Overview

ID MAG03210
Name PYH2_bin.71
Sample SMP0074
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Sulfuricellaceae
Genus Sulfuricella
Species
Assembly information
Completeness (%) 76.33
Contamination (%) 5.01
GC content (%) 57.0
N50 (bp) 7,469
Genome size (bp) 2,335,662

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2484

Gene name Description KEGG GOs EC E-value Score Sequence
PYH2_k127_1007149_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1441.0
PYH2_k127_1007149_1 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 332.0
PYH2_k127_1007149_2 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008148 296.0
PYH2_k127_1007149_3 Thioredoxin K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 287.0
PYH2_k127_1007149_4 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008558 269.0
PYH2_k127_1007149_5 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001134 246.0
PYH2_k127_1007149_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.00000000000000000000000000000000000000000000007351 169.0
PYH2_k127_1007149_7 Sulfurtransferase - - - 0.000000000000000000000000000000000000201 141.0
PYH2_k127_101926_0 Putative diguanylate phosphodiesterase - - - 0.0 1273.0
PYH2_k127_101926_1 transglycosylase K08309 - - 0.0 1185.0
PYH2_k127_101926_10 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.00005667 50.0
PYH2_k127_101926_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.848e-295 906.0
PYH2_k127_101926_3 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 2.371e-246 764.0
PYH2_k127_101926_4 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005941 598.0
PYH2_k127_101926_5 epimerase dehydratase K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002025 552.0
PYH2_k127_101926_6 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006576 394.0
PYH2_k127_101926_7 (ABC) transporter K05685,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 343.0
PYH2_k127_101926_8 Glycine zipper - - - 0.0000000000000000000000000000000000000000000000000000000001175 209.0
PYH2_k127_101926_9 Outer membrane lipoprotein Slp K07285 - - 0.000000000000000000000000000000000000000000009801 169.0
PYH2_k127_1026770_0 May be involved in recombination K03554 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 544.0
PYH2_k127_1026770_1 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000165 486.0
PYH2_k127_1026770_2 Uncharacterised protein family (UPF0160) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 430.0
PYH2_k127_1031220_0 Diguanylate cyclase - - - 0.0 1159.0
PYH2_k127_1031220_1 Histidine kinase K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006358 589.0
PYH2_k127_1031220_2 Diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 578.0
PYH2_k127_1031220_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000667 317.0
PYH2_k127_1031220_4 Histidine Phosphotransfer domain - - - 0.000000000000000000000000000000000000000006149 164.0
PYH2_k127_1031220_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000001281 66.0
PYH2_k127_1044550_0 transport system - - - 1.008e-267 835.0
PYH2_k127_1044550_1 Abc transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 443.0
PYH2_k127_1044550_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 437.0
PYH2_k127_1044550_3 Domain of unknown function (DUF4340) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 349.0
PYH2_k127_1044550_4 SMART Tetratricopeptide domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001856 250.0
PYH2_k127_1071764_0 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 1.008e-225 704.0
PYH2_k127_1071764_1 type I secretion outer membrane protein, TolC K12340 - - 1.92e-221 692.0
PYH2_k127_1071764_2 lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 565.0
PYH2_k127_1071764_3 Glycosyl transferase family 2 K12984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 412.0
PYH2_k127_1071764_4 protein-L-isoaspartate(D-aspartate) O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000324 405.0
PYH2_k127_1071764_5 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000000000000000000000006173 218.0
PYH2_k127_110030_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 2305.0
PYH2_k127_110030_1 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 1.752e-314 965.0
PYH2_k127_110030_10 PFAM cytochrome c, class I K08738 - - 0.000000000000000000361 93.0
PYH2_k127_110030_2 Histidine kinase - - - 5.501e-302 980.0
PYH2_k127_110030_3 molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005669 494.0
PYH2_k127_110030_4 SMART Signal transduction response regulator, receiver region K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 414.0
PYH2_k127_110030_5 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004481 336.0
PYH2_k127_110030_6 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000005253 251.0
PYH2_k127_110030_7 Nitrate reductase K00373 - - 0.0000000000000000000000000000000000000000000000000000000000000000001595 233.0
PYH2_k127_110030_8 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 - - 0.00000000000000000000000000000000000000000000005164 173.0
PYH2_k127_110030_9 Major Facilitator Superfamily K02575 - - 0.000000000000000000000000000000000000000000001061 165.0
PYH2_k127_1109000_0 CoA-binding domain protein K09181 - - 0.0 1677.0
PYH2_k127_1109000_1 AAA domain K07028 - - 5.073e-195 612.0
PYH2_k127_1109000_2 histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004053 603.0
PYH2_k127_1109000_3 Domain of unknown function (DUF4337) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004119 259.0
PYH2_k127_1109000_4 PAP2 superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000002677 241.0
PYH2_k127_1109000_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000008058 184.0
PYH2_k127_1109000_6 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000000000000000000002464 173.0
PYH2_k127_1109000_7 - - - - 0.00000000000000000000000000000000000000002915 162.0
PYH2_k127_1129238_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 3.321e-228 708.0
PYH2_k127_1129238_1 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004708 335.0
PYH2_k127_1129238_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000001786 136.0
PYH2_k127_1158511_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 3.734e-218 679.0
PYH2_k127_1158511_1 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 6.206e-216 670.0
PYH2_k127_1158511_2 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002112 469.0
PYH2_k127_1158511_3 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 341.0
PYH2_k127_1187468_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 3.947e-207 646.0
PYH2_k127_1187468_1 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 464.0
PYH2_k127_1187468_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007925 330.0
PYH2_k127_1187468_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000001103 100.0
PYH2_k127_1198837_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 520.0
PYH2_k127_1198837_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005925 401.0
PYH2_k127_1198837_2 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 350.0
PYH2_k127_1198837_3 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 339.0
PYH2_k127_1198837_4 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000000000000000000000000000000000000000000000000001347 213.0
PYH2_k127_1198837_5 Protein of unknown function (DUF504) - - - 0.0000000000000000000000000000004073 123.0
PYH2_k127_1199706_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1352.0
PYH2_k127_1199706_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 576.0
PYH2_k127_1199706_2 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 474.0
PYH2_k127_1199706_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006182 282.0
PYH2_k127_1199706_4 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 278.0
PYH2_k127_1199706_5 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000000000000000000000000000000000000000002142 236.0
PYH2_k127_1199706_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000000000005239 169.0
PYH2_k127_1201394_0 DNA polymerase III is a complex multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3 to 5 exonuclease activity K02343 - 2.7.7.7 1.934e-298 925.0
PYH2_k127_1201394_1 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 5.365e-280 863.0
PYH2_k127_1201394_2 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 1.904e-196 617.0
PYH2_k127_1201394_3 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 494.0
PYH2_k127_1201394_4 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 401.0
PYH2_k127_1201394_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006773 390.0
PYH2_k127_1201394_6 ABC-type transport auxiliary lipoprotein component K18480 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 319.0
PYH2_k127_1201394_7 ATPases associated with a variety of cellular activities K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 295.0
PYH2_k127_1201394_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000000000000000000000000006061 205.0
PYH2_k127_1201394_9 aminopeptidase activity - - - 0.0000000000000000003721 87.0
PYH2_k127_1202929_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.051e-272 846.0
PYH2_k127_1202929_1 Peptidoglycan polymerase that is essential for cell division K03588 - - 2.879e-232 722.0
PYH2_k127_1202929_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 4.351e-215 670.0
PYH2_k127_1202929_3 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 606.0
PYH2_k127_1202929_4 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000002576 245.0
PYH2_k127_1202929_5 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000006908 227.0
PYH2_k127_1248744_0 orn lys arg decarboxylase K01584 - 4.1.1.19 0.0 1119.0
PYH2_k127_1248744_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 7.054e-229 711.0
PYH2_k127_1248744_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 493.0
PYH2_k127_1248744_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 400.0
PYH2_k127_1248744_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000001886 158.0
PYH2_k127_1269985_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 1953.0
PYH2_k127_1269985_1 COG0457 FOG TPR repeat - - - 0.0 1491.0
PYH2_k127_1269985_10 PFAM Transposase IS200 like - - - 0.00004934 48.0
PYH2_k127_1269985_2 COG0457 FOG TPR repeat - - - 0.0 1200.0
PYH2_k127_1269985_3 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005489 522.0
PYH2_k127_1269985_4 lytic transglycosylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 496.0
PYH2_k127_1269985_5 methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005074 348.0
PYH2_k127_1269985_6 ThiF family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001308 248.0
PYH2_k127_1269985_7 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000002858 218.0
PYH2_k127_1269985_8 UDP binding domain K02474 - - 0.00000000000000000000000000000000000000000000000000000003119 200.0
PYH2_k127_1269985_9 PEP-CTERM motif - - - 0.000000000000000000000000246 115.0
PYH2_k127_1305001_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 552.0
PYH2_k127_1305001_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006881 489.0
PYH2_k127_131674_0 phosphoenolpyruvate carboxykinase (diphosphate) activity K20370 - 4.1.1.38 1.737e-319 979.0
PYH2_k127_1321728_0 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 376.0
PYH2_k127_1321728_1 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000647 335.0
PYH2_k127_1321728_2 ATP:dephospho-CoA triphosphoribosyl transferase K13930 - 2.4.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 301.0
PYH2_k127_1321728_3 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 283.0
PYH2_k127_1321728_4 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.0000000000000000000000000000000000000000000000000000000006845 200.0
PYH2_k127_1332605_0 Domain of unknown function - - - 1.881e-231 725.0
PYH2_k127_1332605_1 Sodium:sulfate symporter transmembrane region K03319 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 463.0
PYH2_k127_1332605_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000002373 138.0
PYH2_k127_1332605_3 Domain of unknown function (DUF1906) - - - 0.00000001443 63.0
PYH2_k127_1335926_0 Asparagine synthase K01953 - 6.3.5.4 0.0 1148.0
PYH2_k127_1335926_1 Protein of unknown function (DUF3485) - - - 3.385e-249 773.0
PYH2_k127_1335926_2 glycosyl transferase group 1 - - - 3.706e-229 715.0
PYH2_k127_1335926_3 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 422.0
PYH2_k127_1335926_4 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003453 275.0
PYH2_k127_1337725_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 2.186e-252 781.0
PYH2_k127_1337725_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.865e-206 644.0
PYH2_k127_1344344_0 Diguanylate cyclase - - - 0.0 1367.0
PYH2_k127_1344344_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 4.536e-208 651.0
PYH2_k127_1344344_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008533 482.0
PYH2_k127_1344344_3 Short-chain dehydrogenase reductase (SDR) K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 456.0
PYH2_k127_1344344_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000001863 196.0
PYH2_k127_1344344_5 Prokaryotic cytochrome b561 - - - 0.00004626 46.0
PYH2_k127_1395841_0 Participates in both transcription termination and antitermination K02600 - - 1.137e-295 911.0
PYH2_k127_1395841_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.355e-243 769.0
PYH2_k127_1395841_2 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008785 273.0
PYH2_k127_1407740_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1638.0
PYH2_k127_1407740_1 Acetolactate synthase K01652 - 2.2.1.6 0.0 1133.0
PYH2_k127_1407740_10 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 292.0
PYH2_k127_1407740_11 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 285.0
PYH2_k127_1407740_12 PFAM RDD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000006607 237.0
PYH2_k127_1407740_14 Protein of unknown function (DUF3619) - - - 0.000000000000000000000000000000000000000000000000000000000003955 209.0
PYH2_k127_1407740_15 membrane - - - 0.000000000000000000000000000000000000000000000000000000225 196.0
PYH2_k127_1407740_16 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07226 - - 0.00000000000000000000000000000006594 124.0
PYH2_k127_1407740_17 Protein of unknown function (DUF3106) - - - 0.000000000000000000000000004887 117.0
PYH2_k127_1407740_18 - - - - 0.0000000000000000000000001448 109.0
PYH2_k127_1407740_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.894e-319 978.0
PYH2_k127_1407740_3 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.357e-311 956.0
PYH2_k127_1407740_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 1.048e-218 679.0
PYH2_k127_1407740_5 Permease, YjgP YjgQ family K11720 - - 7.729e-216 676.0
PYH2_k127_1407740_6 Permease, YjgP YjgQ family K07091 - - 7.035e-213 664.0
PYH2_k127_1407740_7 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 503.0
PYH2_k127_1407740_8 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 462.0
PYH2_k127_1407740_9 RNA polymerase K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 382.0
PYH2_k127_1413596_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 1.558e-306 942.0
PYH2_k127_1413596_1 Helicase K03722 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 397.0
PYH2_k127_1413596_2 NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 334.0
PYH2_k127_1413596_3 hydrogenase maturation protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 289.0
PYH2_k127_1421680_0 Ammonium transporter K03320,K06580 - - 3.427e-254 786.0
PYH2_k127_1421680_1 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 4.917e-243 753.0
PYH2_k127_1421680_2 peptidase, U32 K08303 - - 2.849e-237 734.0
PYH2_k127_1421680_3 Predicted periplasmic lipoprotein (DUF2279) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008627 425.0
PYH2_k127_1422738_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000007184 207.0
PYH2_k127_1422738_1 Protein of unknown function (DUF421) - - - 0.000000000000000000000000000000000000000000000000000000003161 205.0
PYH2_k127_1422738_2 Permeases of the major facilitator superfamily - - - 0.000005772 51.0
PYH2_k127_1434929_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0 1135.0
PYH2_k127_1434929_1 Polysulphide reductase, NrfD - - - 9.817e-222 689.0
PYH2_k127_1434929_2 Ni,Fe-hydrogenase I large subunit - - - 4.602e-199 625.0
PYH2_k127_1434929_3 Hydrogenase expression formation protein K03605 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 300.0
PYH2_k127_1434929_4 HupF/HypC family K04653 - - 0.0000000000000000000000000000000000004098 140.0
PYH2_k127_1434929_5 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.000000000000000000000000002242 113.0
PYH2_k127_1439952_0 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004502 484.0
PYH2_k127_1439952_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 464.0
PYH2_k127_1439952_2 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000000002788 126.0
PYH2_k127_1439952_3 PFAM thioesterase superfamily - - - 0.00000000000000103 80.0
PYH2_k127_1492789_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1303.0
PYH2_k127_1492789_1 Belongs to the glycosyl hydrolase 57 family - - - 2.097e-286 882.0
PYH2_k127_1492789_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 3.243e-269 832.0
PYH2_k127_1509865_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1641.0
PYH2_k127_1509865_1 peptidase, U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000001308 218.0
PYH2_k127_1523623_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 1.143e-317 974.0
PYH2_k127_1523623_1 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 492.0
PYH2_k127_1523623_2 PFAM CcdB protein K19163 - - 0.000000000000000000000000000000000002804 139.0
PYH2_k127_1523623_3 Post-segregation antitoxin CcdA K19164 - - 0.00000000000000000000002162 101.0
PYH2_k127_1528547_0 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 563.0
PYH2_k127_1528547_1 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006283 298.0
PYH2_k127_1528547_2 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000003393 183.0
PYH2_k127_1528547_3 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000001045 149.0
PYH2_k127_1528547_4 CBS-domain-containing membrane protein K07168 - - 0.00000000000000000000003621 103.0
PYH2_k127_154130_0 Mg chelatase subunit ChlI K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 423.0
PYH2_k127_154130_1 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 328.0
PYH2_k127_154130_2 Belongs to the P(II) protein family K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000000000007659 219.0
PYH2_k127_154130_3 protein conserved in bacteria K09806 - - 0.00000000000000000000000000000000131 132.0
PYH2_k127_1599510_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 4.533e-284 874.0
PYH2_k127_1599510_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004068 394.0
PYH2_k127_1599510_2 binds to the 23S rRNA K02939 - - 0.000000000000000000000000000000000000000000000000000000000000000903 221.0
PYH2_k127_1599510_3 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.0000000000000000000000000000000000000000000000000000000001858 203.0
PYH2_k127_1599510_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000000000003106 181.0
PYH2_k127_1599510_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0001919 44.0
PYH2_k127_1602193_0 type II secretion system protein E K02454,K02652,K12276 - - 0.0 1106.0
PYH2_k127_1602193_1 Type II and III secretion system protein K02453 - - 5e-324 1001.0
PYH2_k127_1602193_10 ATPase activity, coupled to transmembrane movement of substances - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003461 346.0
PYH2_k127_1602193_11 PFAM Mammalian cell entry related domain protein K02067 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 304.0
PYH2_k127_1602193_13 Protein of unknown function DUF72 - - - 0.0000000000000000000000001682 112.0
PYH2_k127_1602193_2 - - - - 7.767e-261 812.0
PYH2_k127_1602193_3 AAA domain - - - 2.434e-251 781.0
PYH2_k127_1602193_4 Type II secretion system K02653 - - 3.692e-237 736.0
PYH2_k127_1602193_5 Tetratricopeptide repeats - - - 9.077e-195 618.0
PYH2_k127_1602193_6 abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 516.0
PYH2_k127_1602193_7 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 411.0
PYH2_k127_1602193_8 toluene tolerance family protein K07323 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007197 370.0
PYH2_k127_1602193_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 347.0
PYH2_k127_1602997_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1549.0
PYH2_k127_1602997_1 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1222.0
PYH2_k127_1602997_10 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 496.0
PYH2_k127_1602997_11 Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 492.0
PYH2_k127_1602997_12 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003179 376.0
PYH2_k127_1602997_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 327.0
PYH2_k127_1602997_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001163 279.0
PYH2_k127_1602997_15 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001631 246.0
PYH2_k127_1602997_16 ATP synthase I chain K02116 - - 0.0000000000000000000000000000000000000000000000000000003359 196.0
PYH2_k127_1602997_17 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000001824 168.0
PYH2_k127_1602997_18 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000009626 143.0
PYH2_k127_1602997_19 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000001717 121.0
PYH2_k127_1602997_2 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0 998.0
PYH2_k127_1602997_20 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000002958 84.0
PYH2_k127_1602997_21 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000000000002395 79.0
PYH2_k127_1602997_22 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000004739 63.0
PYH2_k127_1602997_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.631e-320 983.0
PYH2_k127_1602997_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.873e-293 900.0
PYH2_k127_1602997_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 3.297e-278 857.0
PYH2_k127_1602997_6 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 8.847e-213 664.0
PYH2_k127_1602997_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006393 558.0
PYH2_k127_1602997_8 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 545.0
PYH2_k127_1602997_9 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 541.0
PYH2_k127_1633394_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1360.0
PYH2_k127_1633394_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 286.0
PYH2_k127_1641372_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.718e-233 729.0
PYH2_k127_1641372_1 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 325.0
PYH2_k127_1641372_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001006 273.0
PYH2_k127_1641372_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.00000000000000000000000000000000001681 143.0
PYH2_k127_1641372_4 ATP synthase delta (OSCP) subunit K02113 - - 0.0000000000000000003849 91.0
PYH2_k127_1641372_5 ATP synthase subunit C K02110 - - 0.0000000000000004994 79.0
PYH2_k127_16509_0 Collagenase K08303 - - 2.687e-238 744.0
PYH2_k127_16509_1 Addiction module toxin RelE StbE family - - - 0.0000000000000000000000000000000000000000000000007824 178.0
PYH2_k127_16509_2 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000000000000000000002291 154.0
PYH2_k127_1685100_0 von Willebrand factor (vWF) type A domain K02448 - - 0.0 1290.0
PYH2_k127_1685100_1 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 523.0
PYH2_k127_1685100_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006456 428.0
PYH2_k127_1685100_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005147 409.0
PYH2_k127_1685100_4 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 396.0
PYH2_k127_1685100_5 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 353.0
PYH2_k127_1685100_6 beta-lactamase K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005823 276.0
PYH2_k127_1685100_7 Response regulator, receiver - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004513 269.0
PYH2_k127_1685100_8 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000006193 228.0
PYH2_k127_171984_0 PFAM EAL domain protein - - - 1.687e-207 651.0
PYH2_k127_171984_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 426.0
PYH2_k127_171984_2 Glycine cleavage system K03567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003071 359.0
PYH2_k127_171984_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001083 264.0
PYH2_k127_1723731_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 551.0
PYH2_k127_1723731_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000003456 203.0
PYH2_k127_1723731_2 - - - - 0.0000000000000000000000000000236 120.0
PYH2_k127_1730421_0 Protein conserved in bacteria - - - 0.0 1146.0
PYH2_k127_1730421_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 580.0
PYH2_k127_1730421_2 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 454.0
PYH2_k127_1730421_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004777 329.0
PYH2_k127_1730421_4 3-5 exonuclease K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002853 257.0
PYH2_k127_1730421_5 Protein of unknown function (DUF1318) K09978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001244 249.0
PYH2_k127_1730421_6 Competence protein ComEA K02237 GO:0005575,GO:0005623,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 - 0.0000000000000000000000000000000000000000014 161.0
PYH2_k127_1730421_7 - - - - 0.000000000000000000000005328 106.0
PYH2_k127_1791199_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 1.059e-226 706.0
PYH2_k127_1791199_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 597.0
PYH2_k127_1791199_2 protein conserved in bacteria K11719 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 372.0
PYH2_k127_1791199_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 334.0
PYH2_k127_1833850_0 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 0.0 999.0
PYH2_k127_1833850_1 PFAM HI0933 family protein K07007 - - 4.798e-203 634.0
PYH2_k127_1833850_2 ubiquinone biosynthetic process from chorismate K03690 GO:0006082,GO:0006732,GO:0006733,GO:0006743,GO:0006744,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0019752,GO:0032150,GO:0042180,GO:0042181,GO:0043436,GO:0043648,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046417,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008295 280.0
PYH2_k127_1883549_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1154.0
PYH2_k127_1883549_1 Glucose inhibited division protein A K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.839e-278 858.0
PYH2_k127_1883549_2 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 8.537e-224 694.0
PYH2_k127_1883549_3 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 372.0
PYH2_k127_1883549_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003821 346.0
PYH2_k127_1883549_5 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000001195 216.0
PYH2_k127_1891427_0 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009482 252.0
PYH2_k127_1891427_1 Glutathione S-transferase, N-terminal domain - - - 0.00000000000000000000000002057 110.0
PYH2_k127_1908891_0 CBS domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 358.0
PYH2_k127_1908891_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 346.0
PYH2_k127_1908891_2 CNP1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 298.0
PYH2_k127_1908891_3 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000003269 232.0
PYH2_k127_1912036_0 Ammonium Transporter Family K03320 - - 1.717e-247 774.0
PYH2_k127_1912036_1 methyltransferase small - - - 1.204e-211 661.0
PYH2_k127_1912036_2 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000000000008388 222.0
PYH2_k127_1912036_3 Protein of unknown function (DUF4080) - - - 0.00001155 48.0
PYH2_k127_1914369_0 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 583.0
PYH2_k127_1914369_1 Pfam Glycosyl transferase family 2 K10012 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003092 319.0
PYH2_k127_1914369_2 Nad-dependent epimerase dehydratase - - - 0.0000000000000000000000000000000000000000000005924 166.0
PYH2_k127_1929665_0 Putative diguanylate phosphodiesterase - - - 0.0 1545.0
PYH2_k127_1929665_1 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1196.0
PYH2_k127_1929665_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 2.861e-238 737.0
PYH2_k127_1929665_3 ABC-type nitrate sulfonate bicarbonate transport K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 574.0
PYH2_k127_1929665_4 TIGRFAM Diguanylate cyclase K13069,K21085 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003223 540.0
PYH2_k127_1929665_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 351.0
PYH2_k127_1929665_6 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.0000000000000000000000000000000000000003262 150.0
PYH2_k127_1934036_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1301.0
PYH2_k127_1934036_1 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 504.0
PYH2_k127_1934036_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 322.0
PYH2_k127_1934036_3 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000000000000000000003632 187.0
PYH2_k127_1944204_0 Diguanylate cyclase K03320 - - 0.0 1288.0
PYH2_k127_1944204_1 GTP-binding protein TypA K06207 - - 0.0 1181.0
PYH2_k127_1944204_2 protein conserved in bacteria K09760 - - 1.175e-263 814.0
PYH2_k127_1944204_3 Belongs to the DEAD box helicase family - GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 - 1.582e-209 662.0
PYH2_k127_1944204_4 PFAM globin K06886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001905 245.0
PYH2_k127_1944204_6 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 0.0000000000000000000000000000001521 123.0
PYH2_k127_1952181_0 PFAM transposase, IS4 family protein - - - 8.719e-244 767.0
PYH2_k127_1952181_1 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.000000000000000004009 84.0
PYH2_k127_1967147_0 Radical SAM K04069 - 1.97.1.4 1.947e-238 741.0
PYH2_k127_1967147_1 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 530.0
PYH2_k127_1967147_2 Dienelactone hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 385.0
PYH2_k127_1967147_3 PFAM AMMECR1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004171 253.0
PYH2_k127_1994376_0 helix_turn_helix, Lux Regulon K03556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001986 384.0
PYH2_k127_2003414_0 Penicillin-binding Protein K05366 - 2.4.1.129,3.4.16.4 0.0 1489.0
PYH2_k127_2003414_1 Putative metallopeptidase domain - - - 6.506e-260 803.0
PYH2_k127_2003414_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 387.0
PYH2_k127_2003414_11 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 355.0
PYH2_k127_2003414_12 PFAM Fimbrial assembly family protein K02663 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 335.0
PYH2_k127_2003414_13 pilus assembly protein PilP K02665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 334.0
PYH2_k127_2003414_14 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 338.0
PYH2_k127_2003414_15 type IV pilus secretin PilQ K02666 - - 0.00000002654 56.0
PYH2_k127_2003414_2 - - - - 4.281e-229 711.0
PYH2_k127_2003414_3 associated with various cellular activities - - - 1.078e-226 702.0
PYH2_k127_2003414_4 Type IV pilus assembly protein PilM K02662 - - 1.042e-222 692.0
PYH2_k127_2003414_5 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 3.911e-214 665.0
PYH2_k127_2003414_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 442.0
PYH2_k127_2003414_7 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 439.0
PYH2_k127_2003414_8 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 397.0
PYH2_k127_2003414_9 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 389.0
PYH2_k127_2007288_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1389.0
PYH2_k127_2007288_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 338.0
PYH2_k127_2007288_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003752 306.0
PYH2_k127_2007288_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008381 250.0
PYH2_k127_2007288_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000003034 87.0
PYH2_k127_2020768_0 response to heat K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 478.0
PYH2_k127_2020768_1 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000000000000000000000000004114 233.0
PYH2_k127_2020768_2 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000000000000000000004327 168.0
PYH2_k127_2020768_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000001773 129.0
PYH2_k127_2020768_4 Involved in arsenical resistance. Thought to form the channel of an arsenite pump K03893 - - 0.000000000000008361 74.0
PYH2_k127_2023049_0 Diguanylate cyclase K13590 - 2.7.7.65 0.0 1064.0
PYH2_k127_2023049_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 548.0
PYH2_k127_2023049_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 499.0
PYH2_k127_2023049_3 PFAM flagellar basal body FlaE domain protein K02390 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 432.0
PYH2_k127_2023049_4 Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly K02386 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 372.0
PYH2_k127_2023049_5 Required for flagellar hook formation. May act as a scaffolding protein K02389 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007406 323.0
PYH2_k127_2023049_6 Belongs to the flagella basal body rod proteins family K02388 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001282 248.0
PYH2_k127_2023049_7 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.000000000000000000000000000000000000000000000000001824 188.0
PYH2_k127_2023049_8 Belongs to the flagella basal body rod proteins family K02391 - - 0.00000000000002684 73.0
PYH2_k127_2065427_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 6.075e-280 861.0
PYH2_k127_2065427_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 366.0
PYH2_k127_2065427_2 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 292.0
PYH2_k127_2097702_0 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 329.0
PYH2_k127_2097702_1 histidine kinase HAMP region domain protein K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 331.0
PYH2_k127_2097702_2 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001166 281.0
PYH2_k127_2097702_3 Aminotransferase class I and II K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000001995 231.0
PYH2_k127_2097702_4 Small Multidrug Resistance protein K03297 - - 0.000000000000000000000000000000000000009116 147.0
PYH2_k127_2099675_0 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 596.0
PYH2_k127_2099675_1 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 492.0
PYH2_k127_2099675_2 chemotaxis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007824 395.0
PYH2_k127_2099675_3 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000002591 250.0
PYH2_k127_2100365_0 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 1.062e-222 691.0
PYH2_k127_2100365_1 Belongs to the BI1 family K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 318.0
PYH2_k127_2105656_0 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 497.0
PYH2_k127_2105656_1 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000001894 268.0
PYH2_k127_2105656_2 - - - - 0.0000000000008661 71.0
PYH2_k127_2142516_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 7.209e-264 813.0
PYH2_k127_2142516_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 1.878e-255 790.0
PYH2_k127_2142516_10 - - - - 0.0000005826 51.0
PYH2_k127_2142516_2 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 7.841e-233 724.0
PYH2_k127_2142516_3 phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008552 538.0
PYH2_k127_2142516_4 phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 503.0
PYH2_k127_2142516_5 dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005471 486.0
PYH2_k127_2142516_6 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 481.0
PYH2_k127_2142516_7 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 422.0
PYH2_k127_2142516_8 FHA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 409.0
PYH2_k127_2142516_9 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000001947 158.0
PYH2_k127_2156362_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1849.0
PYH2_k127_2156362_1 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 9.106e-314 960.0
PYH2_k127_2156362_10 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 546.0
PYH2_k127_2156362_11 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 485.0
PYH2_k127_2156362_12 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 376.0
PYH2_k127_2156362_13 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 366.0
PYH2_k127_2156362_14 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 359.0
PYH2_k127_2156362_15 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 348.0
PYH2_k127_2156362_16 Pfam Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006322 296.0
PYH2_k127_2156362_17 Sh3 type 3 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003294 272.0
PYH2_k127_2156362_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003847 256.0
PYH2_k127_2156362_19 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002217 254.0
PYH2_k127_2156362_2 response regulator K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 2.093e-287 884.0
PYH2_k127_2156362_20 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002546 252.0
PYH2_k127_2156362_21 Thioredoxin domain - - - 0.000000000000000000000000000000001363 130.0
PYH2_k127_2156362_22 transcriptional regulator K09017 - - 0.00000000000000000000000005104 115.0
PYH2_k127_2156362_3 Acts as a magnesium transporter K06213 - - 1.29e-279 864.0
PYH2_k127_2156362_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 2.136e-254 785.0
PYH2_k127_2156362_5 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 1.7e-233 722.0
PYH2_k127_2156362_6 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 3.176e-225 700.0
PYH2_k127_2156362_7 Phosphate transporter K03306 - - 4.034e-202 632.0
PYH2_k127_2156362_8 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 1.156e-197 619.0
PYH2_k127_2156362_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18306 - - 1.376e-195 614.0
PYH2_k127_2179158_0 Metal-dependent hydrolase HDOD - - - 9.087e-203 633.0
PYH2_k127_2179158_1 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 584.0
PYH2_k127_2210709_0 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 404.0
PYH2_k127_2210709_1 Acetyl xylan esterase (AXE1) - - - 0.000000000005295 67.0
PYH2_k127_2221407_0 Cytochrome c-type biogenesis protein K02200 - - 2.337e-223 697.0
PYH2_k127_2221407_1 Cytochrome c-type biogenesis protein CcmF K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 396.0
PYH2_k127_2221407_2 Periplasmic protein thiol K02199 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 358.0
PYH2_k127_2221407_3 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 289.0
PYH2_k127_2223288_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 0.0 1095.0
PYH2_k127_2223288_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 6.45e-253 782.0
PYH2_k127_2223288_2 PFAM type II secretion system protein E K02670 - - 9.506e-219 684.0
PYH2_k127_2223288_3 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 623.0
PYH2_k127_2223288_4 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 549.0
PYH2_k127_2223288_5 Ferrous iron transport protein B K04759 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 308.0
PYH2_k127_2223288_6 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000000000000000000000000000000000005808 202.0
PYH2_k127_2223288_7 PFAM FeoA family protein K04758 - - 0.00000000000002612 86.0
PYH2_k127_2252583_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 3.112e-301 925.0
PYH2_k127_2252583_1 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 557.0
PYH2_k127_2252583_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 536.0
PYH2_k127_2252583_3 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 306.0
PYH2_k127_2252583_4 - - - - 0.0000000000000000000000000000000000000000000000000000005106 194.0
PYH2_k127_2252583_5 p-type atpase - - - 0.00000000000000000000000000000000000000000000000000001276 197.0
PYH2_k127_22544_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 433.0
PYH2_k127_22544_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 422.0
PYH2_k127_22544_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 353.0
PYH2_k127_22544_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 329.0
PYH2_k127_22544_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001644 281.0
PYH2_k127_22544_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000000000000000000002304 213.0
PYH2_k127_22544_6 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000000000000000000000000000000000000000000005522 206.0
PYH2_k127_22544_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000000000004566 181.0
PYH2_k127_22544_8 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000000835 50.0
PYH2_k127_2275201_0 Belongs to the ClpA ClpB family K03694 - - 0.0 1450.0
PYH2_k127_2275201_1 peptidase m48, ste24p - - - 1.866e-277 856.0
PYH2_k127_2275201_10 Protein of unknown function (DUF2892) - - - 0.000000000000000000000000000000001043 131.0
PYH2_k127_2275201_2 PFAM sigma-54 factor interaction domain-containing protein K06714 - - 6.668e-274 846.0
PYH2_k127_2275201_3 pyridine nucleotide-disulphide oxidoreductase K17218 GO:0003674,GO:0003824,GO:0003955,GO:0005488,GO:0005515,GO:0006091,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016491,GO:0016651,GO:0016655,GO:0019646,GO:0022900,GO:0022904,GO:0042802,GO:0044237,GO:0045333,GO:0055114 1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 354.0
PYH2_k127_2275201_4 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 342.0
PYH2_k127_2275201_5 long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 308.0
PYH2_k127_2275201_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 286.0
PYH2_k127_2275201_7 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000589 217.0
PYH2_k127_2275201_8 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.0000000000000000000000000000000000000000000000000000000001647 203.0
PYH2_k127_2275201_9 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000000000005315 149.0
PYH2_k127_2339262_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0 1208.0
PYH2_k127_2339262_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 389.0
PYH2_k127_2385581_0 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 565.0
PYH2_k127_2385581_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 449.0
PYH2_k127_2385581_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 426.0
PYH2_k127_2385581_3 phenylacetate-CoA ligase activity - - - 0.000000000000000000000000000000000000000000000000000002083 198.0
PYH2_k127_2392471_0 Diguanylate cyclase - - - 7.949e-284 888.0
PYH2_k127_2405514_0 type IV pilus secretin PilQ K02666 - - 0.0 1274.0
PYH2_k127_2405514_1 Polysaccharide chain length determinant protein - - - 6.584e-275 851.0
PYH2_k127_2405514_10 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009305 323.0
PYH2_k127_2405514_11 AAA domain K08252,K16692 - 2.7.10.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000769 313.0
PYH2_k127_2405514_2 Protein conserved in bacteria - - - 2.173e-272 845.0
PYH2_k127_2405514_3 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 1.705e-228 709.0
PYH2_k127_2405514_4 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 2.579e-222 692.0
PYH2_k127_2405514_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 8.705e-220 683.0
PYH2_k127_2405514_6 SMART AAA ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 590.0
PYH2_k127_2405514_7 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000641 561.0
PYH2_k127_2405514_8 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002546 492.0
PYH2_k127_2405514_9 polysaccharide export K01991 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 394.0
PYH2_k127_2406037_0 a g-specific adenine glycosylase K03575 - - 2.331e-197 617.0
PYH2_k127_2406037_1 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004787 564.0
PYH2_k127_2406037_2 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000005126 87.0
PYH2_k127_2505807_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 365.0
PYH2_k127_2505807_1 Transferase hexapeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000002137 236.0
PYH2_k127_2505807_2 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000000000000000204 220.0
PYH2_k127_2505807_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000003579 96.0
PYH2_k127_2522936_0 Aspartyl protease K06985 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006867 375.0
PYH2_k127_2522936_1 Tetratricopeptide repeat K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 362.0
PYH2_k127_2589408_0 Alpha amylase, catalytic domain - - - 4.512e-245 764.0
PYH2_k127_2589408_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 483.0
PYH2_k127_2611143_0 Phosphate-selective porin O and P - - - 1.073e-217 683.0
PYH2_k127_2611143_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 312.0
PYH2_k127_2611143_2 DsrE/DsrF-like family K09004 - - 0.0000000000000000000000000000000000000000000000000002874 186.0
PYH2_k127_2621050_0 Protein of unknown function (DUF1569) - - - 0.0009561 48.0
PYH2_k127_2826658_0 Pfam Aminotransferase class I and II K14267 - 2.6.1.17 9.379e-207 643.0
PYH2_k127_2826658_1 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 559.0
PYH2_k127_2826658_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001364 233.0
PYH2_k127_2842905_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.0 1043.0
PYH2_k127_2842905_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 1.59e-231 718.0
PYH2_k127_2842905_2 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009313 548.0
PYH2_k127_2842905_3 SURF1-like protein K14998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 415.0
PYH2_k127_2842905_4 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006085 338.0
PYH2_k127_2842905_5 cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001022 247.0
PYH2_k127_2842905_7 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000004569 104.0
PYH2_k127_2867706_0 Ferrous iron transport protein B K04759 - - 1.152e-290 894.0
PYH2_k127_2867706_1 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 511.0
PYH2_k127_2867706_2 methyltransferase K03437 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 414.0
PYH2_k127_2873220_0 PFAM PhoH family protein K07175 - - 4.33e-304 933.0
PYH2_k127_2873220_1 major facilitator superfamily - - - 3.246e-247 766.0
PYH2_k127_2873220_10 - - - - 0.00000000000000000000000000000000000000000000000000002793 190.0
PYH2_k127_2873220_2 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004619 557.0
PYH2_k127_2873220_3 COG1512 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 428.0
PYH2_k127_2873220_4 uracil-DNA glycosylase K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 378.0
PYH2_k127_2873220_5 LemA Family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004197 368.0
PYH2_k127_2873220_6 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 294.0
PYH2_k127_2873220_7 Peptidase M22 glycoprotease K14742 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 291.0
PYH2_k127_2873220_8 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 291.0
PYH2_k127_2873220_9 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003458 252.0
PYH2_k127_2891443_0 EAL domain - - - 0.0 1246.0
PYH2_k127_2891443_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 4.247e-295 907.0
PYH2_k127_2891443_10 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000000000002807 158.0
PYH2_k127_2891443_2 histidyl-tRNA synthetase K01892 - 6.1.1.21 1.483e-254 788.0
PYH2_k127_2891443_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 2.066e-231 719.0
PYH2_k127_2891443_4 - - - - 1.37e-225 702.0
PYH2_k127_2891443_5 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 7.334e-221 686.0
PYH2_k127_2891443_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 2.279e-196 614.0
PYH2_k127_2891443_7 Type IV pilus biogenesis stability protein PilW K02656 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 466.0
PYH2_k127_2891443_8 Transcriptional regulator K15539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 448.0
PYH2_k127_2891443_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 391.0
PYH2_k127_2902849_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 9.518e-238 735.0
PYH2_k127_2902849_1 Major facilitator Superfamily K05820 - - 5.862e-232 721.0
PYH2_k127_2902849_2 DNA ligase K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 503.0
PYH2_k127_2902849_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008445 261.0
PYH2_k127_2902849_4 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000000000000000000000000000000000000001194 184.0
PYH2_k127_2902849_5 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000000000000000000000002501 173.0
PYH2_k127_2902849_6 Protein of unknown function (DUF3018) - - - 0.00000000000000000000000000000000001151 136.0
PYH2_k127_2902849_7 PEP-CTERM motif - - - 0.000000000000000000000000000000008954 132.0
PYH2_k127_2985010_0 type II and III secretion system protein K02453,K12282 - - 0.0 1079.0
PYH2_k127_2985010_1 type II secretion system protein E K02454,K02652,K12276 - - 0.0 1067.0
PYH2_k127_2985010_10 carbon utilization K12280 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 361.0
PYH2_k127_2985010_11 general secretion pathway protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 331.0
PYH2_k127_2985010_12 PFAM Fimbrial assembly family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 331.0
PYH2_k127_2985010_13 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 295.0
PYH2_k127_2985010_14 Prokaryotic N-terminal methylation motif K10924 - - 0.00000000000000000000000000000000000000000000000000000000000000000005407 235.0
PYH2_k127_2985010_15 - K12281 - - 0.00000000000000000000000000000000000000000000000007156 180.0
PYH2_k127_2985010_16 Pilus assembly protein PilX K12286 - - 0.000000000000000000000000000000000000000000000006914 177.0
PYH2_k127_2985010_17 Tfp pilus assembly protein FimT K10926 - - 0.00000000000000000000000000000000000000000000003957 173.0
PYH2_k127_2985010_18 type IV pilus modification protein PilV K10927 - - 0.00000000000000000000000000000000000000003515 156.0
PYH2_k127_2985010_19 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000000000000000000000007146 123.0
PYH2_k127_2985010_2 Type II secretion system K02455,K12278 - - 3.785e-232 722.0
PYH2_k127_2985010_20 - - - - 0.00000000255 61.0
PYH2_k127_2985010_3 Tetratricopeptide repeat K12284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 557.0
PYH2_k127_2985010_4 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004151 539.0
PYH2_k127_2985010_5 AAA domain K02450,K12283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 535.0
PYH2_k127_2985010_6 PFAM Fimbrial assembly family protein K12279 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 516.0
PYH2_k127_2985010_7 Prokaryotic N-terminal methylation motif K12285 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 457.0
PYH2_k127_2985010_8 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 439.0
PYH2_k127_2985010_9 Conserved repeat domain K12287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 416.0
PYH2_k127_3023110_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 3.252e-277 854.0
PYH2_k127_3023110_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 9.628e-214 666.0
PYH2_k127_3023110_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001444 467.0
PYH2_k127_3023110_3 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 425.0
PYH2_k127_3023110_4 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 408.0
PYH2_k127_3023110_5 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 296.0
PYH2_k127_3023110_6 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000001091 147.0
PYH2_k127_3027154_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 2.863e-304 946.0
PYH2_k127_3030948_0 Isochorismate synthase K01851,K02361,K02552 - 5.4.4.2 2.504e-256 794.0
PYH2_k127_3030948_1 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.000000000000000000000000000000000000000004297 155.0
PYH2_k127_3033157_0 COG NOG04879 non supervised orthologous group K05340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 409.0
PYH2_k127_3033157_1 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000004715 158.0
PYH2_k127_3033157_2 PQQ-like domain - - - 0.000000006023 57.0
PYH2_k127_3077455_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.0 1034.0
PYH2_k127_3077455_1 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 509.0
PYH2_k127_3077455_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 321.0
PYH2_k127_3077455_3 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.0000000000000000000000000000000000000000000000000000000000000181 216.0
PYH2_k127_3077455_4 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000000000000000000000000000001286 195.0
PYH2_k127_3077455_5 YqjK-like protein - - - 0.0000000000002048 74.0
PYH2_k127_3101954_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 3.419e-263 812.0
PYH2_k127_3101954_1 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 6.821e-203 636.0
PYH2_k127_3101954_2 Phosphotransferase K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 604.0
PYH2_k127_3101954_3 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 570.0
PYH2_k127_3101954_4 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 444.0
PYH2_k127_3119860_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1729.0
PYH2_k127_3119960_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 2.057e-283 874.0
PYH2_k127_3119960_1 Metallo-beta-lactamase superfamily - - - 3.579e-213 665.0
PYH2_k127_3119960_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000951 510.0
PYH2_k127_3119960_3 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 430.0
PYH2_k127_3119960_4 Psort location CytoplasmicMembrane, score 10.00 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 429.0
PYH2_k127_3119960_5 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 294.0
PYH2_k127_3119960_6 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000000000006024 198.0
PYH2_k127_3119960_7 PFAM deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000001469 174.0
PYH2_k127_3119960_8 ABC transporter K02013 - 3.6.3.34 0.000000001039 59.0
PYH2_k127_3120131_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 2.046e-285 876.0
PYH2_k127_3120131_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 3.187e-285 876.0
PYH2_k127_3120131_2 NADH-quinone oxidoreductase K00336 - 1.6.5.3 1.897e-216 676.0
PYH2_k127_3120131_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 302.0
PYH2_k127_3120131_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000001107 88.0
PYH2_k127_3122554_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003578 391.0
PYH2_k127_3122554_1 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000117 234.0
PYH2_k127_3124127_0 4Fe-4S binding domain - - - 7.383e-200 625.0
PYH2_k127_3124127_1 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 523.0
PYH2_k127_3124127_2 Cytochrome c oxidase subunit III K02164,K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005485 371.0
PYH2_k127_3124127_3 Prokaryotic Cytochrome C oxidase subunit IV - - - 0.0000000000000000000000000000000000000000000000001287 177.0
PYH2_k127_3124127_4 - - - - 0.0000000000000000000000000000002124 127.0
PYH2_k127_3124127_5 Nitric oxide reductase K04561 - 1.7.2.5 0.0000000000000000000003115 95.0
PYH2_k127_3130550_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007227 583.0
PYH2_k127_3148500_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1206.0
PYH2_k127_3148500_1 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1088.0
PYH2_k127_3148500_10 rna-binding protein K07574 - - 0.00000000000000000000000000000000000000000000000000001629 188.0
PYH2_k127_3148500_2 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 6.667e-287 882.0
PYH2_k127_3148500_3 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000191 582.0
PYH2_k127_3148500_4 phosphate transport system permease K02038 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007722 538.0
PYH2_k127_3148500_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008019 516.0
PYH2_k127_3148500_6 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000661 439.0
PYH2_k127_3148500_7 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 402.0
PYH2_k127_3148500_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 291.0
PYH2_k127_3148500_9 Domain of unknown function (DUF4149) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 289.0
PYH2_k127_3166624_0 flagellar hook-associated protein K02396 - - 1.022e-228 726.0
PYH2_k127_3166624_1 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 1.199e-205 644.0
PYH2_k127_3166624_2 Flagellar rod assembly protein muramidase FlgJ K02395 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 509.0
PYH2_k127_3166624_3 flagellar basal-body rod protein K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 479.0
PYH2_k127_3166624_4 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003901 438.0
PYH2_k127_3166624_5 Belongs to the flagella basal body rod proteins family K02391 - - 0.000000000008253 65.0
PYH2_k127_3192889_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 535.0
PYH2_k127_3192889_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 482.0
PYH2_k127_3192889_2 UBA THIF-type NAD FAD binding protein K22132 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008967 469.0
PYH2_k127_3192889_3 PFAM TatD-related deoxyribonuclease K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 467.0
PYH2_k127_3203447_0 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 6.434e-294 905.0
PYH2_k127_3203447_1 PFAM RIO-like kinase K07178 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009103 537.0
PYH2_k127_3203447_2 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 436.0
PYH2_k127_3203447_3 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000003807 228.0
PYH2_k127_3203447_4 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000005936 210.0
PYH2_k127_3203447_5 Sterol-binding domain protein - - - 0.000000000000000000000000000000000000000000005736 164.0
PYH2_k127_3203447_6 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000003971 74.0
PYH2_k127_3225383_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0 1046.0
PYH2_k127_3225383_1 Belongs to the GcvT family K06980 - - 3.65e-202 631.0
PYH2_k127_3225383_2 RNA-metabolising metallo-beta-lactamase K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 574.0
PYH2_k127_3225383_3 negative regulator of sigma E activity K03598 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 543.0
PYH2_k127_3225383_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 384.0
PYH2_k127_3225383_5 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003824 357.0
PYH2_k127_3225383_6 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001605 264.0
PYH2_k127_3225383_7 Anti sigma-E protein RseA K03597 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001201 256.0
PYH2_k127_3225383_8 Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins K19168 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001673 249.0
PYH2_k127_3227396_0 Isocitrate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 5.138e-261 805.0
PYH2_k127_3227396_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 596.0
PYH2_k127_3227396_2 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 515.0
PYH2_k127_3227396_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007508 329.0
PYH2_k127_3227396_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000679 269.0
PYH2_k127_3227396_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000002532 217.0
PYH2_k127_3227396_7 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000001222 59.0
PYH2_k127_3227396_8 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000007043 57.0
PYH2_k127_3256314_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1334.0
PYH2_k127_3256314_1 Inositol-1-monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 502.0
PYH2_k127_3256314_2 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 449.0
PYH2_k127_3256314_3 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 379.0
PYH2_k127_3262007_0 Sodium:solute symporter family K14393 - - 0.0 1171.0
PYH2_k127_3262007_1 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 9.006e-252 781.0
PYH2_k127_3262007_2 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000645 422.0
PYH2_k127_3262007_3 Domain of unknown function (DUF4212) - - - 0.0000000000000000000000000000000000000000001166 160.0
PYH2_k127_3262007_4 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000008726 144.0
PYH2_k127_3262007_5 - - - - 0.0000000000000000000007966 95.0
PYH2_k127_3268858_0 Outer membrane protein beta-barrel family - - - 4.433e-255 805.0
PYH2_k127_3268858_1 TonB dependent receptor K02014 - - 2.114e-242 760.0
PYH2_k127_3268858_2 PFAM sigma-54 factor interaction domain-containing protein - - - 4.613e-194 607.0
PYH2_k127_3268858_3 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 564.0
PYH2_k127_3268858_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005215 464.0
PYH2_k127_3268858_5 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 374.0
PYH2_k127_3268858_6 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002746 280.0
PYH2_k127_3268858_7 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001915 263.0
PYH2_k127_3268858_8 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.000000000000000000000000000000000000000000000000005042 181.0
PYH2_k127_3302704_0 PFAM phospholipid glycerol acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 336.0
PYH2_k127_3303456_0 Major Facilitator - - - 2.607e-280 864.0
PYH2_k127_3303456_1 Flagellar assembly protein T, middle domain - - - 7.592e-227 712.0
PYH2_k127_3303456_2 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004153 484.0
PYH2_k127_3303456_3 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 404.0
PYH2_k127_3303456_4 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003729 379.0
PYH2_k127_3303456_5 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000004911 59.0
PYH2_k127_3308552_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K02567 - - 0.0 1534.0
PYH2_k127_3308552_1 CRP FNR family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 428.0
PYH2_k127_3308552_2 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006731 242.0
PYH2_k127_3308552_3 cytochrome - - - 0.000000000000000000000000000000000000000000000000000000000001155 209.0
PYH2_k127_3308552_4 Ferredoxin-type protein NapF K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000001382 184.0
PYH2_k127_3308552_5 Pfam cytochrome c K17230 - - 0.0000000000000000000000000000000000000000002255 160.0
PYH2_k127_3338607_0 Nitrous-oxide reductase is part of a bacterial respiratory system which is activated under anaerobic conditions in the presence of nitrate or nitrous oxide K00376 - 1.7.2.4 0.0 1470.0
PYH2_k127_3338607_1 Periplasmic copper-binding K07218 - - 3.005e-203 640.0
PYH2_k127_3338607_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 463.0
PYH2_k127_3338607_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 416.0
PYH2_k127_3338607_12 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 398.0
PYH2_k127_3338607_13 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 286.0
PYH2_k127_3338607_14 NosL - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002226 274.0
PYH2_k127_3338607_15 Cytochrome C oxidase, cbb3-type, subunit III K08738 - - 0.00000000000000000000000000000000000000000000000004098 179.0
PYH2_k127_3338607_2 4Fe-4S binding domain K02574 - - 1.501e-198 621.0
PYH2_k127_3338607_3 4Fe-4S dicluster domain K02573 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 554.0
PYH2_k127_3338607_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003133 544.0
PYH2_k127_3338607_5 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 539.0
PYH2_k127_3338607_6 mandelate racemase muconate lactonizing K01856,K01860,K02549,K19802,K21617,K21624 - 4.2.1.113,4.2.1.171,5.1.1.20,5.1.1.22,5.5.1.1,5.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 533.0
PYH2_k127_3338607_7 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 528.0
PYH2_k127_3338607_8 ABC-type transport system involved in multi-copper enzyme maturation permease component K01992,K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 524.0
PYH2_k127_3338607_9 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009075 492.0
PYH2_k127_3357903_0 Diguanylate cyclase - - - 1.399e-307 953.0
PYH2_k127_3357903_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000001017 158.0
PYH2_k127_3458657_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 0.0 1137.0
PYH2_k127_3458657_1 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004684 496.0
PYH2_k127_3458657_2 Fructosamine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 399.0
PYH2_k127_3458657_3 sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000213 273.0
PYH2_k127_3458657_4 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000002501 221.0
PYH2_k127_3458657_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000002812 218.0
PYH2_k127_3458657_6 PFAM Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000000000000000000001979 195.0
PYH2_k127_3458657_7 Putative motility protein - - - 0.0003365 45.0
PYH2_k127_3477265_0 NADH ubiquinone plastoquinone (Complex I) - - - 0.0 1077.0
PYH2_k127_3477265_1 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 2.23e-303 932.0
PYH2_k127_3477265_2 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 542.0
PYH2_k127_3477265_3 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 374.0
PYH2_k127_3477265_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000001134 135.0
PYH2_k127_3477265_5 Peptidase family S51 - - - 0.00000000002643 64.0
PYH2_k127_3500075_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1456.0
PYH2_k127_3500075_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 595.0
PYH2_k127_3500075_2 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 445.0
PYH2_k127_3500075_3 - - - - 0.000000000000000000000000000000132 128.0
PYH2_k127_3500075_4 addiction module antidote protein - - - 0.0000000000008448 68.0
PYH2_k127_3512976_0 Domain of unknown function DUF87 K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 440.0
PYH2_k127_3512976_1 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 405.0
PYH2_k127_3512976_2 YaeQ - - - 0.00000000001654 64.0
PYH2_k127_355303_0 HI0933 family K07007 - - 3.215e-235 728.0
PYH2_k127_355303_1 Helix-turn-helix type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004217 585.0
PYH2_k127_355303_2 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 424.0
PYH2_k127_355303_3 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 360.0
PYH2_k127_355303_4 hydrolases of HD superfamily K06952 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005891 343.0
PYH2_k127_355303_5 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 318.0
PYH2_k127_355303_6 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009733 254.0
PYH2_k127_355303_7 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000000000002732 168.0
PYH2_k127_355303_8 - - - - 0.00000000000000000000000000000000000000008173 151.0
PYH2_k127_3563871_0 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005729 474.0
PYH2_k127_3563871_1 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 461.0
PYH2_k127_3563871_2 PFAM Ankyrin K10799 - 2.4.2.30 0.00000000000000000000000000000000000000000000000000000000000000000003627 250.0
PYH2_k127_3563871_3 DnaJ-class molecular chaperone - - - 0.0000000000000135 73.0
PYH2_k127_3571033_0 COG2202 FOG PAS PAC domain K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 540.0
PYH2_k127_3571033_1 PFAM NnrS family protein K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000345 276.0
PYH2_k127_3571033_2 Transcriptional regulator K13771 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002917 248.0
PYH2_k127_3571033_3 von Willebrand factor, type A K02448 - - 0.00000000000000000000000000000000000000000000000000000000003466 205.0
PYH2_k127_3571033_4 SlyX K03745 - - 0.00000000000000000000000000001031 120.0
PYH2_k127_3602843_0 hmm pf01609 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 342.0
PYH2_k127_3602843_1 hmm pf01609 - - - 0.000000000000002318 80.0
PYH2_k127_3606098_0 chemotaxis K03406 - - 1.18e-315 974.0
PYH2_k127_3606098_1 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005705 423.0
PYH2_k127_3606098_2 glycosyl - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 394.0
PYH2_k127_3606098_3 Thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 391.0
PYH2_k127_3606098_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 372.0
PYH2_k127_3606098_5 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000003495 239.0
PYH2_k127_3624374_0 serine threonine protein kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000002257 227.0
PYH2_k127_3624374_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000004325 130.0
PYH2_k127_3636319_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 4.474e-263 812.0
PYH2_k127_3636319_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 2.853e-260 803.0
PYH2_k127_3636319_10 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000000000000000000007535 216.0
PYH2_k127_3636319_11 toluene tolerance family protein K07323 - - 0.00000000000000000000000000000000000000000000000000001622 189.0
PYH2_k127_3636319_12 Belongs to the BolA IbaG family - - - 0.00000000000000000000000000000000000000000004322 161.0
PYH2_k127_3636319_13 response to antibiotic K07122 - - 0.00000000000000000000000000000000000000003049 156.0
PYH2_k127_3636319_14 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000007088 79.0
PYH2_k127_3636319_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 1.996e-210 656.0
PYH2_k127_3636319_3 abc transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003305 569.0
PYH2_k127_3636319_4 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004955 499.0
PYH2_k127_3636319_5 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 492.0
PYH2_k127_3636319_6 Transport permease protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 467.0
PYH2_k127_3636319_7 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 425.0
PYH2_k127_3636319_8 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008913 415.0
PYH2_k127_3636319_9 imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 390.0
PYH2_k127_3675934_0 Peptidase family U32 C-terminal domain K08303 - - 1.948e-264 817.0
PYH2_k127_3675934_1 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 454.0
PYH2_k127_3675934_2 Domain of unknown function (DUF386) - - - 0.00000000000000000000000000000000000000000000000000000000000000001889 228.0
PYH2_k127_3675934_3 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0000097,GO:0000166,GO:0001666,GO:0002376,GO:0002437,GO:0002439,GO:0002544,GO:0003674,GO:0003824,GO:0004013,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006152,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0006950,GO:0006952,GO:0006954,GO:0006955,GO:0007584,GO:0007610,GO:0007622,GO:0007623,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009164,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016053,GO:0016054,GO:0016787,GO:0016801,GO:0016802,GO:0017076,GO:0017144,GO:0019439,GO:0019510,GO:0019752,GO:0030554,GO:0031667,GO:0033353,GO:0034641,GO:0034655,GO:0034656,GO:0036094,GO:0036293,GO:0042219,GO:0042221,GO:0042278,GO:0042454,GO:0042745,GO:0042802,GO:0042995,GO:0043005,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046130,GO:0046394,GO:0046395,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0046700,GO:0048037,GO:0048511,GO:0048512,GO:0050662,GO:0050667,GO:0050896,GO:0051186,GO:0051187,GO:0051287,GO:0055086,GO:0070482,GO:0071268,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097458,GO:0098604,GO:0120025,GO:1901135,GO:1901136,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1901657,GO:1901658 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000684 195.0
PYH2_k127_3675934_4 membrane K08972 - - 0.0000000000000000000000000000000000002771 145.0
PYH2_k127_3721277_0 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 550.0
PYH2_k127_3721277_1 Protein of unknown function, DUF599 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 426.0
PYH2_k127_3721277_2 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 425.0
PYH2_k127_3721277_3 Domain of unknown function (DUF4202) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 393.0
PYH2_k127_3721277_4 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 293.0
PYH2_k127_3721277_5 - - - - 0.000000000000000000000000000000000000000000000005685 175.0
PYH2_k127_3757122_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 2.502e-268 831.0
PYH2_k127_3757122_1 - - - - 8.041e-227 704.0
PYH2_k127_3757122_10 PTS IIA-like nitrogen-regulatory protein PtsN K02806 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004515 254.0
PYH2_k127_3757122_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008402 244.0
PYH2_k127_3757122_12 NusG domain II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009395 237.0
PYH2_k127_3757122_13 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000000000000000000000000000009142 216.0
PYH2_k127_3757122_14 - - - - 0.000000000000000000000000000000000000000000000000002673 183.0
PYH2_k127_3757122_17 Hemerythrin HHE cation binding domain K07216 - - 0.000000003116 64.0
PYH2_k127_3757122_2 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 581.0
PYH2_k127_3757122_3 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 494.0
PYH2_k127_3757122_4 ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 460.0
PYH2_k127_3757122_5 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 395.0
PYH2_k127_3757122_6 Pfam:Pyridox_oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009707 349.0
PYH2_k127_3757122_7 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 341.0
PYH2_k127_3757122_8 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 301.0
PYH2_k127_3768052_0 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 1.039e-207 648.0
PYH2_k127_3768052_1 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 441.0
PYH2_k127_3768052_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002046 271.0
PYH2_k127_377878_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 1.483e-214 667.0
PYH2_k127_377878_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 394.0
PYH2_k127_377878_2 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003585 301.0
PYH2_k127_377878_3 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008654 273.0
PYH2_k127_377878_4 Belongs to the CinA family K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000005198 264.0
PYH2_k127_377878_5 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000000000000005742 214.0
PYH2_k127_377878_6 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000000000000000008216 210.0
PYH2_k127_377878_7 - - - - 0.00000000000000000000000000000000000000000000000000000000002585 206.0
PYH2_k127_3812904_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 596.0
PYH2_k127_3812904_1 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 425.0
PYH2_k127_3812904_2 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 385.0
PYH2_k127_3837700_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 435.0
PYH2_k127_3837700_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 338.0
PYH2_k127_3837700_2 Protein of unknown function (DUF3293) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007568 238.0
PYH2_k127_3837700_3 catalase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.0000000000000000000000000000000000000000000000000001034 186.0
PYH2_k127_3837700_4 PLD-like domain - - - 0.00000000000000000000000000000000000000000000007019 173.0
PYH2_k127_3849345_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1560.0
PYH2_k127_3849345_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1499.0
PYH2_k127_3849345_10 Belongs to the BolA IbaG family K05527 - - 0.00000000000000000000000000000000000000000000001923 171.0
PYH2_k127_3849345_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 8.249e-263 811.0
PYH2_k127_3849345_3 SMART phosphoesterase PHP domain protein K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 535.0
PYH2_k127_3849345_4 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 497.0
PYH2_k127_3849345_5 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005574 421.0
PYH2_k127_3849345_6 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 395.0
PYH2_k127_3849345_7 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 389.0
PYH2_k127_3849345_8 response regulator K20977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 309.0
PYH2_k127_3849345_9 PFAM YCII-related K09780 - - 0.00000000000000000000000000000000000000000000000000396 182.0
PYH2_k127_3897026_0 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 1.943e-261 807.0
PYH2_k127_3897026_1 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 529.0
PYH2_k127_3897026_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 462.0
PYH2_k127_3897026_3 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009913 434.0
PYH2_k127_3897026_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 388.0
PYH2_k127_3897026_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008682 356.0
PYH2_k127_3936495_0 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.0 1600.0
PYH2_k127_3936495_1 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0 1025.0
PYH2_k127_3936495_2 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K16898 - 3.6.4.12 3.28e-320 984.0
PYH2_k127_3936495_3 Peptidase family M48 - - - 5.051e-288 887.0
PYH2_k127_3936495_4 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.654e-269 829.0
PYH2_k127_3936495_5 ADP-glyceromanno-heptose 6-epimerase activity K00091,K01710 - 1.1.1.219,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 353.0
PYH2_k127_3936495_6 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000000000000000000003232 226.0
PYH2_k127_3936495_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000004331 204.0
PYH2_k127_3936495_8 Binds the 23S rRNA K02909 - - 0.00000000000000000000000000000000000005201 142.0
PYH2_k127_3937981_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1517.0
PYH2_k127_3937981_1 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 4.07e-272 845.0
PYH2_k127_3937981_10 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000000000000000000000000005382 205.0
PYH2_k127_3937981_11 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000000000000003242 167.0
PYH2_k127_3937981_12 PQ loop repeat K15383 - - 0.000000000000000000000000000000000000000006647 156.0
PYH2_k127_3937981_13 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000005912 117.0
PYH2_k127_3937981_14 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000006427 98.0
PYH2_k127_3937981_16 - - - - 0.0008535 47.0
PYH2_k127_3937981_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 5.52e-226 701.0
PYH2_k127_3937981_3 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 606.0
PYH2_k127_3937981_4 PFAM sodium calcium exchanger membrane region K07301 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 598.0
PYH2_k127_3937981_5 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 559.0
PYH2_k127_3937981_6 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 494.0
PYH2_k127_3937981_7 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009451 416.0
PYH2_k127_3937981_8 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 374.0
PYH2_k127_3937981_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 354.0
PYH2_k127_3961319_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic domain K01886 - 6.1.1.18 9.126e-210 653.0
PYH2_k127_3961319_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000002711 170.0
PYH2_k127_3961319_2 Universal stress protein - - - 0.0000000000000000000000000001135 120.0
PYH2_k127_3967328_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 465.0
PYH2_k127_3985833_0 Extracellular solute-binding protein - - - 0.0 1077.0
PYH2_k127_3985833_1 alcohol dehydrogenase K00001 - 1.1.1.1 1.812e-239 742.0
PYH2_k127_3985833_2 Cytochrome c bacterial - - - 4.002e-196 614.0
PYH2_k127_3985833_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002598 509.0
PYH2_k127_3985833_4 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 334.0
PYH2_k127_3999783_0 EAL domain - - - 0.0 1072.0
PYH2_k127_3999783_1 Response regulator receiver - - - 1.613e-292 905.0
PYH2_k127_3999783_10 PFAM RNA-binding S4 domain protein K04762 - - 0.0000000000000000000000000000000000000000000000000000000000000003724 221.0
PYH2_k127_3999783_11 - - - - 0.00000000000000000000000000000000000000000000000000001884 188.0
PYH2_k127_3999783_12 - - - - 0.0000000000000000000000000000000000003458 141.0
PYH2_k127_3999783_13 - - - - 0.00000000000000000000000000000000242 130.0
PYH2_k127_3999783_14 chain release factor K15034 - - 0.000000000000000000000000001144 112.0
PYH2_k127_3999783_15 Psort location CytoplasmicMembrane, score - - - 0.00002085 55.0
PYH2_k127_3999783_2 PFAM EAL domain protein - - - 1.932e-242 753.0
PYH2_k127_3999783_3 Nadh flavin oxidoreductase nadh oxidase K10680 GO:0000003,GO:0000302,GO:0001101,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006950,GO:0006979,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009605,GO:0009607,GO:0009620,GO:0009694,GO:0009695,GO:0009791,GO:0009908,GO:0009987,GO:0010035,GO:0010193,GO:0010817,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016629,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0042221,GO:0042445,GO:0042446,GO:0042493,GO:0042579,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046677,GO:0048367,GO:0048437,GO:0048438,GO:0048443,GO:0048466,GO:0048608,GO:0048731,GO:0048827,GO:0048856,GO:0050896,GO:0051704,GO:0051707,GO:0055114,GO:0061458,GO:0065007,GO:0065008,GO:0071704,GO:0072330,GO:0090567,GO:0099402,GO:1901576,GO:1901700 - 1.735e-224 698.0
PYH2_k127_3999783_4 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 566.0
PYH2_k127_3999783_5 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 542.0
PYH2_k127_3999783_6 CobW/HypB/UreG, nucleotide-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 467.0
PYH2_k127_3999783_7 Pfam Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004328 409.0
PYH2_k127_3999783_8 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008477 361.0
PYH2_k127_3999783_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008164 293.0
PYH2_k127_401334_0 Mota tolq exbb proton channel K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007853 401.0
PYH2_k127_401334_1 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000785 265.0
PYH2_k127_401334_2 Pfam Biopolymer transport protein ExbD TolR K03559,K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001012 250.0
PYH2_k127_401334_3 MltA specific insert domain K08304 - - 0.00000000000000000000000000000000000000007741 152.0
PYH2_k127_401334_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000003371 74.0
PYH2_k127_4013733_0 diguanylate cyclase - - - 0.0 1133.0
PYH2_k127_4013733_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 6.982e-237 735.0
PYH2_k127_4013733_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000000000000000000000000000004507 213.0
PYH2_k127_4013733_11 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.0000000000000000000000000000000000000000000000000000003554 196.0
PYH2_k127_4013733_12 Histidine triad (Hit) protein K02503 - - 0.0000000000000000000000000000000000000000000000000000008327 193.0
PYH2_k127_4013733_13 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000000000000000004395 140.0
PYH2_k127_4013733_14 - - - - 0.000001395 51.0
PYH2_k127_4013733_15 - - - - 0.00009728 45.0
PYH2_k127_4013733_2 Belongs to the peptidase S1C family K04691,K04772 - - 7.447e-223 694.0
PYH2_k127_4013733_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 484.0
PYH2_k127_4013733_4 dinuclear metal center protein, YbgI - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 446.0
PYH2_k127_4013733_5 Cytochrome C1 K00413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 428.0
PYH2_k127_4013733_6 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 402.0
PYH2_k127_4013733_7 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003962 327.0
PYH2_k127_4013733_8 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003976 267.0
PYH2_k127_4013733_9 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004182 248.0
PYH2_k127_4015510_0 Belongs to the peptidase S16 family - - - 0.0 1204.0
PYH2_k127_4015510_1 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 6.673e-221 689.0
PYH2_k127_4015510_10 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 324.0
PYH2_k127_4015510_11 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 299.0
PYH2_k127_4015510_12 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008034 282.0
PYH2_k127_4015510_13 PFAM regulatory protein, MarR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001708 269.0
PYH2_k127_4015510_14 Bacterial regulatory protein, arsR family K03892 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001409 242.0
PYH2_k127_4015510_15 Signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000003347 205.0
PYH2_k127_4015510_16 ANTAR K22010 - - 0.000000000000000000000000000000000000000000000000000005739 197.0
PYH2_k127_4015510_17 SMART zinc finger, CDGSH-type domain protein - - - 0.00000000000000000000000000000000000000000000000002515 180.0
PYH2_k127_4015510_18 - - - - 0.0000000000000000000000000000000000000000000000001451 177.0
PYH2_k127_4015510_19 GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000001475 165.0
PYH2_k127_4015510_2 Transcriptional regulator K04761 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 566.0
PYH2_k127_4015510_20 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000128 156.0
PYH2_k127_4015510_22 tigrfam pas - - - 0.00000000000000000000000000000000002588 145.0
PYH2_k127_4015510_23 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000005425 129.0
PYH2_k127_4015510_24 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000005378 124.0
PYH2_k127_4015510_25 Thioredoxin domain - - - 0.00000000000000000266 84.0
PYH2_k127_4015510_3 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 565.0
PYH2_k127_4015510_4 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 516.0
PYH2_k127_4015510_5 Methyltransferase type 11 K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000038 456.0
PYH2_k127_4015510_6 Cytochrome b561 K12262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009491 365.0
PYH2_k127_4015510_7 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005842 354.0
PYH2_k127_4015510_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 342.0
PYH2_k127_4015510_9 Histidine kinase K07675,K20263 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006888 337.0
PYH2_k127_4023457_0 ribonuclease II K01147 - 3.1.13.1 0.0 1185.0
PYH2_k127_4023457_1 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 5.573e-285 878.0
PYH2_k127_4023457_10 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 315.0
PYH2_k127_4023457_11 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000003367 241.0
PYH2_k127_4023457_12 Diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000000000000000000000000000000001502 221.0
PYH2_k127_4023457_13 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000002542 154.0
PYH2_k127_4023457_14 Diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000506 149.0
PYH2_k127_4023457_15 sulfur carrier activity K04085,K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.000000000000000000000002801 104.0
PYH2_k127_4023457_2 dihydroorotase K01465 - 3.5.2.3 1.239e-237 736.0
PYH2_k127_4023457_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 601.0
PYH2_k127_4023457_4 Belongs to the glucose-6-phosphate 1-epimerase family K01792 - 5.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 568.0
PYH2_k127_4023457_5 TIGRFAM TonB family protein K03832 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 519.0
PYH2_k127_4023457_6 PFAM Metal-dependent hydrolase HDOD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 519.0
PYH2_k127_4023457_7 sulfur carrier activity K04085,K07112 GO:0008150,GO:0009987,GO:0019725,GO:0042592,GO:0048878,GO:0055082,GO:0065007,GO:0065008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 467.0
PYH2_k127_4023457_8 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 366.0
PYH2_k127_4023457_9 esterase K07000 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 346.0
PYH2_k127_4032977_0 AMP-binding enzyme C-terminal domain K00666 - - 2.172e-273 852.0
PYH2_k127_4032977_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 581.0
PYH2_k127_4032977_10 Hemerythrin HHE cation binding domain K07216 - - 0.0000000000000000000000000000000000000000004323 162.0
PYH2_k127_4032977_11 THUMP - - - 0.0000000000000000000000000000000000006604 146.0
PYH2_k127_4032977_12 - - - - 0.000000000000000000000000000000000004179 143.0
PYH2_k127_4032977_13 PFAM ThiJ PfpI K05520 - 3.5.1.124 0.00001884 48.0
PYH2_k127_4032977_2 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 558.0
PYH2_k127_4032977_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 464.0
PYH2_k127_4032977_4 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 463.0
PYH2_k127_4032977_5 Saccharopine dehydrogenase K03340 - 1.4.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
PYH2_k127_4032977_6 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 385.0
PYH2_k127_4032977_7 S-Adenosylmethionine synthetase K00789 - 2.5.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002611 372.0
PYH2_k127_4032977_8 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007897 316.0
PYH2_k127_4032977_9 - - - - 0.00000000000000000000000000000000000000000004681 166.0
PYH2_k127_4045310_0 PFAM ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 573.0
PYH2_k127_4045310_1 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 546.0
PYH2_k127_4045310_2 PFAM transglutaminase domain protein K22452 - 2.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001024 274.0
PYH2_k127_407450_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1587.0
PYH2_k127_407450_1 Pyridoxal-dependent decarboxylase K13745 - 4.1.1.86 1.102e-289 892.0
PYH2_k127_407450_10 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000000000000000009132 233.0
PYH2_k127_407450_11 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000001544 136.0
PYH2_k127_407450_2 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 537.0
PYH2_k127_407450_3 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 535.0
PYH2_k127_407450_4 ligase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 494.0
PYH2_k127_407450_5 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 486.0
PYH2_k127_407450_6 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 484.0
PYH2_k127_407450_7 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 450.0
PYH2_k127_407450_8 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 346.0
PYH2_k127_407450_9 Cytidylyltransferase family K00981 - 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000176 242.0
PYH2_k127_4075898_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 8.859e-220 684.0
PYH2_k127_4075898_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 419.0
PYH2_k127_4075898_2 riboflavin synthase alpha K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005145 357.0
PYH2_k127_4075898_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000001049 176.0
PYH2_k127_4100753_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.0 1086.0
PYH2_k127_4100753_1 PFAM glycosyl transferase family 9 K02849 - - 2.389e-217 678.0
PYH2_k127_4100753_2 glycosyl transferase group 1 K02844 - - 1.16e-201 632.0
PYH2_k127_4100753_3 COG4206 Outer membrane cobalamin receptor protein K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 465.0
PYH2_k127_4100753_4 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005068 315.0
PYH2_k127_4181430_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.0 1116.0
PYH2_k127_4181430_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 9.049e-296 908.0
PYH2_k127_4181430_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 565.0
PYH2_k127_4181430_3 COG0618 Exopolyphosphatase-related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003542 522.0
PYH2_k127_4181430_4 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008916 405.0
PYH2_k127_4181430_5 PFAM SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 403.0
PYH2_k127_4181430_6 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001958 297.0
PYH2_k127_4181430_7 Preprotein translocase K03210 - - 0.00000000000000000000000000000000000000000000000007146 179.0
PYH2_k127_4182773_0 Diguanylate cyclase - - - 2.689e-304 937.0
PYH2_k127_4182773_1 Abc transporter K15738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 359.0
PYH2_k127_4182773_2 DNA alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007542 237.0
PYH2_k127_4182773_3 PFAM zinc finger, DksA TraR C4-type - - - 0.00000000000000000000000000000000000000000000000000000000000000001637 226.0
PYH2_k127_4216180_0 ribonuclease, Rne Rng family K08301 - - 2.111e-303 931.0
PYH2_k127_4216180_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 9.802e-255 788.0
PYH2_k127_4216180_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003061 394.0
PYH2_k127_4216180_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 362.0
PYH2_k127_4216180_4 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008943 308.0
PYH2_k127_4216180_5 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 279.0
PYH2_k127_4216180_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K00640,K07062 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000003454 220.0
PYH2_k127_4216180_7 - - - - 0.0000000000000000000000000000000000000000000000000001418 186.0
PYH2_k127_4216180_8 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000001058 156.0
PYH2_k127_4216180_9 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000000000000000000000000009811 128.0
PYH2_k127_4223111_0 COG0474 Cation transport ATPase K01531 - 3.6.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 486.0
PYH2_k127_4223111_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 364.0
PYH2_k127_4230130_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 7.543e-201 626.0
PYH2_k127_4230130_1 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 443.0
PYH2_k127_4235298_0 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 1.58e-249 771.0
PYH2_k127_4235298_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.137e-248 769.0
PYH2_k127_4235298_2 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 5.11e-225 699.0
PYH2_k127_4235298_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 379.0
PYH2_k127_4235298_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002038 323.0
PYH2_k127_4235298_5 ATPase MipZ K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 327.0
PYH2_k127_4235298_6 - - - - 0.0000000000000092 77.0
PYH2_k127_4235298_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.0000002875 54.0
PYH2_k127_4257228_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 1.568e-211 660.0
PYH2_k127_4257228_1 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002411 238.0
PYH2_k127_4257228_2 Integral membrane protein CcmA involved in cell shape determination - - - 0.00000000000000000000000000000000000000000000000009849 177.0
PYH2_k127_4297186_0 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 3.555e-245 761.0
PYH2_k127_4297186_1 DsrC like protein K11179 - - 0.000000000000000000000000000000000000000000000000000000006122 201.0
PYH2_k127_4297186_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000008382 148.0
PYH2_k127_4297186_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000007145 74.0
PYH2_k127_432425_0 Protein of unknown function (DUF1015) - - - 3.678e-246 762.0
PYH2_k127_432425_1 RND efflux system, outer membrane lipoprotein K18139 - - 3.6e-226 711.0
PYH2_k127_432425_2 Phage integrase family - - - 0.00000000000000000000000000000000000000000000558 165.0
PYH2_k127_432425_3 AcrB/AcrD/AcrF family K18138 - - 0.000000000000000000000000000000002014 130.0
PYH2_k127_4331609_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1341.0
PYH2_k127_4331609_1 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 0.0 1053.0
PYH2_k127_4331609_2 PFAM EAL domain protein - - - 2.84e-225 702.0
PYH2_k127_4331609_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 3.135e-196 617.0
PYH2_k127_4336652_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 3.412e-259 803.0
PYH2_k127_4336652_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003054 597.0
PYH2_k127_4336652_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 473.0
PYH2_k127_4336652_3 Acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 461.0
PYH2_k127_4336652_4 Metal-dependent hydrolase K07043 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 454.0
PYH2_k127_4336652_5 D,D-heptose 1,7-bisphosphate phosphatase K03273 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0034200,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007426 347.0
PYH2_k127_4336652_6 Organic solvent tolerance protein K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 301.0
PYH2_k127_4336652_7 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000004038 246.0
PYH2_k127_4356856_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1763.0
PYH2_k127_4356856_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.721e-259 801.0
PYH2_k127_4356856_2 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 4.568e-231 717.0
PYH2_k127_4356856_3 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 588.0
PYH2_k127_4356856_4 peptidase K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000353 563.0
PYH2_k127_4356856_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 470.0
PYH2_k127_4356856_6 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003055 422.0
PYH2_k127_4356856_7 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000199 280.0
PYH2_k127_4356856_8 Protein of unknown function (DUF721) - - - 0.00000000000000000000000000000000000000000000000000000000000000000006412 233.0
PYH2_k127_4356856_9 - - - - 0.00004516 48.0
PYH2_k127_436501_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 1.493e-225 702.0
PYH2_k127_436501_1 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 536.0
PYH2_k127_4367463_0 Methyltransferase, YaeB family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003612 449.0
PYH2_k127_4367463_1 domain, Protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 359.0
PYH2_k127_4367463_2 - - - - 0.00000000000000000000000000000000000000595 150.0
PYH2_k127_4368336_0 4-vinyl reductase, 4VR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002463 247.0
PYH2_k127_4368336_1 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000007645 129.0
PYH2_k127_4368336_2 PFAM alpha beta hydrolase fold - - - 0.000000000000000000000000000003379 126.0
PYH2_k127_4451260_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 1.062e-216 677.0
PYH2_k127_4451260_1 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 301.0
PYH2_k127_4451260_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002459 261.0
PYH2_k127_4451260_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.00000000000000000000000000000000000000000000000000000000344 199.0
PYH2_k127_446871_0 alpha-glucan phosphorylase K00688 - 2.4.1.1 0.0 1672.0
PYH2_k127_446871_1 Peptidase M48 K06013 - 3.4.24.84 6.577e-251 776.0
PYH2_k127_446871_10 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000000000001346 179.0
PYH2_k127_446871_11 Glyoxalase-like domain - - - 0.00000000000000000000000000000002823 129.0
PYH2_k127_446871_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 2.369e-209 653.0
PYH2_k127_446871_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002166 539.0
PYH2_k127_446871_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 458.0
PYH2_k127_446871_5 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006948 367.0
PYH2_k127_446871_6 Belongs to the UPF0225 family K09858 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000103 247.0
PYH2_k127_446871_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003291 240.0
PYH2_k127_446871_8 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000001241 210.0
PYH2_k127_446871_9 - - - - 0.000000000000000000000000000000000000000000000000001654 183.0
PYH2_k127_4473370_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07673 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002232 532.0
PYH2_k127_4473370_1 helix_turn_helix, Lux Regulon K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008316 294.0
PYH2_k127_4478076_0 peptidase U62, modulator of DNA gyrase K03592 - - 1.26e-275 850.0
PYH2_k127_4478076_1 molybdenum cofactor K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 345.0
PYH2_k127_4478076_2 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005912 328.0
PYH2_k127_4478076_3 protein secretion by the type IV secretion system K00564,K02026,K10716,K11070,K13924,K14393 - 2.1.1.172,2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006941 291.0
PYH2_k127_4478076_4 Belongs to the UPF0307 family K09889 - - 0.00000000000000000000000000000000000000000000001837 184.0
PYH2_k127_4478076_5 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000001915 70.0
PYH2_k127_450384_0 PFAM Type II secretion system protein E K02670 - - 3.689e-224 699.0
PYH2_k127_450384_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 531.0
PYH2_k127_450384_2 - K17762 - - 0.000000000000000000000000000000000000000000000000000000000000000001315 227.0
PYH2_k127_450384_3 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.000000000000000000000000000000000000000000000000000000000003286 208.0
PYH2_k127_4505947_0 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004904 398.0
PYH2_k127_4505947_1 PFAM Metallophosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001568 244.0
PYH2_k127_4505947_2 Belongs to the universal stress protein A family - - - 0.0000000000000000000000000000005989 126.0
PYH2_k127_4520948_0 anti-sigma regulatory factor - - - 5.248e-225 698.0
PYH2_k127_4520948_1 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 4.043e-219 686.0
PYH2_k127_4520948_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K17763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005557 425.0
PYH2_k127_4520948_3 rhodanese-related sulfurtransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004045 270.0
PYH2_k127_4520948_4 GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000008626 222.0
PYH2_k127_4573417_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1886.0
PYH2_k127_4573417_1 fad dependent oxidoreductase K07137 - - 9.274e-299 917.0
PYH2_k127_4573417_10 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004237 246.0
PYH2_k127_4573417_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000000000009203 231.0
PYH2_k127_4573417_12 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000000000000002031 147.0
PYH2_k127_4573417_13 Ribosomal protein L30 K02907 - - 0.000000000000000000000000000002266 120.0
PYH2_k127_4573417_14 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000001275 68.0
PYH2_k127_4573417_2 Major facilitator Superfamily - - - 3.935e-273 846.0
PYH2_k127_4573417_3 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 1.004e-265 821.0
PYH2_k127_4573417_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 8.4e-206 642.0
PYH2_k127_4573417_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006281 416.0
PYH2_k127_4573417_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004728 317.0
PYH2_k127_4573417_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007768 296.0
PYH2_k127_4573417_8 binds to the 23S rRNA K02876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001458 269.0
PYH2_k127_4573417_9 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008029 254.0
PYH2_k127_4595030_0 Carbohydrate kinase - - - 4.07e-234 730.0
PYH2_k127_4595030_1 Atypical PilZ domain, cyclic di-GMP receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 319.0
PYH2_k127_4595030_2 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.0000000000000000000000000002169 113.0
PYH2_k127_4648690_0 Uncharacterised nucleotidyltransferase - - - 1.418e-205 642.0
PYH2_k127_4648690_1 ABC transporter transmembrane region K06148 - - 3.82e-200 624.0
PYH2_k127_4648690_2 HPr kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 580.0
PYH2_k127_4648690_3 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 317.0
PYH2_k127_4648690_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 296.0
PYH2_k127_4648690_5 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
PYH2_k127_4648690_6 Autotransporter beta-domain K12685 - - 0.0000000000000000000000000000000000000000001708 168.0
PYH2_k127_4648690_7 - - - - 0.000000000000000000000000000000000000000002346 157.0
PYH2_k127_4675219_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1651.0
PYH2_k127_4675219_1 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 5.827e-197 615.0
PYH2_k127_4675219_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003932 453.0
PYH2_k127_4675219_3 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009819 451.0
PYH2_k127_4675219_4 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004825 229.0
PYH2_k127_4675219_5 Helicase K03657 - 3.6.4.12 0.00000000000000000000004638 98.0
PYH2_k127_468568_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 2.527e-256 792.0
PYH2_k127_468568_1 histidine kinase HAMP region domain protein K07645 - 2.7.13.3 2.375e-244 762.0
PYH2_k127_468568_2 Diguanylate cyclase K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002901 579.0
PYH2_k127_468568_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 464.0
PYH2_k127_468568_4 response regulator K02483,K07666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 393.0
PYH2_k127_468568_5 PFAM Di-haem cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 287.0
PYH2_k127_468568_6 Domain of unknown function (DUF1924) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004762 245.0
PYH2_k127_468568_7 - - - - 0.00000009169 56.0
PYH2_k127_4693207_0 Ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.0 1394.0
PYH2_k127_4693207_1 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 2.136e-267 824.0
PYH2_k127_4693207_2 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003406 573.0
PYH2_k127_4693207_3 anaerobic ribonucleoside-triphosphate reductase activating protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 401.0
PYH2_k127_4693207_4 NapC/NirT cytochrome c family, N-terminal region K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007361 282.0
PYH2_k127_4693207_5 Pfam cytochrome c K17230 - - 0.000000000000000000000000000000000000000000000000000000000000000001108 228.0
PYH2_k127_4693207_6 Sterol-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000007151 207.0
PYH2_k127_4693207_7 cytochrome c-type protein K02569 - - 0.00000000000000000000000000000000000000000000000000000001219 204.0
PYH2_k127_4693207_8 Pfam cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000000000003695 192.0
PYH2_k127_4693207_9 Anaerobic ribonucleoside-triphosphate reductase - - - 0.000000000000000000000000000000007199 129.0
PYH2_k127_4703690_0 CAAX amino terminal protease family - - - 0.00000000000000000000000000003722 128.0
PYH2_k127_4703690_1 Acetyltransferase (GNAT) family - - - 0.00000000000003338 76.0
PYH2_k127_4703690_2 - - - - 0.0000000002 67.0
PYH2_k127_4735432_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1294.0
PYH2_k127_4735432_1 Aminotransferase K00812 - 2.6.1.1 3.6e-245 759.0
PYH2_k127_4735432_2 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009648 343.0
PYH2_k127_4735432_3 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001615 276.0
PYH2_k127_4735432_4 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000008164 260.0
PYH2_k127_4735432_5 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000000000000000000836 151.0
PYH2_k127_4750906_0 SMART Tetratricopeptide domain protein - - - 3.825e-303 934.0
PYH2_k127_4750906_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 1.505e-197 616.0
PYH2_k127_4750906_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001604 530.0
PYH2_k127_4750906_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 377.0
PYH2_k127_4750906_4 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006256 329.0
PYH2_k127_4750906_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003306 307.0
PYH2_k127_4777684_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.712e-267 827.0
PYH2_k127_4777684_1 fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 9.642e-216 671.0
PYH2_k127_4777684_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 583.0
PYH2_k127_4777684_3 Transcriptional regulator K21703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005194 554.0
PYH2_k127_4777684_4 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008436 478.0
PYH2_k127_4777684_5 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 328.0
PYH2_k127_4778347_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 4.193e-316 970.0
PYH2_k127_4778347_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 6.615e-283 872.0
PYH2_k127_4778347_2 peptidase - - - 8.777e-211 662.0
PYH2_k127_4778347_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 579.0
PYH2_k127_4778347_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 575.0
PYH2_k127_4778347_5 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000001658 200.0
PYH2_k127_4778347_6 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000006493 160.0
PYH2_k127_4931358_0 Sulfatase K01135 - 3.1.6.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 583.0
PYH2_k127_4931358_1 Domain of unknown function (DUF4964) - - - 0.00000000000000000001615 91.0
PYH2_k127_4967588_0 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0 1146.0
PYH2_k127_4967588_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 1.61e-210 657.0
PYH2_k127_4967588_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 554.0
PYH2_k127_4967588_3 Transcriptional regulator K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005936 436.0
PYH2_k127_4967588_4 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006765 413.0
PYH2_k127_4967588_5 abc transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009826 383.0
PYH2_k127_4967588_6 COG2755 Lysophospholipase L1 and related esterases K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.000000000000000000000000000000000000000001289 163.0
PYH2_k127_5019711_0 FAD linked oxidase domain protein - - - 0.0 1810.0
PYH2_k127_5019711_1 - - - - 8.199e-303 933.0
PYH2_k127_5019711_2 Histidine kinase K07636 - 2.7.13.3 1.47e-262 812.0
PYH2_k127_5019711_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 488.0
PYH2_k127_5019711_4 import inner membrane translocase, subunit Tim44 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 454.0
PYH2_k127_5019711_5 phosphate regulon transcriptional regulatory protein PhoB K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 450.0
PYH2_k127_5019711_6 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004597 273.0
PYH2_k127_5023381_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 0.0 1262.0
PYH2_k127_5023381_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 595.0
PYH2_k127_5023381_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000000000000002488 224.0
PYH2_k127_5023381_3 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000000000001886 99.0
PYH2_k127_5027288_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 7.737e-282 868.0
PYH2_k127_5027288_1 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 600.0
PYH2_k127_5027288_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 421.0
PYH2_k127_5041324_0 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 1.394e-222 700.0
PYH2_k127_5041324_1 Aminotransferase class I and II K02225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 400.0
PYH2_k127_5041324_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 336.0
PYH2_k127_5041324_3 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 299.0
PYH2_k127_5041324_4 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008818,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016020,GO:0016740,GO:0016772,GO:0016780,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.8.26 0.000000000000000000000000000000000000000000000000000000000000000000000005071 250.0
PYH2_k127_5041324_5 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000002176 222.0
PYH2_k127_5041324_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000000000000000000000000000000000006963 198.0
PYH2_k127_5041324_8 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000001452 110.0
PYH2_k127_5058325_0 Protein of unknown function (DUF3417) K00688 - 2.4.1.1 0.0 1125.0
PYH2_k127_5058325_1 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 4.393e-289 889.0
PYH2_k127_5058325_2 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 2.716e-270 842.0
PYH2_k127_5058325_3 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 9.328e-239 739.0
PYH2_k127_5058325_4 Uncharacterized protein conserved in bacteria (DUF2219) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 482.0
PYH2_k127_5058325_5 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000000000000000001591 164.0
PYH2_k127_5058325_6 translation initiation factor activity K06996 - - 0.00000000000000000000000000000000000000002225 157.0
PYH2_k127_5058325_7 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000161 135.0
PYH2_k127_5058325_8 - - - - 0.00000000000000000001014 93.0
PYH2_k127_5058325_9 Short C-terminal domain K08982 - - 0.0000000000001542 73.0
PYH2_k127_5060857_0 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 1.119e-319 984.0
PYH2_k127_5060857_1 Flagellar Assembly Protein A K09749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 417.0
PYH2_k127_5060857_2 Isochorismate synthase K01851,K02361,K02552 - 5.4.4.2 0.00000000000000001374 82.0
PYH2_k127_5064802_0 PFAM FAD linked oxidase domain protein K00102,K03777 - 1.1.2.4,1.1.5.12 8.788e-283 870.0
PYH2_k127_5064802_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009377 425.0
PYH2_k127_5064802_2 PFAM Sporulation domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007077 400.0
PYH2_k127_5064802_3 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 343.0
PYH2_k127_5064802_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.0000000000000000000000000000000000001067 141.0
PYH2_k127_507998_0 Nitric oxide reductase K04561 - 1.7.2.5 4.714e-290 891.0
PYH2_k127_507998_1 Belongs to the heme-copper respiratory oxidase family - - - 1.873e-228 713.0
PYH2_k127_507998_10 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000000000005277 175.0
PYH2_k127_507998_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 594.0
PYH2_k127_507998_3 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 583.0
PYH2_k127_507998_4 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 495.0
PYH2_k127_507998_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004233 473.0
PYH2_k127_507998_6 cytochrome C K02305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 295.0
PYH2_k127_507998_7 Hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007803 269.0
PYH2_k127_507998_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000071 213.0
PYH2_k127_507998_9 Uncharacterized conserved protein (DUF2249) - - - 0.0000000000000000000000000000000000000000000000000372 179.0
PYH2_k127_5105770_0 Urea ABC transporter, urea binding protein K11959 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008179 499.0
PYH2_k127_5105770_1 acetyltransferase K03830 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 295.0
PYH2_k127_5111080_0 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.0 1132.0
PYH2_k127_5111080_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 0.0 1082.0
PYH2_k127_5111080_10 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 362.0
PYH2_k127_5111080_11 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 308.0
PYH2_k127_5111080_12 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000000000003389 126.0
PYH2_k127_5111080_13 Modulator of Rho-dependent transcription termination (ROF) K19000 - - 0.00000000000000000000000000001787 123.0
PYH2_k127_5111080_2 acetyl-CoA carboxylase, biotin carboxylase K01959 - 6.4.1.1 1.079e-304 935.0
PYH2_k127_5111080_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 3.338e-209 651.0
PYH2_k127_5111080_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 9.521e-201 626.0
PYH2_k127_5111080_5 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 7.674e-196 612.0
PYH2_k127_5111080_6 peptidase, S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 590.0
PYH2_k127_5111080_7 malonyl CoA-acyl carrier protein transacylase K00645,K13935,K15355 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 553.0
PYH2_k127_5111080_8 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 423.0
PYH2_k127_5111080_9 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 404.0
PYH2_k127_5127823_0 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003471 525.0
PYH2_k127_5127823_1 Acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007286 343.0
PYH2_k127_5127823_2 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004229 285.0
PYH2_k127_5127823_3 transferase activity, transferring acyl groups other than amino-acyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000003538 236.0
PYH2_k127_5127823_4 Zinc-binding dehydrogenase - - - 0.0000000000000004197 79.0
PYH2_k127_5147133_0 PAS fold K10715,K20974 - 2.7.13.3 5.561e-260 851.0
PYH2_k127_5147133_1 MHYT domain - - - 0.000000000000000000000000000000000000000001678 181.0
PYH2_k127_5147133_2 Histidine kinase - - - 0.00000000000000000000000000001392 119.0
PYH2_k127_5148523_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1064.0
PYH2_k127_5148523_1 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 593.0
PYH2_k127_5148523_2 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.00000000000000000000000000000000002242 142.0
PYH2_k127_5154514_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 468.0
PYH2_k127_5154514_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006642 464.0
PYH2_k127_5161275_0 PFAM membrane protein involved in aromatic hydrocarbon degradation K06076 - - 2.531e-255 793.0
PYH2_k127_5161275_1 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002266 362.0
PYH2_k127_5161275_2 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002765 236.0
PYH2_k127_5165097_0 Abc transporter K06158 - - 0.0 1145.0
PYH2_k127_5165097_1 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1056.0
PYH2_k127_5165097_2 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835 - 5.4.2.2 6.23e-322 989.0
PYH2_k127_5165097_3 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 552.0
PYH2_k127_5165097_4 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 531.0
PYH2_k127_5165097_5 had-superfamily hydrolase subfamily ia, variant 3 K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 372.0
PYH2_k127_5165097_6 transferase hexapeptide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 338.0
PYH2_k127_5165097_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007741 358.0
PYH2_k127_5165097_8 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000000000000000000000001339 209.0
PYH2_k127_5174267_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 581.0
PYH2_k127_5174267_1 Hsp70 protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000003177 241.0
PYH2_k127_5174267_2 Peptidase S24-like - - - 0.000000000000000000000000000000000000000004478 157.0
PYH2_k127_5174267_3 Diguanylate cyclase - - - 0.000000000000009225 78.0
PYH2_k127_5196268_0 LppC putative lipoprotein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 576.0
PYH2_k127_5196268_1 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 390.0
PYH2_k127_5196268_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 345.0
PYH2_k127_5196268_3 PFAM transport-associated - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 321.0
PYH2_k127_5196268_4 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000001562 236.0
PYH2_k127_5196268_5 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000000000000003109 152.0
PYH2_k127_5210591_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0 1146.0
PYH2_k127_5210591_1 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 1.051e-294 906.0
PYH2_k127_5210591_2 phosphoglucomutase phosphomannomutase alpha beta alpha domain II K01835,K01840,K15778 GO:0000271,GO:0000287,GO:0003674,GO:0003824,GO:0004614,GO:0004615,GO:0005488,GO:0005975,GO:0005976,GO:0006082,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009243,GO:0009244,GO:0009311,GO:0009312,GO:0009405,GO:0009987,GO:0016051,GO:0016053,GO:0016853,GO:0016866,GO:0016868,GO:0017144,GO:0019752,GO:0033692,GO:0034637,GO:0034645,GO:0042120,GO:0042121,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044283,GO:0044419,GO:0046394,GO:0046401,GO:0046402,GO:0046872,GO:0051704,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 5.4.2.2,5.4.2.8 2.027e-290 895.0
PYH2_k127_5210591_3 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 3.949e-196 612.0
PYH2_k127_5210591_4 heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 601.0
PYH2_k127_5210591_5 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 452.0
PYH2_k127_5210591_6 Bacterial type II and III secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 404.0
PYH2_k127_5210591_7 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 387.0
PYH2_k127_5210591_8 protein conserved in bacteria - - - 0.00000000000000000000000000000000000006363 142.0
PYH2_k127_5216769_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1325.0
PYH2_k127_5216769_1 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 515.0
PYH2_k127_5216769_2 serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002755 460.0
PYH2_k127_5216769_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 429.0
PYH2_k127_5238245_0 Abc transporter K06147 - - 0.0 1095.0
PYH2_k127_5238245_1 Heat shock 70 kDa protein K04043 - - 1.5e-297 923.0
PYH2_k127_5238245_10 Peptidoglycan-binding domain 1 protein K03194,K07273,K08307,K08309,K12089 - - 0.00000000000000000000000000000000000000000000000000000000000000001741 233.0
PYH2_k127_5238245_11 Translation initiation factor K03113 - - 0.00000000000000000000000000000000000000000000000000000000000000005069 225.0
PYH2_k127_5238245_12 diguanylate cyclase K13590 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000001169 204.0
PYH2_k127_5238245_13 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000000000000000000000001524 185.0
PYH2_k127_5238245_14 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000000000000000000000000000001096 147.0
PYH2_k127_5238245_15 Cold shock protein K03704 - - 0.0000000000000000000000000000000000002803 140.0
PYH2_k127_5238245_2 Aminotransferase K00821 - 2.6.1.11,2.6.1.17 4.82e-244 755.0
PYH2_k127_5238245_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 554.0
PYH2_k127_5238245_4 Membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 563.0
PYH2_k127_5238245_5 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 510.0
PYH2_k127_5238245_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 466.0
PYH2_k127_5238245_7 PFAM PEBP family protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008061 300.0
PYH2_k127_5238245_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000912 286.0
PYH2_k127_5238245_9 Nitroreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009399 276.0
PYH2_k127_528973_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 8.75e-211 656.0
PYH2_k127_528973_1 Histidine kinase K07675,K20263 GO:0000155,GO:0000160,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0035556,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 556.0
PYH2_k127_528973_2 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008861 389.0
PYH2_k127_528973_3 - - - - 0.000000000000000000000000000000000001806 139.0
PYH2_k127_5323696_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 1.075e-308 945.0
PYH2_k127_5323696_1 DMSO reductase anchor subunit (DmsC) K21309 - - 7.137e-194 608.0
PYH2_k127_5323696_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 516.0
PYH2_k127_5323696_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 326.0
PYH2_k127_5327546_0 glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001797 534.0
PYH2_k127_5327546_1 Transposase IS200 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 385.0
PYH2_k127_5420538_0 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 2.175e-278 857.0
PYH2_k127_5420538_1 Superoxide dismutase K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 284.0
PYH2_k127_5420538_2 Rhodanese domain protein - - - 0.0000000000000000000000000000000000000000000000000000001719 198.0
PYH2_k127_5420538_3 Chromate resistance - - - 0.00000000000000000000000000002192 117.0
PYH2_k127_5420538_4 Chromate resistance exported protein - - - 0.000000000006282 67.0
PYH2_k127_5526027_0 - - - - 0.000000000000000000000000000000000000000000000000000001036 201.0
PYH2_k127_5526027_1 - - - - 0.00000000000000000000000000000002042 135.0
PYH2_k127_5526027_2 translation initiation factor activity K07126,K08884,K12132 - 2.7.11.1 0.0005376 53.0
PYH2_k127_5566868_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1304.0
PYH2_k127_5566868_1 4Fe-4S dicluster domain - - - 0.0 1016.0
PYH2_k127_5566868_10 sulfur relay protein TusD DsrE K07235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007542 237.0
PYH2_k127_5566868_11 DsrC like protein K11179 - - 0.00000000000000000000000000000000000000000000000000000000000000000006618 231.0
PYH2_k127_5566868_12 DsrH like protein K07237 - - 0.0000000000000000000000000000000000000000000000000000002946 194.0
PYH2_k127_5566868_2 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 6.84e-244 752.0
PYH2_k127_5566868_3 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006445 598.0
PYH2_k127_5566868_4 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 511.0
PYH2_k127_5566868_5 Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 481.0
PYH2_k127_5566868_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 323.0
PYH2_k127_5566868_7 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 308.0
PYH2_k127_5566868_8 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008371 269.0
PYH2_k127_5566868_9 Sulfur relay protein TusC DsrF K07236 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005259 258.0
PYH2_k127_559220_0 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 5.439e-252 797.0
PYH2_k127_5624936_0 RNA binding S1 domain protein K06959 - - 0.0 1421.0
PYH2_k127_5624936_1 Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system K02017 - 3.6.3.29 6.624e-209 655.0
PYH2_k127_5624936_10 - - - - 0.00000000000000000000000000000001093 129.0
PYH2_k127_5624936_2 Cation efflux family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
PYH2_k127_5624936_3 serves to protect cells from the toxic effects of hydrogen peroxide K03781 - 1.11.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 514.0
PYH2_k127_5624936_4 Molybdate ABC transporter K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 437.0
PYH2_k127_5624936_5 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007825 413.0
PYH2_k127_5624936_6 Protein of unknown function (DUF1345) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 346.0
PYH2_k127_5624936_7 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000003862 211.0
PYH2_k127_5624936_8 Belongs to the BI1 family K19416 - - 0.000000000000000000000000000000000000000000004494 164.0
PYH2_k127_5624936_9 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000548 144.0
PYH2_k127_5632156_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 6.642e-199 621.0
PYH2_k127_5632156_1 Opioid growth factor receptor (OGFr) conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 311.0
PYH2_k127_5632156_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000001586 184.0
PYH2_k127_5632156_3 belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000001395 174.0
PYH2_k127_5632156_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000000000002439 154.0
PYH2_k127_5633137_0 COG2201 Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 370.0
PYH2_k127_5633137_1 DsrE/DsrF-like family K06039 - - 0.00000000000000000000000387 105.0
PYH2_k127_5640912_0 Metal-dependent hydrolase HDOD - - - 0.0 1357.0
PYH2_k127_5640912_1 Radical_SAM C-terminal domain K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 392.0
PYH2_k127_5640912_2 Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009916 323.0
PYH2_k127_5640912_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007496 243.0
PYH2_k127_5643513_0 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 426.0
PYH2_k127_5643513_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006549 359.0
PYH2_k127_5643513_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000001836 226.0
PYH2_k127_5679727_0 YidE YbjL duplication K07085 - - 4.885e-245 767.0
PYH2_k127_5679727_1 Biotin-lipoyl like K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005105 473.0
PYH2_k127_5679727_2 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 GO:0000302,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016684,GO:0016999,GO:0017001,GO:0017144,GO:0020037,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042542,GO:0042737,GO:0042743,GO:0042744,GO:0044237,GO:0044248,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0046906,GO:0048037,GO:0050896,GO:0051186,GO:0051187,GO:0051716,GO:0055114,GO:0070301,GO:0070887,GO:0071236,GO:0072593,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901363,GO:1901700,GO:1901701,GO:1990748 1.11.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 396.0
PYH2_k127_5679727_3 D-isomer specific 2-hydroxyacid dehydrogenase K03778 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000008172 265.0
PYH2_k127_5680105_0 LytR cell envelope-related transcriptional attenuator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002784 269.0
PYH2_k127_5680105_1 SMART Sel1 domain protein repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000006199 238.0
PYH2_k127_5680105_2 Transcriptional regulatory protein - - - 0.00002507 46.0
PYH2_k127_5683246_0 cell redox homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002307 499.0
PYH2_k127_5683246_1 PEP-CTERM motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003244 492.0
PYH2_k127_5683246_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004883 318.0
PYH2_k127_5683246_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007385 247.0
PYH2_k127_5683246_4 Glycine zipper 2TM domain - - - 0.000000000000000000000000000000000000000000000000000009042 190.0
PYH2_k127_5723350_0 pilus assembly protein FimV K08086 - - 0.0 1468.0
PYH2_k127_5723350_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 1.577e-263 811.0
PYH2_k127_5723350_10 colicin v production K03558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 289.0
PYH2_k127_5723350_11 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000002818 211.0
PYH2_k127_5723350_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 1.623e-259 802.0
PYH2_k127_5723350_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 571.0
PYH2_k127_5723350_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 523.0
PYH2_k127_5723350_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 492.0
PYH2_k127_5723350_6 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006478 443.0
PYH2_k127_5723350_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004246 390.0
PYH2_k127_5723350_8 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002899 307.0
PYH2_k127_5723350_9 PFAM Sporulation domain protein K03749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008793 305.0
PYH2_k127_5729874_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 513.0
PYH2_k127_5729874_1 histidine kinase A domain protein K07679 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 458.0
PYH2_k127_5729874_2 response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 318.0
PYH2_k127_5730368_0 RimK-like ATPgrasp N-terminal domain - - - 1.172e-248 777.0
PYH2_k127_5730368_1 PFAM VanZ family protein - - - 1.09e-234 730.0
PYH2_k127_5730368_2 single-stranded DNA 5'-3' exodeoxyribonuclease activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 595.0
PYH2_k127_5730368_3 Glutamate-cysteine ligase family 2(GCS2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 599.0
PYH2_k127_5730368_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 434.0
PYH2_k127_5730368_5 N-formylglutamate amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 339.0
PYH2_k127_5730368_6 Protein of unknown function, DUF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006554 293.0
PYH2_k127_5730368_7 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000004406 216.0
PYH2_k127_5730368_8 MazG-like family - - - 0.0000000000000000000000000000007991 126.0
PYH2_k127_5744719_0 membrane-bound lytic murein transglycosylase K08304 - - 4.382e-222 691.0
PYH2_k127_5744719_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 449.0
PYH2_k127_5744719_2 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006042 445.0
PYH2_k127_5744719_3 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 384.0
PYH2_k127_5744719_4 PFAM ApaG domain protein K06195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003394 256.0
PYH2_k127_5773717_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 0.0 1000.0
PYH2_k127_5773717_1 Sodium:solute symporter family K14393 - - 5.047e-219 692.0
PYH2_k127_5773717_2 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 497.0
PYH2_k127_5773717_3 Two component transcriptional regulator, winged helix family K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005384 308.0
PYH2_k127_5773717_4 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000000000000000000006563 175.0
PYH2_k127_5792206_0 Ornithine-acyl acyl carrier protein N-acyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003162 494.0
PYH2_k127_5792206_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 427.0
PYH2_k127_5792206_2 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 374.0
PYH2_k127_5792206_3 it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in the 3' to 5' direction K03656 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 311.0
PYH2_k127_5792206_4 17 kDa surface antigen K06077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001013 247.0
PYH2_k127_5792206_5 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000004055 185.0
PYH2_k127_5844019_0 Nitroreductase family - - - 1.134e-215 678.0
PYH2_k127_5844019_1 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 291.0
PYH2_k127_5844019_2 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.000000000000000000000000000000000000000000000000000000000004951 207.0
PYH2_k127_5844019_3 - - - - 0.000000000000000000000000000000000000000000000000000002699 194.0
PYH2_k127_5849481_0 NMT1-like family - - - 0.0000000000000000000153 103.0
PYH2_k127_5849481_1 Lytic murein transglycosylase B K08305 - - 0.0000000000000000001501 89.0
PYH2_k127_5864624_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 444.0
PYH2_k127_5864624_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006667 402.0
PYH2_k127_5864624_2 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 401.0
PYH2_k127_5864624_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000000281 202.0
PYH2_k127_5864624_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000000000000008816 201.0
PYH2_k127_5864624_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000000000000000000001809 164.0
PYH2_k127_5897132_0 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006753 472.0
PYH2_k127_5897132_1 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.00000000000000000000000000000000000000000000000000000001652 200.0
PYH2_k127_5903390_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 7.637e-258 802.0
PYH2_k127_5903390_1 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004584 577.0
PYH2_k127_5903390_11 - - - - 0.00000000004749 64.0
PYH2_k127_5903390_2 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004022 463.0
PYH2_k127_5903390_3 methyltransferase activity K21310 - 2.1.1.334 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 390.0
PYH2_k127_5903390_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 300.0
PYH2_k127_5903390_7 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000442 196.0
PYH2_k127_5903390_9 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000004421 108.0
PYH2_k127_5911689_0 4 iron, 4 sulfur cluster binding K00226,K02574 - 1.3.98.1 4.928e-205 640.0
PYH2_k127_5911689_1 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 479.0
PYH2_k127_5911689_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 447.0
PYH2_k127_5911689_3 Cytochrome C biogenesis protein transmembrane region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 376.0
PYH2_k127_5911689_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 355.0
PYH2_k127_5918742_0 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 418.0
PYH2_k127_5918742_1 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007392 400.0
PYH2_k127_5918742_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000001587 180.0
PYH2_k127_5950869_0 Peptidase U32 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 577.0
PYH2_k127_5950869_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001829 283.0
PYH2_k127_5950869_2 peptidase, U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000001666 197.0
PYH2_k127_5950869_3 DsrE/DsrF-like family K06039 - - 0.00000000000000000000002263 103.0
PYH2_k127_5975260_0 fad dependent oxidoreductase K07137 - - 2.559e-284 880.0
PYH2_k127_5975260_1 ABC1 family K03688 - - 1.427e-253 793.0
PYH2_k127_5975260_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 6.415e-204 637.0
PYH2_k127_5975260_3 - - - - 0.000000000000000000000000000000000000000000000000000000001026 207.0
PYH2_k127_6021041_0 Dynamin family - - - 0.0 1079.0
PYH2_k127_6021041_1 Belongs to the peptidase M16 family K07263 - - 8.385e-272 843.0
PYH2_k127_6021041_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007053 580.0
PYH2_k127_6021041_3 PFAM peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 522.0
PYH2_k127_6021041_4 Cell division ATP-binding protein ftsE K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 409.0
PYH2_k127_6021041_5 methyltransferase K08316 - 2.1.1.171 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 364.0
PYH2_k127_6021041_6 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000002716 229.0
PYH2_k127_6021041_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000522 179.0
PYH2_k127_6021041_9 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000005121 49.0
PYH2_k127_6025333_0 Diguanylate cyclase - - - 0.0 1031.0
PYH2_k127_6025333_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0 1017.0
PYH2_k127_6025333_2 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 5.177e-222 692.0
PYH2_k127_6025333_3 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 311.0
PYH2_k127_6025333_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000004866 170.0
PYH2_k127_6025333_5 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.000000000000000000000002838 104.0
PYH2_k127_6063519_0 Fibronectin type III-like domain K05349 - 3.2.1.21 1.829e-198 626.0
PYH2_k127_6063519_1 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
PYH2_k127_6063519_2 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K10824 - 3.6.3.24 0.00000001269 56.0
PYH2_k127_6076333_0 protein SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 381.0
PYH2_k127_6076333_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 344.0
PYH2_k127_6076333_2 PFAM YaeQ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008473 341.0
PYH2_k127_6076333_3 Thioredoxin K05838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002326 244.0
PYH2_k127_6076333_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000401 238.0
PYH2_k127_6076333_5 - - - - 0.000000000000000000000000000000000000000000000054 171.0
PYH2_k127_6076333_6 RNA-binding K14761 - - 0.00000000000000000000000000000000007546 135.0
PYH2_k127_6081066_0 Urea ABC transporter, urea binding protein K11959 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 593.0
PYH2_k127_6081066_1 Histidine kinase K20974 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 308.0
PYH2_k127_6096191_0 histidine kinase HAMP region domain protein K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007192 597.0
PYH2_k127_6096191_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 538.0
PYH2_k127_6096191_2 hydrolase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 512.0
PYH2_k127_6096191_3 orn lys arg decarboxylase K01584 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 374.0
PYH2_k127_6096191_4 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 310.0
PYH2_k127_6096191_5 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007757 314.0
PYH2_k127_6096721_0 FAD dependent oxidoreductase K09471 - - 3.106e-222 698.0
PYH2_k127_6096721_1 NMT1-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 344.0
PYH2_k127_6096721_2 Saccharopine dehydrogenase C-terminal domain K00808 - 2.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 292.0
PYH2_k127_6102868_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 1.086e-263 815.0
PYH2_k127_6102868_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000007557 204.0
PYH2_k127_6157650_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 2.679e-223 698.0
PYH2_k127_6157650_1 PFAM Outer membrane efflux protein - - - 1.144e-200 629.0
PYH2_k127_6157650_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.000008409 48.0
PYH2_k127_6201895_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0 1179.0
PYH2_k127_6201895_1 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 3.343e-288 902.0
PYH2_k127_6201895_10 PFAM FecR protein - - - 0.0000000000000000000000000000009583 139.0
PYH2_k127_6201895_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003255 443.0
PYH2_k127_6201895_3 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 407.0
PYH2_k127_6201895_4 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 385.0
PYH2_k127_6201895_5 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005779 355.0
PYH2_k127_6201895_6 Protein of unknown function (DUF560) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002978 290.0
PYH2_k127_6201895_7 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002635 270.0
PYH2_k127_6201895_8 PFAM CHAD domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001366 249.0
PYH2_k127_6201895_9 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.00000000000000000000000000000000000008726 144.0
PYH2_k127_6250321_0 von Willebrand factor, type A - - - 0.0 1382.0
PYH2_k127_6264045_0 DNA polymerase X family K02347 - - 3.184e-311 959.0
PYH2_k127_6264045_1 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.585e-248 769.0
PYH2_k127_6264045_10 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000009947 190.0
PYH2_k127_6264045_11 - - - - 0.00000000000000000000000000000000001254 142.0
PYH2_k127_6264045_12 NTPase - - - 0.00000000000000000000000000000053 124.0
PYH2_k127_6264045_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004471 518.0
PYH2_k127_6264045_3 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 482.0
PYH2_k127_6264045_4 geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 465.0
PYH2_k127_6264045_5 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 411.0
PYH2_k127_6264045_6 ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007951 304.0
PYH2_k127_6264045_7 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000004829 237.0
PYH2_k127_6264045_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001002 229.0
PYH2_k127_6264045_9 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000002773 188.0
PYH2_k127_6270266_0 Part of a membrane complex involved in electron transport K03615 - - 2.518e-292 902.0
PYH2_k127_6270266_1 FIST_C - - - 2.513e-220 685.0
PYH2_k127_6270266_2 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 5.254e-219 681.0
PYH2_k127_6270266_3 Part of a membrane complex involved in electron transport K03614 - - 4.229e-195 612.0
PYH2_k127_6270266_4 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 421.0
PYH2_k127_6270266_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 416.0
PYH2_k127_6270266_6 Part of a membrane complex involved in electron transport K03612 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 387.0
PYH2_k127_6270266_7 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 351.0
PYH2_k127_6270266_8 Part of a membrane complex involved in electron transport K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003271 342.0
PYH2_k127_6270266_9 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000001032 137.0
PYH2_k127_6275923_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1172.0
PYH2_k127_6275923_1 SMART AAA ATPase K02450 - - 9.566e-295 910.0
PYH2_k127_6275923_2 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 527.0
PYH2_k127_6275923_3 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009048 491.0
PYH2_k127_6275923_4 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000000000000000000000000006094 218.0
PYH2_k127_6275923_5 SpoIIAA-like - - - 0.000000000000000000000000000000000000000000000000000000001362 201.0
PYH2_k127_6275923_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000000000000000000000004659 153.0
PYH2_k127_6330672_0 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 614.0
PYH2_k127_6330672_1 cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 439.0
PYH2_k127_6468773_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 1.813e-266 821.0
PYH2_k127_6468773_1 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 4.268e-210 655.0
PYH2_k127_6468773_2 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 426.0
PYH2_k127_6468773_3 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 301.0
PYH2_k127_6468773_4 DJ-1/PfpI family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009287 251.0
PYH2_k127_6468773_5 Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions K09913 - 2.4.2.1,2.4.2.2 0.000000000000000000000000000000000000000000000000000000000000000001559 227.0
PYH2_k127_6499014_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007494 612.0
PYH2_k127_6499014_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007042 246.0
PYH2_k127_6500538_0 DinB superfamily - - - 0.0 1409.0
PYH2_k127_6500538_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 1.65e-262 814.0
PYH2_k127_6500538_2 Histidine kinase K07673 - 2.7.13.3 1.599e-244 757.0
PYH2_k127_6500538_3 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 564.0
PYH2_k127_6500538_4 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004333 497.0
PYH2_k127_6500538_5 response regulator K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 421.0
PYH2_k127_6500538_6 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 289.0
PYH2_k127_6500538_7 Peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000006023 248.0
PYH2_k127_6500538_8 had-superfamily hydrolase subfamily ia, variant 3 K07025 - - 0.00000000000000000000000000001371 117.0
PYH2_k127_6529606_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 5.793e-286 932.0
PYH2_k127_6529606_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000001709 214.0
PYH2_k127_6548811_0 Flagellar motor switch protein K02416 - - 2.043e-205 640.0
PYH2_k127_6548811_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 556.0
PYH2_k127_6548811_10 Role in flagellar biosynthesis K02420 - - 0.0000000000000000000000000000000000000001446 153.0
PYH2_k127_6548811_12 PFAM H transporting two-sector ATPase alpha beta subunit central region K02412 - 3.6.3.14 0.00000000000009566 70.0
PYH2_k127_6548811_2 Flagellar hook-length control protein K02414 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009976 495.0
PYH2_k127_6548811_3 Flagellar biosynthetic protein FliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 462.0
PYH2_k127_6548811_4 Plays a role in the flagellum-specific transport system K02419 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002331 421.0
PYH2_k127_6548811_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004128 285.0
PYH2_k127_6548811_6 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 284.0
PYH2_k127_6548811_7 Flagellar export protein FliJ K02413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003828 265.0
PYH2_k127_6548811_8 PFAM flagellar biosynthesis protein, FliO K02418 - - 0.00000000000000000000000000000000000000000000000000000000000000001781 226.0
PYH2_k127_6548811_9 flagellar motor switch protein K02417 - - 0.000000000000000000000000000000000000000000000000719 180.0
PYH2_k127_6549998_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.001e-311 955.0
PYH2_k127_6549998_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 5.26e-233 726.0
PYH2_k127_6549998_2 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 1.822e-226 706.0
PYH2_k127_6549998_3 endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 499.0
PYH2_k127_6549998_4 ABC transporter transmembrane region K12541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005018 430.0
PYH2_k127_6549998_5 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 289.0
PYH2_k127_6550970_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 0.0 1019.0
PYH2_k127_6550970_1 'signal transduction protein - - - 7.121e-265 820.0
PYH2_k127_6550970_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903,K14067 - 6.2.1.5,6.2.1.9 6.809e-231 717.0
PYH2_k127_6550970_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008261 546.0
PYH2_k127_6550970_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 521.0
PYH2_k127_6550970_5 Belongs to the P(II) protein family K04751,K04752 - - 0.00000000000000000000000000000000000000000000000000000000000009191 213.0
PYH2_k127_6550970_6 PFAM Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000116 206.0
PYH2_k127_6550970_7 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000007501 153.0
PYH2_k127_6550970_8 Copper binding periplasmic protein CusF - - - 0.000000000000000000000000000000000000003132 147.0
PYH2_k127_6554644_0 Glutaminyl-tRNA synthetase K01886 - 6.1.1.18 0.0 1141.0
PYH2_k127_6554644_1 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007066 520.0
PYH2_k127_6554644_2 ErfK YbiS YcfS YnhG family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007189 372.0
PYH2_k127_6554644_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005387 299.0
PYH2_k127_6560520_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0 1140.0
PYH2_k127_6560520_1 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0 1103.0
PYH2_k127_6560520_2 Arginyl-tRNA synthetase K01887 - 6.1.1.19 3.779e-310 957.0
PYH2_k127_6560520_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 5.237e-269 830.0
PYH2_k127_6560520_4 Cobyrinic acid ac-diamide synthase K03496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 477.0
PYH2_k127_6560520_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 390.0
PYH2_k127_6560520_6 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 378.0
PYH2_k127_6560520_7 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008345 317.0
PYH2_k127_6563615_0 Heavy metal translocating P-type atpase K01533 - 3.6.3.4 0.0 1493.0
PYH2_k127_6563615_1 Cytochrome c oxidase accessory protein ccog - - - 1.531e-297 917.0
PYH2_k127_6563615_2 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 593.0
PYH2_k127_6563615_3 cytochrome c oxidase cbb3-type, subunit II K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002392 482.0
PYH2_k127_6563615_4 FixH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000433 479.0
PYH2_k127_6563615_5 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001217 265.0
PYH2_k127_6563615_6 Sigma-70, region 4 K03089 - - 0.000000000000000000000000000000000000007992 147.0
PYH2_k127_6563615_7 Cytochrome oxidase maturation protein - - - 0.000000000000000000000000004843 115.0
PYH2_k127_6563615_8 Cbb3-type cytochrome oxidase component FixQ - - - 0.0000000000000000000000001359 108.0
PYH2_k127_6567502_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 2.477e-251 778.0
PYH2_k127_6567502_1 auxin efflux carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 503.0
PYH2_k127_6567502_2 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.000000000000000000000000000000000000000000000000349 176.0
PYH2_k127_6577920_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 8.046e-221 686.0
PYH2_k127_6577920_1 Belongs to the pseudouridine synthase RsuA family K06183 - 5.4.99.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 462.0
PYH2_k127_6577920_2 COG2202 FOG PAS PAC domain K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 472.0
PYH2_k127_6577920_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007719 341.0
PYH2_k127_6577920_4 cytochrome c biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001773 252.0
PYH2_k127_6577920_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000000007632 189.0
PYH2_k127_6580511_0 type II secretion system protein E K02454,K02504,K02652,K12276 - - 0.0 1096.0
PYH2_k127_6580511_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 1.629e-269 832.0
PYH2_k127_6580511_10 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 482.0
PYH2_k127_6580511_11 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 378.0
PYH2_k127_6580511_12 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 359.0
PYH2_k127_6580511_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 336.0
PYH2_k127_6580511_14 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 317.0
PYH2_k127_6580511_15 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000664 280.0
PYH2_k127_6580511_16 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001611 244.0
PYH2_k127_6580511_17 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.0000000000000000000000000000000000000000000000000000000000000000002058 230.0
PYH2_k127_6580511_18 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000000000000000000002913 225.0
PYH2_k127_6580511_19 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.000000000000000000000000000000000000000000242 158.0
PYH2_k127_6580511_2 CBS domain containing protein - - - 8.325e-235 730.0
PYH2_k127_6580511_20 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000004 111.0
PYH2_k127_6580511_21 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.00000000000000004671 82.0
PYH2_k127_6580511_3 Type II secretion system K02653 - - 5.698e-233 724.0
PYH2_k127_6580511_4 Tyrosine recombinase xerD K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008948 571.0
PYH2_k127_6580511_5 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 564.0
PYH2_k127_6580511_6 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 543.0
PYH2_k127_6580511_7 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 546.0
PYH2_k127_6580511_8 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 503.0
PYH2_k127_6580511_9 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002134 493.0
PYH2_k127_6587655_0 AsmA family K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 604.0
PYH2_k127_6587655_1 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008359 499.0
PYH2_k127_6587655_2 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 430.0
PYH2_k127_6587655_3 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 428.0
PYH2_k127_6587655_4 nitroreductase K09019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 364.0
PYH2_k127_6587655_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003377 251.0
PYH2_k127_6587655_6 Transcriptional regulator K16137 - - 0.0000000000000000000000000000000000000000001678 158.0
PYH2_k127_6587655_7 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000000000000556 143.0
PYH2_k127_6587655_8 thiamine biosynthesis protein ThiS K03154 - - 0.000000000000000000000000000000008063 128.0
PYH2_k127_6595635_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 0.0 1659.0
PYH2_k127_6595635_1 Putative diguanylate phosphodiesterase - - - 0.0 1609.0
PYH2_k127_6595635_10 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 544.0
PYH2_k127_6595635_11 Belongs to the SAICAR synthetase family K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 518.0
PYH2_k127_6595635_12 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 423.0
PYH2_k127_6595635_13 Phosphoglycerate mutase family K02226 - 3.1.3.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004321 381.0
PYH2_k127_6595635_14 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 338.0
PYH2_k127_6595635_15 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 324.0
PYH2_k127_6595635_16 Protein of unknown function (DUF3025) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006221 325.0
PYH2_k127_6595635_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001529 269.0
PYH2_k127_6595635_19 Phosphate-starvation-inducible E K13256 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006729 244.0
PYH2_k127_6595635_2 von Willebrand factor, type A - - - 0.0 1524.0
PYH2_k127_6595635_20 Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000001758 239.0
PYH2_k127_6595635_21 - - - - 0.0000000000000000000000000000000000000000000000000000000000003033 211.0
PYH2_k127_6595635_3 Ribulose bisphosphate carboxylase large chain, catalytic domain K01601 - 4.1.1.39 6.732e-320 979.0
PYH2_k127_6595635_4 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 7.425e-290 891.0
PYH2_k127_6595635_5 Transcriptional regulator K21703 - - 2.727e-201 628.0
PYH2_k127_6595635_6 Chemotaxis sensory transducer K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 602.0
PYH2_k127_6595635_7 ketose-bisphosphate aldolase K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000561 587.0
PYH2_k127_6595635_8 Carboxysome Shell Carbonic Anhydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 578.0
PYH2_k127_6595635_9 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 561.0
PYH2_k127_6607747_0 Cytochrome c-type biogenesis protein K02200 - - 2.337e-223 697.0
PYH2_k127_6607747_1 subunit of a heme lyase K02200 - - 0.0000000000000000000000000000000000000005508 148.0
PYH2_k127_6607747_2 protein ubiquitination K15502,K15503 - - 0.00000002049 61.0
PYH2_k127_6613241_0 PFAM glycosyl transferase family 39 - - - 1.015e-251 780.0
PYH2_k127_6613241_1 Pfam Glycosyl transferase family 2 - - - 2.078e-206 646.0
PYH2_k127_6613241_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 3.288e-204 636.0
PYH2_k127_6613241_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005045 553.0
PYH2_k127_6613241_4 Smr protein MutS2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 312.0
PYH2_k127_6616388_0 Heparinase II/III-like protein - - - 0.0 1189.0
PYH2_k127_6616388_1 Sulfatase - - - 0.0 1030.0
PYH2_k127_6616388_10 Pfam Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000973 533.0
PYH2_k127_6616388_11 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 529.0
PYH2_k127_6616388_12 Glycosyltransferase WbsX - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 473.0
PYH2_k127_6616388_13 glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 393.0
PYH2_k127_6616388_14 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 373.0
PYH2_k127_6616388_15 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007836 372.0
PYH2_k127_6616388_16 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 342.0
PYH2_k127_6616388_17 Sulfotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007729 236.0
PYH2_k127_6616388_18 3-demethylubiquinone-9 3-O-methyltransferase activity K00568,K15257 - 2.1.1.222,2.1.1.64 0.00000000000000000000000000000000000000000000000000000000000001277 227.0
PYH2_k127_6616388_19 transferase activity, transferring glycosyl groups K00754 - - 0.00000000000000000000000000000000000000000002911 175.0
PYH2_k127_6616388_2 Asparagine synthase K01953 - 6.3.5.4 1.938e-287 885.0
PYH2_k127_6616388_20 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000006936 149.0
PYH2_k127_6616388_21 Formyl transferase - - - 0.000000000000000000000000000000000001225 149.0
PYH2_k127_6616388_22 Methyltransferase FkbM domain - - - 0.0000000000000000000000000000000001513 144.0
PYH2_k127_6616388_3 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 6.221e-278 869.0
PYH2_k127_6616388_4 Capsular polysaccharide biosynthesis protein CapK K01912 - 6.2.1.30 6.886e-261 814.0
PYH2_k127_6616388_5 PFAM Prenyltransferase squalene oxidase - - - 2.476e-250 776.0
PYH2_k127_6616388_6 Wzy family polymerase, exosortase system type 1 associated - - - 3.368e-238 741.0
PYH2_k127_6616388_7 - - - - 5.272e-209 654.0
PYH2_k127_6616388_8 Sulfotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000655 577.0
PYH2_k127_6616388_9 Glycosyl transferase 4-like domain K13668 - 2.4.1.346 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 544.0
PYH2_k127_661914_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1193.0
PYH2_k127_661914_1 serine threonine protein kinase - - - 6.463e-197 615.0
PYH2_k127_661914_2 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008669 582.0
PYH2_k127_661914_3 domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 520.0
PYH2_k127_661914_4 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006431 384.0
PYH2_k127_661914_5 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 379.0
PYH2_k127_661914_6 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000000000001093 135.0
PYH2_k127_6625534_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1150.0
PYH2_k127_6625534_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 7.76e-249 770.0
PYH2_k127_6625534_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 523.0
PYH2_k127_6625534_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003029 256.0
PYH2_k127_6625534_4 Domain of unknown function (DUF4845) - - - 0.00000000000000000000000000000000000000000000000000006611 189.0
PYH2_k127_6625534_5 Glutaredoxin-like domain (DUF836) K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000001052 162.0
PYH2_k127_6679889_0 PrpE from Ralstonia solanacearum can produce acetyl-, propionyl-, butyryl- and acrylyl-coenzyme A, and Salmonella enterica produces propionyl- and butyryl-coenzyme A K01908 - 6.2.1.17 0.0 1244.0
PYH2_k127_6679889_1 RESPONSE REGULATOR receiver - - - 0.0 1153.0
PYH2_k127_6679889_2 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 7.271e-276 854.0
PYH2_k127_6679889_3 PFAM AFG1-family ATPase K06916 - - 2.776e-209 654.0
PYH2_k127_6679889_4 Belongs to the methyltransferase superfamily K06969 - 2.1.1.191 8.092e-194 607.0
PYH2_k127_6679889_5 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 605.0
PYH2_k127_6679889_6 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 531.0
PYH2_k127_6679889_7 Dehydrogenase E1 component K00164 - 1.2.4.2 0.00000000000000000000000000000000000000000000000000000000000000001226 225.0
PYH2_k127_6679889_8 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000002169 132.0
PYH2_k127_6680130_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.0 1029.0
PYH2_k127_6680130_1 ATP synthase F1, epsilon subunit - - - 1.282e-266 830.0
PYH2_k127_6680130_10 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.000000000000000000000000000000000000000000000000000000000000000000000000005375 253.0
PYH2_k127_6680130_11 phosphocarrier protein Hpr K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000007812 164.0
PYH2_k127_6680130_2 glutamate--cysteine ligase K01919 - 6.3.2.2 1.623e-259 802.0
PYH2_k127_6680130_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.302e-246 762.0
PYH2_k127_6680130_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 6.877e-194 609.0
PYH2_k127_6680130_5 AmpG muropeptide MFS transporter K08218 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 603.0
PYH2_k127_6680130_6 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 565.0
PYH2_k127_6680130_7 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003246 408.0
PYH2_k127_6680130_8 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 395.0
PYH2_k127_6680130_9 COG2202 FOG PAS PAC domain K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006008 403.0
PYH2_k127_6705254_0 Dynamin family - - - 2.014e-222 691.0
PYH2_k127_6705254_1 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 535.0
PYH2_k127_6705254_2 Domain of unknown function (DUF4340) - - - 0.00000000000000000000000000000000000000000000000000000000000313 208.0
PYH2_k127_671465_0 Polyphosphate kinase 2 (PPK2) - - - 9.337e-275 849.0
PYH2_k127_671465_1 PFAM CHAD domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 530.0
PYH2_k127_671465_2 PLD-like domain - - - 0.0000000000000000000000000000000000000000000000000006893 184.0
PYH2_k127_6728829_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 0.0 1099.0
PYH2_k127_6728829_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 9.86e-282 867.0
PYH2_k127_6728829_10 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000000000000000000000000000000000006253 152.0
PYH2_k127_6728829_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 3.24e-256 790.0
PYH2_k127_6728829_3 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 593.0
PYH2_k127_6728829_4 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004451 563.0
PYH2_k127_6728829_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003245 397.0
PYH2_k127_6728829_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 396.0
PYH2_k127_6728829_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 329.0
PYH2_k127_6728829_8 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 314.0
PYH2_k127_6728829_9 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.000000000000000000000000000000000000000000000000000006623 190.0
PYH2_k127_6740102_0 ABC-type antimicrobial peptide transport system, permease component K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008802 565.0
PYH2_k127_6740102_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006401 545.0
PYH2_k127_6740102_2 Pfam ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005069 427.0
PYH2_k127_6740102_3 Catalyzes the synthesis of activated sulfate K00860 - 2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000883 320.0
PYH2_k127_6740102_4 Transport permease protein K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004988 271.0
PYH2_k127_6741709_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 0.0 1168.0
PYH2_k127_6741709_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 5.479e-312 957.0
PYH2_k127_6741709_10 DJ-1/PfpI family K05520 - 3.5.1.124 0.00000000000000000000000000000000000000000000000000000000000000000000007712 245.0
PYH2_k127_6741709_11 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000000000000000000000004236 197.0
PYH2_k127_6741709_12 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.00000000000000000000000000000000000000000000001739 173.0
PYH2_k127_6741709_13 An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH K00240,K09159 GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006105,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015980,GO:0016043,GO:0016999,GO:0017013,GO:0017144,GO:0018065,GO:0018293,GO:0019538,GO:0019752,GO:0022607,GO:0034552,GO:0034622,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0043648,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0045333,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072350,GO:1901564 1.3.5.1,1.3.5.4 0.00000000000000000000004964 102.0
PYH2_k127_6741709_2 Dehydrogenase E1 component K00164 - 1.2.4.2 1.781e-280 867.0
PYH2_k127_6741709_3 Belongs to the citrate synthase family K01647 - 2.3.3.1 3.77e-264 815.0
PYH2_k127_6741709_4 malic enzyme K00029 - 1.1.1.40 1.42e-242 757.0
PYH2_k127_6741709_5 Belongs to the citrate synthase family K01659 - 2.3.3.5 1.183e-237 736.0
PYH2_k127_6741709_6 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008876 538.0
PYH2_k127_6741709_7 TRANSCRIPTIONal REGULATOR, GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 483.0
PYH2_k127_6741709_8 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 478.0
PYH2_k127_6741709_9 ribosomal large subunit export from nucleus - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 282.0
PYH2_k127_6744249_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1488.0
PYH2_k127_6744249_1 Virulence factor BrkB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 353.0
PYH2_k127_6744249_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000008208 213.0
PYH2_k127_6744970_0 - - - - 8.678e-285 880.0
PYH2_k127_6744970_1 Outer membrane efflux protein - - - 1.127e-227 712.0
PYH2_k127_6744970_2 UPF0761 membrane protein K07058 - - 6.217e-207 649.0
PYH2_k127_6744970_3 PFAM pyridoxamine 5'-phosphate oxidase-related FMN-binding K07226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000455 385.0
PYH2_k127_6744970_4 Thioredoxin-like K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 319.0
PYH2_k127_6744970_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 289.0
PYH2_k127_6744970_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.0000000000000000000000000000000000003712 141.0
PYH2_k127_6752486_0 Diguanylate cyclase - - - 0.0 1050.0
PYH2_k127_6752486_1 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 589.0
PYH2_k127_6752486_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004639 521.0
PYH2_k127_6752486_3 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 477.0
PYH2_k127_6752486_4 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005223 386.0
PYH2_k127_6752486_5 arsenate reductase K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000001092 218.0
PYH2_k127_6752486_6 fad dependent oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000008503 202.0
PYH2_k127_6752486_7 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000000001837 154.0
PYH2_k127_6752486_8 Regulatory protein, FmdB family - - - 0.000000000000000000000000000000002829 130.0
PYH2_k127_6757573_0 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 4.678e-212 660.0
PYH2_k127_6757573_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003433 542.0
PYH2_k127_6757573_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 491.0
PYH2_k127_6757573_3 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 439.0
PYH2_k127_6757573_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 415.0
PYH2_k127_6757573_5 Mota tolq exbb proton channel K03561 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 371.0
PYH2_k127_6757573_6 Biopolymer transport protein K03559 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007191 248.0
PYH2_k127_6757573_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000001151 228.0
PYH2_k127_6757573_8 Trm112p-like protein K09791 - - 0.0000000000000007925 78.0
PYH2_k127_6763137_0 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 2.04e-215 670.0
PYH2_k127_6763137_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 455.0
PYH2_k127_6763137_2 Bacterial type II and III secretion system protein - - - 0.0000000000000000000000000000000000000001704 152.0
PYH2_k127_6763344_0 Belongs to the MurCDEF family K03802 - 6.3.2.29,6.3.2.30 0.0 1591.0
PYH2_k127_6763344_1 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147 - - 0.0 1434.0
PYH2_k127_6763344_10 Domain of unknown function (DUF1854) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003177 273.0
PYH2_k127_6763344_11 tol-pal system-associated acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000272 261.0
PYH2_k127_6763344_13 Pfam Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004725 240.0
PYH2_k127_6763344_14 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - GO:0005575,GO:0005623,GO:0008150,GO:0009987,GO:0016043,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043933,GO:0044085,GO:0044464,GO:0051259,GO:0051260,GO:0051301,GO:0065003,GO:0071840 - 0.000000000000001629 86.0
PYH2_k127_6763344_2 cyanophycin synthetase K03802 - 6.3.2.29,6.3.2.30 0.0 1283.0
PYH2_k127_6763344_3 Involved in the tonB-independent uptake of proteins K03641 - - 1.324e-261 809.0
PYH2_k127_6763344_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 461.0
PYH2_k127_6763344_5 Mota tolq exbb proton channel K03562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 428.0
PYH2_k127_6763344_6 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008144,GO:0016829,GO:0016840,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0051536,GO:0051539,GO:0051540,GO:1901681,GO:1904047 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 417.0
PYH2_k127_6763344_7 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008591 403.0
PYH2_k127_6763344_8 Cell division and transport-associated protein TolA K03646 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003263 365.0
PYH2_k127_6763344_9 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 319.0
PYH2_k127_6769602_0 pyridine - - - 8.898e-273 841.0
PYH2_k127_6769602_1 Part of the ABC transporter complex NodIJ involved in the export of the nodulation factors (Nod factors), the bacterial signal molecules that induce symbiosis and subsequent nodulation induction. Nod factors are LCO (lipo-chitin oligosaccharide), a modified beta-1,4-linked N-acetylglucosamine oligosaccharide. This subunit is responsible for energy coupling to the transport system K01990,K09695 - - 5.072e-194 605.0
PYH2_k127_6769602_2 Transport permease protein K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 492.0
PYH2_k127_6769602_3 Ankyrin repeats (many copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 282.0
PYH2_k127_6769602_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001435 270.0
PYH2_k127_6769602_5 Serine aminopeptidase, S33 K07018 - - 0.000000000000000000000000000000000000000000000000000000000000000002207 232.0
PYH2_k127_6769602_6 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000002958 194.0
PYH2_k127_6769602_7 Transcriptional regulator - - - 0.00000000000000000000000000000000004084 134.0
PYH2_k127_6769602_8 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000002062 104.0
PYH2_k127_6787574_0 Histidine kinase - - - 0.0 1229.0
PYH2_k127_6787574_1 response regulator K02481,K10941 - - 3.766e-260 806.0
PYH2_k127_6787574_2 Sugar transferase K21303 - 2.7.8.40 2.138e-252 783.0
PYH2_k127_6787574_3 peptidase S1 and S6, chymotrypsin Hap - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004045 462.0
PYH2_k127_6787574_4 UDP binding domain K02474 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 447.0
PYH2_k127_6787574_5 Asparagine synthase K01953 - 6.3.5.4 0.0000007588 51.0
PYH2_k127_6805898_0 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 365.0
PYH2_k127_6805898_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000009535 249.0
PYH2_k127_6805898_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000002316 242.0
PYH2_k127_6806842_0 Diguanylate cyclase - - - 0.0 1209.0
PYH2_k127_6806842_1 HDOD domain - - - 0.0 1206.0
PYH2_k127_6806842_10 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000000000000001556 207.0
PYH2_k127_6806842_11 - - - - 0.0000000000000000000000000000000000000000163 161.0
PYH2_k127_6806842_12 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000003956 104.0
PYH2_k127_6806842_13 Domain of unknown function (DUF4124) - - - 0.000000000000003721 83.0
PYH2_k127_6806842_2 transporter component K07112 - - 1.559e-237 746.0
PYH2_k127_6806842_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 8.051e-228 708.0
PYH2_k127_6806842_4 Belongs to the aconitase IPM isomerase family K01682 - 4.2.1.3,4.2.1.99 5.297e-221 686.0
PYH2_k127_6806842_5 Histidine Phosphotransfer domain - - - 2.291e-220 685.0
PYH2_k127_6806842_6 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 396.0
PYH2_k127_6806842_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 394.0
PYH2_k127_6806842_8 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 296.0
PYH2_k127_6806842_9 Glutaredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000005795 235.0
PYH2_k127_682286_0 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009337 500.0
PYH2_k127_682286_1 histidine kinase A domain protein K07679 - 2.7.13.3 0.0000000000000000000000000007803 119.0
PYH2_k127_682286_2 Histidine kinase - - - 0.000000000000000000002582 106.0
PYH2_k127_682286_3 Bacterial extracellular solute-binding proteins, family 3 K02030 - - 0.000000000000004388 85.0
PYH2_k127_682286_4 family 3 K02030 - - 0.0001119 53.0
PYH2_k127_6846290_0 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.0 1097.0
PYH2_k127_6846290_1 The M ring may be actively involved in energy transduction K02409 - - 5.346e-316 971.0
PYH2_k127_6846290_10 VacJ family lipoprotein K04754 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 444.0
PYH2_k127_6846290_11 Plays an important role in bacterial chemotaxis signal transduction pathway by accelerating the dephosphorylation of phosphorylated CheY (CheY-P) K03414 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009857 423.0
PYH2_k127_6846290_12 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006392 311.0
PYH2_k127_6846290_13 Response regulator receiver K03413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002652 248.0
PYH2_k127_6846290_14 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009693 243.0
PYH2_k127_6846290_15 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000000000000002548 215.0
PYH2_k127_6846290_16 Flagellar hook-basal body complex protein FliE K02408 - - 0.0000000000000000000000000000000000000000000000000001247 187.0
PYH2_k127_6846290_17 PFAM Flagellar assembly protein FliH Type III secretion system HrpE K02411 - - 0.0000000000000000000000000000000000000000000000000001701 192.0
PYH2_k127_6846290_18 Tfp pilus assembly protein FimV - - - 0.000000000000000000000000000000000000000000000000008249 183.0
PYH2_k127_6846290_2 response regulator K10943 - - 7.668e-265 819.0
PYH2_k127_6846290_3 PFAM EAL domain protein - - - 2.484e-239 745.0
PYH2_k127_6846290_4 signal transduction histidine kinase K10942 - 2.7.13.3 4.753e-217 679.0
PYH2_k127_6846290_5 ATP synthase alpha/beta family, nucleotide-binding domain K02412 - 3.6.3.14 7.769e-210 661.0
PYH2_k127_6846290_6 Response regulator receiver K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005333 592.0
PYH2_k127_6846290_7 Response regulator receiver K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 585.0
PYH2_k127_6846290_8 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 510.0
PYH2_k127_6846290_9 flagellar motor switch protein K02410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 475.0
PYH2_k127_6849436_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.0 1375.0
PYH2_k127_6849436_1 Belongs to the peptidase M17 family K01255 - 3.4.11.1 7.833e-292 898.0
PYH2_k127_6849436_2 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 - 1.2.4.1 1.113e-283 876.0
PYH2_k127_6849436_3 Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 561.0
PYH2_k127_6849436_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000002799 89.0
PYH2_k127_6849436_5 - - - - 0.00000000000000001329 87.0
PYH2_k127_6849674_0 Putative transposase - - - 9.979e-195 614.0
PYH2_k127_6849674_1 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 423.0
PYH2_k127_6849674_2 phage integrase domain protein SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003415 258.0
PYH2_k127_6849674_3 Transposase - - - 0.0000000000000000000000000000000000006069 144.0
PYH2_k127_6849674_4 Putative transposase - - - 0.000000000000342 71.0
PYH2_k127_6849674_5 Putative transposase - - - 0.0006339 46.0
PYH2_k127_6850083_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 1.777e-217 677.0
PYH2_k127_6850083_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004642 259.0
PYH2_k127_6880599_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0 1464.0
PYH2_k127_6880599_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1349.0
PYH2_k127_6880599_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1262.0
PYH2_k127_6880599_3 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 448.0
PYH2_k127_6880599_4 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 370.0
PYH2_k127_6880599_6 Protein of unknown function (DUF3568) - - - 0.00000000000000000000000001983 113.0
PYH2_k127_6880599_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000002604 52.0
PYH2_k127_6882312_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 0.0 1187.0
PYH2_k127_6882312_1 Cell shape determining protein, MreB Mrl family K03569 - - 4.651e-217 674.0
PYH2_k127_6882312_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007955 552.0
PYH2_k127_6882312_3 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 515.0
PYH2_k127_6882312_4 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 479.0
PYH2_k127_6882312_5 Rod shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 330.0
PYH2_k127_6882312_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000004173 173.0
PYH2_k127_6906809_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.547e-271 837.0
PYH2_k127_6906809_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 3.855e-267 827.0
PYH2_k127_6906809_2 Lytic murein transglycosylase B K08305 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 537.0
PYH2_k127_6906809_3 phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002186 329.0
PYH2_k127_6906809_4 Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum K13626 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009835 270.0
PYH2_k127_6906809_5 Chemoreceptor zinc-binding domain - - - 0.0000000000000000000000000000000000000000000000000001304 189.0
PYH2_k127_6906809_6 - - - - 0.00000000000000000000000000000000000000003801 153.0
PYH2_k127_6906809_7 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 0.00000000000000000000000000000000000000007716 151.0
PYH2_k127_6908368_0 Metal-dependent hydrolase HDOD - - - 1.345e-279 864.0
PYH2_k127_6908368_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 1.15e-219 683.0
PYH2_k127_6908368_2 PFAM OmpA MotB domain protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 572.0
PYH2_k127_6908368_3 MotA/TolQ/ExbB proton channel family K02556 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 458.0
PYH2_k127_6908368_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 333.0
PYH2_k127_6908368_5 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007732 274.0
PYH2_k127_6908368_6 tRNA (guanine-N7-)-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000004167 227.0
PYH2_k127_6908368_7 Glycosyl transferases group 1 - - - 0.0000000000000000000000002078 108.0
PYH2_k127_6973608_0 Helicase K03657 - 3.6.4.12 0.0 1357.0
PYH2_k127_6973608_1 acetyl-CoA hydrolase K18288 - - 0.0 1146.0
PYH2_k127_6973608_2 Phosphoribulokinase K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 597.0
PYH2_k127_6973608_3 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003372 347.0
PYH2_k127_6973608_4 Mo-molybdopterin cofactor metabolic process K03636,K21142 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0071704,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.8.1.12 0.0000000000000000000000000000000000000001068 151.0
PYH2_k127_6991832_0 Peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 311.0
PYH2_k127_6991832_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 301.0
PYH2_k127_6991832_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002822 274.0
PYH2_k127_6991832_3 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000757 246.0
PYH2_k127_7001224_0 Chemotaxis K13924 - 2.1.1.80,3.1.1.61 0.0 1256.0
PYH2_k127_7003482_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 1.117e-269 831.0
PYH2_k127_7003482_1 - - - - 0.00000000000000000000000000000000000000000000000001709 180.0
PYH2_k127_7003482_2 - - - - 0.00000000000000000000000000000000000008225 148.0
PYH2_k127_7033816_0 Recombinase zinc beta ribbon domain K06400 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005784 554.0
PYH2_k127_7033816_1 Ribbon-helix-helix protein, copG family - - - 0.0000000000000001988 83.0
PYH2_k127_7039523_0 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 382.0
PYH2_k127_7039523_1 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000002451 147.0
PYH2_k127_7076777_0 PFAM CHASE2 domain - - - 0.0 1011.0
PYH2_k127_7076777_1 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008576 516.0
PYH2_k127_7076777_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 361.0
PYH2_k127_7076777_3 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008657 345.0
PYH2_k127_7076777_4 Bacterial SH3 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 286.0
PYH2_k127_7076777_5 chain release factor K15034 - - 0.0000000000000000000000000000000000000000000000000000000000000000001639 232.0
PYH2_k127_7076777_7 Pfam Nitroreductase - - - 0.0000000000000000000000000000000000000000000000002477 176.0
PYH2_k127_7076777_8 ABC transporter transmembrane region K06148 - - 0.0000000000000000000000000000000000000000000000004404 177.0
PYH2_k127_7076777_9 - - - - 0.00000000000000000000000000000000004306 143.0
PYH2_k127_7080793_0 D-Amino acid dehydrogenase K00285,K03153 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016491,GO:0016638,GO:0016641,GO:0017144,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0036094,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043168,GO:0043436,GO:0043799,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0071949,GO:0072527,GO:0072528,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.4.3.19,1.4.5.1 6.259e-195 611.0
PYH2_k127_7080793_1 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 360.0
PYH2_k127_7080793_2 Belongs to the Fur family K09826 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 283.0
PYH2_k127_7080793_3 type 4 fimbrial biogenesis K02672 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003821 280.0
PYH2_k127_7080793_4 Neisseria PilC beta-propeller domain K02674 - - 0.0000000000000000000000000000000000000000000000000000000000002977 221.0
PYH2_k127_7080793_5 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000000000000000000000000006926 182.0
PYH2_k127_7080793_6 Prokaryotic N-terminal methylation motif K02655 - - 0.0000000000000000000000000000000000000001005 154.0
PYH2_k127_7080793_7 Tfp pilus assembly protein - - - 0.0000000000000000000000000000000001121 138.0
PYH2_k127_7080793_8 Pilus assembly protein PilX - - - 0.00000000000000000000000000000000018 137.0
PYH2_k127_7112482_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.556e-226 704.0
PYH2_k127_7112482_1 cytochrome oxidase assembly K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 585.0
PYH2_k127_7112482_2 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009509 534.0
PYH2_k127_7112482_3 CRP FNR family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 408.0
PYH2_k127_7112482_4 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 366.0
PYH2_k127_7112482_5 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 319.0
PYH2_k127_7254846_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 445.0
PYH2_k127_7254846_1 17 kDa surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 297.0
PYH2_k127_7254846_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.00000000000000000000000000000000000000009582 150.0
PYH2_k127_7254846_3 ABC transporter, substrate-binding protein, aliphatic K02051 - - 0.0000002081 63.0
PYH2_k127_7298511_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.94e-299 927.0
PYH2_k127_7298511_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.458e-198 619.0
PYH2_k127_7298511_2 COG2202 FOG PAS PAC domain K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 305.0
PYH2_k127_7311925_0 - - - - 0.00000000000000000000000000000000000002339 150.0
PYH2_k127_7311925_1 PFAM Transposase, IS4-like - - - 0.0000000000006812 72.0
PYH2_k127_7311925_2 ADP-glyceromanno-heptose 6-epimerase activity K01784,K10817,K12443,K15672 - 2.3.1.94,5.1.3.2 0.00000005093 59.0
PYH2_k127_7335871_0 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 422.0
PYH2_k127_7335871_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 331.0
PYH2_k127_7335871_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 301.0
PYH2_k127_7350260_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 402.0
PYH2_k127_7350260_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 293.0
PYH2_k127_7350260_2 NosL - - - 0.000000000000000000000000000000000000000000000000118 180.0
PYH2_k127_7430700_0 oxidoreductase FAD NAD(P)-binding domain protein - - - 1.469e-299 922.0
PYH2_k127_7430700_1 Diguanylate cyclase K02488 - 2.7.7.65 7.334e-225 698.0
PYH2_k127_7430700_2 SseB protein N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001059 252.0
PYH2_k127_7430700_3 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.000000000000000000000000000000000000000008986 153.0
PYH2_k127_7430700_4 - - - - 0.000000000000000000000000000000002269 130.0
PYH2_k127_7430700_5 DsrC like protein K11179 - - 0.0000000000000000000000001509 107.0
PYH2_k127_7486586_0 HflC and HflK could encode or regulate a protease K04088 - - 6.87e-230 715.0
PYH2_k127_7486586_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 1.186e-226 704.0
PYH2_k127_7486586_2 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 537.0
PYH2_k127_7486586_3 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006177 488.0
PYH2_k127_7486586_4 protein conserved in bacteria K09937 - - 0.000000000000000000000000002857 111.0
PYH2_k127_7503918_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 8.983e-197 624.0
PYH2_k127_7503918_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 552.0
PYH2_k127_7503918_2 Peptidase family S51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
PYH2_k127_7503918_3 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000000000000000000005284 124.0
PYH2_k127_7506330_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 1.279e-309 970.0
PYH2_k127_7506330_1 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009427 518.0
PYH2_k127_7519179_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 488.0
PYH2_k127_7519179_1 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 483.0
PYH2_k127_7519179_2 phosphoribosyltransferase K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 342.0
PYH2_k127_7519179_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.0000000000000000000000000000000000000000000000000000000000000000001322 233.0
PYH2_k127_7529035_0 Protein of unknown function - - - 0.0 2321.0
PYH2_k127_7529035_1 peptidase U62, modulator of DNA gyrase K03568 - - 1.161e-311 956.0
PYH2_k127_7529035_2 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 561.0
PYH2_k127_7529035_3 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 557.0
PYH2_k127_7529035_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 505.0
PYH2_k127_7529035_5 part of a sulfur-relay system K11179 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0097163,GO:0140104,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 444.0
PYH2_k127_7529035_6 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009324 274.0
PYH2_k127_7555553_0 Histidine kinase - - - 0.0 1388.0
PYH2_k127_7555553_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1334.0
PYH2_k127_7555553_10 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000000000000000000000009743 164.0
PYH2_k127_7555553_12 - - - - 0.000004449 53.0
PYH2_k127_7555553_2 peptidylprolyl isomerase K03770 - 5.2.1.8 0.0 1051.0
PYH2_k127_7555553_3 Diguanylate cyclase - - - 4.4e-224 715.0
PYH2_k127_7555553_4 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 499.0
PYH2_k127_7555553_5 Histidine kinase K03413,K13040 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 348.0
PYH2_k127_7555553_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000002454 236.0
PYH2_k127_7555553_7 - - - - 0.000000000000000000000000000000000000000000000000000000000033 209.0
PYH2_k127_7555553_8 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000004367 191.0
PYH2_k127_7555553_9 PFAM NLP P60 protein - - - 0.00000000000000000000000000000000000000000000004778 174.0
PYH2_k127_7564622_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07239,K15726 - - 0.0 1807.0
PYH2_k127_7564622_1 Outer membrane efflux protein - - - 2.88e-223 700.0
PYH2_k127_7564622_2 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003142 519.0
PYH2_k127_7564622_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009151 447.0
PYH2_k127_7564622_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000608 343.0
PYH2_k127_7564622_5 Protein of unknown function (DUF3240) - - - 0.00000000000000000000000000000000000000000000000000000008733 195.0
PYH2_k127_7564622_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000009899 68.0
PYH2_k127_7567942_0 helix_turn_helix, Lux Regulon K03556 - - 6.735e-216 685.0
PYH2_k127_7585701_0 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 554.0
PYH2_k127_7585701_1 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 291.0
PYH2_k127_7585701_2 mRNA catabolic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006287 243.0
PYH2_k127_7585701_3 3-demethylubiquinone-9 3-methyltransferase - - - 0.000000000000000002428 85.0
PYH2_k127_7606438_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0 1057.0
PYH2_k127_7606438_1 chemotaxis K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 529.0
PYH2_k127_7606438_2 NADH ubiquinone oxidoreductase K18006 - 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 329.0
PYH2_k127_7609814_0 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 2.462e-250 775.0
PYH2_k127_7609814_1 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 552.0
PYH2_k127_7609814_2 Sporulation related domain K03749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 324.0
PYH2_k127_7609814_3 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component K11689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 310.0
PYH2_k127_7609814_4 - - - - 0.0000000000000000000000000000000000000000000000000000003227 194.0
PYH2_k127_7609814_5 TIGRFAM TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000001181 107.0
PYH2_k127_7609814_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000003588 85.0
PYH2_k127_7644067_0 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 493.0
PYH2_k127_7644405_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 5e-321 987.0
PYH2_k127_7644405_1 twitching motility protein K02670 - - 1.261e-233 725.0
PYH2_k127_7644405_2 twitching motility protein K02669,K12203 - - 5.444e-218 680.0
PYH2_k127_7644405_3 Redoxin domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 335.0
PYH2_k127_7644405_4 COG2202 FOG PAS PAC domain K03776 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006771 320.0
PYH2_k127_7644405_5 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009264 264.0
PYH2_k127_7644405_6 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000007452 224.0
PYH2_k127_7649715_0 Transposase DDE domain group 1 - - - 0.0000000000000000000000005475 111.0
PYH2_k127_7649715_1 PFAM PQQ enzyme repeat - - - 0.0000192 56.0
PYH2_k127_76651_0 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0 1056.0
PYH2_k127_76651_1 cytochrome complex assembly K02200 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002332 392.0
PYH2_k127_76651_2 DNA alkylation repair - - - 0.000000000000000000000000001618 112.0
PYH2_k127_7667847_0 photosynthesis K00575,K02453,K02656,K20543 - 2.1.1.80 0.0 1035.0
PYH2_k127_7667847_1 General secretory system II protein E domain protein K02454,K02652,K12276 - - 4.083e-254 792.0
PYH2_k127_7667847_2 HD domain - - - 4.835e-224 706.0
PYH2_k127_7667847_3 Glycosyl transferase family 41 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 625.0
PYH2_k127_7667847_4 Glycosyltransferase like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 458.0
PYH2_k127_7667847_5 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000000000000000000000000000000000000000000006415 199.0
PYH2_k127_76755_0 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 468.0
PYH2_k127_7731416_0 phospho-2-dehydro-3-deoxyheptonate aldolase K03856 - 2.5.1.54 2.915e-210 654.0
PYH2_k127_7731416_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005993 556.0
PYH2_k127_7731416_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 483.0
PYH2_k127_7731416_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004653 267.0
PYH2_k127_7736282_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004096 456.0
PYH2_k127_7736282_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 424.0
PYH2_k127_7736282_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 240.0
PYH2_k127_7762959_0 Aminotransferase K01845 - 5.4.3.8 7.909e-251 776.0
PYH2_k127_7762959_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004021 525.0
PYH2_k127_7762959_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 357.0
PYH2_k127_7762959_3 PFAM CheW domain protein K02659 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 339.0
PYH2_k127_7762959_4 chemotaxis K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 327.0
PYH2_k127_7762959_5 RESPONSE REGULATOR receiver K02657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003447 257.0
PYH2_k127_7762959_6 RESPONSE REGULATOR receiver K02658 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001534 243.0
PYH2_k127_7781577_0 sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 546.0
PYH2_k127_7781577_1 Cas6 Crispr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 405.0
PYH2_k127_7781577_2 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000000000000000000000000000003029 221.0
PYH2_k127_7781577_3 - - - - 0.000000000000000000000000000000000000001472 147.0
PYH2_k127_7781577_4 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.000000000000000000000000003575 110.0
PYH2_k127_7781577_5 - - - - 0.000000000000000000004727 94.0
PYH2_k127_7783723_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006148 605.0
PYH2_k127_7783723_1 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009124 453.0
PYH2_k127_7793716_0 PFAM glycosyl transferase, family 51 - - - 0.0 1798.0
PYH2_k127_7798515_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 8.384e-220 687.0
PYH2_k127_7798515_1 CNP1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001529 259.0
PYH2_k127_7798515_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000009327 168.0
PYH2_k127_7803210_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18303 - - 0.0 1888.0
PYH2_k127_7803210_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1639.0
PYH2_k127_7803210_10 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 503.0
PYH2_k127_7803210_11 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007015 447.0
PYH2_k127_7803210_12 Pfam Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006195 413.0
PYH2_k127_7803210_13 Binding-protein-dependent transport system inner membrane component K11070 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005834 383.0
PYH2_k127_7803210_14 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 322.0
PYH2_k127_7803210_15 protein conserved in bacteria K09921 - - 0.000000000000000000000000000000000000000000000000000000002056 201.0
PYH2_k127_7803210_16 - - - - 0.000000000000000000000000000000000000000000000000000009485 190.0
PYH2_k127_7803210_17 coa-binding K06929 - - 0.000000000000000000000000000000000000000000000000000163 189.0
PYH2_k127_7803210_18 PFAM HI0933 family protein K07007 - - 0.000000000000000000000000000000000000000000000002668 174.0
PYH2_k127_7803210_19 PEP-CTERM motif - - - 0.00000000000000000000000000000000002056 143.0
PYH2_k127_7803210_2 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 2.544e-247 771.0
PYH2_k127_7803210_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 4.95e-243 754.0
PYH2_k127_7803210_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006911 596.0
PYH2_k127_7803210_5 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008247 579.0
PYH2_k127_7803210_6 Diguanylate cyclase (GGDEF) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000977 591.0
PYH2_k127_7803210_7 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 553.0
PYH2_k127_7803210_8 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 557.0
PYH2_k127_7803210_9 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 528.0
PYH2_k127_7817379_0 Helicase K03722 - 3.6.4.12 1.012e-297 914.0
PYH2_k127_7817379_1 Peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 417.0
PYH2_k127_7817379_2 HIRAN - - - 0.00000000000000000000000000000000000000000000000000000003516 198.0
PYH2_k127_7817379_3 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.0000000000000000000000000000000009409 130.0
PYH2_k127_7829048_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 2.803e-223 698.0
PYH2_k127_7829048_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 407.0
PYH2_k127_7829048_2 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008387 271.0
PYH2_k127_7829048_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0009898,GO:0015886,GO:0016020,GO:0031224,GO:0031226,GO:0031235,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0071702,GO:0071705,GO:0071944,GO:0098552,GO:0098562,GO:1901678 - 0.00000000004904 66.0
PYH2_k127_7832267_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 1.521e-266 821.0
PYH2_k127_7832267_1 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 601.0
PYH2_k127_7832267_2 Anthranilate synthase K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 500.0
PYH2_k127_7832267_3 PFAM Aminotransferase, class IV K02619 - 4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 486.0
PYH2_k127_7832267_4 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000000000000001021 147.0
PYH2_k127_792045_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001794 257.0
PYH2_k127_8017141_0 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1793.0
PYH2_k127_8017141_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1065.0
PYH2_k127_8017141_2 PFAM pentapeptide repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 417.0
PYH2_k127_8017141_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 363.0
PYH2_k127_801904_0 Abc transporter K15738 - - 3.466e-297 914.0
PYH2_k127_801904_1 Periplasmic copper-binding K07218 - - 1.984e-231 720.0
PYH2_k127_801904_2 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 4.245e-219 681.0
PYH2_k127_801904_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002954 548.0
PYH2_k127_801904_4 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 522.0
PYH2_k127_801904_5 LemA Family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 340.0
PYH2_k127_801904_6 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.00000000000000000000000000000000000000000000000001198 185.0
PYH2_k127_801904_7 HI0933 family K07007 - - 0.0000000000000000000000000000000000000006498 147.0
PYH2_k127_8026659_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 524.0
PYH2_k127_8026659_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003137 236.0
PYH2_k127_8169288_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.764e-275 848.0
PYH2_k127_8169288_1 Zinc iron permease K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 490.0
PYH2_k127_8169288_2 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 420.0
PYH2_k127_8169288_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002728 264.0
PYH2_k127_8169288_5 - - - - 0.0000000000000000000000000000000000000000000000007239 175.0
PYH2_k127_8169288_6 Heavy metal-associated domain protein K07213 - - 0.00000000000000000000000000155 115.0
PYH2_k127_8169288_7 Histidine kinase K07638 - 2.7.13.3 0.0000000000000008131 77.0
PYH2_k127_8169288_8 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000001275 68.0
PYH2_k127_8182475_0 histidine kinase A domain protein K07679 - 2.7.13.3 3.916e-200 656.0
PYH2_k127_8182475_1 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain K07814 - - 0.00000000000000000004149 92.0
PYH2_k127_8210462_0 Molydopterin dinucleotide binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 571.0
PYH2_k127_8210462_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007348 498.0
PYH2_k127_8210462_2 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007512 347.0
PYH2_k127_8210462_3 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000001681 173.0
PYH2_k127_8210462_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000001535 138.0
PYH2_k127_8210462_5 Cytochrome c - - - 0.000000000000000000000001056 116.0
PYH2_k127_8210462_6 Protein of unknown function (DUF3341) - - - 0.0000000000000000000001286 106.0
PYH2_k127_8210462_7 leucine-zipper of insertion element IS481 - - - 0.000000001131 70.0
PYH2_k127_8210462_8 Glucose / Sorbosone dehydrogenase - - - 0.0000003532 62.0
PYH2_k127_8234969_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 340.0
PYH2_k127_8234969_2 NMT1-like family - - - 0.0000000000000000000000000000000000000000000001453 172.0
PYH2_k127_8234969_5 Helix-turn-helix type 11 - - - 0.00000000000000000000000000157 112.0
PYH2_k127_8254391_0 Domain of unknown function (DUF5127) - - - 2.857e-261 820.0
PYH2_k127_8254391_1 arylsulfatase A - - - 2.428e-232 726.0
PYH2_k127_8254391_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 306.0
PYH2_k127_8272135_0 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008837 555.0
PYH2_k127_8272135_1 Belongs to the DEAD box helicase family K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 368.0
PYH2_k127_8272135_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000291 241.0
PYH2_k127_8305931_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 3.143e-296 911.0
PYH2_k127_8305931_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 557.0
PYH2_k127_8305931_2 - - - - 0.00000000000000000000000000000000000000000000002203 173.0
PYH2_k127_8328078_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1047.0
PYH2_k127_8328078_1 PFAM ABC-1 domain protein K03688 - - 0.0 1045.0
PYH2_k127_8328078_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 375.0
PYH2_k127_8333001_0 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005743 482.0
PYH2_k127_8333001_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 320.0
PYH2_k127_8333001_2 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000000000000000000000000000000000000000004722 206.0
PYH2_k127_8344592_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.078e-226 712.0
PYH2_k127_8344592_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 555.0
PYH2_k127_8344592_2 Malonate decarboxylase, alpha subunit, transporter K13929 - 2.3.1.187 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 303.0
PYH2_k127_8344592_3 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000002182 233.0
PYH2_k127_8344592_4 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000000009503 222.0
PYH2_k127_8382786_0 protein conserved in bacteria K09919 - - 6.567e-239 739.0
PYH2_k127_8382786_1 Belongs to the UPF0061 (SELO) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003846 577.0
PYH2_k127_8434167_0 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001439 241.0
PYH2_k127_8434167_1 Alpha beta - - - 0.0000000000000000000000000000000000000000000000005461 189.0
PYH2_k127_8434167_2 Domain of unknown function (DUF4386) - - - 0.0000000000000000000000000000000000000000000001228 175.0
PYH2_k127_8436995_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.0 1058.0
PYH2_k127_8436995_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 5.859e-278 859.0
PYH2_k127_8436995_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929,K15792 - 6.3.2.10,6.3.2.13 3.087e-257 799.0
PYH2_k127_8436995_3 - - - - 5.379e-210 655.0
PYH2_k127_8436995_4 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 580.0
PYH2_k127_8436995_5 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 301.0
PYH2_k127_8436995_6 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 297.0
PYH2_k127_8436995_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000000000000000000000000000000000000000000009553 163.0
PYH2_k127_8436995_9 - - - - 0.00000009362 55.0
PYH2_k127_8446663_0 Cytochrome d1, heme K15864 - 1.7.2.1,1.7.99.1 0.0 1010.0
PYH2_k127_8446663_1 cytochrome d1, heme region K19345 - - 2.567e-250 773.0
PYH2_k127_8446663_10 blue (type 1) copper - - - 0.00000000000000000000000000000000000000000003344 162.0
PYH2_k127_8446663_11 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.000000000000000000000000000000000000003242 149.0
PYH2_k127_8446663_12 NapD protein K02570 - - 0.00000000000000000000000000002342 119.0
PYH2_k127_8446663_13 Flagellar Assembly Protein A K09749 - - 0.00000000000000002212 90.0
PYH2_k127_8446663_2 COG1522 Transcriptional regulators - - - 6.399e-208 649.0
PYH2_k127_8446663_3 4Fe-4S dicluster domain K02573 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 560.0
PYH2_k127_8446663_4 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 527.0
PYH2_k127_8446663_5 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 519.0
PYH2_k127_8446663_6 cytochrome c-type protein K02569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 394.0
PYH2_k127_8446663_7 Pfam cytochrome c K17230 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 357.0
PYH2_k127_8446663_8 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005276 273.0
PYH2_k127_8446663_9 transcriptional regulator AsnC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002264 261.0
PYH2_k127_8464604_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 8.336e-250 774.0
PYH2_k127_8464604_1 phosphate-selective porin O and P - - - 1.519e-249 775.0
PYH2_k127_8464604_10 protein conserved in bacteria K09921 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 300.0
PYH2_k127_8464604_12 - - - - 0.000000000000000000000000000000000006218 141.0
PYH2_k127_8464604_2 Pfam Major Facilitator Superfamily - - - 6.097e-240 745.0
PYH2_k127_8464604_3 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 594.0
PYH2_k127_8464604_4 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003553 580.0
PYH2_k127_8464604_5 Periplasmic solute binding protein K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005852 557.0
PYH2_k127_8464604_6 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018,K00058 - 1.1.1.29,1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 551.0
PYH2_k127_8464604_7 Belongs to the glycerate kinase type-1 family K00865 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 458.0
PYH2_k127_8464604_8 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 449.0
PYH2_k127_8464604_9 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009202 351.0
PYH2_k127_8486826_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.0 1180.0
PYH2_k127_8486826_1 transglycosylase K08307 - - 3.208e-298 922.0
PYH2_k127_8486826_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002564 468.0
PYH2_k127_8486826_3 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 422.0
PYH2_k127_8486826_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 312.0
PYH2_k127_8489555_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 431.0
PYH2_k127_8489555_1 Protein of unknown function (DUF1109) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008171 384.0
PYH2_k127_8489555_2 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 325.0
PYH2_k127_8489555_3 - - - - 0.00000000000000000000000000000000000000000000000000003004 189.0
PYH2_k127_8489555_4 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.00000000000000000000000000000000000000000000000000006327 190.0
PYH2_k127_8489555_5 Putative quorum-sensing-regulated virulence factor K09954 - - 0.0000000000000000000000000000000000001199 141.0
PYH2_k127_8489555_6 - - - - 0.0000000000000004062 82.0
PYH2_k127_8489555_7 - - - - 0.00000008175 63.0
PYH2_k127_8490510_0 SMART CBS domain containing protein K07182 - - 3.867e-276 854.0
PYH2_k127_8490510_1 PFAM Exonuclease RNase T and DNA polymerase III K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000225 298.0
PYH2_k127_8490510_2 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000000000000000003183 191.0
PYH2_k127_8490510_3 Sodium:solute symporter family - - - 0.00000000000000000000000000000000000000000003114 163.0
PYH2_k127_8495458_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 9.976e-246 762.0
PYH2_k127_8495458_1 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 335.0
PYH2_k127_8495458_2 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000000000000000004491 219.0
PYH2_k127_8495458_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.0000000000000000000000000001487 114.0
PYH2_k127_8503155_0 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 527.0
PYH2_k127_8503155_1 - K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 306.0
PYH2_k127_8503155_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005717 239.0
PYH2_k127_8503155_4 Prokaryotic N-terminal methylation motif - - - 0.0000000000000000000000000000000000000000000000000000000001121 212.0
PYH2_k127_8503155_5 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000003662 195.0
PYH2_k127_8510137_0 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007127 310.0
PYH2_k127_8510137_1 Histidine kinase-like ATPase domain K01338,K04757,K06379,K08282,K17752 - 2.7.11.1,3.4.21.53 0.000000000000000000000000000000000000000000000000006298 184.0
PYH2_k127_8510137_2 - - - - 0.00000000000000000000003997 103.0
PYH2_k127_8510137_3 SPFH domain / Band 7 family - - - 0.0008835 45.0
PYH2_k127_8519349_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 8.924e-228 709.0
PYH2_k127_8519349_1 Belongs to the peptidase S16 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001509 546.0
PYH2_k127_8519349_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004563 472.0
PYH2_k127_8519349_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003708 460.0
PYH2_k127_8519349_4 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000000000000000000000000000000003622 239.0
PYH2_k127_8560154_0 Threonine synthase K01733 - 4.2.3.1 5.452e-297 917.0
PYH2_k127_8560154_1 Diguanylate cyclase - - - 4.999e-273 842.0
PYH2_k127_8560154_2 PFAM aminotransferase class I and II K14260 - 2.6.1.2,2.6.1.66 4.161e-267 823.0
PYH2_k127_8560154_3 homoserine dehydrogenase K00003 - 1.1.1.3 1.279e-263 814.0
PYH2_k127_8560154_4 auxin efflux carrier K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 472.0
PYH2_k127_8560154_5 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000000000000000000000000000000002281 222.0
PYH2_k127_8560154_6 periplasmic secreted protein - - - 0.00000000000000000000000004159 117.0
PYH2_k127_8560154_7 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000004132 98.0
PYH2_k127_8566689_0 Major facilitator Superfamily - - - 3.141e-236 735.0
PYH2_k127_8566689_1 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007322 299.0
PYH2_k127_8566689_2 - - - - 0.00000000000000000000000000000000000000000000000000000000002936 207.0
PYH2_k127_8566689_3 Rhodanese domain protein - - - 0.0000000000001245 70.0
PYH2_k127_8589846_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0 1262.0
PYH2_k127_8589846_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 1.281e-312 959.0
PYH2_k127_8589846_10 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006977 575.0
PYH2_k127_8589846_11 Belongs to the radical SAM superfamily. RlmN family K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004535 575.0
PYH2_k127_8589846_12 MJ0042 family finger-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 499.0
PYH2_k127_8589846_14 synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009378 452.0
PYH2_k127_8589846_15 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 349.0
PYH2_k127_8589846_16 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 331.0
PYH2_k127_8589846_17 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 306.0
PYH2_k127_8589846_18 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001381 278.0
PYH2_k127_8589846_19 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008978 264.0
PYH2_k127_8589846_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 2.718e-291 896.0
PYH2_k127_8589846_20 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009693 243.0
PYH2_k127_8589846_21 FxsA cytoplasmic membrane protein K07113 - - 0.000000000000000000000000000000000000000000000000000000000000000000007837 235.0
PYH2_k127_8589846_22 Thioredoxin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002774 231.0
PYH2_k127_8589846_23 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000007118 231.0
PYH2_k127_8589846_24 Divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000000000000000000000000000003395 214.0
PYH2_k127_8589846_26 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.00000000000000000000000000000000000002038 148.0
PYH2_k127_8589846_27 response regulator K08083 - - 0.000000000000000000000000000003272 119.0
PYH2_k127_8589846_3 acetyl-CoA carboxylase biotin carboxylase K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 3.121e-289 889.0
PYH2_k127_8589846_4 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 7.705e-222 691.0
PYH2_k127_8589846_5 HemY domain protein K02498 - - 3.078e-220 687.0
PYH2_k127_8589846_6 oxidoreductase FAD NAD(P)-binding domain protein K00523 - 1.17.1.1 2.063e-211 660.0
PYH2_k127_8589846_7 enzyme of heme biosynthesis K02496,K13543 - 2.1.1.107,4.2.1.75 3.94e-199 623.0
PYH2_k127_8589846_8 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 581.0
PYH2_k127_8589846_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 583.0
PYH2_k127_8622143_0 Sulfate transporter antisigma-factor antagonist STAS - - - 2.129e-232 721.0
PYH2_k127_8622143_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004484 614.0
PYH2_k127_8622143_2 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001791 275.0
PYH2_k127_8638220_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1262.0
PYH2_k127_8638220_1 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0 1067.0
PYH2_k127_8638220_10 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes K02405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000074 448.0
PYH2_k127_8638220_11 PFAM OmpA MotB domain protein K02557 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002685 428.0
PYH2_k127_8638220_12 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 302.0
PYH2_k127_8638220_13 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000674 295.0
PYH2_k127_8638220_14 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 290.0
PYH2_k127_8638220_15 Cyclase dehydrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009394 287.0
PYH2_k127_8638220_16 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 284.0
PYH2_k127_8638220_17 molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 281.0
PYH2_k127_8638220_18 PFAM FlgN family protein K02399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003219 281.0
PYH2_k127_8638220_19 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005466 280.0
PYH2_k127_8638220_2 PFAM transglutaminase domain protein K22452 - 2.3.2.13 2.905e-321 988.0
PYH2_k127_8638220_21 Ferredoxin 2Fe-2S type, ISC system K04755 - - 0.000000000000000000000000000000000000000000000000000000000000000005007 225.0
PYH2_k127_8638220_22 bacterial-type flagellum organization K02398 GO:0000988,GO:0000989,GO:0003674,GO:0008150,GO:0009889,GO:0009892,GO:0010556,GO:0010605,GO:0016989,GO:0019219,GO:0019222,GO:0030162,GO:0031323,GO:0031324,GO:0031326,GO:0032268,GO:0032269,GO:0045861,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0140110,GO:1903506,GO:2001141 - 0.0000000000000000000000000000000000000000000002957 169.0
PYH2_k127_8638220_23 Protein of unknown function (DUF2288) - - - 0.0000000000000000000000000000000000000000000007408 168.0
PYH2_k127_8638220_24 Belongs to the UPF0125 (RnfH) family K09801 - - 0.00000000000000000000000000000000000000001926 154.0
PYH2_k127_8638220_25 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.0000000000000000000000000000000000000001396 151.0
PYH2_k127_8638220_26 - K06078 - - 0.0000000000000000000000000000000000000001642 152.0
PYH2_k127_8638220_27 Fe-S assembly protein IscX - - - 0.000000000000000000000000000000143 124.0
PYH2_k127_8638220_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 9.408e-297 913.0
PYH2_k127_8638220_4 PFAM GTP-binding signal recognition particle SRP54 G- domain K02404 - - 1.2e-260 806.0
PYH2_k127_8638220_5 MoeA domain protein domain I and II K03750 - 2.10.1.1 1.332e-230 720.0
PYH2_k127_8638220_6 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 2.249e-211 660.0
PYH2_k127_8638220_7 Methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008664 531.0
PYH2_k127_8638220_8 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 474.0
PYH2_k127_8638220_9 PFAM MotA TolQ ExbB proton channel K02556 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001902 459.0
PYH2_k127_8655319_0 May be involved in recombinational repair of damaged DNA K03631 - - 1.293e-316 974.0
PYH2_k127_8655319_1 Belongs to the CarA family K01956 - 6.3.5.5 1.403e-232 721.0
PYH2_k127_8655319_10 Belongs to the CarB family K01955 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000003634 196.0
PYH2_k127_8655319_11 - - - - 0.0000000000000000000000000000000002818 141.0
PYH2_k127_8655319_2 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 4.694e-217 677.0
PYH2_k127_8655319_3 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 9.956e-211 656.0
PYH2_k127_8655319_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 565.0
PYH2_k127_8655319_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003662 487.0
PYH2_k127_8655319_6 Heme copper-type cytochrome quinol oxidase subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 368.0
PYH2_k127_8655319_7 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 289.0
PYH2_k127_8655319_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005276 273.0
PYH2_k127_8655319_9 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000005371 211.0
PYH2_k127_8660082_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 3.879e-294 941.0
PYH2_k127_8660082_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 382.0
PYH2_k127_8662360_0 glycosyl - - - 1.572e-207 648.0
PYH2_k127_8662360_1 permease - - - 5.566e-205 642.0
PYH2_k127_8662360_2 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 415.0
PYH2_k127_8662360_3 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 310.0
PYH2_k127_8662360_4 Protein of unknown function (DUF3301) - - - 0.00000000000000000000000000000000000000000000000000000000000002597 215.0
PYH2_k127_8662360_5 Cold shock protein K03704 - - 0.000000000000000000000000000000000000688 141.0
PYH2_k127_86890_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 6.598e-242 749.0
PYH2_k127_86890_1 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 2.64e-232 723.0
PYH2_k127_86890_10 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000000000001211 114.0
PYH2_k127_86890_11 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000003573 118.0
PYH2_k127_86890_2 mechanosensitive ion channel - - - 7.594e-219 684.0
PYH2_k127_86890_3 Mediates influx of magnesium ions K03284 - - 2.971e-214 667.0
PYH2_k127_86890_4 formate dehydrogenase, beta subunit - - - 3.504e-195 610.0
PYH2_k127_86890_5 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 430.0
PYH2_k127_86890_6 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 306.0
PYH2_k127_86890_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000001626 198.0
PYH2_k127_86890_8 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.000000000000000000000000000000000000000000000000001165 203.0
PYH2_k127_86890_9 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000000000000000000002411 162.0
PYH2_k127_8818832_0 Belongs to the methyltransferase superfamily K07444 - - 5.811e-223 693.0
PYH2_k127_8818832_1 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000000000005703 158.0
PYH2_k127_8818832_2 Stress responsive alpha-beta barrel - - - 0.000000000000000000000000000004205 119.0
PYH2_k127_883687_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001754 241.0
PYH2_k127_883687_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000000001684 185.0
PYH2_k127_883687_2 response regulator receiver K07814 - - 0.000000002715 58.0
PYH2_k127_8837563_0 PFAM NADH Ubiquinone plastoquinone (complex I) K05568 - - 3.641e-197 629.0
PYH2_k127_8837563_1 Proton-conducting membrane transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 394.0
PYH2_k127_8837563_2 PFAM NADH Ubiquinone plastoquinone - - - 0.00000057 53.0
PYH2_k127_8842392_0 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 544.0
PYH2_k127_8842392_1 The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters K02170 - 3.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 254.0
PYH2_k127_8842392_2 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000003357 224.0
PYH2_k127_8863968_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of hydrogenobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 589.0
PYH2_k127_8863968_1 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 GO:0003674,GO:0003824,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008939,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0017144,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042364,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.4.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 346.0
PYH2_k127_8863968_2 Nitroreductase family K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 334.0
PYH2_k127_8863968_3 Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000554 319.0
PYH2_k127_8863968_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003119 237.0
PYH2_k127_8863968_5 Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate K02231 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008819,GO:0008820,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016779,GO:0033554,GO:0044237,GO:0050896,GO:0051716,GO:0070568 2.7.1.156,2.7.7.62 0.00000000000000000000000000000000000000000000000000000000000000003553 226.0
PYH2_k127_8863968_6 COG4206 Outer membrane cobalamin receptor protein K16092 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015267,GO:0015318,GO:0015889,GO:0015893,GO:0016020,GO:0016021,GO:0019904,GO:0022803,GO:0022838,GO:0022857,GO:0031224,GO:0034220,GO:0042221,GO:0042493,GO:0044425,GO:0050896,GO:0051179,GO:0051180,GO:0051181,GO:0051234,GO:0055085,GO:0071702,GO:0071705 - 0.0000000000000000000000000000000000000002657 151.0
PYH2_k127_8871337_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 3.555e-292 896.0
PYH2_k127_8871337_1 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 604.0
PYH2_k127_8871337_2 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 417.0
PYH2_k127_8871337_3 - - - - 0.00000000000000000000000000000000000000000000000000000000297 202.0
PYH2_k127_8890392_0 O-methyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004152 269.0
PYH2_k127_8890392_1 HDOD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004371 277.0
PYH2_k127_890330_0 Ion channel K10716 - - 0.000000000000000000000000000006198 126.0
PYH2_k127_890330_1 Protein of unknown function (DUF1269) - - - 0.0000000000000000000002787 108.0
PYH2_k127_890330_2 response to heat K03668 - - 0.00007137 51.0
PYH2_k127_8919589_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 7.669e-264 821.0
PYH2_k127_8919589_1 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 4.191e-246 762.0
PYH2_k127_8919589_10 Belongs to the peptidase S24 family K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 378.0
PYH2_k127_8919589_11 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001931 346.0
PYH2_k127_8919589_13 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002316 271.0
PYH2_k127_8919589_14 Isochorismatase family K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000002808 255.0
PYH2_k127_8919589_15 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000002017 216.0
PYH2_k127_8919589_16 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000002053 192.0
PYH2_k127_8919589_2 PFAM UMUC domain protein DNA-repair protein K03502 - - 1.696e-245 760.0
PYH2_k127_8919589_3 Nicotinate phosphoribosyltransferase (NAPRTase) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 601.0
PYH2_k127_8919589_4 RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000736 572.0
PYH2_k127_8919589_5 ROK family K00845,K00847,K00884 - 2.7.1.2,2.7.1.4,2.7.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007403 568.0
PYH2_k127_8919589_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 520.0
PYH2_k127_8919589_7 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 416.0
PYH2_k127_8919589_8 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 411.0
PYH2_k127_8919589_9 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 422.0
PYH2_k127_896145_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 3.195e-268 826.0
PYH2_k127_896145_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005517 333.0
PYH2_k127_896145_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 302.0
PYH2_k127_8972950_0 GAF domain K20962 - 3.1.4.52 0.0 1407.0
PYH2_k127_8972950_1 Belongs to the peptidase S16 family - - - 0.0 1143.0
PYH2_k127_8972950_2 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001704 273.0
PYH2_k127_8972950_3 signal transduction protein - - - 0.000000000000000000000000000000000000004436 149.0
PYH2_k127_897729_0 RNA polymerase sigma factor RpoS K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 509.0
PYH2_k127_897729_1 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 482.0
PYH2_k127_897729_2 peptidase K06194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 466.0
PYH2_k127_897729_3 Sigma factor PP2C-like phosphatases K20977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 473.0
PYH2_k127_897729_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 419.0
PYH2_k127_897729_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006512 383.0
PYH2_k127_897729_6 STAS domain K20978 - - 0.000000000000000000000000003103 113.0
PYH2_k127_8987254_0 ATPase. Has a role at an early stage in the morphogenesis of the spore coat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 507.0
PYH2_k127_8987254_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 357.0
PYH2_k127_8987254_2 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002913 340.0
PYH2_k127_8987254_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005309 306.0
PYH2_k127_8987254_4 glyoxalase K07032 - - 0.0000000000000000000000000000000000000000000000000000000000000000006909 230.0
PYH2_k127_8987254_5 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000000000000000000000000000001359 172.0
PYH2_k127_8990714_0 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1325.0
PYH2_k127_8990714_1 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006069 478.0
PYH2_k127_8990714_2 protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 347.0
PYH2_k127_8990714_3 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 323.0
PYH2_k127_8990714_4 protein conserved in bacteria K09796 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002901 284.0
PYH2_k127_8990714_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006801 274.0
PYH2_k127_8990714_6 PFAM Carbohydrate-selective porin OprB K07267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 278.0
PYH2_k127_8990714_7 Protein of unknown function (DUF3135) - - - 0.0000000000000000000005813 99.0
PYH2_k127_8990714_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000001896 66.0
PYH2_k127_9081624_0 PFAM glycosyl transferase family 39 - - - 0.0 1023.0
PYH2_k127_9081624_1 Acid phosphatase homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 475.0
PYH2_k127_9081624_2 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 381.0
PYH2_k127_9081624_3 Small Multidrug Resistance protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
PYH2_k127_9081624_4 PFAM glycosyl transferase family 39 - - - 0.000000000000000000000000000000000000000000000000000000000000000001056 228.0
PYH2_k127_9104733_0 peptidase - - - 2.12e-262 812.0
PYH2_k127_9104733_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 4.562e-248 767.0
PYH2_k127_9149195_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 2.767e-225 700.0
PYH2_k127_9149195_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 1.927e-199 624.0
PYH2_k127_9149195_2 Aminotransferase class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 526.0
PYH2_k127_9149195_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 406.0
PYH2_k127_9149195_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 391.0
PYH2_k127_9149195_5 Predicted membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001059 363.0
PYH2_k127_9149195_6 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002552 315.0
PYH2_k127_9149195_7 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000000000000000000000007067 163.0
PYH2_k127_9149195_9 Stress responsive alpha-beta barrel - - - 0.0000000000000007261 76.0
PYH2_k127_9163051_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0 1226.0
PYH2_k127_9163051_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003769 282.0
PYH2_k127_9163051_2 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001998 281.0
PYH2_k127_9163051_3 endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000004908 245.0
PYH2_k127_9163051_4 Flagellar protein YcgR - - - 0.0000000000000000000000000006664 129.0
PYH2_k127_9163051_5 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000003363 104.0
PYH2_k127_9163051_6 sequence-specific DNA binding - - - 0.0006452 48.0
PYH2_k127_922297_0 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 459.0
PYH2_k127_922297_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009381 361.0
PYH2_k127_922297_10 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000000000000000001068 182.0
PYH2_k127_922297_11 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000002155 169.0
PYH2_k127_922297_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000000000007726 169.0
PYH2_k127_922297_13 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000005297 115.0
PYH2_k127_922297_14 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.00000000000000000000513 92.0
PYH2_k127_922297_2 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 337.0
PYH2_k127_922297_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009314 252.0
PYH2_k127_922297_4 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001402 244.0
PYH2_k127_922297_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000003081 231.0
PYH2_k127_922297_6 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000000000000000000000000001713 225.0
PYH2_k127_922297_7 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000000000000009142 216.0
PYH2_k127_922297_8 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000000000000003412 210.0
PYH2_k127_922297_9 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.00000000000000000000000000000000000000000000000000001665 188.0
PYH2_k127_925260_0 exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 523.0
PYH2_k127_925260_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 414.0
PYH2_k127_925260_2 AmpG muropeptide MFS transporter K08218 K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009153 284.0
PYH2_k127_935647_0 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 416.0
PYH2_k127_935647_1 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 361.0
PYH2_k127_935647_2 Haem-degrading - - - 0.000000000000000000000000000000000000000000000004158 175.0
PYH2_k127_935647_3 Trm112p-like protein K09791 - - 0.0000000000000000000007635 94.0
PYH2_k127_975926_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1495.0
PYH2_k127_975926_1 Histidine kinase - - - 0.0 1246.0
PYH2_k127_975926_10 DNA protecting protein DprA K04096 - - 6.579e-206 643.0
PYH2_k127_975926_11 - - - - 7.251e-198 619.0
PYH2_k127_975926_12 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008487 530.0
PYH2_k127_975926_13 NYN domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 528.0
PYH2_k127_975926_14 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 521.0
PYH2_k127_975926_15 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003681 455.0
PYH2_k127_975926_16 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 435.0
PYH2_k127_975926_17 Predicted integral membrane protein (DUF2189) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 433.0
PYH2_k127_975926_18 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005728 368.0
PYH2_k127_975926_19 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008238 312.0
PYH2_k127_975926_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1202.0
PYH2_k127_975926_20 Belongs to the Smg family K03747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 299.0
PYH2_k127_975926_21 Protein of unknown function (DUF4197) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002318 262.0
PYH2_k127_975926_22 PFAM cytochrome c, class I K08738 - - 0.000000000000000000000000000000008676 129.0
PYH2_k127_975926_23 VanZ like family - - - 0.00000000000000000000031 106.0
PYH2_k127_975926_24 Selenoprotein, putative - - - 0.000000000000000002196 86.0
PYH2_k127_975926_25 Protein of unknown function, DUF255 K06888 - - 0.000000000000001858 79.0
PYH2_k127_975926_26 Protein of unknown function, DUF255 K06888 - - 0.000000002561 58.0
PYH2_k127_975926_27 Protein of unknown function, DUF255 K06888 - - 0.00000000565 57.0
PYH2_k127_975926_28 PFAM Hemerythrin HHE cation binding domain K07216 - - 0.000000008318 59.0
PYH2_k127_975926_3 Transport of potassium into the cell K03549 - - 0.0 1193.0
PYH2_k127_975926_4 type II secretion system protein E K02454,K02652,K12276 - - 0.0 1140.0
PYH2_k127_975926_5 PFAM Carbon starvation protein CstA K06200 - - 0.0 1138.0
PYH2_k127_975926_6 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 5.649e-254 785.0
PYH2_k127_975926_7 response regulator - - - 7.832e-244 756.0
PYH2_k127_975926_8 Amino acid permease K03294 - - 5.638e-226 707.0
PYH2_k127_975926_9 PFAM Peptidoglycan-binding LysM - - - 4.901e-212 660.0