxygenase activity - - - 0.0000004489 54.0
PYH2_k127_8945062_16 peptidase U32 - - - 0.00003106 56.0
PYH2_k127_8945062_2 denitrification pathway K02569,K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 492.0
PYH2_k127_8945062_3 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 379.0
PYH2_k127_8945062_4 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009154 267.0
PYH2_k127_8945062_5 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000003127 254.0
PYH2_k127_8945062_6 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000009061 238.0
PYH2_k127_8945062_7 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.000000000000000000000000000000000000000000000000001126 197.0
PYH2_k127_8945062_8 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000009693 163.0
PYH2_k127_9105160_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 603.0
PYH2_k127_9105160_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 295.0
PYH2_k127_9105160_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003331 273.0
PYH2_k127_9105160_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000005417 271.0
PYH2_k127_9105160_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000002717 187.0
PYH2_k127_9137767_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 375.0
PYH2_k127_9137767_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000003373 250.0
PYH2_k127_9137767_10 TPR repeat - - - 0.000000009711 68.0
PYH2_k127_9137767_11 iron ion homeostasis - - - 0.00002146 55.0
PYH2_k127_9137767_12 OmpA family - - - 0.00002407 57.0
PYH2_k127_9137767_13 fumarate reductase K00239 - 1.3.5.1,1.3.5.4 0.00004236 55.0
PYH2_k127_9137767_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000002212 184.0
PYH2_k127_9137767_3 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000000000000000000000000000002242 186.0
PYH2_k127_9137767_4 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000001555 188.0
PYH2_k127_9137767_5 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000007685 146.0
PYH2_k127_9137767_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000009619 128.0
PYH2_k127_9137767_7 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.000000000000000003513 98.0
PYH2_k127_9137767_8 Bacterial regulatory proteins, crp family K10914 - - 0.00000000007033 68.0
PYH2_k127_9137767_9 Biopolymer transport protein ExbD/TolR - - - 0.000000000323 68.0
PYH2_k127_998012_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.287e-261 851.0
PYH2_k127_998012_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 552.0
PYH2_k127_998012_10 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 293.0
PYH2_k127_998012_11 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005408 276.0
PYH2_k127_998012_12 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 270.0
PYH2_k127_998012_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002192 256.0
PYH2_k127_998012_14 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000004628 266.0
PYH2_k127_998012_15 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
PYH2_k127_998012_16 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
PYH2_k127_998012_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000002471 225.0
PYH2_k127_998012_18 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000001197 213.0
PYH2_k127_998012_19 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000002816 203.0
PYH2_k127_998012_2 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 538.0
PYH2_k127_998012_20 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000001685 189.0
PYH2_k127_998012_21 denitrification pathway K02569,K15876 - - 0.00000000000000000000000000000000000000000000000006994 190.0
PYH2_k127_998012_22 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000001452 189.0
PYH2_k127_998012_23 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000005897 167.0
PYH2_k127_998012_24 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K01256,K02563,K02652,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 0.000000000000000000000000000000000000000000005963 179.0
PYH2_k127_998012_25 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000001386 165.0
PYH2_k127_998012_26 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000003035 149.0
PYH2_k127_998012_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000001615 135.0
PYH2_k127_998012_28 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000008037 130.0
PYH2_k127_998012_29 Belongs to the P(II) protein family - - - 0.0000000000000000000000002129 109.0
PYH2_k127_998012_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 501.0
PYH2_k127_998012_30 peptidyl-prolyl cis-trans isomerase activity K02597,K03769,K03771 - 5.2.1.8 0.0000000000000000000009574 107.0
PYH2_k127_998012_31 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000003173 92.0
PYH2_k127_998012_32 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.00000000001654 68.0
PYH2_k127_998012_33 PFAM RNA-binding S4 domain protein - - - 0.00000000007033 68.0
PYH2_k127_998012_34 PilZ domain - - - 0.0000000007749 64.0
PYH2_k127_998012_35 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000002713 57.0
PYH2_k127_998012_4 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 432.0
PYH2_k127_998012_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 393.0
PYH2_k127_998012_6 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 343.0
PYH2_k127_998012_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 342.0
PYH2_k127_998012_8 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 320.0
PYH2_k127_998012_9 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 297.0