Overview

ID MAG03207
Name PYH2_bin.66
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Thermodesulfovibrionia
Order Thermodesulfovibrionales
Family UBA9159
Genus
Species
Assembly information
Completeness (%) 78.15
Contamination (%) 3.74
GC content (%) 52.0
N50 (bp) 5,762
Genome size (bp) 1,514,224

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1626

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1014992_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005616 422.0
PYH2_k127_1014992_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000007244 189.0
PYH2_k127_1014992_2 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000007431 188.0
PYH2_k127_1014992_3 lipopolysaccharide transmembrane transporter activity K03303,K07058 - - 0.00000002432 64.0
PYH2_k127_105066_0 competence protein - - - 0.00000000000000000000000000000000000000000001083 171.0
PYH2_k127_105066_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000001194 147.0
PYH2_k127_105066_2 - - - - 0.000000000000000001058 92.0
PYH2_k127_105066_3 Cytochrome C' - - - 0.0000004365 57.0
PYH2_k127_105066_4 Domain of unknown function (DUF4124) - - - 0.000008581 51.0
PYH2_k127_1055315_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.253e-318 993.0
PYH2_k127_1055315_1 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02481,K11384 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004183 437.0
PYH2_k127_1055315_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 308.0
PYH2_k127_1055315_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001958 265.0
PYH2_k127_1055315_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000006756 242.0
PYH2_k127_1055315_5 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000001905 155.0
PYH2_k127_1055315_6 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000002232 140.0
PYH2_k127_1055315_7 Response regulator receiver domain - - - 0.00000000001397 69.0
PYH2_k127_1057908_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 610.0
PYH2_k127_1057908_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 439.0
PYH2_k127_1057908_2 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 356.0
PYH2_k127_1057908_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 351.0
PYH2_k127_1057908_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001015 289.0
PYH2_k127_1057908_5 MraZ protein, putative antitoxin-like K03925 - - 0.000000000000000000000000000000000000000000000000000002063 194.0
PYH2_k127_1057908_6 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000001134 117.0
PYH2_k127_1057908_8 Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000001519 62.0
PYH2_k127_109160_0 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 319.0
PYH2_k127_109160_1 Mo-molybdopterin cofactor metabolic process K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001129 264.0
PYH2_k127_109160_2 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001648 268.0
PYH2_k127_110558_0 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 374.0
PYH2_k127_110558_1 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 365.0
PYH2_k127_110558_2 von Willebrand factor (vWF) type A domain K02448 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004551 389.0
PYH2_k127_110558_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080,K14082 - 2.1.1.246,2.1.1.247,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003629 360.0
PYH2_k127_110558_4 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001492 251.0
PYH2_k127_110558_5 Predicted metal-binding protein (DUF2284) - - - 0.00000000000000000000000000000000000000000001303 170.0
PYH2_k127_110558_6 cobalamin synthesis protein - - - 0.00000000000000000000000000000000000000003914 159.0
PYH2_k127_110558_7 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000005128 136.0
PYH2_k127_110558_8 SCP-2 sterol transfer family - - - 0.0000000000000000008274 89.0
PYH2_k127_111616_0 phosphatidate phosphatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000008862 229.0
PYH2_k127_111616_1 PFAM response regulator receiver K02483,K18344 - - 0.000000000000000000000000000000000000000000000000000000000001711 215.0
PYH2_k127_111616_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000001312 144.0
PYH2_k127_111616_3 YacP-like NYN domain K06962 - - 0.00000000000000000000174 102.0
PYH2_k127_1125535_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 440.0
PYH2_k127_1125535_1 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 427.0
PYH2_k127_1125535_2 galactose-1-phosphate K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 368.0
PYH2_k127_1125535_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033,K15581 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002404 281.0
PYH2_k127_1125535_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001139 247.0
PYH2_k127_1125535_5 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001628 218.0
PYH2_k127_1125535_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000001738 211.0
PYH2_k127_1125535_7 PFAM ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000002799 136.0
PYH2_k127_1125535_8 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000000000000000000002726 128.0
PYH2_k127_1125535_9 Zinc dependent phospholipase C - - - 0.0000000005304 61.0
PYH2_k127_1138179_0 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001367 259.0
PYH2_k127_1138179_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000003496 255.0
PYH2_k127_1138179_2 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000001091 183.0
PYH2_k127_1138179_3 FabA-like domain K02372 - 4.2.1.59 0.0000000000000000000001536 102.0
PYH2_k127_1169594_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 4.355e-295 918.0
PYH2_k127_1169594_1 Protein of unknown function, DUF255 K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005776 241.0
PYH2_k127_1169594_2 - - - - 0.000000000000000000002878 94.0
PYH2_k127_1170155_0 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 363.0
PYH2_k127_1170155_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004827 344.0
PYH2_k127_117080_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.485e-299 931.0
PYH2_k127_117080_1 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 6.564e-268 843.0
PYH2_k127_117080_10 Thioredoxin-like domain K03671 - - 0.00000000000000000000000000000000000000006206 153.0
PYH2_k127_117080_11 - - - - 0.000000000000000000004336 97.0
PYH2_k127_117080_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 597.0
PYH2_k127_117080_3 acetyl-CoA catabolic process K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 513.0
PYH2_k127_117080_4 one-carbon metabolic process K00194,K00198 - 1.2.7.4,2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005816 378.0
PYH2_k127_117080_5 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 368.0
PYH2_k127_117080_6 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 355.0
PYH2_k127_117080_7 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001497 283.0
PYH2_k127_117080_8 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001054 275.0
PYH2_k127_117080_9 - - - - 0.000000000000000000000000000000000000000000000000003917 186.0
PYH2_k127_1172643_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003399 529.0
PYH2_k127_1172643_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 411.0
PYH2_k127_1176449_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 362.0
PYH2_k127_1176449_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 286.0
PYH2_k127_1176449_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000001299 202.0
PYH2_k127_1176449_3 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000002552 134.0
PYH2_k127_119186_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 396.0
PYH2_k127_119186_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 319.0
PYH2_k127_119186_2 YbbR-like protein - - - 0.00000000000000000000000000000000000001101 152.0
PYH2_k127_119186_3 Domain of unknown function (DUF4412) - - - 0.000000000000000000000000000000000002623 145.0
PYH2_k127_1195761_0 S-adenosylhomocysteine deaminase activity K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 475.0
PYH2_k127_1195761_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006346 256.0
PYH2_k127_1195761_2 HlyD family secretion protein - - - 0.000000000000000000000000000000000000000000000000000000006232 205.0
PYH2_k127_1195761_3 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000003682 196.0
PYH2_k127_119599_0 Phosphoglycerate kinase K00927 - 2.7.2.3 1.435e-204 642.0
PYH2_k127_119599_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005369 490.0
PYH2_k127_119599_2 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 477.0
PYH2_k127_119599_3 Calcineurin-like phosphoesterase K07098 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005714 409.0
PYH2_k127_119599_4 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000002834 207.0
PYH2_k127_119599_5 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000002288 197.0
PYH2_k127_119599_6 2'-5' RNA ligase superfamily - - - 0.00000000000003127 76.0
PYH2_k127_119599_7 ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0007058 43.0
PYH2_k127_127297_0 PFAM 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 392.0
PYH2_k127_127297_1 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001616 270.0
PYH2_k127_127297_2 Diguanylate cyclase K21084 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000006268 287.0
PYH2_k127_127297_3 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000000000000000000000000000000000000000000000000000000002384 216.0
PYH2_k127_1276061_0 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 337.0
PYH2_k127_1276061_1 Rieske [2Fe-2S] domain K02636 - 1.10.9.1 0.000000000000000000000000006521 115.0
PYH2_k127_1276061_2 protein complex oligomerization - - - 0.000000000000000000000002396 109.0
PYH2_k127_1276061_3 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000000003123 66.0
PYH2_k127_128886_0 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000001001 241.0
PYH2_k127_128886_1 lactate metabolic process K11473,K18928 - - 0.000000000000000000000000000000000000000000000000000000000000003745 231.0
PYH2_k127_128886_2 Molybdenum cofactor biosynthesis K03638,K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000005076 204.0
PYH2_k127_128886_3 PFAM MOSC domain - - - 0.00000000000000000000000000000000003125 135.0
PYH2_k127_128886_5 Regulatory protein, FmdB family - - - 0.000000000000000001075 87.0
PYH2_k127_1380061_0 S-layer homology domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 345.0
PYH2_k127_1380061_1 TPR repeat-containing protein - - - 0.000000000000000006821 92.0
PYH2_k127_1380061_2 COG0760 Parvulin-like peptidyl-prolyl isomerase - - - 0.0000000001973 70.0
PYH2_k127_1425252_0 Specifically catalyzes the beta-elimination of phosphate from L-phosphoserine and the beta-addition of sulfite to the dehydroalanine intermediate to produce L-cysteate K15527 - 2.5.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 370.0
PYH2_k127_1425252_1 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrD may act as the catalytic subunit K08264 GO:0003674,GO:0003824,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016491,GO:0016667,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 302.0
PYH2_k127_1425252_2 PFAM ABC transporter related K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001102 265.0
PYH2_k127_1425252_3 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.00000000000000000000000000000000001765 137.0
PYH2_k127_1425252_4 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K13039 - 4.1.1.79 0.00000000000000000000000002716 110.0
PYH2_k127_1425252_5 PFAM Nitrate reductase gamma subunit - - - 0.000000000000004909 83.0
PYH2_k127_1425252_6 - - - - 0.000000000000008309 80.0
PYH2_k127_1434732_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 468.0
PYH2_k127_1434732_1 PFAM HhH-GPD superfamily base excision DNA repair protein K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009963 294.0
PYH2_k127_1434732_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000005094 174.0
PYH2_k127_1434732_3 Rhodanese Homology Domain - - - 0.0000000000000000000000001087 111.0
PYH2_k127_1441307_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006708 292.0
PYH2_k127_1441307_1 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000001902 234.0
PYH2_k127_1441307_2 Domain of unknown function (DUF296) - - - 0.0000000000000000000000000000000000000000000000000000000003431 205.0
PYH2_k127_1441307_3 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000000009868 187.0
PYH2_k127_1441307_4 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0000000000000000000000000000000000000000000000001347 181.0
PYH2_k127_1441307_5 geranylgeranyl reductase activity K14266 - 1.14.19.9 0.0000000000000000000000000000000000000000004616 163.0
PYH2_k127_1441307_6 PFAM thioesterase superfamily K02614 - - 0.0000000000000007214 83.0
PYH2_k127_1460710_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001731 474.0
PYH2_k127_1460710_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 322.0
PYH2_k127_1460710_2 MgsA AAA+ ATPase C terminal K07478 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006325 270.0
PYH2_k127_1460710_3 Chemotaxis protein CheC, inhibitor of MCP methylation K03410 - - 0.000000000000000000000000000000000000000000000000000000000000000001929 234.0
PYH2_k127_1460710_4 Response regulator receiver - - - 0.00000000000000000000000000000003521 129.0
PYH2_k127_1460710_5 EamA-like transporter family - - - 0.000000000000000000000001251 114.0
PYH2_k127_1460710_6 photoreceptor activity - - - 0.00000000000004069 86.0
PYH2_k127_1472098_0 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002064 275.0
PYH2_k127_1472098_1 intermembrane phospholipid transfer K07323 - - 0.00000000000000000000000000000000000000000000006275 176.0
PYH2_k127_1472098_2 Endonuclease/Exonuclease/phosphatase family - - - 0.00000000000000000000000585 106.0
PYH2_k127_1472098_3 PIN domain - - - 0.0000000000000003374 85.0
PYH2_k127_1544729_0 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 317.0
PYH2_k127_1544729_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000116 116.0
PYH2_k127_1544729_2 - - - - 0.00000000000000000003836 97.0
PYH2_k127_1544729_3 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 0.00000000194 61.0
PYH2_k127_1544729_4 COG3547 Transposase and inactivated derivatives - - - 0.00000002158 58.0
PYH2_k127_159871_0 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 583.0
PYH2_k127_159871_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.0000000000000000000000000000000000001224 146.0
PYH2_k127_159871_2 Uncharacterized conserved protein (DUF2249) K07322 - - 0.0000000000000000000000000006029 115.0
PYH2_k127_159871_3 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000004479 104.0
PYH2_k127_159871_4 Domain of unknown function (DUF1858) - - - 0.000000000005028 68.0
PYH2_k127_1603707_0 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 447.0
PYH2_k127_1603707_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000006442 259.0
PYH2_k127_1603707_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005882 246.0
PYH2_k127_1603707_3 DivIVA protein K04074 - - 0.00000000000000000000000000000000000000000000000000000000000000002256 226.0
PYH2_k127_1603707_4 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000001699 170.0
PYH2_k127_1603707_5 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.0000000000000000000000000000000000000001239 162.0
PYH2_k127_1603707_6 YGGT family K02221 - - 0.000000000000000000000000000000000003847 139.0
PYH2_k127_1603707_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000001404 128.0
PYH2_k127_1615806_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 556.0
PYH2_k127_1615806_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 446.0
PYH2_k127_1615806_10 cyclic nucleotide-binding - - - 0.000000000000001185 83.0
PYH2_k127_1615806_2 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 345.0
PYH2_k127_1615806_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001804 275.0
PYH2_k127_1615806_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000005192 215.0
PYH2_k127_1615806_5 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000005806 197.0
PYH2_k127_1615806_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001043 194.0
PYH2_k127_1615806_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000001435 148.0
PYH2_k127_1615806_8 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000000000000005962 134.0
PYH2_k127_1615806_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000000005079 128.0
PYH2_k127_1620234_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001495 314.0
PYH2_k127_1620234_1 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000003092 221.0
PYH2_k127_1675039_0 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 595.0
PYH2_k127_1675039_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 589.0
PYH2_k127_1675039_2 elongation factor Tu domain 2 protein K06207 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003467 241.0
PYH2_k127_1675039_3 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000000472 202.0
PYH2_k127_1675039_4 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000007268 62.0
PYH2_k127_1747942_0 PhoH-like protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007934 399.0
PYH2_k127_1747942_1 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 334.0
PYH2_k127_1747942_2 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006175 262.0
PYH2_k127_1747942_3 PFAM Stage II sporulation K06381 - - 0.000000000000000000000000000000000000000000000000000000000000000000005673 250.0
PYH2_k127_1747942_4 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000001442 211.0
PYH2_k127_1747942_5 queuosine biosynthetic process K03470,K09765 - 1.17.99.6,3.1.26.4 0.0000000000000000000000000000000000000000000000000000001572 200.0
PYH2_k127_1747942_6 Protein of unknown function (DUF2905) - - - 0.000000000000000000005958 94.0
PYH2_k127_1747942_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000002679 87.0
PYH2_k127_1747942_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K01448,K02519 - 3.5.1.28 0.00001698 54.0
PYH2_k127_1761037_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 477.0
PYH2_k127_1761037_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 329.0
PYH2_k127_1761037_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000001182 245.0
PYH2_k127_177395_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1019.0
PYH2_k127_177395_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.441e-273 857.0
PYH2_k127_177395_2 Belongs to the peptidase M16 family - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 383.0
PYH2_k127_177395_3 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000006967 134.0
PYH2_k127_177395_4 Beta-eliminating lyase K04487 - 2.8.1.7 0.00000006636 55.0
PYH2_k127_1806723_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 364.0
PYH2_k127_1806723_1 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.0000000000000000000000000000002301 129.0
PYH2_k127_1806723_2 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000001029 114.0
PYH2_k127_1806723_3 - - - - 0.00000000000002087 83.0
PYH2_k127_1806723_5 nuclease K00590,K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 2.1.1.113,3.1.31.1 0.000007822 48.0
PYH2_k127_1806723_6 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins K02461 - - 0.0002384 53.0
PYH2_k127_1819257_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 557.0
PYH2_k127_1819257_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 347.0
PYH2_k127_1819257_2 COG1194 A G-specific DNA glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 295.0
PYH2_k127_1819257_3 PFAM Phosphomethylpyrimidine kinase type-1 K00868,K00941,K14153 - 2.5.1.3,2.7.1.35,2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000006023 230.0
PYH2_k127_1819257_4 Helix-turn-helix domain - - - 0.000000000000000000002185 103.0
PYH2_k127_1819257_5 - - - - 0.00001286 55.0
PYH2_k127_1823232_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 384.0
PYH2_k127_1823232_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018065,GO:0018130,GO:0018160,GO:0018193,GO:0018198,GO:0019438,GO:0019538,GO:0033013,GO:0033014,GO:0034641,GO:0036211,GO:0042168,GO:0042440,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.00000000000000000000000000000000000000000000006773 173.0
PYH2_k127_1823232_2 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000001505 154.0
PYH2_k127_1837206_0 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000002138 241.0
PYH2_k127_1837206_1 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000001568 143.0
PYH2_k127_1837206_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000001263 90.0
PYH2_k127_1837206_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000001601 59.0
PYH2_k127_1868972_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006858 492.0
PYH2_k127_1868972_1 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 413.0
PYH2_k127_1868972_2 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000000000000000000000354 145.0
PYH2_k127_1926402_0 DegT/DnrJ/EryC1/StrS aminotransferase family K14260 - 2.6.1.2,2.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000394 234.0
PYH2_k127_1926402_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000009041 222.0
PYH2_k127_1926402_2 ferrous iron binding K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000004348 211.0
PYH2_k127_1926402_3 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000001169 94.0
PYH2_k127_1926402_4 heat shock protein binding - - - 0.0000000000000335 86.0
PYH2_k127_1926402_7 Tetratricopeptide repeat - - - 0.0008539 52.0
PYH2_k127_1930680_0 4Fe-4S binding domain - - - 2.142e-227 714.0
PYH2_k127_1930680_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000003237 221.0
PYH2_k127_1930680_2 Adenylylsulphate kinase K00860 - 2.7.1.25 0.00000000000000000000000000000000000000007724 156.0
PYH2_k127_1930680_3 Domain of unknown function (DUF362) - - - 0.0000009448 51.0
PYH2_k127_1932159_0 ATP synthase alpha/beta family, nucleotide-binding domain K02118 - - 5.082e-198 627.0
PYH2_k127_1932159_1 Phosphoglycerate kinase K00927 - 2.7.2.3 5.434e-194 613.0
PYH2_k127_1932159_2 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000001876 197.0
PYH2_k127_1932159_3 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000148 129.0
PYH2_k127_1968694_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 3.409e-267 835.0
PYH2_k127_1968694_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005599 584.0
PYH2_k127_1968694_2 (Rhomboid) family K07059 - - 0.00000000000000000000000000000000000000000000000000000000000000002604 230.0
PYH2_k127_1968694_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K18330 - 1.12.1.3 0.0000000000000000000000000000000000000000000000000004021 190.0
PYH2_k127_1968694_4 Ferredoxin K17992 - 1.12.1.3 0.000000000000000000000000000000000000000006924 159.0
PYH2_k127_1968694_5 zinc-ribbon domain - - - 0.00000000000000000000000000000000000000003473 162.0
PYH2_k127_196954_0 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008939 295.0
PYH2_k127_196954_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001428 284.0
PYH2_k127_196954_2 PFAM Carboxymuconolactone decarboxylase - - - 0.000000000000000000000000000000000000002422 152.0
PYH2_k127_196954_3 OsmC-like protein - - - 0.000000000000000000000721 102.0
PYH2_k127_196954_4 response regulator receiver K02481,K07713 - - 0.00002914 51.0
PYH2_k127_1972653_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses K01916,K01950 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008795,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016874,GO:0016879,GO:0016880,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5,6.3.5.1 6.181e-212 674.0
PYH2_k127_1972653_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002982 246.0
PYH2_k127_1972653_2 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000002002 220.0
PYH2_k127_1984674_0 Tfp pilus assembly protein pilus retraction ATPase PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 338.0
PYH2_k127_1984674_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 297.0
PYH2_k127_1984674_2 DNA polymerase K02347 - - 0.00000000001978 67.0
PYH2_k127_1997676_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004798 474.0
PYH2_k127_1997676_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 297.0
PYH2_k127_1997676_2 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000001193 227.0
PYH2_k127_1997676_3 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000000000000158 203.0
PYH2_k127_1997676_4 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 - 2.7.1.156,2.7.7.62 0.0000000000000000000000000000000000002893 145.0
PYH2_k127_2045078_0 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 453.0
PYH2_k127_2045078_1 Bacterial regulatory proteins, crp family - - - 0.000000000000000000000000000000000000000000000000001523 190.0
PYH2_k127_2045078_2 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000008322 99.0
PYH2_k127_2051776_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.279e-195 630.0
PYH2_k127_2051776_1 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 384.0
PYH2_k127_2051776_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000001653 150.0
PYH2_k127_2072491_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 2.139e-303 945.0
PYH2_k127_2072491_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005275 266.0
PYH2_k127_2072491_2 heat shock protein binding - - - 0.000000000000000000000000000000000003625 148.0
PYH2_k127_2072491_3 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000003053 125.0
PYH2_k127_2190240_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.997e-249 780.0
PYH2_k127_2190240_1 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 374.0
PYH2_k127_2190240_2 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009167 297.0
PYH2_k127_2190240_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000005602 254.0
PYH2_k127_2190240_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000005975 213.0
PYH2_k127_2190240_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000001122 214.0
PYH2_k127_2244589_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 2.264e-284 897.0
PYH2_k127_2244589_1 Glycosyl hydrolase family 57 - - - 1.304e-220 706.0
PYH2_k127_2244589_10 cell cycle K05589,K12065,K13052 - - 0.000000000000001907 80.0
PYH2_k127_2244589_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 460.0
PYH2_k127_2244589_3 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 410.0
PYH2_k127_2244589_4 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 376.0
PYH2_k127_2244589_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 321.0
PYH2_k127_2244589_6 CHASE K02488,K21009 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000001492 229.0
PYH2_k127_2244589_7 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0040007,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000001338 174.0
PYH2_k127_2244589_8 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000004291 169.0
PYH2_k127_2244589_9 - - - - 0.000000000000000000000000000003861 135.0
PYH2_k127_2250932_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 5.085e-200 629.0
PYH2_k127_2250932_1 DNA recombination-mediator protein A K03168,K04096 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002503 338.0
PYH2_k127_2250932_2 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 314.0
PYH2_k127_2250932_3 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000001723 111.0
PYH2_k127_2252353_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 296.0
PYH2_k127_2252353_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 GO:0003674,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0040007,GO:0042802,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000001659 74.0
PYH2_k127_2252353_4 HEAT repeats - - - 0.0000000001055 65.0
PYH2_k127_2285552_0 MlaA lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000001434 225.0
PYH2_k127_2285552_1 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.000000000000000000000000000000008282 129.0
PYH2_k127_2285552_2 - - - - 0.000000000000000000001893 102.0
PYH2_k127_232737_0 Anthranilate synthase component I, N terminal region K01657,K13503 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 565.0
PYH2_k127_232737_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 465.0
PYH2_k127_232737_10 PFAM DsrE K07235 - - 0.00007388 50.0
PYH2_k127_232737_11 Belongs to the DsrF TusC family K07236 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.0001259 48.0
PYH2_k127_232737_12 - - - - 0.0003852 45.0
PYH2_k127_232737_2 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 366.0
PYH2_k127_232737_3 TIGRFAM glutamine amidotransferase of anthranilate synthase K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 312.0
PYH2_k127_232737_4 zinc ion binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001874 254.0
PYH2_k127_232737_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000004072 196.0
PYH2_k127_232737_6 Transcriptional regulator - - - 0.00000000000000000000002284 102.0
PYH2_k127_232737_7 DNA-binding transcription factor activity K03655,K03892,K21903 - 3.6.4.12 0.0000000000000000000005336 100.0
PYH2_k127_232737_8 Tetratricopeptide repeat-like domain - - - 0.000000000000709 78.0
PYH2_k127_232737_9 Belongs to the SAICAR synthetase family K01923,K01945 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6,6.3.4.13 0.00000003474 55.0
PYH2_k127_2336423_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 506.0
PYH2_k127_2336423_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000001396 225.0
PYH2_k127_2336423_2 glycolate biosynthetic process K01091 - 3.1.3.18 0.000000000000000000000000000000000001571 141.0
PYH2_k127_2336423_3 - - - - 0.00000000000000000000003275 102.0
PYH2_k127_235345_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1381.0
PYH2_k127_235345_1 PFAM Polysulphide reductase, NrfD K00185 - - 9.279e-222 700.0
PYH2_k127_235345_10 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.0000000000000000000007383 104.0
PYH2_k127_235345_11 Cytochrome C oxidase subunit II, periplasmic domain K02275 - 1.9.3.1 0.000006032 54.0
PYH2_k127_235345_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004358 535.0
PYH2_k127_235345_3 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 404.0
PYH2_k127_235345_4 Proto-chlorophyllide reductase 57 kD subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 348.0
PYH2_k127_235345_5 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000001085 246.0
PYH2_k127_235345_6 Proto-chlorophyllide reductase 57 kD subunit - - - 0.000000000000000000000000000000000000000000000000000002542 204.0
PYH2_k127_235345_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000394 146.0
PYH2_k127_235345_8 helix_turn_helix, cAMP Regulatory protein K10914,K21563 - - 0.000000000000000000000000000003058 129.0
PYH2_k127_235345_9 protein complex oligomerization - - - 0.0000000000000000000002155 106.0
PYH2_k127_2371838_0 Probable molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 317.0
PYH2_k127_2371838_1 FmdE, Molybdenum formylmethanofuran dehydrogenase operon K11261 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000002569 247.0
PYH2_k127_2371838_2 Catalyzes the reduction of arsenate As(V) to arsenite As(III) K03741 - 1.20.4.1 0.000000000000000000000000000000000000000002158 158.0
PYH2_k127_2371838_3 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000007709 128.0
PYH2_k127_2377673_0 PFAM sigma-54 factor interaction domain-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 299.0
PYH2_k127_2377673_1 COGs COG4191 Signal transduction histidine kinase regulating C4-dicarboxylate transport system - - - 0.0000000000000000000000000000000000000000000000000005249 208.0
PYH2_k127_2412372_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 411.0
PYH2_k127_2412372_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 321.0
PYH2_k127_245398_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1105.0
PYH2_k127_245398_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004636 434.0
PYH2_k127_245398_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 424.0
PYH2_k127_245398_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 382.0
PYH2_k127_245398_4 Domain of unknown function (DUF4416) - - - 0.0000000000000000000000000000000000000000000001552 173.0
PYH2_k127_245398_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000002521 140.0
PYH2_k127_2459060_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 1.31e-312 969.0
PYH2_k127_2459060_1 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 380.0
PYH2_k127_2459060_2 Stringent starvation protein B K09985 - - 0.000000000000000000000000002056 118.0
PYH2_k127_2459060_3 SMART Cold shock protein K03704 - - 0.000000001053 61.0
PYH2_k127_2491808_0 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 352.0
PYH2_k127_2491808_1 DeoC/LacD family aldolase K08321 - 2.3.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005474 334.0
PYH2_k127_2491808_2 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000004153 63.0
PYH2_k127_2496454_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 1.238e-258 807.0
PYH2_k127_2496454_1 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000985 180.0
PYH2_k127_2496454_2 Belongs to the small heat shock protein (HSP20) family K06335,K13993 GO:0001666,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006457,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007154,GO:0008150,GO:0008152,GO:0009266,GO:0009267,GO:0009408,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0009991,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016310,GO:0019538,GO:0030312,GO:0031667,GO:0031668,GO:0031669,GO:0033554,GO:0036211,GO:0036293,GO:0036294,GO:0040007,GO:0040008,GO:0042221,GO:0042594,GO:0043170,GO:0043207,GO:0043412,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044121,GO:0044183,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045926,GO:0046777,GO:0048519,GO:0050789,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0065007,GO:0070482,GO:0070887,GO:0071453,GO:0071456,GO:0071496,GO:0071704,GO:0071944,GO:0075136,GO:1901564 - 0.00000000000000000000000000000000000000001505 158.0
PYH2_k127_254630_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 394.0
PYH2_k127_254630_1 SagB-type dehydrogenase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 327.0
PYH2_k127_254630_2 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000004608 197.0
PYH2_k127_256686_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 418.0
PYH2_k127_256686_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 349.0
PYH2_k127_256686_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000008769 175.0
PYH2_k127_256686_3 SurA N-terminal domain K03771 - 5.2.1.8 0.0000000000000000000000000000003894 135.0
PYH2_k127_256686_4 peptidyl-tyrosine sulfation - - - 0.00002937 50.0
PYH2_k127_256884_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0 1060.0
PYH2_k127_256884_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 6.794e-232 728.0
PYH2_k127_256884_2 molybdopterin oxidoreductase Fe4S4 region K05299 - 1.17.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 517.0
PYH2_k127_256884_3 N-Acyl-D-aspartate D-glutamate deacylase K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 377.0
PYH2_k127_256884_4 Family 5 K02035,K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004975 355.0
PYH2_k127_256884_5 translation release factor activity K03265 GO:0001666,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006950,GO:0008150,GO:0009628,GO:0016020,GO:0030312,GO:0036293,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0070482,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 329.0
PYH2_k127_256884_6 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 314.0
PYH2_k127_256884_7 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000002859 213.0
PYH2_k127_256884_8 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000131 167.0
PYH2_k127_2572732_0 NfeD-like C-terminal, partner-binding K07403 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 483.0
PYH2_k127_2572732_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 373.0
PYH2_k127_2572732_2 PFAM SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004234 263.0
PYH2_k127_2572732_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000004093 191.0
PYH2_k127_2572732_4 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000001052 125.0
PYH2_k127_2572732_5 cheY-homologous receiver domain - - - 0.0000003721 61.0
PYH2_k127_2602118_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase K03182,K16239,K16874 - 4.1.1.61,4.1.1.98 7.341e-199 628.0
PYH2_k127_2602118_1 Response regulator, receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 501.0
PYH2_k127_2602118_2 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003904 257.0
PYH2_k127_2602118_3 Protein of unknown function, DUF480 K09915 - - 0.0000000000000000000000000000000000000000000000000000000002206 210.0
PYH2_k127_2602118_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000007866 164.0
PYH2_k127_2602118_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000003135 148.0
PYH2_k127_2602118_6 - - - - 0.00000000000000000192 90.0
PYH2_k127_263468_0 Conserved region in glutamate synthase - - - 1.694e-274 850.0
PYH2_k127_263468_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000008774 239.0
PYH2_k127_2642775_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 3.966e-274 859.0
PYH2_k127_2642775_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274,K02298 - 1.10.3.10,1.9.3.1 3.617e-235 737.0
PYH2_k127_2642775_2 ferrous iron transmembrane transporter activity K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 350.0
PYH2_k127_2642775_3 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000002358 235.0
PYH2_k127_2642775_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000003081 114.0
PYH2_k127_2642775_5 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.000000000000000000000000005383 114.0
PYH2_k127_2642775_6 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000007473 112.0
PYH2_k127_2649099_0 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 434.0
PYH2_k127_2649099_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 401.0
PYH2_k127_2649099_2 Protein of unknown function (DUF520) K09767 - - 0.0000000000000000000000000000000000000000000000000000000000001526 217.0
PYH2_k127_2649099_3 Zinc dependent phospholipase C - - - 0.00000000000000000000000000000000000000000000000001564 189.0
PYH2_k127_2649099_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000138 76.0
PYH2_k127_2708237_0 5-formyltetrahydrofolate cyclo-ligase activity K07137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 602.0
PYH2_k127_2708237_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 324.0
PYH2_k127_2708237_2 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000009906 234.0
PYH2_k127_2708237_3 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000000000000002949 148.0
PYH2_k127_2708237_4 PFAM Rubredoxin-type Fe(Cys)4 protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000001288 104.0
PYH2_k127_2708237_5 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000003246 85.0
PYH2_k127_2709123_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000009163 238.0
PYH2_k127_2709123_1 SMART HNH nuclease K07451 - - 0.00000000000000000000000000000000000001051 148.0
PYH2_k127_2709123_2 - - - - 0.00001303 50.0
PYH2_k127_2757629_0 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 511.0
PYH2_k127_2757629_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 436.0
PYH2_k127_2757629_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 418.0
PYH2_k127_2757629_3 DEAD DEAH box helicase domain protein K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002744 278.0
PYH2_k127_2757629_4 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000004633 137.0
PYH2_k127_278663_0 Surface antigen K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 616.0
PYH2_k127_278663_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007299 391.0
PYH2_k127_278663_10 - - - - 0.000000000000000002841 95.0
PYH2_k127_278663_11 protein secretion K09800 - - 0.000000001665 59.0
PYH2_k127_278663_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 346.0
PYH2_k127_278663_3 Belongs to the acetyltransferase family. ArgA subfamily K00619,K14681 GO:0003674,GO:0003824,GO:0004042,GO:0005488,GO:0005515,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016043,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0040007,GO:0042450,GO:0042802,GO:0042803,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046983,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000007632 228.0
PYH2_k127_278663_4 Two component, sigma54 specific, transcriptional regulator, Fis family K02667,K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000001474 213.0
PYH2_k127_278663_5 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000005861 210.0
PYH2_k127_278663_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000002114 215.0
PYH2_k127_278663_7 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.000000000000000000000000000000000000001905 154.0
PYH2_k127_278663_8 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000000000000000000000001248 132.0
PYH2_k127_2802284_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 596.0
PYH2_k127_2802284_1 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 571.0
PYH2_k127_2802284_10 - - - - 0.0000000000000000000000000000000000000005017 155.0
PYH2_k127_2802284_11 Glutaredoxin K03676 - - 0.0000000000004431 70.0
PYH2_k127_2802284_2 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 479.0
PYH2_k127_2802284_3 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005466 314.0
PYH2_k127_2802284_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006337 273.0
PYH2_k127_2802284_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000001102 257.0
PYH2_k127_2802284_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003497 252.0
PYH2_k127_2802284_7 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000000000000000009739 168.0
PYH2_k127_2802284_8 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000003144 153.0
PYH2_k127_2802284_9 Domain of unknown function (DUF3786) - - - 0.0000000000000000000000000000000000000000652 158.0
PYH2_k127_2810190_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 7.496e-284 880.0
PYH2_k127_2810190_1 Nucleotidyl transferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 378.0
PYH2_k127_2810190_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000006318 90.0
PYH2_k127_2810190_3 - - - - 0.00000000000000008143 91.0
PYH2_k127_28459_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 315.0
PYH2_k127_288994_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1068.0
PYH2_k127_288994_1 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 321.0
PYH2_k127_288994_2 metalloendopeptidase activity K03799 - - 0.000000000000000000000000000000000000000000000000000002127 210.0
PYH2_k127_2891170_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 613.0
PYH2_k127_2891170_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 427.0
PYH2_k127_2891170_10 PFAM secretion protein HlyD K01993 - - 0.0004391 44.0
PYH2_k127_2891170_2 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 384.0
PYH2_k127_2891170_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008959 299.0
PYH2_k127_2891170_4 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002177 302.0
PYH2_k127_2891170_5 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000897 276.0
PYH2_k127_2891170_6 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000003518 245.0
PYH2_k127_2891170_7 lyase activity - - - 0.00000000000000000000000000000000000000000000000000000003133 221.0
PYH2_k127_2891170_8 Transposase - - - 0.0000000000003729 76.0
PYH2_k127_2891170_9 PFAM transposase, IS4 family protein - - - 0.0000000438 57.0
PYH2_k127_2902225_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1076.0
PYH2_k127_2902225_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006159 541.0
PYH2_k127_2902225_10 Regulatory protein, FmdB family - - - 0.000003068 51.0
PYH2_k127_2902225_11 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0002845 52.0
PYH2_k127_2902225_12 - - - - 0.0005006 48.0
PYH2_k127_2902225_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 425.0
PYH2_k127_2902225_3 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005206 353.0
PYH2_k127_2902225_4 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003212 334.0
PYH2_k127_2902225_5 Belongs to the NadC ModD family K00767 GO:0003674,GO:0003824,GO:0004514,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016054,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034213,GO:0034641,GO:0034654,GO:0042737,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044424,GO:0044464,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0072526,GO:0090407,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005297 293.0
PYH2_k127_2902225_6 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000000000007952 234.0
PYH2_k127_2902225_7 COGs COG0655 Multimeric flavodoxin WrbA - - - 0.00000000000000000000000000000000000000000000209 170.0
PYH2_k127_2902225_9 response regulator - - - 0.00000000000000000000000000000002309 138.0
PYH2_k127_2940521_0 4Fe-4S dicluster domain - - - 7.437e-292 902.0
PYH2_k127_2940521_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 551.0
PYH2_k127_2940521_2 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 451.0
PYH2_k127_2940521_3 4 iron, 4 sulfur cluster binding K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005545 362.0
PYH2_k127_2940521_4 - - - - 0.0000000000000000000000000000000000000000000000000001858 188.0
PYH2_k127_2940521_5 4Fe-4S binding domain - - - 0.0000000000000256 74.0
PYH2_k127_2940521_6 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000007223 59.0
PYH2_k127_2940521_7 DsrE/DsrF-like family K07236 - - 0.00007601 50.0
PYH2_k127_2940521_8 DsrE/DsrF-like family K06039 - - 0.0001483 48.0
PYH2_k127_2948489_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 2.55e-261 813.0
PYH2_k127_2948489_1 metal cluster binding K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 317.0
PYH2_k127_2948489_2 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 304.0
PYH2_k127_2948489_3 ferredoxin-thioredoxin reductase activity - - - 0.0000000000000000000000000000000000000004649 151.0
PYH2_k127_2948489_4 phosphorelay signal transduction system - - - 0.000000000000000000000000000001129 139.0
PYH2_k127_2948489_5 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.0000000000000000000001468 102.0
PYH2_k127_2948489_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676,K06191,K07390,K21636 - 1.1.98.6 0.0000000000000000000003614 98.0
PYH2_k127_2948489_9 protein histidine kinase activity K01768,K03406,K07636,K07716,K17763 - 2.7.13.3,4.6.1.1 0.000000488 63.0
PYH2_k127_3080893_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 298.0
PYH2_k127_3080893_1 AAA domain K02450 - - 0.0000000000000000000000000000000000000000285 160.0
PYH2_k127_3080893_2 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000002685 151.0
PYH2_k127_3080893_3 peptidyl-tyrosine sulfation - - - 0.000008556 57.0
PYH2_k127_319695_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 298.0
PYH2_k127_319695_1 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000004524 245.0
PYH2_k127_319695_2 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000004338 231.0
PYH2_k127_319695_4 ATPase BadF BadG BcrA BcrD type - - - 0.0000000000002911 72.0
PYH2_k127_319695_5 Hypothetical methyltransferase K07755 - 2.1.1.137 0.000000000005037 67.0
PYH2_k127_3199637_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 2.64e-255 805.0
PYH2_k127_3199637_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 7.498e-226 714.0
PYH2_k127_3199637_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 447.0
PYH2_k127_3199637_3 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 384.0
PYH2_k127_3199637_4 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001054 238.0
PYH2_k127_3199637_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000005611 107.0
PYH2_k127_3199637_6 Nitrogen regulation - - - 0.00001587 49.0
PYH2_k127_3287157_0 Transcriptional regulator K11921,K19338 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008485 388.0
PYH2_k127_3287157_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004079 388.0
PYH2_k127_3287157_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000887 281.0
PYH2_k127_3287157_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002603 281.0
PYH2_k127_3287157_4 Predicted permease YjgP/YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001895 254.0
PYH2_k127_3287157_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000005069 201.0
PYH2_k127_3287157_6 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000000000000006948 161.0
PYH2_k127_3287157_7 permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000003213 140.0
PYH2_k127_3298774_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 378.0
PYH2_k127_3298774_1 - - - - 0.000007517 48.0
PYH2_k127_3348146_0 Aminotransferase class I and II K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 364.0
PYH2_k127_3348146_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000004107 232.0
PYH2_k127_3348146_2 Chemotaxis phosphatase CheX - - - 0.0000000000000000000000000000000000000000000000000001929 196.0
PYH2_k127_3348146_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000004598 159.0
PYH2_k127_3348146_4 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000001051 147.0
PYH2_k127_3395881_0 Sugar (and other) transporter K03446 - - 7.415e-233 729.0
PYH2_k127_3395881_1 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 496.0
PYH2_k127_3395881_2 HlyD membrane-fusion protein of T1SS K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000204 385.0
PYH2_k127_3395881_3 Belongs to the pirin family K06911 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 368.0
PYH2_k127_3395881_5 Outer membrane efflux protein - - - 0.000004127 48.0
PYH2_k127_343407_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002756 518.0
PYH2_k127_343407_1 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000000000000000000000000000000000000000001312 197.0
PYH2_k127_343407_2 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000002437 108.0
PYH2_k127_3446127_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 503.0
PYH2_k127_3446127_1 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006832 476.0
PYH2_k127_3446127_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000953 359.0
PYH2_k127_3446127_3 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000005949 143.0
PYH2_k127_3446127_5 Participates in both transcription termination and antitermination K02600 - - 0.000002515 51.0
PYH2_k127_3469558_0 ATP-dependent Clp protease ATP-binding subunit ClpA K03694 - - 2.259e-242 760.0
PYH2_k127_3469558_1 leucyltransferase activity K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0044424,GO:0044464,GO:0140096 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 289.0
PYH2_k127_3469558_2 heat shock protein binding K05516,K05801 - - 0.00001734 49.0
PYH2_k127_3524050_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 514.0
PYH2_k127_3524050_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 389.0
PYH2_k127_3524050_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000009995 250.0
PYH2_k127_3524050_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00005963 48.0
PYH2_k127_3547825_0 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000000003581 171.0
PYH2_k127_3547825_1 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000008604 116.0
PYH2_k127_3547825_2 Protein of unknown function (DUF507) - - - 0.00000000000000000000000003399 110.0
PYH2_k127_3547825_3 Protein of unknown function (DUF507) - - - 0.000000000000000000000007341 103.0
PYH2_k127_3547825_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000004543 100.0
PYH2_k127_3547825_5 phosphorelay signal transduction system K20919 - - 0.000000000000000017 84.0
PYH2_k127_362475_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 503.0
PYH2_k127_362475_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 467.0
PYH2_k127_3630775_0 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0098655,GO:0098656,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 329.0
PYH2_k127_3630775_1 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005747 271.0
PYH2_k127_3630775_2 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005619 267.0
PYH2_k127_3630775_3 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000001793 207.0
PYH2_k127_3630775_4 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.00000000000000000000000000000000000000000000000000003831 190.0
PYH2_k127_3630775_5 Acylphosphatase K01512 - 3.6.1.7 0.000000000000000000000000005329 112.0
PYH2_k127_3630775_6 - - - - 0.0000000000000000001509 98.0
PYH2_k127_365434_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 481.0
PYH2_k127_365434_1 Male sterility protein K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 338.0
PYH2_k127_365434_2 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.0000000000000000000001418 102.0
PYH2_k127_365434_3 Transcriptional regulators - - - 0.00000003341 56.0
PYH2_k127_3772569_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 598.0
PYH2_k127_3772569_1 Belongs to the citrate synthase family K01659 - 2.3.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 556.0
PYH2_k127_3772569_2 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0000000000000000000000000000000000000000000000001992 178.0
PYH2_k127_3772569_3 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000001505 167.0
PYH2_k127_37822_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 392.0
PYH2_k127_37822_1 C-terminal, D2-small domain, of ClpB protein K03694 - - 0.0000000000000000000000000000000000000000000000000000000000000002454 227.0
PYH2_k127_37822_2 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000004192 127.0
PYH2_k127_3784603_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 365.0
PYH2_k127_3784603_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 GO:0003674,GO:0003824,GO:0004333,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006106,GO:0006108,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0055114,GO:0071704,GO:0072350 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000982 257.0
PYH2_k127_3784603_2 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000000000000000209 106.0
PYH2_k127_3784603_3 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000004784 82.0
PYH2_k127_3784603_4 NusG domain II K00805 - 2.5.1.30 0.0000001102 58.0
PYH2_k127_3786389_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 540.0
PYH2_k127_3786389_1 Staphylococcal nuclease homologues - - - 0.000000000000000000000000007666 113.0
PYH2_k127_3786389_3 - - - - 0.0001261 53.0
PYH2_k127_3851960_0 CO dehydrogenase K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008879 287.0
PYH2_k127_3851960_1 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000002281 157.0
PYH2_k127_3851960_2 regulator, PATAN and FRGAF domain-containing - - - 0.0000000000000008044 83.0
PYH2_k127_3853881_0 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000000000000001259 212.0
PYH2_k127_3853881_1 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000006127 164.0
PYH2_k127_3853881_2 Histidine kinase - - - 0.0000000000000000000000000000000001142 148.0
PYH2_k127_3874919_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 338.0
PYH2_k127_3874919_1 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 295.0
PYH2_k127_3874919_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000002922 247.0
PYH2_k127_3874919_3 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000000004338 206.0
PYH2_k127_3874919_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000623 93.0
PYH2_k127_3902311_0 Belongs to the peptidase S16 family K01338,K04076 - 3.4.21.53 0.0 1061.0
PYH2_k127_3902311_1 Domains REC, sigma54 interaction, HTH8 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 488.0
PYH2_k127_3902311_10 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000007749 173.0
PYH2_k127_3902311_11 PFAM CBS domain - - - 0.0000000000000000000000000000000003 138.0
PYH2_k127_3902311_12 PFAM aminoglycoside phosphotransferase K18817 - 2.7.1.163 0.0000000000000000000000000000000005085 144.0
PYH2_k127_3902311_13 RNase_H superfamily K07502 - - 0.00006371 46.0
PYH2_k127_3902311_2 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 436.0
PYH2_k127_3902311_3 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003309 424.0
PYH2_k127_3902311_4 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000289 417.0
PYH2_k127_3902311_5 Phage integrase, N-terminal SAM-like domain K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 324.0
PYH2_k127_3902311_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 286.0
PYH2_k127_3902311_7 AAA domain, putative AbiEii toxin, Type IV TA system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000000001627 246.0
PYH2_k127_3902311_8 PFAM HPP family K07168 - - 0.00000000000000000000000000000000000000000000000000000000000000006079 226.0
PYH2_k127_3902311_9 dTDP-4-dehydrorhamnose 3,5-epimerase activity K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000002556 185.0
PYH2_k127_3905376_0 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004327 281.0
PYH2_k127_3905376_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000002271 111.0
PYH2_k127_3919261_0 Heat shock 70 kDa protein K04043 - - 5e-324 1001.0
PYH2_k127_3919261_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006558 444.0
PYH2_k127_3919261_2 Uncharacterised conserved protein (DUF2156) K01163 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002285 273.0
PYH2_k127_3919261_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000004956 163.0
PYH2_k127_3919261_4 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000009296 100.0
PYH2_k127_3962229_0 Telomere recombination K04656 - - 3.881e-241 767.0
PYH2_k127_3962229_1 Hydrogenase formation hypA family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 446.0
PYH2_k127_3962229_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 424.0
PYH2_k127_3962229_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 316.0
PYH2_k127_3962229_4 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000008956 241.0
PYH2_k127_3962229_5 YtxH-like protein - - - 0.00000000000000000000000000000003844 129.0
PYH2_k127_3962229_7 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000000000006306 82.0
PYH2_k127_3962229_8 AIR synthase related protein, N-terminal domain K04655 - - 0.0000001155 56.0
PYH2_k127_3986908_0 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 346.0
PYH2_k127_3986908_1 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008372 325.0
PYH2_k127_3986908_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.00000000000000000000000000000000000000000000000000000000000003465 229.0
PYH2_k127_3986908_3 PFAM Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000000000000000000000006794 208.0
PYH2_k127_3986908_4 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000007425 211.0
PYH2_k127_3986908_5 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000003038 179.0
PYH2_k127_3986908_6 6-carboxyhexanoate--CoA ligase K01906 - 6.2.1.14 0.0000000000000000000000000000000000000000000000003079 185.0
PYH2_k127_3986908_7 carboxymuconolactone decarboxylase - - - 0.000000000000000000000000004414 114.0
PYH2_k127_3986908_8 Peptidase C26 K01951 - 6.3.5.2 0.000002304 49.0
PYH2_k127_3987698_0 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 3.08e-227 715.0
PYH2_k127_3987698_1 PFAM V-type ATPase 116 kDa K02123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 570.0
PYH2_k127_3987698_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000946 488.0
PYH2_k127_3987698_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000000000965 109.0
PYH2_k127_3987698_5 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000000009324 97.0
PYH2_k127_3987698_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000000000000004533 100.0
PYH2_k127_3987698_7 Histidine kinase - - - 0.0000000000000001856 83.0
PYH2_k127_4018647_0 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 541.0
PYH2_k127_4018647_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000001971 228.0
PYH2_k127_4018647_2 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000006683 218.0
PYH2_k127_4018647_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000004399 151.0
PYH2_k127_4018647_4 Belongs to the CarB family K01955 - 6.3.5.5 0.0000003625 52.0
PYH2_k127_4036764_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 8.591e-229 744.0
PYH2_k127_4036764_1 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 469.0
PYH2_k127_4036764_10 Glycosyltransferase like family 2 K12992 - - 0.0000000000003774 72.0
PYH2_k127_4036764_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 424.0
PYH2_k127_4036764_3 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008313 379.0
PYH2_k127_4036764_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003045 290.0
PYH2_k127_4036764_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000361 268.0
PYH2_k127_4036764_6 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000008182 225.0
PYH2_k127_4036764_7 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000006074 206.0
PYH2_k127_4036764_8 Belongs to the Nudix hydrolase family - - - 0.000000000000000000000000000000000006114 141.0
PYH2_k127_4036764_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000001897 142.0
PYH2_k127_4089769_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 2.032e-226 715.0
PYH2_k127_4089769_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003579 444.0
PYH2_k127_4089769_2 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 GO:0003674,GO:0003824,GO:0004749,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016772,GO:0016778,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000422 405.0
PYH2_k127_4089769_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000001396 236.0
PYH2_k127_4089769_4 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000003197 238.0
PYH2_k127_4089769_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.0000000000000000000000000000000000000000000000000000001946 199.0
PYH2_k127_4089769_6 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000004326 169.0
PYH2_k127_4104999_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.292e-310 977.0
PYH2_k127_4104999_1 7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase activity K11779,K11780,K11781,K11784,K18285 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016740,GO:0016765,GO:0044237,GO:0044249,GO:0044689,GO:0051186,GO:0051188 1.21.98.1,2.5.1.120,2.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 475.0
PYH2_k127_4104999_2 alcohol dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 322.0
PYH2_k127_4104999_3 - - - - 0.0000000000000000000000000000000000000000000000000003763 191.0
PYH2_k127_4189800_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 5e-324 1013.0
PYH2_k127_4189800_1 PFAM ABC transporter related K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006704 340.0
PYH2_k127_4189800_2 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000276 211.0
PYH2_k127_4189800_3 Gram-negative-bacterium-type cell outer membrane assembly K04064,K06186 GO:0006950,GO:0006970,GO:0008150,GO:0009628,GO:0050896 - 0.00000000000000000000000000002343 121.0
PYH2_k127_4189800_4 cyclopropane-fatty-acyl-phospholipid synthase K00568 - 2.1.1.222,2.1.1.64 0.000122 53.0
PYH2_k127_4220258_0 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 308.0
PYH2_k127_4220258_1 Arginine-tRNA-protein transferase, N terminus K21420 - 2.3.2.29 0.0000000000000000000000000000000000005102 149.0
PYH2_k127_4231246_0 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 318.0
PYH2_k127_4231246_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002097 307.0
PYH2_k127_4231833_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 461.0
PYH2_k127_4231833_1 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 320.0
PYH2_k127_4231833_2 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000001013 231.0
PYH2_k127_4245613_0 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 313.0
PYH2_k127_4245613_1 Transglycosylase SLT domain - - - 0.0000000007514 67.0
PYH2_k127_426511_0 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 355.0
PYH2_k127_426511_2 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.00000000000006612 76.0
PYH2_k127_426511_3 Cytochrome C oxidase subunit II, periplasmic domain protein K00376 - 1.7.2.4 0.00000006489 60.0
PYH2_k127_428282_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 394.0
PYH2_k127_428282_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 332.0
PYH2_k127_428282_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000001265 156.0
PYH2_k127_428282_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000001505 144.0
PYH2_k127_428282_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000009934 138.0
PYH2_k127_428282_13 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000000008232 111.0
PYH2_k127_428282_14 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007041 104.0
PYH2_k127_428282_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000008041 102.0
PYH2_k127_428282_16 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000006979 68.0
PYH2_k127_428282_17 Forms part of the polypeptide exit tunnel K02926 - - 0.0000007365 52.0
PYH2_k127_428282_2 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002775 267.0
PYH2_k127_428282_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000002527 239.0
PYH2_k127_428282_4 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000003298 233.0
PYH2_k127_428282_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000002323 215.0
PYH2_k127_428282_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000008944 199.0
PYH2_k127_428282_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000005904 163.0
PYH2_k127_428282_8 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000006161 160.0
PYH2_k127_428282_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000002022 156.0
PYH2_k127_4283955_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 449.0
PYH2_k127_4283955_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 326.0
PYH2_k127_4283955_2 Belongs to the MtfA family K09933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 315.0
PYH2_k127_4283955_3 DJ-1/PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000000000000000009921 248.0
PYH2_k127_4283955_4 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.000000000000000000000000000000000000000000005204 164.0
PYH2_k127_4283955_5 PFAM outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000007402 175.0
PYH2_k127_4308217_0 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 2.014e-228 723.0
PYH2_k127_4308217_1 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 586.0
PYH2_k127_4308217_2 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 370.0
PYH2_k127_4308217_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000008597 143.0
PYH2_k127_4308217_4 JAB/MPN domain K21140 - 3.13.1.6 0.00000000000000000000000000001285 122.0
PYH2_k127_4308217_5 Sulfurtransferase TusA K04085 - - 0.000000000000001822 79.0
PYH2_k127_4308217_6 Belongs to the peptidase M16 family K07263 - - 0.0000001733 57.0
PYH2_k127_4347449_0 Ftsk_gamma K03466 - - 3.897e-206 662.0
PYH2_k127_4347449_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 388.0
PYH2_k127_4347449_2 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000009653 160.0
PYH2_k127_4347449_3 DNA polymerase beta domain protein region K07075 - - 0.00000000000000000000000000000000003956 136.0
PYH2_k127_4347449_4 Protein of unknown function DUF86 - - - 0.0000000000000000000000000000001404 128.0
PYH2_k127_4347449_5 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.0002677 44.0
PYH2_k127_4365261_0 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 479.0
PYH2_k127_4365261_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 433.0
PYH2_k127_4365261_2 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 291.0
PYH2_k127_4365261_3 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00652 - 2.3.1.47 0.0000000000000000000000000000000000005923 144.0
PYH2_k127_439107_0 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000232 194.0
PYH2_k127_439107_1 Enoyl-(Acyl carrier protein) reductase K10780 - 1.3.1.104 0.000000000000000000000000000000000000000000004532 175.0
PYH2_k127_439107_2 3-oxoacyl-[acyl-carrier-protein] synthase activity K09458,K17255 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009117,GO:0009150,GO:0009259,GO:0009657,GO:0009668,GO:0009987,GO:0010027,GO:0016043,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046459,GO:0046483,GO:0051186,GO:0051790,GO:0051791,GO:0051792,GO:0055086,GO:0061024,GO:0071704,GO:0071840,GO:0072330,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901576 2.3.1.179 0.00000000000002162 78.0
PYH2_k127_439107_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K01666,K01897,K01909,K02078,K04791,K12424,K12436,K12439,K12442,K12443,K15320,K15673,K16030,K16128 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009273,GO:0009987,GO:0016874,GO:0042546,GO:0044085,GO:0044238,GO:0071554,GO:0071704,GO:0071766,GO:0071840,GO:1901576 2.3.1.165,4.1.3.39,6.2.1.20,6.2.1.3,6.2.1.50 0.000000000009607 72.0
PYH2_k127_4409089_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 7.433e-292 912.0
PYH2_k127_4409089_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000061 252.0
PYH2_k127_4413637_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1019.0
PYH2_k127_4413637_1 Penicillin-binding protein OB-like domain K05366 - 2.4.1.129,3.4.16.4 7.207e-251 797.0
PYH2_k127_4413637_2 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 509.0
PYH2_k127_4413637_3 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005558 363.0
PYH2_k127_4413637_4 Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000002928 205.0
PYH2_k127_4413637_5 Transcriptional regulator, MerR family - - - 0.00000000000000000000000000000000001509 140.0
PYH2_k127_4430963_0 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001473 349.0
PYH2_k127_4430963_1 Organic solvent tolerance protein K04744 - - 0.000007689 53.0
PYH2_k127_4431828_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 1.483e-216 689.0
PYH2_k127_4431828_1 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 425.0
PYH2_k127_4431828_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 300.0
PYH2_k127_4431828_3 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000001842 109.0
PYH2_k127_4431828_4 acetoacetate metabolism regulatory protein AtoC K07714 K02481 - - 0.00000000000000156 81.0
PYH2_k127_4434339_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1026.0
PYH2_k127_4434339_1 LysM domain K08307,K12204,K16291 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 332.0
PYH2_k127_4434339_2 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000001048 260.0
PYH2_k127_4434339_3 - - - - 0.0000000000000000000000000000000000000001375 153.0
PYH2_k127_4434339_5 HEAT repeat - - - 0.000001669 58.0
PYH2_k127_4434339_6 protein conserved in bacteria K00805 - 2.5.1.30 0.000001689 53.0
PYH2_k127_4574651_0 Penicillin-binding Protein dimerisation domain K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009605 604.0
PYH2_k127_4574651_1 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 550.0
PYH2_k127_4574651_2 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008239 489.0
PYH2_k127_4574651_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 400.0
PYH2_k127_4574651_4 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000002489 130.0
PYH2_k127_4574651_5 RDD family - - - 0.00000000000000000000000001119 115.0
PYH2_k127_4574651_6 rod shape-determining protein MreD K03571 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0008360,GO:0016020,GO:0016021,GO:0022603,GO:0022604,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0065007,GO:0065008,GO:0071944 - 0.0002093 49.0
PYH2_k127_4576418_0 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 509.0
PYH2_k127_4576418_1 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 382.0
PYH2_k127_4576418_2 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 287.0
PYH2_k127_4576418_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000006339 106.0
PYH2_k127_4576418_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000006814 60.0
PYH2_k127_4617459_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 2.346e-248 775.0
PYH2_k127_4617459_1 FMN binding - - - 0.000000000000000000000000000000000000000000000000000000000000004366 221.0
PYH2_k127_4617459_2 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000005574 119.0
PYH2_k127_4634929_0 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 561.0
PYH2_k127_4634929_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001598 271.0
PYH2_k127_4634929_2 PFAM Glycosyl transferase family 2 - - - 0.000000000001637 68.0
PYH2_k127_4637077_0 Beta-lactamase - - - 6.496e-260 824.0
PYH2_k127_4637077_1 Putative glycosyl hydrolase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 495.0
PYH2_k127_4637077_2 DNA polymerase A domain K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 353.0
PYH2_k127_4637077_3 PFAM Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 335.0
PYH2_k127_4637077_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 314.0
PYH2_k127_4637077_5 MOSC domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000005887 204.0
PYH2_k127_4773318_0 SMART Elongator protein 3 MiaB NifB - - - 1.357e-206 653.0
PYH2_k127_4773318_1 Protoporphyrinogen oxidase - - - 0.00000000000000000000000000000000000000000006424 168.0
PYH2_k127_4773318_2 Iron-sulfur cluster-binding domain - - - 0.000000000000002971 76.0
PYH2_k127_4795279_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1202.0
PYH2_k127_4795279_1 Belongs to the GPI family K01810 - 5.3.1.9 2.756e-287 889.0
PYH2_k127_4795279_2 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 616.0
PYH2_k127_4795279_3 2,3-bisphosphoglycerate-independent phosphoglycerate mutase activity K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 296.0
PYH2_k127_4795279_4 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000003985 241.0
PYH2_k127_4814013_0 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007244 564.0
PYH2_k127_4814013_1 Mur ligase family, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004891 316.0
PYH2_k127_4814013_2 ABC-type polar amino acid transport system ATPase component K09972 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 295.0
PYH2_k127_4814013_3 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000002299 198.0
PYH2_k127_4832139_0 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000002221 184.0
PYH2_k127_4832139_1 sulfur carrier activity - GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000005257 60.0
PYH2_k127_4832139_2 Ferritin-like domain K03594 - 1.16.3.1 0.000000007438 57.0
PYH2_k127_4832139_3 PFAM DsrE K07235 - - 0.0000002927 57.0
PYH2_k127_4832139_4 acetyltransferases and hydrolases with the alpha beta hydrolase fold K01046 - 3.1.1.3 0.000009296 57.0
PYH2_k127_4832139_5 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions K07237 GO:0002097,GO:0002098,GO:0002143,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1902494,GO:1990228,GO:1990234 - 0.00001405 51.0
PYH2_k127_4832139_6 Belongs to the DsrF TusC family K07236 - - 0.0003573 48.0
PYH2_k127_484371_0 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 348.0
PYH2_k127_484371_1 PFAM Class I peptide chain release factor - - - 0.00000000000000000000000000000000000000001729 155.0
PYH2_k127_484371_2 binding domain protein K07138 - - 0.00000000000002182 76.0
PYH2_k127_484371_3 Rubrerythrin - - - 0.000000000003185 73.0
PYH2_k127_4865393_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 2.113e-210 662.0
PYH2_k127_4865393_1 MacB-like periplasmic core domain K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 409.0
PYH2_k127_4871398_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 360.0
PYH2_k127_4871398_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 352.0
PYH2_k127_4871398_10 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000008352 154.0
PYH2_k127_4871398_11 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000000001661 152.0
PYH2_k127_4871398_12 PFAM Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000006218 141.0
PYH2_k127_4871398_13 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000004368 124.0
PYH2_k127_4871398_14 energy transducer activity K03646,K03832 - - 0.00000000000000000009109 98.0
PYH2_k127_4871398_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000003321 59.0
PYH2_k127_4871398_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 286.0
PYH2_k127_4871398_3 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002367 272.0
PYH2_k127_4871398_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000001294 247.0
PYH2_k127_4871398_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000005979 233.0
PYH2_k127_4871398_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000028 228.0
PYH2_k127_4871398_7 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000002491 215.0
PYH2_k127_4871398_8 MotA/TolQ/ExbB proton channel family K03562 - - 0.0000000000000000000000000000000000000000000000000000000002254 211.0
PYH2_k127_4871398_9 Outer membrane lipoprotein - - - 0.0000000000000000000000000000000000000000000000002724 187.0
PYH2_k127_4896168_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 569.0
PYH2_k127_4901453_0 Protein of unknown function (DUF1847) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 373.0
PYH2_k127_4901453_1 BAAT / Acyl-CoA thioester hydrolase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 347.0
PYH2_k127_4901453_2 cyclic diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000001264 170.0
PYH2_k127_4901453_3 COG NOG14600 non supervised orthologous group - - - 0.000000000000000006538 83.0
PYH2_k127_4901453_4 lyase activity - - - 0.000000000000004048 90.0
PYH2_k127_4913810_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 520.0
PYH2_k127_4913810_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 383.0
PYH2_k127_4913810_2 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002908 277.0
PYH2_k127_4913810_3 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000001117 264.0
PYH2_k127_4913810_4 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000001294 215.0
PYH2_k127_4914691_0 RNA-directed DNA polymerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 603.0
PYH2_k127_4914691_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000005887 231.0
PYH2_k127_4914691_2 - - - - 0.000000001723 62.0
PYH2_k127_4937346_0 NosL - - - 0.000000000000000000000000000000000000000000000004029 178.0
PYH2_k127_4937346_1 Thioredoxin-like - - - 0.00000000000000000000000000000003491 132.0
PYH2_k127_4937346_2 - - - - 0.000000000000000000006437 97.0
PYH2_k127_4974693_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 2.181e-220 696.0
PYH2_k127_4974693_1 Evidence 2b Function of strongly homologous gene - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 545.0
PYH2_k127_4974693_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006081 481.0
PYH2_k127_4975764_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 614.0
PYH2_k127_4975764_1 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 294.0
PYH2_k127_4975764_2 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001464 284.0
PYH2_k127_5015808_0 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 329.0
PYH2_k127_5015808_1 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 305.0
PYH2_k127_5015808_2 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 304.0
PYH2_k127_5015808_3 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000004297 239.0
PYH2_k127_5015808_4 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000003287 209.0
PYH2_k127_5015808_5 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000000000002896 163.0
PYH2_k127_5015808_6 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000006981 134.0
PYH2_k127_5015808_7 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000001957 97.0
PYH2_k127_5020491_0 Protein conserved in bacteria - - - 1.064e-231 745.0
PYH2_k127_5020491_1 chelatase, subunit ChlI K07391 - - 3.285e-210 664.0
PYH2_k127_5020491_10 Regulatory protein, FmdB family - - - 0.0000000000000000003889 88.0
PYH2_k127_5020491_11 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000005079 76.0
PYH2_k127_5020491_2 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003788 583.0
PYH2_k127_5020491_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 496.0
PYH2_k127_5020491_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 407.0
PYH2_k127_5020491_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008555 326.0
PYH2_k127_5020491_6 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003713 277.0
PYH2_k127_5020491_7 lactate metabolic process K11473,K18928 - - 0.00000000000000000000000000000000000000000000000000000000000000000196 242.0
PYH2_k127_5020491_8 PFAM PKD domain containing protein - - - 0.0000000000000000000000000001354 124.0
PYH2_k127_5118407_0 Cytochrome c554 and c-prime - - - 7.47e-251 807.0
PYH2_k127_5118407_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 469.0
PYH2_k127_5118407_10 Phospholipid methyltransferase - - - 0.00000000000000007577 89.0
PYH2_k127_5118407_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 411.0
PYH2_k127_5118407_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002654 276.0
PYH2_k127_5118407_4 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000002754 214.0
PYH2_k127_5118407_5 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000004504 208.0
PYH2_k127_5118407_6 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000001251 157.0
PYH2_k127_5118407_7 PFAM nitrogen-fixing NifU domain protein - - - 0.000000000000000000000001768 104.0
PYH2_k127_5118407_8 long-chain fatty acid transporting porin activity - - - 0.000000000000000000003131 105.0
PYH2_k127_5118407_9 META domain K03929 - - 0.00000000000000005492 96.0
PYH2_k127_5131720_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000111 258.0
PYH2_k127_5131720_1 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000008683 239.0
PYH2_k127_5131720_2 Belongs to the Fur family K03711,K09825 - - 0.000000000000000000000000000000000000000000000003797 175.0
PYH2_k127_5131720_3 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000000000000000001715 176.0
PYH2_k127_5131720_4 - - - - 0.0000000000000000000000000000000000000000001131 166.0
PYH2_k127_5131720_5 Belongs to the TPP enzyme family K00156,K00158 - 1.2.3.3,1.2.5.1 0.000000003555 64.0
PYH2_k127_5131720_6 Desulfoferrodoxin ferrous iron-binding K05919 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009055,GO:0009636,GO:0009987,GO:0010035,GO:0016491,GO:0016721,GO:0019430,GO:0022900,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.2 0.00000003128 55.0
PYH2_k127_518694_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1107.0
PYH2_k127_518694_1 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 466.0
PYH2_k127_518694_10 Iron-sulfur cluster-binding domain - - - 0.000003131 58.0
PYH2_k127_518694_11 Belongs to the 'phage' integrase family - - - 0.0001193 46.0
PYH2_k127_518694_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 394.0
PYH2_k127_518694_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 377.0
PYH2_k127_518694_4 4Fe-4S ferredoxin K00124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003251 268.0
PYH2_k127_518694_5 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000001834 207.0
PYH2_k127_518694_6 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000001883 147.0
PYH2_k127_518694_7 Protein involved in formate dehydrogenase formation K02380 - - 0.000000000000000000000000000000000007666 149.0
PYH2_k127_518694_8 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000000000435 144.0
PYH2_k127_518694_9 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000003387 113.0
PYH2_k127_5196373_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 2.636e-197 619.0
PYH2_k127_5196373_1 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000001483 160.0
PYH2_k127_5196373_2 COG COG0589 Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms - - - 0.0000000000000002788 89.0
PYH2_k127_5227198_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.159e-244 763.0
PYH2_k127_5227198_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.704e-233 730.0
PYH2_k127_5227198_2 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 366.0
PYH2_k127_5227198_3 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000001744 167.0
PYH2_k127_5257447_0 Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 359.0
PYH2_k127_5257447_1 PFAM Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000847 306.0
PYH2_k127_5257447_2 LemA family K03744 - - 0.00000000000000000001477 92.0
PYH2_k127_5301055_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 1.211e-195 619.0
PYH2_k127_5301055_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000003622 192.0
PYH2_k127_5301055_2 DNA-directed DNA polymerase activity K02340 - 2.7.7.7 0.0000000000000000000000001936 117.0
PYH2_k127_5301055_3 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000001419 88.0
PYH2_k127_5406727_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 621.0
PYH2_k127_5406727_1 Beta Propeller - - - 0.00000000000000000000000000000000000000000000000000000002311 202.0
PYH2_k127_5406727_2 gas vesicle protein - - - 0.00000000000000000005805 94.0
PYH2_k127_5406727_3 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000003174 87.0
PYH2_k127_543487_0 ABC transporter K09817 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003296 255.0
PYH2_k127_543487_1 ABC 3 transport family K09816,K09819 - - 0.00000000000000000000000000000000000000000000000000000000000006553 224.0
PYH2_k127_543487_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03387 - 1.8.1.9 0.00000000000000000000000000000000000000000000000003336 182.0
PYH2_k127_543487_3 PFAM periplasmic solute binding protein K09815 - - 0.000000000000000000000000000009913 122.0
PYH2_k127_5434998_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.242e-234 740.0
PYH2_k127_5434998_1 pfam psp1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005492 249.0
PYH2_k127_5434998_2 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.0000000000000000000000001156 115.0
PYH2_k127_5452531_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003755 263.0
PYH2_k127_5452531_1 DEAD DEAH box helicase K06877 - - 0.0000000000000000000000000000000000000000005136 160.0
PYH2_k127_5452531_2 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.000000000001025 69.0
PYH2_k127_5460414_0 response to heat K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003782 456.0
PYH2_k127_5460414_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000002513 183.0
PYH2_k127_5460414_2 - - - - 0.000000000000000000000000000000000000000000003764 167.0
PYH2_k127_5460414_3 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000004099 75.0
PYH2_k127_5460414_4 cheY-homologous receiver domain - - - 0.00000001488 56.0
PYH2_k127_5460414_5 Universal stress protein - - - 0.0000000813 59.0
PYH2_k127_5477461_0 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 366.0
PYH2_k127_5477461_1 - - - - 0.000000000000000000006658 105.0
PYH2_k127_5519373_0 Receptor family ligand binding region K01999 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006865,GO:0008150,GO:0015711,GO:0015803,GO:0015804,GO:0015818,GO:0015820,GO:0015829,GO:0015849,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0044464,GO:0046942,GO:0051179,GO:0051234,GO:0070728,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002716 391.0
PYH2_k127_5519373_1 Branched-chain amino acid transport system / permease component K01997 GO:0003333,GO:0003674,GO:0005215,GO:0005304,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006812,GO:0006820,GO:0006855,GO:0006865,GO:0008150,GO:0008324,GO:0008509,GO:0008514,GO:0015075,GO:0015171,GO:0015173,GO:0015175,GO:0015179,GO:0015188,GO:0015190,GO:0015192,GO:0015238,GO:0015318,GO:0015658,GO:0015711,GO:0015801,GO:0015803,GO:0015804,GO:0015807,GO:0015818,GO:0015820,GO:0015823,GO:0015829,GO:0015849,GO:0015893,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0042221,GO:0042493,GO:0043090,GO:0044425,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0089718,GO:0098655,GO:0098656,GO:0098657,GO:0098713,GO:0098739,GO:1902475,GO:1903714,GO:1903785,GO:1903825,GO:1905039 - 0.0000000000000000000000000000000000000000000000000000000000001607 216.0
PYH2_k127_5519373_2 COG0784 FOG CheY-like receiver - - - 0.000000000001022 76.0
PYH2_k127_5519373_3 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000002997 55.0
PYH2_k127_5519373_4 CHASE3 domain - - - 0.0000004685 54.0
PYH2_k127_5520759_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004422 551.0
PYH2_k127_5520759_1 ZIP Zinc transporter K07238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 395.0
PYH2_k127_5520759_2 Cytochrome c K08738 - - 0.000000000000000000000000000005751 123.0
PYH2_k127_5520759_3 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000003888 72.0
PYH2_k127_5520759_4 - - - - 0.0000000909 54.0
PYH2_k127_5520759_5 transferase activity, transferring glycosyl groups - - - 0.0000007522 57.0
PYH2_k127_5532382_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 299.0
PYH2_k127_5532382_1 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000003981 223.0
PYH2_k127_5532382_2 Preprotein translocase subunit K03210 - - 0.00000000000000000000000000000000000002465 146.0
PYH2_k127_55582_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000756 276.0
PYH2_k127_55582_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.0000000000000000876 83.0
PYH2_k127_55582_2 Domain of unknown function (DUF3786) - - - 0.0000000000004346 71.0
PYH2_k127_562424_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458,K14660 - 2.3.1.179 0.00000000000000000000000000000000001602 146.0
PYH2_k127_562424_1 Lipid A biosynthesis K02517 - 2.3.1.241 0.000000000000000000000000000000005078 141.0
PYH2_k127_563294_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009087 548.0
PYH2_k127_563294_1 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 472.0
PYH2_k127_563294_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009544 449.0
PYH2_k127_563294_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 411.0
PYH2_k127_563294_4 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 289.0
PYH2_k127_563294_5 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006206 256.0
PYH2_k127_563294_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000004903 226.0
PYH2_k127_563294_7 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000001917 211.0
PYH2_k127_5648033_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005154 263.0
PYH2_k127_5648033_1 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000000002472 75.0
PYH2_k127_5648033_2 Tetratricopeptide repeat - - - 0.000000000004691 75.0
PYH2_k127_5648033_3 - - - - 0.000000002519 67.0
PYH2_k127_5648986_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 6.297e-227 714.0
PYH2_k127_5648986_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008972 376.0
PYH2_k127_5648986_10 - - - - 0.0000000000000000000000001146 111.0
PYH2_k127_5648986_11 Uncharacterised protein family UPF0047 - - - 0.0000000007581 60.0
PYH2_k127_5648986_12 Regulatory protein, FmdB family - - - 0.0000004889 54.0
PYH2_k127_5648986_13 Recombinase zinc beta ribbon domain - - - 0.000000653 53.0
PYH2_k127_5648986_14 - - - - 0.0000009881 50.0
PYH2_k127_5648986_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 330.0
PYH2_k127_5648986_3 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001865 284.0
PYH2_k127_5648986_4 Formylmethanofuran dehydrogenase, subunit e K11261 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000001477 226.0
PYH2_k127_5648986_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002821 224.0
PYH2_k127_5648986_6 FeS cluster assembly scaffold protein NifU K04488 - - 0.00000000000000000000000000000000000000000000000000000000008604 205.0
PYH2_k127_5648986_7 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000000000004388 204.0
PYH2_k127_5648986_8 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000001576 181.0
PYH2_k127_5648986_9 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.00000000000000000000000000000000000003334 149.0
PYH2_k127_5662967_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 9.215e-276 863.0
PYH2_k127_5662967_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006297 530.0
PYH2_k127_5662967_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000001063 165.0
PYH2_k127_5662967_3 DNA topoisomerase type I activity K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000008043 160.0
PYH2_k127_5662967_4 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000001878 103.0
PYH2_k127_5676929_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 596.0
PYH2_k127_5676929_1 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 398.0
PYH2_k127_5676929_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 331.0
PYH2_k127_5676929_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002177 232.0
PYH2_k127_5676929_4 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000001096 231.0
PYH2_k127_5676929_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000004058 200.0
PYH2_k127_5688065_0 Pyridoxal-phosphate dependent enzyme K06001 - 4.2.1.20 3.33e-227 710.0
PYH2_k127_5688065_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 529.0
PYH2_k127_5688065_2 Belongs to the TrpC family K01609,K13498 - 4.1.1.48,5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000173 250.0
PYH2_k127_5688065_3 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000000000006257 240.0
PYH2_k127_5688065_4 Lipoate-protein ligase K03800 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 6.3.1.20 0.000000000000000000000000000000000000000000000000009483 189.0
PYH2_k127_5688065_5 MazG-like family - - - 0.00000000000000000000000000000005686 130.0
PYH2_k127_5688065_6 Predicted RNA-binding protein - - - 0.00000000000000002358 84.0
PYH2_k127_5688065_7 beta-lactamase domain protein - - - 0.000004927 49.0
PYH2_k127_5750205_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 497.0
PYH2_k127_5750205_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 348.0
PYH2_k127_5750205_2 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007385 342.0
PYH2_k127_5750205_3 - - - - 0.00000000000000000000000000000000000000000000000000001281 202.0
PYH2_k127_5750205_4 Protein of unknown function DUF86 - - - 0.0000000000000000000000000003484 117.0
PYH2_k127_5750205_5 PFAM DNA polymerase, beta domain protein region K07075 - - 0.000000000000000000000002148 106.0
PYH2_k127_5775478_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008042 336.0
PYH2_k127_5775478_1 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003886 256.0
PYH2_k127_5775478_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000004936 93.0
PYH2_k127_5801250_0 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000286 587.0
PYH2_k127_5801250_1 Dehydratase family K01687 - 4.2.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 452.0
PYH2_k127_5801250_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 457.0
PYH2_k127_5801250_3 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 428.0
PYH2_k127_5801250_4 HD domain K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 405.0
PYH2_k127_5801250_5 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 317.0
PYH2_k127_5801250_6 His Kinase A (phosphoacceptor) domain K10715 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000009154 267.0
PYH2_k127_5801250_7 GTP-binding GTPase Middle Region K03665 - - 0.000000000000000000000000000000000000000001518 159.0
PYH2_k127_5801250_8 COG0784 FOG CheY-like receiver K11443 - - 0.000000000000000000003039 98.0
PYH2_k127_5801250_9 Protein of unknown function (DUF465) K09794 - - 0.0000000000000000009006 88.0
PYH2_k127_5821025_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.716e-294 917.0
PYH2_k127_5821025_1 Fructose-bisphosphate aldolase class-II - - - 1.265e-195 619.0
PYH2_k127_5821025_10 twitching motility protein K02669 - - 0.00000001132 58.0
PYH2_k127_5821025_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 7.617e-195 614.0
PYH2_k127_5821025_3 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004993 571.0
PYH2_k127_5821025_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 292.0
PYH2_k127_5821025_5 ROK family K00845,K13967,K19979,K20433 - 2.7.1.188,2.7.1.2,2.7.1.214,2.7.1.60,5.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000168 258.0
PYH2_k127_5821025_6 - - - - 0.00000000000000000000000000000000000000000000000000001991 199.0
PYH2_k127_5821025_7 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000003882 188.0
PYH2_k127_5821025_8 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000506 183.0
PYH2_k127_5821025_9 - - - - 0.000000004699 59.0
PYH2_k127_585350_0 4Fe-4S binding domain - - - 0.000000000000000000000000000008294 131.0
PYH2_k127_585350_1 Domain of unknown function (DUF4390) - - - 0.000078 52.0
PYH2_k127_5858887_0 Carbamoyl-phosphate synthetase large chain oligomerisation K01955 - 6.3.5.5 9.133e-285 894.0
PYH2_k127_5858887_1 PFAM phosphofructokinase K00850 - 2.7.1.11 0.0000000000000002914 80.0
PYH2_k127_5871399_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 3.94e-253 794.0
PYH2_k127_5871399_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001361 286.0
PYH2_k127_5871399_2 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K01883,K02533,K08281,K15396 - 2.1.1.200,3.5.1.19,6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000001576 246.0
PYH2_k127_5871399_3 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000001914 232.0
PYH2_k127_5871399_4 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000003611 191.0
PYH2_k127_5871399_5 Cobalt transport protein K02008 - - 0.00000000000000000000000000007709 128.0
PYH2_k127_5871399_6 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.0000000000000000001281 93.0
PYH2_k127_5876209_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002838 478.0
PYH2_k127_5876209_1 - - - - 0.00000000000000006195 90.0
PYH2_k127_5892912_0 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 327.0
PYH2_k127_5902262_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275,K02297 - 1.10.3.10,1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 321.0
PYH2_k127_5902262_1 cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000004371 248.0
PYH2_k127_5902262_10 TIGRFAM caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000006527 69.0
PYH2_k127_5902262_2 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000000000001126 215.0
PYH2_k127_5902262_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 GO:0003674,GO:0003824,GO:0004311,GO:0004659,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008495,GO:0009058,GO:0009987,GO:0015980,GO:0016020,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044464,GO:0045333,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.141 0.0000000000000000000000000000000000000000000000000000155 199.0
PYH2_k127_5902262_4 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000001461 181.0
PYH2_k127_5902262_5 DoxX K15977 - - 0.0000000000000000000000000000000000000000000000003606 181.0
PYH2_k127_5902262_6 Peptidase family M23 - - - 0.00000000000000000000000000000000000004246 151.0
PYH2_k127_5902262_7 phosphohydrolase - - - 0.0000000000000000000003764 107.0
PYH2_k127_5902262_8 cheY-homologous receiver domain - - - 0.00000000000000000003905 95.0
PYH2_k127_5902262_9 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000001122 93.0
PYH2_k127_5916850_0 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 421.0
PYH2_k127_5916850_1 Protein of unknown function (DUF3300) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 374.0
PYH2_k127_5979046_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 516.0
PYH2_k127_5979046_1 PFAM 4Fe-4S K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 323.0
PYH2_k127_6000787_0 Bacterial protein of unknown function (DUF853) K06915 - - 2.977e-206 649.0
PYH2_k127_6000787_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.00000000000000000000005872 107.0
PYH2_k127_6006274_0 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009026 581.0
PYH2_k127_6006274_1 PFAM response regulator receiver K03413 - - 0.0000000000000000000000000000000000000001318 154.0
PYH2_k127_6006274_2 STAS domain - - - 0.00004319 48.0
PYH2_k127_60243_0 ATPase BadF BadG BcrA BcrD type - - - 0.0 1171.0
PYH2_k127_6081886_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 473.0
PYH2_k127_6081886_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.00000000000000000000000000000000000000000000001191 177.0
PYH2_k127_6081886_2 cellulase activity - - - 0.000000000000000000000000000000003051 137.0
PYH2_k127_6081886_3 CAAX protease self-immunity K07052 - - 0.00000002804 64.0
PYH2_k127_6081886_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0003116 44.0
PYH2_k127_6142619_0 AMP-binding enzyme C-terminal domain K05939 - 2.3.1.40,6.2.1.20 4.995e-214 675.0
PYH2_k127_6142619_1 CAAX prenyl protease N-terminal, five membrane helices - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006713 467.0
PYH2_k127_6142619_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 434.0
PYH2_k127_6142619_3 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000001743 203.0
PYH2_k127_6142619_4 HNH nucleases - - - 0.00000000000000000000000000000000000000001638 155.0
PYH2_k127_6270971_0 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004148 290.0
PYH2_k127_6270971_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000008637 258.0
PYH2_k127_6270971_2 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000002464 251.0
PYH2_k127_6270971_3 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0000000000000000004273 87.0
PYH2_k127_6278775_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003417 465.0
PYH2_k127_6278775_1 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 341.0
PYH2_k127_6278775_2 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000008235 218.0
PYH2_k127_6278775_3 C-terminal, D2-small domain, of ClpB protein K03667 - - 0.00000000000000000008001 89.0
PYH2_k127_6278775_4 - - - - 0.00007211 49.0
PYH2_k127_6339248_0 LysM domain K01449,K19223 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000002899 263.0
PYH2_k127_6339248_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000001395 185.0
PYH2_k127_6339248_2 HTH-like domain K07497 - - 0.00000000000000000000000000000000000000000003515 169.0
PYH2_k127_6339248_3 transposase activity K07483 - - 0.00000000000000000003794 93.0
PYH2_k127_6339248_5 phosphoserine phosphatase activity K07315 - 3.1.3.3 0.00001996 56.0
PYH2_k127_6354548_0 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 363.0
PYH2_k127_6354548_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 365.0
PYH2_k127_6354548_2 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000174 199.0
PYH2_k127_6354548_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000006991 196.0
PYH2_k127_6357766_0 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.368e-303 939.0
PYH2_k127_6357766_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 365.0
PYH2_k127_6357766_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 342.0
PYH2_k127_6357766_3 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000004101 173.0
PYH2_k127_6372380_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003205 605.0
PYH2_k127_6372380_1 PFAM glycosyl transferase, family 9 K02849 - - 0.00000000000000000000000000000000002705 147.0
PYH2_k127_6372380_2 aminoglycoside 3-N-acetyltransferase activity K00662 - 2.3.1.81 0.000000000000000000000000002253 124.0
PYH2_k127_6372380_3 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0003677 49.0
PYH2_k127_6381285_0 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000002611 241.0
PYH2_k127_6381285_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000001925 229.0
PYH2_k127_6382278_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.573e-249 776.0
PYH2_k127_6382278_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005623 319.0
PYH2_k127_6382278_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000005874 137.0
PYH2_k127_6382278_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000001538 80.0
PYH2_k127_6382278_4 ATP synthesis coupled proton transport K02109,K18682 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000001824 64.0
PYH2_k127_6386100_0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007592 349.0
PYH2_k127_6386100_1 (AIR) carboxylase K06898 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001499 255.0
PYH2_k127_6386100_2 HD domain K06950 - - 0.00000000000000000000000000000000000000000000000000000000000000007623 226.0
PYH2_k127_6395808_0 cytochrome C - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 386.0
PYH2_k127_6395808_1 - - - - 0.0000000000000000000000000000000000000000216 174.0
PYH2_k127_6395808_2 SMART chemotaxis sensory transducer K03406 - - 0.000000000001725 71.0
PYH2_k127_6433522_0 Glycosyltransferase like family 2 K07011 - - 0.00000000000000000000000000000000000000000008262 167.0
PYH2_k127_6433522_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000003441 113.0
PYH2_k127_6499423_0 glutamine synthetase K01915 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0044464,GO:0050001,GO:0071944 6.3.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 590.0
PYH2_k127_6499423_1 Ribonuclease R winged-helix domain K09720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 284.0
PYH2_k127_6499423_2 Radical SAM superfamily K04070 - 1.97.1.4 0.000000000000000000000000000000000000000001083 158.0
PYH2_k127_6499423_3 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000002185 154.0
PYH2_k127_6516931_0 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 516.0
PYH2_k127_6516931_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 406.0
PYH2_k127_6516931_2 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002087 278.0
PYH2_k127_6516931_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000001213 99.0
PYH2_k127_6518197_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 607.0
PYH2_k127_6518197_1 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 543.0
PYH2_k127_6518197_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 524.0
PYH2_k127_6518197_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 454.0
PYH2_k127_6518197_4 Uncharacterized protein containing a ferredoxin domain (DUF2148) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001322 279.0
PYH2_k127_6518197_5 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000000003075 226.0
PYH2_k127_6518197_6 Universal stress protein family K07090 - - 0.000000000000000000000000000000000000000000000000000007603 199.0
PYH2_k127_6518197_7 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000006673 136.0
PYH2_k127_6559916_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001039 606.0
PYH2_k127_6559916_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 274.0
PYH2_k127_6559916_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000929 197.0
PYH2_k127_6559916_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000005356 154.0
PYH2_k127_6559916_4 cell redox homeostasis K02199 - - 0.00000000000000000000000000000000003497 139.0
PYH2_k127_6559916_5 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000000000001192 128.0
PYH2_k127_6559916_6 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000003333 103.0
PYH2_k127_6583381_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 4.489e-197 621.0
PYH2_k127_6583381_1 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 436.0
PYH2_k127_6583381_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000001728 208.0
PYH2_k127_6588731_0 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 425.0
PYH2_k127_6588731_1 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000005404 195.0
PYH2_k127_6588731_2 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000001414 176.0
PYH2_k127_6588731_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000001609 166.0
PYH2_k127_6588731_4 PFAM DAHP synthetase I KDSA K01627 - 2.5.1.55 0.00000000000000000001075 93.0
PYH2_k127_6607462_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 4.859e-276 855.0
PYH2_k127_6607462_1 Cytochrome c K08906,K12263 - - 0.0000000000000006607 81.0
PYH2_k127_6614390_0 Elongation factor G, domain IV K02355 - - 8.003e-308 957.0
PYH2_k127_6618193_0 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 505.0
PYH2_k127_6618193_1 PFAM ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 300.0
PYH2_k127_6618193_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000004781 267.0
PYH2_k127_6618193_3 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000007422 236.0
PYH2_k127_6618193_4 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000000000002016 190.0
PYH2_k127_6618193_5 Protein of unknown function (DUF512) - - - 0.00000000000000000000000000000000000000003671 156.0
PYH2_k127_6618193_6 Lipocalin-like domain - - - 0.000000000000000000000000000005462 127.0
PYH2_k127_6618193_7 OstA-like protein K09774 - - 0.0000000000000000000000001984 113.0
PYH2_k127_6618193_9 Lipopolysaccharide-assembly, LptC-related - - - 0.0000352 53.0
PYH2_k127_6635790_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 9.6e-289 897.0
PYH2_k127_6635790_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 334.0
PYH2_k127_6635790_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 301.0
PYH2_k127_6635790_3 Sporulation and spore germination - - - 0.000000000000001626 83.0
PYH2_k127_6654944_0 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009031 428.0
PYH2_k127_6654944_1 Dehydrogenase E1 component K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004665 394.0
PYH2_k127_6654944_10 - - - - 0.000000000000002515 83.0
PYH2_k127_6654944_11 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000001028 62.0
PYH2_k127_6654944_2 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 389.0
PYH2_k127_6654944_3 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 310.0
PYH2_k127_6654944_4 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001661 259.0
PYH2_k127_6654944_5 cell division ATP-binding protein FtsE K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000402 232.0
PYH2_k127_6654944_6 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000002477 171.0
PYH2_k127_6654944_7 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.000000000000000000000000000000000000000000003984 174.0
PYH2_k127_6654944_8 PFAM Outer membrane protein, OmpA MotB, C-terminal - - - 0.0000000000000000000005696 104.0
PYH2_k127_6654944_9 Sulfurtransferase TusA - - - 0.0000000000000000000174 93.0
PYH2_k127_6655581_0 myo-inosose-2 dehydratase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 311.0
PYH2_k127_6655581_1 Putative regulatory protein - - - 0.00000000000000000000008889 100.0
PYH2_k127_6655581_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000022 94.0
PYH2_k127_6659490_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002253 597.0
PYH2_k127_6659490_1 Protein of unknown function (DUF2400) - - - 0.00000000000000000000000000000000000000000000000000000000000000001164 235.0
PYH2_k127_6659490_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000469 225.0
PYH2_k127_6659490_3 Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate K07106 - 4.2.1.126 0.0000000000000000000000005133 107.0
PYH2_k127_6691826_0 Biotin carboxylase C-terminal domain K01961 - 6.3.4.14,6.4.1.2 2.113e-209 659.0
PYH2_k127_6691826_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008405 385.0
PYH2_k127_6691826_10 Domain of unknown function (DUF370) K09777 - - 0.000000000000000000000000000001879 123.0
PYH2_k127_6691826_11 Roadblock/LC7 domain - - - 0.00000000000000000000008382 102.0
PYH2_k127_6691826_12 Tetratricopeptide repeat - - - 0.00000000000000000000182 106.0
PYH2_k127_6691826_13 PFAM Rhodanese domain protein - - - 0.000000000000007136 74.0
PYH2_k127_6691826_2 PFAM peptidase M24 K01262,K01271 - 3.4.11.9,3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002564 279.0
PYH2_k127_6691826_3 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000292 248.0
PYH2_k127_6691826_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000005468 219.0
PYH2_k127_6691826_5 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000001234 201.0
PYH2_k127_6691826_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000168 177.0
PYH2_k127_6691826_7 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000000000000000000000000000000000000000005759 174.0
PYH2_k127_6691826_8 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000009184 177.0
PYH2_k127_6691826_9 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000001959 136.0
PYH2_k127_6698108_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 7.054e-231 722.0
PYH2_k127_6698108_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 1.649e-204 646.0
PYH2_k127_6698108_2 inositol-3-phosphate synthase activity K01858 GO:0003674,GO:0003824,GO:0004512,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009405,GO:0009987,GO:0010125,GO:0010126,GO:0016137,GO:0016138,GO:0016853,GO:0016872,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044272,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 554.0
PYH2_k127_6698108_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000001136 194.0
PYH2_k127_6698108_4 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000000000000000003199 131.0
PYH2_k127_6698108_5 Transcriptional regulator K02529 - - 0.00000000000000001122 92.0
PYH2_k127_6698108_6 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000003577 60.0
PYH2_k127_672072_0 COG0058 Glucan phosphorylase - - - 7.179e-256 799.0
PYH2_k127_672072_1 Histidine kinase - - - 2.577e-205 674.0
PYH2_k127_672072_10 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000004429 145.0
PYH2_k127_672072_11 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000001196 130.0
PYH2_k127_672072_12 - - - - 0.0000000000000000000000007537 104.0
PYH2_k127_672072_13 DnaJ molecular chaperone homology domain K09529 GO:0003674,GO:0005488,GO:0005515,GO:0030544,GO:0031072 - 0.0007648 49.0
PYH2_k127_672072_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 1.571e-201 639.0
PYH2_k127_672072_3 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005659 563.0
PYH2_k127_672072_4 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 456.0
PYH2_k127_672072_5 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006347 335.0
PYH2_k127_672072_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0003871,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0032259,GO:0042084,GO:0042085,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050667,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000097 301.0
PYH2_k127_672072_7 HD domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004258 287.0
PYH2_k127_672072_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000108 201.0
PYH2_k127_672072_9 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000004096 191.0
PYH2_k127_6764046_0 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000005855 226.0
PYH2_k127_6764046_1 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000002811 198.0
PYH2_k127_6764046_2 Methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000013 149.0
PYH2_k127_6801167_0 7TM receptor with intracellular HD hydrolase K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000063 294.0
PYH2_k127_6801167_1 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002595 257.0
PYH2_k127_6801167_2 UvrD REP helicase K03657,K16898 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000001918 276.0
PYH2_k127_6801167_3 PFAM diacylglycerol kinase K00887,K00901 - 2.7.1.107,2.7.1.66 0.00000000000000000000000000000000000000000000000158 181.0
PYH2_k127_6801167_4 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K01489,K07042 - 3.5.4.5 0.00000000000000000000002165 106.0
PYH2_k127_6801167_5 PD-(D/E)XK nuclease superfamily - - - 0.000000006374 69.0
PYH2_k127_6850713_0 Glycosyltransferase like family 2 K12992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002843 274.0
PYH2_k127_6850713_1 sugar transferase K00996 - 2.7.8.6 0.000000000000000000000000000000000000000000000000000000000000000000000000001947 267.0
PYH2_k127_6850713_2 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000001766 177.0
PYH2_k127_6859310_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.524e-247 782.0
PYH2_k127_6859310_1 Mo-molybdopterin cofactor metabolic process K03753,K07588 - - 0.0000000000000000000000000000000000000001631 159.0
PYH2_k127_6862992_0 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 402.0
PYH2_k127_6862992_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006772 320.0
PYH2_k127_6862992_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000005106 86.0
PYH2_k127_6887570_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1077.0
PYH2_k127_6887570_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 578.0
PYH2_k127_6887570_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 488.0
PYH2_k127_6887570_3 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 419.0
PYH2_k127_6887570_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 416.0
PYH2_k127_6887570_5 pfam abc K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 371.0
PYH2_k127_6887570_6 TIGRFAM succinate dehydrogenase (or fumarate reductase) cytochrome b subunit, b558 family K00241 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003517 253.0
PYH2_k127_6887570_7 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000002754 170.0
PYH2_k127_6887570_8 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000213 53.0
PYH2_k127_6898342_0 PFAM AMP-dependent synthetase and ligase K01908 - 6.2.1.17 0.0 1115.0
PYH2_k127_6898342_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003993 312.0
PYH2_k127_6898342_2 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000595 225.0
PYH2_k127_6898342_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K06191 - - 0.000000000000000000797 90.0
PYH2_k127_6906479_0 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 2.586e-233 739.0
PYH2_k127_6906479_1 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 299.0
PYH2_k127_6906479_2 TIGRFAM iron-sulfur cluster binding protein - - - 0.00000000000000000000000000000000000000000000001967 179.0
PYH2_k127_6906479_3 Methionine synthase, cobalamin (vitamin B12)-binding module, cap - - - 0.00003723 46.0
PYH2_k127_6922950_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008976,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016776,GO:0017076,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 319.0
PYH2_k127_6922950_1 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000287 219.0
PYH2_k127_6922950_2 Protein similar to CwfJ C-terminus 1 K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000025 211.0
PYH2_k127_6922950_3 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000003158 154.0
PYH2_k127_6922950_5 PFAM Uncharacterised protein family UPF0079, ATPase K06925 - - 0.00000000000000000000000316 108.0
PYH2_k127_6922950_6 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000001897 97.0
PYH2_k127_6981287_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.81e-227 709.0
PYH2_k127_6981287_1 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002635 461.0
PYH2_k127_6981287_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007249 287.0
PYH2_k127_6981287_3 peroxiredoxin activity K03564,K07638 - 1.11.1.15,2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000006257 222.0
PYH2_k127_6981287_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000001109 212.0
PYH2_k127_6981287_5 Belongs to the Fur family K03711,K09825 - - 0.00000000000000000000000000000000000000000000000002908 183.0
PYH2_k127_6981287_6 - - - - 0.0000000000000000000000000000000000000001701 154.0
PYH2_k127_6981287_7 GYD domain - - - 0.00000000000000000000000000000000000005538 145.0
PYH2_k127_6981287_8 AhpC/TSA family K03386 - 1.11.1.15 0.000000000000000008809 83.0
PYH2_k127_6981287_9 Rubredoxin - - - 0.00000000000000003043 85.0
PYH2_k127_7079392_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 368.0
PYH2_k127_7079392_1 Sirohaem biosynthesis protein central K02304 - 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000000000000000202 176.0
PYH2_k127_7079392_2 Binding-protein-dependent transport system inner membrane component K02026 - - 0.000000000005682 65.0
PYH2_k127_7079392_3 Tetratricopeptide repeat - - - 0.00000000009434 71.0
PYH2_k127_7079392_4 - - - - 0.00000001499 64.0
PYH2_k127_7160282_0 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 353.0
PYH2_k127_7160282_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000002578 270.0
PYH2_k127_7160282_2 phosphoesterase RecJ domain protein K06881 GO:0008150,GO:0040007 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000001702 250.0
PYH2_k127_7160282_3 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000002507 110.0
PYH2_k127_7160282_4 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000006068 89.0
PYH2_k127_7160282_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000004284 64.0
PYH2_k127_7163953_0 prenyltransferase activity K03186,K16875 GO:0003674,GO:0003824,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0008694,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000001772 214.0
PYH2_k127_7163953_1 Domain of unknown function (DUF4405) - - - 0.0000000000000000000000000000000000000000000000000004086 191.0
PYH2_k127_7163953_2 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000004257 174.0
PYH2_k127_7163953_3 deoxyhypusine monooxygenase activity - - - 0.000000000000000000009543 100.0
PYH2_k127_7163953_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.00000000001984 66.0
PYH2_k127_7201276_0 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002273 385.0
PYH2_k127_7201276_1 denitrification pathway K03532 - - 0.0006574 46.0
PYH2_k127_7245167_0 PFAM Type II secretion system protein E K02454 - - 3.885e-198 629.0
PYH2_k127_7245167_1 General secretion pathway protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003971 278.0
PYH2_k127_7245167_2 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000001471 212.0
PYH2_k127_7245167_3 General secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.00000000000000000002951 100.0
PYH2_k127_7245167_4 Prokaryotic N-terminal methylation motif K02457 - - 0.00000000000000005296 87.0
PYH2_k127_7245167_5 PFAM General secretion pathway protein K K02460 - - 0.0000002657 57.0
PYH2_k127_7245167_6 Prokaryotic N-terminal methylation motif K02458 - - 0.000001405 55.0
PYH2_k127_7273328_0 Major Facilitator Superfamily K08223 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 465.0
PYH2_k127_7273328_1 Uncharacterised protein family (UPF0227) K07000 - - 0.000000000000000000000000000000000004465 145.0
PYH2_k127_7273328_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K07003 - - 0.000000000000000000000000000004484 129.0
PYH2_k127_7273328_3 Cold shock K03704 - - 0.0000000000000000000000001296 108.0
PYH2_k127_7293362_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 283.0
PYH2_k127_7293362_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000001839 240.0
PYH2_k127_7293362_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.00000000000000000000000000000000000000000000121 171.0
PYH2_k127_7294500_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 361.0
PYH2_k127_7294500_1 Aminotransferase class I and II K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003498 285.0
PYH2_k127_7296986_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 347.0
PYH2_k127_7296986_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005453 269.0
PYH2_k127_7296986_2 - - - - 0.000000000000000000001998 97.0
PYH2_k127_7304290_0 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 494.0
PYH2_k127_7304290_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 339.0
PYH2_k127_7304290_2 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001276 292.0
PYH2_k127_7304290_3 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000313 272.0
PYH2_k127_7304290_4 Protein phosphatase 2C domain K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000007989 246.0
PYH2_k127_7304290_5 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000002012 101.0
PYH2_k127_7304290_6 STAS domain K04749 - - 0.000000000000000000002146 97.0
PYH2_k127_7304290_7 PHB de-polymerase C-terminus K03821 - - 0.000002578 49.0
PYH2_k127_732926_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.788e-203 639.0
PYH2_k127_732926_1 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 544.0
PYH2_k127_732926_2 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 472.0
PYH2_k127_732926_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 329.0
PYH2_k127_732926_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.00000000000000000000000000000000000000000000000000002542 197.0
PYH2_k127_732926_5 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000004198 130.0
PYH2_k127_7341644_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 588.0
PYH2_k127_7341644_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 575.0
PYH2_k127_7341644_10 Papain-like cysteine protease AvrRpt2 - - - 0.000000000000000000000000000000000000002944 154.0
PYH2_k127_7341644_11 photosynthesis - - - 0.00000000000000000000000000000002261 132.0
PYH2_k127_7341644_12 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752,K13818 - 2.7.7.77 0.0000000000000000000000000000002379 130.0
PYH2_k127_7341644_13 - - - - 0.0000000000000000000000000000285 122.0
PYH2_k127_7341644_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000002463 92.0
PYH2_k127_7341644_2 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 427.0
PYH2_k127_7341644_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 325.0
PYH2_k127_7341644_4 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 290.0
PYH2_k127_7341644_5 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000004259 231.0
PYH2_k127_7341644_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000001041 229.0
PYH2_k127_7341644_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000001939 216.0
PYH2_k127_7341644_8 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000007804 177.0
PYH2_k127_7341644_9 Binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001197 157.0
PYH2_k127_7546704_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 597.0
PYH2_k127_7546704_1 AAA domain K02450,K12283 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 295.0
PYH2_k127_7546704_2 TIGRFAM TIGR00268 family protein K06864 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001741 286.0
PYH2_k127_7546704_3 Protein conserved in bacteria - - - 0.000000000000000000000000000002952 131.0
PYH2_k127_7546704_4 COG1522 Transcriptional regulators - - - 0.0000000003442 63.0
PYH2_k127_7552859_0 Type II and III secretion system protein K02453 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 537.0
PYH2_k127_7552859_1 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 452.0
PYH2_k127_7552859_2 SMART PDZ DHR GLGF domain protein K02452 - - 0.000000000000000000000000000000000000000000875 168.0
PYH2_k127_7552859_3 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000002433 124.0
PYH2_k127_7563936_0 General secretory system II, protein E domain protein K02652 - - 4.562e-215 685.0
PYH2_k127_7563936_1 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 553.0
PYH2_k127_7563936_2 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.000000000000000000000000000000000000000000000000003323 186.0
PYH2_k127_7565906_0 Belongs to the glycosyl hydrolase 5 (cellulase A) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008172 467.0
PYH2_k127_7565906_1 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002147 229.0
PYH2_k127_7565906_2 phosphorelay signal transduction system - - - 0.00000000000000000000001627 106.0
PYH2_k127_758670_0 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 589.0
PYH2_k127_758670_1 ATP synthase subunit D K02120 - - 0.00000000000000000000000000000000000000000000000000000000000000004434 231.0
PYH2_k127_758670_2 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000001516 111.0
PYH2_k127_7639272_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000502 405.0
PYH2_k127_7639272_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 383.0
PYH2_k127_7639272_2 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000002568 231.0
PYH2_k127_7644579_0 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 351.0
PYH2_k127_7644579_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 329.0
PYH2_k127_7644579_2 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 297.0
PYH2_k127_7644579_3 Glycosyltransferase like family 2 - - - 0.000000000000000000000000000002977 135.0
PYH2_k127_7644579_4 aminoglycoside K00662 - 2.3.1.81 0.00000000000000000001452 105.0
PYH2_k127_7644579_5 Lipid A core - O-antigen ligase and K02847 - - 0.000000007272 66.0
PYH2_k127_7654009_0 Ion channel K10716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008586 350.0
PYH2_k127_7654009_1 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 306.0
PYH2_k127_7654009_2 Ribosomal protein L11 methyltransferase K02687 - - 0.0000000000000000000000000000000000000000000001436 179.0
PYH2_k127_7654009_3 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000006105 142.0
PYH2_k127_7677738_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 8.939e-276 857.0
PYH2_k127_7677738_1 K transport systems K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 375.0
PYH2_k127_7677738_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000003269 129.0
PYH2_k127_7685743_0 Putative RNA methylase family UPF0020 K07444,K12297 - 2.1.1.173,2.1.1.264 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004226 495.0
PYH2_k127_7685743_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000000000000000000000000000000000000000001431 196.0
PYH2_k127_7774651_0 phosphatase activity K20881 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0008477,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016798,GO:0016799,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050483,GO:0050484 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
PYH2_k127_7774651_1 inositol monophosphate 1-phosphatase activity K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000001235 239.0
PYH2_k127_7780893_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 5.374e-258 807.0
PYH2_k127_7780893_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.353e-211 665.0
PYH2_k127_7780893_2 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002594 421.0
PYH2_k127_7780893_3 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 284.0
PYH2_k127_7780893_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000001331 231.0
PYH2_k127_7780893_5 ACT domain - - - 0.00000000000000000000000000000000000000000000000000000000004934 207.0
PYH2_k127_77971_0 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000002037 250.0
PYH2_k127_77971_1 PFAM Peptidase M23 - - - 0.0000000000000000000000000000000000000007817 158.0
PYH2_k127_780019_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002619 266.0
PYH2_k127_780019_1 PFAM CheW domain protein K03408 - - 0.000000000000000000004125 100.0
PYH2_k127_780019_2 Chemotaxis sensory transducer K03406 - - 0.000001215 57.0
PYH2_k127_7816928_0 Domain in cystathionine beta-synthase and other proteins. K07182 - - 3.847e-226 717.0
PYH2_k127_7816928_1 glycolate transport K14393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 465.0
PYH2_k127_7816928_2 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 347.0
PYH2_k127_7816928_3 Sigma-54 interaction domain K07714 - - 0.0000000000000000000000000000000000000009032 153.0
PYH2_k127_7816928_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000005158 151.0
PYH2_k127_7816928_5 membrane - - - 0.000000000000000000000009178 102.0
PYH2_k127_7828676_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001671 248.0
PYH2_k127_7828676_1 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000003864 239.0
PYH2_k127_7828676_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000002644 95.0
PYH2_k127_7828676_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000001889 81.0
PYH2_k127_7828676_4 Mn2 dependent serine threonine protein kinase - - - 0.0000000000000005078 79.0
PYH2_k127_7893229_0 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003518 583.0
PYH2_k127_7893229_1 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 319.0
PYH2_k127_7893229_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000232 265.0
PYH2_k127_7893229_3 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000001465 254.0
PYH2_k127_7893229_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000002664 123.0
PYH2_k127_7893229_6 lyase activity - - - 0.000000000000000001174 93.0
PYH2_k127_7893229_7 metalloendopeptidase activity K03799 - - 0.0000000000000001368 90.0
PYH2_k127_7893229_8 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000003403 64.0
PYH2_k127_7895266_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 582.0
PYH2_k127_7895266_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 511.0
PYH2_k127_7895266_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 356.0
PYH2_k127_7895266_3 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001835 281.0
PYH2_k127_7895266_4 PFAM General secretion pathway protein K K02460 - - 0.00000000000000000000000000000000001292 149.0
PYH2_k127_7895266_5 PFAM Fimbrial assembly K02461 - - 0.0000000000000008514 91.0
PYH2_k127_7895266_6 Type II secretion system (T2SS), protein M subtype b - - - 0.000000003048 65.0
PYH2_k127_7895266_7 Pfam:N_methyl_2 K02459 - - 0.000002217 57.0
PYH2_k127_7944529_0 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1642.0
PYH2_k127_7944529_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1316.0
PYH2_k127_7944529_2 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 342.0
PYH2_k127_7944529_3 Participates in transcription elongation, termination and antitermination K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003023 267.0
PYH2_k127_7944529_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000001519 217.0
PYH2_k127_7944529_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000001959 196.0
PYH2_k127_7944529_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000006853 145.0
PYH2_k127_7944529_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000001585 80.0
PYH2_k127_7944529_8 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000467 74.0
PYH2_k127_7944529_9 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000006944 63.0
PYH2_k127_7970901_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001423 246.0
PYH2_k127_7970901_1 cysteine-tRNA ligase activity - - - 0.0000000000000000000000000002129 119.0
PYH2_k127_7976147_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.274e-215 674.0
PYH2_k127_7976147_1 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003827 317.0
PYH2_k127_7976147_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000001782 202.0
PYH2_k127_7976147_3 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000003412 177.0
PYH2_k127_7976147_4 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000008081 134.0
PYH2_k127_7976147_5 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001437 67.0
PYH2_k127_7976147_6 binds to the 23S rRNA K02876 - - 0.0000000239 55.0
PYH2_k127_808420_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 330.0
PYH2_k127_808420_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000001143 220.0
PYH2_k127_808420_2 PFAM Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000005519 210.0
PYH2_k127_808420_3 DDE superfamily endonuclease - - - 0.0000006492 53.0
PYH2_k127_8139102_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 381.0
PYH2_k127_8139102_1 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 344.0
PYH2_k127_8139102_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 314.0
PYH2_k127_8139102_3 HEAT repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 316.0
PYH2_k127_8139102_4 GAF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000301 291.0
PYH2_k127_8139102_5 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000002582 174.0
PYH2_k127_8139102_6 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000001704 163.0
PYH2_k127_8139102_7 Two component signalling adaptor domain K03408 - - 0.000000000000000000000000000003875 126.0
PYH2_k127_8139102_8 - - - - 0.00000000007797 67.0
PYH2_k127_8201479_0 PFAM peptidase K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 287.0
PYH2_k127_8201479_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000005297 209.0
PYH2_k127_8201479_2 Oligoendopeptidase F K08602 - - 0.0000006149 59.0
PYH2_k127_8207720_0 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 387.0
PYH2_k127_8207720_1 - K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 391.0
PYH2_k127_8207720_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599,K14080 - 2.1.1.246,4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 307.0
PYH2_k127_8207720_3 PFAM LemA family protein K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 290.0
PYH2_k127_8207720_4 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001879 284.0
PYH2_k127_8207720_5 Pfam:TPM K08988 - - 0.000000000000000000000000000000000000000000000000000000000006496 214.0
PYH2_k127_8207720_6 Methyltransferase MtaA K14080 - 2.1.1.246 0.0000000000000000000000000000000000000000000000000000002823 206.0
PYH2_k127_8207720_7 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000002571 138.0
PYH2_k127_8207720_8 - - - - 0.0000000000000000000000000000009708 125.0
PYH2_k127_8207720_9 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.000000000000007633 81.0
PYH2_k127_8240265_0 Aminotransferase class-III K01845 - 5.4.3.8 6.556e-208 653.0
PYH2_k127_8240265_1 Polysulphide reductase, NrfD - - - 1.162e-196 619.0
PYH2_k127_8240265_2 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 470.0
PYH2_k127_8240265_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009623 429.0
PYH2_k127_8240265_4 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008624 245.0
PYH2_k127_8240265_5 peptidyl-prolyl isomerase K01802,K03769,K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000002207 205.0
PYH2_k127_8240265_6 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000008636 152.0
PYH2_k127_8240265_7 Transcriptional regulator - - - 0.00000000000000000000000000000000001447 143.0
PYH2_k127_8240265_8 Cytochrome c - - - 0.0000002052 55.0
PYH2_k127_8279618_0 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003564 409.0
PYH2_k127_8279618_1 Chemotaxis phosphatase CheX - - - 0.0000000000007908 73.0
PYH2_k127_8279618_2 Tetratricopeptide repeats - - - 0.00000000001258 76.0
PYH2_k127_8281180_0 FAD binding domain K00278 - 1.4.3.16 5.285e-207 657.0
PYH2_k127_8281180_1 Belongs to the ABC transporter superfamily K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002822 349.0
PYH2_k127_8281180_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000004978 175.0
PYH2_k127_8281180_3 Thioredoxin-like - - - 0.0000000000000000000000000000000000001131 147.0
PYH2_k127_8281180_4 ABC transporter, ATP-binding protein K02032,K10823 - - 0.00001035 48.0
PYH2_k127_8301960_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 6.335e-200 630.0
PYH2_k127_8301960_1 Transglutaminase-like superfamily K22452 - 2.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 495.0
PYH2_k127_8301960_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 323.0
PYH2_k127_8301960_3 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000004872 209.0
PYH2_k127_8301960_4 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 - 3.2.2.26 0.0000000000000000000000000000000000000000000000000000002424 201.0
PYH2_k127_8301960_5 lipolytic protein G-D-S-L family - - - 0.0000000000000000000000000000000000000003291 154.0
PYH2_k127_8318311_0 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005467 264.0
PYH2_k127_8318311_1 Thioesterase K18700 - 3.1.2.29 0.00000000000000000000000000000000000000000000000000000001205 200.0
PYH2_k127_8318311_2 aminopeptidase N - - - 0.0000000000000000000000000000000000000000006757 168.0
PYH2_k127_8318311_3 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000005247 132.0
PYH2_k127_8361462_0 Hypothetical methyltransferase - - - 0.0000000000778 72.0
PYH2_k127_8361462_1 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.0001764 46.0
PYH2_k127_839024_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 4.686e-254 788.0
PYH2_k127_839024_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000007324 148.0
PYH2_k127_839024_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000004064 122.0
PYH2_k127_8444635_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000001798 76.0
PYH2_k127_8444635_2 - - - - 0.0000000001449 66.0
PYH2_k127_8468395_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009859 312.0
PYH2_k127_8468395_1 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009504 287.0
PYH2_k127_8468395_2 4 iron, 4 sulfur cluster binding K00176 - 1.2.7.3 0.0001846 44.0
PYH2_k127_8470286_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 356.0
PYH2_k127_8470286_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000191 164.0
PYH2_k127_8475216_0 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335 - 1.6.5.3 1.956e-317 981.0
PYH2_k127_8475216_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 366.0
PYH2_k127_8475216_2 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000002968 197.0
PYH2_k127_848821_0 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006138 428.0
PYH2_k127_848821_1 Thiamine biosynthesis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 301.0
PYH2_k127_848821_2 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004582 282.0
PYH2_k127_8545297_0 Domain of unknown function (DUF4921) K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005126 330.0
PYH2_k127_8545297_1 oxidoreductase K10960 - 1.3.1.111,1.3.1.83 0.00000000000000000000000000000000000000000000000000000000000000002252 239.0
PYH2_k127_8545297_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000002651 182.0
PYH2_k127_8545297_3 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000002834 155.0
PYH2_k127_8545297_4 Universal stress protein family - - - 0.00000000000000000000000000000000000023 145.0
PYH2_k127_8545297_5 proteolysis K03665 - - 0.00000000000000000000000000002465 123.0
PYH2_k127_8545297_6 energy transducer activity K03832 - - 0.0000000419 63.0
PYH2_k127_8545307_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 305.0
PYH2_k127_8545307_1 PINc domain ribonuclease K09006 - - 0.000000000000000000000000000000000000000000000000000000000000000397 227.0
PYH2_k127_8545307_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000002257 123.0
PYH2_k127_8545307_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000003485 93.0
PYH2_k127_8559790_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 6.315e-272 859.0
PYH2_k127_8559790_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 326.0
PYH2_k127_8559790_2 heat shock protein binding - - - 0.000000000002406 75.0
PYH2_k127_8567685_0 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 285.0
PYH2_k127_8567685_1 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000004452 232.0
PYH2_k127_8567685_2 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000002217 128.0
PYH2_k127_8567685_3 Belongs to the HesB IscA family K15724 - - 0.00000006323 55.0
PYH2_k127_8599638_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 1.316e-276 875.0
PYH2_k127_8599638_1 diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000001767 271.0
PYH2_k127_8599638_2 DNA polymerase X family K02347,K04477 - - 0.0000000000000000000001039 99.0
PYH2_k127_8613928_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 516.0
PYH2_k127_8613928_1 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 491.0
PYH2_k127_8613928_2 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001698 370.0
PYH2_k127_8613928_3 Putative Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 335.0
PYH2_k127_8613928_4 metal-dependent enzyme K09153 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 295.0
PYH2_k127_8613928_5 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002636 267.0
PYH2_k127_8613928_6 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003673 251.0
PYH2_k127_8613928_7 Part of a membrane complex involved in electron transport K03613 - - 0.000000000000000000000000000000000000000000000000000000000000000000001581 242.0
PYH2_k127_8613928_8 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000006567 113.0
PYH2_k127_8613928_9 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000001287 114.0
PYH2_k127_8634792_0 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006236 428.0
PYH2_k127_8634792_1 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000000006261 201.0
PYH2_k127_8634792_2 PFAM CBS domain K07182 - - 0.000000000000000000000532 101.0
PYH2_k127_8639010_0 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 504.0
PYH2_k127_8639010_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000002831 166.0
PYH2_k127_8639010_3 SMART Elongator protein 3 MiaB NifB K22226 - - 0.0000001466 53.0
PYH2_k127_866675_0 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 350.0
PYH2_k127_866675_1 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006198 265.0
PYH2_k127_866675_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.0000000000000000000000000001887 117.0
PYH2_k127_866675_3 ubiE/COQ5 methyltransferase family - - - 0.00006065 51.0
PYH2_k127_8679909_0 GAF domain - - - 4.487e-206 674.0
PYH2_k127_8679909_1 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000001312 164.0
PYH2_k127_8679909_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000002044 170.0
PYH2_k127_8690112_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300,K08301 - 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 439.0
PYH2_k127_8690112_1 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.0000000000000000000000000001641 119.0
PYH2_k127_8690112_2 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000004115 67.0
PYH2_k127_8799665_0 hydrogenase large subunit K05922,K06281 - 1.12.5.1,1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 508.0
PYH2_k127_8799665_1 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 321.0
PYH2_k127_8799665_2 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002684 271.0
PYH2_k127_8799665_3 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000003712 258.0
PYH2_k127_8799665_4 GAF domain K02584 - - 0.000000000000000000000000000000000000000000000000000009915 193.0
PYH2_k127_8799665_5 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000000000000002993 140.0
PYH2_k127_8799665_6 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000007972 98.0
PYH2_k127_8818210_0 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 293.0
PYH2_k127_8818210_1 sodium-dependent phosphate transmembrane transporter activity K14683 - - 0.0000000000000000000003779 100.0
PYH2_k127_8818210_2 Type II secretion system protein B K02451 - - 0.00000000000000000009304 100.0
PYH2_k127_8818210_3 deoxyhypusine monooxygenase activity - - - 0.0000000000000000001144 99.0
PYH2_k127_885588_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 434.0
PYH2_k127_885588_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004813 273.0
PYH2_k127_885588_2 membrane - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000001056 205.0
PYH2_k127_885588_3 Belongs to the HesB IscA family K15724 - - 0.0000000000000000000000000001977 117.0
PYH2_k127_885588_4 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.000000001281 59.0
PYH2_k127_8862290_0 phosphorelay sensor kinase activity K03320,K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 379.0
PYH2_k127_8862290_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 296.0
PYH2_k127_8862290_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001232 266.0
PYH2_k127_8862290_3 phosphohistidine phosphatase, SixA K03574,K08296 - 3.6.1.55 0.000000000000000000000000000000000000002001 151.0
PYH2_k127_8909766_0 Protein of unknown function (DUF2950) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 325.0
PYH2_k127_8909766_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002614 285.0
PYH2_k127_8909766_2 Mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002074 297.0
PYH2_k127_8909766_3 - - - - 0.000000000006733 74.0
PYH2_k127_9020061_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000036 450.0
PYH2_k127_9020061_1 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
PYH2_k127_9020061_2 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 289.0
PYH2_k127_9020061_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000005204 207.0
PYH2_k127_9020061_4 RNA recognition motif - - - 0.000000000000000000000000002347 115.0
PYH2_k127_9020061_5 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000002921 94.0
PYH2_k127_9020061_6 structural constituent of ribosome K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000005576 63.0
PYH2_k127_9020061_7 Membrane - - - 0.00000001887 58.0
PYH2_k127_9116029_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1385.0
PYH2_k127_9116029_1 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 533.0
PYH2_k127_9116029_2 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 394.0
PYH2_k127_9116029_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000002107 153.0
PYH2_k127_9116029_4 Nitrate reductase delta subunit - - - 0.00000000000000000000000007589 117.0
PYH2_k127_9116029_5 cytochrome c oxidase subunit II K02275 - 1.9.3.1 0.000000002565 64.0
PYH2_k127_9124236_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537,K01539 - 3.6.3.8,3.6.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 578.0
PYH2_k127_9124236_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000003611 169.0
PYH2_k127_9126690_0 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 494.0
PYH2_k127_9126690_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 372.0
PYH2_k127_9126690_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 310.0
PYH2_k127_9126690_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.00000000000000000000000000000000000000000000000000000000000002833 220.0
PYH2_k127_9126690_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000006877 57.0
PYH2_k127_9152447_0 sister chromatid segregation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 555.0
PYH2_k127_9152447_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 263.0
PYH2_k127_9152447_3 IMP dehydrogenase activity - - - 0.0006291 42.0
PYH2_k127_919840_0 Uncharacterised nucleotidyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008375 327.0
PYH2_k127_919840_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002749 261.0
PYH2_k127_919840_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.00000000000000000000000000000000000000000000000000205 189.0
PYH2_k127_919840_3 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000001206 137.0
PYH2_k127_9200757_0 Conserved hypothetical protein 698 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 579.0
PYH2_k127_9200757_1 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 288.0
PYH2_k127_9200757_2 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003071 264.0
PYH2_k127_9200757_3 PFAM Glycosyl hydrolase family 3 N terminal domain K01207,K05349 - 3.2.1.21,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000007358 224.0
PYH2_k127_9200757_4 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000001492 195.0
PYH2_k127_9200757_5 - - - - 0.00000000000000000000000000000000000000000000000001366 186.0
PYH2_k127_9200757_6 PFAM Methylamine - - - 0.0000000000000009577 84.0
PYH2_k127_9200757_7 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000001533 62.0
PYH2_k127_9200757_8 Redoxin - - - 0.0002104 48.0
PYH2_k127_9210694_0 Elongation factor SelB, winged helix K03833 - - 1.892e-209 670.0
PYH2_k127_9210694_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 383.0
PYH2_k127_9210694_2 Carbon-nitrogen hydrolase K03820 - - 0.0000000000000000000000000000000349 131.0
PYH2_k127_9210694_3 OsmC-like protein K07397 - - 0.000000000000000000000004226 109.0
PYH2_k127_9218375_0 response regulator receiver K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 364.0
PYH2_k127_9218375_1 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 344.0
PYH2_k127_9218375_2 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000001025 197.0
PYH2_k127_9221183_0 myo-inosose-2 dehydratase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008752 314.0
PYH2_k127_9221183_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000003709 197.0
PYH2_k127_9221183_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000000006778 167.0
PYH2_k127_9221183_3 Putative regulatory protein - - - 0.00000000000000000000004719 101.0
PYH2_k127_9231998_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 6.55e-243 763.0
PYH2_k127_9231998_1 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000000000000000000000000000000000000000000002252 178.0
PYH2_k127_9231998_2 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000007436 101.0
PYH2_k127_9261973_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.042e-305 945.0
PYH2_k127_9261973_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 1.176e-260 816.0
PYH2_k127_9261973_10 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000000000000000000000004608 147.0
PYH2_k127_9261973_11 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000192 151.0
PYH2_k127_9261973_13 cyclic nucleotide binding K00384,K01420 - 1.8.1.9 0.00000000000000000000000285 105.0
PYH2_k127_9261973_17 - - - - 0.0003371 47.0
PYH2_k127_9261973_2 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 377.0
PYH2_k127_9261973_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 359.0
PYH2_k127_9261973_4 Epimerase K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 326.0
PYH2_k127_9261973_5 Asparagine synthase K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 311.0
PYH2_k127_9261973_6 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003116 274.0
PYH2_k127_9261973_7 ATPase activity K02010,K02049,K02068,K02071,K06857,K10112 - 3.6.3.30,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 253.0
PYH2_k127_9261973_8 COG1541 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000389 261.0
PYH2_k127_9261973_9 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000003313 166.0
PYH2_k127_9263048_0 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002016 262.0
PYH2_k127_9263048_1 kinase activity K01006,K01007 - 2.7.9.1,2.7.9.2 0.000000000000000000000000000000000000000000000000000000000005039 216.0
PYH2_k127_9263048_2 IMP dehydrogenase activity - - - 0.0000000000000000000000000000001966 129.0
PYH2_k127_9263048_3 response regulator, receiver - - - 0.000000000000000000000000003042 115.0
PYH2_k127_9267380_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 413.0
PYH2_k127_9267380_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000794 385.0
PYH2_k127_9267380_2 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000002225 139.0
PYH2_k127_9267380_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000001161 112.0
PYH2_k127_9267380_4 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.000000000000000000008557 92.0
PYH2_k127_9276822_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1079.0
PYH2_k127_9276822_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.151e-278 869.0
PYH2_k127_9276822_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.48e-209 660.0
PYH2_k127_9276822_3 phenylalanine-tRNA ligase activity K01890 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007607 588.0
PYH2_k127_9276822_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 459.0
PYH2_k127_9276822_5 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 330.0
PYH2_k127_9276822_6 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000001646 181.0
PYH2_k127_9276822_7 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0000900,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006355,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0016020,GO:0016043,GO:0017148,GO:0019219,GO:0019222,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0030371,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045182,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065003,GO:0065007,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0080090,GO:0090079,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:1990904,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000002253 152.0
PYH2_k127_9276822_8 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000009883 88.0
PYH2_k127_9276822_9 mercury ion transmembrane transporter activity K07213 - - 0.0000000000000000818 81.0
PYH2_k127_9292041_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02474 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 575.0
PYH2_k127_9292041_1 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002142 282.0
PYH2_k127_9292041_2 Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC) K00564,K15460 - 2.1.1.172,2.1.1.223 0.0000000000000000000000000000000000000000000000000000000000000003371 228.0
PYH2_k127_9304177_0 4Fe-4S dicluster domain K00124 GO:0005575,GO:0005623,GO:0009326,GO:0032991,GO:0042597,GO:0044464,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 322.0
PYH2_k127_9304177_1 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.0000000000000000000000000000000000000000000000000000000001336 209.0
PYH2_k127_9304177_2 Prokaryotic cytochrome b561 K00127 - - 0.000000000000000000000000000000000009091 143.0
PYH2_k127_952345_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1054.0
PYH2_k127_952345_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 310.0
PYH2_k127_952345_2 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000008861 237.0
PYH2_k127_970583_0 type II secretion system protein E K02454 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 570.0
PYH2_k127_970583_1 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 365.0
PYH2_k127_970583_2 sugar transferase K00996 - 2.7.8.6 0.00000000000000000000000000000000000000000000000001917 181.0
PYH2_k127_970583_3 Prokaryotic N-terminal methylation motif - - - 0.000009327 55.0
PYH2_k127_970583_4 Prokaryotic N-terminal methylation motif K02458 - - 0.0009897 48.0