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Overview

ID MAG03205
Name PYH2_bin.64
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum JAUVQV01
Class JAUVQV01
Order
Family
Genus
Species
Assembly information
Completeness (%) 76.75
Contamination (%) 1.42
GC content (%) 64.0
N50 (bp) 7,679
Genome size (bp) 1,873,940

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1684

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1065447_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 6.729e-210 679.0
PYH2_k127_1065447_1 denitrification pathway K15876 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0044237,GO:0044425,GO:0045333,GO:0055114 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 581.0
PYH2_k127_1065447_2 Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002984 509.0
PYH2_k127_1065447_3 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 400.0
PYH2_k127_1065447_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005266 321.0
PYH2_k127_1065447_5 PFAM peptidase M16 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003389 295.0
PYH2_k127_1065447_6 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000001934 189.0
PYH2_k127_1065447_7 Glycosyltransferase family 87 - - - 0.000000000000000000000000000000000000000000000826 184.0
PYH2_k127_1065447_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000003436 147.0
PYH2_k127_1065447_9 - - - - 0.0000958 51.0
PYH2_k127_1136101_0 Belongs to the glycosyl hydrolase 57 family K22451 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 488.0
PYH2_k127_1136101_1 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 436.0
PYH2_k127_1136101_2 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 355.0
PYH2_k127_1136101_3 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000152 184.0
PYH2_k127_1136101_4 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000000004171 93.0
PYH2_k127_1136101_5 - - - - 0.0000001226 63.0
PYH2_k127_1200458_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 8.357e-297 947.0
PYH2_k127_1200458_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K10535 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006091,GO:0006807,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015975,GO:0015980,GO:0016491,GO:0016661,GO:0016663,GO:0019329,GO:0019331,GO:0034641,GO:0042597,GO:0044237,GO:0044281,GO:0044464,GO:0045333,GO:0047991,GO:0055114 1.7.2.6 5.965e-199 627.0
PYH2_k127_1200458_10 efflux transmembrane transporter activity K03296,K12340 - - 0.0000000000000000000000000008705 128.0
PYH2_k127_1200458_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000003725 117.0
PYH2_k127_1200458_2 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 506.0
PYH2_k127_1200458_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 444.0
PYH2_k127_1200458_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 422.0
PYH2_k127_1200458_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 342.0
PYH2_k127_1200458_6 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 308.0
PYH2_k127_1200458_7 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000001243 225.0
PYH2_k127_1200458_8 Cupin superfamily (DUF985) K09705 - - 0.000000000000000000000000000000000000000000000000000000000392 210.0
PYH2_k127_1200458_9 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000002016 210.0
PYH2_k127_1231131_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 396.0
PYH2_k127_1231131_1 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007506 320.0
PYH2_k127_1231131_2 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000008094 175.0
PYH2_k127_1231131_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000002219 126.0
PYH2_k127_1231131_4 OstA-like protein K09774 - - 0.000000000002227 79.0
PYH2_k127_1231131_5 lipopolysaccharide transmembrane transporter activity K09774,K11719 - - 0.0000002489 60.0
PYH2_k127_1234518_0 Glutamine amidotransferases class-II K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 583.0
PYH2_k127_1234518_1 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007918 289.0
PYH2_k127_1234518_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000001151 145.0
PYH2_k127_1234518_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000006523 62.0
PYH2_k127_1245731_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 5.32e-274 855.0
PYH2_k127_1245731_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 582.0
PYH2_k127_1245731_2 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 298.0
PYH2_k127_1245731_3 Pterin binding enzyme K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000004033 264.0
PYH2_k127_1245731_4 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000003039 238.0
PYH2_k127_1245731_5 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000105 108.0
PYH2_k127_1245731_6 PFAM YbbR family protein - - - 0.000000000000002027 87.0
PYH2_k127_1249417_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006877 568.0
PYH2_k127_1249417_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 299.0
PYH2_k127_1252339_0 Alpha amylase, catalytic domain - - - 1.043e-256 814.0
PYH2_k127_1252339_1 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 418.0
PYH2_k127_1252339_2 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 396.0
PYH2_k127_1252339_3 PFAM ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007368 382.0
PYH2_k127_1252339_4 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 365.0
PYH2_k127_1252339_5 CARDB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 296.0
PYH2_k127_1252339_6 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 305.0
PYH2_k127_1252339_7 - - - - 0.00000000000000004092 95.0
PYH2_k127_1264530_0 PFAM Phosphoglycerate mutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 482.0
PYH2_k127_1264530_1 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009051 478.0
PYH2_k127_1264530_2 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003381 399.0
PYH2_k127_1264530_3 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000004595 239.0
PYH2_k127_1264530_5 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000001626 90.0
PYH2_k127_1264844_0 DRTGG domain protein K06873 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001848 269.0
PYH2_k127_1264844_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000005408 244.0
PYH2_k127_1264844_2 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000005345 223.0
PYH2_k127_1264844_3 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000001832 213.0
PYH2_k127_1264844_4 Thioredoxin domain - - - 0.00000000000000336 77.0
PYH2_k127_1264844_5 TIGRFAM glutaredoxin-like domain protein - - - 0.000000000001654 78.0
PYH2_k127_1277142_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 8.699e-243 764.0
PYH2_k127_1277142_1 potassium uptake protein TrkH K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009847 547.0
PYH2_k127_1277142_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 421.0
PYH2_k127_1277142_3 Polyprenyl synthetase K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004383 286.0
PYH2_k127_1277142_4 ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 264.0
PYH2_k127_1277142_5 TrkA-N domain K03499 - - 0.00000000000000000000000000000000000000000000000000001277 197.0
PYH2_k127_1277142_6 domain protein K03499 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000007693 185.0
PYH2_k127_1277142_7 - - - - 0.000000000000000000000006338 117.0
PYH2_k127_1277142_8 Molybdenum cofactor synthesis domain - - - 0.0000000000000000003739 93.0
PYH2_k127_1277142_9 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.000000000000004033 79.0
PYH2_k127_1277967_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 398.0
PYH2_k127_1277967_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000001157 273.0
PYH2_k127_1277967_2 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000855 232.0
PYH2_k127_1277967_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000005104 125.0
PYH2_k127_1277967_4 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000001394 126.0
PYH2_k127_1347122_0 Nickel-dependent hydrogenase - - - 3.839e-205 646.0
PYH2_k127_1347122_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 336.0
PYH2_k127_1347122_2 PFAM NLP P60 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004357 267.0
PYH2_k127_1347122_3 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000001697 207.0
PYH2_k127_1347122_4 HI0933 family K07007 - - 0.0000000000000000000000000000000000005642 146.0
PYH2_k127_1347122_5 maturation protease K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.000000000000000000000000006285 115.0
PYH2_k127_1365062_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005968 243.0
PYH2_k127_1365062_1 oligosaccharyl transferase activity - - - 0.00000000121 64.0
PYH2_k127_1365062_2 lipolytic protein G-D-S-L family K20306 - - 0.00000001486 66.0
PYH2_k127_1398998_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 8.663e-241 769.0
PYH2_k127_1398998_1 TIGRFAM DNA protecting protein DprA K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003403 289.0
PYH2_k127_1398998_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 270.0
PYH2_k127_1398998_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
PYH2_k127_1398998_4 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.00000000000000000000000000000000003428 149.0
PYH2_k127_1398998_5 Belongs to the Smg family K03747 - - 0.0000000001282 70.0
PYH2_k127_1466648_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 311.0
PYH2_k127_1466648_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 299.0
PYH2_k127_1466648_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000001077 220.0
PYH2_k127_1466648_3 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000002599 151.0
PYH2_k127_1497193_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007112 352.0
PYH2_k127_1497193_1 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006472 271.0
PYH2_k127_1497193_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000002777 237.0
PYH2_k127_1497193_3 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000001356 204.0
PYH2_k127_1497193_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000003918 77.0
PYH2_k127_1498938_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 611.0
PYH2_k127_1498938_1 biotin carboxylase activity K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004833 586.0
PYH2_k127_1498938_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 437.0
PYH2_k127_1498938_3 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 404.0
PYH2_k127_1498938_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000001866 156.0
PYH2_k127_1498938_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000008143 156.0
PYH2_k127_1498938_6 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 GO:0003674,GO:0003824,GO:0003989,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009305,GO:0009987,GO:0016049,GO:0016053,GO:0016421,GO:0016874,GO:0016885,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 - 0.0000000000000000000000000000000000008948 145.0
PYH2_k127_1498938_7 PFAM biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000006319 106.0
PYH2_k127_1498938_8 PFAM Metallopeptidase family M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000002902 97.0
PYH2_k127_1532907_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 346.0
PYH2_k127_1532907_1 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000326 251.0
PYH2_k127_1532907_2 oligosaccharyl transferase activity - - - 0.000000000000000002202 99.0
PYH2_k127_1567123_0 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 453.0
PYH2_k127_1567123_1 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 394.0
PYH2_k127_1567123_2 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000005715 241.0
PYH2_k127_1567123_3 Membrane - - - 0.00000000000000000000000000000000000000000000000000001964 191.0
PYH2_k127_1567123_4 Cupin domain - - - 0.0000000000000000000000000000001047 126.0
PYH2_k127_1573683_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000001544 127.0
PYH2_k127_1573683_1 lipolytic protein G-D-S-L family - - - 0.00000001216 67.0
PYH2_k127_1573683_2 MORN repeat variant - - - 0.00000002563 63.0
PYH2_k127_1630923_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 346.0
PYH2_k127_1630923_1 Haloacid dehalogenase-like hydrolase K07025 - - 0.0000000000000000000000000000000000000000000000003339 186.0
PYH2_k127_1630923_2 nucleoside recognition domain protein - - - 0.000000000000000000000000000001312 128.0
PYH2_k127_1630923_3 Nucleoside recognition - - - 0.000000000000000000006963 103.0
PYH2_k127_1630923_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000001 70.0
PYH2_k127_1639778_0 HI0933-like protein K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 484.0
PYH2_k127_1639778_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003978 393.0
PYH2_k127_1639778_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007137 279.0
PYH2_k127_1639778_3 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000002564 161.0
PYH2_k127_1639778_4 Phosphoribosyl transferase domain K00759 - 2.4.2.7 0.000000000000000001626 85.0
PYH2_k127_1639778_5 - - - - 0.0006963 48.0
PYH2_k127_1643723_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002706 283.0
PYH2_k127_1643723_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 0.000000000000000000000000000000000000000000000000000000000000003776 219.0
PYH2_k127_1666470_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 536.0
PYH2_k127_1666470_1 Ceramidase - - - 0.0000000000000000000000000000000000000000000000000000001316 206.0
PYH2_k127_1666470_2 DinB family - - - 0.000000000000000000000000000000000000000000000004044 180.0
PYH2_k127_1666470_3 chaperone-mediated protein folding - - - 0.00000000000000000000000009336 123.0
PYH2_k127_1666470_4 oligosaccharyl transferase activity - - - 0.0000000000000000000000001216 123.0
PYH2_k127_1666470_6 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000004861 81.0
PYH2_k127_1666470_7 PKD domain - - - 0.0000000004882 72.0
PYH2_k127_1694554_0 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000016 195.0
PYH2_k127_1694554_1 polysaccharide export protein K01991 - - 0.000000000000000000000003912 109.0
PYH2_k127_172416_0 cytochrome C - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 357.0
PYH2_k127_172416_1 - - - - 0.000000000000000000000000000005606 139.0
PYH2_k127_172416_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000008395 81.0
PYH2_k127_1751365_0 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008696 528.0
PYH2_k127_1751365_1 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 313.0
PYH2_k127_1751365_2 peptidase dimerisation domain protein K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000001582 227.0
PYH2_k127_1751365_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000002934 193.0
PYH2_k127_1751365_4 DinB superfamily - - - 0.000000000000000000000000000000000000000000002426 170.0
PYH2_k127_1790676_0 Threonine synthase K01733 - 4.2.3.1 2.613e-197 625.0
PYH2_k127_1790676_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006656 441.0
PYH2_k127_1790676_2 alginic acid biosynthetic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 371.0
PYH2_k127_1790676_3 chaperone-mediated protein folding - - - 0.00000000000000000000000000000005858 143.0
PYH2_k127_1834866_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000005177 184.0
PYH2_k127_1834866_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000001979 166.0
PYH2_k127_1882884_0 HflC and HflK could encode or regulate a protease K04088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 384.0
PYH2_k127_1882884_1 Bacterial sugar transferase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 372.0
PYH2_k127_1882884_2 Sensor diguanylate cyclase, PAS domain-containing - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 314.0
PYH2_k127_1882884_3 Glycosyl transferases group 1 K12989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001244 296.0
PYH2_k127_1882884_4 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000000000004416 219.0
PYH2_k127_1882884_5 prohibitin homologues K04087 - - 0.000001183 52.0
PYH2_k127_1925358_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 520.0
PYH2_k127_1925358_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 331.0
PYH2_k127_1925358_2 PAS domain K13598 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 308.0
PYH2_k127_1925358_3 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003705 258.0
PYH2_k127_1925358_4 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000006012 244.0
PYH2_k127_1925358_5 Methylene-tetrahydrofolate reductase C terminal - - - 0.0002986 51.0
PYH2_k127_1929096_0 PFAM PhoH-like protein K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 450.0
PYH2_k127_1929096_1 Protein of unknown function DUF58 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001262 280.0
PYH2_k127_1929096_2 O-methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000009313 208.0
PYH2_k127_1929096_3 Aerotolerance regulator N-terminal - - - 0.00000000000000000000000000000000000000000000000005213 201.0
PYH2_k127_1971806_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 412.0
PYH2_k127_1971806_1 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006878 280.0
PYH2_k127_1971806_2 transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000009801 241.0
PYH2_k127_1971806_3 Uncharacterized protein family, UPF0114 - - - 0.000000000000000000000000000000000000000005148 160.0
PYH2_k127_1971806_4 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000008507 78.0
PYH2_k127_1979876_0 SMART Elongator protein 3 MiaB NifB K22227 - - 6.362e-207 646.0
PYH2_k127_1979876_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 413.0
PYH2_k127_1979876_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000002116 288.0
PYH2_k127_1979876_3 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.00000000000000000000000002361 111.0
PYH2_k127_200948_0 TraB family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002742 531.0
PYH2_k127_200948_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 412.0
PYH2_k127_200948_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002364 273.0
PYH2_k127_2029120_0 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 398.0
PYH2_k127_2029120_1 Deoxyhypusine synthase K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 348.0
PYH2_k127_2029120_10 isopentenyl-diphosphate delta-isomerase activity K00949,K01823 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.6.2,5.3.3.2 0.00000000000000000000000000000000000000000000002581 175.0
PYH2_k127_2029120_11 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000009932 178.0
PYH2_k127_2029120_12 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000003901 163.0
PYH2_k127_2029120_13 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000006567 100.0
PYH2_k127_2029120_14 - - - - 0.000000003289 65.0
PYH2_k127_2029120_15 Arginase family K01480 - 3.5.3.11 0.0000001066 62.0
PYH2_k127_2029120_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 310.0
PYH2_k127_2029120_3 Protein of unknown function (DUF554) K07150 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 301.0
PYH2_k127_2029120_4 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 302.0
PYH2_k127_2029120_5 PFAM HhH-GPD family protein K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005158 270.0
PYH2_k127_2029120_6 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004428 255.0
PYH2_k127_2029120_7 ResB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000005216 243.0
PYH2_k127_2029120_8 thiolester hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000004877 203.0
PYH2_k127_2029120_9 phosphoribosyltransferase K07100 - - 0.00000000000000000000000000000000000000000000000003654 189.0
PYH2_k127_204386_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.085e-218 692.0
PYH2_k127_204386_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 2.195e-209 659.0
PYH2_k127_204386_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000007175 173.0
PYH2_k127_2080116_0 CAAX protease self-immunity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005782 261.0
PYH2_k127_2080116_1 SRP54-type protein, GTPase domain K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000001502 188.0
PYH2_k127_2080116_2 - - - - 0.0000000000000000000000000000000000003938 155.0
PYH2_k127_2080116_3 Pkd domain containing protein - - - 0.000000000000000000000002315 117.0
PYH2_k127_2080116_4 Parallel beta-helix repeats - - - 0.000000005758 69.0
PYH2_k127_2080116_5 - - - - 0.00005117 55.0
PYH2_k127_2086426_0 Bacterial transferase hexapeptide (six repeats) K00633,K00661 - 2.3.1.18,2.3.1.79 0.000000000000000000000000000000000000000000000000000228 195.0
PYH2_k127_2086426_1 Uracil-DNA glycosylase, family 4 K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000002069 179.0
PYH2_k127_2086426_2 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000003006 141.0
PYH2_k127_2086426_3 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000001932 136.0
PYH2_k127_2086426_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000007687 108.0
PYH2_k127_2086426_5 - - - - 0.00000004358 66.0
PYH2_k127_2086426_6 PA14 domain - - - 0.000009667 55.0
PYH2_k127_2104131_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002151 293.0
PYH2_k127_2104131_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000003954 198.0
PYH2_k127_2104131_2 Phospholipase K07001 - - 0.0000000000000001337 91.0
PYH2_k127_2104131_3 PFAM CheW domain protein K03408 - - 0.00000006605 64.0
PYH2_k127_2104131_4 Redoxin - - - 0.0003288 48.0
PYH2_k127_2104819_0 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 326.0
PYH2_k127_2104819_1 beta Propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 302.0
PYH2_k127_2104819_2 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 287.0
PYH2_k127_2104819_3 Cellulase (glycosyl hydrolase family 5) K01179 - 3.2.1.4 0.000000000000000000000000000000000002296 150.0
PYH2_k127_2104819_4 gluconolactonase activity K07214 - - 0.00000000000005308 83.0
PYH2_k127_2122872_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004029 234.0
PYH2_k127_2122872_1 Hep Hag repeat protein - - - 0.00000000000000000000000000000000000000002487 164.0
PYH2_k127_2122872_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000002228 142.0
PYH2_k127_2122872_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000002692 60.0
PYH2_k127_2159425_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.519e-246 781.0
PYH2_k127_2159425_1 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 581.0
PYH2_k127_2159425_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 520.0
PYH2_k127_2159425_3 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001293 278.0
PYH2_k127_2159425_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008151 285.0
PYH2_k127_2159425_5 HEAT repeats - - - 0.000000000000000000000000000000000000000000001633 185.0
PYH2_k127_2159425_6 Branched-chain amino acid transport K01995 - - 0.0000000000000000000000000000000000000001153 154.0
PYH2_k127_2163092_0 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000000000006183 216.0
PYH2_k127_2163092_1 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000001843 180.0
PYH2_k127_2163092_2 Polysaccharide biosynthesis protein - - - 0.0004087 50.0
PYH2_k127_2164555_0 Domain of unknown function (DUF4372) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 528.0
PYH2_k127_2164555_1 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000000006582 176.0
PYH2_k127_2164555_2 Histidine kinase K03406,K13487 - - 0.00000000000000000000000000000000000000001031 173.0
PYH2_k127_2164555_3 - - - - 0.0000000000000000000000000000001644 126.0
PYH2_k127_2164555_4 Regulatory protein, FmdB family - - - 0.000001046 53.0
PYH2_k127_2203584_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003639 467.0
PYH2_k127_2203584_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 445.0
PYH2_k127_2203584_2 NIL - - - 0.0000000000000000000000000000000000000000001313 163.0
PYH2_k127_2203584_3 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000001203 153.0
PYH2_k127_2203584_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000254 130.0
PYH2_k127_2203584_5 addiction module antidote protein HigA K21498 - - 0.00000000009996 62.0
PYH2_k127_2218186_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 6.589e-307 958.0
PYH2_k127_2218186_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 524.0
PYH2_k127_2218186_2 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 514.0
PYH2_k127_2218186_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000996 306.0
PYH2_k127_2218186_4 PFAM ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006878 293.0
PYH2_k127_2218186_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.00000000000000000000000000000000000000000000000000000000006199 214.0
PYH2_k127_2218186_6 Outer membrane protein (OmpH-like) K06142 - - 0.0000000000000000000000006282 111.0
PYH2_k127_2218186_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000139 52.0
PYH2_k127_2218186_8 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0001986 54.0
PYH2_k127_2228967_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002652 475.0
PYH2_k127_2228967_1 Large family of predicted nucleotide-binding domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
PYH2_k127_2228967_2 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000205 241.0
PYH2_k127_2228967_3 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000009862 192.0
PYH2_k127_2228967_4 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.0000000000000000000000000000000000000000000000000009533 194.0
PYH2_k127_2228967_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000514 78.0
PYH2_k127_22431_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 413.0
PYH2_k127_22431_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000001942 198.0
PYH2_k127_22431_2 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000001063 74.0
PYH2_k127_2286093_0 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000003005 220.0
PYH2_k127_2286093_1 Putative cyclase K07130 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000004525 192.0
PYH2_k127_2286093_2 Biopolymer transport protein ExbD/TolR K03559,K03560 - - 0.00000000000000000004083 102.0
PYH2_k127_2374546_0 Aminotransferase class I and II K10206,K14261 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 488.0
PYH2_k127_2374546_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 389.0
PYH2_k127_2374546_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005655 289.0
PYH2_k127_2374546_3 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007001 280.0
PYH2_k127_2374546_4 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000001431 269.0
PYH2_k127_2374546_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000002488 211.0
PYH2_k127_2374546_6 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000003561 149.0
PYH2_k127_2374546_7 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.00000000000000000000000000000000000005913 155.0
PYH2_k127_2397764_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006443 438.0
PYH2_k127_2397764_1 protein secretion K02460 - - 0.000000000000000000000000000000000000001155 161.0
PYH2_k127_2397764_2 Prokaryotic N-terminal methylation motif K02459 - - 0.000000395 61.0
PYH2_k127_2397764_3 Pilus assembly protein K02461,K02662 - - 0.0000305 55.0
PYH2_k127_2397764_4 general secretion pathway protein K02458 - - 0.0003791 49.0
PYH2_k127_2491290_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.455e-226 723.0
PYH2_k127_2491290_1 PFAM phosphoesterase, RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000002329 191.0
PYH2_k127_2491290_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000001871 109.0
PYH2_k127_2491290_3 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000006651 96.0
PYH2_k127_2491290_4 ncRNA processing K07590,K07742 - - 0.00003046 49.0
PYH2_k127_2491878_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 567.0
PYH2_k127_2491878_1 3-isopropylmalate dehydrogenase activity K00052 GO:0000287,GO:0003674,GO:0003824,GO:0003862,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009267,GO:0009605,GO:0009987,GO:0009991,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0030145,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0034198,GO:0042594,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0071496,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1990928 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 407.0
PYH2_k127_2491878_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000001314 194.0
PYH2_k127_2491878_3 Cytochrome C biogenesis protein - - - 0.000000000000000000000000000000000000000000522 172.0
PYH2_k127_2491878_4 Protein of unknown function (DUF1573) - - - 0.0000000001304 72.0
PYH2_k127_2505656_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 1.082e-283 897.0
PYH2_k127_2505656_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.046e-273 860.0
PYH2_k127_2505656_10 - - - - 0.00000000000006248 82.0
PYH2_k127_2505656_2 BPG-independent PGAM N-terminus (iPGM_N) K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 552.0
PYH2_k127_2505656_3 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 486.0
PYH2_k127_2505656_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 368.0
PYH2_k127_2505656_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 330.0
PYH2_k127_2505656_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000795 209.0
PYH2_k127_2505656_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000001487 124.0
PYH2_k127_2505656_8 Methyltransferase domain protein - - - 0.0000000000000000000002229 112.0
PYH2_k127_2505656_9 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.0000000000000000001616 94.0
PYH2_k127_2507542_0 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009939 340.0
PYH2_k127_2507542_1 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000000000008845 195.0
PYH2_k127_2521397_0 anaerobic respiration - - - 0.00000000000000000000000000000000000000000000000000000000000003244 231.0
PYH2_k127_2521397_1 MotA TolQ ExbB proton channel family K03561 - - 0.000000000000000000000000000000000000000000000000000007027 197.0
PYH2_k127_2521397_2 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000003779 141.0
PYH2_k127_2521397_3 biopolymer transport protein K03560 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015833,GO:0015893,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032153,GO:0042221,GO:0042493,GO:0042886,GO:0042891,GO:0043213,GO:0044425,GO:0044459,GO:0044464,GO:0050896,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000001305 86.0
PYH2_k127_2521397_4 denitrification pathway - - - 0.000000000000001017 88.0
PYH2_k127_2521397_6 ExbD TolR K03559 - - 0.00000001712 61.0
PYH2_k127_2530306_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 589.0
PYH2_k127_2530306_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621,K21576,K21577 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.21.4.2,1.21.4.3,1.21.4.4,2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 388.0
PYH2_k127_2530306_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 387.0
PYH2_k127_2530306_3 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000248 107.0
PYH2_k127_2530306_4 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000002078 80.0
PYH2_k127_2533955_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.05e-280 880.0
PYH2_k127_2533955_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000008059 171.0
PYH2_k127_2533955_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002014 132.0
PYH2_k127_2535584_0 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 469.0
PYH2_k127_2535584_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 420.0
PYH2_k127_2535584_2 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 408.0
PYH2_k127_2546481_0 Phosphoglycerate kinase K00927 - 2.7.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 486.0
PYH2_k127_2546481_1 Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006732 458.0
PYH2_k127_2546481_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 297.0
PYH2_k127_2546481_3 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000003829 243.0
PYH2_k127_2546481_4 PFAM Preprotein translocase SecG subunit K03075 - - 0.000000000000000004556 85.0
PYH2_k127_2603384_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 498.0
PYH2_k127_2603384_1 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 355.0
PYH2_k127_2603384_2 COG3959 Transketolase, N-terminal subunit K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 316.0
PYH2_k127_2603384_3 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004624 274.0
PYH2_k127_2615882_0 Belongs to the DegT DnrJ EryC1 family K13017 - 2.6.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 468.0
PYH2_k127_2615882_1 Histidine kinase - - - 0.0000001974 63.0
PYH2_k127_2615882_2 heat shock protein binding - - - 0.0000004488 63.0
PYH2_k127_2648214_0 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008566 361.0
PYH2_k127_2648214_1 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 299.0
PYH2_k127_2648214_2 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000024 287.0
PYH2_k127_2648214_3 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009589 255.0
PYH2_k127_2648214_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000002083 173.0
PYH2_k127_2662539_0 HI0933-like protein K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008344 419.0
PYH2_k127_2662539_1 self proteolysis K01081,K01119,K01286,K01992,K07258 - 3.1.3.5,3.1.3.6,3.1.4.16,3.4.16.4 0.0000000004282 74.0
PYH2_k127_2662539_2 type IV pilus modification protein PilV K02458,K02671 - - 0.00000001459 64.0
PYH2_k127_2662539_3 Type II transport protein GspH K08084 - - 0.00005061 52.0
PYH2_k127_2662539_4 Type IV Pilus-assembly protein W K02672 - - 0.0005369 54.0
PYH2_k127_2668694_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 9.782e-267 831.0
PYH2_k127_2668694_1 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003349 265.0
PYH2_k127_2668694_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002998 282.0
PYH2_k127_2668694_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000006449 187.0
PYH2_k127_2668694_4 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.0000000000007309 70.0
PYH2_k127_2675108_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 364.0
PYH2_k127_2675108_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004596 362.0
PYH2_k127_2675108_2 - - - - 0.0000000000000000000000000000000000000000000000000000000001369 209.0
PYH2_k127_2675108_4 Protein of unknown function (DUF2442) - - - 0.00000000000000008377 83.0
PYH2_k127_2675108_5 Helix-turn-helix XRE-family like proteins K21498 - - 0.00000000000000008566 81.0
PYH2_k127_2675108_6 ABC transporter K01995 - - 0.0000000000007459 69.0
PYH2_k127_2675108_7 Transposase DDE domain group 1 - - - 0.000000001141 64.0
PYH2_k127_2730224_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009818 554.0
PYH2_k127_2730224_1 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000000404 147.0
PYH2_k127_2730224_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000004071 165.0
PYH2_k127_2777713_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 507.0
PYH2_k127_2777713_1 Flavin containing amine oxidoreductase K09516 - 1.3.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 424.0
PYH2_k127_2777713_2 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 329.0
PYH2_k127_2777713_3 Beta-ketoacyl synthase, C-terminal domain K00647 - 2.3.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 328.0
PYH2_k127_2777713_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000002103 96.0
PYH2_k127_2777713_6 Phosphopantetheine attachment site - - - 0.000000000000000005298 92.0
PYH2_k127_2777713_7 Esterase PHB depolymerase - - - 0.000000000004582 76.0
PYH2_k127_2836078_0 Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 373.0
PYH2_k127_2836078_1 - - - - 0.000000000000000000000000005251 128.0
PYH2_k127_2866706_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 491.0
PYH2_k127_2866706_1 RnfC Barrel sandwich hybrid domain K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 470.0
PYH2_k127_2866706_10 Putative RNA methylase family UPF0020 K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000005617 198.0
PYH2_k127_2866706_11 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000852 185.0
PYH2_k127_2866706_12 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000003866 117.0
PYH2_k127_2866706_13 Part of a membrane complex involved in electron transport K03612 - - 0.0000000000000000000000001864 113.0
PYH2_k127_2866706_14 peptidyl-tyrosine sulfation - - - 0.000000000003413 70.0
PYH2_k127_2866706_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002495 462.0
PYH2_k127_2866706_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 408.0
PYH2_k127_2866706_4 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 302.0
PYH2_k127_2866706_5 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004562 289.0
PYH2_k127_2866706_6 electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001538 269.0
PYH2_k127_2866706_7 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000008899 257.0
PYH2_k127_2866706_8 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000007153 247.0
PYH2_k127_2866706_9 electron transport chain K02560,K03613,K10773 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0044464,GO:0055114,GO:0071944 2.3.1.243,4.2.99.18 0.00000000000000000000000000000000000000000000000000000003051 211.0
PYH2_k127_2924622_0 SecA preprotein cross-linking domain K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 514.0
PYH2_k127_2924622_1 Tetratricopeptide repeat - - - 0.000000000000005657 90.0
PYH2_k127_2933814_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005819 369.0
PYH2_k127_2933814_1 spermidine synthase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 376.0
PYH2_k127_2933814_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000005667 194.0
PYH2_k127_2933814_3 - - - - 0.000000000000000000000000001468 117.0
PYH2_k127_2933814_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0000000000000000000003101 98.0
PYH2_k127_2933814_5 TIGRFAM Por secretion system C-terminal sorting domain - - - 0.000009552 57.0
PYH2_k127_2985376_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 404.0
PYH2_k127_2985376_1 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 376.0
PYH2_k127_2989316_0 arylsulfatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009445 280.0
PYH2_k127_2989316_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000001455 65.0
PYH2_k127_2993137_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1054.0
PYH2_k127_2993137_1 PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 462.0
PYH2_k127_2993137_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 448.0
PYH2_k127_2993137_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 431.0
PYH2_k127_2993137_4 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000365 219.0
PYH2_k127_2993137_5 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000001386 222.0
PYH2_k127_2993137_6 Bacterial membrane protein YfhO - - - 0.000000000000000000000000000000000000000000000005135 198.0
PYH2_k127_2993137_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000002762 89.0
PYH2_k127_2993137_8 Class III cytochrome C family - - - 0.0003158 49.0
PYH2_k127_3028004_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 574.0
PYH2_k127_3028004_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 370.0
PYH2_k127_3028004_2 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.000000000000000000000000000000000000000000000000000000000003927 218.0
PYH2_k127_3050541_0 Nad-dependent epimerase dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000005433 234.0
PYH2_k127_3050541_1 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000006789 184.0
PYH2_k127_3050541_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000003717 94.0
PYH2_k127_3050541_3 polysaccharide biosynthetic process - - - 0.000005903 57.0
PYH2_k127_3053517_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 2.183e-242 769.0
PYH2_k127_3053517_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004357 437.0
PYH2_k127_3053517_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 392.0
PYH2_k127_3053517_3 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 347.0
PYH2_k127_3053517_4 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 345.0
PYH2_k127_3053517_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 298.0
PYH2_k127_3053517_6 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002502 272.0
PYH2_k127_3053517_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000002434 237.0
PYH2_k127_3053517_8 Protein of unknown function DUF58 - - - 0.0000000000000000000000479 113.0
PYH2_k127_3061022_0 Restriction endonuclease - - - 0.0000000000000000000000000000000000000000000000000001299 197.0
PYH2_k127_3061022_1 KOW (Kyprides, Ouzounis, Woese) motif. K05785 - - 0.0000000000000000005895 94.0
PYH2_k127_3061022_2 PPIC-type PPIASE domain - - - 0.000000000000000248 87.0
PYH2_k127_3091010_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000001077 220.0
PYH2_k127_3091010_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000001311 151.0
PYH2_k127_3091010_2 lipolytic protein G-D-S-L family K20306 - - 0.00000000000000000000002084 113.0
PYH2_k127_3091010_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0001562 45.0
PYH2_k127_3097027_0 GTP-binding protein TypA K06207 - - 1.291e-227 715.0
PYH2_k127_3097027_1 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 432.0
PYH2_k127_3097027_2 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009893 252.0
PYH2_k127_3097027_3 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000008524 202.0
PYH2_k127_3097027_4 Iron-sulfur cluster binding protein - - - 0.000000000000000000000000000003241 122.0
PYH2_k127_3173819_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 8.082e-302 938.0
PYH2_k127_3173819_1 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 580.0
PYH2_k127_3173819_10 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000001569 135.0
PYH2_k127_3173819_11 HAF family - - - 0.000000000000007422 89.0
PYH2_k127_3173819_12 PFAM Tetratricopeptide repeat - - - 0.000005833 55.0
PYH2_k127_3173819_2 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 429.0
PYH2_k127_3173819_3 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 398.0
PYH2_k127_3173819_4 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 312.0
PYH2_k127_3173819_5 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003222 270.0
PYH2_k127_3173819_6 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000164 247.0
PYH2_k127_3173819_7 denitrification pathway - - - 0.00000000000000000000000000000000000000000000006326 188.0
PYH2_k127_3173819_8 metallopeptidase activity K01637 - 4.1.3.1 0.0000000000000000000000000000000000000000004841 179.0
PYH2_k127_3173819_9 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000002203 165.0
PYH2_k127_3205218_0 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000000000000000000000000000000000000007571 237.0
PYH2_k127_3205218_1 - - - - 0.000000000000000000000000000000000000000000000000000000003485 212.0
PYH2_k127_3205218_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000003183 115.0
PYH2_k127_3205218_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00002879 53.0
PYH2_k127_3205218_4 iron ion homeostasis K03709,K04758 - - 0.0002177 44.0
PYH2_k127_3231306_0 PFAM Radical SAM K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 347.0
PYH2_k127_3231306_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000001835 220.0
PYH2_k127_3231306_2 RHS Repeat - - - 0.00000000000000000000000000000000000000000008934 172.0
PYH2_k127_3231306_3 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000000001745 170.0
PYH2_k127_3231306_4 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000001473 123.0
PYH2_k127_3244559_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 477.0
PYH2_k127_3244559_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003574 331.0
PYH2_k127_3244559_2 four-way junction helicase activity K03550 GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000000000000000005848 185.0
PYH2_k127_3244559_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.000000000000000000000000000000000000000000000000281 183.0
PYH2_k127_3244559_4 pfam php K01104 - 3.1.3.48 0.0000000000000000000000000000000000000000000000005685 187.0
PYH2_k127_3244559_5 Uncharacterised nucleotidyltransferase - - - 0.00000000000000000000000000000000000000002342 165.0
PYH2_k127_3244559_6 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000003686 156.0
PYH2_k127_3244559_7 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.00000004624 58.0
PYH2_k127_3267917_0 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 488.0
PYH2_k127_3267917_1 PFAM LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002796 281.0
PYH2_k127_3267917_2 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000000000000001611 223.0
PYH2_k127_3271580_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 601.0
PYH2_k127_3271580_1 PFAM Glycosyl transferase, family 2 K10012,K20534 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 347.0
PYH2_k127_3271580_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000001175 137.0
PYH2_k127_3271580_3 Iron-sulfur cluster-binding domain - - - 0.00009515 50.0
PYH2_k127_3326650_0 tRNA synthetases class I (W and Y) K01867 GO:0003674,GO:0003824,GO:0004812,GO:0004830,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006436,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 450.0
PYH2_k127_3326650_1 RecF/RecN/SMC N terminal domain K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 387.0
PYH2_k127_3326650_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000008675 207.0
PYH2_k127_3326650_3 Belongs to the pseudouridine synthase RsuA family K06178,K06182 - 5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000001094 196.0
PYH2_k127_3326650_4 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000001193 196.0
PYH2_k127_3326650_5 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000002641 173.0
PYH2_k127_3326650_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000006707 160.0
PYH2_k127_3326650_7 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000001602 108.0
PYH2_k127_3328057_0 Bacterial sugar transferase K03606 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 490.0
PYH2_k127_3328057_1 Glycosyltransferase Family 4 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 371.0
PYH2_k127_3328057_10 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 GO:0000966,GO:0000967,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000001005 123.0
PYH2_k127_3328057_11 sigma-54 factor interaction domain-containing protein K02667 - - 0.00000000000000001459 86.0
PYH2_k127_3328057_2 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005808 329.0
PYH2_k127_3328057_3 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 301.0
PYH2_k127_3328057_4 YceG-like family K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009115 265.0
PYH2_k127_3328057_5 Glycosyl transferase 4-like domain - - - 0.000000000000000000000000000000000000000000000000000000000007697 222.0
PYH2_k127_3328057_6 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000888 227.0
PYH2_k127_3328057_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000376 211.0
PYH2_k127_3328057_8 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000002553 164.0
PYH2_k127_3328057_9 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000001858 141.0
PYH2_k127_3333986_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 503.0
PYH2_k127_3333986_1 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000001065 152.0
PYH2_k127_3333986_2 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000005352 132.0
PYH2_k127_3333986_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.00000000000000000000000000257 121.0
PYH2_k127_3333986_4 Belongs to the ompA family K03640 GO:0005575,GO:0005623,GO:0008150,GO:0009279,GO:0009987,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031224,GO:0031230,GO:0031241,GO:0031246,GO:0031975,GO:0032153,GO:0044425,GO:0044462,GO:0044464,GO:0051301,GO:0071944,GO:0098552 - 0.00000000000000000003592 93.0
PYH2_k127_3338527_0 PFAM multicopper oxidase type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 552.0
PYH2_k127_3338527_1 PFAM Magnesium chelatase, ChlI subunit K07391 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002457 279.0
PYH2_k127_3338527_2 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008507 274.0
PYH2_k127_3338527_3 ATPase with chaperone activity K07391 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0042623,GO:0043170,GO:0044238,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.00002208 49.0
PYH2_k127_3346690_0 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 343.0
PYH2_k127_3346690_1 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 296.0
PYH2_k127_3346690_2 PFAM Methyltransferase domain K18827 - 2.1.1.294,2.7.1.181 0.0000000000000000000000000000000000000000000000000000000002735 210.0
PYH2_k127_3363529_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 548.0
PYH2_k127_3363529_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 473.0
PYH2_k127_3363529_2 Oxidoreductase FAD-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008541 416.0
PYH2_k127_3363529_3 coenzyme F420 hydrogenase activity K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 394.0
PYH2_k127_3363529_4 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000001306 249.0
PYH2_k127_3363529_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000007318 185.0
PYH2_k127_3363529_6 PFAM S-layer homology domain - - - 0.000297 51.0
PYH2_k127_3507332_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K03737 GO:0003674,GO:0003824,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0016491,GO:0050896,GO:0055114 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 442.0
PYH2_k127_3507332_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006762 417.0
PYH2_k127_3507332_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 389.0
PYH2_k127_3507332_3 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000593 230.0
PYH2_k127_3507332_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000004265 193.0
PYH2_k127_3507332_5 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000146 177.0
PYH2_k127_3507332_6 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000001403 136.0
PYH2_k127_3507332_7 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000555 124.0
PYH2_k127_3507332_8 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.0000000000000000000000006351 112.0
PYH2_k127_3507332_9 - - - - 0.000000005486 64.0
PYH2_k127_3525938_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 2.544e-246 779.0
PYH2_k127_3525938_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 416.0
PYH2_k127_3525938_2 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.000000000001177 74.0
PYH2_k127_3525938_3 NHL repeat - - - 0.0000524 55.0
PYH2_k127_3571257_0 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 400.0
PYH2_k127_3571257_1 Belongs to the MEMO1 family K06990 - - 0.000000000000000000000000000003889 130.0
PYH2_k127_3571257_2 PFAM Uncharacterised BCR, COG1649 K11931 - - 0.00004346 49.0
PYH2_k127_3695582_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 345.0
PYH2_k127_3695582_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 338.0
PYH2_k127_3695582_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006191 325.0
PYH2_k127_3695582_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005341 290.0
PYH2_k127_3695582_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003367 271.0
PYH2_k127_3695582_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000132 219.0
PYH2_k127_3695582_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000003595 213.0
PYH2_k127_3695582_7 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003372 190.0
PYH2_k127_3695582_8 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000164 167.0
PYH2_k127_3695582_9 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000003563 132.0
PYH2_k127_3800673_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003599 495.0
PYH2_k127_3800673_1 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 482.0
PYH2_k127_3800673_2 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003309 274.0
PYH2_k127_3800673_3 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000001044 108.0
PYH2_k127_3857792_0 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 323.0
PYH2_k127_3857792_1 metal-dependent phosphohydrolase HD region - - - 0.00000000000000000000000000000000000000000000000000003962 203.0
PYH2_k127_3857792_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.0000000000000000000000000004542 120.0
PYH2_k127_3857792_3 sigma factor antagonist activity K04757 - 2.7.11.1 0.0000000000000001353 94.0
PYH2_k127_3857792_4 Anaphase-promoting complex subunit 3 K03350 GO:0000070,GO:0000151,GO:0000152,GO:0000278,GO:0000280,GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005680,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016567,GO:0019538,GO:0019941,GO:0022402,GO:0030071,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0036211,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0048285,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051276,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065007,GO:0070013,GO:0070647,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0090068,GO:0097159,GO:0098813,GO:0140014,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905818,GO:1905820,GO:1990234,GO:2001252 - 0.000004109 53.0
PYH2_k127_3857792_5 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000009288 53.0
PYH2_k127_3916586_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.233e-228 714.0
PYH2_k127_3916586_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 2.193e-222 701.0
PYH2_k127_3916586_10 Putative RNA methylase family UPF0020 K15460 - 2.1.1.223 0.000000000000000000000000000000000000000001387 166.0
PYH2_k127_3916586_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000002583 115.0
PYH2_k127_3916586_12 Kelch motif - - - 0.000000000000000000000001338 112.0
PYH2_k127_3916586_13 - - - - 0.000000000000000001291 89.0
PYH2_k127_3916586_14 RDD family - - - 0.000000000000004636 86.0
PYH2_k127_3916586_15 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000002281 79.0
PYH2_k127_3916586_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000003313 75.0
PYH2_k127_3916586_17 Protein of unknown function (DUF3343) - - - 0.000000002 64.0
PYH2_k127_3916586_18 - - - - 0.00000007408 57.0
PYH2_k127_3916586_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 443.0
PYH2_k127_3916586_3 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 420.0
PYH2_k127_3916586_4 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 349.0
PYH2_k127_3916586_5 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409,K03070 GO:0000287,GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006508,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0019538,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0070011,GO:0070525,GO:0071704,GO:0090304,GO:0140030,GO:0140032,GO:0140096,GO:1901360,GO:1901564 2.3.1.234 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 351.0
PYH2_k127_3916586_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000007719 243.0
PYH2_k127_3916586_7 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001335 231.0
PYH2_k127_3916586_8 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000007621 207.0
PYH2_k127_3916586_9 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000001175 176.0
PYH2_k127_3918700_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003054 281.0
PYH2_k127_3918700_1 - - - - 0.00000000000000000000000000000000000000000000000000000000006455 220.0
PYH2_k127_3918700_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000007276 125.0
PYH2_k127_3918700_3 Pfam:N_methyl_2 K02650 - - 0.0000000000000000000001391 105.0
PYH2_k127_3918700_4 oligosaccharyl transferase activity - - - 0.0000000000000000000006868 107.0
PYH2_k127_3918700_5 PFAM O-Antigen ligase - - - 0.00000000000003282 87.0
PYH2_k127_3918700_6 transferase activity, transferring glycosyl groups K16148 - 2.4.1.342 0.000000000131 70.0
PYH2_k127_3923753_0 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003785 523.0
PYH2_k127_3923753_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 442.0
PYH2_k127_3923753_2 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008918 390.0
PYH2_k127_3923753_3 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 394.0
PYH2_k127_3923753_4 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000155 285.0
PYH2_k127_3923753_5 anaerobic respiration - - - 0.000000000000000000000000000000000000000000000000001043 205.0
PYH2_k127_3923753_6 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000002008 168.0
PYH2_k127_3923753_7 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000001201 125.0
PYH2_k127_3923753_8 Tetratricopeptide repeat - - - 0.0002096 46.0
PYH2_k127_3934541_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1884.0
PYH2_k127_3934541_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 4.71e-255 800.0
PYH2_k127_3934541_2 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000001318 228.0
PYH2_k127_3934541_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000008595 216.0
PYH2_k127_3934541_4 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.000007308 50.0
PYH2_k127_3940480_0 TIGRFAM molybdenum cofactor synthesis K03750,K07219 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 564.0
PYH2_k127_3940480_1 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006284 366.0
PYH2_k127_3940480_2 Putative pyruvate format-lyase activating enzyme (DUF1786) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005487 259.0
PYH2_k127_3940480_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.0000000000000000000000000000000000000000000000000000000000000002268 233.0
PYH2_k127_3940480_4 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000002095 230.0
PYH2_k127_3940480_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000003541 84.0
PYH2_k127_3940480_6 radical SAM domain protein K22227 - - 0.000156 51.0
PYH2_k127_4003399_0 radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 448.0
PYH2_k127_4003399_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 312.0
PYH2_k127_4003399_10 Fibronectin type III domain protein K21571 - - 0.00005061 52.0
PYH2_k127_4003399_11 - - - - 0.0002762 52.0
PYH2_k127_4003399_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 330.0
PYH2_k127_4003399_3 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002971 291.0
PYH2_k127_4003399_4 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005824 272.0
PYH2_k127_4003399_5 Domain of unknown function (DUF4872) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003241 253.0
PYH2_k127_4003399_6 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000000000000000003776 218.0
PYH2_k127_4003399_7 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000004251 211.0
PYH2_k127_4003399_8 acyl carrier protein K02078 - - 0.0000000000000001076 84.0
PYH2_k127_4003399_9 - - - - 0.0000000005085 66.0
PYH2_k127_4051765_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 527.0
PYH2_k127_4051765_1 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 372.0
PYH2_k127_4051765_2 Bacterial extracellular solute-binding protein K11069 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007849 365.0
PYH2_k127_4051765_3 ABC-type spermidine putrescine transport system, permease component I K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 353.0
PYH2_k127_4051765_4 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006433 310.0
PYH2_k127_4051765_5 anaerobic respiration - - - 0.00000000000000000000000000000000000000000000000000000000000000263 237.0
PYH2_k127_4087064_0 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009002 411.0
PYH2_k127_4087064_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 394.0
PYH2_k127_4087064_2 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 297.0
PYH2_k127_4087064_3 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000001493 154.0
PYH2_k127_4087064_4 Fibronectin type 3 domain - - - 0.000000000000000000000002534 117.0
PYH2_k127_4121320_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 456.0
PYH2_k127_4121320_1 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 342.0
PYH2_k127_4121320_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 315.0
PYH2_k127_4121320_3 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 293.0
PYH2_k127_4121320_4 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001354 287.0
PYH2_k127_421937_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 538.0
PYH2_k127_421937_1 stage 0 sporulation protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001925 273.0
PYH2_k127_421937_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000003172 136.0
PYH2_k127_421937_3 Kelch motif - - - 0.000000000000000000000000002657 131.0
PYH2_k127_421937_4 dextransucrase activity K01728,K06324,K08100,K18197,K20276 GO:0005575,GO:0005576 1.16.3.3,1.3.3.5,4.2.2.2,4.2.2.23 0.0000000001422 76.0
PYH2_k127_421937_5 PKD domain K09607,K19668 - 3.2.1.91 0.0000003137 65.0
PYH2_k127_421937_6 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000003361 53.0
PYH2_k127_4255758_0 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 401.0
PYH2_k127_4255758_1 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006397 394.0
PYH2_k127_4255758_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 334.0
PYH2_k127_4255758_3 PFAM TOBE domain - - - 0.000000000005559 68.0
PYH2_k127_4259794_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000004244 226.0
PYH2_k127_4259794_1 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000143 58.0
PYH2_k127_4259794_2 - - - - 0.00001637 55.0
PYH2_k127_4266429_0 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000644 478.0
PYH2_k127_4266429_1 alcohol dehydrogenase K00001,K00121 - 1.1.1.1,1.1.1.284 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008841 417.0
PYH2_k127_4266429_10 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000001379 197.0
PYH2_k127_4266429_11 SIS domain K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000003607 193.0
PYH2_k127_4266429_12 phosphoglycolate phosphatase activity - - - 0.000000000000000000000000000000000001746 157.0
PYH2_k127_4266429_13 Glycosyl transferase family 2 - - - 0.000000000000000000000000000000005622 137.0
PYH2_k127_4266429_2 ADP-L-glycero-beta-D-manno-heptose biosynthetic process K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 428.0
PYH2_k127_4266429_3 PFAM LOR SDH bifunctional enzyme conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 404.0
PYH2_k127_4266429_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710,K01784,K12450 - 4.2.1.46,4.2.1.76,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006568 389.0
PYH2_k127_4266429_5 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 377.0
PYH2_k127_4266429_6 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008482 367.0
PYH2_k127_4266429_7 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003711 336.0
PYH2_k127_4266429_8 Aminoglycoside phosphotransferase - - - 0.000000000000000000000000000000000000000000000000000000000001529 223.0
PYH2_k127_4266429_9 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000007732 207.0
PYH2_k127_4279521_0 metalloenzyme domain protein K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009991 458.0
PYH2_k127_4279521_1 SMART ABC-type transporter, periplasmic subunit family 3, ionotropic glutamate receptor K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 411.0
PYH2_k127_4279521_10 Phosphate ABC transporter substrate-binding protein K02040 - - 0.0000000000000000000000000000007691 133.0
PYH2_k127_4279521_11 response regulator receiver K02481 - - 0.000000000000000000004336 97.0
PYH2_k127_4279521_12 COG COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms Transcription - - - 0.000000000000000000006699 97.0
PYH2_k127_4279521_13 - - - - 0.000000000000000008443 84.0
PYH2_k127_4279521_14 - - - - 0.000000000000002482 79.0
PYH2_k127_4279521_15 Thioredoxin-like - - - 0.0000000000001893 78.0
PYH2_k127_4279521_16 denitrification pathway - - - 0.000003687 59.0
PYH2_k127_4279521_2 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 400.0
PYH2_k127_4279521_3 ATPases associated with a variety of cellular activities K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 355.0
PYH2_k127_4279521_4 General secretory system II, protein E domain protein K02454 - - 0.000000000000000000000000000000000000000000000000000000000000001461 223.0
PYH2_k127_4279521_5 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000001768 211.0
PYH2_k127_4279521_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000002149 216.0
PYH2_k127_4279521_7 Histidine kinase K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000007097 204.0
PYH2_k127_4279521_8 DIM6 NTAB family - - - 0.000000000000000000000000000000000000000000002747 170.0
PYH2_k127_4279521_9 EamA-like transporter family - - - 0.0000000000000000000000000000003602 136.0
PYH2_k127_4299812_0 BadF BadG BcrA BcrD - - - 0.0 1176.0
PYH2_k127_4299812_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002311 444.0
PYH2_k127_4299812_2 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006835 362.0
PYH2_k127_4299812_3 Putative glutamine amidotransferase K07114 - - 0.0000000000000000000000000000000000000000000000000000000000000000000087 264.0
PYH2_k127_4299812_4 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000001527 158.0
PYH2_k127_4299812_5 Aerotolerance regulator N-terminal - - - 0.000007891 59.0
PYH2_k127_4322151_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1040.0
PYH2_k127_4322151_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.824e-305 957.0
PYH2_k127_4322151_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 316.0
PYH2_k127_4322151_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000001577 124.0
PYH2_k127_4322151_4 DNA polymerase III beta subunit K02338 - 2.7.7.7 0.0000000000000000756 82.0
PYH2_k127_435582_0 PFAM major facilitator superfamily MFS_1 K03446 - - 8.046e-231 725.0
PYH2_k127_435582_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000486 276.0
PYH2_k127_435582_2 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002204 266.0
PYH2_k127_435582_3 PFAM secretion protein HlyD K03543 - - 0.0000000000000000000000000000000000000000000000000000000001274 207.0
PYH2_k127_4364907_0 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 383.0
PYH2_k127_4364907_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.0000000000000000000000000000000000000000000000000000000000007298 223.0
PYH2_k127_4364907_2 Tetraacyldisaccharide-1-P 4'-kinase K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000006767 184.0
PYH2_k127_4364907_3 Domain of unknown function (DUF4175) - - - 0.000000000000000000000000000000000000000001086 181.0
PYH2_k127_4364907_4 Phospholipid methyltransferase - - - 0.00000000000000000000000000000004364 133.0
PYH2_k127_4364907_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000003838 78.0
PYH2_k127_4364907_6 PFAM ATP synthase subunit C K02124 - - 0.00000000000004112 78.0
PYH2_k127_4364907_7 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000001617 61.0
PYH2_k127_4364907_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000002898 66.0
PYH2_k127_444237_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 4.82e-200 639.0
PYH2_k127_444237_1 Bacterial regulatory protein, Fis family - - - 0.000000000000000009088 94.0
PYH2_k127_444237_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0001527 46.0
PYH2_k127_4465077_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 565.0
PYH2_k127_4465077_1 Abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 359.0
PYH2_k127_4465077_2 Efflux ABC transporter permease protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 358.0
PYH2_k127_4465077_3 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007267 354.0
PYH2_k127_4465077_4 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006571 262.0
PYH2_k127_4465077_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000004134 196.0
PYH2_k127_4465077_6 SNARE associated Golgi protein K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000001373 186.0
PYH2_k127_4465077_7 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000007396 146.0
PYH2_k127_4465077_8 Domain of unknown function (DUF4388) K03413 - - 0.0000000000000000000000000000001579 132.0
PYH2_k127_4465077_9 Protein of unknown function (DUF2905) - - - 0.0000005201 52.0
PYH2_k127_4483857_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.491e-217 689.0
PYH2_k127_4483857_1 ACT domain K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 499.0
PYH2_k127_4483857_2 Phenazine biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 368.0
PYH2_k127_4483857_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001966 279.0
PYH2_k127_4483857_4 SLBB domain K02237 - - 0.00000000000164 74.0
PYH2_k127_4483857_5 isomerase activity K01821 - 5.3.2.6 0.0000000003953 66.0
PYH2_k127_4514754_0 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000007527 137.0
PYH2_k127_4514754_1 secretion system protein K02669 - - 0.000000000000000000000000000000002284 133.0
PYH2_k127_4514754_2 COG0457 FOG TPR repeat - - - 0.0000000000003856 76.0
PYH2_k127_4514754_3 Glutathione peroxidase - - - 0.00000843 57.0
PYH2_k127_4533677_0 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 461.0
PYH2_k127_4533677_1 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000003122 192.0
PYH2_k127_4533677_2 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000004116 188.0
PYH2_k127_4553603_0 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 302.0
PYH2_k127_4553603_1 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000003027 250.0
PYH2_k127_4553603_2 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000001933 100.0
PYH2_k127_4553603_3 Regulator of chromosome condensation (RCC1) repeat - - - 0.00000000002862 76.0
PYH2_k127_4553603_4 - - - - 0.000000001415 71.0
PYH2_k127_4574579_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008116 490.0
PYH2_k127_4574579_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 362.0
PYH2_k127_4574579_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 260.0
PYH2_k127_4574579_3 PFAM Rubrerythrin - - - 0.000000000000000000000004221 108.0
PYH2_k127_4574579_4 AAA domain K07133 - - 0.000000000000000683 81.0
PYH2_k127_4574579_5 ResB-like family - - - 0.0000000000002212 81.0
PYH2_k127_4795102_0 Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 543.0
PYH2_k127_4795102_1 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000001382 239.0
PYH2_k127_4795102_2 - - - - 0.0000000000000000000000000000000488 132.0
PYH2_k127_4795102_3 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000001155 73.0
PYH2_k127_4795102_4 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000003988 56.0
PYH2_k127_4795102_5 Transcriptional regulator - - - 0.000003435 55.0
PYH2_k127_4851327_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 385.0
PYH2_k127_4851327_1 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 372.0
PYH2_k127_4851327_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 302.0
PYH2_k127_4851327_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000009569 217.0
PYH2_k127_4851327_4 PFAM Radical SAM - - - 0.00000000000000000000000000000000000103 153.0
PYH2_k127_4857099_0 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 445.0
PYH2_k127_4857099_1 WD40-like Beta Propeller Repeat K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 417.0
PYH2_k127_4857099_2 116 kDa subunit K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 314.0
PYH2_k127_4857099_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000001021 177.0
PYH2_k127_4857099_4 Belongs to the V-ATPase proteolipid subunit family K02124 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000002091 143.0
PYH2_k127_4857099_5 metal-dependent phosphohydrolase HD region - - - 0.000000005477 67.0
PYH2_k127_4893355_0 Belongs to the peptidase M48B family K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 339.0
PYH2_k127_4893355_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001809 271.0
PYH2_k127_4893355_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000002403 241.0
PYH2_k127_4893355_3 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000199 164.0
PYH2_k127_4893355_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000004626 144.0
PYH2_k127_4893355_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.00001737 56.0
PYH2_k127_4893355_6 Putative zinc-finger - - - 0.0005947 49.0
PYH2_k127_4923825_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 8.978e-226 713.0
PYH2_k127_4923825_1 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006214 600.0
PYH2_k127_4923825_2 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 554.0
PYH2_k127_4923825_3 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 378.0
PYH2_k127_4923825_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 379.0
PYH2_k127_4923825_5 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006189 312.0
PYH2_k127_4923825_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 306.0
PYH2_k127_4923825_7 Two component signalling adaptor domain K03408 - - 0.00000000000000000000000000000000000004214 149.0
PYH2_k127_4923825_8 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000001947 88.0
PYH2_k127_4983576_0 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000653 274.0
PYH2_k127_4983576_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000002407 200.0
PYH2_k127_4983576_2 phosphorelay signal transduction system K07658 - - 0.00000000000000000000000000000006008 128.0
PYH2_k127_4983576_3 peptidyl-tyrosine sulfation - - - 0.0000000003651 68.0
PYH2_k127_4997109_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005907 479.0
PYH2_k127_4997109_1 4Fe-4S single cluster domain K01843 - 5.4.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 352.0
PYH2_k127_4997109_2 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001965 297.0
PYH2_k127_4997109_3 LemA family K03744 - - 0.0000000000000000000000000000000000000000000001428 173.0
PYH2_k127_4997109_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006093 134.0
PYH2_k127_4997109_5 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000008821 86.0
PYH2_k127_4997109_7 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000003495 77.0
PYH2_k127_4997109_8 Belongs to the glycosyl hydrolase 43 family - - - 0.00008178 57.0
PYH2_k127_5025012_0 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000000000002625 210.0
PYH2_k127_5025012_2 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00000383 60.0
PYH2_k127_5034325_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 9.373e-195 633.0
PYH2_k127_5034325_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 462.0
PYH2_k127_5034325_2 Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000402 232.0
PYH2_k127_5034325_3 SMART AAA ATPase K02450 - - 0.00000000000000000000000000000000007994 141.0
PYH2_k127_5034325_4 Type II secretion system protein B K02451 - - 0.000000004858 67.0
PYH2_k127_5064965_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003316 283.0
PYH2_k127_5064965_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000008845 220.0
PYH2_k127_5071711_0 probably responsible for the translocation of the substrate across the membrane K02037,K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 363.0
PYH2_k127_5071711_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 347.0
PYH2_k127_5071711_2 Binding-protein-dependent transport system inner membrane component K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 350.0
PYH2_k127_5071711_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 311.0
PYH2_k127_5071711_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001703 280.0
PYH2_k127_5097731_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006273 289.0
PYH2_k127_5097731_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000007264 184.0
PYH2_k127_5097731_2 Single-stranded DNA-binding protein K03111 - - 0.00000000000000000000000000000000000005979 147.0
PYH2_k127_5097731_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000395 147.0
PYH2_k127_5097731_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000000004086 107.0
PYH2_k127_5097731_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000002135 81.0
PYH2_k127_5097731_6 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.00000000001041 77.0
PYH2_k127_5115986_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 450.0
PYH2_k127_5115986_1 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 376.0
PYH2_k127_5115986_2 uracil phosphoribosyltransferase activity K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044464,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.0000000000000000000000000000000000000004239 151.0
PYH2_k127_5115986_3 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000000000002267 152.0
PYH2_k127_5115986_4 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000004744 136.0
PYH2_k127_5115986_5 Oxidoreductase NAD-binding domain K02823 - - 0.00000001633 57.0
PYH2_k127_5129735_0 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000007283 237.0
PYH2_k127_5129735_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000002822 232.0
PYH2_k127_5129735_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000003216 191.0
PYH2_k127_5129735_3 Domain of unknown function (DUF2088) - - - 0.000000000000000000000000000000000000000000004623 175.0
PYH2_k127_5129735_4 ComF family K02242 - - 0.00000000000000000000000000000000004286 144.0
PYH2_k127_5129735_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000001691 108.0
PYH2_k127_5190625_0 Phosphate acyltransferases K01897 - 6.2.1.3 9.72e-228 723.0
PYH2_k127_5190625_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000004528 255.0
PYH2_k127_5190625_2 alcohol dehydrogenase K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000009019 247.0
PYH2_k127_5225198_0 Peptidylprolyl isomerase K01802,K03769,K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 323.0
PYH2_k127_5225198_1 SMART helicase c2 K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 309.0
PYH2_k127_5225198_2 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000002027 264.0
PYH2_k127_5225198_3 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000004175 175.0
PYH2_k127_5225198_4 TIGRFAM regulatory protein, FmdB - - - 0.0000000000004221 74.0
PYH2_k127_5255342_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002657 285.0
PYH2_k127_5255342_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001024 263.0
PYH2_k127_5255342_2 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K00772,K03783 - 2.4.2.1,2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000002817 242.0
PYH2_k127_5255342_3 Ppx GppA K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000001378 148.0
PYH2_k127_5255342_4 cheY-homologous receiver domain - - - 0.000000000000000000002244 103.0
PYH2_k127_5255342_5 Domain of unknown function (DUF4115) - - - 0.00000000000000000001215 100.0
PYH2_k127_5255342_6 Tetratricopeptide TPR_2 repeat protein - - - 0.0005304 52.0
PYH2_k127_5263330_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 540.0
PYH2_k127_5263330_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005295 276.0
PYH2_k127_5263330_2 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000001319 210.0
PYH2_k127_5263330_3 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain - - - 0.00000000000000000000000000000000000000001889 174.0
PYH2_k127_5263330_4 Type II secretion system (T2SS), protein E, N-terminal domain K02652 - - 0.0000000000000000000000000000001024 134.0
PYH2_k127_5263330_5 PFAM histidine kinase, HAMP region domain protein - - - 0.000000000000000796 81.0
PYH2_k127_5344481_0 Chase2 domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005428 491.0
PYH2_k127_5344481_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000005554 213.0
PYH2_k127_5344481_2 PilT protein domain protein - - - 0.00000000000000008766 85.0
PYH2_k127_5344481_3 OmpA family - - - 0.00007093 47.0
PYH2_k127_543490_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 5.686e-298 939.0
PYH2_k127_543490_1 pfam abc1 K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 495.0
PYH2_k127_543490_2 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004413 436.0
PYH2_k127_543490_3 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K06898,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002698 290.0
PYH2_k127_543490_4 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001061 272.0
PYH2_k127_543490_5 - - - - 0.0003054 47.0
PYH2_k127_5443158_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 9.886e-206 653.0
PYH2_k127_5443158_1 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 489.0
PYH2_k127_5443158_2 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 357.0
PYH2_k127_5443158_3 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000005338 145.0
PYH2_k127_5510492_0 Flavin containing amine oxidoreductase K00231,K01854 - 1.3.3.15,1.3.3.4,5.4.99.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 423.0
PYH2_k127_5510492_1 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 362.0
PYH2_k127_5510492_2 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 355.0
PYH2_k127_5510492_3 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000447 286.0
PYH2_k127_5613126_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005315 265.0
PYH2_k127_5613126_2 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.000000000000000000000000000000000000000000000000000000000000005204 221.0
PYH2_k127_5619935_0 Cache domain - - - 1.493e-258 810.0
PYH2_k127_5619935_1 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 355.0
PYH2_k127_5619935_2 ABC transporter K09817 - - 0.000000000000000000000000000000000000000000000000000000000000000001164 237.0
PYH2_k127_5619935_3 PFAM periplasmic solute binding protein K09815 - - 0.00000000000000000000000000000000000000000000000000000000000005793 227.0
PYH2_k127_5619935_4 ABC-type Mn2 Zn2 transport system, permease component K09816,K09819,K19976 - - 0.0000000000000000000000000000000000000000000000000000000000001176 222.0
PYH2_k127_5619935_5 Domain of unknown function (DUF296) K06934 - - 0.00000000000000000000000000001172 126.0
PYH2_k127_5619935_6 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000003663 81.0
PYH2_k127_5647264_0 ABC transporter K06020 - 3.6.3.25 1.203e-281 877.0
PYH2_k127_5647264_1 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 1.697e-254 801.0
PYH2_k127_5647264_10 Flavodoxin-like fold - - - 0.00000000000000000000000000001264 132.0
PYH2_k127_5647264_11 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000003009 99.0
PYH2_k127_5647264_12 - - - - 0.0000000000000000000008993 100.0
PYH2_k127_5647264_13 Rubrerythrin - - - 0.0000000000000008479 84.0
PYH2_k127_5647264_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000002905 70.0
PYH2_k127_5647264_15 Domain of unknown function (DUF4388) - - - 0.0000003407 59.0
PYH2_k127_5647264_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 428.0
PYH2_k127_5647264_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 335.0
PYH2_k127_5647264_4 ThiS-like ubiquitin K03148 - 2.7.7.73 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 299.0
PYH2_k127_5647264_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000003313 268.0
PYH2_k127_5647264_6 Inositol monophosphatase K01082,K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000009693 268.0
PYH2_k127_5647264_7 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000002647 207.0
PYH2_k127_5647264_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000001774 186.0
PYH2_k127_5647264_9 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000000000000001129 143.0
PYH2_k127_5685828_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009314,GO:0009380,GO:0009381,GO:0009628,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0 1268.0
PYH2_k127_5685828_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 8.405e-240 756.0
PYH2_k127_5685828_10 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000003397 130.0
PYH2_k127_5685828_11 - - - - 0.000000000000000000000000006795 124.0
PYH2_k127_5685828_12 Lysylphosphatidylglycerol synthase TM region - - - 0.00000000000000000003027 103.0
PYH2_k127_5685828_13 subunit c K02119 - - 0.0000000000000000004078 99.0
PYH2_k127_5685828_14 4Fe-4S binding domain - - - 0.000000000000000562 82.0
PYH2_k127_5685828_15 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000001005 79.0
PYH2_k127_5685828_16 - - - - 0.000000000002437 81.0
PYH2_k127_5685828_17 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000001773 64.0
PYH2_k127_5685828_18 general secretion pathway protein K02457,K02650 - - 0.0000002132 59.0
PYH2_k127_5685828_19 Putative regulatory protein - - - 0.000004084 56.0
PYH2_k127_5685828_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.064e-214 676.0
PYH2_k127_5685828_20 Tetratricopeptide TPR_2 repeat protein - - - 0.000005899 59.0
PYH2_k127_5685828_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATP-binding protein, C-terminal domain K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 376.0
PYH2_k127_5685828_4 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001807 372.0
PYH2_k127_5685828_5 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
PYH2_k127_5685828_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000001528 213.0
PYH2_k127_5685828_7 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000004432 198.0
PYH2_k127_5685828_8 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000002568 180.0
PYH2_k127_5685828_9 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000164 159.0
PYH2_k127_5757369_0 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 340.0
PYH2_k127_5757369_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000002452 195.0
PYH2_k127_5757369_2 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000005269 80.0
PYH2_k127_5757369_3 Proto-chlorophyllide reductase 57 kD subunit - - - 0.0000000489 56.0
PYH2_k127_577186_0 P-type ATPase K17686 - 3.6.3.54 1.384e-235 758.0
PYH2_k127_577186_1 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009249 525.0
PYH2_k127_577186_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 469.0
PYH2_k127_577186_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586,K05366 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008836,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016829,GO:0016830,GO:0016831,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046451,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.1.129,3.4.16.4,4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 316.0
PYH2_k127_577186_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 316.0
PYH2_k127_577186_5 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000001077 207.0
PYH2_k127_577186_6 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000001101 208.0
PYH2_k127_577186_7 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000000000000133 172.0
PYH2_k127_577186_8 - - - - 0.0000005911 59.0
PYH2_k127_5791301_0 ABC transporter K06158 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 613.0
PYH2_k127_5791301_1 Natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 427.0
PYH2_k127_5791301_2 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000869 262.0
PYH2_k127_5824869_0 PFAM AICARFT IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 2.471e-208 657.0
PYH2_k127_5824869_1 PFAM Curli production assembly transport component CsgG - - - 0.000000000000000000000000000000000000000000000001203 183.0
PYH2_k127_5869090_0 Sulfate ABC transporter, periplasmic sulfate-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002162 508.0
PYH2_k127_5869090_1 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 429.0
PYH2_k127_5869090_2 sulfate ABC transporter K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 421.0
PYH2_k127_5869090_3 Sulfate ABC transporter, permease protein CysT K02046 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 398.0
PYH2_k127_5869090_4 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000323 328.0
PYH2_k127_5869090_5 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005948 266.0
PYH2_k127_5869090_6 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000008672 190.0
PYH2_k127_5869090_7 dienelactone hydrolase - - - 0.0000000000000000000000000000000001689 137.0
PYH2_k127_5869090_8 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000004991 130.0
PYH2_k127_5936265_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 380.0
PYH2_k127_5936265_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001075 291.0
PYH2_k127_5936265_10 PFAM response regulator receiver - - - 0.00000000000000000000002872 103.0
PYH2_k127_5936265_11 lysyltransferase activity K07027 - - 0.0000000000000000001461 104.0
PYH2_k127_5936265_12 Periplasmic component of the Tol biopolymer transport system - - - 0.000000000000000001375 97.0
PYH2_k127_5936265_13 Prokaryotic N-terminal methylation motif K02456,K02457,K02458,K02459,K02655,K10926 - - 0.00000000000000006287 94.0
PYH2_k127_5936265_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.00000000000000000000000000000000000000000000000000004964 192.0
PYH2_k127_5936265_3 Coenzyme F420 hydrogenase/dehydrogenase, beta subunit N-term K00441 - 1.12.98.1 0.00000000000000000000000000000000000000000000000008763 192.0
PYH2_k127_5936265_4 O-methyltransferase, family 2 - - - 0.0000000000000000000000000000000000000000000000001287 192.0
PYH2_k127_5936265_5 PFAM Metal-dependent phosphohydrolase, HD K06951 - - 0.000000000000000000000000000000000000000000000002126 180.0
PYH2_k127_5936265_6 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000001086 175.0
PYH2_k127_5936265_7 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000007277 180.0
PYH2_k127_5936265_8 PFAM nuclease (SNase domain protein) - - - 0.000000000000000000000000000000000000001138 154.0
PYH2_k127_5936265_9 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000005997 129.0
PYH2_k127_6025532_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004393 276.0
PYH2_k127_6025532_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000001915 200.0
PYH2_k127_6025532_2 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000001229 193.0
PYH2_k127_6025532_3 ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000000000000000000008787 190.0
PYH2_k127_6025532_4 EamA-like transporter family - - - 0.0000000000000000000000000000000000004961 152.0
PYH2_k127_6025532_5 Chemotaxis protein CheY K02658 - - 0.00000000000000000000000002657 115.0
PYH2_k127_6025532_6 PFAM ATP-binding region ATPase domain protein K07768 GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009405,GO:0009987,GO:0016020,GO:0016310,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044419,GO:0044464,GO:0046777,GO:0051704,GO:0071704,GO:0071944,GO:1901564 2.7.13.3 0.00000000000000000005499 105.0
PYH2_k127_6025532_7 SpoVG K06412 - - 0.0000000000000001148 83.0
PYH2_k127_6025532_8 response regulator receiver K03413 - - 0.00000000007444 70.0
PYH2_k127_6025532_9 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000007836 68.0
PYH2_k127_6050663_0 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007177 303.0
PYH2_k127_6050663_1 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 301.0
PYH2_k127_6050663_2 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003231 267.0
PYH2_k127_6050663_3 AAA domain K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000004857 239.0
PYH2_k127_6050663_4 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000006721 177.0
PYH2_k127_6050663_5 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000003489 166.0
PYH2_k127_6086405_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001075 286.0
PYH2_k127_6086405_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001309 260.0
PYH2_k127_6086405_2 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000003911 152.0
PYH2_k127_6086405_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000000000000000001373 135.0
PYH2_k127_6086405_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000004785 111.0
PYH2_k127_6086405_5 - - - - 0.00000000000004076 86.0
PYH2_k127_6104976_0 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 260.0
PYH2_k127_6104976_1 MacB-like periplasmic core domain - - - 0.0000000000000000000000000000000000000008462 153.0
PYH2_k127_6104976_2 nuclease activity K18828 - - 0.00000000000000000000000000000000000003386 147.0
PYH2_k127_6104976_3 Papain family cysteine protease - - - 0.00000000000000000000000005274 114.0
PYH2_k127_6104976_4 Pectinesterase K01051 - 3.1.1.11 0.0000000000000009201 93.0
PYH2_k127_6104976_5 - - - - 0.00000002883 59.0
PYH2_k127_613627_0 Heat shock 70 kDa protein K04043 - - 4.207e-297 922.0
PYH2_k127_613627_1 Cytochrome c554 and c-prime - - - 2.575e-221 714.0
PYH2_k127_613627_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000005298 141.0
PYH2_k127_613627_3 smart pdz dhr glgf K04771 - 3.4.21.107 0.00000000005244 69.0
PYH2_k127_613627_4 - - - - 0.000000008624 66.0
PYH2_k127_613627_5 Predicted periplasmic protein (DUF2092) - - - 0.00000002971 55.0
PYH2_k127_6201253_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.47e-253 795.0
PYH2_k127_6201253_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.001e-196 628.0
PYH2_k127_6201253_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 554.0
PYH2_k127_6201253_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000334 494.0
PYH2_k127_6201253_4 TIGRFAM acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000004794 224.0
PYH2_k127_6201253_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000292 199.0
PYH2_k127_6201253_6 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000005516 171.0
PYH2_k127_6201253_7 PFAM Peptidase M22, glycoprotease K14742 - - 0.000000000000000000000000000000001495 139.0
PYH2_k127_6201253_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000005722 106.0
PYH2_k127_6201253_9 - K09794 - - 0.0000002853 55.0
PYH2_k127_6202107_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003516 334.0
PYH2_k127_6202107_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001036 318.0
PYH2_k127_6202107_2 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009638 273.0
PYH2_k127_6202107_3 Deoxynucleoside kinase K15518 - 2.7.1.113 0.000000000000000000000000000000000000000000000000000000000000001789 222.0
PYH2_k127_6202107_4 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000008043 160.0
PYH2_k127_6202107_5 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000002661 139.0
PYH2_k127_6231838_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000712 391.0
PYH2_k127_6231838_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000005754 121.0
PYH2_k127_6239637_0 PFAM peptidase M29, aminopeptidase II K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 382.0
PYH2_k127_6239637_1 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 352.0
PYH2_k127_6239637_10 Protein of unknown function (DUF3179) - - - 0.000000000006502 73.0
PYH2_k127_6239637_11 Tetratricopeptide repeat - - - 0.0000000007689 67.0
PYH2_k127_6239637_12 FecR protein - - - 0.0000000779 62.0
PYH2_k127_6239637_2 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004586 321.0
PYH2_k127_6239637_3 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 292.0
PYH2_k127_6239637_4 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000005763 201.0
PYH2_k127_6239637_5 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000003438 171.0
PYH2_k127_6239637_6 COG1597 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000002399 126.0
PYH2_k127_6239637_7 preribosome binding K07574 GO:0000027,GO:0000028,GO:0000966,GO:0000967,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0034470,GO:0034471,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042273,GO:0042274,GO:0043021,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1990275 - 0.00000000000000000000000001371 116.0
PYH2_k127_6239637_8 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000008487 108.0
PYH2_k127_6239637_9 AsnC family - - - 0.0000000000000000118 84.0
PYH2_k127_6272549_0 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 539.0
PYH2_k127_6272549_1 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003408 347.0
PYH2_k127_6272549_2 Hemerythrin HHE cation binding domain protein - - - 0.000000000000000000000000000000002701 131.0
PYH2_k127_6272549_3 metallopeptidase activity - - - 0.000002983 57.0
PYH2_k127_6382629_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 376.0
PYH2_k127_6382629_1 response regulator, receiver K13069,K18967 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.000000000000000000000004471 112.0
PYH2_k127_6412299_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000006902 143.0
PYH2_k127_6412299_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000005674 142.0
PYH2_k127_6412299_3 PFAM UvrB UvrC protein K08999,K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000009403 129.0
PYH2_k127_6412299_4 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000003238 83.0
PYH2_k127_6558236_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 466.0
PYH2_k127_6558236_1 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 308.0
PYH2_k127_6558236_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000008778 249.0
PYH2_k127_660571_0 Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH K00033 - 1.1.1.343,1.1.1.44 2.605e-203 644.0
PYH2_k127_660571_1 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009671 278.0
PYH2_k127_660571_2 beta-propeller repeat - - - 0.000000000000000000000000000000000003627 152.0
PYH2_k127_660571_3 - - - - 0.0000000000000000000000000000000005153 138.0
PYH2_k127_660571_4 - - - - 0.0006962 51.0
PYH2_k127_6629135_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005898 396.0
PYH2_k127_6629135_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 381.0
PYH2_k127_6629135_10 oligosaccharyl transferase activity - - - 0.00000000000000000000005669 115.0
PYH2_k127_6629135_11 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000001361 113.0
PYH2_k127_6629135_12 PFAM glutaredoxin - - - 0.0000000000000000000006205 98.0
PYH2_k127_6629135_13 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000007379 89.0
PYH2_k127_6629135_14 - - - - 0.00005475 52.0
PYH2_k127_6629135_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.00000000000000000000000000000000000000000000000000000000000000003397 229.0
PYH2_k127_6629135_3 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000006643 223.0
PYH2_k127_6629135_4 Metal-dependent phosphohydrolase, HD region - - - 0.000000000000000000000000000000000000000000000000000665 198.0
PYH2_k127_6629135_5 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000000000000000005536 200.0
PYH2_k127_6629135_6 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000005913 181.0
PYH2_k127_6629135_7 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000004253 166.0
PYH2_k127_6629135_8 - - - - 0.0000000000000000000000000000000000001557 159.0
PYH2_k127_6629135_9 Abnormal spindle-like microcephaly-assoc'd, ASPM-SPD-2-Hydin - - - 0.0000000000000000000000000003456 130.0
PYH2_k127_6696045_0 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 368.0
PYH2_k127_6696045_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009024 303.0
PYH2_k127_6696045_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000001529 211.0
PYH2_k127_6696045_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000004165 138.0
PYH2_k127_6696045_4 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.000000000006933 79.0
PYH2_k127_6696045_5 C-terminal four TMM region of protein-O-mannosyltransferase K00728 - 2.4.1.109 0.0000000000203 77.0
PYH2_k127_6728704_0 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000474 239.0
PYH2_k127_6728704_1 Polysaccharide biosynthesis protein - - - 0.000000000000000000000000000000000000000000006057 183.0
PYH2_k127_6728704_2 histidine kinase HAMP region domain protein - - - 0.000000004025 60.0
PYH2_k127_6749836_0 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 1.558e-253 798.0
PYH2_k127_6749836_1 SMART Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 431.0
PYH2_k127_6749836_2 TIGRFAM TRAP transporter solute receptor, TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 379.0
PYH2_k127_6749836_3 Domain of unknown function (DUF1850) - - - 0.00000000000000000000000000000000000000000000000000000002811 201.0
PYH2_k127_6821742_0 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006052 247.0
PYH2_k127_6821742_1 Parallel beta-helix repeats - - - 0.000000000000000000000000000000000000000000000000007931 199.0
PYH2_k127_6821742_2 Peptidase family M50 - - - 0.00000000000000000000003133 102.0
PYH2_k127_6858522_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006591 531.0
PYH2_k127_6858522_1 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002444 425.0
PYH2_k127_6858522_2 Domain of unknown function (DUF4143) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 400.0
PYH2_k127_6858522_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 304.0
PYH2_k127_6858522_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
PYH2_k127_6858522_5 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.0000000000000000000000000000000000000000000000000000002828 198.0
PYH2_k127_6858522_6 - - - - 0.0006046 45.0
PYH2_k127_6867249_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 7.185e-206 672.0
PYH2_k127_6867249_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 361.0
PYH2_k127_6867249_2 glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000005525 183.0
PYH2_k127_6904485_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 583.0
PYH2_k127_6904485_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD K03581 - 3.1.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 522.0
PYH2_k127_6904485_2 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009417 299.0
PYH2_k127_6904485_3 arylsulfatase activity K07014 - - 0.000000000000000000000000000000000000000000000000000000134 218.0
PYH2_k127_6904485_4 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000009821 183.0
PYH2_k127_6904485_5 - - - - 0.00000000000000000000001137 110.0
PYH2_k127_6904485_6 lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000003544 113.0
PYH2_k127_7010273_0 PFAM ABC transporter related K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 363.0
PYH2_k127_7010273_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003482 372.0
PYH2_k127_7010273_10 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000006629 124.0
PYH2_k127_7010273_11 Outer membrane lipoprotein - - - 0.0000000000000000000003416 106.0
PYH2_k127_7010273_12 Lysin motif - - - 0.000000000000000000001433 108.0
PYH2_k127_7010273_13 Protein of unknown function (DUF721) - - - 0.00000000005406 69.0
PYH2_k127_7010273_14 RDD family - - - 0.000003043 49.0
PYH2_k127_7010273_2 PFAM Extracellular solute-binding protein, family 3 K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003581 342.0
PYH2_k127_7010273_3 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000774 327.0
PYH2_k127_7010273_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007863 310.0
PYH2_k127_7010273_5 Transcriptional regulator IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 293.0
PYH2_k127_7010273_6 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.0000000000000000000000000000000000000000000000000000000003408 221.0
PYH2_k127_7010273_7 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K02029,K10002 - - 0.00000000000000000000000000000000000000000000000000001584 201.0
PYH2_k127_7010273_8 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000002564 167.0
PYH2_k127_7010273_9 histidine kinase A domain protein - - - 0.00000000000000000000000000000003447 135.0
PYH2_k127_7158766_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 535.0
PYH2_k127_7158766_1 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000274 306.0
PYH2_k127_7158766_2 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 298.0
PYH2_k127_7158766_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000002914 213.0
PYH2_k127_7158766_4 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000003599 176.0
PYH2_k127_7158766_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000000000001681 115.0
PYH2_k127_7158766_6 electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000001503 94.0
PYH2_k127_72195_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 586.0
PYH2_k127_72195_1 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 0.000000000000000000000000000000000000000000000000000000000000003802 232.0
PYH2_k127_72195_2 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000000000000000000008467 211.0
PYH2_k127_72195_3 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000001724 144.0
PYH2_k127_72195_4 PFAM CheW domain protein K03408 - - 0.00000005072 57.0
PYH2_k127_7244859_0 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005097 338.0
PYH2_k127_7244859_1 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000000000000001119 201.0
PYH2_k127_7244859_2 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000004221 190.0
PYH2_k127_7244859_3 - - - - 0.000000000000000000000000000000000422 149.0
PYH2_k127_7362343_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 554.0
PYH2_k127_7362343_1 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 447.0
PYH2_k127_7362343_2 Rhomboid family - - - 0.00000000000000000000000000000000000000005666 166.0
PYH2_k127_7367144_0 Domain of unknown function (DUF1972) K12996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 412.0
PYH2_k127_7367144_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001064 269.0
PYH2_k127_7367144_2 Male sterility protein - - - 0.00000000000000000000000000000000000000001104 156.0
PYH2_k127_7367144_3 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0004167 53.0
PYH2_k127_7381229_0 protein methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 528.0
PYH2_k127_7381229_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 520.0
PYH2_k127_7381229_2 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 308.0
PYH2_k127_7381229_3 TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000611 224.0
PYH2_k127_7381229_4 Peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.000000000000000000000000000000000000002697 153.0
PYH2_k127_7381229_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000002679 119.0
PYH2_k127_7381229_6 response regulator K02485,K03413 - - 0.00000000000000006364 84.0
PYH2_k127_7381229_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000001283 72.0
PYH2_k127_7381229_8 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000008497 70.0
PYH2_k127_7384999_0 Putative glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 331.0
PYH2_k127_7384999_1 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000003135 232.0
PYH2_k127_7384999_2 Domain of unknown function (DUF4833) - - - 0.000000000000000000000005958 109.0
PYH2_k127_7384999_3 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000006455 108.0
PYH2_k127_7384999_4 Histidine kinase - - - 0.00000000000000002536 90.0
PYH2_k127_7394893_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 2.195e-286 897.0
PYH2_k127_7394893_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.0000000000000000000000000000000000000000000000004146 178.0
PYH2_k127_7394893_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067,K01790,K19997 - 1.1.1.133,5.1.3.13,5.1.3.26 0.000000000000000000000000000000001441 134.0
PYH2_k127_7394893_3 C-terminal four TMM region of protein-O-mannosyltransferase - - - 0.0000007886 62.0
PYH2_k127_7402505_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 4.01e-233 732.0
PYH2_k127_7402505_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K00895,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 419.0
PYH2_k127_7402505_2 response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000001431 231.0
PYH2_k127_7403762_0 Xaa-Pro dipeptidase - - - 0.000000000000000000000000000000000000000000000000000000002843 212.0
PYH2_k127_7403762_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000003129 180.0
PYH2_k127_7403762_2 Roadblock/LC7 domain - - - 0.0000001311 58.0
PYH2_k127_7403762_3 Tetratricopeptide repeat - - - 0.0000005074 56.0
PYH2_k127_7409909_0 SMART chemotaxis sensory transducer K03406 - - 0.000000000000000000000000000000000000000000000000000000004803 213.0
PYH2_k127_7409909_1 transcriptional regulator K07665 - - 0.00000000000002377 80.0
PYH2_k127_7409909_2 Bacterial regulatory protein, Fis family K02481,K07713 - - 0.00001983 49.0
PYH2_k127_7430677_0 glycosyl transferase, family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008543 519.0
PYH2_k127_7430677_1 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 502.0
PYH2_k127_7430677_10 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.0000000000007559 69.0
PYH2_k127_7430677_2 FeS cluster assembly K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 458.0
PYH2_k127_7430677_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 334.0
PYH2_k127_7430677_4 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008441 289.0
PYH2_k127_7430677_5 Uncharacterized protein family UPF0016 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009174 278.0
PYH2_k127_7430677_6 PFAM ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002127 268.0
PYH2_k127_7430677_7 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007701 268.0
PYH2_k127_7430677_8 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000005122 194.0
PYH2_k127_7435142_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 6.236e-214 672.0
PYH2_k127_7435142_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000006103 252.0
PYH2_k127_7435142_2 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001874 252.0
PYH2_k127_7435142_3 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K13566 - 3.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000005612 232.0
PYH2_k127_7435142_4 Belongs to the peptidase S8 family K14645 - - 0.0000000000000000000000000000000000000000000002293 195.0
PYH2_k127_7435142_5 DUF167 K09131 - - 0.000000000004491 70.0
PYH2_k127_7435142_6 chlorophyll binding - - - 0.00000032 65.0
PYH2_k127_7461713_0 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 456.0
PYH2_k127_7461713_1 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005192 368.0
PYH2_k127_7461713_2 Major facilitator Superfamily K08223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 364.0
PYH2_k127_7461713_3 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852,K00856 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004001,GO:0005488,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0005975,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032552,GO:0032553,GO:0032554,GO:0032555,GO:0032559,GO:0032560,GO:0032561,GO:0032567,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046390,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.15,2.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 331.0
PYH2_k127_7461713_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000001018 170.0
PYH2_k127_7461713_5 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000000000000000001745 125.0
PYH2_k127_7461713_6 - - - - 0.000000000000000000000000000007326 126.0
PYH2_k127_7465891_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 1.041e-249 780.0
PYH2_k127_7465891_1 prohibitin homologues - - - 0.0000000000000000000000000434 109.0
PYH2_k127_7465891_2 lipolytic protein G-D-S-L family - - - 0.0000000000001404 82.0
PYH2_k127_752277_0 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity K03583 - 3.1.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 547.0
PYH2_k127_752277_1 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582 - 3.1.11.5 0.000000000000000000000000000000000000000000000004169 186.0
PYH2_k127_7524338_0 elongation factor Tu domain 2 protein K02355 - - 8.906e-241 764.0
PYH2_k127_7524338_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000005159 263.0
PYH2_k127_7524338_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000001169 125.0
PYH2_k127_7524338_3 PFAM response regulator receiver - - - 0.000000000000000000000000008727 114.0
PYH2_k127_7524338_4 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000007655 110.0
PYH2_k127_7524338_5 cyclic nucleotide-binding K10914 - - 0.00000000000000000001758 104.0
PYH2_k127_7532287_0 Anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1075.0
PYH2_k127_7532287_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000052 473.0
PYH2_k127_7532287_2 Elongator protein 3, MiaB family, Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 442.0
PYH2_k127_7532287_3 SMART Tetratricopeptide - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 366.0
PYH2_k127_7532287_4 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 326.0
PYH2_k127_7532287_5 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000004327 257.0
PYH2_k127_7532287_6 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000001568 212.0
PYH2_k127_7532287_7 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.0000000000000000000000000000006229 126.0
PYH2_k127_7532287_8 - - - - 0.00000000000001833 75.0
PYH2_k127_7532287_9 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000006049 68.0
PYH2_k127_7533576_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 604.0
PYH2_k127_7533576_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000343 263.0
PYH2_k127_7533576_2 phosphorelay signal transduction system - - - 0.000000000000000000000000000009584 129.0
PYH2_k127_7533576_3 Thioredoxin - - - 0.0000000000000000000008259 100.0
PYH2_k127_7533576_4 Thioredoxin - - - 0.000000000000000000001488 95.0
PYH2_k127_7533576_5 - - - - 0.000000000000003003 78.0
PYH2_k127_7544194_0 Sulfatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009215 276.0
PYH2_k127_7544194_1 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000006959 156.0
PYH2_k127_7544194_2 TIGRFAM glutaredoxin-like domain protein - - - 0.0000000000000000000000000000000003577 139.0
PYH2_k127_7544194_3 alkyl hydroperoxide reductase activity - - - 0.0000000003295 63.0
PYH2_k127_7544194_4 alginic acid biosynthetic process - - - 0.000000001489 63.0
PYH2_k127_7544194_5 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.00005869 48.0
PYH2_k127_7546359_0 Belongs to the GARS family K01945 - 6.3.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003856 556.0
PYH2_k127_7546359_1 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004272 539.0
PYH2_k127_7546359_2 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000001559 154.0
PYH2_k127_7562927_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007652 559.0
PYH2_k127_7562927_1 sulfate adenylyltransferase K00958 - 2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 478.0
PYH2_k127_7562927_10 COG3209 Rhs family protein - - - 0.0002269 53.0
PYH2_k127_7562927_2 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007876 384.0
PYH2_k127_7562927_3 Catalyzes the synthesis of activated sulfate K00390,K00860,K00958,K13811 GO:0000096,GO:0000103,GO:0003674,GO:0003824,GO:0004020,GO:0004779,GO:0004781,GO:0006082,GO:0006520,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010134,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0019379,GO:0019419,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0055114,GO:0070566,GO:0071704,GO:1901564 1.8.4.10,1.8.4.8,2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000007986 248.0
PYH2_k127_7562927_5 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000001349 182.0
PYH2_k127_7562927_6 Peptidase family M48 - - - 0.00000000000000000000000000000000000125 152.0
PYH2_k127_7562927_7 ubiE/COQ5 methyltransferase family - - - 0.0000000000001001 82.0
PYH2_k127_7562927_8 L,D-transpeptidase catalytic domain - - - 0.000000000001493 70.0
PYH2_k127_7562927_9 SH3 domain - - - 0.00000006681 64.0
PYH2_k127_7604244_0 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001325 273.0
PYH2_k127_7604244_1 Belongs to the AAA ATPase family K13525 - - 0.00000000000000000000000000000000000000000000004379 182.0
PYH2_k127_7604244_2 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000000000000001227 173.0
PYH2_k127_7604244_3 Proteasomal ATPase OB/ID domain K07184,K07777,K12065,K13525,K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 2.7.13.3 0.0000000000000000000002477 96.0
PYH2_k127_7645809_0 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 549.0
PYH2_k127_7645809_1 iron ion homeostasis K03709,K04758 - - 0.00000000000000000000000000000000000000006683 156.0
PYH2_k127_7645809_2 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000003371 90.0
PYH2_k127_7658342_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006022,GO:0006023,GO:0006024,GO:0006807,GO:0008150,GO:0008152,GO:0008963,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0030203,GO:0034645,GO:0040007,GO:0042546,GO:0042802,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044249,GO:0044260,GO:0044464,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.8.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 444.0
PYH2_k127_7658342_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 383.0
PYH2_k127_7658342_2 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009277 346.0
PYH2_k127_7658342_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000142 283.0
PYH2_k127_7658342_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000005437 256.0
PYH2_k127_7677819_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1173.0
PYH2_k127_7677819_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009141 449.0
PYH2_k127_7677819_2 PhoH-like protein K06217 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 358.0
PYH2_k127_7677819_3 Diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.0000000000000000000000000000000000000000000000000000001514 205.0
PYH2_k127_7677819_4 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000000000001286 203.0
PYH2_k127_7677819_5 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.000000000000000000000000000000000000003549 147.0
PYH2_k127_7677819_6 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K03474,K03595,K07042 GO:0000469,GO:0000478,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005488,GO:0006139,GO:0006355,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016072,GO:0016151,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0019219,GO:0019222,GO:0019538,GO:0022613,GO:0030490,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043244,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.6.99.2,3.5.4.5 0.0000000000000000003915 96.0
PYH2_k127_771662_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1124.0
PYH2_k127_771662_1 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000007735 247.0
PYH2_k127_771662_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000000000000000000000000000000000004556 211.0
PYH2_k127_771662_3 4 iron, 4 sulfur cluster binding K00124 GO:0005575,GO:0005623,GO:0009326,GO:0032991,GO:0042597,GO:0044464,GO:1902494 - 0.000000000000000000000000000000000000000000000000005427 185.0
PYH2_k127_7723644_0 domain protein - - - 0.000000000000000000000000000000000000000000000000001321 198.0
PYH2_k127_7723644_1 - - - - 0.0000000000000000000000000000000000000000000000009747 188.0
PYH2_k127_7723644_2 - - - - 0.00000000000000000000000000000000000000000000005947 187.0
PYH2_k127_7723644_3 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000269 178.0
PYH2_k127_7723644_4 alginic acid biosynthetic process - - - 0.0000000000000000000000000000000000000000003631 169.0
PYH2_k127_7723644_5 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.00000000000000000000000000000348 129.0
PYH2_k127_7723644_6 - - - - 0.000000000000000000001985 104.0
PYH2_k127_7738696_0 glutamine synthetase, type I K01915 - 6.3.1.2 1.399e-208 659.0
PYH2_k127_7738696_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046040,GO:0046085,GO:0046086,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000421 501.0
PYH2_k127_7738696_10 FecR protein - - - 0.00000000007463 72.0
PYH2_k127_7738696_11 HEPN domain - - - 0.0000005005 59.0
PYH2_k127_7738696_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 335.0
PYH2_k127_7738696_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000001157 232.0
PYH2_k127_7738696_4 PFAM Appr-1-p processing domain protein - - - 0.000000000000000000000000000000000000000000000000000000007667 206.0
PYH2_k127_7738696_5 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000001177 201.0
PYH2_k127_7738696_6 Papain family cysteine protease - - - 0.00000000000000000000000000000000000000000000000612 183.0
PYH2_k127_7738696_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000001148 134.0
PYH2_k127_7738696_8 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000001539 119.0
PYH2_k127_7738696_9 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000102 81.0
PYH2_k127_7770105_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 507.0
PYH2_k127_7770105_1 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 441.0
PYH2_k127_7770105_2 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 332.0
PYH2_k127_7770105_3 LppC putative lipoprotein K07121 - - 0.0000000000000000000000000000000000000000000000000001316 208.0
PYH2_k127_7770105_4 Tetratricopeptide repeats - - - 0.00000000000000000000000000000000000000000000002184 196.0
PYH2_k127_7770105_5 Biotin/lipoate A/B protein ligase family K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.00000003455 59.0
PYH2_k127_7785015_0 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000008447 205.0
PYH2_k127_7785015_1 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000001414 179.0
PYH2_k127_7785015_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000001275 162.0
PYH2_k127_7785015_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000002268 119.0
PYH2_k127_7785015_4 Pfam Adenylate and Guanylate cyclase catalytic domain K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000009782 94.0
PYH2_k127_7785015_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858,K14652 GO:0003674,GO:0003824,GO:0003933,GO:0003935,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0019238,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.5.4.25,4.1.99.12 0.000001943 49.0
PYH2_k127_7792854_0 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 563.0
PYH2_k127_7792854_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 335.0
PYH2_k127_7792854_2 PFAM ResB family protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001672 291.0
PYH2_k127_7792854_3 heat shock protein binding - - - 0.000000000007603 71.0
PYH2_k127_7792854_4 Domain of unknown function (DUF4369) - - - 0.00001194 55.0
PYH2_k127_784647_0 PFAM permease YjgP YjgQ family protein K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007732 254.0
PYH2_k127_784647_1 Permease YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000002101 240.0
PYH2_k127_784647_2 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000003298 162.0
PYH2_k127_784647_3 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000005512 153.0
PYH2_k127_784647_4 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000201 145.0
PYH2_k127_7853969_0 Bacterial membrane protein YfhO - - - 0.0000000000000000000000000000000000002078 162.0
PYH2_k127_788603_0 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 2.606e-201 647.0
PYH2_k127_788603_1 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002101 482.0
PYH2_k127_788603_2 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 484.0
PYH2_k127_7907149_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1052.0
PYH2_k127_7907149_1 Lipopolysaccharide-assembly - - - 0.000000000001389 75.0
PYH2_k127_7907149_2 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.0000000004067 69.0
PYH2_k127_7932504_0 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000002698 142.0
PYH2_k127_7932504_1 L,D-transpeptidase catalytic domain - - - 0.000000000000000001552 93.0
PYH2_k127_7932504_2 - - - - 0.0000000000004182 77.0
PYH2_k127_7932504_3 RF-1 domain - - - 0.000000000145 64.0
PYH2_k127_7995066_0 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000133 281.0
PYH2_k127_7995066_1 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.000000000000000000000000000000000000000000000000000002949 207.0
PYH2_k127_7995066_2 Psort location CytoplasmicMembrane, score - - - 0.0000000000000000000001023 109.0
PYH2_k127_7996956_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.496e-194 628.0
PYH2_k127_7996956_1 Tyrosine recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009332 286.0
PYH2_k127_7996956_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000002419 197.0
PYH2_k127_7996956_3 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000001046 120.0
PYH2_k127_7996956_4 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.000000000000000000000001224 107.0
PYH2_k127_7996956_5 Protein of unknown function (DUF507) K09804 - - 0.00000000000000002522 85.0
PYH2_k127_7996956_6 Protein of unknown function (DUF507) - - - 0.0000001287 57.0
PYH2_k127_8002037_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 514.0
PYH2_k127_8002037_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 411.0
PYH2_k127_8002037_10 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000001554 79.0
PYH2_k127_8002037_11 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000001216 64.0
PYH2_k127_8002037_2 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 382.0
PYH2_k127_8002037_3 Bacillithiol biosynthesis BshC K22136 - - 0.000000000000000000000000000000000000000000000000000000002258 220.0
PYH2_k127_8002037_4 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00000000000000000000000000000000000000000000000000000007425 203.0
PYH2_k127_8002037_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000007974 124.0
PYH2_k127_8002037_6 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000001411 124.0
PYH2_k127_8002037_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000001251 131.0
PYH2_k127_8002037_8 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000001731 120.0
PYH2_k127_8002037_9 GlcNAc-PI de-N-acetylase - - - 0.0000000000000000000002614 100.0
PYH2_k127_8017279_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.626e-198 625.0
PYH2_k127_8017279_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006009 391.0
PYH2_k127_8017279_10 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000001679 174.0
PYH2_k127_8017279_11 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000000000001425 169.0
PYH2_k127_8017279_12 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000003406 152.0
PYH2_k127_8017279_13 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000001126 148.0
PYH2_k127_8017279_14 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.000000000000000000000000000000000005534 137.0
PYH2_k127_8017279_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000003229 104.0
PYH2_k127_8017279_16 Ribosomal protein L36 K02919 - - 0.00000000000002691 72.0
PYH2_k127_8017279_17 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000002579 67.0
PYH2_k127_8017279_18 Ribosomal protein L30 K02907 - - 0.0000000002721 69.0
PYH2_k127_8017279_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 322.0
PYH2_k127_8017279_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001451 282.0
PYH2_k127_8017279_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
PYH2_k127_8017279_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008228 269.0
PYH2_k127_8017279_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000154 220.0
PYH2_k127_8017279_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000009909 205.0
PYH2_k127_8017279_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0000027,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001313 208.0
PYH2_k127_8017279_9 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000005171 183.0
PYH2_k127_8071258_0 Arginosuccinate synthase K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 510.0
PYH2_k127_8071258_1 TIGRFAM argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 477.0
PYH2_k127_8095922_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007069 350.0
PYH2_k127_8095922_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 310.0
PYH2_k127_8095922_2 ADP-ribosylation factor family K06883 - - 0.000000000000000000000000000000000000000000000000000000000000000001377 233.0
PYH2_k127_8095922_3 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000005933 213.0
PYH2_k127_8095922_4 Tetratricopeptide repeat - - - 0.0000000000003006 81.0
PYH2_k127_8095922_6 FecR protein - - - 0.00009991 55.0
PYH2_k127_8142182_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005278 530.0
PYH2_k127_8142182_1 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 297.0
PYH2_k127_8142182_2 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000002199 234.0
PYH2_k127_8142182_3 - - - - 0.0000002285 57.0
PYH2_k127_8212579_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 583.0
PYH2_k127_8212579_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000958 306.0
PYH2_k127_8212579_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009595 259.0
PYH2_k127_8212579_3 Parallel beta-helix repeats - - - 0.0000001337 65.0
PYH2_k127_8212579_4 Calcineurin-like phosphoesterase - - - 0.000001223 62.0
PYH2_k127_8212579_6 - - - - 0.000002018 52.0
PYH2_k127_8225067_0 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 473.0
PYH2_k127_8225067_1 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 451.0
PYH2_k127_8225067_2 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006202 406.0
PYH2_k127_8225067_3 PFAM ABC transporter related K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009918 333.0
PYH2_k127_8225067_4 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009094 347.0
PYH2_k127_8225067_5 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 325.0
PYH2_k127_8225067_6 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K13503 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000109 252.0
PYH2_k127_8225067_7 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000161 220.0
PYH2_k127_8225067_8 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000005307 168.0
PYH2_k127_8225067_9 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000007281 101.0
PYH2_k127_8258467_0 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 296.0
PYH2_k127_8258467_1 Glycosyl transferase family 2 K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002983 257.0
PYH2_k127_8258467_2 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002495 243.0
PYH2_k127_8258467_3 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000101 92.0
PYH2_k127_8264070_0 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009562 284.0
PYH2_k127_8264070_1 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001095 312.0
PYH2_k127_8264070_2 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000000000000000000000000000000004285 157.0
PYH2_k127_8266651_2 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016465,GO:0018995,GO:0020003,GO:0023051,GO:0023056,GO:0030430,GO:0032991,GO:0033643,GO:0033646,GO:0033655,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0051082,GO:0061077,GO:0065007,GO:0065010,GO:0101031,GO:1901222,GO:1901224,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.0000000000000000001387 93.0
PYH2_k127_8266651_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000001291 73.0
PYH2_k127_8266651_4 Catalyzes the reduction of the disulfide bonds in the heme binding site of apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.0000000002833 73.0
PYH2_k127_8266651_5 Hep Hag repeat protein - - - 0.000000005001 68.0
PYH2_k127_8266651_6 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00002281 51.0
PYH2_k127_8266651_7 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0001479 46.0
PYH2_k127_8341258_0 PFAM Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000004129 207.0
PYH2_k127_8341258_1 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000136 201.0
PYH2_k127_8360226_0 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 356.0
PYH2_k127_8360226_1 TIGRFAM acyl-CoA thioester hydrolase, YbgC YbaW family K07107 - - 0.00000000000000000000000000000000000000000000000003192 182.0
PYH2_k127_8360226_2 PFAM metallophosphoesterase K07098 - - 0.0000002489 58.0
PYH2_k127_8365286_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.559e-274 862.0
PYH2_k127_8365286_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001589 339.0
PYH2_k127_8365286_10 Belongs to the UPF0109 family K06960 - - 0.000000000000000000000000001891 114.0
PYH2_k127_8365286_11 Domain of unknown function (DUF4349) - - - 0.0000002421 59.0
PYH2_k127_8365286_12 Domain of unknown function (DUF4340) - - - 0.00006038 55.0
PYH2_k127_8365286_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000008353 245.0
PYH2_k127_8365286_3 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000001261 222.0
PYH2_k127_8365286_4 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000002231 231.0
PYH2_k127_8365286_5 Histidine kinase K07651 - 2.7.13.3 0.00000000000000000000000000000000000000000000000001528 201.0
PYH2_k127_8365286_6 ECF sigma factor K03088 - - 0.000000000000000000000000000000000001346 148.0
PYH2_k127_8365286_7 metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000008466 137.0
PYH2_k127_8365286_8 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.0000000000000000000000000000009727 130.0
PYH2_k127_8365286_9 endoribonuclease - - - 0.00000000000000000000000000005272 121.0
PYH2_k127_8372290_0 General secretory system II, protein E domain protein K02652 - - 8.855e-221 699.0
PYH2_k127_8372290_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 558.0
PYH2_k127_8372290_2 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 491.0
PYH2_k127_8372290_3 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 382.0
PYH2_k127_8372290_4 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 316.0
PYH2_k127_8372290_5 Mur ligase, middle domain protein K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000004576 263.0
PYH2_k127_8372290_6 Adenosine specific kinase K09129 - - 0.00000000000000000000000000000000000000000000000000000000000000003246 226.0
PYH2_k127_8372290_7 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000004958 197.0
PYH2_k127_8372290_8 Transcriptional regulator, Crp Fnr family K10914 - - 0.0000000000000000000000000000000004483 147.0
PYH2_k127_8372290_9 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.0000000000000000000000001803 110.0
PYH2_k127_8383432_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 311.0
PYH2_k127_8383432_1 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001013 271.0
PYH2_k127_8383432_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000002771 214.0
PYH2_k127_8383432_3 Tetratricopeptide repeat - - - 0.0000000000000425 86.0
PYH2_k127_8400630_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 399.0
PYH2_k127_8400630_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 295.0
PYH2_k127_8400630_10 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000007814 65.0
PYH2_k127_8400630_11 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000001283 66.0
PYH2_k127_8400630_2 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001698 248.0
PYH2_k127_8400630_3 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0000027,GO:0000049,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000004299 207.0
PYH2_k127_8400630_4 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000000000000000000000000000000000000000000000465 196.0
PYH2_k127_8400630_5 Involved in the binding of tRNA to the ribosomes K02946 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000009368 177.0
PYH2_k127_8400630_6 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000004266 150.0
PYH2_k127_8400630_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000001572 132.0
PYH2_k127_8400630_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000001047 117.0
PYH2_k127_8400630_9 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000001325 112.0
PYH2_k127_8484581_0 Curli production assembly transport component CsgG - - - 0.00000000000000000000000000000000000000000001295 177.0
PYH2_k127_8484581_1 Protein of unknown function (DUF975) - - - 0.000000000000000000000000000000000000002431 157.0
PYH2_k127_8484581_2 - - - - 0.0000000000000009401 87.0
PYH2_k127_8508468_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 2.395e-218 689.0
PYH2_k127_8508468_1 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 459.0
PYH2_k127_8508468_2 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000001517 225.0
PYH2_k127_8508468_3 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000001047 176.0
PYH2_k127_8508468_4 4Fe-4S dicluster domain - - - 0.0000000000000000003997 96.0
PYH2_k127_8531445_0 TIGRFAM cysteine K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008223 398.0
PYH2_k127_8531445_1 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000000002061 133.0
PYH2_k127_8534612_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0 1037.0
PYH2_k127_8534612_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 477.0
PYH2_k127_8534612_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007164 382.0
PYH2_k127_8534612_3 PFAM ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005945 324.0
PYH2_k127_8534612_4 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002185 273.0
PYH2_k127_8534612_5 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000136 133.0
PYH2_k127_858582_0 epimerase dehydratase K01710,K01784 - 4.2.1.46,5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 496.0
PYH2_k127_858582_1 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 465.0
PYH2_k127_858582_10 COG3209 Rhs family protein - GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0004549,GO:0006139,GO:0006399,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016078,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:0140101,GO:1901360,GO:1901361,GO:1901575 - 0.0001129 55.0
PYH2_k127_858582_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 399.0
PYH2_k127_858582_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 366.0
PYH2_k127_858582_4 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 350.0
PYH2_k127_858582_5 UDP binding domain K02472 - 1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 341.0
PYH2_k127_858582_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000003437 235.0
PYH2_k127_858582_7 Glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000002612 193.0
PYH2_k127_858582_8 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000001643 97.0
PYH2_k127_858582_9 Parallel beta-helix repeats - - - 0.00000000000000001122 97.0
PYH2_k127_8618266_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007477 287.0
PYH2_k127_8618266_1 Subtilase family K01342 - 3.4.21.62 0.000000000000000000000000000000000000000000000000000000000000000000000000003471 272.0
PYH2_k127_8618266_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0030312,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000003926 201.0
PYH2_k127_8618266_3 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000001651 160.0
PYH2_k127_8618266_4 PFAM MazG nucleotide pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.0000000000000000000000000000000000031 140.0
PYH2_k127_8618266_5 Pyridoxamine 5'-phosphate oxidase - - - 0.0000000000000000000000000000938 123.0
PYH2_k127_8618266_6 Domain of unknown function (DUF1844) - - - 0.0000000000000000002224 93.0
PYH2_k127_8618266_7 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000003362 89.0
PYH2_k127_8639513_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002544 286.0
PYH2_k127_8639513_1 tRNA pseudouridine synthase activity K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000008432 265.0
PYH2_k127_8639513_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000004394 218.0
PYH2_k127_8639513_3 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000000001071 129.0
PYH2_k127_8639513_4 peptidase - - - 0.000000000000000000000000006293 124.0
PYH2_k127_8639513_6 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000004761 53.0
PYH2_k127_8639513_7 - - - - 0.00001082 53.0
PYH2_k127_8652748_0 DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 444.0
PYH2_k127_8652748_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 370.0
PYH2_k127_8652748_2 Cytidylate kinase-like family K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000526 246.0
PYH2_k127_8652748_3 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000001372 251.0
PYH2_k127_8652748_4 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000736 192.0
PYH2_k127_8652748_5 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000001385 132.0
PYH2_k127_8652748_6 Glycosyl transferase family 41 K09667 - 2.4.1.255 0.000000000000000000000001667 120.0
PYH2_k127_8652748_7 TonB C terminal K03646,K03832 - - 0.0000000001271 67.0
PYH2_k127_8652748_8 Alternative locus ID - - - 0.0000005474 60.0
PYH2_k127_8668039_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.697e-219 686.0
PYH2_k127_8668039_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002791 419.0
PYH2_k127_8668039_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002938 272.0
PYH2_k127_8668039_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000001233 207.0
PYH2_k127_8668039_4 PFAM amino acid-binding ACT domain protein - - - 0.0000000000000000000000000000000000000000000000000000001352 203.0
PYH2_k127_8668039_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000001977 108.0
PYH2_k127_8676390_0 Ribonuclease E/G family K08301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 532.0
PYH2_k127_8676390_1 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003245 251.0
PYH2_k127_8730957_0 Domain of unknown function (DUF1998) K06877 - - 1.128e-226 725.0
PYH2_k127_8730957_1 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K02768,K08483,K11183 - 2.7.1.202,2.7.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 582.0
PYH2_k127_8730957_2 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007223 278.0
PYH2_k127_8730957_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000000000000000004078 172.0
PYH2_k127_8730957_4 Exonuclease K07502 - - 0.0000000000000000000000000000000000000000005421 175.0
PYH2_k127_8730957_5 Extracellular repeat protein, HAF family - - - 0.000000000000000000000000000000000000000004571 168.0
PYH2_k127_8730957_6 system, mannose fructose sorbose family, IID component K02796 - - 0.0000000000000000000004111 110.0
PYH2_k127_8730957_7 Phosphocarrier protein HPr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000519 93.0
PYH2_k127_8730957_8 PTS system sorbose-specific iic component K02795,K19508 - - 0.000111 51.0
PYH2_k127_8738752_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.389e-227 723.0
PYH2_k127_8738752_1 PFAM MCP methyltransferase, CheR-type K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 309.0
PYH2_k127_8738752_2 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000001303 150.0
PYH2_k127_8738752_3 Two component signalling adaptor domain K03408 - - 0.0000000000000000002864 96.0
PYH2_k127_8745641_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.649e-250 812.0
PYH2_k127_8745641_1 lyase activity - - - 0.00000000000000000000000000000000000000000000000007869 186.0
PYH2_k127_8745641_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000001172 196.0
PYH2_k127_8745641_3 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000008616 190.0
PYH2_k127_8745641_4 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000005951 175.0
PYH2_k127_8745641_5 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000007383 161.0
PYH2_k127_8745641_6 PFAM PpiC-type peptidyl-prolyl cis-trans isomerase K03769,K07533 - 5.2.1.8 0.0000000000000000000004792 108.0
PYH2_k127_8762700_0 acetyl-CoA hydrolase transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005765 608.0
PYH2_k127_8762700_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 298.0
PYH2_k127_8762700_2 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004557 281.0
PYH2_k127_8762700_3 thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001222 264.0
PYH2_k127_8762700_4 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000003546 217.0
PYH2_k127_8762700_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000001449 202.0
PYH2_k127_8762700_6 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000001043 171.0
PYH2_k127_876332_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 604.0
PYH2_k127_876332_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 588.0
PYH2_k127_876332_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000002278 108.0
PYH2_k127_876332_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0003718 44.0
PYH2_k127_876332_4 hsp70-Hsp90 organizing protein K09553 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009409,GO:0009611,GO:0009628,GO:0009987,GO:0010033,GO:0016043,GO:0022607,GO:0031072,GO:0033554,GO:0034605,GO:0034622,GO:0035966,GO:0042221,GO:0043933,GO:0044085,GO:0050896,GO:0051131,GO:0051716,GO:0051879,GO:0065003,GO:0070417,GO:0070678,GO:0071840 - 0.0007801 47.0
PYH2_k127_8763906_0 SMART Tetratricopeptide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005446 338.0
PYH2_k127_8763906_1 PFAM ketose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007809 280.0
PYH2_k127_8763906_2 GAF domain - - - 0.00000000000000000000000000000000000000000002579 171.0
PYH2_k127_8763906_3 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000001985 110.0
PYH2_k127_8763906_4 lactoylglutathione lyase activity K01759,K05606,K08234 - 4.4.1.5,5.1.99.1 0.0000000002284 66.0
PYH2_k127_8771995_0 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000222 281.0
PYH2_k127_8771995_1 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000004514 192.0
PYH2_k127_8771995_2 protein kinase activity K06915 - - 0.0000000000000000000000000000000000004451 143.0
PYH2_k127_8771995_3 Elongator protein 3, MiaB family, Radical SAM K01843 - 5.4.3.2 0.00000000000000000000000009012 114.0
PYH2_k127_8771995_4 AAA-like domain - - - 0.00000000001683 72.0
PYH2_k127_8771995_5 AAA-like domain - - - 0.00002604 56.0
PYH2_k127_8775817_0 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 308.0
PYH2_k127_8775817_1 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008633 284.0
PYH2_k127_8775817_2 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000008834 206.0
PYH2_k127_8775817_3 Two component signalling adaptor domain K03408 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006935,GO:0008150,GO:0009453,GO:0009605,GO:0040011,GO:0042221,GO:0042330,GO:0042333,GO:0044424,GO:0044444,GO:0044464,GO:0050896 - 0.00000000000005859 76.0
PYH2_k127_8779005_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 529.0
PYH2_k127_8779005_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 516.0
PYH2_k127_8779005_2 PFAM penicillin-binding protein transpeptidase K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 457.0
PYH2_k127_8779005_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000005257 174.0
PYH2_k127_8795046_0 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 374.0
PYH2_k127_8795046_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000004902 173.0
PYH2_k127_8795046_2 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.000000000000000000000000000000007516 136.0
PYH2_k127_8795046_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.0000000000000000000000000000001434 136.0
PYH2_k127_8795046_4 enoyl-CoA hydratase K01715 - 4.2.1.17 0.000000000000000000000000000001717 130.0
PYH2_k127_8795046_5 NAD+ binding K00022 - 1.1.1.35 0.000000000000000000002305 108.0
PYH2_k127_8795046_6 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000002377 100.0
PYH2_k127_8801560_0 CBS domain containing protein K00974 - 2.7.7.72 5.531e-222 719.0
PYH2_k127_8801560_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 582.0
PYH2_k127_8801560_10 deoxyhypusine monooxygenase activity - - - 0.0000000000000005884 91.0
PYH2_k127_8801560_2 TIGRFAM acetylornithine and succinylornithine K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 407.0
PYH2_k127_8801560_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008886 376.0
PYH2_k127_8801560_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 333.0
PYH2_k127_8801560_5 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.0000000000000000000000000000000000000000000000000004504 195.0
PYH2_k127_8801560_6 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000001633 184.0
PYH2_k127_8801560_7 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000001122 179.0
PYH2_k127_8801560_8 membrane organization K20543 - - 0.0000000000000000000000000000000000000000001489 166.0
PYH2_k127_8801560_9 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000004488 138.0
PYH2_k127_8906023_0 CheA signal transduction histidine K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 402.0
PYH2_k127_8906023_1 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000002079 169.0
PYH2_k127_8906023_2 peptidase M4 thermolysin K01399,K08604 GO:0005575,GO:0005576 3.4.24.25,3.4.24.26 0.0000000000000000000001853 110.0
PYH2_k127_8938849_0 PFAM glycosyl transferase family 39 K14340 - - 0.00000000000000000000000000000000000000000000000000000000000000002761 246.0
PYH2_k127_8938849_1 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000003766 78.0
PYH2_k127_8938849_2 Domain of unknown function (DUF1858) - - - 0.00000000003363 68.0
PYH2_k127_8955644_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003288 299.0
PYH2_k127_8955644_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001874 304.0
PYH2_k127_8955644_10 response to nickel cation K07722 - - 0.000000000000000017 84.0
PYH2_k127_8955644_11 Phage integrase, N-terminal SAM-like domain - - - 0.0000979 51.0
PYH2_k127_8955644_2 Lipocalin-like domain K03098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001212 259.0
PYH2_k127_8955644_3 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000003718 248.0
PYH2_k127_8955644_4 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000001702 228.0
PYH2_k127_8955644_5 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.000000000000000000000000000000000000000000000001326 176.0
PYH2_k127_8955644_6 Sulfatase - - - 0.00000000000000000000000000000000002287 147.0
PYH2_k127_8955644_7 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000001043 131.0
PYH2_k127_8955644_8 Glycosyltransferase family 9 (heptosyltransferase) K02841 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.0000000000000000000000000004247 126.0
PYH2_k127_8955644_9 copG family - - - 0.00000000000000000007866 91.0
PYH2_k127_8962581_0 Nitronate monooxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 524.0
PYH2_k127_8962581_1 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009712 351.0
PYH2_k127_8962581_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 349.0
PYH2_k127_8962581_3 heat shock protein DnaJ domain protein K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003548 310.0
PYH2_k127_8962581_4 Fic/DOC family K04095 - - 0.0000000000000000000000000000000000000000000000000000000000000001483 228.0
PYH2_k127_8962581_5 Belongs to the glycosyl hydrolase 31 family - - - 0.0000000000000000000000000000000000000000000000000000001294 202.0
PYH2_k127_8962581_6 RHS protein - - - 0.0000000000000000000000000000000003215 140.0
PYH2_k127_8962581_7 Regulatory protein, FmdB family - - - 0.0000000000317 65.0
PYH2_k127_8974368_0 AMP-binding enzyme K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 532.0
PYH2_k127_8974368_1 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 430.0
PYH2_k127_8974368_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000001822 262.0
PYH2_k127_8974368_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000002307 201.0
PYH2_k127_8974368_4 dehydratase - - - 0.000000000000000000000000000000001468 138.0
PYH2_k127_8974368_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000007772 117.0
PYH2_k127_8974368_6 PIN domain - - - 0.00000000000000000000000002484 114.0
PYH2_k127_8974368_7 MMPL family K07003 - - 0.000000000009902 69.0
PYH2_k127_8974368_8 - - - - 0.000000000167 64.0
PYH2_k127_8990206_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 559.0
PYH2_k127_8990206_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 415.0
PYH2_k127_8990206_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 303.0
PYH2_k127_8990206_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001601 260.0
PYH2_k127_8990206_4 Conserved repeat domain - - - 0.00000000000000000000000000000000000216 158.0
PYH2_k127_8990206_5 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000005829 124.0
PYH2_k127_8990206_6 Preprotein translocase subunit K03210 - - 0.0000000000000000000002158 100.0
PYH2_k127_8990206_7 cheY-homologous receiver domain - - - 0.00000000000000001864 87.0
PYH2_k127_8990206_8 Recombination protein O C terminal K03584 - - 0.00000000000001023 84.0
PYH2_k127_9031784_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000459 222.0
PYH2_k127_9031784_1 PFAM thioesterase superfamily protein - - - 0.00000000000000000000000000000000000000000000007997 173.0
PYH2_k127_9031784_2 TIGRFAM pyridoxal phosphate-dependent enzymes, D-cysteine desulfhydrase family K05396 - 4.4.1.15 0.0000000000000000000000000000000001517 134.0
PYH2_k127_9031784_3 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000004893 88.0
PYH2_k127_9031784_4 TOBE domain - - - 0.0000000000003057 72.0
PYH2_k127_9034062_0 cobalt ion transport K02007,K02009,K16915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006926 422.0
PYH2_k127_9034062_1 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 365.0
PYH2_k127_9034062_2 Cobalt transport protein K02008 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 295.0
PYH2_k127_9034062_3 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000008542 190.0
PYH2_k127_9034062_4 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000008565 158.0
PYH2_k127_9034062_5 FecR protein - - - 0.00000000000000000000000000000000001644 141.0
PYH2_k127_9034062_6 PBP superfamily domain K05772 - - 0.0000000000000000009194 93.0
PYH2_k127_9034062_7 - - - - 0.00000000000000156 84.0
PYH2_k127_9034062_8 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000004076 57.0
PYH2_k127_9034062_9 - - - - 0.00000156 56.0
PYH2_k127_9075197_0 Carbamoyltransferase C-terminus K00612 - - 5.926e-273 850.0
PYH2_k127_9075197_1 short-chain dehydrogenase reductase SDR K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002814 342.0
PYH2_k127_9075197_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000347 91.0
PYH2_k127_9075197_3 - - - - 0.00000000000000001088 88.0
PYH2_k127_9075197_4 - - - - 0.000000000000002162 77.0
PYH2_k127_9075197_5 - - - - 0.000000000000002919 86.0
PYH2_k127_9091547_0 Seven times multi-haem cytochrome CxxCH - - - 3.244e-205 649.0
PYH2_k127_9091547_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 435.0
PYH2_k127_9091547_10 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.00000000000000000000000000000000000000000000000000000468 197.0
PYH2_k127_9091547_11 Transglycosylase K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000003478 194.0
PYH2_k127_9091547_12 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000005558 189.0
PYH2_k127_9091547_13 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000002984 188.0
PYH2_k127_9091547_14 MgtC family K07507 - - 0.00000000000000000000000000000000000001924 152.0
PYH2_k127_9091547_15 - - - - 0.00000000000000000000000000000000000006687 145.0
PYH2_k127_9091547_16 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000223 153.0
PYH2_k127_9091547_17 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000002243 133.0
PYH2_k127_9091547_18 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000133 113.0
PYH2_k127_9091547_19 - - - - 0.0000000000000001687 88.0
PYH2_k127_9091547_2 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 430.0
PYH2_k127_9091547_20 - - - - 0.0000000000000008458 90.0
PYH2_k127_9091547_22 - - - - 0.0002795 52.0
PYH2_k127_9091547_23 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0003328 44.0
PYH2_k127_9091547_3 Peptidase U62 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 430.0
PYH2_k127_9091547_4 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 411.0
PYH2_k127_9091547_5 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886 - 1.1.1.276 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 321.0
PYH2_k127_9091547_6 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 287.0
PYH2_k127_9091547_7 von Willebrand factor type A domain K07114 - - 0.0000000000000000000000000000000000000000000000000000000008259 218.0
PYH2_k127_9091547_8 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000006718 205.0
PYH2_k127_9091547_9 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000001448 201.0
PYH2_k127_910622_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 395.0
PYH2_k127_910622_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 320.0
PYH2_k127_910622_10 PFAM regulatory protein AsnC Lrp family - - - 0.0000000000004509 76.0
PYH2_k127_910622_11 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000008204 57.0
PYH2_k127_910622_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005091 285.0
PYH2_k127_910622_3 PAS fold - - - 0.0000000000000000000000000000000000000003868 167.0
PYH2_k127_910622_4 Nitroreductase family - - - 0.0000000000000000000000000000000000006604 146.0
PYH2_k127_910622_5 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000000000000000000000172 141.0
PYH2_k127_910622_6 Belongs to the ParB family K03497 - - 0.000000000000000000000000000004233 123.0
PYH2_k127_910622_7 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000000004793 108.0
PYH2_k127_910622_8 Smr domain K07456 GO:0000018,GO:0008150,GO:0009892,GO:0010605,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0045910,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0060255,GO:0065007,GO:0080090 - 0.000000000000000000000003565 113.0
PYH2_k127_910622_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000000000000009368 86.0
PYH2_k127_9125954_0 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 521.0
PYH2_k127_9125954_1 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 382.0
PYH2_k127_9125954_2 RmuC family K09760 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003295 274.0
PYH2_k127_9125954_3 Secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000005622 218.0
PYH2_k127_9125954_4 SurA N-terminal domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000008504 221.0
PYH2_k127_9125954_5 Belongs to the helicase family. UvrD subfamily - - - 0.0000000000000000000000000000000000000000000000000000000001713 214.0
PYH2_k127_9125954_6 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000007296 181.0
PYH2_k127_9125954_7 phosphorelay signal transduction system - - - 0.0000000001739 69.0
PYH2_k127_9125954_8 NHL repeat - - - 0.000000004992 70.0
PYH2_k127_9125954_9 - - - - 0.00000001141 69.0
PYH2_k127_9133590_0 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 467.0
PYH2_k127_9133590_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 456.0
PYH2_k127_9133590_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000275 366.0
PYH2_k127_9133590_3 PFAM cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 312.0
PYH2_k127_9133590_4 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000001853 195.0
PYH2_k127_9133590_5 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000002165 96.0
PYH2_k127_9156896_0 PFAM peptidase - - - 0.0000000000000000000000000008051 128.0
PYH2_k127_9156896_1 membrane - - - 0.000000000000000000000000001744 118.0
PYH2_k127_9156896_2 Cold shock protein K03704 - - 0.00000000000000000000000006123 108.0
PYH2_k127_9156896_3 cellulase activity K20276 - - 0.0000000000002777 83.0
PYH2_k127_9156896_4 TIGRFAM polysaccharide pyruvyl transferase CsaB - - - 0.00000000005471 70.0
PYH2_k127_9156896_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000003951 59.0
PYH2_k127_9183490_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 449.0
PYH2_k127_9183490_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 387.0
PYH2_k127_9183490_10 Thiopurine S-methyltransferase (TPMT) - - - 0.0001753 53.0
PYH2_k127_9183490_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001405 259.0
PYH2_k127_9183490_3 (Rhomboid) family - - - 0.000000000000000000000000000000000000000000000000000000000000000002178 239.0
PYH2_k127_9183490_4 Ribosomal protein L11 methyltransferase (PrmA) K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000009827 213.0
PYH2_k127_9183490_5 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000002583 196.0
PYH2_k127_9183490_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000003813 188.0
PYH2_k127_9183490_7 protein methyltransferase activity K00568,K02687 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000006127 164.0
PYH2_k127_9183490_8 PFAM PHP domain protein K07053 - 3.1.3.97 0.00000000000000000000000000000000001801 145.0
PYH2_k127_9183490_9 polysaccharide biosynthetic process - - - 0.0000000000001998 83.0
PYH2_k127_9186629_0 AIR synthase related protein, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 461.0
PYH2_k127_9186629_1 Mur ligase middle domain K01925,K01932 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 328.0
PYH2_k127_9186629_2 Flavin containing amine oxidoreductase K09516,K09835 - 1.3.99.23,5.2.1.13 0.00000000000000000000000000000000000000000000001201 189.0
PYH2_k127_9186629_3 Thiamine-binding protein - - - 0.0000000000000000000000000000003587 137.0
PYH2_k127_9186629_4 Capsule biosynthesis CapC K22116 - - 0.0000000000000000003582 96.0
PYH2_k127_9186629_5 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP - - - 0.000000000000000001888 94.0
PYH2_k127_9186629_6 transferase K00997 - 2.7.8.7 0.0001663 49.0
PYH2_k127_9213203_0 Glutamine amidotransferases class-II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003086 496.0
PYH2_k127_9213203_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004237 336.0
PYH2_k127_9213203_2 Belongs to the glutamate synthase family - - - 0.0005217 52.0
PYH2_k127_9213737_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 610.0
PYH2_k127_9213737_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000002288 249.0
PYH2_k127_9213737_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.00000000000000000000000000000000000000000000000000005293 190.0
PYH2_k127_9213737_3 ABC transporter substrate binding protein K01989 - - 0.0000000000000007143 85.0
PYH2_k127_944225_0 oligosaccharyl transferase activity - - - 0.0000000000000000000000000000009763 139.0
PYH2_k127_944225_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000000002914 80.0