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Overview

ID MAG03204
Name PYH2_bin.63
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order Dehalococcoidales
Family Fen-1064
Genus JAURWL01
Species
Assembly information
Completeness (%) 98.94
Contamination (%) 4.81
GC content (%) 52.0
N50 (bp) 11,393
Genome size (bp) 2,406,511

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2365

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1028416_0 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 339.0
PYH2_k127_1028416_1 Protein of unknown function (DUF1566) - - - 0.000000000000000001815 100.0
PYH2_k127_1033683_0 nitronate monooxygenase activity K00088,K00459 - 1.1.1.205,1.13.12.16 3.479e-293 905.0
PYH2_k127_1033683_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 5.461e-222 700.0
PYH2_k127_1033683_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000838 145.0
PYH2_k127_1033683_11 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000008351 90.0
PYH2_k127_1033683_12 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000004062 80.0
PYH2_k127_1033683_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 9.499e-195 624.0
PYH2_k127_1033683_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 419.0
PYH2_k127_1033683_4 Ribonuclease R winged-helix domain K09720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 374.0
PYH2_k127_1033683_5 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007657 355.0
PYH2_k127_1033683_6 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 349.0
PYH2_k127_1033683_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000002691 205.0
PYH2_k127_1033683_8 PFAM molybdopterin oxidoreductase K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000002224 189.0
PYH2_k127_1033683_9 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000001482 173.0
PYH2_k127_1044716_0 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 403.0
PYH2_k127_1044716_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 308.0
PYH2_k127_1044716_10 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000004359 203.0
PYH2_k127_1044716_11 Cytochrome c3 - - - 0.00000000000000000000000000000000001504 148.0
PYH2_k127_1044716_12 Response regulator receiver K07696 - - 0.0000000000000000000007766 103.0
PYH2_k127_1044716_13 Belongs to the peptidase M50B family - - - 0.000000000000000000466 96.0
PYH2_k127_1044716_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000001615 76.0
PYH2_k127_1044716_16 Carboxypeptidase regulatory-like domain - - - 0.000009392 54.0
PYH2_k127_1044716_17 acetyl-coa acetyltransferase - - - 0.00003161 49.0
PYH2_k127_1044716_2 Polysulphide reductase K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 294.0
PYH2_k127_1044716_3 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006221 258.0
PYH2_k127_1044716_4 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001028 268.0
PYH2_k127_1044716_5 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006143 257.0
PYH2_k127_1044716_6 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007577 271.0
PYH2_k127_1044716_7 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000001214 235.0
PYH2_k127_1044716_8 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000002797 213.0
PYH2_k127_1044716_9 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.0000000000000000000000000000000000000000000000000000005548 201.0
PYH2_k127_1046126_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.0 1063.0
PYH2_k127_1046126_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.928e-307 954.0
PYH2_k127_1046126_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000247 138.0
PYH2_k127_1046126_11 COG0515 Serine threonine protein K12132 - 2.7.11.1 0.000000000000001811 87.0
PYH2_k127_1046126_12 PFAM Cyclic nucleotide-binding domain - - - 0.000000000000007939 81.0
PYH2_k127_1046126_2 HMGL-like K02594 - 2.3.3.14 1.44e-202 639.0
PYH2_k127_1046126_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 588.0
PYH2_k127_1046126_4 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 512.0
PYH2_k127_1046126_5 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 347.0
PYH2_k127_1046126_6 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
PYH2_k127_1046126_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000007654 252.0
PYH2_k127_1046126_8 Protein of unknown function (DUF1638) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001164 249.0
PYH2_k127_1046126_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000001057 156.0
PYH2_k127_1080163_0 NAD synthase K01916 - 6.3.1.5 4e-213 674.0
PYH2_k127_1080163_1 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 455.0
PYH2_k127_1080163_10 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000003483 237.0
PYH2_k127_1080163_11 SMART regulatory protein, Crp K07730 - - 0.00000000000000000000000000000000000000000000000000000000004907 215.0
PYH2_k127_1080163_12 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000634 209.0
PYH2_k127_1080163_13 Metallo-beta-lactamase superfamily K01069 GO:0003674,GO:0005488,GO:0008270,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.1.2.6 0.0000000000000000000000000000001319 131.0
PYH2_k127_1080163_14 Belongs to the 2H phosphoesterase superfamily. YjcG family - - - 0.00000003695 62.0
PYH2_k127_1080163_15 - - - - 0.000144 50.0
PYH2_k127_1080163_2 PFAM acyl-CoA dehydrogenase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009232 421.0
PYH2_k127_1080163_3 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 415.0
PYH2_k127_1080163_4 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 414.0
PYH2_k127_1080163_5 Beta-ketoacyl synthase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 406.0
PYH2_k127_1080163_6 FecCD transport family K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 370.0
PYH2_k127_1080163_7 Family of unknown function (DUF438) K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 349.0
PYH2_k127_1080163_8 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004231 336.0
PYH2_k127_1080163_9 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 287.0
PYH2_k127_110028_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 619.0
PYH2_k127_110028_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000957 254.0
PYH2_k127_110028_2 domain, Protein K21449 - - 0.00000000000000000000000000000000000000000001861 188.0
PYH2_k127_110028_3 - - - - 0.0000000000000000000000000000000000000003197 164.0
PYH2_k127_110028_4 TIGRFAM polymorphic outer membrane protein K21449 - - 0.000000000000000000000000000000000000001114 173.0
PYH2_k127_1104130_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001181 278.0
PYH2_k127_1104130_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000611 156.0
PYH2_k127_1122669_0 Domain of unknown function (DUF1998) K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 378.0
PYH2_k127_1122669_1 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000000000003123 187.0
PYH2_k127_1122669_2 Protein conserved in bacteria K09764 - - 0.0000000000000000001294 91.0
PYH2_k127_1122669_3 Helix-turn-helix - - - 0.0000000000000000005606 88.0
PYH2_k127_1128642_0 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000003946 212.0
PYH2_k127_1128642_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000004758 178.0
PYH2_k127_1128642_2 B12 binding domain - - - 0.000173 47.0
PYH2_k127_114195_0 Multicopper oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 409.0
PYH2_k127_114195_1 Metallo-peptidase family M12 - - - 0.00000000000003852 86.0
PYH2_k127_114195_2 Belongs to the peptidase S8 family - - - 0.0000000000004742 82.0
PYH2_k127_114195_3 sequence-specific DNA binding K18830 - - 0.00000000002157 64.0
PYH2_k127_11595_0 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 587.0
PYH2_k127_1163935_0 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 347.0
PYH2_k127_1163935_1 Transposase DNA-binding - - - 0.000000002875 59.0
PYH2_k127_1174785_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000475 561.0
PYH2_k127_1174785_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 334.0
PYH2_k127_1174785_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
PYH2_k127_1174785_3 Putative esterase K07214 - - 0.00000000000000000000000000000000000000000000000000000000000001696 222.0
PYH2_k127_1174785_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000007496 216.0
PYH2_k127_1174785_5 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000001098 82.0
PYH2_k127_1174785_6 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000002346 82.0
PYH2_k127_1174785_7 Peptide ABC transporter substrate-binding protein K02035 - - 0.00002568 49.0
PYH2_k127_1181602_0 Aromatic ring hydroxylase K14534 - 4.2.1.120,5.3.3.3 9.772e-205 651.0
PYH2_k127_1181602_1 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 466.0
PYH2_k127_1181602_2 SERine Proteinase INhibitors K13963 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 460.0
PYH2_k127_1181602_3 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000001028 176.0
PYH2_k127_1181602_4 Domain of unknown function (DUF4157) - - - 0.000000000000000000000000000000000000005469 166.0
PYH2_k127_1181602_5 Peptidase S9, prolyl oligopeptidase active site domain protein - - - 0.0000000000000000000000000000000000215 143.0
PYH2_k127_1181602_6 Domain of unknown function (DUF4159) - - - 0.0000000000000000000000000000002717 138.0
PYH2_k127_1181602_7 cell adhesion involved in biofilm formation - - - 0.0000000000000000006949 101.0
PYH2_k127_1181602_8 Pkd domain containing protein - - - 0.00000000004054 76.0
PYH2_k127_1181602_9 PFAM Phage tail protein (Tail_P2_I) - - - 0.0004424 45.0
PYH2_k127_121688_0 Hydantoinase/oxoprolinase N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 565.0
PYH2_k127_121688_1 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 505.0
PYH2_k127_121688_2 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002569 272.0
PYH2_k127_121688_3 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000001314 257.0
PYH2_k127_121688_4 methionine synthase K00548 - 2.1.1.13 0.0005298 45.0
PYH2_k127_1223608_0 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000006225 213.0
PYH2_k127_1223608_1 sAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000000001822 184.0
PYH2_k127_1229577_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000002667 197.0
PYH2_k127_1229577_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000000000000000000000004666 128.0
PYH2_k127_1229577_2 Domain of unknown function (DU1801) - - - 0.0000000000000002271 83.0
PYH2_k127_1260926_0 alcohol dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 317.0
PYH2_k127_1260926_1 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 297.0
PYH2_k127_1260926_10 ABC-2 family transporter protein - - - 0.000000000000000000000002654 112.0
PYH2_k127_1260926_2 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000497 297.0
PYH2_k127_1260926_3 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008983 286.0
PYH2_k127_1260926_4 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005468 281.0
PYH2_k127_1260926_5 Epoxide hydrolase 2 K08726,K10089 GO:0000287,GO:0001676,GO:0002532,GO:0002538,GO:0002539,GO:0003008,GO:0003013,GO:0003018,GO:0003674,GO:0003824,GO:0004301,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006605,GO:0006625,GO:0006629,GO:0006631,GO:0006633,GO:0006690,GO:0006725,GO:0006793,GO:0006796,GO:0006805,GO:0006810,GO:0006873,GO:0006874,GO:0006875,GO:0006886,GO:0006950,GO:0006952,GO:0006954,GO:0006996,GO:0007031,GO:0007600,GO:0008015,GO:0008104,GO:0008150,GO:0008152,GO:0008217,GO:0008610,GO:0009056,GO:0009058,GO:0009410,GO:0009636,GO:0009810,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0015031,GO:0015643,GO:0015833,GO:0016043,GO:0016053,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016801,GO:0016803,GO:0017144,GO:0018904,GO:0019216,GO:0019218,GO:0019222,GO:0019233,GO:0019369,GO:0019373,GO:0019439,GO:0019725,GO:0019752,GO:0030003,GO:0030258,GO:0031907,GO:0031974,GO:0032501,GO:0032787,GO:0033036,GO:0033365,GO:0033559,GO:0034613,GO:0035150,GO:0035296,GO:0042221,GO:0042577,GO:0042578,GO:0042579,GO:0042592,GO:0042632,GO:0042759,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043651,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045777,GO:0046272,GO:0046394,GO:0046483,GO:0046839,GO:0046872,GO:0046907,GO:0046983,GO:0048518,GO:0048878,GO:0050789,GO:0050801,GO:0050877,GO:0050880,GO:0050896,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0051716,GO:0055065,GO:0055074,GO:0055080,GO:0055082,GO:0055088,GO:0055092,GO:0060255,GO:0062012,GO:0065007,GO:0065008,GO:0070013,GO:0070727,GO:0070887,GO:0071466,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072330,GO:0072503,GO:0072507,GO:0072593,GO:0072594,GO:0072662,GO:0072663,GO:0080090,GO:0090066,GO:0090181,GO:0097176,GO:0097746,GO:0097755,GO:0098771,GO:1900673,GO:1901360,GO:1901361,GO:1901568,GO:1901575,GO:1901576 3.1.3.76,3.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000001105 272.0
PYH2_k127_1260926_6 dehydratase K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000001413 256.0
PYH2_k127_1260926_7 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000001198 221.0
PYH2_k127_1260926_8 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000381 197.0
PYH2_k127_1260926_9 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000002645 139.0
PYH2_k127_1278141_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 400.0
PYH2_k127_1278141_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 335.0
PYH2_k127_1278141_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000002592 150.0
PYH2_k127_130101_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000529 488.0
PYH2_k127_1316131_0 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 295.0
PYH2_k127_1319025_0 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 6.231e-210 677.0
PYH2_k127_1319025_1 formate C-acetyltransferase glycine radical K00656 - 2.3.1.54 2.06e-209 676.0
PYH2_k127_1319025_2 Alcohol dehydrogenase GroES-like domain K00008,K00094 - 1.1.1.14,1.1.1.251 0.00000000000000000000000000000000000000000000000000000000004305 218.0
PYH2_k127_1319025_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000004893 214.0
PYH2_k127_1319025_4 COG COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases K00008 - 1.1.1.14 0.0000000000000000000000000000000005927 145.0
PYH2_k127_1319025_5 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.000000000000000000000000000000001692 138.0
PYH2_k127_1319025_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000001101 82.0
PYH2_k127_1319025_7 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.000000000000287 75.0
PYH2_k127_1327665_0 sh3 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001145 251.0
PYH2_k127_1327665_1 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.00000000000000000000000000000000000000000000000001037 187.0
PYH2_k127_1336709_0 - - - - 0.000000000000000000000000000000000001424 146.0
PYH2_k127_1336709_1 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000005561 118.0
PYH2_k127_1341384_0 endopeptidase inhibitor activity K06530 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 454.0
PYH2_k127_1341384_1 AIR synthase related protein, C-terminal domain K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 385.0
PYH2_k127_1345174_0 von Willebrand factor (vWF) type A domain K07114 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 367.0
PYH2_k127_1345174_1 CoA binding domain - - - 0.00000000000000000000000000000000000001106 156.0
PYH2_k127_136522_0 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 424.0
PYH2_k127_136522_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000045 409.0
PYH2_k127_136522_2 leucine import across plasma membrane K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 310.0
PYH2_k127_136522_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000008919 172.0
PYH2_k127_1370588_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 385.0
PYH2_k127_1370588_1 GyrI-like small molecule binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003417 281.0
PYH2_k127_1370588_2 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004625 243.0
PYH2_k127_1370588_3 - - - - 0.000000000000000000000000000000000000000000000000000009552 192.0
PYH2_k127_1370588_4 N,N-dimethylaniline monooxygenase activity K07222 - - 0.0000000000000000000000000000000002316 141.0
PYH2_k127_1374711_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.111e-259 816.0
PYH2_k127_1374711_1 Acetyl-CoA acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 469.0
PYH2_k127_1374711_10 acetoacetate decarboxylase activity K01574 - 4.1.1.4 0.00000000000000000000000000000000002586 138.0
PYH2_k127_1374711_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003388 142.0
PYH2_k127_1374711_13 nitrite transmembrane transporter activity K02575,K08223 - - 0.00000000000001492 86.0
PYH2_k127_1374711_14 Major Facilitator Superfamily K03535,K08194 - - 0.000000000001349 79.0
PYH2_k127_1374711_15 - - - - 0.00004389 46.0
PYH2_k127_1374711_2 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 418.0
PYH2_k127_1374711_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 405.0
PYH2_k127_1374711_4 PFAM Transketolase K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 376.0
PYH2_k127_1374711_5 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005658 326.0
PYH2_k127_1374711_6 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008821 310.0
PYH2_k127_1374711_7 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003384 257.0
PYH2_k127_1374711_8 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.0000000000000000000000000000000000000000000006338 173.0
PYH2_k127_1374711_9 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.00000000000000000000000000000000000000008417 154.0
PYH2_k127_1392634_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 384.0
PYH2_k127_1392634_1 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000004617 83.0
PYH2_k127_142403_0 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 342.0
PYH2_k127_142403_1 Rossmann-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004975 286.0
PYH2_k127_142403_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000003291 235.0
PYH2_k127_142403_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000001368 154.0
PYH2_k127_142403_4 Glutaredoxin K03676,K04771 - 3.4.21.107 0.00000000000000000000000000000000001383 141.0
PYH2_k127_142403_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000008742 67.0
PYH2_k127_142403_6 PFAM Cyclic nucleotide-binding K10914 - - 0.000000007407 57.0
PYH2_k127_1459954_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006124 342.0
PYH2_k127_1459954_1 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.0000000000000000000000000000000000000000000000000000001462 203.0
PYH2_k127_1459954_2 pfam nudix - - - 0.000000000000000000000000000000000000004432 151.0
PYH2_k127_1459954_3 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000000002573 105.0
PYH2_k127_1459954_4 involved in chromosome partitioning - - - 0.000000002435 68.0
PYH2_k127_1500300_0 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000003451 128.0
PYH2_k127_1500300_1 Helix-turn-helix domain - - - 0.0000000000000000000000007696 112.0
PYH2_k127_1500300_2 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000005335 106.0
PYH2_k127_152561_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 1.098e-217 686.0
PYH2_k127_152561_1 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 569.0
PYH2_k127_152561_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003717 434.0
PYH2_k127_152561_3 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006438 311.0
PYH2_k127_152561_4 Peptidase S15 K06978 - - 0.000000000000000000000000000000000000000000000000000002099 201.0
PYH2_k127_152561_5 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily K02617 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008270,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043168,GO:0043169,GO:0043199,GO:0046872,GO:0046914,GO:0050897,GO:0071890,GO:1901681 - 0.0000000000000000000000000000000000002542 146.0
PYH2_k127_152561_6 Thioredoxin - - - 0.0000000000000000000000000001525 123.0
PYH2_k127_152561_7 TM2 domain - - - 0.000000000000672 73.0
PYH2_k127_152561_8 Glutaredoxin - - - 0.00008505 48.0
PYH2_k127_1531239_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 350.0
PYH2_k127_1531239_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003891 238.0
PYH2_k127_1531239_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000007404 218.0
PYH2_k127_1531239_3 FAD linked oxidases, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000002023 225.0
PYH2_k127_1531239_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000004099 214.0
PYH2_k127_165699_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K05587,K18331 - 1.12.1.3,1.6.5.3 6.216e-233 735.0
PYH2_k127_165699_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003131 312.0
PYH2_k127_165699_2 CoA binding domain - - - 0.00000000000000000000000000000000000000000000000000000000001441 224.0
PYH2_k127_165699_3 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.0000000000000000000000000000000000000000000009042 173.0
PYH2_k127_165699_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334,K03388 - 1.6.5.3,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000007935 138.0
PYH2_k127_165699_5 Acyltransferase family K11941 - - 0.0000000000000000000000000000000002991 147.0
PYH2_k127_165699_6 sequence-specific DNA binding - - - 0.0001919 44.0
PYH2_k127_1667815_0 - - - - 0.0000000000000000000000000000000000000000000000004085 187.0
PYH2_k127_1667815_1 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000001076 132.0
PYH2_k127_1667815_2 OsmC-like protein K07397 - - 0.000000000000000000003776 101.0
PYH2_k127_1670566_0 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000000000000000000000005346 130.0
PYH2_k127_1682938_0 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 419.0
PYH2_k127_1682938_1 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000007613 235.0
PYH2_k127_1682938_2 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000000000000000002489 210.0
PYH2_k127_1689511_0 MaoC like domain - - - 0.00000000000000000000000000000001983 131.0
PYH2_k127_1689511_1 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000003533 105.0
PYH2_k127_1689511_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000886 48.0
PYH2_k127_1734301_0 binding domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 9.11e-260 833.0
PYH2_k127_1734301_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.646e-233 738.0
PYH2_k127_1734301_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.861e-222 710.0
PYH2_k127_1734301_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002553 446.0
PYH2_k127_1734301_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 300.0
PYH2_k127_1734301_5 4Fe-4S dicluster domain K00125,K03646 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 296.0
PYH2_k127_1734301_6 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000008022 203.0
PYH2_k127_1734301_7 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000004606 188.0
PYH2_k127_1734301_8 4Fe-4S dicluster domain K03390,K16887 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000007663 165.0
PYH2_k127_1743122_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 400.0
PYH2_k127_1743122_1 - - - - 0.00000005178 57.0
PYH2_k127_175884_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000001294 199.0
PYH2_k127_175884_1 PFAM DegV family protein - - - 0.0000000000000000000000000005793 117.0
PYH2_k127_1777093_0 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 351.0
PYH2_k127_1799698_0 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 477.0
PYH2_k127_1799698_1 4-Oxalocrotonate Tautomerase - - - 0.00000000005386 65.0
PYH2_k127_1816775_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 303.0
PYH2_k127_1816775_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002414 282.0
PYH2_k127_1816775_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000005531 114.0
PYH2_k127_1830221_0 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000001308 93.0
PYH2_k127_1832225_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 374.0
PYH2_k127_1832225_1 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003299 280.0
PYH2_k127_1832225_2 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000009866 75.0
PYH2_k127_183661_0 Involved in initiation control of chromosome replication - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004932 417.0
PYH2_k127_183661_1 Putative cyclase K00036,K07130 - 1.1.1.363,1.1.1.49,3.5.1.9 0.00000000000001759 73.0
PYH2_k127_1868758_0 DNA-directed DNA polymerase K00960,K02337,K14162 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0030312,GO:0031668,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0042221,GO:0042276,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044464,GO:0046483,GO:0046677,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071897,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.6,2.7.7.7 0.0 1545.0
PYH2_k127_1868758_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001341 555.0
PYH2_k127_1868758_10 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K17735 - 1.1.1.108,1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000005561 248.0
PYH2_k127_1868758_11 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003889 246.0
PYH2_k127_1868758_12 Fumarase C-terminus K01678 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000002494 233.0
PYH2_k127_1868758_13 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000001323 226.0
PYH2_k127_1868758_14 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000002201 209.0
PYH2_k127_1868758_15 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000003548 194.0
PYH2_k127_1868758_16 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000001699 170.0
PYH2_k127_1868758_17 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000003828 173.0
PYH2_k127_1868758_18 Enoyl-(Acyl carrier protein) reductase K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000312 162.0
PYH2_k127_1868758_2 Fumarate hydratase (Fumerase) K01677 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 358.0
PYH2_k127_1868758_20 Serine threonine protein kinase K08884 - 2.7.11.1 0.000000000000000000000000000000000000001798 171.0
PYH2_k127_1868758_21 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000006082 149.0
PYH2_k127_1868758_22 - - - - 0.0000000000000000000000000000000002139 144.0
PYH2_k127_1868758_23 Peptidase family M54 K06974 - - 0.0000000000000000000000000000001014 132.0
PYH2_k127_1868758_24 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000003811 134.0
PYH2_k127_1868758_25 - - - - 0.00000000000000000000000000003389 125.0
PYH2_k127_1868758_26 - - - - 0.000000000000000000000000002801 113.0
PYH2_k127_1868758_27 PFAM ABC-2 type transporter K01992 - - 0.000000000000000005813 96.0
PYH2_k127_1868758_28 - - - - 0.00000000001318 67.0
PYH2_k127_1868758_29 Serine/threonine phosphatases, family 2C, catalytic domain K01090,K20074 - 3.1.3.16 0.00001261 49.0
PYH2_k127_1868758_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006097 354.0
PYH2_k127_1868758_4 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 349.0
PYH2_k127_1868758_5 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 321.0
PYH2_k127_1868758_6 CoA binding domain K01905 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 330.0
PYH2_k127_1868758_7 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 299.0
PYH2_k127_1868758_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001131 274.0
PYH2_k127_1868758_9 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004204 263.0
PYH2_k127_1875171_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007767 272.0
PYH2_k127_1875171_1 cheY-homologous receiver domain - - - 0.0000000000000000000000000000004435 125.0
PYH2_k127_1880827_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 3.463e-298 934.0
PYH2_k127_1880827_1 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 5.804e-293 919.0
PYH2_k127_1880827_10 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 356.0
PYH2_k127_1880827_11 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 332.0
PYH2_k127_1880827_12 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 351.0
PYH2_k127_1880827_13 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006446 326.0
PYH2_k127_1880827_14 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 307.0
PYH2_k127_1880827_15 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007474 300.0
PYH2_k127_1880827_16 4 iron, 4 sulfur cluster binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 301.0
PYH2_k127_1880827_17 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 288.0
PYH2_k127_1880827_18 PFAM 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000002146 254.0
PYH2_k127_1880827_19 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001661 237.0
PYH2_k127_1880827_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.538e-236 745.0
PYH2_k127_1880827_20 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000009997 199.0
PYH2_k127_1880827_21 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000003602 199.0
PYH2_k127_1880827_22 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000009177 196.0
PYH2_k127_1880827_23 - K07018 - - 0.00000000000000000000000000000000000000000000003817 179.0
PYH2_k127_1880827_24 GPR1/FUN34/yaaH family K07034 - - 0.00000000000000000000000000000000000000002318 158.0
PYH2_k127_1880827_25 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.00000000000000000000000000000000000002129 148.0
PYH2_k127_1880827_26 Enoyl-CoA hydratase/isomerase K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000004789 148.0
PYH2_k127_1880827_27 FMN-dependent dehydrogenase K00459 - 1.13.12.16 0.00000000000000000000000000000000001905 147.0
PYH2_k127_1880827_28 Oxidoreductase NAD-binding domain K15765 - 1.18.1.3 0.0000000000000000000000000000109 123.0
PYH2_k127_1880827_29 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.00000000000000000000003184 108.0
PYH2_k127_1880827_3 hydrogenase large subunit K00436,K14126 - 1.12.1.2,1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005855 572.0
PYH2_k127_1880827_30 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000000000002441 101.0
PYH2_k127_1880827_31 methylmalonyl-CoA epimerase K05606 - 5.1.99.1 0.0000000000000000000005793 100.0
PYH2_k127_1880827_32 Protein of unknown function (DUF664) - - - 0.000000000000000001499 92.0
PYH2_k127_1880827_33 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000004897 83.0
PYH2_k127_1880827_34 His Kinase A (phosphoacceptor) domain - - - 0.000000000000001969 86.0
PYH2_k127_1880827_35 Major Facilitator Superfamily - - - 0.000000000000241 82.0
PYH2_k127_1880827_36 Formyl transferase - - - 0.00000000008652 64.0
PYH2_k127_1880827_37 Phospholipase_D-nuclease N-terminal - - - 0.0006972 44.0
PYH2_k127_1880827_4 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 559.0
PYH2_k127_1880827_5 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 531.0
PYH2_k127_1880827_6 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 480.0
PYH2_k127_1880827_7 Radical SAM superfamily K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000024 459.0
PYH2_k127_1880827_8 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 378.0
PYH2_k127_1880827_9 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 367.0
PYH2_k127_1925942_0 peptidase activity, acting on L-amino acid peptides - - - 0.0000000000000006775 91.0
PYH2_k127_1962738_0 regulation of response to stimulus K13730 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007222 447.0
PYH2_k127_1962738_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 312.0
PYH2_k127_1962738_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000022 248.0
PYH2_k127_1962738_3 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000006109 233.0
PYH2_k127_1962738_4 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000003441 239.0
PYH2_k127_1962738_5 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000528 204.0
PYH2_k127_1962738_6 CAAX protease self-immunity K07052 - - 0.000000000000000001188 89.0
PYH2_k127_1962738_7 - - - - 0.000000000000000007542 89.0
PYH2_k127_1964568_1 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000007564 86.0
PYH2_k127_1964568_2 metallocarboxypeptidase activity K00368,K22348,K22349 - 1.16.3.3,1.7.2.1 0.00000000000000007952 88.0
PYH2_k127_1964568_3 PFAM SMP-30 Gluconolaconase - - - 0.0000113 55.0
PYH2_k127_1981799_0 amine dehydrogenase activity - - - 0.00000000000007042 81.0
PYH2_k127_2003837_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 8.533e-216 679.0
PYH2_k127_2003837_1 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 1.085e-197 627.0
PYH2_k127_2003837_10 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.0000000000000000000000000000000000000000005376 160.0
PYH2_k127_2003837_11 AMP binding - - - 0.00000000000000000000000000001124 124.0
PYH2_k127_2003837_12 PFAM Archease protein family (DUF101 UPF0211) - - - 0.00000000000000000000000000001374 122.0
PYH2_k127_2003837_13 peptidase U32 - - - 0.00000000000000000000000004012 109.0
PYH2_k127_2003837_14 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000001737 108.0
PYH2_k127_2003837_15 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000004278 98.0
PYH2_k127_2003837_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 536.0
PYH2_k127_2003837_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 523.0
PYH2_k127_2003837_4 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009118 444.0
PYH2_k127_2003837_5 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 297.0
PYH2_k127_2003837_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000006335 236.0
PYH2_k127_2003837_7 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000008026 235.0
PYH2_k127_2003837_8 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000006862 222.0
PYH2_k127_2003837_9 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000009395 213.0
PYH2_k127_2015654_0 Elongator protein 3, MiaB family, Radical SAM - - - 3.779e-232 734.0
PYH2_k127_2015654_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 300.0
PYH2_k127_2015654_2 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002088 292.0
PYH2_k127_2015654_3 Zinc ribbon domain - - - 0.0000000000013 70.0
PYH2_k127_2030832_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 595.0
PYH2_k127_2030832_1 Binding-protein-dependent transport system inner membrane component K15581 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 350.0
PYH2_k127_2045941_0 - - - - 0.00000000004313 68.0
PYH2_k127_2045941_1 Carboxylesterase family - - - 0.0000003106 59.0
PYH2_k127_2069004_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 7.084e-286 889.0
PYH2_k127_2069004_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 621.0
PYH2_k127_2069004_10 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000001236 183.0
PYH2_k127_2069004_11 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.0000000000000000000000000000000000000000004051 158.0
PYH2_k127_2069004_12 hydrogenase maturation protease K03605 - - 0.000000000000000000000000000001095 126.0
PYH2_k127_2069004_13 Response regulator receiver domain K02658 - - 0.0000006942 58.0
PYH2_k127_2069004_2 Elongation factor SelB, winged helix K03833 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 592.0
PYH2_k127_2069004_3 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 542.0
PYH2_k127_2069004_4 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 448.0
PYH2_k127_2069004_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006682 415.0
PYH2_k127_2069004_6 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002881 299.0
PYH2_k127_2069004_7 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001252 263.0
PYH2_k127_2069004_8 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000001456 234.0
PYH2_k127_2069004_9 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004043 229.0
PYH2_k127_2095853_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 389.0
PYH2_k127_2095853_1 - - - - 0.000000000000000000000000000000000000000003119 158.0
PYH2_k127_2107220_0 Rhodopirellula transposase family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 398.0
PYH2_k127_2108505_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 559.0
PYH2_k127_2108505_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006453 541.0
PYH2_k127_2108505_10 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000006993 248.0
PYH2_k127_2108505_11 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000002046 247.0
PYH2_k127_2108505_12 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001709 254.0
PYH2_k127_2108505_13 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000001584 235.0
PYH2_k127_2108505_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000001344 232.0
PYH2_k127_2108505_15 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000000000000000000000000000000000000000000001482 219.0
PYH2_k127_2108505_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000006243 218.0
PYH2_k127_2108505_17 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000138 198.0
PYH2_k127_2108505_18 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000636 195.0
PYH2_k127_2108505_19 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000007936 189.0
PYH2_k127_2108505_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 420.0
PYH2_k127_2108505_20 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000003643 179.0
PYH2_k127_2108505_21 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000005207 175.0
PYH2_k127_2108505_22 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000003612 170.0
PYH2_k127_2108505_23 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000004908 170.0
PYH2_k127_2108505_24 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000003026 165.0
PYH2_k127_2108505_25 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000002994 161.0
PYH2_k127_2108505_26 binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000002216 160.0
PYH2_k127_2108505_27 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000002744 160.0
PYH2_k127_2108505_28 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000007113 155.0
PYH2_k127_2108505_29 structural constituent of ribosome K02879 - - 0.00000000000000000000000000000000000000002705 154.0
PYH2_k127_2108505_3 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 377.0
PYH2_k127_2108505_30 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001504 147.0
PYH2_k127_2108505_31 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000001626 137.0
PYH2_k127_2108505_32 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.0000000000000000000000000000000009395 134.0
PYH2_k127_2108505_33 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000002183 127.0
PYH2_k127_2108505_34 Ribosomal protein S16 K02959 - - 0.000000000000000000000000000003628 121.0
PYH2_k127_2108505_35 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000007512 121.0
PYH2_k127_2108505_36 Transcriptional regulator PadR-like family - - - 0.000000000000000000000000004259 113.0
PYH2_k127_2108505_37 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000001893 111.0
PYH2_k127_2108505_38 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000001181 107.0
PYH2_k127_2108505_39 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000003057 103.0
PYH2_k127_2108505_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004558 365.0
PYH2_k127_2108505_40 KH domain K06960 - - 0.0000000000000000000000551 102.0
PYH2_k127_2108505_41 - - - - 0.000000000000000000002686 100.0
PYH2_k127_2108505_42 Phosphoesterase K07095 - - 0.00000000000000000004191 96.0
PYH2_k127_2108505_43 Ribosomal protein L30 K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000002443 87.0
PYH2_k127_2108505_44 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000009374 68.0
PYH2_k127_2108505_45 structural constituent of ribosome K02904 - - 0.00000000008804 64.0
PYH2_k127_2108505_5 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 314.0
PYH2_k127_2108505_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 302.0
PYH2_k127_2108505_7 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005172 283.0
PYH2_k127_2108505_8 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001577 254.0
PYH2_k127_2108505_9 endonuclease III K07457 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000069 256.0
PYH2_k127_211242_0 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000003767 198.0
PYH2_k127_211242_1 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP - - - 0.00003019 56.0
PYH2_k127_2143807_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000005993 240.0
PYH2_k127_2143807_1 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000002637 185.0
PYH2_k127_2143807_2 Chagasin family peptidase inhibitor I42 K14475 - - 0.0000000000000001375 89.0
PYH2_k127_2143807_3 Putative auto-transporter adhesin, head GIN domain - - - 0.000000000000000276 83.0
PYH2_k127_2143807_4 Protein of unknown function (DUF998) - - - 0.00005438 54.0
PYH2_k127_2151596_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 6.241e-195 616.0
PYH2_k127_2151596_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 530.0
PYH2_k127_2151596_10 - - - - 0.0000000000000005399 82.0
PYH2_k127_2151596_11 PFAM Integrase catalytic region K07497 - - 0.000000000007863 65.0
PYH2_k127_2151596_12 Hint domain - - - 0.000128 53.0
PYH2_k127_2151596_13 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0002425 44.0
PYH2_k127_2151596_2 DNA methylase K00571,K00590 - 2.1.1.113,2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 385.0
PYH2_k127_2151596_3 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307,K14387 - - 0.0000000000000000000000000000000000000000000000000113 197.0
PYH2_k127_2151596_4 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000000000000000001505 193.0
PYH2_k127_2151596_6 sequence-specific DNA binding K18830 - - 0.0000000000000000000000000000000000003887 143.0
PYH2_k127_2151596_8 Membrane - - - 0.000000000000000000000007372 110.0
PYH2_k127_2151596_9 - - - - 0.000000000000000000008197 98.0
PYH2_k127_2156058_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 304.0
PYH2_k127_2156058_1 PFAM molybdopterin oxidoreductase Fe4S4 region - - - 0.0000000000000000000000000000000000000000000000000001774 188.0
PYH2_k127_2156058_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.000000000000000000000000000001178 123.0
PYH2_k127_2187669_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002081 286.0
PYH2_k127_2227667_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.574e-195 619.0
PYH2_k127_2227667_1 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002933 550.0
PYH2_k127_2227667_10 ABC-type tungstate transport system, periplasmic component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002587 252.0
PYH2_k127_2227667_11 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000001122 245.0
PYH2_k127_2227667_12 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000001292 253.0
PYH2_k127_2227667_14 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000007986 159.0
PYH2_k127_2227667_15 TetR family transcriptional regulator - - - 0.000000000000000000000000003711 119.0
PYH2_k127_2227667_16 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000001465 108.0
PYH2_k127_2227667_17 - - - - 0.000000000000000000009675 93.0
PYH2_k127_2227667_18 Preprotein translocase SecG subunit K03075 - - 0.000000000000000006533 87.0
PYH2_k127_2227667_19 membrane - - - 0.0000000001837 65.0
PYH2_k127_2227667_2 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 371.0
PYH2_k127_2227667_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003425 351.0
PYH2_k127_2227667_4 ATPase activity K02010,K02017,K02019,K02049,K02068,K02071,K06857,K10112 - 3.6.3.29,3.6.3.30,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 350.0
PYH2_k127_2227667_5 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
PYH2_k127_2227667_6 UbiA prenyltransferase family K02548 - 2.5.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 309.0
PYH2_k127_2227667_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000225 290.0
PYH2_k127_2227667_8 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003608 273.0
PYH2_k127_2227667_9 PBP superfamily domain K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005768 263.0
PYH2_k127_2249627_0 NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007645 458.0
PYH2_k127_2249627_1 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000002429 214.0
PYH2_k127_2249627_2 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000001692 193.0
PYH2_k127_2249627_3 Transcriptional regulator, Crp Fnr family K10914,K21563 - - 0.000000000000000000000000000000000000000000000001707 181.0
PYH2_k127_2249627_4 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000101 167.0
PYH2_k127_2257946_0 Radical SAM N-terminal - - - 4.715e-274 852.0
PYH2_k127_2257946_1 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 7.066e-257 801.0
PYH2_k127_2257946_10 regulatory protein, FmdB family - - - 0.0000000000000000188 84.0
PYH2_k127_2257946_11 Regulatory protein, FmdB family - - - 0.00000009682 56.0
PYH2_k127_2257946_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 617.0
PYH2_k127_2257946_3 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006588 282.0
PYH2_k127_2257946_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002704 253.0
PYH2_k127_2257946_5 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000005546 229.0
PYH2_k127_2257946_6 PFAM cobalamin B12-binding domain protein K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000008709 192.0
PYH2_k127_2257946_7 Putative zinc- or iron-chelating domain K06940 - - 0.0000000000000000000000000000003966 128.0
PYH2_k127_2257946_8 PFAM Nitroreductase - - - 0.000000000000000000000000007143 117.0
PYH2_k127_2257946_9 dolichyl monophosphate biosynthetic process K08591 - 2.3.1.15 0.0000000000000000001466 96.0
PYH2_k127_2269232_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K00196 - - 0.000000000000000000000000000000000000000000000005194 176.0
PYH2_k127_2269232_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000001148 168.0
PYH2_k127_2302635_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.269e-245 768.0
PYH2_k127_2302635_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 460.0
PYH2_k127_2302635_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
PYH2_k127_2302635_3 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 308.0
PYH2_k127_2302635_4 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000001212 147.0
PYH2_k127_2302635_5 - - - - 0.0000000000000006298 81.0
PYH2_k127_2337862_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.07e-269 839.0
PYH2_k127_2337862_1 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 1.586e-236 742.0
PYH2_k127_2337862_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 4.186e-194 612.0
PYH2_k127_2337862_3 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004309 361.0
PYH2_k127_2337862_4 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003187 289.0
PYH2_k127_2337862_5 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000006713 188.0
PYH2_k127_2337862_6 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000003643 162.0
PYH2_k127_2337862_7 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000000000007499 132.0
PYH2_k127_2366457_0 cell adhesion involved in biofilm formation - - - 0.000000000000000000000000004335 127.0
PYH2_k127_2388985_0 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009694 324.0
PYH2_k127_2388985_1 YtkA-like - - - 0.00000001633 57.0
PYH2_k127_2430525_0 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 397.0
PYH2_k127_2430525_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 358.0
PYH2_k127_2430525_10 Universal stress protein family - - - 0.00000000000000000795 89.0
PYH2_k127_2430525_11 Protein of unknown function (DUF664) - - - 0.0000000000000001263 86.0
PYH2_k127_2430525_2 SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 312.0
PYH2_k127_2430525_3 Malate/L-lactate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008076 281.0
PYH2_k127_2430525_4 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001688 261.0
PYH2_k127_2430525_5 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.00000000000000000000000000000000000000000000000000000000001458 217.0
PYH2_k127_2430525_6 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.00000000000000000000000000000000000000000000000000000002335 208.0
PYH2_k127_2430525_7 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000007406 211.0
PYH2_k127_2430525_8 PFAM transglutaminase domain protein - - - 0.0000000000000000000000000000000000000000000000000001375 208.0
PYH2_k127_2430525_9 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.000000000000000000000006676 104.0
PYH2_k127_2438849_0 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.0000000000000000000000000000000000003349 153.0
PYH2_k127_2438849_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000294 104.0
PYH2_k127_247155_0 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002354 283.0
PYH2_k127_247155_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003523 246.0
PYH2_k127_247155_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000007291 213.0
PYH2_k127_247155_3 AIR synthase related protein, C-terminal domain - - - 0.00001629 48.0
PYH2_k127_2506091_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 495.0
PYH2_k127_2512420_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000001156 88.0
PYH2_k127_2543323_0 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000002769 224.0
PYH2_k127_2546795_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007781 324.0
PYH2_k127_2546795_1 Beta-lactamase K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000456 231.0
PYH2_k127_258536_0 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000004613 229.0
PYH2_k127_258536_1 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000269 198.0
PYH2_k127_258536_2 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K11177 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000002843 201.0
PYH2_k127_258536_3 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000001087 192.0
PYH2_k127_258536_4 FHA domain protein - - - 0.00005146 53.0
PYH2_k127_2593907_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 3.324e-194 653.0
PYH2_k127_2659385_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 6.602e-262 811.0
PYH2_k127_2659385_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000001222 72.0
PYH2_k127_2661757_0 PFAM AMP-dependent synthetase and ligase K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000003102 226.0
PYH2_k127_2661757_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000001032 198.0
PYH2_k127_2661757_2 Family of unknown function (DUF5343) - - - 0.0000000000000000000003947 101.0
PYH2_k127_2673156_0 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000003503 166.0
PYH2_k127_26865_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 503.0
PYH2_k127_2690181_1 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000003051 55.0
PYH2_k127_271020_0 Involved in initiation control of chromosome replication - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 416.0
PYH2_k127_2723820_0 Winged helix-turn helix - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000364 395.0
PYH2_k127_2723820_1 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.000000000005273 68.0
PYH2_k127_2760629_0 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 365.0
PYH2_k127_2760629_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000001141 172.0
PYH2_k127_2760629_2 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000006207 95.0
PYH2_k127_277057_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 436.0
PYH2_k127_277057_1 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 429.0
PYH2_k127_277057_2 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 407.0
PYH2_k127_277057_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738,K19515 - 1.2.7.5 0.00000000000000000000000000000000000000000003773 168.0
PYH2_k127_2830790_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 591.0
PYH2_k127_2832092_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 505.0
PYH2_k127_2832092_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000008549 114.0
PYH2_k127_2836739_0 Group II intron, maturase-specific domain K00986,K15342 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005527 467.0
PYH2_k127_2846849_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000951 173.0
PYH2_k127_2846849_1 Protein of unknown function (DUF4256) - - - 0.00000000000000000000000000000000000000004999 151.0
PYH2_k127_2846849_2 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000009448 51.0
PYH2_k127_2848997_0 AAA-like domain K06915 - - 6.579e-226 712.0
PYH2_k127_2848997_1 Carboxylesterase family K03929 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004775 455.0
PYH2_k127_2848997_10 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000001348 187.0
PYH2_k127_2848997_2 NurA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 328.0
PYH2_k127_2848997_3 Poly A polymerase head domain K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 308.0
PYH2_k127_2848997_4 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 297.0
PYH2_k127_2848997_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000004751 270.0
PYH2_k127_2848997_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006577 257.0
PYH2_k127_2848997_7 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004938 245.0
PYH2_k127_2848997_8 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000005023 244.0
PYH2_k127_2848997_9 PFAM HAS barrel domain - - - 0.0000000000000000000000000000000000000000000000000001972 191.0
PYH2_k127_2853660_0 Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 344.0
PYH2_k127_2853660_1 XFP N-terminal domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003502 342.0
PYH2_k127_2853660_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003187 310.0
PYH2_k127_2853660_3 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001324 294.0
PYH2_k127_2853660_4 PFAM GDSL-like Lipase Acylhydrolase - - - 0.0000000000000000000000000000000000000000000000000006387 190.0
PYH2_k127_2853660_5 sh3 domain protein - - - 0.000000000000000000000000000000000000000000000000000718 202.0
PYH2_k127_2853660_6 Protein of unknown function (DUF2851) - - - 0.00000000000000000000000000000000000000000001819 178.0
PYH2_k127_2853660_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000001248 132.0
PYH2_k127_2853660_8 - - - - 0.0002003 45.0
PYH2_k127_2854678_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 316.0
PYH2_k127_2854678_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006431 279.0
PYH2_k127_2854678_2 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000008281 257.0
PYH2_k127_2854678_3 CoA-transferase family III - - - 0.000000000000000000000000000000004873 132.0
PYH2_k127_2869129_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 493.0
PYH2_k127_2869129_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 449.0
PYH2_k127_2869129_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000007279 155.0
PYH2_k127_2869129_11 Thioesterase superfamily K02614 - - 0.00000000000000000000000000000000002068 139.0
PYH2_k127_2869129_12 Transcription factor zinc-finger K09981 - - 0.000000000000000000000000000001824 124.0
PYH2_k127_2869129_13 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000003427 127.0
PYH2_k127_2869129_14 META domain - - - 0.00000000002955 70.0
PYH2_k127_2869129_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 377.0
PYH2_k127_2869129_3 Protein of unknown function (DUF933) K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 377.0
PYH2_k127_2869129_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 342.0
PYH2_k127_2869129_5 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 314.0
PYH2_k127_2869129_6 Bacterial transferase hexapeptide (six repeats) K00640 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009001,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016407,GO:0016412,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019344,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 289.0
PYH2_k127_2869129_7 PFAM ApbE family K09740 - - 0.000000000000000000000000000000000000000000000000000000000000000000003899 242.0
PYH2_k127_2869129_8 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000001856 232.0
PYH2_k127_2869129_9 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH2_k127_2899639_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.624e-313 970.0
PYH2_k127_2899639_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 9.962e-296 934.0
PYH2_k127_2899639_10 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 441.0
PYH2_k127_2899639_11 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 395.0
PYH2_k127_2899639_12 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 371.0
PYH2_k127_2899639_13 Iron-containing alcohol dehydrogenase K00001,K04072 - 1.1.1.1,1.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 365.0
PYH2_k127_2899639_14 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 328.0
PYH2_k127_2899639_15 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005931 317.0
PYH2_k127_2899639_16 PFAM LmbE family protein K18455 - 3.5.1.115 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 313.0
PYH2_k127_2899639_17 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 307.0
PYH2_k127_2899639_18 TIGRFAM ROK family protein K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001881 280.0
PYH2_k127_2899639_19 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004978 267.0
PYH2_k127_2899639_2 Domain of unknown function (DUF3536) - - - 9.569e-267 843.0
PYH2_k127_2899639_20 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000001145 259.0
PYH2_k127_2899639_21 efflux protein, MATE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001597 267.0
PYH2_k127_2899639_22 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000001523 211.0
PYH2_k127_2899639_23 ACT domain - - - 0.00000000000000000000000000000000000000000000000000002806 192.0
PYH2_k127_2899639_24 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000127 179.0
PYH2_k127_2899639_25 Sterol carrier protein domain - - - 0.0000000000000000000000000000000000000000000007495 181.0
PYH2_k127_2899639_26 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000003844 144.0
PYH2_k127_2899639_27 PFAM Methylated-DNA- protein -cysteine K07443 - - 0.000000000000000000000000001151 115.0
PYH2_k127_2899639_28 Sugar (and other) transporter - - - 0.000000000000000000000005599 115.0
PYH2_k127_2899639_29 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.00000000000005313 75.0
PYH2_k127_2899639_3 Carbohydrate phosphorylase K00688 - 2.4.1.1 5.355e-243 769.0
PYH2_k127_2899639_31 - - - - 0.000001319 59.0
PYH2_k127_2899639_4 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.825e-233 746.0
PYH2_k127_2899639_5 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 582.0
PYH2_k127_2899639_6 PFAM glycoside hydrolase family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 581.0
PYH2_k127_2899639_7 peptidase dimerisation domain protein K01436 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 471.0
PYH2_k127_2899639_8 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 452.0
PYH2_k127_2899639_9 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 442.0
PYH2_k127_2940939_0 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000004512 235.0
PYH2_k127_2940939_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000004003 93.0
PYH2_k127_2940939_2 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000002916 71.0
PYH2_k127_295045_0 multicopper oxidases K06324 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016679,GO:0016682,GO:0016722,GO:0052716,GO:0055114 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 410.0
PYH2_k127_2965273_0 Ig-like domain from next to BRCA1 gene - - - 0.000000000000000000000000000000000006128 152.0
PYH2_k127_2965273_1 ubiquitin binding - GO:0000407,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005776,GO:0006914,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016236,GO:0032182,GO:0043130,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0061919 - 0.00001434 57.0
PYH2_k127_297869_0 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000000000000000000000000000000000000000000002215 260.0
PYH2_k127_297869_1 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000002952 246.0
PYH2_k127_297869_2 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000001046 246.0
PYH2_k127_297869_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000001579 211.0
PYH2_k127_297869_4 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000003988 179.0
PYH2_k127_297869_5 - - - - 0.000000000000000000000000000000000001657 147.0
PYH2_k127_2994549_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 5e-324 1002.0
PYH2_k127_2994549_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.232e-320 1003.0
PYH2_k127_2994549_10 Phosphoglycerate kinase K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 456.0
PYH2_k127_2994549_11 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 390.0
PYH2_k127_2994549_12 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 297.0
PYH2_k127_2994549_13 Two component transcriptional regulator, winged helix family K07669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003231 282.0
PYH2_k127_2994549_14 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004911 280.0
PYH2_k127_2994549_15 Alkyl sulfatase dimerisation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004713 256.0
PYH2_k127_2994549_16 histidine kinase, HAMP K07642 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000001294 241.0
PYH2_k127_2994549_17 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000003408 235.0
PYH2_k127_2994549_18 lipoprotein transporter activity K02003,K05685 - - 0.000000000000000000000000000000000000000000000000000000000000002913 224.0
PYH2_k127_2994549_19 methyltransferase K00641 - 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000002829 214.0
PYH2_k127_2994549_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 6.667e-242 762.0
PYH2_k127_2994549_20 Putative small multi-drug export protein - - - 0.0000000000000000000000000000000000000000000001277 175.0
PYH2_k127_2994549_21 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000003714 143.0
PYH2_k127_2994549_23 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.000000000000000000000000000004527 121.0
PYH2_k127_2994549_24 spore germination K03605 - - 0.000000000000000000000000000006469 125.0
PYH2_k127_2994549_25 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000001352 118.0
PYH2_k127_2994549_26 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000001129 93.0
PYH2_k127_2994549_27 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.0000000000000004077 78.0
PYH2_k127_2994549_28 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000001561 65.0
PYH2_k127_2994549_29 ABC transporter substrate-binding protein K02035 - - 0.0000002995 57.0
PYH2_k127_2994549_3 PFAM Cys Met metabolism pyridoxal-phosphate-dependent protein K01740 - 2.5.1.49 4.437e-211 664.0
PYH2_k127_2994549_30 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000003772 53.0
PYH2_k127_2994549_31 PFAM Integrase catalytic region K07497 - - 0.00007062 45.0
PYH2_k127_2994549_32 Ftsk_gamma K03466 - - 0.0001368 47.0
PYH2_k127_2994549_33 Domain of unknown function (DUF4190) - - - 0.0008535 47.0
PYH2_k127_2994549_4 Pyridoxal-phosphate dependent enzyme K01697 - 4.2.1.22 1.131e-202 640.0
PYH2_k127_2994549_5 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 602.0
PYH2_k127_2994549_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 544.0
PYH2_k127_2994549_7 Cys/Met metabolism PLP-dependent enzyme K01739,K01758 - 2.5.1.48,4.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004681 534.0
PYH2_k127_2994549_8 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 509.0
PYH2_k127_2994549_9 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 499.0
PYH2_k127_3010853_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 554.0
PYH2_k127_3010853_1 Serine aminopeptidase, S33 K01048 GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 0.00000000000000000000000000000000000000000000000000000001176 208.0
PYH2_k127_3011264_0 Ferrous iron transport protein B K04759 - - 1.181e-244 771.0
PYH2_k127_3011264_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 353.0
PYH2_k127_3011264_10 Rhodanese Homology Domain - - - 0.000000000000000000000000000000003941 133.0
PYH2_k127_3011264_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000001335 111.0
PYH2_k127_3011264_12 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K00657,K00663,K19278,K19301 - 2.3.1.57,2.3.1.82 0.0000000000000002557 84.0
PYH2_k127_3011264_13 Protein of unknown function (DUF664) - - - 0.00000000000002057 80.0
PYH2_k127_3011264_15 Siderophore biosynthesis protein domain K00663 - 2.3.1.82 0.0000002538 57.0
PYH2_k127_3011264_2 DeoC/LacD family aldolase K01635 - 4.1.2.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 338.0
PYH2_k127_3011264_3 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 305.0
PYH2_k127_3011264_4 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 290.0
PYH2_k127_3011264_5 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 292.0
PYH2_k127_3011264_6 Electron transfer flavoprotein domain K03522,K22432 - 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000001668 245.0
PYH2_k127_3011264_7 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.00000000000000000000000000000000000000000000000000000000000000001142 253.0
PYH2_k127_3011264_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000003049 193.0
PYH2_k127_3011264_9 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.00000000000000000000000000000000004578 145.0
PYH2_k127_3016756_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000001334 156.0
PYH2_k127_3016756_1 Multicopper oxidase K06324 - 1.16.3.3 0.000000000000000000000000000000000001232 147.0
PYH2_k127_3024491_0 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000006613 104.0
PYH2_k127_3065589_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 338.0
PYH2_k127_3065589_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 303.0
PYH2_k127_3065589_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000005961 226.0
PYH2_k127_3065589_3 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000011 192.0
PYH2_k127_3065589_4 thiolester hydrolase activity K06889 - - 0.0000000000000000000000000000000000000000000000001079 184.0
PYH2_k127_3065589_5 Transcriptional regulator - - - 0.0000000000000000000000000000113 127.0
PYH2_k127_3065589_6 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0004362 43.0
PYH2_k127_3083254_0 Integrase catalytic region K07497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 338.0
PYH2_k127_3083254_1 Transposase K00957,K07497 - 2.7.7.4 0.0000000000000001424 90.0
PYH2_k127_3083254_2 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.000000002705 58.0
PYH2_k127_3083254_3 transposase activity K07483 - - 0.00000002365 59.0
PYH2_k127_3088960_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 381.0
PYH2_k127_3088960_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 313.0
PYH2_k127_3088960_2 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000281 269.0
PYH2_k127_3107762_0 Protein of unknown function, DUF255 K06888 - - 4.382e-232 737.0
PYH2_k127_3107762_1 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000284 66.0
PYH2_k127_3108834_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335,K15022,K18331 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0044237,GO:0044424,GO:0044464,GO:0045333,GO:0055114,GO:0071944 1.12.1.3,1.17.1.10,1.6.5.3 3.134e-314 993.0
PYH2_k127_3108834_1 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 1.967e-210 666.0
PYH2_k127_3108834_2 Molybdopterin oxidoreductase Fe4S4 region K00336,K05299 - 1.17.1.10,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 364.0
PYH2_k127_3108834_3 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 321.0
PYH2_k127_3108834_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000004659 217.0
PYH2_k127_3108834_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000007444 175.0
PYH2_k127_3108834_6 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003137 168.0
PYH2_k127_3108834_7 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000001503 126.0
PYH2_k127_3119234_0 Nitroreductase family - - - 0.000000000000000000000000000000001771 140.0
PYH2_k127_3119234_1 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000005806 122.0
PYH2_k127_3144873_0 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000002422 215.0
PYH2_k127_3144873_1 PFAM GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000000001762 176.0
PYH2_k127_3144873_2 PAAR repeat-containing protein - - - 0.0000000000000000000000000000000000000002128 151.0
PYH2_k127_3208402_0 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005637 576.0
PYH2_k127_3208402_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 554.0
PYH2_k127_3208402_10 3'-5' exonuclease activity K03547 - - 0.0000000000000000000000000000000542 134.0
PYH2_k127_3208402_11 Cobalamin synthesis protein cobW C-terminal domain - - - 0.000000000000000000000000000003734 125.0
PYH2_k127_3208402_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000385 462.0
PYH2_k127_3208402_3 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 337.0
PYH2_k127_3208402_4 MFS_1 like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 309.0
PYH2_k127_3208402_5 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000522 264.0
PYH2_k127_3208402_6 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001098 251.0
PYH2_k127_3208402_7 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000000000000000000000000000000000000000000000000000000000008442 244.0
PYH2_k127_3208402_8 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000001609 245.0
PYH2_k127_3208402_9 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000916 236.0
PYH2_k127_3209005_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 9.552e-304 939.0
PYH2_k127_3209005_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 4.808e-291 906.0
PYH2_k127_3209005_10 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000004154 171.0
PYH2_k127_3209005_11 Flavodoxin-like fold - - - 0.00000000000000000000000000000000000000188 151.0
PYH2_k127_3209005_12 Thioredoxin K03671 - - 0.000000000000000000000000000000000006351 139.0
PYH2_k127_3209005_13 - - - - 0.00000007591 57.0
PYH2_k127_3209005_2 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 4.039e-224 702.0
PYH2_k127_3209005_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002289 419.0
PYH2_k127_3209005_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 411.0
PYH2_k127_3209005_5 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 295.0
PYH2_k127_3209005_6 regulation of RNA biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 285.0
PYH2_k127_3209005_7 AAA domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009377 282.0
PYH2_k127_3209005_8 Protein of unknown function (DUF2167) - - - 0.00000000000000000000000000000000000000000000000000000003879 206.0
PYH2_k127_3209005_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000004613 184.0
PYH2_k127_3231826_0 conserved repeat domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 342.0
PYH2_k127_3231826_1 sequence-specific DNA binding - - - 0.0000000000000000000004183 97.0
PYH2_k127_3231826_2 sequence-specific DNA binding K18830 - - 0.000000000000006837 76.0
PYH2_k127_3231826_3 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 GO:0001539,GO:0005575,GO:0005576,GO:0005623,GO:0006928,GO:0008150,GO:0009288,GO:0009420,GO:0009421,GO:0009987,GO:0040011,GO:0042995,GO:0043226,GO:0043228,GO:0044422,GO:0044461,GO:0044463,GO:0044464,GO:0048870,GO:0051179,GO:0051674,GO:0071973,GO:0097588 - 0.000000000001081 79.0
PYH2_k127_3231826_4 - - - - 0.000000276 54.0
PYH2_k127_3240891_0 carboxylic ester hydrolase activity K03929 - - 0.000000000000000000000000000000000000000000000006248 177.0
PYH2_k127_3240891_1 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.0000000000000000000000001147 114.0
PYH2_k127_3253081_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 349.0
PYH2_k127_3253081_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 331.0
PYH2_k127_3253081_2 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000002133 233.0
PYH2_k127_3253081_3 3-oxoacid CoA-transferase, B subunit K01029 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000005778 211.0
PYH2_k127_3253081_4 coenzyme A transferase K01031 - 2.8.3.6 0.000000000000000000000000000000000000001666 157.0
PYH2_k127_3253081_5 PFAM regulatory protein TetR - - - 0.000000000000000000000000000001068 129.0
PYH2_k127_3253081_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000001733 117.0
PYH2_k127_3253081_7 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000009857 105.0
PYH2_k127_3253081_8 PFAM CoA-transferase family III - - - 0.0002543 44.0
PYH2_k127_327033_0 Anthranilate synthase component I, N terminal region K01657,K01665,K13950 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 488.0
PYH2_k127_327033_1 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008299 442.0
PYH2_k127_327033_2 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009112 354.0
PYH2_k127_327033_3 Pterin binding enzyme K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 318.0
PYH2_k127_327033_4 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 314.0
PYH2_k127_327033_5 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000005519 257.0
PYH2_k127_327033_6 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000001242 223.0
PYH2_k127_327033_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000001896 214.0
PYH2_k127_3282236_0 Histidine kinase - - - 0.0000000000000000000000002193 116.0
PYH2_k127_3282236_1 Pfam:N_methyl_2 K02650 - - 0.000000000000001657 81.0
PYH2_k127_3282236_2 PFAM multicopper oxidase type 2 - - - 0.00000000000001055 76.0
PYH2_k127_3285627_0 domain protein K13735,K15125,K20276 - - 0.00001024 58.0
PYH2_k127_3286259_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 555.0
PYH2_k127_3286259_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 334.0
PYH2_k127_3286259_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009536 312.0
PYH2_k127_3286259_3 conserved protein (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003547 317.0
PYH2_k127_3286259_4 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000004709 188.0
PYH2_k127_3286259_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000007145 111.0
PYH2_k127_3286259_6 Domain of unknown function (DUF1893) - - - 0.0000000000004235 76.0
PYH2_k127_331866_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000003699 201.0
PYH2_k127_331866_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000002233 101.0
PYH2_k127_3425796_0 RadC-like JAB domain K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005304 282.0
PYH2_k127_3425796_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000000000000000000000003743 136.0
PYH2_k127_3425796_2 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.00007494 46.0
PYH2_k127_3437322_0 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000001964 206.0
PYH2_k127_3437322_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000002964 105.0
PYH2_k127_3437322_2 R3H domain - - - 0.00000000000000000002984 92.0
PYH2_k127_344567_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 7.675e-280 882.0
PYH2_k127_344567_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 316.0
PYH2_k127_344567_2 Belongs to the peptidase M50B family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 316.0
PYH2_k127_344567_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006905 274.0
PYH2_k127_344567_4 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006657 252.0
PYH2_k127_344567_5 COG0243 Anaerobic dehydrogenases, typically selenocysteine-containing K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000001964 201.0
PYH2_k127_344567_6 Amino acid permease - - - 0.0000000000000000000000000003042 120.0
PYH2_k127_344567_7 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000009103 85.0
PYH2_k127_34558_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 373.0
PYH2_k127_34558_1 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 314.0
PYH2_k127_34558_2 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002702 276.0
PYH2_k127_34558_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000001583 175.0
PYH2_k127_34558_4 FCD domain protein - - - 0.000000000000000000000000000001924 129.0
PYH2_k127_3475446_0 Carboxyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005242 400.0
PYH2_k127_3475446_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001524 291.0
PYH2_k127_3475446_2 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001795 272.0
PYH2_k127_3475446_3 COG4799 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) - - - 0.000000000000000000000000000000000000000000000000000000008648 206.0
PYH2_k127_3476652_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 349.0
PYH2_k127_3476652_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008875 244.0
PYH2_k127_3476652_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 0.0000000000000000000000000000000000000002709 152.0
PYH2_k127_3476652_3 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000000000002573 136.0
PYH2_k127_3505401_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 417.0
PYH2_k127_3505401_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003019 266.0
PYH2_k127_3505401_2 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000002912 189.0
PYH2_k127_3537344_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 4.53e-199 640.0
PYH2_k127_3537344_1 Phage integrase family K04763 - - 0.000000000000000000000000000000000000000000271 172.0
PYH2_k127_3583322_0 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 586.0
PYH2_k127_3583322_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002333 507.0
PYH2_k127_3583322_2 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 443.0
PYH2_k127_3583322_3 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 310.0
PYH2_k127_3583322_4 PFAM CoA-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000004678 231.0
PYH2_k127_3583322_5 PBS lyase HEAT-like repeat - - - 0.00000000000000000000000000000000000000000000000000004762 199.0
PYH2_k127_3583322_6 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000001284 174.0
PYH2_k127_3583322_7 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000001407 79.0
PYH2_k127_360355_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001712 252.0
PYH2_k127_360355_1 HD domain - - - 0.00000000001197 68.0
PYH2_k127_360355_2 PFAM PfkB K00856 - 2.7.1.20 0.000001164 51.0
PYH2_k127_372624_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 607.0
PYH2_k127_372624_1 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009741 523.0
PYH2_k127_372624_10 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 383.0
PYH2_k127_372624_11 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 361.0
PYH2_k127_372624_12 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003878 353.0
PYH2_k127_372624_13 PFAM thiamine pyrophosphate enzyme K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 351.0
PYH2_k127_372624_14 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007609 324.0
PYH2_k127_372624_15 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH2_k127_372624_16 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003217 267.0
PYH2_k127_372624_17 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002118 265.0
PYH2_k127_372624_18 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH2_k127_372624_19 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000007438 241.0
PYH2_k127_372624_2 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 513.0
PYH2_k127_372624_20 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000575 217.0
PYH2_k127_372624_21 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000004232 211.0
PYH2_k127_372624_22 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000008276 210.0
PYH2_k127_372624_23 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000007082 177.0
PYH2_k127_372624_24 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000755 170.0
PYH2_k127_372624_25 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000001005 148.0
PYH2_k127_372624_26 PFAM NUDIX hydrolase - - - 0.00000000000000000000000000000000000002598 148.0
PYH2_k127_372624_27 Tyrosine phosphatase family K01104 - 3.1.3.48 0.00000000000000000000000000000000001161 146.0
PYH2_k127_372624_28 oxidoreductase, delta subunit K00171 - 1.2.7.1 0.000000000000000000000000000000266 124.0
PYH2_k127_372624_29 PFAM 4Fe-4S binding domain K00338 - 1.6.5.3 0.0000000009862 64.0
PYH2_k127_372624_3 ferredoxin oxidoreductase alpha subunit K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 429.0
PYH2_k127_372624_30 - - - - 0.00000000344 65.0
PYH2_k127_372624_4 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002344 422.0
PYH2_k127_372624_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 406.0
PYH2_k127_372624_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 407.0
PYH2_k127_372624_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 396.0
PYH2_k127_372624_8 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 394.0
PYH2_k127_372624_9 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 379.0
PYH2_k127_3734024_0 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000006554 258.0
PYH2_k127_3734024_1 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.000000000000000000000000005278 112.0
PYH2_k127_3734024_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000007448 98.0
PYH2_k127_3734024_3 translation release factor activity - - - 0.000000000002057 76.0
PYH2_k127_374291_0 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 513.0
PYH2_k127_374291_1 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 314.0
PYH2_k127_374291_2 Class II aldolase K01628 - 4.1.2.17 0.0000000002273 69.0
PYH2_k127_3743828_0 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
PYH2_k127_3743828_1 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000000000000000000000000000000000001471 178.0
PYH2_k127_3757614_0 succinate dehydrogenase K00394 - 1.8.99.2 1.678e-286 893.0
PYH2_k127_3757614_1 chelatase, subunit ChlI K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 538.0
PYH2_k127_3757614_2 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000008376 256.0
PYH2_k127_3757614_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000000000000000000004056 222.0
PYH2_k127_3757614_4 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000006442 185.0
PYH2_k127_3757614_5 Protein of unknown function (DUF541) K09807 - - 0.000000000000000000000000000000000000000000000000005347 189.0
PYH2_k127_3757614_7 Glyoxalase-like domain K05606 - 5.1.99.1 0.000000000125 68.0
PYH2_k127_3768922_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006083 603.0
PYH2_k127_3768922_1 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002292 518.0
PYH2_k127_3768922_10 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001404 253.0
PYH2_k127_3768922_11 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000001311 238.0
PYH2_k127_3768922_12 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000004182 235.0
PYH2_k127_3768922_13 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000001959 166.0
PYH2_k127_3768922_14 PHP domain K07053 - 3.1.3.97 0.0000000000000000000000000000000000000001868 160.0
PYH2_k127_3768922_15 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000189 149.0
PYH2_k127_3768922_16 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000001059 136.0
PYH2_k127_3768922_17 AAA domain K07028 - - 0.00000000000392 75.0
PYH2_k127_3768922_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 516.0
PYH2_k127_3768922_3 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007938 458.0
PYH2_k127_3768922_4 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 434.0
PYH2_k127_3768922_5 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 374.0
PYH2_k127_3768922_6 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 372.0
PYH2_k127_3768922_7 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007239 339.0
PYH2_k127_3768922_8 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009576 313.0
PYH2_k127_3768922_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000004303 264.0
PYH2_k127_3782148_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 379.0
PYH2_k127_3782148_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000001502 227.0
PYH2_k127_3782148_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.000000000000000000000000000000002791 132.0
PYH2_k127_3825126_0 Acyl-CoA dehydrogenase, N-terminal K00248,K18244 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000004789 189.0
PYH2_k127_3825126_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01908 - 6.2.1.17 0.00000000000000000000000000000000000000000000000002218 182.0
PYH2_k127_3832806_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 8.968e-295 922.0
PYH2_k127_3832806_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004383 526.0
PYH2_k127_3832806_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 512.0
PYH2_k127_3832806_3 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 419.0
PYH2_k127_3832806_4 cobalamin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000001188 250.0
PYH2_k127_3832806_5 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000000000001223 121.0
PYH2_k127_3832806_6 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000003319 61.0
PYH2_k127_3840509_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 5.122e-218 691.0
PYH2_k127_3840509_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 586.0
PYH2_k127_3840509_10 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000001289 174.0
PYH2_k127_3840509_11 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000002974 159.0
PYH2_k127_3840509_12 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00000000000000000000000000000000000000004212 159.0
PYH2_k127_3840509_13 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000008199 141.0
PYH2_k127_3840509_14 - - - - 0.000000000000000000000000000002536 121.0
PYH2_k127_3840509_15 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000007462 117.0
PYH2_k127_3840509_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000007593 119.0
PYH2_k127_3840509_17 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000001161 115.0
PYH2_k127_3840509_18 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000001808 70.0
PYH2_k127_3840509_19 - - - - 0.0000000006732 61.0
PYH2_k127_3840509_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002727 525.0
PYH2_k127_3840509_20 - - - - 0.00000001572 58.0
PYH2_k127_3840509_3 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 308.0
PYH2_k127_3840509_4 GTP cyclohydrolase I activity K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 292.0
PYH2_k127_3840509_5 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004941 275.0
PYH2_k127_3840509_6 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000002264 229.0
PYH2_k127_3840509_7 competence protein - - - 0.000000000000000000000000000000000000000000000000000000000004942 215.0
PYH2_k127_3840509_8 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000004894 222.0
PYH2_k127_3840509_9 Bifunctional coenzyme A synthase K02318 GO:0000003,GO:0001667,GO:0002009,GO:0002064,GO:0002065,GO:0002066,GO:0002165,GO:0003006,GO:0003674,GO:0003824,GO:0004140,GO:0004595,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005759,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006928,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007297,GO:0007300,GO:0007303,GO:0007444,GO:0007472,GO:0007476,GO:0007552,GO:0007560,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009653,GO:0009791,GO:0009886,GO:0009887,GO:0009888,GO:0009987,GO:0010631,GO:0015936,GO:0015937,GO:0016020,GO:0016301,GO:0016310,GO:0016477,GO:0016482,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019867,GO:0019953,GO:0022412,GO:0022414,GO:0030154,GO:0030707,GO:0030855,GO:0031090,GO:0031966,GO:0031967,GO:0031968,GO:0031974,GO:0031975,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035107,GO:0035114,GO:0035120,GO:0035220,GO:0035239,GO:0035295,GO:0040011,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0046390,GO:0046483,GO:0046907,GO:0048468,GO:0048477,GO:0048513,GO:0048563,GO:0048569,GO:0048609,GO:0048707,GO:0048729,GO:0048731,GO:0048736,GO:0048737,GO:0048856,GO:0048869,GO:0048870,GO:0048878,GO:0051179,GO:0051186,GO:0051188,GO:0051234,GO:0051641,GO:0051649,GO:0051674,GO:0051704,GO:0055086,GO:0055088,GO:0055090,GO:0060429,GO:0060562,GO:0065007,GO:0065008,GO:0070013,GO:0070328,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090130,GO:0090132,GO:0090407,GO:0098588,GO:0098805,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24,2.7.7.3 0.0000000000000000000000000000000000000000000004224 173.0
PYH2_k127_3855403_0 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 334.0
PYH2_k127_3855403_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 320.0
PYH2_k127_3855403_10 - - - - 0.0000000000000000000000000002375 125.0
PYH2_k127_3855403_11 PFAM glutaredoxin - - - 0.00000000000000000000000001748 113.0
PYH2_k127_3855403_12 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000002366 109.0
PYH2_k127_3855403_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000005713 230.0
PYH2_k127_3855403_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000002609 214.0
PYH2_k127_3855403_4 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000002426 214.0
PYH2_k127_3855403_5 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000003627 179.0
PYH2_k127_3855403_6 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000001967 182.0
PYH2_k127_3855403_7 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000002823 148.0
PYH2_k127_3855403_8 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000002596 133.0
PYH2_k127_3855403_9 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000009643 120.0
PYH2_k127_3862852_0 Transketolase, pyrimidine binding domain K21417 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001877 273.0
PYH2_k127_3862852_1 histone deacetylase K04768 - - 0.0000000000000000000000000000000000000000000000000001655 199.0
PYH2_k127_3862852_2 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00627,K00658 - 2.3.1.12,2.3.1.61 0.0000000000000000000000000000000000000000000000000003746 194.0
PYH2_k127_3862852_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000005874 187.0
PYH2_k127_3862852_4 KR domain K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.0000000000000000000000000000000000001366 151.0
PYH2_k127_3862852_5 Conserved hypothetical protein (Lin0512_fam) - - - 0.00000000000000000000003422 102.0
PYH2_k127_3862852_6 Alcohol dehydrogenase GroES domain protein K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000005198 100.0
PYH2_k127_3862852_7 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000006646 60.0
PYH2_k127_3870361_0 Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 594.0
PYH2_k127_3870361_1 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 560.0
PYH2_k127_3870361_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.000000000000000000000000000000000000000000000000000001978 201.0
PYH2_k127_3870361_3 AMP binding - - - 0.0000000000000000000000000000000000000000000000003719 187.0
PYH2_k127_3870361_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000002092 109.0
PYH2_k127_3879606_0 COG2015, Alkyl sulfatase and related hydrolases K01138 - - 1.681e-200 639.0
PYH2_k127_3879606_1 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000001547 202.0
PYH2_k127_3881309_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.384e-233 737.0
PYH2_k127_3881309_1 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004918 275.0
PYH2_k127_3881309_2 Electron transfer flavoprotein K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000004943 262.0
PYH2_k127_3881309_3 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000002062 180.0
PYH2_k127_3891707_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483 - 1.14.14.9 6.392e-206 650.0
PYH2_k127_3891707_1 Alpha/beta hydrolase family K22318 - - 0.00000000000000000000000000000000000000000000000000000000000000000007148 241.0
PYH2_k127_3891707_2 Esterase PHB depolymerase - - - 0.00000000000000000000000000000000000000000000000000000005585 208.0
PYH2_k127_3891707_3 Metallo-beta-lactamase superfamily K05555 - - 0.00000000000000000000000005751 117.0
PYH2_k127_3891707_4 PFAM regulatory protein TetR - - - 0.00000000001683 72.0
PYH2_k127_3891707_5 4-hydroxyphenylacetate K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.0003215 45.0
PYH2_k127_3932421_0 Transposase - - - 0.000000000000000000000000000000000000000000001065 169.0
PYH2_k127_3932421_1 Transposase DDE domain - - - 0.000000000000000000000000000000275 132.0
PYH2_k127_3951455_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 449.0
PYH2_k127_3951455_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 370.0
PYH2_k127_3951455_2 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 320.0
PYH2_k127_3951455_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000001421 87.0
PYH2_k127_3951455_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000152 82.0
PYH2_k127_4009517_0 carboxylic ester hydrolase activity K15357 - 3.5.1.106 0.0000000000000000000000000000000000000000000000000000000001229 204.0
PYH2_k127_4009517_1 Transposase - - - 0.000000000000000000000000000001577 125.0
PYH2_k127_4042614_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 1.094e-305 947.0
PYH2_k127_4042614_1 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 520.0
PYH2_k127_4042614_10 MarC family integral membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000004265 193.0
PYH2_k127_4042614_11 Ecdysteroid kinase - - - 0.0000000000000000000000000000000000000000000000000006413 198.0
PYH2_k127_4042614_12 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000002518 185.0
PYH2_k127_4042614_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004462 169.0
PYH2_k127_4042614_14 acetyltransferase K18815 - 2.3.1.82 0.000000000000000000000000000000000000007661 151.0
PYH2_k127_4042614_2 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 480.0
PYH2_k127_4042614_3 malic enzyme K00027 - 1.1.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 448.0
PYH2_k127_4042614_4 Beta-eliminating lyase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009688 406.0
PYH2_k127_4042614_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 383.0
PYH2_k127_4042614_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 372.0
PYH2_k127_4042614_7 Peptidase dimerisation domain K01438 - 3.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 372.0
PYH2_k127_4042614_8 MFS_1 like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 341.0
PYH2_k127_4042614_9 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004316 259.0
PYH2_k127_4045218_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006689 289.0
PYH2_k127_4045218_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000003984 255.0
PYH2_k127_4064642_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000006563 182.0
PYH2_k127_4065356_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 499.0
PYH2_k127_4065356_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 448.0
PYH2_k127_4065356_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000004329 183.0
PYH2_k127_4065356_3 ethyl tert-butyl ether degradation - - - 0.0000000000000000000008514 98.0
PYH2_k127_4065356_4 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000133 102.0
PYH2_k127_4117262_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000005934 204.0
PYH2_k127_4117262_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000001143 152.0
PYH2_k127_4130150_0 beta-lactamase - - - 1.348e-207 651.0
PYH2_k127_4130150_1 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.00000005386 58.0
PYH2_k127_413488_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 290.0
PYH2_k127_413488_1 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007336 284.0
PYH2_k127_413488_2 COG1680 Beta-lactamase class C and other penicillin binding proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009254 273.0
PYH2_k127_413488_3 Chloramphenicol phosphotransferase-like protein K18554 - - 0.00000000000000000000000000000000000000000002228 168.0
PYH2_k127_413488_4 Dehydrogenase K00004 - 1.1.1.303,1.1.1.4 0.00000000000000004641 85.0
PYH2_k127_4137340_0 Group II intron, maturase-specific domain K00986,K15342 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 551.0
PYH2_k127_4137340_1 4Fe-4S dicluster domain - - - 0.0000000000000000002202 87.0
PYH2_k127_4183008_0 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 287.0
PYH2_k127_4183008_1 Beta-lactamase class C - - - 0.000000000000000000000000000000000000000000000000000000000000000003218 242.0
PYH2_k127_4183008_2 Rhomboid family - - - 0.00000000000000000000000000000000000000000001063 169.0
PYH2_k127_4183008_3 Lrp/AsnC ligand binding domain - - - 0.00000000000000003544 83.0
PYH2_k127_4233386_0 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000021 184.0
PYH2_k127_4233386_1 PFAM Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000002573 156.0
PYH2_k127_4276153_0 COG0657 Esterase lipase - - - 0.000000000000000000000000000000000000000000000000000000000000311 219.0
PYH2_k127_4276153_1 Putative Fe-S cluster - - - 0.00000000000000000000000002867 114.0
PYH2_k127_4276153_2 Protein of unknown function (DUF1461) - - - 0.000000000000000000000001718 112.0
PYH2_k127_4358383_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 382.0
PYH2_k127_4358383_1 nitrate reductase activity - - - 0.000000000000000000000000000000000009865 144.0
PYH2_k127_4358383_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000000000548 136.0
PYH2_k127_4358383_3 Transcriptional regulator, arsR family - - - 0.00000000000000000000002689 103.0
PYH2_k127_4358383_4 - - - - 0.00000000000000000000002722 104.0
PYH2_k127_4358383_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000001597 78.0
PYH2_k127_4360941_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004788 398.0
PYH2_k127_4360941_1 phosphatidylinositol metabolic process K13671 - - 0.0000000000000000000000000000000000000000000000004501 193.0
PYH2_k127_4360941_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000005639 155.0
PYH2_k127_4360941_3 X-Pro dipeptidyl-peptidase (S15 family) K06889,K07397 - - 0.00000000000000000000000142 112.0
PYH2_k127_4371429_0 Peptide ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001268 276.0
PYH2_k127_4371429_1 Flavodoxin - - - 0.00000000000000000000000000000008247 131.0
PYH2_k127_4371429_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000003914 131.0
PYH2_k127_4371429_3 histidine kinase, dimerisation and phosphoacceptor region - - - 0.0000000003464 63.0
PYH2_k127_4371429_4 Two component regulator propeller - - - 0.00000004085 55.0
PYH2_k127_4371429_5 Histidine kinase K11617 - 2.7.13.3 0.0000001568 54.0
PYH2_k127_4391650_0 Baseplate J-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 530.0
PYH2_k127_4391650_1 PFAM GPW gp25 family protein K06903 - - 0.000000000000000000000000000000000000000000000001762 176.0
PYH2_k127_4391650_2 PFAM Phage tail protein (Tail_P2_I) - - - 0.00000000000000000000000001681 115.0
PYH2_k127_4391650_3 PAAR motif - - - 0.000000003182 58.0
PYH2_k127_4416219_0 Transposase - - - 0.000000000000000000000000002106 124.0
PYH2_k127_4423936_0 An AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase, an enzyme that catalyzes the formation of malonyl-CoA, which in turn controls the rate of fatty acid metabolism K01961 - 6.3.4.14,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 478.0
PYH2_k127_4423936_1 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 389.0
PYH2_k127_4423936_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000269 69.0
PYH2_k127_4423936_11 Cyclic nucleotide-monophosphate binding domain - - - 0.0000004448 58.0
PYH2_k127_4423936_12 LacY proton/sugar symporter - - - 0.00007549 48.0
PYH2_k127_4423936_13 helix_turn_helix, Lux Regulon - - - 0.0001021 52.0
PYH2_k127_4423936_2 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002828 264.0
PYH2_k127_4423936_3 helix_turn_helix, Lux Regulon K11618 - - 0.00000000000000000000000000000000000000000000000000000000000001726 222.0
PYH2_k127_4423936_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000007797 217.0
PYH2_k127_4423936_5 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000001691 201.0
PYH2_k127_4423936_6 Protein of unknown function (DUF402) K09145 - - 0.000000000000000000000000000000000000165 149.0
PYH2_k127_4423936_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000539 94.0
PYH2_k127_4423936_8 methyl-accepting chemotaxis protein K03406 - - 0.0000000000000001791 94.0
PYH2_k127_4423936_9 Integrase core domain - - - 0.00000000002812 64.0
PYH2_k127_4452146_0 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 390.0
PYH2_k127_4452146_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001057 278.0
PYH2_k127_4452146_2 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.00000000000001863 74.0
PYH2_k127_446264_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001917 226.0
PYH2_k127_4484329_0 Transposase DDE domain group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 477.0
PYH2_k127_4484329_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000004501 263.0
PYH2_k127_4505699_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000001279 101.0
PYH2_k127_4505699_1 Transcriptional regulator - - - 0.00000000000000000006359 96.0
PYH2_k127_4510101_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 307.0
PYH2_k127_4510101_1 PFAM glycosyl transferase family 2 K14597 - - 0.000000000000000000000000000000000000000000000000000000000000000000001224 251.0
PYH2_k127_4510101_10 - K01385 - 3.4.23.42 0.0001907 54.0
PYH2_k127_4510101_2 Carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000003206 192.0
PYH2_k127_4510101_3 Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000604 177.0
PYH2_k127_4510101_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000004025 121.0
PYH2_k127_4510101_5 Protein of unknown function (DUF3343) - - - 0.0000000000000000000002989 101.0
PYH2_k127_4510101_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.00000000000000002313 89.0
PYH2_k127_4510101_7 - K07112 - - 0.00000003182 65.0
PYH2_k127_4510101_8 PFAM Flavodoxin K03809 - 1.6.5.2 0.0000008717 57.0
PYH2_k127_4510101_9 Protein of unknown function (DUF3343) - - - 0.000002467 50.0
PYH2_k127_4521997_0 Integrase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007616 324.0
PYH2_k127_4521997_1 Pfam Transposase K07483 - - 0.00000000000000000000000000000000000002911 145.0
PYH2_k127_465984_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003811 466.0
PYH2_k127_465984_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 337.0
PYH2_k127_465984_2 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 331.0
PYH2_k127_465984_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005703 270.0
PYH2_k127_465984_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000001853 216.0
PYH2_k127_465984_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000001229 206.0
PYH2_k127_465984_6 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0000000000000001841 86.0
PYH2_k127_465984_7 - - - - 0.000000004261 65.0
PYH2_k127_468773_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 362.0
PYH2_k127_468773_1 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007135 282.0
PYH2_k127_468773_2 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000009868 240.0
PYH2_k127_468773_3 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000004162 229.0
PYH2_k127_468773_4 - - - - 0.0000000000000000008805 96.0
PYH2_k127_468773_5 peroxiredoxin activity K03386 - 1.11.1.15 0.000000000000001708 76.0
PYH2_k127_468773_6 Domain of unknown function (DUF362) - - - 0.00000000001582 67.0
PYH2_k127_468773_7 Domain of unknown function (DUF362) - - - 0.0006171 45.0
PYH2_k127_4691084_0 Probable zinc-ribbon domain - - - 0.00000000000001017 76.0
PYH2_k127_4694393_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 578.0
PYH2_k127_4694393_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 479.0
PYH2_k127_4694393_2 PFAM Translin K07477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003352 248.0
PYH2_k127_4694393_3 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000004719 242.0
PYH2_k127_4694393_4 PFAM Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000003259 226.0
PYH2_k127_4694393_5 Amino acid permease - - - 0.0000000000000000000000000000000000002838 146.0
PYH2_k127_4738256_0 Zinc-uptake complex component A periplasmic K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000001609 233.0
PYH2_k127_4738256_1 COG1121 ABC-type Mn Zn transport systems, ATPase component K09817 - - 0.00000000000001563 77.0
PYH2_k127_4746625_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 460.0
PYH2_k127_4746625_1 methylmalonyl-CoA K01849 - 5.4.99.2 0.000000000000000000007518 97.0
PYH2_k127_475049_0 Transposase IS4 family protein - - - 0.000000000000000000001788 104.0
PYH2_k127_475861_0 - - - - 0.00000001239 68.0
PYH2_k127_4763350_0 bacterial-type flagellum-dependent cell motility - - - 0.000000000002319 78.0
PYH2_k127_4826101_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.391e-203 644.0
PYH2_k127_4826101_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 1.073e-202 640.0
PYH2_k127_4826101_10 Sigma-70 region 2 K03088 - - 0.00000000000000000000000000000000000000000000000000002633 194.0
PYH2_k127_4826101_11 FR47-like protein K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000008344 168.0
PYH2_k127_4826101_12 endonuclease containing a URI domain K07461 - - 0.000000000000000000000000000000000004632 140.0
PYH2_k127_4826101_13 TPM domain K06872 - - 0.000000000000000000000000000000000027 147.0
PYH2_k127_4826101_14 - - - - 0.0000000000000000000000000000007873 126.0
PYH2_k127_4826101_15 GH3 auxin-responsive promoter - - - 0.000000000000000000000003152 116.0
PYH2_k127_4826101_16 - - - - 0.00000000000000000000005159 110.0
PYH2_k127_4826101_17 Preprotein translocase subunit K03210 - - 0.0000000000000000001755 93.0
PYH2_k127_4826101_18 Putative zinc ribbon domain - - - 0.000000000000000009071 86.0
PYH2_k127_4826101_19 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.00000000000000001238 84.0
PYH2_k127_4826101_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 438.0
PYH2_k127_4826101_20 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000002752 74.0
PYH2_k127_4826101_21 - - - - 0.0000000000001234 73.0
PYH2_k127_4826101_22 Altronate hydrolase K01685 GO:0003674,GO:0003824,GO:0005975,GO:0005996,GO:0006063,GO:0006082,GO:0008150,GO:0008152,GO:0008789,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019586,GO:0019698,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046365,GO:0046395,GO:0046396,GO:0046397,GO:0071704,GO:0072329,GO:1901575 4.2.1.7 0.0000000000003813 75.0
PYH2_k127_4826101_3 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 418.0
PYH2_k127_4826101_4 D-galactarate dehydratase / Altronate hydrolase, C terminus K16850 - 4.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 394.0
PYH2_k127_4826101_5 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 314.0
PYH2_k127_4826101_6 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 310.0
PYH2_k127_4826101_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000177 223.0
PYH2_k127_4826101_8 HIT domain K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000001643 213.0
PYH2_k127_4826101_9 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000002353 196.0
PYH2_k127_4835449_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1146.0
PYH2_k127_4835449_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 409.0
PYH2_k127_4835449_10 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003231 258.0
PYH2_k127_4835449_11 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000009215 237.0
PYH2_k127_4835449_12 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000512 235.0
PYH2_k127_4835449_13 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000002263 176.0
PYH2_k127_4835449_14 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000000001862 151.0
PYH2_k127_4835449_15 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000002956 149.0
PYH2_k127_4835449_16 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000001846 110.0
PYH2_k127_4835449_17 FR47-like protein - - - 0.000000000000000000218 95.0
PYH2_k127_4835449_18 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000001179 81.0
PYH2_k127_4835449_2 enoyl-(acyl-carrier-protein) reductase II K02371 - 1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 379.0
PYH2_k127_4835449_20 DSBA-like thioredoxin domain - - - 0.000001098 57.0
PYH2_k127_4835449_21 Serine aminopeptidase, S33 - - - 0.000002807 51.0
PYH2_k127_4835449_3 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 354.0
PYH2_k127_4835449_4 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006883 338.0
PYH2_k127_4835449_5 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 332.0
PYH2_k127_4835449_6 PFAM short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000284 287.0
PYH2_k127_4835449_7 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002047 281.0
PYH2_k127_4835449_8 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001696 267.0
PYH2_k127_4835449_9 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002571 269.0
PYH2_k127_4840737_0 Fatty acid desaturase K10255 - 1.14.19.23,1.14.19.45 0.0000000000000000000000000000000001285 133.0
PYH2_k127_4840737_1 alpha/beta hydrolase fold - - - 0.000776 48.0
PYH2_k127_4849512_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 501.0
PYH2_k127_4849512_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003566 493.0
PYH2_k127_4849512_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000002595 113.0
PYH2_k127_4849512_3 Family of unknown function (DUF5343) - - - 0.0000000000000000000518 94.0
PYH2_k127_4849512_4 - - - - 0.00008558 47.0
PYH2_k127_4849699_0 Transposase IS66 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 328.0
PYH2_k127_4881182_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 2.002e-249 787.0
PYH2_k127_4881182_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.39e-228 721.0
PYH2_k127_4881182_10 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 265.0
PYH2_k127_4881182_11 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000335 261.0
PYH2_k127_4881182_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 245.0
PYH2_k127_4881182_13 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000005845 205.0
PYH2_k127_4881182_14 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000002106 179.0
PYH2_k127_4881182_15 PFAM heat shock protein DnaJ domain protein K05516 - - 0.0000000000000000000000000000000000000000006042 167.0
PYH2_k127_4881182_16 - - - - 0.000000000000000000000000000000000000000008148 161.0
PYH2_k127_4881182_17 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000002161 117.0
PYH2_k127_4881182_18 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000002181 109.0
PYH2_k127_4881182_19 Phospholipid methyltransferase - - - 0.0000000000000000000000004553 111.0
PYH2_k127_4881182_2 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 7.927e-218 687.0
PYH2_k127_4881182_20 Protein of unknown function (DUF448) K07742 - - 0.0000000000000000001928 91.0
PYH2_k127_4881182_21 Transcription factor zinc-finger K09981 - - 0.000000000007236 75.0
PYH2_k127_4881182_22 - - - - 0.00000002522 59.0
PYH2_k127_4881182_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 514.0
PYH2_k127_4881182_4 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009481 507.0
PYH2_k127_4881182_5 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000731 481.0
PYH2_k127_4881182_6 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 464.0
PYH2_k127_4881182_7 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005142 428.0
PYH2_k127_4881182_8 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 428.0
PYH2_k127_4881182_9 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001204 342.0
PYH2_k127_4887466_0 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 428.0
PYH2_k127_4887466_1 Belongs to the enoyl-CoA hydratase isomerase family K01715,K13766 - 4.2.1.17,4.2.1.18 0.00000000000000000000000000000000000000000002767 171.0
PYH2_k127_4887466_2 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000003729 138.0
PYH2_k127_4887466_3 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.00000000000000007842 80.0
PYH2_k127_4887466_4 Catalyzes the oxidation of L-aspartate to iminoaspartate K00239 - 1.3.5.1,1.3.5.4 0.000000000000003285 78.0
PYH2_k127_488943_0 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 602.0
PYH2_k127_488943_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 596.0
PYH2_k127_488943_2 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 401.0
PYH2_k127_488943_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 312.0
PYH2_k127_488943_4 Cation efflux family K16264 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004955 248.0
PYH2_k127_488943_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000009477 228.0
PYH2_k127_488943_6 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000002106 190.0
PYH2_k127_4895838_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1730.0
PYH2_k127_4895838_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1311.0
PYH2_k127_4895838_10 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000001508 215.0
PYH2_k127_4895838_11 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.00000000000000000000000000000000000000000000000000001645 195.0
PYH2_k127_4895838_12 Dihydroxyacetone kinase family - - - 0.0000000000000000000000000000000000000000001384 170.0
PYH2_k127_4895838_13 phosphoribosyl-AMP cyclohydrolase activity K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000002232 145.0
PYH2_k127_4895838_14 Chromatin associated protein KTI12 - - - 0.000000000000000000000000000000000006005 144.0
PYH2_k127_4895838_15 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000001222 139.0
PYH2_k127_4895838_16 heat shock protein DnaJ domain protein K03686,K05516 - - 0.0000000000000000000000000000002497 131.0
PYH2_k127_4895838_17 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000004013 89.0
PYH2_k127_4895838_18 Dihydroxyacetone kinase family - - - 0.000000000004491 70.0
PYH2_k127_4895838_19 - - - - 0.00000002409 61.0
PYH2_k127_4895838_2 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 8.607e-204 651.0
PYH2_k127_4895838_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 490.0
PYH2_k127_4895838_4 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 370.0
PYH2_k127_4895838_5 IMP dehydrogenase / GMP reductase domain K00459,K02371 - 1.13.12.16,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 361.0
PYH2_k127_4895838_6 Aldo/keto reductase family K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 357.0
PYH2_k127_4895838_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 328.0
PYH2_k127_4895838_8 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 239.0
PYH2_k127_4895838_9 ATP-grasp domain K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000103 234.0
PYH2_k127_4910074_0 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 349.0
PYH2_k127_4910074_1 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004519 289.0
PYH2_k127_4910074_2 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001122 276.0
PYH2_k127_4910074_3 Belongs to the 'phage' integrase family K04763 - - 0.0000000000000000000000000000000000001083 156.0
PYH2_k127_4910074_4 Belongs to the 'phage' integrase family K04763 - - 0.00008333 51.0
PYH2_k127_4910074_5 - - - - 0.0003641 43.0
PYH2_k127_491143_0 Two component transcriptional regulator, LuxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002858 278.0
PYH2_k127_491143_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000006887 237.0
PYH2_k127_491143_2 - - - - 0.0001452 49.0
PYH2_k127_4914184_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 443.0
PYH2_k127_4914184_1 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 381.0
PYH2_k127_4914184_10 phosphoesterase, PA-phosphatase related - - - 0.00000000000000000000000000002774 125.0
PYH2_k127_4914184_11 - - - - 0.00009437 51.0
PYH2_k127_4914184_12 electron transfer flavoprotein, alpha subunit K03522 - - 0.0006972 44.0
PYH2_k127_4914184_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 345.0
PYH2_k127_4914184_3 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 314.0
PYH2_k127_4914184_4 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 301.0
PYH2_k127_4914184_5 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 308.0
PYH2_k127_4914184_6 electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000874 265.0
PYH2_k127_4914184_7 Hydrogenase accessory protein HypB K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 258.0
PYH2_k127_4914184_8 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000007913 258.0
PYH2_k127_4914184_9 Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000001758 218.0
PYH2_k127_4938197_0 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000328 269.0
PYH2_k127_4954618_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002013 451.0
PYH2_k127_4962091_0 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 342.0
PYH2_k127_4962091_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000004071 199.0
PYH2_k127_4962091_2 - - - - 0.0000000000000000000022 96.0
PYH2_k127_4962091_3 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.0000000000001519 71.0
PYH2_k127_4963499_0 - - - - 0.00000000000000000000000000000008008 136.0
PYH2_k127_4963499_1 - - - - 0.000000009261 61.0
PYH2_k127_4971172_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 564.0
PYH2_k127_4971172_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 512.0
PYH2_k127_4971172_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 380.0
PYH2_k127_4971172_3 Catalyzes the NAD( )-dependent oxidative deamination of L-alanine to pyruvate, and the reverse reaction, the reductive amination of pyruvate K01750,K19244 - 1.4.1.1,4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009064 377.0
PYH2_k127_4971172_4 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 325.0
PYH2_k127_4971172_5 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000007573 226.0
PYH2_k127_4971172_6 AcrB/AcrD/AcrF family K03296 - - 0.00000000000000000000000000000000000000000000000000000002702 203.0
PYH2_k127_4971172_7 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000002027 179.0
PYH2_k127_4971172_8 - - - - 0.0000000000000000000000000000000000001648 144.0
PYH2_k127_4971172_9 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000004338 96.0
PYH2_k127_500661_0 C-terminal, D2-small domain, of ClpB protein K03696 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0008150,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030312,GO:0040007,GO:0042802,GO:0042803,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046983,GO:0071944 - 0.0 1069.0
PYH2_k127_500661_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 451.0
PYH2_k127_500661_10 zinc finger - - - 0.00000000000000005624 90.0
PYH2_k127_500661_11 Unextendable partial coding region - - - 0.000000000000001192 80.0
PYH2_k127_500661_12 PFAM Biotin lipoyl attachment - - - 0.0000000000000474 75.0
PYH2_k127_500661_13 - - - - 0.0000000000002911 72.0
PYH2_k127_500661_14 COG NOG38524 non supervised orthologous group - - - 0.000000000006527 69.0
PYH2_k127_500661_15 - - - - 0.00000000002823 68.0
PYH2_k127_500661_16 Helix-turn-helix domain - - - 0.00000000003117 66.0
PYH2_k127_500661_17 COG NOG15344 non supervised orthologous group - - - 0.00000000004734 63.0
PYH2_k127_500661_19 - - - - 0.00009202 45.0
PYH2_k127_500661_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000003233 216.0
PYH2_k127_500661_3 Catalyzes the reversible hydration of unsaturated fatty acyl-CoA to beta-hydroxyacyl-CoA - - - 0.000000000000000000000000000000000000000000000000000000006484 208.0
PYH2_k127_500661_4 Protein of unknown function (DUF664) - - - 0.000000000000000000000000000000000003287 144.0
PYH2_k127_500661_5 twitching motility protein K02669 - - 0.00000000000000000000000000000001751 130.0
PYH2_k127_500661_6 - - - - 0.000000000000000000000000000002957 119.0
PYH2_k127_500661_7 GYD domain - - - 0.0000000000000000000000000009612 115.0
PYH2_k127_500661_8 - - - - 0.00000000000000000000007406 98.0
PYH2_k127_500661_9 COG NOG15344 non supervised orthologous group - - - 0.0000000000000000000008676 95.0
PYH2_k127_500846_0 bacterial-type flagellum-dependent cell motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 313.0
PYH2_k127_500846_1 C-terminal domain of CHU protein family - - - 0.000000000000000000000000000000000001195 160.0
PYH2_k127_5032698_0 protein possibly involved in aromatic compounds catabolism - - - 0.0000000000000000000000000000000000000000000000003482 179.0
PYH2_k127_5032698_1 PFAM Plasmid maintenance system killer K07334 - - 0.000000000000000000000000000000000000002346 149.0
PYH2_k127_5032698_2 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.0002294 44.0
PYH2_k127_5038222_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 467.0
PYH2_k127_5038222_1 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.00000000000000000000000001893 111.0
PYH2_k127_5045509_0 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000192 268.0
PYH2_k127_5045509_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000003655 141.0
PYH2_k127_5060942_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 402.0
PYH2_k127_5060942_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 395.0
PYH2_k127_5060942_2 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000006742 174.0
PYH2_k127_5082276_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001122 249.0
PYH2_k127_5082276_1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000001019 207.0
PYH2_k127_5082276_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000001288 177.0
PYH2_k127_5082276_4 KR domain - - - 0.00000000000000000000000000000001689 137.0
PYH2_k127_5082276_5 TAP-like protein - - - 0.0000000000000000000000000001442 125.0
PYH2_k127_5082276_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000006671 86.0
PYH2_k127_5095178_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1405.0
PYH2_k127_5095178_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 557.0
PYH2_k127_5095178_10 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000735 235.0
PYH2_k127_5095178_11 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002306 229.0
PYH2_k127_5095178_12 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000001663 241.0
PYH2_k127_5095178_13 basic membrane K07335 - - 0.00000000000000000000000000000000000000000000000000000000000004911 227.0
PYH2_k127_5095178_14 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000000001676 209.0
PYH2_k127_5095178_15 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000001257 205.0
PYH2_k127_5095178_16 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000001448 222.0
PYH2_k127_5095178_17 NifU-like N terminal domain K04488 - - 0.00000000000000000000000000000000000000000000000000008513 188.0
PYH2_k127_5095178_18 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.00000000000000000000000000000001887 136.0
PYH2_k127_5095178_19 -acetyltransferase - - - 0.0000000000000000000000000001005 120.0
PYH2_k127_5095178_2 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 467.0
PYH2_k127_5095178_20 sulfur carrier activity - - - 0.0000000000000000000000001272 107.0
PYH2_k127_5095178_21 positive regulation of macromolecule biosynthetic process K03973 - - 0.000000000000000000004425 103.0
PYH2_k127_5095178_22 - - - - 0.000000000000000001937 89.0
PYH2_k127_5095178_23 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.0000000006938 64.0
PYH2_k127_5095178_24 Flavodoxin domain - - - 0.00000001867 63.0
PYH2_k127_5095178_25 SNARE associated Golgi protein - - - 0.00001286 48.0
PYH2_k127_5095178_26 Protein of unknown function (DUF998) - - - 0.000267 51.0
PYH2_k127_5095178_3 Carboxylesterase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 445.0
PYH2_k127_5095178_4 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 415.0
PYH2_k127_5095178_5 MmgE/PrpD family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 400.0
PYH2_k127_5095178_6 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000002488 267.0
PYH2_k127_5095178_7 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
PYH2_k127_5095178_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000276 251.0
PYH2_k127_5095178_9 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000005487 259.0
PYH2_k127_5110308_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 1.088e-226 715.0
PYH2_k127_5110308_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 542.0
PYH2_k127_5110308_2 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002921 378.0
PYH2_k127_5110308_3 Protein of unknown function (DUF2889) K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000396 164.0
PYH2_k127_5110308_4 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000001416 77.0
PYH2_k127_5110308_5 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.0000006241 59.0
PYH2_k127_5116094_0 ACT domain K00928 - 2.7.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 538.0
PYH2_k127_5116094_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 426.0
PYH2_k127_5116094_2 Metalloenzyme superfamily K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006039 273.0
PYH2_k127_5116094_3 TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000004677 229.0
PYH2_k127_5124711_0 binding-protein-dependent transport systems inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005373 274.0
PYH2_k127_5124711_1 ABC-type sugar transport system, permease component K02026 - - 0.00000000000000000007335 93.0
PYH2_k127_5124711_2 ABC-type sugar transport system periplasmic component K02027 - - 0.000002909 51.0
PYH2_k127_5241688_0 Catalyzes the reversible NADPH-dependent reductive amination of L-2-amino-6-oxopimelate, the acyclic form of L- tetrahydrodipicolinate, to generate the meso compound, D,L-2,6- diaminopimelate K03340 - 1.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 374.0
PYH2_k127_5241688_1 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000007674 247.0
PYH2_k127_5241688_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000111 232.0
PYH2_k127_5241688_3 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000000189 147.0
PYH2_k127_5241688_4 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K11329 - - 0.0000000000000000000001362 101.0
PYH2_k127_5241688_5 - - - - 0.000007097 54.0
PYH2_k127_5287306_0 Creatinine amidohydrolase K01470,K22232 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003375 282.0
PYH2_k127_5287306_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000257 221.0
PYH2_k127_5291419_0 Belongs to the peptidase S16 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 321.0
PYH2_k127_5291419_1 Type IV leader peptidase family K02654 - 3.4.23.43 0.0000000000000000000000000001775 118.0
PYH2_k127_5319970_0 Transposase IS66 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 308.0
PYH2_k127_5347606_0 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001325 284.0
PYH2_k127_5347606_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000002132 245.0
PYH2_k127_5347606_2 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003295 243.0
PYH2_k127_5347606_3 GrpB protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000003311 238.0
PYH2_k127_5347606_4 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001332 236.0
PYH2_k127_5347606_5 KR domain K07124 - - 0.000000000000000000000000000000000000000000000000000001133 203.0
PYH2_k127_5347606_6 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000005113 113.0
PYH2_k127_5347606_7 DsrE/DsrF-like family K04085 - - 0.00000000000000000000000001255 112.0
PYH2_k127_5347606_8 Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000003228 108.0
PYH2_k127_5355019_0 - - - - 0.000000000006624 79.0
PYH2_k127_5355019_1 Ribbon-helix-helix protein, copG family - - - 0.000000000011 67.0
PYH2_k127_5355019_2 PIN domain - - - 0.00000001613 60.0
PYH2_k127_5355019_3 - - - - 0.00001865 53.0
PYH2_k127_5359650_0 CARDB - - - 0.000004871 58.0
PYH2_k127_540413_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 301.0
PYH2_k127_540413_1 Protein of unknown function (DUF664) - - - 0.0000000000000000000000000000000001884 138.0
PYH2_k127_54631_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000009559 208.0
PYH2_k127_54631_1 Glutamine amidotransferase domain K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000002706 194.0
PYH2_k127_54631_2 DNA photolyase K01669 - 4.1.99.3 0.000000000000000000000000000000000000000004512 155.0
PYH2_k127_54631_3 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00004389 46.0
PYH2_k127_54778_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 9.07e-219 683.0
PYH2_k127_54778_1 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 466.0
PYH2_k127_54778_10 Sucrose-6F-phosphate phosphohydrolase - - - 0.00000000000000000000000000000005091 136.0
PYH2_k127_54778_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000002066 82.0
PYH2_k127_54778_12 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000000001191 70.0
PYH2_k127_54778_2 3-Oxoacyl- acyl-carrier-protein (ACP) synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 427.0
PYH2_k127_54778_3 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 363.0
PYH2_k127_54778_4 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 332.0
PYH2_k127_54778_5 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002119 268.0
PYH2_k127_54778_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000003807 236.0
PYH2_k127_54778_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000003917 205.0
PYH2_k127_54778_8 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000000000001893 179.0
PYH2_k127_54778_9 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000005498 130.0
PYH2_k127_5500047_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005261 444.0
PYH2_k127_5500047_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 361.0
PYH2_k127_5500047_2 - - - - 0.000000000000000000000000000000000000000000000000000002694 205.0
PYH2_k127_5500047_4 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000003182 164.0
PYH2_k127_5500047_5 Thioredoxin-like - - - 0.000000000000000000000000005799 127.0
PYH2_k127_5506483_0 COG0477 Permeases of the major facilitator superfamily K08177 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003006 488.0
PYH2_k127_5506483_1 Methyltransferase type 11 - - - 0.0000000000000004046 78.0
PYH2_k127_5546266_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986,K15342 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 485.0
PYH2_k127_5661310_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.181e-218 686.0
PYH2_k127_5661310_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 409.0
PYH2_k127_5661310_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000001064 188.0
PYH2_k127_566602_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007183 290.0
PYH2_k127_566602_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000001331 241.0
PYH2_k127_566602_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000006119 235.0
PYH2_k127_566602_3 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000007391 239.0
PYH2_k127_566602_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000002458 206.0
PYH2_k127_566602_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000002003 199.0
PYH2_k127_566602_6 PFAM Vitamin B12 dependent methionine synthase, activation domain - - - 0.00000000000000000000000000000000000000000000000005075 187.0
PYH2_k127_566602_7 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000008138 171.0
PYH2_k127_5693292_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1087.0
PYH2_k127_5693292_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004877 440.0
PYH2_k127_5693292_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006526 373.0
PYH2_k127_5693292_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 357.0
PYH2_k127_5693292_4 cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 296.0
PYH2_k127_5693292_5 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000011 244.0
PYH2_k127_5693292_6 Competence-damaged protein K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000001632 163.0
PYH2_k127_5693292_7 AMP binding - - - 0.000000000000000000000000001028 118.0
PYH2_k127_5693292_8 Regulatory protein, FmdB family - - - 0.000009161 49.0
PYH2_k127_5693420_0 transcriptional regulator - - - 0.00000000001784 75.0
PYH2_k127_5717480_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000004656 201.0
PYH2_k127_5717480_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000226 141.0
PYH2_k127_5728481_0 Elongation factor G C-terminus K06207 - - 1.169e-272 851.0
PYH2_k127_5728481_1 Domain of unknown function (DUF1998) K06877 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005161 587.0
PYH2_k127_5728481_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 414.0
PYH2_k127_5728481_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000003968 244.0
PYH2_k127_5728481_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000000000000000000000000002853 123.0
PYH2_k127_5728481_5 Radical SAM N-terminal - - - 0.000003682 48.0
PYH2_k127_5732765_0 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 392.0
PYH2_k127_5732765_1 Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002106 244.0
PYH2_k127_5732765_2 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000004074 149.0
PYH2_k127_5778206_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 335.0
PYH2_k127_5778206_1 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 314.0
PYH2_k127_5778206_2 Cytochrome c3 - - - 0.0000000000000000000000000000000000000000000000000000000000000491 226.0
PYH2_k127_5778206_3 denitrification pathway - - - 0.00000000000000000000000000000000000000000000001239 180.0
PYH2_k127_5778206_4 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.000000000000000000000000000000000000003874 148.0
PYH2_k127_5778206_5 PFAM Carboxymuconolactone decarboxylase - - - 0.0000000000000000000000000000000000187 137.0
PYH2_k127_5778206_6 Possible catecholamine-binding domain present in a variety of eukaryotic proteins. - - - 0.0000000000000000000000000000000002475 139.0
PYH2_k127_5778206_7 Trm112p-like protein - - - 0.00000000000000001841 83.0
PYH2_k127_5779301_0 - - - - 2.414e-214 680.0
PYH2_k127_5799868_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000001882 229.0
PYH2_k127_5799868_1 sh3 domain protein K01448 - 3.5.1.28 0.0002347 52.0
PYH2_k127_5804829_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 2.269e-282 879.0
PYH2_k127_5804829_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 5.413e-194 618.0
PYH2_k127_5804829_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000001099 168.0
PYH2_k127_5804829_11 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000004969 136.0
PYH2_k127_5804829_12 - - - - 0.0000000000000000000000000000003688 124.0
PYH2_k127_5804829_13 Thioredoxin-like - - - 0.00000000000000000000000009866 113.0
PYH2_k127_5804829_14 - - - - 0.000000000000000000117 88.0
PYH2_k127_5804829_2 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 539.0
PYH2_k127_5804829_3 CO dehydrogenase/acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 502.0
PYH2_k127_5804829_4 Pterin binding enzyme K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 334.0
PYH2_k127_5804829_5 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00123,K00336 - 1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003217 277.0
PYH2_k127_5804829_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001069 279.0
PYH2_k127_5804829_7 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000003869 223.0
PYH2_k127_5804829_8 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001647 201.0
PYH2_k127_5804829_9 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000000001847 181.0
PYH2_k127_5807937_0 response regulator K02479 - - 0.0000000000000000000000000000000000000000000000000000000000000001453 228.0
PYH2_k127_5807937_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001273 216.0
PYH2_k127_5807937_2 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000003256 126.0
PYH2_k127_5837396_0 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 512.0
PYH2_k127_5837396_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002884 261.0
PYH2_k127_5837396_2 Dak1_2 K07030 - - 0.0000000000000000000000000000000001234 134.0
PYH2_k127_5837396_3 Ribosomal L28 family K02902 - - 0.0000000000000000000003197 97.0
PYH2_k127_5841618_0 Belongs to the glycosyl hydrolase 3 family K05349 - 3.2.1.21 0.000000000000000000000000000000000000000000000000000000000000000000306 234.0
PYH2_k127_5841618_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000004033 231.0
PYH2_k127_5841618_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000001514 106.0
PYH2_k127_5846753_0 PFAM Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000543 242.0
PYH2_k127_5846753_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000833 195.0
PYH2_k127_5854063_0 Subtilase family K01342 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 396.0
PYH2_k127_5861455_0 PFAM Sodium sulphate symporter K14445 - - 1.567e-257 801.0
PYH2_k127_5861455_1 NMT1-like family K07080 - - 0.000000000000000001563 89.0
PYH2_k127_5863039_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01908 - 6.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 511.0
PYH2_k127_5905372_0 Belongs to the type-B carboxylesterase lipase family K03929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 396.0
PYH2_k127_5905372_1 Flavodoxin-like fold - - - 0.0000000000000000000000000004044 115.0
PYH2_k127_5914162_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 544.0
PYH2_k127_5914162_1 DHH family K07462 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 539.0
PYH2_k127_5914162_10 Carboxymuconolactone decarboxylase family - - - 0.0000000000000003647 83.0
PYH2_k127_5914162_2 PFAM FAD dependent oxidoreductase K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 412.0
PYH2_k127_5914162_3 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 381.0
PYH2_k127_5914162_4 Dihydrolipoyl dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 362.0
PYH2_k127_5914162_5 phosphoenolpyruvate carboxykinase (ATP) activity K01610 - 4.1.1.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 327.0
PYH2_k127_5914162_6 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002919 288.0
PYH2_k127_5914162_7 acetyl coenzyme A synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004017 287.0
PYH2_k127_5914162_8 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001384 266.0
PYH2_k127_5914162_9 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000001525 171.0
PYH2_k127_5991489_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000002599 225.0
PYH2_k127_5991489_1 MaoC like domain - - - 0.0000000000000000000000000000000000002615 145.0
PYH2_k127_5991489_2 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000001286 103.0
PYH2_k127_6062161_0 ISXO2-like transposase domain K07488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 374.0
PYH2_k127_6088712_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1470.0
PYH2_k127_6088712_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 408.0
PYH2_k127_6088712_2 Domain of unknown function (DUF4162) K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 357.0
PYH2_k127_6088712_3 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002516 276.0
PYH2_k127_6088712_4 Catalyzes the hydrolysis of D-tyrosyl-tRNA(Tyr) K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000003362 138.0
PYH2_k127_6088712_5 toxin-antitoxin pair type II binding - - - 0.000000000000000000000000009198 112.0
PYH2_k127_6088712_6 DUF167 K09131 - - 0.000000000000004477 78.0
PYH2_k127_6102357_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.773e-204 642.0
PYH2_k127_6104230_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 302.0
PYH2_k127_6104230_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000001424 178.0
PYH2_k127_6104230_2 Belongs to the HpcH HpaI aldolase family K01644 GO:0000287,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006107,GO:0008150,GO:0008152,GO:0009987,GO:0019752,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0046872,GO:0071704 4.1.3.34 0.0000000000000000000000000000000000006837 143.0
PYH2_k127_6136356_0 CoA-transferase family III K07544 - 2.8.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001243 289.0
PYH2_k127_6136356_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000181 251.0
PYH2_k127_6136356_2 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000001048 144.0
PYH2_k127_6136356_3 PFAM transglutaminase domain protein - - - 0.00000000000000000000004487 108.0
PYH2_k127_6156185_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 376.0
PYH2_k127_6156185_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005799 330.0
PYH2_k127_6156185_2 Peptide ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000002003 258.0
PYH2_k127_6156185_3 Transposase K07497 - - 0.000000000000000000000000000000000921 131.0
PYH2_k127_6156185_5 activity, protein serine threonine kinase activity, protein-tyrosine kinase activity, ATP binding, regulation of transcription, DNA-dependent, protein amino acid phosphorylation K08282,K13419 - 2.7.11.1 0.0000000001109 67.0
PYH2_k127_6167943_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007349 572.0
PYH2_k127_6167943_1 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 473.0
PYH2_k127_6167943_2 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001205 269.0
PYH2_k127_6167943_3 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000002821 179.0
PYH2_k127_6167943_4 PFAM short-chain dehydrogenase reductase SDR K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000005436 180.0
PYH2_k127_6167943_5 - - - - 0.0000000000000000002662 98.0
PYH2_k127_6167943_6 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000503 70.0
PYH2_k127_61843_0 DegT/DnrJ/EryC1/StrS aminotransferase family K10907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 419.0
PYH2_k127_61843_1 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 316.0
PYH2_k127_6201401_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1215.0
PYH2_k127_6201401_1 R3H domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 587.0
PYH2_k127_6201401_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000005108 111.0
PYH2_k127_6201401_11 60Kd inner membrane protein K03217 - - 0.0000000000000000000000159 102.0
PYH2_k127_6201401_12 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000002863 96.0
PYH2_k127_6201401_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000000004006 94.0
PYH2_k127_6201401_14 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001237 77.0
PYH2_k127_6201401_15 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001036 75.0
PYH2_k127_6201401_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 527.0
PYH2_k127_6201401_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 340.0
PYH2_k127_6201401_4 Tetratricopeptide repeat K12600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003595 259.0
PYH2_k127_6201401_5 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003652 252.0
PYH2_k127_6201401_6 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000001375 195.0
PYH2_k127_6201401_7 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000001827 180.0
PYH2_k127_6201401_8 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000002434 149.0
PYH2_k127_6201401_9 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000000005864 116.0
PYH2_k127_6229291_0 PFAM Transketolase K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 405.0
PYH2_k127_6229291_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 354.0
PYH2_k127_6229291_2 4Fe-4S dicluster domain K08264 - 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 336.0
PYH2_k127_6229291_3 KR domain - - - 0.000000000000000000000000000000000000000000000001339 184.0
PYH2_k127_6229291_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000002716 149.0
PYH2_k127_6229291_5 ATP-NAD kinase - - - 0.00000000002195 65.0
PYH2_k127_6241642_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 7.327e-220 688.0
PYH2_k127_6241642_1 - - - - 0.00000000000000000000000000000000000000000000000000000004165 211.0
PYH2_k127_6241642_3 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000191 164.0
PYH2_k127_6241642_4 Nitrogen regulatory protein P-II K04751 - - 0.000000000000000000000000000000000000004057 148.0
PYH2_k127_6241642_5 amidohydrolase K07045 - - 0.0000000000000000000000000005909 126.0
PYH2_k127_6253339_0 DNA ligase K01971 - 6.5.1.1 4.501e-250 800.0
PYH2_k127_6253339_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 341.0
PYH2_k127_6253339_2 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000005194 193.0
PYH2_k127_6253339_3 Glycosyltransferase family 87 - - - 0.000000000001645 77.0
PYH2_k127_6253339_4 TIGRFAM MATE efflux family protein K03327 - - 0.00002609 49.0
PYH2_k127_6291384_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 430.0
PYH2_k127_6291384_1 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001989 282.0
PYH2_k127_6291384_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000003781 209.0
PYH2_k127_6327572_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 339.0
PYH2_k127_6327572_1 Formyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004604 259.0
PYH2_k127_6327572_2 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000000000007082 217.0
PYH2_k127_6327572_3 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000001313 97.0
PYH2_k127_6402459_0 Secreted repeat of unknown function - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006206 304.0
PYH2_k127_650491_0 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 486.0
PYH2_k127_650491_1 Probable zinc-ribbon domain - - - 0.00000000000006836 74.0
PYH2_k127_6523451_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 384.0
PYH2_k127_6540856_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 586.0
PYH2_k127_654716_0 Domain of unknown function (DUF4418) - - - 0.00000009069 57.0
PYH2_k127_654716_1 Multicopper K06324 - 1.16.3.3 0.0009651 49.0
PYH2_k127_6549705_0 Endopeptidase La K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 583.0
PYH2_k127_6549705_1 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 464.0
PYH2_k127_6549705_10 Binding-protein-dependent transport system inner membrane component K15581 - - 0.000000000000000000000000000000000007806 137.0
PYH2_k127_6549705_11 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000003764 115.0
PYH2_k127_6549705_2 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 436.0
PYH2_k127_6549705_3 N-terminal TM domain of oligopeptide transport permease C K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 428.0
PYH2_k127_6549705_4 VWA containing CoxE family protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 426.0
PYH2_k127_6549705_5 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003896 398.0
PYH2_k127_6549705_6 DNA modification repair radical SAM protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 349.0
PYH2_k127_6549705_7 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005797 320.0
PYH2_k127_6549705_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 300.0
PYH2_k127_6549705_9 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000001917 231.0
PYH2_k127_6553867_0 LacY proton/sugar symporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001792 342.0
PYH2_k127_6553867_1 Major facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000006593 200.0
PYH2_k127_6553867_2 PFAM MerR family regulatory protein - - - 0.000000003511 60.0
PYH2_k127_6601448_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 501.0
PYH2_k127_6601448_1 Aminotransferase class I and II K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 474.0
PYH2_k127_6601448_2 Beta-lactamase class C and other penicillin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 323.0
PYH2_k127_6601448_3 Carboxylesterase family K03929 - - 0.000000000000000000000000000000002672 132.0
PYH2_k127_6636388_0 PFAM Transposase, IS4-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000001458 241.0
PYH2_k127_6638166_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266,K03388 - 1.4.1.13,1.4.1.14,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 530.0
PYH2_k127_6638166_1 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 373.0
PYH2_k127_6638166_10 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.0000000000000000000000000000000000001252 152.0
PYH2_k127_6638166_11 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000003723 139.0
PYH2_k127_6638166_12 Flavodoxin - - - 0.000000000000000000000000000009522 123.0
PYH2_k127_6638166_13 SnoaL-like domain - - - 0.0000000000005985 74.0
PYH2_k127_6638166_14 Bacterial regulatory proteins, tetR family - - - 0.000000000001934 75.0
PYH2_k127_6638166_15 - - - - 0.000000000004048 69.0
PYH2_k127_6638166_16 - - - - 0.000000004675 66.0
PYH2_k127_6638166_17 - - - - 0.00000001574 64.0
PYH2_k127_6638166_18 - - - - 0.00000004055 62.0
PYH2_k127_6638166_19 - - - - 0.000003662 56.0
PYH2_k127_6638166_2 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 338.0
PYH2_k127_6638166_3 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 310.0
PYH2_k127_6638166_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 299.0
PYH2_k127_6638166_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000004199 222.0
PYH2_k127_6638166_6 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000102 196.0
PYH2_k127_6638166_7 Peptide ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000005106 209.0
PYH2_k127_6638166_8 Alcohol dehydrogenase GroES-like domain K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000000000000000002808 198.0
PYH2_k127_6638166_9 - - - - 0.00000000000000000000000000000000000000000003848 170.0
PYH2_k127_6664243_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 6.358e-221 703.0
PYH2_k127_6664243_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 507.0
PYH2_k127_6664243_10 May be involved in the biosynthesis of molybdopterin K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000597 191.0
PYH2_k127_6664243_11 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000002128 181.0
PYH2_k127_6664243_12 Pyruvate kinase, alpha/beta domain K09126 - - 0.000000000000000000000000000000000000000000000003197 179.0
PYH2_k127_6664243_13 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000003076 148.0
PYH2_k127_6664243_14 4Fe-4S dicluster domain K05580 - 1.6.5.3 0.0000000000000000000000000000000005189 136.0
PYH2_k127_6664243_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.00000000000000000000000000000001001 130.0
PYH2_k127_6664243_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000004913 124.0
PYH2_k127_6664243_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004032 492.0
PYH2_k127_6664243_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 465.0
PYH2_k127_6664243_4 MoeA N-terminal region (domain I and II) K03750,K07219 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 441.0
PYH2_k127_6664243_5 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 395.0
PYH2_k127_6664243_6 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 391.0
PYH2_k127_6664243_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 364.0
PYH2_k127_6664243_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 331.0
PYH2_k127_6664243_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003168 237.0
PYH2_k127_6664405_0 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000002512 107.0
PYH2_k127_6664405_1 domain, Protein K01729,K03561,K09942,K12287,K20276 - 4.2.2.3 0.00000000001429 76.0
PYH2_k127_6664405_2 Belongs to the peptidase S8 family K12287 - - 0.00001898 57.0
PYH2_k127_6668795_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 2.84e-200 629.0
PYH2_k127_6668795_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 359.0
PYH2_k127_6668795_10 ThiS family K03636 - - 0.00000006275 57.0
PYH2_k127_6668795_2 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 291.0
PYH2_k127_6668795_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 286.0
PYH2_k127_6668795_4 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002811 284.0
PYH2_k127_6668795_5 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000387 237.0
PYH2_k127_6668795_6 NIL - - - 0.0000000000000000000000000000000000000000000000000000000018 202.0
PYH2_k127_6668795_7 HAD-hyrolase-like - - - 0.000000000000000000000000000000000000000000005048 171.0
PYH2_k127_6668795_8 Protein of unknown function (DUF3795) - - - 0.00000000000000000000000000000000000002086 150.0
PYH2_k127_6668795_9 AAA domain - - - 0.000000000000000000003165 102.0
PYH2_k127_6681549_0 Heat shock 70 kDa protein K04043 - - 2.045e-313 970.0
PYH2_k127_6681549_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 589.0
PYH2_k127_6681549_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004513 415.0
PYH2_k127_6681549_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 323.0
PYH2_k127_6681549_4 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH2_k127_6681549_5 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000109 235.0
PYH2_k127_6681549_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000298 152.0
PYH2_k127_6681549_7 MFS transporter - - - 0.00000000000000000000000000000000000001447 161.0
PYH2_k127_6681549_8 cellulase activity - - - 0.00000000000000005985 95.0
PYH2_k127_6710011_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 1.522e-202 638.0
PYH2_k127_6710011_1 BadF/BadG/BcrA/BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004273 270.0
PYH2_k127_6714113_0 TIGRFAM glucosamine--fructose-6-phosphate aminotransferase (isomerizing) K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 376.0
PYH2_k127_6714113_1 Ferric uptake regulator family K03711 - - 0.00000000000000000000000000000000000000134 152.0
PYH2_k127_6719322_0 hydrogenase large subunit K06281 - 1.12.99.6 3.277e-237 742.0
PYH2_k127_6719322_1 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 377.0
PYH2_k127_6719322_2 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 369.0
PYH2_k127_6719322_3 NiFe/NiFeSe hydrogenase small subunit C-terminal K06282 - 1.12.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000004242 246.0
PYH2_k127_6719322_4 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000006268 232.0
PYH2_k127_6719322_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000005304 221.0
PYH2_k127_6719322_6 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000005513 179.0
PYH2_k127_6719322_7 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000003417 135.0
PYH2_k127_6719322_8 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000008918 101.0
PYH2_k127_6736428_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 6.345e-276 867.0
PYH2_k127_6736428_1 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.895e-203 636.0
PYH2_k127_6736428_10 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000005991 210.0
PYH2_k127_6736428_11 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000006044 165.0
PYH2_k127_6736428_12 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000000000000000000000000000208 122.0
PYH2_k127_6736428_13 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000005865 110.0
PYH2_k127_6736428_14 Bacterial protein of unknown function (DUF951) - - - 0.00000000000000000000001104 101.0
PYH2_k127_6736428_15 - - - - 0.000000000000000002881 94.0
PYH2_k127_6736428_16 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000002673 85.0
PYH2_k127_6736428_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 546.0
PYH2_k127_6736428_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 487.0
PYH2_k127_6736428_4 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003918 434.0
PYH2_k127_6736428_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 416.0
PYH2_k127_6736428_6 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 374.0
PYH2_k127_6736428_7 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005867 319.0
PYH2_k127_6736428_8 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591,K13421 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.10,4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007373 298.0
PYH2_k127_6736428_9 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 293.0
PYH2_k127_6746120_0 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000964 293.0
PYH2_k127_6746120_1 Peptide ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000007611 250.0
PYH2_k127_6746120_2 B12 binding domain K00548 - 2.1.1.13 0.00000000000000000000000000000000009187 138.0
PYH2_k127_675690_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1107.0
PYH2_k127_675690_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2e-323 1016.0
PYH2_k127_675690_10 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000002464 244.0
PYH2_k127_675690_11 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000008251 193.0
PYH2_k127_675690_12 - - - - 0.0000000000000000000000000000000000000000000000002129 184.0
PYH2_k127_675690_13 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000001492 183.0
PYH2_k127_675690_14 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000007638 136.0
PYH2_k127_675690_15 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000808 138.0
PYH2_k127_675690_16 DNA polymerase X family K02347 - - 0.00000000000007882 76.0
PYH2_k127_675690_2 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 3.425e-244 764.0
PYH2_k127_675690_3 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 529.0
PYH2_k127_675690_4 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 457.0
PYH2_k127_675690_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002894 390.0
PYH2_k127_675690_6 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 384.0
PYH2_k127_675690_7 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007507 309.0
PYH2_k127_675690_8 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 311.0
PYH2_k127_675690_9 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000002609 280.0
PYH2_k127_6766150_0 - - - - 0.0000000000000000000000000000000008819 141.0
PYH2_k127_6766150_1 antibiotic catabolic process - - - 0.0000000005304 61.0
PYH2_k127_6821821_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 620.0
PYH2_k127_6821821_1 introduces a magnesium ion into protoporphyrin IX to yield Mg-protoporphyrin IX K03404,K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 592.0
PYH2_k127_6821821_10 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000005781 156.0
PYH2_k127_6821821_11 lipoprotein biosynthetic process K13292 - - 0.000000000000000000000000000000000003972 148.0
PYH2_k127_6821821_12 response regulator receiver - - - 0.0000000000000000000000000000000000116 153.0
PYH2_k127_6821821_13 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates - - - 0.00000000000000000000000000000003097 130.0
PYH2_k127_6821821_14 NADH-quinone oxidoreductase, E subunit K00334,K18330,K22340 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000000000000000003636 122.0
PYH2_k127_6821821_15 - - - - 0.00000000000000000000000000005702 117.0
PYH2_k127_6821821_16 cheY-homologous receiver domain - - - 0.000000000000000000000001064 109.0
PYH2_k127_6821821_17 - - - - 0.000000000000000000000009769 102.0
PYH2_k127_6821821_18 PFAM response regulator receiver - - - 0.00000000000000000000002242 106.0
PYH2_k127_6821821_19 - - - - 0.000000000000000000000123 98.0
PYH2_k127_6821821_2 Radical SAM superfamily K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 518.0
PYH2_k127_6821821_20 Helix-turn-helix XRE-family like proteins K07729 - - 0.0000000000000000000005337 96.0
PYH2_k127_6821821_21 Glutamine amidotransferase class-I - - - 0.0000000000000000000005569 99.0
PYH2_k127_6821821_22 - - - - 0.000000000000000001787 87.0
PYH2_k127_6821821_23 GIY-YIG catalytic domain K07461 - - 0.00000000000000002447 83.0
PYH2_k127_6821821_24 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000002498 76.0
PYH2_k127_6821821_25 - - - - 0.0000000003595 61.0
PYH2_k127_6821821_26 - - - - 0.000000007808 61.0
PYH2_k127_6821821_3 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335,K18331 - 1.12.1.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000848 423.0
PYH2_k127_6821821_4 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004326 387.0
PYH2_k127_6821821_5 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 311.0
PYH2_k127_6821821_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002691 272.0
PYH2_k127_6821821_7 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000004582 212.0
PYH2_k127_6821821_8 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K22338 - 1.17.1.11 0.000000000000000000000000000000000000000000000000000004262 198.0
PYH2_k127_6821821_9 Domain of unknown function (DUF4157) - - - 0.00000000000000000000000000000000000000000006345 185.0
PYH2_k127_6842509_0 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 359.0
PYH2_k127_6842509_1 CoA-transferase family III K07749 - 2.8.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 324.0
PYH2_k127_6842509_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000001809 120.0
PYH2_k127_6842509_3 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000006458 87.0
PYH2_k127_6842509_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0001562 54.0
PYH2_k127_685132_0 - K03561,K12287 - - 0.0000000000000000000000000000000005703 153.0
PYH2_k127_6853198_0 ABC transporter K06158 - - 5.848e-208 666.0
PYH2_k127_6853198_1 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 506.0
PYH2_k127_6853198_10 reductase K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.000000000000000000000000000000000000000002299 166.0
PYH2_k127_6853198_11 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000001638 68.0
PYH2_k127_6853198_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 468.0
PYH2_k127_6853198_3 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 413.0
PYH2_k127_6853198_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003039 402.0
PYH2_k127_6853198_5 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 387.0
PYH2_k127_6853198_6 O-methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000004533 238.0
PYH2_k127_6853198_7 Large-conductance mechanosensitive channel, MscL K03282 - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH2_k127_6853198_8 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000007092 183.0
PYH2_k127_6853198_9 COG0229 Conserved domain frequently associated with peptide methionine sulfoxide reductase K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000006515 175.0
PYH2_k127_6873421_0 N-terminal domain of galactosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 353.0
PYH2_k127_6873421_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000003926 201.0
PYH2_k127_6888390_0 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009331 386.0
PYH2_k127_6888390_1 Glutamine cyclotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005394 259.0
PYH2_k127_6888390_2 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin K13274,K14645 - - 0.000000000000000000000000000000000000000000000000000000000000001088 231.0
PYH2_k127_6888390_3 Domain of unknown function (DUF4382) - - - 0.0000000000000000000001084 108.0
PYH2_k127_6888390_4 Domain of unknown function (DUF4382) - - - 0.0000008289 61.0
PYH2_k127_6927015_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005861 500.0
PYH2_k127_6927015_1 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 496.0
PYH2_k127_6927015_2 PFAM Integrase catalytic region K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 397.0
PYH2_k127_6927015_3 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.00000000000000000000001013 105.0
PYH2_k127_6927015_4 Probable zinc-ribbon domain - - - 0.0000000000000005378 79.0
PYH2_k127_6927015_5 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000004444 65.0
PYH2_k127_6927015_6 - - - - 0.0000004634 57.0
PYH2_k127_6927015_7 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00004708 49.0
PYH2_k127_6948456_0 Peptide ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000001187 169.0
PYH2_k127_6948456_1 leucine-rich repeat-containing protein typical subtype K13730 - - 0.00000000000000000000000001527 120.0
PYH2_k127_6955732_0 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 358.0
PYH2_k127_6955732_1 Protein of unknown function (DUF2961) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 346.0
PYH2_k127_6955732_10 MaoC like domain - - - 0.00002199 52.0
PYH2_k127_6955732_2 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000104 289.0
PYH2_k127_6955732_3 PFAM von Willebrand factor type A K07114 - - 0.000000000000000000000000000000000000000000000000000006733 210.0
PYH2_k127_6955732_4 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K00980 - 2.7.7.39 0.0000000000000000000000000000000000007085 145.0
PYH2_k127_6955732_5 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000005533 109.0
PYH2_k127_6955732_6 xylan catabolic process K03932 - - 0.00000000000000006135 92.0
PYH2_k127_6955732_7 Short C-terminal domain K08982 - - 0.0000000000004962 72.0
PYH2_k127_6955732_8 dehydratase - - - 0.000002125 55.0
PYH2_k127_698465_0 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000565 261.0
PYH2_k127_698465_1 methyltransferase - - - 0.00000000000000000000000000000000000000000000005606 177.0
PYH2_k127_6991774_0 Belongs to the 'phage' integrase family - - - 0.00000000000000004867 83.0
PYH2_k127_6991774_1 - - - - 0.000007137 53.0
PYH2_k127_7013154_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 1.995e-202 634.0
PYH2_k127_7013154_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003375 264.0
PYH2_k127_7013154_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000001536 241.0
PYH2_k127_7013154_3 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000005158 213.0
PYH2_k127_7041879_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1200.0
PYH2_k127_7041879_1 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000001112 82.0
PYH2_k127_7051219_0 Pyruvate formate lyase-like K00656,K07540 - 2.3.1.54,4.1.99.11 0.00000000000000000000000000000000000000000000000000000000002163 211.0
PYH2_k127_7051219_1 MATE efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000002722 222.0
PYH2_k127_7054339_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.338e-228 715.0
PYH2_k127_7054339_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 9.228e-220 694.0
PYH2_k127_7054339_10 Efflux ABC transporter permease protein K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 330.0
PYH2_k127_7054339_11 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 307.0
PYH2_k127_7054339_12 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 281.0
PYH2_k127_7054339_13 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001067 269.0
PYH2_k127_7054339_14 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001982 254.0
PYH2_k127_7054339_15 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000001871 185.0
PYH2_k127_7054339_16 TIGRFAM primosome, DnaD subunit - - - 0.0000000000000000000000000000000000000004746 159.0
PYH2_k127_7054339_17 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000003021 158.0
PYH2_k127_7054339_18 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000001808 143.0
PYH2_k127_7054339_19 MgtC family K07507 - - 0.00000000000000000000000000000000002562 138.0
PYH2_k127_7054339_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.826e-195 616.0
PYH2_k127_7054339_20 6-O-methylguanine DNA methyltransferase, DNA binding domain - - - 0.000000000000000000002595 95.0
PYH2_k127_7054339_21 methylated-DNA-[protein]-cysteine S-methyltransferase activity K00567 - 2.1.1.63 0.0000000000000000001528 90.0
PYH2_k127_7054339_22 GIY-YIG catalytic domain K07461 - - 0.000000000000003748 76.0
PYH2_k127_7054339_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000007062 88.0
PYH2_k127_7054339_24 Nitroreductase family K04719 - 1.13.11.79 0.00000000000004362 79.0
PYH2_k127_7054339_25 GIY-YIG catalytic domain K07461 - - 0.00000000003867 63.0
PYH2_k127_7054339_26 HlyD family secretion protein K02005 - - 0.00003308 57.0
PYH2_k127_7054339_3 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 517.0
PYH2_k127_7054339_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009513 510.0
PYH2_k127_7054339_5 Bacterial dnaA protein K02315 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006056 479.0
PYH2_k127_7054339_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 463.0
PYH2_k127_7054339_7 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 447.0
PYH2_k127_7054339_8 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 411.0
PYH2_k127_7054339_9 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 366.0
PYH2_k127_7056502_0 Biotin carboxylase C-terminal domain - - - 0.0 1225.0
PYH2_k127_7056502_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 6.706e-304 949.0
PYH2_k127_7056502_10 4Fe-4S ferredoxin iron-sulfur binding domain protein K07307 - - 0.00000000000000000000001713 117.0
PYH2_k127_7056502_11 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000001025 60.0
PYH2_k127_7056502_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 381.0
PYH2_k127_7056502_3 FMN-dependent dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 365.0
PYH2_k127_7056502_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 342.0
PYH2_k127_7056502_5 acetyl-coa acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 311.0
PYH2_k127_7056502_6 Phosphomethylpyrimidine kinase K00852 - 2.7.1.15 0.00000000000000000000000000000000000000000000000000000001133 209.0
PYH2_k127_7056502_7 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000004263 152.0
PYH2_k127_7056502_8 carboxylic ester hydrolase activity K01055 - 3.1.1.24 0.00000000000000000000000000000000001236 144.0
PYH2_k127_7056502_9 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.00000000000000000000000000000001395 143.0
PYH2_k127_7066122_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 570.0
PYH2_k127_7066122_1 Phage portal protein, SPP1 Gp6-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 567.0
PYH2_k127_7066122_11 - - - - 0.0000000000000001436 82.0
PYH2_k127_7066122_12 Belongs to the 'phage' integrase family K04763 - - 0.000000000000007035 87.0
PYH2_k127_7066122_13 - - - - 0.0000000000006311 71.0
PYH2_k127_7066122_14 Concanavalin A-like lectin/glucanases superfamily - - - 0.000000001687 67.0
PYH2_k127_7066122_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 555.0
PYH2_k127_7066122_3 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 488.0
PYH2_k127_7066122_4 Phage capsid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005716 484.0
PYH2_k127_7066122_5 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000007526 231.0
PYH2_k127_7066122_6 PFAM FAD dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000003291 208.0
PYH2_k127_7066122_7 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000182 178.0
PYH2_k127_7066122_8 - - - - 0.000000000000000000000000000000000000000000000002421 180.0
PYH2_k127_7066122_9 - - - - 0.00000000000000000000000000000000009574 134.0
PYH2_k127_7073752_0 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000003547 137.0
PYH2_k127_7073752_1 - - - - 0.000000001856 61.0
PYH2_k127_7073752_2 diguanylate cyclase K13590 - 2.7.7.65 0.0000007958 57.0
PYH2_k127_7106253_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002086 398.0
PYH2_k127_7106253_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000008859 114.0
PYH2_k127_7106253_2 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000016 64.0
PYH2_k127_7124209_0 - - - - 0.000002413 56.0
PYH2_k127_7169039_0 Endoribonuclease that initiates mRNA decay K18682 - - 1.137e-215 680.0
PYH2_k127_7169039_1 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 315.0
PYH2_k127_7169039_2 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 302.0
PYH2_k127_7169039_3 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01908 - 6.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002688 270.0
PYH2_k127_7169039_4 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000002274 200.0
PYH2_k127_7169039_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000006669 203.0
PYH2_k127_7169039_6 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000003866 147.0
PYH2_k127_717455_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007986 258.0
PYH2_k127_7230405_0 DDE superfamily endonuclease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 486.0
PYH2_k127_7230405_1 CoA carboxylase activity K01965,K02160 - 6.4.1.3 0.00000000000000000001301 96.0
PYH2_k127_7230405_2 - K00507 - 1.14.19.1 0.00000000000000001571 95.0
PYH2_k127_7255140_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.012e-207 654.0
PYH2_k127_7255140_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 548.0
PYH2_k127_7255140_10 PFAM beta-lactamase domain protein - - - 0.000000000000000000000000000005237 128.0
PYH2_k127_7255140_11 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.000000000000000000001198 100.0
PYH2_k127_7255140_2 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 479.0
PYH2_k127_7255140_3 RNA pseudouridylate synthase K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 255.0
PYH2_k127_7255140_4 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000001573 225.0
PYH2_k127_7255140_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000000000000003333 214.0
PYH2_k127_7255140_6 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000000000000007623 212.0
PYH2_k127_7255140_7 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.00000000000000000000000000000000000000000000005206 175.0
PYH2_k127_7255140_8 7 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase K00950,K09007,K13940,K17488 - 2.7.6.3,3.5.4.16,3.5.4.39,4.1.2.25 0.00000000000000000000000000000000000000004116 156.0
PYH2_k127_7255140_9 4fe-4S ferredoxin, iron-sulfur binding domain protein K03522,K05337 - - 0.000000000000000000000000000002037 121.0
PYH2_k127_7293913_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 340.0
PYH2_k127_7293913_1 PFAM ThiJ PfpI domain protein - - - 0.00000000000000000000000000000000000000000000000000000009139 198.0
PYH2_k127_7300212_0 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 351.0
PYH2_k127_7300212_1 Domain of unknown function (DUF4382) - - - 0.000000000000000000000006211 108.0
PYH2_k127_7300360_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 467.0
PYH2_k127_7300360_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 380.0
PYH2_k127_7300360_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000001773 235.0
PYH2_k127_7300360_3 Arsenite-activated ATPase ArsA K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000004118 193.0
PYH2_k127_7300360_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000001523 180.0
PYH2_k127_7300360_5 Domain of unknown function (DUF4342) - - - 0.00000000003924 68.0
PYH2_k127_7300360_6 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.0000000239 55.0
PYH2_k127_7324069_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 604.0
PYH2_k127_7324069_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 436.0
PYH2_k127_7324069_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 335.0
PYH2_k127_7324069_3 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000008966 248.0
PYH2_k127_7324069_4 Colicin V production protein K03558 - - 0.000000000000000000000000000002356 132.0
PYH2_k127_7324069_5 AMP binding - - - 0.00000000000000000009757 96.0
PYH2_k127_7324069_6 - - - - 0.0000000006944 63.0
PYH2_k127_732976_0 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 444.0
PYH2_k127_738505_0 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004134 322.0
PYH2_k127_738505_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000005438 226.0
PYH2_k127_738505_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000001235 190.0
PYH2_k127_738505_3 Acetyltransferase (GNAT) domain - - - 0.000009185 54.0
PYH2_k127_738505_4 Carboxylesterase family K03929 - - 0.0008996 43.0
PYH2_k127_738775_0 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005066 464.0
PYH2_k127_7422874_0 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004577 251.0
PYH2_k127_7422874_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000003096 243.0
PYH2_k127_7422874_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000003785 202.0
PYH2_k127_7422874_3 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000002027 166.0
PYH2_k127_7422874_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000132 157.0
PYH2_k127_7422874_5 PFAM Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000003666 114.0
PYH2_k127_7422874_6 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000004464 117.0
PYH2_k127_7430129_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006307 419.0
PYH2_k127_7430129_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000502 88.0
PYH2_k127_7430129_2 Belongs to the CarA family K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.00000004551 55.0
PYH2_k127_7432553_0 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006439 278.0
PYH2_k127_7432553_1 Glycosyl hydrolases family 2, sugar binding domain - - - 0.00000000000000000000001664 103.0
PYH2_k127_7432553_2 - - - - 0.00000000000000843 88.0
PYH2_k127_7435103_0 Toxic anion resistance - - - 0.0000000000000000000000000000000000000005288 164.0
PYH2_k127_7435103_1 Protein tyrosine kinase - - - 0.0000000000000000000000000000000001573 152.0
PYH2_k127_7435103_2 Dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000003871 123.0
PYH2_k127_7492384_0 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 4.971e-204 643.0
PYH2_k127_7492384_1 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 393.0
PYH2_k127_7492384_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006988 299.0
PYH2_k127_7492384_3 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001096 275.0
PYH2_k127_7492384_4 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000176 266.0
PYH2_k127_7492384_5 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000007865 227.0
PYH2_k127_7492384_6 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000849 199.0
PYH2_k127_7492384_7 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000006516 149.0
PYH2_k127_7492384_8 - - - - 0.00000000000000000000001572 108.0
PYH2_k127_7548288_0 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000007168 224.0
PYH2_k127_7548288_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015935,GO:0016020,GO:0016043,GO:0017148,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065003,GO:0065007,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.0000000000000000000000000000000000000000000000000003149 189.0
PYH2_k127_7548288_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000003861 64.0
PYH2_k127_7566369_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 359.0
PYH2_k127_7566369_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000005338 145.0
PYH2_k127_7566369_2 - - - - 0.00000000000000242 82.0
PYH2_k127_7566369_3 helix_turn_helix, Lux Regulon - - - 0.0000000000002827 76.0
PYH2_k127_7566369_4 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K00558,K13639,K13640 - 2.1.1.37 0.000000000003697 68.0
PYH2_k127_7586321_0 Tail sheath protein K06907 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 598.0
PYH2_k127_7586321_1 Phage late control gene D protein (GPD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003751 271.0
PYH2_k127_7586321_2 LysM domain - - - 0.0000000000000000000000000000000000000000000000000000000000003126 217.0
PYH2_k127_7586321_3 T4-like virus tail tube protein gp19 - - - 0.000000000000000000000000000000000000000000009647 166.0
PYH2_k127_7586321_4 - - - - 0.000000000000000000000000000000000000000002596 158.0
PYH2_k127_7586321_5 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000004779 148.0
PYH2_k127_7586321_6 Protein of unknown function (DUF4255) - - - 0.0000000000000000000000000000001631 134.0
PYH2_k127_7586321_7 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000004316 121.0
PYH2_k127_7586321_8 - - - - 0.000000000008022 70.0
PYH2_k127_7593504_0 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 501.0
PYH2_k127_7593504_1 NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 307.0
PYH2_k127_7593504_2 Trypsin-like serine protease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001988 267.0
PYH2_k127_7593504_3 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.00000000000000000000000000000000000000000000000000000001106 201.0
PYH2_k127_7593504_4 GYD domain - - - 0.000000000000000008087 87.0
PYH2_k127_7593504_5 - - - - 0.0000002329 56.0
PYH2_k127_7598550_0 Conserved region in glutamate synthase - - - 1.318e-262 815.0
PYH2_k127_7598550_1 Glutamine amidotransferases class-II - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006073 562.0
PYH2_k127_7598550_2 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 545.0
PYH2_k127_7598550_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 366.0
PYH2_k127_7598550_4 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008384 318.0
PYH2_k127_7598550_5 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000006851 154.0
PYH2_k127_7616307_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1625.0
PYH2_k127_7616307_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 515.0
PYH2_k127_7616307_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000659 125.0
PYH2_k127_7634553_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 1.728e-217 691.0
PYH2_k127_7634553_1 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003586 470.0
PYH2_k127_7634553_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000005006 186.0
PYH2_k127_7641827_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000003214 102.0
PYH2_k127_7641827_1 Bacterial regulatory proteins, tetR family - - - 0.0000000000000004759 87.0
PYH2_k127_7641827_2 Cobalamin synthesis protein cobW C-terminal domain - - - 0.00000001649 63.0
PYH2_k127_7673108_0 Belongs to the peptidase S8 family - - - 0.000000000000000000000000000000000000001767 171.0
PYH2_k127_7673108_1 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.0000000000000000000003 102.0
PYH2_k127_7673628_0 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000000001179 188.0
PYH2_k127_7673628_1 Transposase - - - 0.00000000000000000000000000000000000005643 148.0
PYH2_k127_7673628_2 COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000002519 121.0
PYH2_k127_7673628_3 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.00000000000001042 80.0
PYH2_k127_7682283_0 Carboxyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000908 311.0
PYH2_k127_7682283_1 CoA-transferase family III K07749 - 2.8.3.16 0.000000000000000374 82.0
PYH2_k127_7694506_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000005048 220.0
PYH2_k127_7718643_1 protein transport across the cell outer membrane - - - 0.0000368 49.0
PYH2_k127_7830932_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 593.0
PYH2_k127_7830932_1 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000003476 71.0
PYH2_k127_7843295_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.1e-281 884.0
PYH2_k127_7843295_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.102e-241 754.0
PYH2_k127_7843295_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000002358 164.0
PYH2_k127_7843295_11 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000004143 162.0
PYH2_k127_7843295_12 Zincin-like metallopeptidase - - - 0.00000000000000000000000000001565 121.0
PYH2_k127_7843295_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000007069 119.0
PYH2_k127_7843295_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000002508 98.0
PYH2_k127_7843295_16 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 - 0.00000000000000002656 82.0
PYH2_k127_7843295_17 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.000000000000001454 79.0
PYH2_k127_7843295_19 - - - - 0.000000002929 63.0
PYH2_k127_7843295_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.949e-237 740.0
PYH2_k127_7843295_3 PFAM AMP-dependent synthetase and ligase K00666 - - 3.229e-213 676.0
PYH2_k127_7843295_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005417 535.0
PYH2_k127_7843295_5 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009705 385.0
PYH2_k127_7843295_6 Nitroreductase family K19285 - 1.5.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000251 261.0
PYH2_k127_7843295_7 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008793 263.0
PYH2_k127_7843295_8 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
PYH2_k127_7843295_9 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000003041 189.0
PYH2_k127_7891590_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 1.886e-287 904.0
PYH2_k127_7891590_1 Formate dehydrogenase iron-sulfur subunit K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007817 250.0
PYH2_k127_7891590_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.0001674 47.0
PYH2_k127_7891590_11 Elongation factor SelB, winged helix K03833 - - 0.0006531 44.0
PYH2_k127_7891590_2 PFAM Molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000009473 209.0
PYH2_k127_7891590_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000000000000000000000000000000000000000000000000023 196.0
PYH2_k127_7891590_4 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000011 194.0
PYH2_k127_7891590_5 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000006924 133.0
PYH2_k127_7891590_6 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000009216 136.0
PYH2_k127_7891590_7 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000003788 125.0
PYH2_k127_7891590_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000008591 62.0
PYH2_k127_7891590_9 - - - - 0.00000819 53.0
PYH2_k127_7907595_0 COG0534 Na -driven multidrug efflux pump - - - 0.000000000000000000000000000000000000000000002709 180.0
PYH2_k127_7907595_1 - - - - 0.00009187 53.0
PYH2_k127_7911885_0 Domain of unknown function (DUF4070) - - - 3.594e-201 638.0
PYH2_k127_7911885_1 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 491.0
PYH2_k127_7911885_10 calcium proton exchanger K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001407 270.0
PYH2_k127_7911885_11 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000716 222.0
PYH2_k127_7911885_12 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000001319 222.0
PYH2_k127_7911885_13 PFAM Transglutaminase-like - - - 0.00000000000000000000000000000001079 134.0
PYH2_k127_7911885_14 SNARE associated Golgi protein - - - 0.000000000000000000000000000001362 129.0
PYH2_k127_7911885_15 Protease prsW family - - - 0.0000000000000000000000000000081 130.0
PYH2_k127_7911885_16 - - - - 0.00000000000000000000000002253 109.0
PYH2_k127_7911885_17 RDD family - - - 0.00000000000000000009483 97.0
PYH2_k127_7911885_18 - - - - 0.000000000000239 75.0
PYH2_k127_7911885_19 Antibiotic biosynthesis monooxygenase - - - 0.000000000006527 69.0
PYH2_k127_7911885_2 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 386.0
PYH2_k127_7911885_20 - - - - 0.0000166 49.0
PYH2_k127_7911885_21 - - - - 0.00005735 51.0
PYH2_k127_7911885_3 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 363.0
PYH2_k127_7911885_4 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008003 351.0
PYH2_k127_7911885_5 Acyl-CoA dehydrogenase, middle domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 343.0
PYH2_k127_7911885_6 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 334.0
PYH2_k127_7911885_7 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004033 324.0
PYH2_k127_7911885_8 CorA-like Mg2+ transporter protein K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 299.0
PYH2_k127_7911885_9 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000315 263.0
PYH2_k127_7932286_0 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 471.0
PYH2_k127_7932286_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002931 275.0
PYH2_k127_7932286_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001195 250.0
PYH2_k127_7932286_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034,K00038,K00046 - 1.1.1.47,1.1.1.53,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
PYH2_k127_7932286_4 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.0000000000000002991 83.0
PYH2_k127_7940731_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.068e-260 812.0
PYH2_k127_7940731_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.746e-198 624.0
PYH2_k127_7940731_10 PFAM Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009207 320.0
PYH2_k127_7940731_11 PSP1 C-terminal conserved region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 314.0
PYH2_k127_7940731_12 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 287.0
PYH2_k127_7940731_13 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007084 286.0
PYH2_k127_7940731_14 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000527 274.0
PYH2_k127_7940731_15 Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 260.0
PYH2_k127_7940731_16 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000009953 243.0
PYH2_k127_7940731_17 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000004072 209.0
PYH2_k127_7940731_18 HAD hydrolase, family IA, variant 1 K07025 - - 0.00000000000000000000000000000000000000000000003909 178.0
PYH2_k127_7940731_19 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000006556 156.0
PYH2_k127_7940731_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 616.0
PYH2_k127_7940731_20 HNH endonuclease - - - 0.000000000000000000000000000000000007988 139.0
PYH2_k127_7940731_21 COG2133 Glucose sorbosone dehydrogenases - - - 0.000000000000000000000000001527 117.0
PYH2_k127_7940731_22 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000001815 100.0
PYH2_k127_7940731_23 Methyltransferase type 11 - - - 0.00000000000000000001417 102.0
PYH2_k127_7940731_24 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.00000000000000004311 93.0
PYH2_k127_7940731_25 cell adhesion involved in biofilm formation - - - 0.0008963 51.0
PYH2_k127_7940731_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 516.0
PYH2_k127_7940731_4 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 386.0
PYH2_k127_7940731_5 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 366.0
PYH2_k127_7940731_6 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 363.0
PYH2_k127_7940731_7 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 352.0
PYH2_k127_7940731_8 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 359.0
PYH2_k127_7940731_9 4Fe-4S double cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 349.0
PYH2_k127_7970978_0 Helix-turn-helix domain - - - 0.0000000106 61.0
PYH2_k127_7970978_1 - - - - 0.00000006724 56.0
PYH2_k127_8021450_0 TIGRFAM addiction module antidote protein, HigA family K21498 - - 0.00000000000000000002095 95.0
PYH2_k127_8021450_1 DEAD-like helicases superfamily - - - 0.0000000000001251 71.0
PYH2_k127_8021450_2 DDE superfamily endonuclease K07494 - - 0.0000000000008086 75.0
PYH2_k127_8021450_3 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000001775 61.0
PYH2_k127_8021450_4 Winged helix-turn helix - - - 0.0000008791 57.0
PYH2_k127_8021450_5 Helix-turn-helix XRE-family like proteins K21498 - - 0.0001668 44.0
PYH2_k127_8034888_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.00000002505 67.0
PYH2_k127_8087766_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1038.0
PYH2_k127_8087766_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 447.0
PYH2_k127_8087766_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000006312 119.0
PYH2_k127_8087766_11 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000002228 70.0
PYH2_k127_8087766_12 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.00000000004708 74.0
PYH2_k127_8087766_13 COG3291 FOG PKD repeat - - - 0.0001465 53.0
PYH2_k127_8087766_2 Belongs to the ABC transporter superfamily K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 434.0
PYH2_k127_8087766_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 315.0
PYH2_k127_8087766_4 3-hydroxyacyl-CoA dehydrogenase domain protein K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000417 275.0
PYH2_k127_8087766_5 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
PYH2_k127_8087766_6 Belongs to the enoyl-CoA hydratase isomerase family K07546,K08299,K15866 - 4.2.1.149,5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000008417 228.0
PYH2_k127_8087766_7 ABC-type uncharacterized transport system K01992 - - 0.0000000000000000000000000000000000000000000000000102 199.0
PYH2_k127_8087766_8 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000001138 185.0
PYH2_k127_8087766_9 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000001251 136.0
PYH2_k127_8126659_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000003698 216.0
PYH2_k127_8126659_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000003257 200.0
PYH2_k127_8126659_2 MaoC like domain - - - 0.00000000000000000000000000000000000006599 146.0
PYH2_k127_8126659_3 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000286 116.0
PYH2_k127_8126659_4 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000005712 57.0
PYH2_k127_8126659_5 ABC-2 type transporter K01992 - - 0.000000008057 58.0
PYH2_k127_8142665_0 transposase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 298.0
PYH2_k127_8170008_0 PFAM Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 612.0
PYH2_k127_8170008_1 acid phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 378.0
PYH2_k127_8170008_2 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 366.0
PYH2_k127_8170008_3 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 297.0
PYH2_k127_8170008_4 PFAM Cytochrome C assembly protein K02195 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003736 263.0
PYH2_k127_8170008_5 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002965 263.0
PYH2_k127_8170008_6 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000000000000002323 252.0
PYH2_k127_8170008_7 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000000000000000000000000000000000205 183.0
PYH2_k127_8170008_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000114 128.0
PYH2_k127_8171847_0 Penicillin amidase K01434 - 3.5.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 370.0
PYH2_k127_8191550_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 444.0
PYH2_k127_8191550_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 315.0
PYH2_k127_8191550_2 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001044 258.0
PYH2_k127_8191550_3 PFAM HD domain - - - 0.000000000000000000000000000000000000000000005096 170.0
PYH2_k127_8191550_4 ThiF family K21029,K21147 - 2.7.7.80,2.8.1.11 0.00001004 51.0
PYH2_k127_8192498_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001875 288.0
PYH2_k127_8195906_0 gluconolactonase activity - - - 0.0000000000000000000007504 108.0
PYH2_k127_8234402_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 488.0
PYH2_k127_8234402_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000002312 224.0
PYH2_k127_8234402_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000006669 91.0
PYH2_k127_8260693_0 Thermophilic metalloprotease (M29) K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005611 528.0
PYH2_k127_8260693_1 PFAM acyl-CoA dehydrogenase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001306 281.0
PYH2_k127_8260693_2 metal-dependent hydrolase of the TIM-barrel fold K07045 - - 0.00000000000000000000000000000000000000000001717 164.0
PYH2_k127_8330969_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 309.0
PYH2_k127_8330969_1 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000002254 124.0
PYH2_k127_8343174_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000528 273.0
PYH2_k127_8343174_1 Oligopeptidase F K08602 - - 0.000000000000000000000000000000000000000003561 157.0
PYH2_k127_8352403_0 Multicopper oxidase K22349 - 1.16.3.3 0.0000000000000000134 84.0
PYH2_k127_8356507_0 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 591.0
PYH2_k127_8356507_1 Aminotransferase class I and II K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 556.0
PYH2_k127_8356507_10 Domain of unknown function (DUF4389) - - - 0.0000000000000000000000000000000000000000000000000000000002442 211.0
PYH2_k127_8356507_11 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000001154 178.0
PYH2_k127_8356507_12 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000127 166.0
PYH2_k127_8356507_13 RNA recognition motif - - - 0.0000000000000000000000000000001802 126.0
PYH2_k127_8356507_14 SpoVT / AbrB like domain - - - 0.0000000001449 66.0
PYH2_k127_8356507_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 426.0
PYH2_k127_8356507_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 418.0
PYH2_k127_8356507_4 Iron-sulfur cluster-binding domain K06871 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 403.0
PYH2_k127_8356507_5 fructose-1,6-bisphosphatase K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 384.0
PYH2_k127_8356507_6 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 303.0
PYH2_k127_8356507_7 PFAM CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 302.0
PYH2_k127_8356507_8 Sulfatase K01133 - 3.1.6.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 302.0
PYH2_k127_8356507_9 COG2015, Alkyl sulfatase and related hydrolases - - - 0.00000000000000000000000000000000000000000000000000000000000000000008672 246.0
PYH2_k127_8406859_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 580.0
PYH2_k127_8406859_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 302.0
PYH2_k127_8406859_2 Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities K01656,K13501 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0004425,GO:0004640,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0016832,GO:0016833,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0033984,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.1.1.48,4.1.3.27,5.3.1.24 0.00000000000000000000006187 100.0
PYH2_k127_8406859_3 - - - - 0.0000000000004666 72.0
PYH2_k127_8406859_4 Signal peptide protein - - - 0.0000000001388 65.0
PYH2_k127_8414677_0 PFAM transposase, mutator type K07493 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 432.0
PYH2_k127_8414677_1 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 297.0
PYH2_k127_8423445_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 436.0
PYH2_k127_8423445_1 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K01055,K01259,K09023,K14727,K16434 GO:0006139,GO:0006206,GO:0006208,GO:0006212,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0017144,GO:0019740,GO:0019860,GO:0034641,GO:0042737,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072527,GO:0072529,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.1.1.24,3.4.11.5,4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000003348 236.0
PYH2_k127_8423445_2 Aldehyde ferredoxin oxidoreductase, domains 2 & 3 K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000242 194.0
PYH2_k127_8439387_0 Glycosyl transferases group 1 K20444 - - 0.0000000000000000000000000000000000000000000000000086 186.0
PYH2_k127_8439387_1 Sulfotransferase family - - - 0.00000000000000000000000005064 111.0
PYH2_k127_8483806_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 2.443e-280 884.0
PYH2_k127_8483806_1 elongation factor Tu domain 2 protein K02355 - - 4.64e-196 632.0
PYH2_k127_8483806_10 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000007233 203.0
PYH2_k127_8483806_11 TIGRFAM hydrolase, TatD family K03424 - - 0.000000000000000000000000000000000000001138 154.0
PYH2_k127_8483806_12 Ferric uptake regulator family K03711 - - 0.0000000000000000000000000000000001125 137.0
PYH2_k127_8483806_13 MFS_1 like family - - - 0.000000000000000000000000000000001454 149.0
PYH2_k127_8483806_14 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000002686 134.0
PYH2_k127_8483806_15 glutaredoxin-like protein, YruB-family - - - 0.000000000000000000002035 94.0
PYH2_k127_8483806_16 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000002255 79.0
PYH2_k127_8483806_17 - - - - 0.000000000000000227 81.0
PYH2_k127_8483806_18 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000001418 72.0
PYH2_k127_8483806_19 - - - - 0.000001012 54.0
PYH2_k127_8483806_2 Peptidase dimerisation domain K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 461.0
PYH2_k127_8483806_3 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 455.0
PYH2_k127_8483806_4 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 406.0
PYH2_k127_8483806_5 double-stranded DNA 3'-5' exodeoxyribonuclease activity K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 349.0
PYH2_k127_8483806_6 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 336.0
PYH2_k127_8483806_7 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 293.0
PYH2_k127_8483806_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004885 233.0
PYH2_k127_8483806_9 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000005159 205.0
PYH2_k127_8487795_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000589 318.0
PYH2_k127_8487795_1 Sulfatase K01133 - 3.1.6.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007248 286.0
PYH2_k127_8540743_0 PFAM NADH ubiquinone K14128 - 1.8.98.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 379.0
PYH2_k127_8540743_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000001421 118.0
PYH2_k127_8540743_2 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000005982 102.0
PYH2_k127_8541179_0 Dak1_2 K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 498.0
PYH2_k127_8541179_1 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 289.0
PYH2_k127_8541179_2 Uncharacterised protein, DegV family COG1307 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002734 276.0
PYH2_k127_8541179_3 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.00003664 51.0
PYH2_k127_8545954_0 Transposase and inactivated derivatives-like protein - - - 0.00000000000000000000000000001507 131.0
PYH2_k127_8545954_1 transposition, DNA-mediated - - - 0.0001124 46.0
PYH2_k127_8574621_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 369.0
PYH2_k127_8574916_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009511 486.0
PYH2_k127_8574916_1 carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 386.0
PYH2_k127_8574916_10 3-hydroxyacyl-CoA dehydrogenase K00074,K15016,K15019 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0043956 1.1.1.157,1.1.1.35,4.2.1.116,4.2.1.17 0.000000000000000000000000000000000000000001046 166.0
PYH2_k127_8574916_11 Cytidine and deoxycytidylate deaminase zinc-binding region - - - 0.00000000000000000000000000000000000006047 146.0
PYH2_k127_8574916_12 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.000000000000000000000000005485 115.0
PYH2_k127_8574916_2 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 346.0
PYH2_k127_8574916_3 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 310.0
PYH2_k127_8574916_4 IMP dehydrogenase / GMP reductase domain K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009085 306.0
PYH2_k127_8574916_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001521 282.0
PYH2_k127_8574916_6 COG2070 Dioxygenases related to 2-nitropropane dioxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007261 280.0
PYH2_k127_8574916_7 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004272 282.0
PYH2_k127_8574916_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000004381 251.0
PYH2_k127_8574916_9 Exonuclease of the beta-lactamase fold involved in RNA processing K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009427 247.0
PYH2_k127_8588100_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 473.0
PYH2_k127_8588100_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000000000000000000000000000000000000001181 243.0
PYH2_k127_8588100_2 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.00000000000000000000000000000000000000000000000000000004125 203.0
PYH2_k127_8588100_3 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis - - - 0.0000000000000000000000000000000000000000000000001608 187.0
PYH2_k127_8588100_4 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000003636 115.0
PYH2_k127_8588100_5 R3H domain - - - 0.00000000000000000002984 92.0
PYH2_k127_86015_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1313.0
PYH2_k127_86015_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.84e-203 641.0
PYH2_k127_86015_2 Terminase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 580.0
PYH2_k127_86015_3 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 428.0
PYH2_k127_86015_4 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 299.0
PYH2_k127_86015_5 KH domain K06346 - - 0.00000000000000000000000000000000000000000000000143 185.0
PYH2_k127_86015_6 60Kd inner membrane protein K03217 - - 0.000000000000000000000000000000000000000009097 159.0
PYH2_k127_86015_7 - - - - 0.000000000000000000000000000000000001199 142.0
PYH2_k127_86015_8 phosphoglycerate mutase K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000000000002787 130.0
PYH2_k127_86015_9 Zn-ribbon protein possibly nucleic acid-binding K07164 - - 0.0000000000000000000000002687 114.0
PYH2_k127_8606571_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004025 316.0
PYH2_k127_8606571_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 287.0
PYH2_k127_8606571_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000002123 201.0
PYH2_k127_8606571_3 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000004363 156.0
PYH2_k127_8606571_4 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000008221 157.0
PYH2_k127_8606571_5 PFAM response regulator receiver - - - 0.000000000000000000000001481 108.0
PYH2_k127_8606571_6 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.0004252 49.0
PYH2_k127_8618273_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000001195 188.0
PYH2_k127_8618273_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.0000000000000001156 85.0
PYH2_k127_8628641_0 - K03561,K12287 - - 0.000000000000000000000000000000000000000000000000000000008278 218.0
PYH2_k127_8640137_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.457e-299 932.0
PYH2_k127_8640137_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.288e-294 919.0
PYH2_k127_8640137_10 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 301.0
PYH2_k127_8640137_11 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005522 293.0
PYH2_k127_8640137_12 TrkA-C domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002554 284.0
PYH2_k127_8640137_13 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000000000000000000007835 249.0
PYH2_k127_8640137_14 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000000000000009515 214.0
PYH2_k127_8640137_15 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000004989 203.0
PYH2_k127_8640137_16 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.0000000000000000000000000000000000000000000000000000005326 201.0
PYH2_k127_8640137_17 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000007457 192.0
PYH2_k127_8640137_18 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000001741 194.0
PYH2_k127_8640137_19 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000000000004346 176.0
PYH2_k127_8640137_2 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 567.0
PYH2_k127_8640137_20 Glycoprotease family - - - 0.000000000000000000000000000000000000000000000007032 181.0
PYH2_k127_8640137_21 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000004429 177.0
PYH2_k127_8640137_22 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000151 172.0
PYH2_k127_8640137_23 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000006226 168.0
PYH2_k127_8640137_24 Universal stress protein family - - - 0.00000000000000000000000000000000000000000002621 164.0
PYH2_k127_8640137_25 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000005361 167.0
PYH2_k127_8640137_26 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000008737 156.0
PYH2_k127_8640137_27 Domain of unknown function (DU1801) - - - 0.0000000000000000000000000000000000000641 147.0
PYH2_k127_8640137_28 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000006592 132.0
PYH2_k127_8640137_29 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000008356 133.0
PYH2_k127_8640137_3 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002929 541.0
PYH2_k127_8640137_30 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000002951 136.0
PYH2_k127_8640137_31 Cupin domain - - - 0.000000000000000000000000000004316 123.0
PYH2_k127_8640137_32 Prokaryotic dksA/traR C4-type zinc finger - - - 0.00000000000000000000000000001548 121.0
PYH2_k127_8640137_33 thiolester hydrolase activity K03186 - 2.5.1.129 0.000000000000000000000002463 108.0
PYH2_k127_8640137_34 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000001114 108.0
PYH2_k127_8640137_35 RDD family - - - 0.0000000000000000000001455 104.0
PYH2_k127_8640137_36 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000001244 80.0
PYH2_k127_8640137_37 NifU-like domain - - - 0.000000000001779 67.0
PYH2_k127_8640137_38 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06996 - - 0.000000000008962 70.0
PYH2_k127_8640137_39 NifU-like domain - - - 0.00001323 47.0
PYH2_k127_8640137_4 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 469.0
PYH2_k127_8640137_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000721 466.0
PYH2_k127_8640137_6 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 396.0
PYH2_k127_8640137_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 388.0
PYH2_k127_8640137_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 321.0
PYH2_k127_8640137_9 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 304.0
PYH2_k127_8665695_0 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007224 342.0
PYH2_k127_8665695_1 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000001464 157.0
PYH2_k127_8665695_2 Colicin V production protein K03558 - - 0.00000000000000000000000000003154 126.0
PYH2_k127_8665695_3 Domain of unknown function (DUF4445) - - - 0.0000000006399 61.0
PYH2_k127_8728064_0 AMP-binding enzyme K01897 - 6.2.1.3 9.613e-293 911.0
PYH2_k127_8728064_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 401.0
PYH2_k127_8728064_2 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000001506 244.0
PYH2_k127_8728064_3 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000001855 207.0
PYH2_k127_873559_0 FAD binding domain K00239,K00278 - 1.3.5.1,1.3.5.4,1.4.3.16 7.948e-243 760.0
PYH2_k127_873559_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002358 607.0
PYH2_k127_873559_10 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000005473 121.0
PYH2_k127_873559_11 tetratricopeptide repeat - - - 0.000000000000000000000005503 112.0
PYH2_k127_873559_12 LamG domain protein jellyroll fold domain protein - - - 0.00000000002955 71.0
PYH2_k127_873559_13 COG NOG16874 non supervised orthologous group - - - 0.0001486 49.0
PYH2_k127_873559_2 PFAM ABC transporter transmembrane region K06147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 588.0
PYH2_k127_873559_3 ABC transporter, transmembrane region K06147,K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000397 558.0
PYH2_k127_873559_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008054 512.0
PYH2_k127_873559_5 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 355.0
PYH2_k127_873559_6 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 306.0
PYH2_k127_873559_7 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004875 248.0
PYH2_k127_873559_8 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000005196 172.0
PYH2_k127_873559_9 metal-dependent hydrolase of the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000007314 171.0
PYH2_k127_884934_0 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 359.0
PYH2_k127_884934_1 N-terminal TM domain of oligopeptide transport permease C K02034,K15582 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008128 330.0
PYH2_k127_884934_2 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000005394 252.0
PYH2_k127_884934_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000005283 224.0
PYH2_k127_884934_4 PFAM Nitroreductase family - - - 0.0000000000000000000000000000000000000000007675 163.0
PYH2_k127_884934_5 Transcriptional regulator - - - 0.00000000000000000000000000000000005529 141.0
PYH2_k127_8900928_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000006983 226.0
PYH2_k127_8910615_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 1.81e-286 893.0
PYH2_k127_8910615_1 Dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 318.0
PYH2_k127_8910615_2 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 313.0
PYH2_k127_8910615_3 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002033 278.0
PYH2_k127_8910615_4 Belongs to the enoyl-CoA hydratase isomerase family K15019 - 4.2.1.116 0.0000000000000000000000000000000007473 138.0
PYH2_k127_8913708_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 375.0
PYH2_k127_8913708_1 TIGRFAM competence damage-inducible protein CinA N-terminal domain K03742 - 3.5.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 296.0
PYH2_k127_8913708_2 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000002903 59.0
PYH2_k127_8935356_0 Belongs to the ClpA ClpB family K03696 - - 0.0 1170.0
PYH2_k127_8935356_1 Telomere recombination K04656 - - 1.516e-273 861.0
PYH2_k127_8935356_10 MafB19-like deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000002081 261.0
PYH2_k127_8935356_11 efflux protein, MATE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001356 256.0
PYH2_k127_8935356_12 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007483 258.0
PYH2_k127_8935356_13 efflux protein, MATE family - - - 0.0000000000000000000000000000000000000000000000000000000000000000001424 247.0
PYH2_k127_8935356_14 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000001018 211.0
PYH2_k127_8935356_15 Mate efflux family protein - - - 0.000000000000000000000000000000000000000000000000000000001791 218.0
PYH2_k127_8935356_16 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000008376 199.0
PYH2_k127_8935356_17 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000009682 187.0
PYH2_k127_8935356_18 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000000000009493 170.0
PYH2_k127_8935356_19 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000102 173.0
PYH2_k127_8935356_2 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 499.0
PYH2_k127_8935356_20 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000001291 173.0
PYH2_k127_8935356_21 NUDIX domain - GO:0003674,GO:0003824,GO:0016787,GO:0016817,GO:0016818 - 0.000000000000000000000000000000000000006955 152.0
PYH2_k127_8935356_22 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000004251 140.0
PYH2_k127_8935356_23 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000208 151.0
PYH2_k127_8935356_24 NUDIX domain - - - 0.000000000000000000000000000003137 126.0
PYH2_k127_8935356_25 Serine aminopeptidase, S33 - - - 0.000000000000000000000000006299 121.0
PYH2_k127_8935356_26 PFAM SpoVT AbrB domain protein K07172 - - 0.000000000000000000000000008245 115.0
PYH2_k127_8935356_27 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000008757 102.0
PYH2_k127_8935356_28 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000009509 93.0
PYH2_k127_8935356_29 HupF/HypC family K04653 - - 0.000000000000000004345 85.0
PYH2_k127_8935356_3 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 488.0
PYH2_k127_8935356_30 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000004824 86.0
PYH2_k127_8935356_31 - - - - 0.000000000000000521 88.0
PYH2_k127_8935356_32 PFAM glycine cleavage H-protein - - - 0.0000000000001075 79.0
PYH2_k127_8935356_33 cellular response to starvation - GO:0006950,GO:0007154,GO:0008150,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0042594,GO:0050896,GO:0051716,GO:0071496 - 0.00000000000415 70.0
PYH2_k127_8935356_34 Tellurite resistance protein TehB - - - 0.00000000003419 66.0
PYH2_k127_8935356_35 - - - - 0.000002199 53.0
PYH2_k127_8935356_36 - - - - 0.0003504 43.0
PYH2_k127_8935356_4 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 429.0
PYH2_k127_8935356_5 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 369.0
PYH2_k127_8935356_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009876 347.0
PYH2_k127_8935356_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145,K05829 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 346.0
PYH2_k127_8935356_8 Bacterial regulatory proteins, luxR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 286.0
PYH2_k127_8935356_9 acyl-CoA transferases carnitine dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001134 275.0
PYH2_k127_8959505_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 8.191e-229 733.0
PYH2_k127_8959505_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 407.0
PYH2_k127_8959505_2 Hypothetical methyltransferase - - - 0.0000000000000000000001808 105.0
PYH2_k127_8972119_0 Part of the ABC transporter complex LolCDE involved in the translocation of K09810 - - 0.000000000000000000000000000000000000000000000000000000000005363 215.0
PYH2_k127_8972119_1 Efflux ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000000000000000001045 221.0
PYH2_k127_8972119_2 Domain of unknown function (DUF4418) - - - 0.00000000000002116 78.0
PYH2_k127_8972119_3 Cupredoxin-like domain - - - 0.00000000004867 74.0
PYH2_k127_8972119_4 PFAM multicopper oxidase K22348 - 1.16.3.3 0.00006664 48.0
PYH2_k127_8977611_0 pyrroloquinoline quinone binding - - - 3.077e-282 904.0
PYH2_k127_8977611_1 TIGRFAM death-on-curing family protein K07341 - - 0.000000000000000000000000000499 115.0
PYH2_k127_8977611_2 PFAM SpoVT AbrB K07172,K18842 - - 0.00000000000000000000005389 100.0
PYH2_k127_9077103_0 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007541 591.0
PYH2_k127_9077103_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 327.0
PYH2_k127_9077103_10 BioD-like N-terminal domain of phosphotransacetylase K06873 - - 0.00000000000000000000000000000000000000008063 163.0
PYH2_k127_9077103_11 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000000000000000001044 133.0
PYH2_k127_9077103_12 NifU-like N terminal domain K04488 - - 0.00004626 46.0
PYH2_k127_9077103_13 Protein of unknown function (DUF559) K07316 - 2.1.1.72 0.0001754 45.0
PYH2_k127_9077103_2 3-oxoacid CoA-transferase, B subunit K01029 GO:0001666,GO:0006950,GO:0008150,GO:0009628,GO:0036293,GO:0050896,GO:0070482 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000001531 253.0
PYH2_k127_9077103_3 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000003101 238.0
PYH2_k127_9077103_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000003182 200.0
PYH2_k127_9077103_5 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000001042 198.0
PYH2_k127_9077103_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000001756 181.0
PYH2_k127_9077103_7 Mo-molybdopterin cofactor metabolic process K02379,K03750,K03752,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000000000000000000000000000007854 181.0
PYH2_k127_9077103_8 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000302 175.0
PYH2_k127_9077103_9 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000339 164.0
PYH2_k127_9178004_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 374.0
PYH2_k127_9178004_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000111 103.0
PYH2_k127_9178004_2 PFAM regulatory protein TetR - - - 0.000002343 51.0
PYH2_k127_9216392_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004831 558.0
PYH2_k127_9216392_1 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 523.0
PYH2_k127_9216392_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 392.0
PYH2_k127_9216392_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000001643 241.0
PYH2_k127_9216392_4 CoA-transferase family III K08298 - 2.8.3.21 0.0009593 44.0
PYH2_k127_9260921_0 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 311.0
PYH2_k127_9260921_1 4Fe-4S binding domain - - - 0.00000000000000000000000006173 111.0
PYH2_k127_9288730_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001908 168.0
PYH2_k127_9301369_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000001626 237.0
PYH2_k127_93464_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 5.425e-309 971.0
PYH2_k127_93464_1 Domain of unknown function (DUF4131) K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 567.0
PYH2_k127_93464_10 Polysaccharide biosynthesis C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001259 282.0
PYH2_k127_93464_11 COG2015, Alkyl sulfatase and related hydrolases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009295 266.0
PYH2_k127_93464_12 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000549 246.0
PYH2_k127_93464_13 - - - - 0.000000000000000000000000000000000000000000000000000000000004863 217.0
PYH2_k127_93464_14 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000001743 203.0
PYH2_k127_93464_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.00000000000000000000000000000000000000000000000002947 185.0
PYH2_k127_93464_16 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000002162 181.0
PYH2_k127_93464_17 PAC2 family - - - 0.0000000000000000000000000000000000000000000003506 177.0
PYH2_k127_93464_18 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000001355 183.0
PYH2_k127_93464_19 RDD family - - - 0.0000000000000000000000000000000000009765 145.0
PYH2_k127_93464_2 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 539.0
PYH2_k127_93464_20 - - - - 0.000000000000000000000000000007768 128.0
PYH2_k127_93464_21 Helix-hairpin-helix motif K02237 - - 0.00000000000000000000000001023 116.0
PYH2_k127_93464_22 PspC domain - - - 0.00000000000000000002054 96.0
PYH2_k127_93464_23 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000008532 93.0
PYH2_k127_93464_24 HicB family K18843 - - 0.00000000000000001685 87.0
PYH2_k127_93464_25 - - - - 0.00000000003128 64.0
PYH2_k127_93464_27 membrane - - - 0.0000000003878 70.0
PYH2_k127_93464_3 E3 Ubiquitin ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007783 427.0
PYH2_k127_93464_4 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 372.0
PYH2_k127_93464_5 Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 355.0
PYH2_k127_93464_6 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007458 305.0
PYH2_k127_93464_7 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 299.0
PYH2_k127_93464_8 PFAM Thiolase, C-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006543 297.0
PYH2_k127_93464_9 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001062 286.0
PYH2_k127_949584_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 1.236e-209 677.0
PYH2_k127_949584_1 NADH flavin oxidoreductase NADH oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009914 464.0
PYH2_k127_949584_10 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000128 96.0
PYH2_k127_949584_2 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001815 280.0
PYH2_k127_949584_3 COG2041 Sulfite oxidase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
PYH2_k127_949584_4 helix_turn_helix, cAMP Regulatory protein K21564 - - 0.00000000000000000000000000000000000000000000000000000000000002709 222.0
PYH2_k127_949584_5 Transcriptional regulatory protein, C terminal K07667 - - 0.00000000000000000000000000000000000000000000000000000001223 205.0
PYH2_k127_949584_6 Cupin domain protein - - - 0.0000000000000000000000000000000000000001626 152.0
PYH2_k127_949584_7 - - - - 0.0000000000000000000000000000421 118.0
PYH2_k127_949584_8 NifU-like domain - - - 0.00000000000000000000000006428 108.0
PYH2_k127_949584_9 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000008267 111.0
PYH2_k127_975315_0 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 575.0
PYH2_k127_975315_1 PFAM aldo keto reductase K07079 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 441.0
PYH2_k127_975315_2 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002111 238.0
PYH2_k127_975315_3 Flavin reductase-like protein - - - 0.000000000000000000000000000000000006242 141.0
PYH2_k127_975315_4 - - - - 0.0000000005994 70.0
PYH2_k127_984296_0 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000004115 248.0
PYH2_k127_984296_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000707 207.0
PYH2_k127_984296_2 4Fe-4S dicluster domain K05796 - - 0.00000000000000000000000000001039 129.0
PYH2_k127_988393_0 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000006862 194.0
PYH2_k127_988393_1 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000001114 144.0