Overview

ID MAG03212
Name PYH3_bin.10
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Thermoanaerobaculia
Order UBA5066
Family UBA5066
Genus DAOMFB01
Species
Assembly information
Completeness (%) 77.2
Contamination (%) 1.16
GC content (%) 69.0
N50 (bp) 9,072
Genome size (bp) 3,069,929

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2671

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1049016_0 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006889 332.0
PYH3_k127_1049016_1 Transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 288.0
PYH3_k127_1049016_2 SMART Elongator protein 3 MiaB NifB K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000006822 252.0
PYH3_k127_1049016_3 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000001317 134.0
PYH3_k127_1049016_4 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009314,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0031668,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000003019 115.0
PYH3_k127_1054726_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 404.0
PYH3_k127_1054726_1 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00756,K00758 - 2.4.2.2,2.4.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006885 393.0
PYH3_k127_1054726_2 Multidrug ABC transporter ATP-binding protein K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 377.0
PYH3_k127_1054726_3 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.0000000000000000000000000000001048 127.0
PYH3_k127_1081388_0 Acyl-CoA dehydrogenase, N-terminal domain - - - 9.032e-204 641.0
PYH3_k127_1081388_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 609.0
PYH3_k127_1081388_2 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 496.0
PYH3_k127_1081388_3 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 407.0
PYH3_k127_1081388_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 390.0
PYH3_k127_1081388_5 COG1073 Hydrolases of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000002101 157.0
PYH3_k127_1081388_6 nuclease activity - - - 0.00000000000000000000000000000005125 129.0
PYH3_k127_1081388_7 Bacterial antitoxin of type II TA system, VapB - - - 0.00000000000006155 73.0
PYH3_k127_1081388_8 Type VI secretion system (T6SS), amidase effector protein 4 - - - 0.0000001154 60.0
PYH3_k127_109772_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 389.0
PYH3_k127_109772_1 PASTA K08884,K12132 GO:0000270,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0006022,GO:0006023,GO:0006024,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008047,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009252,GO:0009273,GO:0009605,GO:0009607,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0010698,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0022603,GO:0022604,GO:0030145,GO:0030203,GO:0030234,GO:0030312,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032091,GO:0034645,GO:0036211,GO:0040007,GO:0042304,GO:0042546,GO:0042802,GO:0043085,GO:0043086,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043388,GO:0043393,GO:0043412,GO:0044036,GO:0044038,GO:0044085,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044419,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046872,GO:0046890,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050790,GO:0050793,GO:0050794,GO:0050896,GO:0051055,GO:0051098,GO:0051099,GO:0051100,GO:0051101,GO:0051128,GO:0051701,GO:0051704,GO:0051707,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0062012,GO:0062014,GO:0065007,GO:0065008,GO:0065009,GO:0070589,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:0075136,GO:0080090,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000009171 237.0
PYH3_k127_109772_2 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000005349 190.0
PYH3_k127_1120206_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.908e-248 782.0
PYH3_k127_1120206_1 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.0000000000000000000000000000000000000000000000000000005 216.0
PYH3_k127_1120206_2 Belongs to the ompA family - - - 0.00000000000000000000000000000000000000000000000009313 198.0
PYH3_k127_1120206_3 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000193 104.0
PYH3_k127_1158876_0 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 343.0
PYH3_k127_1158876_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 339.0
PYH3_k127_1158876_10 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0000166,GO:0000287,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016020,GO:0016114,GO:0016740,GO:0016772,GO:0016779,GO:0019103,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0032549,GO:0032551,GO:0032553,GO:0032557,GO:0032787,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044464,GO:0046490,GO:0046872,GO:0046914,GO:0050518,GO:0051483,GO:0051484,GO:0070567,GO:0071704,GO:0071944,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901576 2.7.7.60 0.000000274 55.0
PYH3_k127_1158876_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001153 297.0
PYH3_k127_1158876_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007261 284.0
PYH3_k127_1158876_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005085,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0019899,GO:0034641,GO:0034645,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0051020,GO:0065007,GO:0065009,GO:0071704,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000002566 226.0
PYH3_k127_1158876_5 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000002496 184.0
PYH3_k127_1158876_6 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000003348 177.0
PYH3_k127_1158876_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000007055 160.0
PYH3_k127_1158876_8 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.000000000000000000000000000000000002023 145.0
PYH3_k127_1158876_9 Belongs to the HAM1 NTPase family K02428 - 3.6.1.66 0.00000000000000000000000000000008376 145.0
PYH3_k127_1204501_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 5.691e-216 702.0
PYH3_k127_1204501_1 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 499.0
PYH3_k127_1204501_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 445.0
PYH3_k127_1204501_3 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005712 273.0
PYH3_k127_1204501_4 Proteasome subunit K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000001293 223.0
PYH3_k127_1204501_5 TIGRFAM DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000001064 181.0
PYH3_k127_1204501_6 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.00000000000000000000000000000000000000000000007774 181.0
PYH3_k127_1204501_7 Cytochrome c - - - 0.000000001797 66.0
PYH3_k127_1216861_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 454.0
PYH3_k127_1216861_1 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000001716 132.0
PYH3_k127_1216861_2 CutA1 divalent ion tolerance protein K03926 - - 0.0000000000000000000004226 100.0
PYH3_k127_1236546_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002604 496.0
PYH3_k127_1236546_1 histidine kinase, HAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000005341 259.0
PYH3_k127_1236546_2 Redoxin - - - 0.00000000000000000006178 102.0
PYH3_k127_1236546_3 homoserine transmembrane transporter activity - - - 0.000000007903 65.0
PYH3_k127_1248520_0 Dehydrogenase K00248,K09478 - 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 450.0
PYH3_k127_1248520_1 protein-disulfide reductase activity K04084,K06196 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003912 401.0
PYH3_k127_1248520_2 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 381.0
PYH3_k127_1248520_3 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000179 198.0
PYH3_k127_1248520_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000001201 141.0
PYH3_k127_1248520_5 Lipopolysaccharide kinase (Kdo/WaaP) family K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000001506 149.0
PYH3_k127_1248520_6 Psort location OuterMembrane, score - - - 0.0000000000000000000000000000000001959 142.0
PYH3_k127_1248520_7 Domain of unknown function (DUF4136) - - - 0.000000000000000000000007154 110.0
PYH3_k127_1248520_8 2Fe-2S -binding domain - - - 0.0000000005909 65.0
PYH3_k127_1248520_9 Thioredoxin-like - - - 0.0003094 52.0
PYH3_k127_1280620_0 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000021 274.0
PYH3_k127_1280620_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000004343 286.0
PYH3_k127_1280620_2 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000000000001015 153.0
PYH3_k127_1280620_3 Autotransporter beta-domain - - - 0.0000001936 66.0
PYH3_k127_1300149_0 ATP-dependent helicase activity K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 371.0
PYH3_k127_1300149_1 protein phosphatase 2C domain protein K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000001443 227.0
PYH3_k127_1300149_2 - - - - 0.0000000000000000000000000000005282 135.0
PYH3_k127_1300149_3 Helix-turn-helix domain - - - 0.0000000002266 64.0
PYH3_k127_1300149_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000385 69.0
PYH3_k127_1315117_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679,K01744 - 4.2.1.2,4.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004364 590.0
PYH3_k127_1315117_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 345.0
PYH3_k127_1315212_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 570.0
PYH3_k127_1315212_1 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 479.0
PYH3_k127_131961_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000002346 170.0
PYH3_k127_131961_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000002412 147.0
PYH3_k127_131961_2 Protein of unknown function (DUF971) K03593 - - 0.00000000000000000000000004663 113.0
PYH3_k127_131961_3 B12 binding domain - - - 0.000000000000000000001497 104.0
PYH3_k127_131961_4 MacB-like periplasmic core domain K02004 - - 0.0000000001515 61.0
PYH3_k127_1324122_0 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002987 264.0
PYH3_k127_1324122_1 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000001033 168.0
PYH3_k127_1324122_2 Fibronectin, type III domain - - - 0.000000000000000000001516 108.0
PYH3_k127_1336919_0 Amino acid permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 617.0
PYH3_k127_1336919_1 helicase superfamily c-terminal domain K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 441.0
PYH3_k127_1337033_0 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000003625 222.0
PYH3_k127_1337033_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000002292 105.0
PYH3_k127_1337033_2 Regulatory protein, FmdB - - - 0.000000000000000001305 90.0
PYH3_k127_1351628_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.99e-246 803.0
PYH3_k127_1351628_1 enoyl-CoA hydratase K13766 - 4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000084 260.0
PYH3_k127_1351628_10 outer membrane autotransporter barrel domain protein - - - 0.00000003683 66.0
PYH3_k127_1351628_2 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002734 249.0
PYH3_k127_1351628_3 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000009071 192.0
PYH3_k127_1351628_4 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000001238 162.0
PYH3_k127_1351628_5 DinB family - - - 0.00000000000000000000000000000000000001254 154.0
PYH3_k127_1351628_6 cheY-homologous receiver domain - - - 0.00000000000000000000000000000009886 138.0
PYH3_k127_1351628_7 bacterial (prokaryotic) histone like domain K03530 - - 0.00000000000000000000000004275 110.0
PYH3_k127_1351628_8 Competence protein ComEC K02238 - - 0.000000000000000000000007223 116.0
PYH3_k127_1351628_9 PFAM Type II secretion system protein E K02454,K02652 - - 0.00000000000002602 87.0
PYH3_k127_1358780_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 373.0
PYH3_k127_1358780_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004727 279.0
PYH3_k127_1358780_2 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000006339 190.0
PYH3_k127_1358780_3 structural constituent of ribosome K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000769 162.0
PYH3_k127_1358780_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0001521 55.0
PYH3_k127_1367899_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 293.0
PYH3_k127_1367899_1 PFAM Peptidase M16 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004912 287.0
PYH3_k127_1367899_2 PFAM Peptidase M16 - - - 0.000000000000000000000000000000000003921 159.0
PYH3_k127_139143_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1220.0
PYH3_k127_139143_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007705 593.0
PYH3_k127_139143_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005329 465.0
PYH3_k127_139143_3 Domain of unknown function (DUF4178) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 430.0
PYH3_k127_139143_4 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.00000000000000000004118 99.0
PYH3_k127_139143_5 Protein of unknown function (DUF2950) - - - 0.0000000000000005609 77.0
PYH3_k127_1395279_0 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 5.763e-247 776.0
PYH3_k127_1395279_1 Redoxin K03564 - 1.11.1.15 0.000000000000000000002415 96.0
PYH3_k127_1395279_2 PFAM AhpC TSA family K03564 - 1.11.1.15 0.0000000000002909 70.0
PYH3_k127_1395279_3 Bacteriophage replication gene A protein (GPA) - - - 0.00000000002951 63.0
PYH3_k127_1395279_4 cell cycle K05589,K12065,K13052 - - 0.0000008334 55.0
PYH3_k127_1407403_0 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 353.0
PYH3_k127_1407403_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000434 278.0
PYH3_k127_1407403_2 PFAM Allophanate hydrolase subunit 2 - - - 0.00000000000000000000000000000000000000000000000000000000000881 224.0
PYH3_k127_1407403_3 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000004069 196.0
PYH3_k127_1407403_4 LamB/YcsF family K07160 - - 0.000000000000000000000000000000000000001046 163.0
PYH3_k127_1407403_5 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000002214 145.0
PYH3_k127_1407403_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000003218 87.0
PYH3_k127_1407403_7 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000000003115 64.0
PYH3_k127_1422523_0 Converts 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1- carboxylate (SHCHC) to 2-succinylbenzoate (OSB) K02549 - 4.2.1.113 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 301.0
PYH3_k127_1422523_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000005014 248.0
PYH3_k127_1422523_2 SCO1/SenC K07152 - - 0.00000000000000000000000000000000003043 145.0
PYH3_k127_1422523_3 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000004164 139.0
PYH3_k127_1422523_4 Hpt domain - - - 0.0000000000000000000000005393 119.0
PYH3_k127_1422523_5 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000000000754 101.0
PYH3_k127_1423535_0 Ribonuclease E/G family K08300,K08301 GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005856,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008996,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360 3.1.26.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 497.0
PYH3_k127_1423535_1 Belongs to the SEDS family K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000001603 238.0
PYH3_k127_1469262_0 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007485 580.0
PYH3_k127_1469262_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 558.0
PYH3_k127_1469262_10 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000002637 54.0
PYH3_k127_1469262_11 oxidoreductase activity - - - 0.00001605 57.0
PYH3_k127_1469262_2 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 528.0
PYH3_k127_1469262_3 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 452.0
PYH3_k127_1469262_4 Domain of unknown function (DUF4143) K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 380.0
PYH3_k127_1469262_5 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001394 291.0
PYH3_k127_1469262_6 SMART serine threonine protein kinase - - - 0.000000000000000000000001397 119.0
PYH3_k127_1469262_7 Encoded by - - - 0.00000000000002998 84.0
PYH3_k127_1469262_8 Amidohydrolase family - - - 0.0000000001107 74.0
PYH3_k127_1469262_9 Peptidase M56 - - - 0.0000000002217 73.0
PYH3_k127_1471626_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 512.0
PYH3_k127_1471626_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 359.0
PYH3_k127_1471626_2 Cytochrome c554 and c-prime K03620 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003375 283.0
PYH3_k127_1471626_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.000000000000000000000000000000000000000004125 166.0
PYH3_k127_1485980_0 Prolyl oligopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 552.0
PYH3_k127_1485980_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007285 479.0
PYH3_k127_1485980_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002959 373.0
PYH3_k127_1485980_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 327.0
PYH3_k127_1485980_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 326.0
PYH3_k127_1485980_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000001435 187.0
PYH3_k127_1485980_6 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000412 166.0
PYH3_k127_1485980_7 lipoprotein localization to outer membrane K02004,K09808 - - 0.00000000000000000000000000003392 121.0
PYH3_k127_1485980_8 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000002649 88.0
PYH3_k127_1485980_9 - - - - 0.000003077 57.0
PYH3_k127_1502983_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 6.939e-200 640.0
PYH3_k127_1502983_1 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009323 534.0
PYH3_k127_1502983_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 456.0
PYH3_k127_1502983_3 COG1680 Beta-lactamase class C and other penicillin binding proteins K01286 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 387.0
PYH3_k127_1502983_4 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004163 355.0
PYH3_k127_1502983_5 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006346 256.0
PYH3_k127_1502983_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000003929 215.0
PYH3_k127_1502983_7 Carboxymuconolactone decarboxylase family - - - 0.000001185 54.0
PYH3_k127_1502983_8 Efflux ABC transporter, permease protein K02004 - - 0.0002728 52.0
PYH3_k127_1502983_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K21137 - - 0.0002999 44.0
PYH3_k127_1508193_0 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
PYH3_k127_1508193_1 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744,K09774,K22110 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0006810,GO:0008150,GO:0008643,GO:0008645,GO:0009279,GO:0015267,GO:0015288,GO:0015749,GO:0015750,GO:0015751,GO:0015757,GO:0016020,GO:0019867,GO:0022803,GO:0022829,GO:0022857,GO:0030312,GO:0030313,GO:0031975,GO:0034219,GO:0044462,GO:0044464,GO:0046323,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:1904659 - 0.000000000000000000000000000000000000000000001365 190.0
PYH3_k127_1508193_2 PFAM phosphatidate cytidylyltransferase - - - 0.00002784 58.0
PYH3_k127_1547643_0 TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001463 294.0
PYH3_k127_1547643_1 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000002221 113.0
PYH3_k127_1596226_0 transporter, DctM subunit K11690 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 623.0
PYH3_k127_1596226_1 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 346.0
PYH3_k127_1596226_2 TRAP transporter T-component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 326.0
PYH3_k127_1596226_3 protein homotetramerization - GO:0003674,GO:0005215,GO:0005216,GO:0005261,GO:0005267,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015267,GO:0015318,GO:0015672,GO:0016043,GO:0022607,GO:0022803,GO:0022838,GO:0022840,GO:0022841,GO:0022842,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0043933,GO:0044085,GO:0046873,GO:0051179,GO:0051234,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055085,GO:0065003,GO:0071804,GO:0071805,GO:0071840,GO:0098655,GO:0098660,GO:0098662 - 0.0000000000000000000000000000000000000000000000000694 187.0
PYH3_k127_1596226_5 Belongs to the pirin family K06911 - - 0.000004554 52.0
PYH3_k127_1655788_0 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.563e-201 638.0
PYH3_k127_1655788_1 B12 binding domain - - - 9.321e-201 644.0
PYH3_k127_1655788_2 associated with various cellular activities K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 488.0
PYH3_k127_1655788_3 MgtE intracellular N domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001846 304.0
PYH3_k127_1655788_4 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003523 259.0
PYH3_k127_1655788_5 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000117 153.0
PYH3_k127_1655788_6 SMART Tetratricopeptide - - - 0.00000000000009646 85.0
PYH3_k127_1655788_8 - - - - 0.000008272 57.0
PYH3_k127_1655788_9 VanZ like family - - - 0.0009063 52.0
PYH3_k127_1677112_0 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 561.0
PYH3_k127_1677112_1 Protein of avirulence locus involved in temperature-dependent protein secretion K03217,K11898 - - 0.000000000000000000000000000000000000000000000000000000000000000000004462 244.0
PYH3_k127_1677112_2 TIGRFAM type VI secretion-associated protein, ImpA family K11902 - - 0.000000000000000000000000000000000000000000000000000000000000000001755 241.0
PYH3_k127_1677112_3 Type VI secretion system, VipA, VC_A0107 or Hcp2 K11901 - - 0.0000000000000000000000000000000000000000000000000000000001102 208.0
PYH3_k127_1677112_4 Type VI secretion system effector, Hcp K11903 - - 0.0000000000000000000000000000000000000000000000000002235 191.0
PYH3_k127_1677112_5 type VI secretion system effector K11903 - - 0.0000000000000000000009599 100.0
PYH3_k127_1697237_0 Site-specific recombinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 421.0
PYH3_k127_1697237_1 Mechanosensitive ion channel K16052 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 330.0
PYH3_k127_1697237_2 (twin-arginine translocation) pathway signal - - - 0.00000000000000000000000000003541 125.0
PYH3_k127_1697237_3 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) K03455 - - 0.000000000000000000000000002055 119.0
PYH3_k127_1711492_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008676 235.0
PYH3_k127_1711492_1 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000001686 200.0
PYH3_k127_1721932_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1365.0
PYH3_k127_1721932_1 - - - - 0.0 1022.0
PYH3_k127_1721932_10 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 344.0
PYH3_k127_1721932_11 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009762 322.0
PYH3_k127_1721932_12 PFAM secretion protein HlyD family protein K03543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002224 312.0
PYH3_k127_1721932_13 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005641 267.0
PYH3_k127_1721932_16 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000003359 126.0
PYH3_k127_1721932_17 Nucleotidyltransferase domain K07075 - - 0.00000000000000000000001805 104.0
PYH3_k127_1721932_18 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.0000000000000000000000277 114.0
PYH3_k127_1721932_19 - - - - 0.00000000000000000001208 96.0
PYH3_k127_1721932_2 acyl-CoA dehydrogenase - - - 9.871e-235 741.0
PYH3_k127_1721932_20 Protein tyrosine kinase - - - 0.00000000000003759 74.0
PYH3_k127_1721932_21 - - - - 0.0000000000001513 84.0
PYH3_k127_1721932_22 aminopeptidase N - - - 0.0000000000005419 81.0
PYH3_k127_1721932_23 Adenylate cyclase - - - 0.000000005089 63.0
PYH3_k127_1721932_24 Transglutaminase-like superfamily - - - 0.000002219 50.0
PYH3_k127_1721932_25 Protein of unknown function DUF86 - - - 0.0005734 46.0
PYH3_k127_1721932_3 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 5.161e-194 617.0
PYH3_k127_1721932_4 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 601.0
PYH3_k127_1721932_5 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 596.0
PYH3_k127_1721932_6 Acetylornithine deacetylase Succinyl-diaminopimelate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 591.0
PYH3_k127_1721932_7 signal peptide peptidase K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 517.0
PYH3_k127_1721932_8 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 370.0
PYH3_k127_1721932_9 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 350.0
PYH3_k127_1723901_0 TIGRFAM succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 1.26e-197 619.0
PYH3_k127_1723901_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 400.0
PYH3_k127_1723901_2 - K00241 - - 0.00000000000000000000000000000000000000000000000000000000000001843 223.0
PYH3_k127_1728386_0 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000001316 192.0
PYH3_k127_1728386_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000001539 132.0
PYH3_k127_1728386_2 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000286 131.0
PYH3_k127_1728386_3 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.0000000000000000000000003607 112.0
PYH3_k127_1728386_4 protein histidine kinase activity - - - 0.000000000000000000004906 107.0
PYH3_k127_1728386_5 cellulase activity - - - 0.00004023 50.0
PYH3_k127_1741464_0 Biogenesis protein - - - 0.00000000000000000000000000000000001415 144.0
PYH3_k127_1741464_1 diguanylate cyclase - - - 0.00000000000000000000000000000000006703 138.0
PYH3_k127_1741464_2 ArgK protein K07588 - - 0.000000000000000000000001617 116.0
PYH3_k127_1741464_3 ArgK protein K07588 - - 0.0000000000000005499 79.0
PYH3_k127_1765814_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1298.0
PYH3_k127_1765814_1 Belongs to the carbamoyltransferase HypF family K04656 - - 1.349e-260 828.0
PYH3_k127_1765814_2 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 537.0
PYH3_k127_1765814_3 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 436.0
PYH3_k127_1765814_4 Biotin-lipoyl like K07799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003485 336.0
PYH3_k127_1765814_5 CyaE is necessary for transport of calmodulin-sensitive adenylate cyclase-hemolysin (cyclolysin) K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002026 289.0
PYH3_k127_1765814_6 Protein of unknown function (DUF2911) - - - 0.00000000000000000000000000000000000000000000001447 190.0
PYH3_k127_1765814_7 - - - - 0.000000000000000000000005581 109.0
PYH3_k127_1765814_8 HupF/HypC family K04653 - - 0.000000000000000000012 96.0
PYH3_k127_1765814_9 homoserine transmembrane transporter activity K06600,K06895 - - 0.0000008636 54.0
PYH3_k127_1777985_0 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.0 1147.0
PYH3_k127_1777985_1 Hydrolase CocE NonD family - - - 4.165e-321 1000.0
PYH3_k127_1777985_2 SMART Elongator protein 3 MiaB NifB - - - 2.554e-209 664.0
PYH3_k127_1777985_3 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 534.0
PYH3_k127_1777985_4 Receptor - - - 0.000000000000000000000000002373 129.0
PYH3_k127_178679_0 ABC transporter, transmembrane K18890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003697 551.0
PYH3_k127_178679_1 ABC transporter, transmembrane K18889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 500.0
PYH3_k127_178679_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 467.0
PYH3_k127_178679_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 413.0
PYH3_k127_178679_4 Bacterial protein of unknown function (DUF885) - - - 0.0000000000000000000000000000000000000000000000000000000000000001113 246.0
PYH3_k127_178679_5 Domain of unknown function (DUF4412) - - - 0.0000000000000000000000000000000000000264 155.0
PYH3_k127_178679_6 Domain of unknown function (DUF4301) - - - 0.000000000000000000000000000000004032 143.0
PYH3_k127_178679_7 Domain of unknown function (DUF4412) - - - 0.00000000000000000000000000000001165 139.0
PYH3_k127_178679_8 P-type ATPase K17686 - 3.6.3.54 0.000000000000000807 79.0
PYH3_k127_1800239_0 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.000000000002705 79.0
PYH3_k127_1842252_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005845 541.0
PYH3_k127_1842252_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 526.0
PYH3_k127_1842252_2 6-O-methylguanine DNA methyltransferase, DNA binding domain K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 373.0
PYH3_k127_1842252_3 belongs to the thioredoxin family K20444,K20543 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003738 274.0
PYH3_k127_1842252_4 belongs to the thioredoxin family K20444,K20543 - - 0.000000000000000000005336 106.0
PYH3_k127_1842252_5 PFAM glycosyl transferase family 39 - - - 0.000000000000000054 91.0
PYH3_k127_1842252_6 positive regulation of growth - - - 0.0000000001202 65.0
PYH3_k127_1842252_7 PIN domain - - - 0.00001757 54.0
PYH3_k127_1842252_8 repeat-containing protein - - - 0.0001078 52.0
PYH3_k127_1926234_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003078 347.0
PYH3_k127_1926234_1 PFAM Transposase IS200 like - - - 0.000000000000000000000000000000000000000005076 156.0
PYH3_k127_192888_0 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006517 310.0
PYH3_k127_192888_1 Glycosyl transferase 4-like domain - - - 0.00000000000000000000000000000000000000000000007369 180.0
PYH3_k127_192888_2 Glycosyltransferase, group 1 family protein - - - 0.00000000000000000000000000000000000000000119 178.0
PYH3_k127_1932881_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 568.0
PYH3_k127_1932881_1 PFAM Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003732 531.0
PYH3_k127_1932881_10 PFAM Sodium sulfate symporter transmembrane region K14445 - - 0.0000000000000326 74.0
PYH3_k127_1932881_11 Protein of unknown function (DUF1697) - - - 0.000229 51.0
PYH3_k127_1932881_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 411.0
PYH3_k127_1932881_3 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000913 279.0
PYH3_k127_1932881_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000003943 191.0
PYH3_k127_1932881_5 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000000000000000000000000000000000000000005448 171.0
PYH3_k127_1932881_6 - - - - 0.0000000000000000000000000000000000000005371 156.0
PYH3_k127_1932881_7 Uncharacterized protein conserved in bacteria (DUF2314) - - - 0.0000000000000000000000000001141 121.0
PYH3_k127_1932881_8 PFAM CBS domain - - - 0.000000000000000000000000003248 123.0
PYH3_k127_1932881_9 TfoX N-terminal domain - - - 0.00000000000000000000000008983 113.0
PYH3_k127_1942830_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 338.0
PYH3_k127_1942830_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001426 285.0
PYH3_k127_1942830_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.00000000000000000000000000000000000000000000000000000000000000002201 233.0
PYH3_k127_1942830_3 bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000002836 93.0
PYH3_k127_1942830_4 outer membrane lipoprotein carrier protein LolA K03634 - - 0.0000000000008515 78.0
PYH3_k127_1946532_0 Sortilin, neurotensin receptor 3, - - - 0.0 1225.0
PYH3_k127_1946532_1 cellulose binding - - - 7.12e-263 844.0
PYH3_k127_1946532_10 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 342.0
PYH3_k127_1946532_11 saccharopine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005608 294.0
PYH3_k127_1946532_12 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000006352 243.0
PYH3_k127_1946532_13 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000006656 222.0
PYH3_k127_1946532_14 DinB family - - - 0.00000000000000000000000000000005089 142.0
PYH3_k127_1946532_15 RNA recognition motif - - - 0.0000000000000000000002115 103.0
PYH3_k127_1946532_16 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000008206 101.0
PYH3_k127_1946532_17 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000001755 93.0
PYH3_k127_1946532_2 ABC transporter transmembrane K11085 - - 5.796e-252 808.0
PYH3_k127_1946532_3 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009601 511.0
PYH3_k127_1946532_4 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005085 499.0
PYH3_k127_1946532_5 COGs COG1022 Long-chain acyl-CoA synthetase (AMP-forming) K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 487.0
PYH3_k127_1946532_6 Protein of unknown function (DUF1015) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 431.0
PYH3_k127_1946532_7 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 427.0
PYH3_k127_1946532_8 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003096 373.0
PYH3_k127_1946532_9 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 353.0
PYH3_k127_1985652_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000001996 215.0
PYH3_k127_1985652_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000005874 187.0
PYH3_k127_1985652_2 denitrification pathway - - - 0.0000000000000000000000000000000000000000000000017 197.0
PYH3_k127_1985652_3 amine dehydrogenase activity - - - 0.0000000000000000000000000000000001926 151.0
PYH3_k127_1985652_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000002054 65.0
PYH3_k127_1985652_5 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000003572 59.0
PYH3_k127_1985652_6 Kelch motif - - - 0.0003146 50.0
PYH3_k127_1993701_0 LmbE family - - - 1.098e-230 740.0
PYH3_k127_1993701_1 Amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 452.0
PYH3_k127_1993701_2 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005017 421.0
PYH3_k127_1993701_3 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 383.0
PYH3_k127_1993701_4 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 386.0
PYH3_k127_1993701_5 cAMP biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001882 273.0
PYH3_k127_1993701_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000002475 232.0
PYH3_k127_1993701_7 PFAM CAAX amino terminal protease family - - - 0.000000000000000000008825 105.0
PYH3_k127_1993701_8 CAAX protease self-immunity K07052 - - 0.00000000009221 72.0
PYH3_k127_2014472_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000141 284.0
PYH3_k127_2014472_1 - - - - 0.0000000000000000000000000000000000000000000000000000005531 209.0
PYH3_k127_2014472_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000002239 131.0
PYH3_k127_2016586_0 glycosyl transferase group 1 K00754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 400.0
PYH3_k127_2016586_1 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000001977 205.0
PYH3_k127_2016586_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000000000000000000000000000000000006657 185.0
PYH3_k127_2016586_3 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K01488 - 3.5.4.4 0.0000000000000000000000000000000000000000000000007215 188.0
PYH3_k127_2016586_4 Belongs to the BshC family K22136 - - 0.000000000000000000000000000000000000001055 166.0
PYH3_k127_2016586_5 - - - - 0.0000000000000000000000002022 116.0
PYH3_k127_2016586_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000005999 83.0
PYH3_k127_2016586_7 RDD family - - - 0.000001652 60.0
PYH3_k127_2016586_8 response to antibiotic - - - 0.0002329 50.0
PYH3_k127_2029208_0 Insulinase (Peptidase family M16) K07263 - - 0.0 1201.0
PYH3_k127_2029208_1 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006902 484.0
PYH3_k127_2029208_2 aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002454 406.0
PYH3_k127_2029208_3 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 310.0
PYH3_k127_2029208_4 - - - - 0.000000000000000008027 98.0
PYH3_k127_2055305_0 COG1104 Cysteine sulfinate desulfinase cysteine desulfurase K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 443.0
PYH3_k127_2055305_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 426.0
PYH3_k127_2055305_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000001887 99.0
PYH3_k127_2055305_11 PAP2 superfamily - - - 0.0000000000000001801 92.0
PYH3_k127_2055305_13 Domain of unknown function (DUF4339) - - - 0.0000002131 64.0
PYH3_k127_2055305_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003149 311.0
PYH3_k127_2055305_3 Cytidine monophosphokinase K00876 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009224,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0043771,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046035,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.7.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000001872 252.0
PYH3_k127_2055305_4 HpcH/HpaI aldolase/citrate lyase family K02510 - 4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000001509 228.0
PYH3_k127_2055305_5 Predicted membrane protein (DUF2142) - - - 0.0000000000000000000000000000000000000000000000000191 197.0
PYH3_k127_2055305_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.00000000000000000000000000000000000000000000001036 177.0
PYH3_k127_2055305_7 - - - - 0.000000000000000000000000000001966 140.0
PYH3_k127_2055305_8 Prephenate dehydrogenase chorismate mutase K00210 - 1.3.1.12 0.0000000000000000000000004304 116.0
PYH3_k127_2055305_9 TM2 domain - - - 0.0000000000000000000009681 110.0
PYH3_k127_2056517_0 Phosphoesterase family - - - 4.966e-195 636.0
PYH3_k127_2056517_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 617.0
PYH3_k127_2056517_2 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006719 484.0
PYH3_k127_2056517_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 362.0
PYH3_k127_2056517_4 Domain of Unknown Function (DUF1259) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 340.0
PYH3_k127_2056517_5 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009732 338.0
PYH3_k127_2056517_6 Serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001374 303.0
PYH3_k127_2056517_7 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009714 262.0
PYH3_k127_2056517_8 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000004874 171.0
PYH3_k127_2057459_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 0.0 1285.0
PYH3_k127_2057459_1 RHS protein - - - 0.00000000000000000000000000000000000000000000000000000000000000006396 258.0
PYH3_k127_2057459_2 metal-dependent phosphohydrolase, HD sub domain K03698 - - 0.00000003095 66.0
PYH3_k127_2057459_3 metal-dependent phosphohydrolase, HD sub domain K03698 - - 0.00000009015 61.0
PYH3_k127_2057459_4 Transcriptional regulator - - - 0.0000005882 63.0
PYH3_k127_2057459_5 Sigma-70, region 4 - - - 0.000007295 55.0
PYH3_k127_2057459_6 Tetratricopeptide repeat - - - 0.0002304 55.0
PYH3_k127_2057459_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0002909 51.0
PYH3_k127_2065434_0 ATPases associated with a variety of cellular activities K09689,K09691 - 3.6.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 316.0
PYH3_k127_2065434_1 Glycosyl transferases group 1 - - - 0.000000000000172 84.0
PYH3_k127_2065434_2 PKD domain - - - 0.00000001232 68.0
PYH3_k127_2066109_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004054 480.0
PYH3_k127_2066109_1 PFAM NAD-dependent epimerase dehydratase K01710,K08678 - 4.1.1.35,4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 456.0
PYH3_k127_2066109_2 Belongs to the NAD(P)-dependent epimerase dehydratase family K01784 - 5.1.3.2 0.0000113 55.0
PYH3_k127_2075600_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0000000000000000000000000000000000000000000000000000000000000000697 246.0
PYH3_k127_2075600_1 Sigma factor PP2C-like phosphatases - - - 0.000001898 59.0
PYH3_k127_2125557_0 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 321.0
PYH3_k127_2125557_1 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001423 293.0
PYH3_k127_2125557_2 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000001314 264.0
PYH3_k127_2125557_3 ABC transporter K02017 - 3.6.3.29 0.00000000000000000000000000000000000000001167 169.0
PYH3_k127_2133602_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005871 351.0
PYH3_k127_2133602_1 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 320.0
PYH3_k127_2133602_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000004424 153.0
PYH3_k127_2133602_3 Ribosomal L32p protein family K02911 - - 0.00000000000000000004646 91.0
PYH3_k127_2133602_4 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000002114 91.0
PYH3_k127_2138772_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 365.0
PYH3_k127_2138772_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006847 362.0
PYH3_k127_2138772_2 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 346.0
PYH3_k127_2138772_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000002166 233.0
PYH3_k127_2138772_4 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000001244 180.0
PYH3_k127_2138772_5 May be involved in recombinational repair of damaged DNA K03631 GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000001859 117.0
PYH3_k127_2138772_6 - - - - 0.0000000000000000007198 88.0
PYH3_k127_215189_0 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006115 256.0
PYH3_k127_215189_1 ribonuclease - - - 0.000000000000000000000000000000001165 135.0
PYH3_k127_215189_2 Barstar (barnase inhibitor) - - - 0.0000000000000000009187 96.0
PYH3_k127_215189_3 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000000000001657 79.0
PYH3_k127_215189_4 membrane protein (DUF2238) K08984 - - 0.0000000001217 63.0
PYH3_k127_215189_5 PFAM Cytochrome c, class I - - - 0.000001029 52.0
PYH3_k127_215189_6 Antitoxin component of a toxin-antitoxin (TA) module - GO:0003674,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097351,GO:1903506,GO:2000112,GO:2001141 - 0.000001297 55.0
PYH3_k127_2165039_0 signal transduction histidine kinase - - - 0.00000000000000000000003035 110.0
PYH3_k127_2165039_1 Alpha amylase, catalytic domain K01176 - 3.2.1.1 0.000000000002947 69.0
PYH3_k127_2165039_2 - - - - 0.000004199 50.0
PYH3_k127_2176224_0 spermidine synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008962 382.0
PYH3_k127_2176224_1 FAD binding domain - - - 0.0000000000000000000000001484 119.0
PYH3_k127_2176224_2 DinB superfamily - - - 0.000000000000000000000004906 111.0
PYH3_k127_2176224_3 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.000000000165 64.0
PYH3_k127_2176224_4 - - - - 0.000000002137 70.0
PYH3_k127_2248428_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 8.225e-225 727.0
PYH3_k127_2248428_1 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 453.0
PYH3_k127_2248428_10 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000000000000000003158 114.0
PYH3_k127_2248428_11 Antidote-toxin recognition MazE, bacterial antitoxin - - - 0.000000000006256 69.0
PYH3_k127_2248428_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006406 396.0
PYH3_k127_2248428_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009637 375.0
PYH3_k127_2248428_4 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 313.0
PYH3_k127_2248428_5 PFAM ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 293.0
PYH3_k127_2248428_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001699 291.0
PYH3_k127_2248428_7 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000001446 186.0
PYH3_k127_2248428_9 nucleic-acid-binding protein contains PIN domain - - - 0.0000000000000000000000000001469 123.0
PYH3_k127_2249054_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.23e-302 945.0
PYH3_k127_2249054_1 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000885 398.0
PYH3_k127_2249054_10 COGs COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1 7-dioic acid hydratase (catechol pathway) - - - 0.00000002666 55.0
PYH3_k127_2249054_11 oligosaccharyl transferase activity - - - 0.00000005499 62.0
PYH3_k127_2249054_2 PFAM Peptidase family M20 M25 M40 K01436 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 305.0
PYH3_k127_2249054_3 of the major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009938 271.0
PYH3_k127_2249054_4 Pfam:DUF59 - - - 0.0000000000000000000000000000000000000000000000576 189.0
PYH3_k127_2249054_5 Belongs to the HesB IscA family K13628 - - 0.00000000000000000000000004191 115.0
PYH3_k127_2249054_6 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K03307 - - 0.000000000000000000001769 110.0
PYH3_k127_2249054_7 Uncharacterized conserved protein (DUF2203) - - - 0.00000000000000000009817 96.0
PYH3_k127_2249054_8 Bacterial regulatory proteins, tetR family - - - 0.0000000000000001392 87.0
PYH3_k127_2249054_9 Protein of unknown function (DUF1573) - - - 0.00000000000003336 86.0
PYH3_k127_225931_0 aromatic amino acid beta-eliminating lyase threonine aldolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 427.0
PYH3_k127_225931_1 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000000001106 215.0
PYH3_k127_225931_2 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000006724 207.0
PYH3_k127_225931_3 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000007049 203.0
PYH3_k127_225931_4 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0010033,GO:0016032,GO:0016465,GO:0019058,GO:0019068,GO:0032991,GO:0035966,GO:0042221,GO:0042802,GO:0043167,GO:0043169,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051704,GO:0061077,GO:0101031,GO:1990220 - 0.0000000000001523 74.0
PYH3_k127_2271577_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000003476 227.0
PYH3_k127_2271577_1 Protein tyrosine kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018107,GO:0018193,GO:0018210,GO:0019216,GO:0019217,GO:0019222,GO:0019538,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0036211,GO:0042304,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046777,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0140096,GO:1901564 2.7.11.1 0.00000003319 65.0
PYH3_k127_2340930_0 homogentisate 12-dioxygenase K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 412.0
PYH3_k127_2340930_1 dioxygenase K00457,K16421 - 1.13.11.27,1.13.11.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009259 381.0
PYH3_k127_2340930_2 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 290.0
PYH3_k127_2340930_3 TIGRFAM Tyrosine recombinase XerD K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001032 262.0
PYH3_k127_2340930_4 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins - - - 0.0000000000000000000000000000000000000000000000000000000004337 215.0
PYH3_k127_2340930_5 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000165 198.0
PYH3_k127_2340930_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000006482 197.0
PYH3_k127_2340930_7 Bacterial antitoxin of type II TA system, VapB - - - 0.000000000000000000001119 97.0
PYH3_k127_2341584_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 341.0
PYH3_k127_2341584_1 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005415 307.0
PYH3_k127_2341584_4 PFAM peptidase M48 Ste24p - - - 0.000000002433 64.0
PYH3_k127_2349861_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008474 278.0
PYH3_k127_2349861_1 HEPN domain - - - 0.000000000000000000000000000000000002412 144.0
PYH3_k127_2349861_2 Domain of unknown function (DUF3943) - - - 0.0000000000000112 85.0
PYH3_k127_2349861_3 Nucleotidyltransferase domain - - - 0.000000000000382 77.0
PYH3_k127_2349861_4 palmitoyl-(protein) hydrolase activity K06999 - - 0.00000000005031 76.0
PYH3_k127_2349861_5 Domain of unknown function (DUF3943) - - - 0.00000001981 60.0
PYH3_k127_2349861_6 Putative regulatory protein - - - 0.000003778 58.0
PYH3_k127_2352015_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000004273 229.0
PYH3_k127_2352015_1 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000002081 121.0
PYH3_k127_2352015_2 PFAM Glycosyl transferase, group 1 - - - 0.000000000000000000000003411 110.0
PYH3_k127_2352015_3 related to Ser Thr protein kinases K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.000000000000000000004235 104.0
PYH3_k127_2352015_4 PFAM PASTA domain K01921,K08884,K12132 - 2.7.11.1,6.3.2.4 0.00000000008125 71.0
PYH3_k127_2352015_5 mttA/Hcf106 family K03116 - - 0.0000000003219 67.0
PYH3_k127_2352015_6 LysM domain - - - 0.00000007537 63.0
PYH3_k127_2352015_7 PFAM helix-turn-helix, Fis-type - - - 0.00001813 56.0
PYH3_k127_2354311_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000001388 257.0
PYH3_k127_2354311_1 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765,K02502 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000005305 206.0
PYH3_k127_2354311_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817,K04720 - 2.6.1.9,4.1.1.81 0.00000000000000000000000000000000000000008457 173.0
PYH3_k127_2354311_3 Shikimate dehydrogenase substrate binding domain K13832 - 1.1.1.25,4.2.1.10 0.000000000000000000000000000000000000001048 169.0
PYH3_k127_2354311_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000000000000002058 98.0
PYH3_k127_239128_0 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000151 280.0
PYH3_k127_239128_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000002291 241.0
PYH3_k127_2397656_0 highly regulated protein controlled by the addition removal of adenylyl groups by adenylyltransferase from specific tyrosine residues K01915 GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006536,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009314,GO:0009628,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019676,GO:0019740,GO:0019752,GO:0042802,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.2 4.635e-242 758.0
PYH3_k127_2397656_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 4.917e-219 694.0
PYH3_k127_2415234_0 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 509.0
PYH3_k127_2415234_1 Nitronate monooxygenase K00459,K02371 - 1.13.12.16,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 388.0
PYH3_k127_2415234_2 PFAM PIN domain - - - 0.0000000000000000000000000000004289 130.0
PYH3_k127_2415234_3 PFAM plasmid K06218 - - 0.0000000000000004089 80.0
PYH3_k127_2415234_4 positive regulation of growth - - - 0.00000000000002078 80.0
PYH3_k127_2415234_5 toxin-antitoxin pair type II binding K19159 - - 0.000001903 55.0
PYH3_k127_2455587_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1155.0
PYH3_k127_2455587_1 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 333.0
PYH3_k127_2455587_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000009421 235.0
PYH3_k127_2455587_3 - - - - 0.000000000000000000003285 98.0
PYH3_k127_2455587_4 Glycosyltransferase like family 2 - - - 0.00000000000000005714 94.0
PYH3_k127_2472208_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 1.056e-303 951.0
PYH3_k127_2472208_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 344.0
PYH3_k127_2472208_2 formate dehydrogenase K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005754 322.0
PYH3_k127_2472208_3 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000005003 254.0
PYH3_k127_2472208_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000001677 226.0
PYH3_k127_2472208_5 Regulatory protein - - - 0.00000000000000000519 93.0
PYH3_k127_2472208_6 formate dehydrogenase K00127 - - 0.0000000002388 71.0
PYH3_k127_2480198_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 556.0
PYH3_k127_2480198_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 490.0
PYH3_k127_2480198_2 Vault protein inter-alpha-trypsin domain K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 406.0
PYH3_k127_2480198_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000001994 185.0
PYH3_k127_2480198_4 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000002874 164.0
PYH3_k127_2480198_5 holo-[acyl-carrier-protein] synthase activity K00997,K01207 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008897,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016780,GO:0018070,GO:0018193,GO:0018209,GO:0018215,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901564,GO:1901576 2.7.8.7,3.2.1.52 0.0000000000000000000000419 104.0
PYH3_k127_2480198_6 PFAM Sensors of blue-light using FAD - - - 0.0000000000000000008694 91.0
PYH3_k127_2480198_7 acyl carrier protein - - - 0.000000001015 62.0
PYH3_k127_2480198_8 His Kinase A (phosphoacceptor) domain - - - 0.00000003752 66.0
PYH3_k127_249217_0 B12 binding domain K04034 - 1.21.98.3 3.053e-209 663.0
PYH3_k127_249217_1 radical SAM domain protein K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 555.0
PYH3_k127_2497729_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1304.0
PYH3_k127_2497729_1 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000001313 108.0
PYH3_k127_2497729_2 PIN domain - - - 0.00000000000004535 74.0
PYH3_k127_2505755_0 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 507.0
PYH3_k127_2505755_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000008046 237.0
PYH3_k127_2505755_2 ABC-2 type transporter K09690 - - 0.00000000000000000000000000000000002616 147.0
PYH3_k127_2505755_3 AsnC family - - - 0.000000000000000000000000000001245 126.0
PYH3_k127_2505755_4 Helix-turn-helix - - - 0.0000002296 59.0
PYH3_k127_2505755_5 Competence protein - - - 0.00002192 52.0
PYH3_k127_2509189_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016151,GO:0016491,GO:0022900,GO:0030288,GO:0030313,GO:0031975,GO:0032991,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0044569,GO:0045333,GO:0046872,GO:0046914,GO:0055114,GO:0071944,GO:1902494 1.12.99.6 3.232e-299 926.0
PYH3_k127_2509189_1 oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor K06282 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009897,GO:0009986,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0022900,GO:0031224,GO:0031226,GO:0031233,GO:0031237,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0048037,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944,GO:0098552,GO:0098567,GO:1902494 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 544.0
PYH3_k127_2509189_2 respiratory electron transport chain K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 320.0
PYH3_k127_2509189_3 Hydrogenase maturation protease K03605 - - 0.000000000000000000000000000000000000000004169 169.0
PYH3_k127_2509189_4 Cupin - - - 0.0000000000000000000000000000000000007001 145.0
PYH3_k127_2509189_5 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000001503 154.0
PYH3_k127_2509189_6 nickel cation binding K04651 - - 0.0000000000000000007244 91.0
PYH3_k127_2553131_0 belongs to the aldehyde dehydrogenase family K22445 - 1.2.99.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004855 347.0
PYH3_k127_2553131_1 Male sterility protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 305.0
PYH3_k127_2553131_2 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000004977 210.0
PYH3_k127_2570017_0 Prolyl oligopeptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008969 534.0
PYH3_k127_2570017_1 Carboxypeptidase regulatory-like domain - - - 0.00002077 52.0
PYH3_k127_2570047_0 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 412.0
PYH3_k127_2570047_1 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 383.0
PYH3_k127_2570047_2 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005469 312.0
PYH3_k127_2570047_3 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000004536 187.0
PYH3_k127_2570047_4 glycine decarboxylation via glycine cleavage system K02437 - - 0.0000000000000000000000000000000000000000000002183 185.0
PYH3_k127_2581026_0 Tricorn protease C1 domain K08676 - - 5.23e-303 986.0
PYH3_k127_2581026_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 438.0
PYH3_k127_2581026_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 310.0
PYH3_k127_2581026_3 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000003796 75.0
PYH3_k127_2581026_4 cellulose binding - - - 0.000003771 58.0
PYH3_k127_258205_0 Bacterial periplasmic substrate-binding proteins K02029,K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 588.0
PYH3_k127_258205_1 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 572.0
PYH3_k127_258205_2 AAA domain, putative AbiEii toxin, Type IV TA system K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000269 250.0
PYH3_k127_258205_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000000000000007497 178.0
PYH3_k127_258205_5 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045927,GO:0048518,GO:0050789,GO:0065007,GO:0071944 - 0.000000000000000002612 91.0
PYH3_k127_2667407_0 Mo-molybdopterin cofactor metabolic process K03148,K03636,K21029,K21147 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006732,GO:0006777,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008146,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016053,GO:0016740,GO:0016772,GO:0016779,GO:0016782,GO:0018130,GO:0019344,GO:0019538,GO:0019637,GO:0019720,GO:0019752,GO:0020012,GO:0030312,GO:0030682,GO:0042783,GO:0043170,GO:0043207,GO:0043436,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051810,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0061605,GO:0070566,GO:0071704,GO:0071944,GO:0075136,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.7.73,2.7.7.80,2.8.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009646 580.0
PYH3_k127_2667407_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 460.0
PYH3_k127_2667407_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 364.0
PYH3_k127_2667407_3 Pyridoxal-phosphate dependent enzyme K12339,K21148 - 2.5.1.113,2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000309 329.0
PYH3_k127_2667407_4 s cog2930 - - - 0.0000000000000000000000000000000000000000000000000000001464 206.0
PYH3_k127_2667407_5 Protein of unknown function, DUF488 - - - 0.00000000000000000000000000000000000000000000000000007141 188.0
PYH3_k127_2667407_6 ACT domain K09707 - - 0.0000000000000000000000000000000000001752 145.0
PYH3_k127_2667407_7 acetyltransferase K03789 - 2.3.1.128 0.00000000000000000000000000000000003801 139.0
PYH3_k127_2667407_8 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000001044 119.0
PYH3_k127_2667407_9 Domain of unknown function (DUF4395) - - - 0.0005947 49.0
PYH3_k127_2670500_0 Sortilin, neurotensin receptor 3, - - - 0.0 1214.0
PYH3_k127_2670500_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 630.0
PYH3_k127_2670500_10 COG0433 Predicted ATPase - - - 0.0000000000000000000000000000000003697 134.0
PYH3_k127_2670500_11 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 GO:0008150,GO:0040008,GO:0045926,GO:0048519,GO:0050789,GO:0065007 - 0.00000000000000004243 94.0
PYH3_k127_2670500_2 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 608.0
PYH3_k127_2670500_3 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005166 597.0
PYH3_k127_2670500_4 Involved in the tonB-independent uptake of proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 557.0
PYH3_k127_2670500_5 Na dependent nucleoside transporter K03317 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 386.0
PYH3_k127_2670500_6 The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate K03783 - 2.4.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 307.0
PYH3_k127_2670500_7 Dienelactone hydrolase family K01061 - 3.1.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000005135 279.0
PYH3_k127_2670500_8 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
PYH3_k127_2670500_9 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000911 174.0
PYH3_k127_2671672_0 PFAM glycosyl hydrolase BNR repeat-containing protein - - - 0.0 1140.0
PYH3_k127_2671672_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 519.0
PYH3_k127_2671672_2 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000287 243.0
PYH3_k127_2671672_3 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.000000000000000000000000003823 119.0
PYH3_k127_2671672_4 major facilitator superfamily MFS_1 - - - 0.00000000000000000000000141 108.0
PYH3_k127_2671672_5 integral membrane protein - - - 0.000000000000002676 88.0
PYH3_k127_2671672_6 Methyltransferase domain - - - 0.0000000003315 73.0
PYH3_k127_2671672_7 CopG domain protein DNA-binding domain protein - - - 0.0000000008919 62.0
PYH3_k127_2680644_0 Bacterial sugar transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000257 373.0
PYH3_k127_2680644_1 Domain of unknown function (DUF1972) K12996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 347.0
PYH3_k127_2680644_2 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000757 229.0
PYH3_k127_2680644_3 Glycosyl transferase family 2 K07011 - - 0.000000000000000000000000000000001481 143.0
PYH3_k127_2688385_0 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000002029 243.0
PYH3_k127_2688385_1 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.0000000004529 70.0
PYH3_k127_2699415_0 NmrA-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000001443 231.0
PYH3_k127_2699415_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000007308 179.0
PYH3_k127_2699415_2 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 GO:0003674,GO:0005488,GO:0005575,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0031224,GO:0033013,GO:0044237,GO:0044425,GO:0046483,GO:0046906,GO:0071704,GO:0097159,GO:1901360,GO:1901363,GO:1901564 - 0.0000000000000000000000000000000000000000009217 168.0
PYH3_k127_2699415_3 Predicted membrane protein (DUF2177) - - - 0.00000000000000000000000000000002894 130.0
PYH3_k127_2712227_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0000150,GO:0000166,GO:0000287,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008094,GO:0008144,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009432,GO:0009605,GO:0009628,GO:0009650,GO:0009987,GO:0009991,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0030145,GO:0030554,GO:0031668,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0042148,GO:0042221,GO:0042623,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046677,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071496,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 490.0
PYH3_k127_2712227_1 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000003572 226.0
PYH3_k127_2712227_2 PIN domain - - - 0.00000000000000000000000000000000000000004403 158.0
PYH3_k127_2712227_3 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000008298 111.0
PYH3_k127_2712227_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000002275 99.0
PYH3_k127_2719806_0 PFAM transposase IS116 IS110 IS902 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 487.0
PYH3_k127_2719806_1 cell wall organization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008083 313.0
PYH3_k127_2719806_2 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000003538 61.0
PYH3_k127_2729934_0 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 7.46e-212 672.0
PYH3_k127_2729934_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 473.0
PYH3_k127_2729934_10 - - - - 0.00000000000000000000000000000000000000000000000002451 188.0
PYH3_k127_2729934_11 histidine kinase dimerisation and phosphoacceptor region - - - 0.00000000000000000000000000000000000000000313 176.0
PYH3_k127_2729934_13 - - - - 0.00000000000000000000000000003961 118.0
PYH3_k127_2729934_15 nuclease activity K18828 - - 0.000000000000000000001126 102.0
PYH3_k127_2729934_2 Multicopper K06324 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 435.0
PYH3_k127_2729934_3 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 410.0
PYH3_k127_2729934_4 Involved in molybdopterin and thiamine biosynthesis, family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 391.0
PYH3_k127_2729934_5 PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001421 298.0
PYH3_k127_2729934_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001151 228.0
PYH3_k127_2729934_9 Sigma-70, region 4 type 2 - - - 0.000000000000000000000000000000000000000000000000001279 192.0
PYH3_k127_2737785_0 4Fe-4S single cluster domain K06937 - - 9.1e-241 762.0
PYH3_k127_2737785_1 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000007371 143.0
PYH3_k127_2737785_2 Belongs to the UPF0310 family - - - 0.0000000000000000000000000008627 117.0
PYH3_k127_2737785_3 Thiazole biosynthesis protein ThiG K03149 - 2.8.1.10 0.00000000000000000000000001174 121.0
PYH3_k127_2737785_4 Radical SAM-linked protein - - - 0.00000000000000002022 91.0
PYH3_k127_2737785_5 PFAM 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000001436 87.0
PYH3_k127_2784130_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 1.042e-204 658.0
PYH3_k127_2784130_1 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005662 404.0
PYH3_k127_2784130_2 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.000000000000000000000000000000000000000000000000000000000000003082 223.0
PYH3_k127_2784130_3 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.0000000000000000000000000000000000000000000000000000000003199 229.0
PYH3_k127_2784130_4 protein kinase activity K08884 - 2.7.11.1 0.000000000000000000000000000000000000000003702 162.0
PYH3_k127_2784130_5 PFAM OmpA MotB domain protein K03640 - - 0.00000000000000000000000000000000108 140.0
PYH3_k127_2784130_6 Peptidase family M23 K21472 - - 0.000000000000000000000003078 115.0
PYH3_k127_2809488_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000004468 151.0
PYH3_k127_2809488_1 Divergent polysaccharide deacetylase K09798 - - 0.000000000000000000000000000007747 136.0
PYH3_k127_2853798_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003359 300.0
PYH3_k127_2853798_1 Alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005688 280.0
PYH3_k127_2853798_2 Bacterial regulatory protein, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003188 266.0
PYH3_k127_2853798_3 Dehydrogenase K00111,K15736 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000001262 201.0
PYH3_k127_2853798_4 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000000007332 158.0
PYH3_k127_2853798_5 Tetratricopeptide repeat - - - 0.0000000000000417 81.0
PYH3_k127_2868673_0 twitching motility protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009187 509.0
PYH3_k127_2868673_1 Type II secretion system (T2SS), protein F K02455 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 458.0
PYH3_k127_2868673_2 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 435.0
PYH3_k127_2868673_3 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 439.0
PYH3_k127_2868673_4 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000004465 276.0
PYH3_k127_2868673_5 PFAM RES domain - - - 0.000000000000000000000000000000000000000000002529 170.0
PYH3_k127_2868673_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000001387 125.0
PYH3_k127_2868673_7 Protein of unknown function (DUF2384) - - - 0.000000000000000000000000003736 115.0
PYH3_k127_2868673_8 Uncharacterized ACR, COG1430 K09005 - - 0.000000000000000000646 102.0
PYH3_k127_2868673_9 SpoVT / AbrB like domain - - - 0.000000000001086 70.0
PYH3_k127_2895747_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 6.302e-258 810.0
PYH3_k127_2895747_1 response regulator - - - 1.473e-255 827.0
PYH3_k127_2895747_10 Predicted membrane protein (DUF2232) - - - 0.000000001661 67.0
PYH3_k127_2895747_2 Penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 523.0
PYH3_k127_2895747_3 Response regulator receiver modulated diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000432 529.0
PYH3_k127_2895747_4 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009019 424.0
PYH3_k127_2895747_5 transcriptional regulator K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 356.0
PYH3_k127_2895747_6 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000001301 222.0
PYH3_k127_2895747_7 nuclease activity K18828 - - 0.00000000000000000000000000000000000005539 146.0
PYH3_k127_2895747_8 binds to the 23S rRNA K02939 - - 0.0000000000000000000000000000000001554 137.0
PYH3_k127_2895747_9 - K21495 - - 0.00000000000000000006548 91.0
PYH3_k127_2897989_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 - 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006843 331.0
PYH3_k127_2897989_1 Domain of unknown function (DUF5009) - - - 0.000000000000000000000000000000000000000000000000000000000000000004918 238.0
PYH3_k127_2897989_2 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.000000000000000002226 95.0
PYH3_k127_2897989_3 - - - - 0.000000000001577 79.0
PYH3_k127_2897989_4 NmrA family - - - 0.0001486 52.0
PYH3_k127_2934774_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005657 514.0
PYH3_k127_2934774_1 glycosyl transferase - - - 0.000000000000000000000000000000000000001435 156.0
PYH3_k127_2934774_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000007754 151.0
PYH3_k127_2934774_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000001718 91.0
PYH3_k127_2934774_4 - - - - 0.000000000000002071 89.0
PYH3_k127_2940104_0 PFAM AMP-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 630.0
PYH3_k127_2940104_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 316.0
PYH3_k127_2940104_2 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001444 249.0
PYH3_k127_2940104_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000008498 136.0
PYH3_k127_2940104_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000001108 78.0
PYH3_k127_2940104_5 Multicopper oxidase K22349 - 1.16.3.3 0.00000006589 58.0
PYH3_k127_2977937_0 ABC-type multidrug transport system, ATPase and permease K06147,K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 431.0
PYH3_k127_2977937_1 Essential for recycling GMP and indirectly, cGMP K00942 GO:0003674,GO:0003824,GO:0004385,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009150,GO:0009161,GO:0009165,GO:0009167,GO:0009179,GO:0009185,GO:0009259,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0042278,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046128,GO:0046483,GO:0046710,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901657 2.7.4.8 0.0000000000000000000000000000000000000000000000000001972 192.0
PYH3_k127_2977937_2 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000002708 176.0
PYH3_k127_3002008_0 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001077 276.0
PYH3_k127_3002008_1 3'-5' exonuclease K03684 - 3.1.13.5 0.000000000000000000000000000000000000000000000000000001426 201.0
PYH3_k127_3002008_2 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000002053 128.0
PYH3_k127_3002008_3 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.000000009773 62.0
PYH3_k127_300626_0 choline dehydrogenase activity - - - 3.044e-265 824.0
PYH3_k127_300626_1 Glycogen debranching enzyme - - - 1.539e-203 668.0
PYH3_k127_300626_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 407.0
PYH3_k127_300626_3 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.00000000000000000000000000000000000000000000000000000000000000000194 236.0
PYH3_k127_300626_4 DoxX K15977 - - 0.000000000000000000000000000000000000002539 154.0
PYH3_k127_300626_5 - - - - 0.00000000000000000000000000000000001308 148.0
PYH3_k127_300626_6 Putative zinc-finger - - - 0.000000005892 62.0
PYH3_k127_3115548_0 FeS assembly protein SufB K07033,K09014 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006790,GO:0008150,GO:0008152,GO:0009536,GO:0009842,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0071840 - 1.428e-255 798.0
PYH3_k127_3115548_1 lysine biosynthetic process via aminoadipic acid - - - 1.588e-212 681.0
PYH3_k127_3115548_2 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 561.0
PYH3_k127_3115548_3 Sodium:solute symporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 411.0
PYH3_k127_3115548_4 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 366.0
PYH3_k127_3115548_5 Uncharacterized protein family (UPF0051) K09015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 352.0
PYH3_k127_3115548_6 iron-sulfur transferase activity K04488 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006807,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0010467,GO:0016740,GO:0016782,GO:0019538,GO:0019725,GO:0030003,GO:0036455,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0046916,GO:0048037,GO:0048878,GO:0050801,GO:0051536,GO:0051537,GO:0051539,GO:0051540,GO:0051604,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0097428,GO:0098771,GO:1901564 - 0.000000000000000000000000000000000000000000000002642 194.0
PYH3_k127_3115548_7 transcriptional regulator, Rrf2 family - - - 0.0000000000000000000000000000000008978 136.0
PYH3_k127_3115548_8 metal-sulfur cluster biosynthetic enzyme K02612 - - 0.000000000000000000000000000000004631 142.0
PYH3_k127_3115548_9 exonuclease activity K16899 - 3.6.4.12 0.0001023 50.0
PYH3_k127_3153558_0 Large extracellular alpha-helical protein - - - 0.0 2177.0
PYH3_k127_3153558_1 Peptidase M14, carboxypeptidase A - - - 0.0000000000000000000000000000000000000000000000000000000000000005134 235.0
PYH3_k127_3176812_0 Ribosomal protein S1 K02945,K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 578.0
PYH3_k127_3176812_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 394.0
PYH3_k127_3176812_10 - - - - 0.0001299 53.0
PYH3_k127_3176812_2 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000001611 249.0
PYH3_k127_3176812_3 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000053 240.0
PYH3_k127_3176812_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.00000000000000000000000000000000000000000000000007365 186.0
PYH3_k127_3176812_5 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K19710 GO:0003674,GO:0003824,GO:0003877,GO:0004551,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008796,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009987,GO:0015959,GO:0015961,GO:0015965,GO:0015967,GO:0016020,GO:0016462,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0040007,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0070566,GO:0071704,GO:0071944,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 2.7.7.53 0.000000000000000000000000000000000000000000007763 169.0
PYH3_k127_3176812_6 Peptidase family M50 K06402 - - 0.00000000000000000000000000000000000000000001287 177.0
PYH3_k127_3176812_7 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000005922 171.0
PYH3_k127_3176812_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000003328 148.0
PYH3_k127_3176812_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.000000000000000000000000005763 117.0
PYH3_k127_321339_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 3.169e-238 747.0
PYH3_k127_321339_1 Biotin carboxylase C-terminal domain K01941,K01961 - 6.3.4.14,6.3.4.6,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 499.0
PYH3_k127_321339_2 Peptidase U62 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000006657 139.0
PYH3_k127_321339_3 Biotin carboxyl carrier protein K01960 - 6.4.1.1 0.00000000000003479 85.0
PYH3_k127_3217450_0 Hexosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 307.0
PYH3_k127_3217450_1 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 302.0
PYH3_k127_3217450_2 Glycosyl transferase group 1 K13057 - 2.4.1.245 0.00000000000000000000000000000000000000000000001724 179.0
PYH3_k127_3217450_3 Uncharacterised nucleotidyltransferase - - - 0.0000000239 68.0
PYH3_k127_3247902_0 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000208 223.0
PYH3_k127_3247902_1 TIGRFAM polysaccharide deactylase family protein, PEP-CTERM locus subfamily - - - 0.00000000000000000000000000000000000000000001103 181.0
PYH3_k127_3247902_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000001413 171.0
PYH3_k127_3247902_3 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000026 142.0
PYH3_k127_3247902_4 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000296 130.0
PYH3_k127_3247902_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000007464 112.0
PYH3_k127_3247902_6 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000002624 96.0
PYH3_k127_3247902_7 Histidine kinase - - - 0.0000006876 61.0
PYH3_k127_3256571_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.056e-237 768.0
PYH3_k127_3256571_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002489 298.0
PYH3_k127_3256571_2 phosphorelay signal transduction system - GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003924,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006355,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0018130,GO:0019219,GO:0019222,GO:0019538,GO:0019637,GO:0019693,GO:0030312,GO:0031323,GO:0031326,GO:0032324,GO:0034641,GO:0042278,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051186,GO:0051188,GO:0051189,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0072521,GO:0080090,GO:0090407,GO:0097159,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1903506,GO:2000112,GO:2001141 - 0.0000003072 64.0
PYH3_k127_3256571_3 RDD family - - - 0.0000004051 63.0
PYH3_k127_3270778_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 494.0
PYH3_k127_3270778_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 427.0
PYH3_k127_3270778_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 396.0
PYH3_k127_3270778_3 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009903 260.0
PYH3_k127_3270778_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000003557 231.0
PYH3_k127_3270778_5 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000001533 196.0
PYH3_k127_3270778_6 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006165,GO:0006220,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044464,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:0072521,GO:0072527,GO:1901360,GO:1901564 2.7.4.6 0.000000000000000000000000000000000000000001012 160.0
PYH3_k127_3271731_0 ABC transporter K06020 - 3.6.3.25 2.365e-245 769.0
PYH3_k127_3271731_1 Prolyl oligopeptidase family - - - 1.297e-213 684.0
PYH3_k127_3271731_10 - - - - 0.0001799 49.0
PYH3_k127_3271731_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 563.0
PYH3_k127_3271731_3 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006892 517.0
PYH3_k127_3271731_4 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 327.0
PYH3_k127_3271731_5 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000882 267.0
PYH3_k127_3271731_6 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002699 270.0
PYH3_k127_3271731_7 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000003088 225.0
PYH3_k127_3271731_8 - - - - 0.00000000000000000000000000000000000000000000000000000008971 218.0
PYH3_k127_3271731_9 Belongs to the multicopper oxidase YfiH RL5 family K05810 GO:0003674,GO:0005488,GO:0005507,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000003491 130.0
PYH3_k127_3284028_0 Glycogen debranching enzyme - - - 0.0 1490.0
PYH3_k127_3284028_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1319.0
PYH3_k127_3284028_10 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000831 535.0
PYH3_k127_3284028_11 Inorganic ion transport and metabolism K03319 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000141 522.0
PYH3_k127_3284028_12 COG NOG10142 non supervised orthologous group - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008894 526.0
PYH3_k127_3284028_13 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008716 508.0
PYH3_k127_3284028_14 Polyphosphate kinase 2 (PPK2) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009564 429.0
PYH3_k127_3284028_15 EJ COG0252 L-asparaginase archaeal Glu-tRNAGln amidotransferase subunit D K01424,K05597 GO:0003674,GO:0003824,GO:0004067,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006530,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009066,GO:0009068,GO:0009987,GO:0016043,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0022607,GO:0030288,GO:0030313,GO:0031975,GO:0032787,GO:0034641,GO:0042597,GO:0042802,GO:0043436,GO:0043603,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0065003,GO:0071704,GO:0071840,GO:0072329,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.1,3.5.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004928 397.0
PYH3_k127_3284028_16 Belongs to the glutaminase family K01425 GO:0003674,GO:0003824,GO:0004359,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006541,GO:0006543,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009064,GO:0009065,GO:0009084,GO:0009987,GO:0016053,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 3.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 400.0
PYH3_k127_3284028_17 TonB dependent receptor K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 391.0
PYH3_k127_3284028_18 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 346.0
PYH3_k127_3284028_19 PFAM NAD-dependent epimerase dehydratase K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003699 323.0
PYH3_k127_3284028_2 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 5e-324 1006.0
PYH3_k127_3284028_20 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 326.0
PYH3_k127_3284028_21 Transcriptional regulator sugar kinase K00886 - 2.7.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 293.0
PYH3_k127_3284028_22 6-phosphogluconolactonase K00851,K01057 - 2.7.1.12,3.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001831 277.0
PYH3_k127_3284028_24 Phosphate-selective porin O and P K07221 - - 0.00000000000000000000000000000000000000000009474 177.0
PYH3_k127_3284028_26 YMGG-like Gly-zipper - - - 0.000000000000000000000007846 113.0
PYH3_k127_3284028_27 nuclease activity K06218 - - 0.000000000000000000001114 96.0
PYH3_k127_3284028_28 - - - - 0.0000000000000000008358 101.0
PYH3_k127_3284028_29 - - - - 0.00000000000000008308 82.0
PYH3_k127_3284028_3 Phosphoglucose isomerase K01810 - 5.3.1.9 5.93e-280 896.0
PYH3_k127_3284028_30 - - - - 0.00000000000000396 81.0
PYH3_k127_3284028_31 PFAM RNA-binding protein AU-1 Ribonuclease E G K08301 - - 0.00001091 48.0
PYH3_k127_3284028_32 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0002001 48.0
PYH3_k127_3284028_4 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 7.443e-270 839.0
PYH3_k127_3284028_5 Alpha amylase, catalytic domain - - - 8.794e-218 714.0
PYH3_k127_3284028_6 Sulfate permease family - - - 8.865e-218 693.0
PYH3_k127_3284028_7 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.94e-215 680.0
PYH3_k127_3284028_8 Fumarase C C-terminus K01744 - 4.3.1.1 3.231e-211 666.0
PYH3_k127_3284028_9 Predicted Permease Membrane Region - - - 4.881e-210 666.0
PYH3_k127_3302153_0 Aldehyde dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 477.0
PYH3_k127_3302153_1 Nucleotidyl transferase - - - 0.0000000000009878 81.0
PYH3_k127_3302153_3 OsmC-like protein - - - 0.00001959 55.0
PYH3_k127_334836_0 Transport of potassium into the cell K03549 - - 3.295e-206 670.0
PYH3_k127_334836_1 amino acid K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 563.0
PYH3_k127_334836_10 Protein of unknown function (DUF2723) - - - 0.00001622 58.0
PYH3_k127_334836_11 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.00008879 48.0
PYH3_k127_334836_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 331.0
PYH3_k127_334836_3 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 325.0
PYH3_k127_334836_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008172 279.0
PYH3_k127_334836_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000004442 260.0
PYH3_k127_334836_6 Probable RNA and SrmB- binding site of polymerase A K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000001646 288.0
PYH3_k127_334836_7 Spore Coat K01790 - 5.1.3.13 0.000000000000000000000000000000405 131.0
PYH3_k127_334836_8 Belongs to the universal stress protein A family - - - 0.0000000000000000005079 93.0
PYH3_k127_334836_9 Cytidylate kinase-like family K00945 - 2.7.4.25 0.0000000000000000006012 96.0
PYH3_k127_3351720_0 Belongs to the aldehyde dehydrogenase family K22187 - - 6.295e-219 697.0
PYH3_k127_3351720_1 Aminotransferase class-V K00812,K14260 - 2.6.1.1,2.6.1.2,2.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008289 418.0
PYH3_k127_3351720_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 308.0
PYH3_k127_3351720_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008675 267.0
PYH3_k127_3351720_4 nuclease activity - GO:0001666,GO:0003674,GO:0003824,GO:0004518,GO:0004540,GO:0006139,GO:0006417,GO:0006725,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009628,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0016070,GO:0016787,GO:0016788,GO:0017148,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0034248,GO:0034249,GO:0034641,GO:0036293,GO:0040008,GO:0043170,GO:0043207,GO:0044237,GO:0044238,GO:0044403,GO:0044419,GO:0045926,GO:0046483,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0051701,GO:0051704,GO:0051707,GO:0060255,GO:0065007,GO:0070482,GO:0071704,GO:0075136,GO:0080090,GO:0090304,GO:0090305,GO:0090501,GO:0140098,GO:1901360,GO:2000112,GO:2000113 - 0.000000000000000000000000008162 114.0
PYH3_k127_3351720_5 Polymer-forming cytoskeletal - - - 0.0000000000004351 76.0
PYH3_k127_3351720_7 - - - - 0.0000007562 61.0
PYH3_k127_335187_0 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.351e-220 706.0
PYH3_k127_335187_1 TonB-dependent Receptor Plug Domain K02014 - - 1.535e-198 644.0
PYH3_k127_335187_2 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 317.0
PYH3_k127_335187_3 glycosyl hydrolase, BNR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001695 325.0
PYH3_k127_335187_4 - - - - 0.00000000000000000000000000000000000000000000000000001767 194.0
PYH3_k127_335187_5 - - - - 0.000000000000000000000000000000000000000000001344 172.0
PYH3_k127_335187_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000001108 103.0
PYH3_k127_335187_7 lyase activity - - - 0.0000002203 63.0
PYH3_k127_3366429_0 Kdo2-lipid A biosynthetic process K02517,K22311 GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009987,GO:0016020,GO:0016740,GO:0016746,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.3.1.241,2.3.1.265 0.00000000000000000000000000000000000000000000000000000003926 214.0
PYH3_k127_3366429_1 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000002477 182.0
PYH3_k127_3366429_2 Male sterility protein - - - 0.000000000000000000000000000000000000000000003228 174.0
PYH3_k127_3366429_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000001116 171.0
PYH3_k127_3366429_4 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000005055 165.0
PYH3_k127_3366429_5 Belongs to the Fur family K09825 - - 0.0000000000000000000000000001983 119.0
PYH3_k127_3366429_6 Enoyl-CoA hydratase/isomerase K15866 - 5.3.3.18 0.000000000000004083 89.0
PYH3_k127_3366429_7 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.000000000003343 79.0
PYH3_k127_339142_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 514.0
PYH3_k127_339142_1 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005115 375.0
PYH3_k127_339142_2 ABC-type nitrate sulfonate bicarbonate transport system, permease component K02050,K15554 - - 0.0000000000000000000000000000000000000000000000000000004093 194.0
PYH3_k127_339142_3 Baseplate assembly protein - - - 0.0000000000000001093 83.0
PYH3_k127_339142_4 - - - - 0.0000000002832 65.0
PYH3_k127_3392606_0 Dehydrogenase E1 component K11381 - 1.2.4.4 2.954e-302 941.0
PYH3_k127_3392606_1 Ribosomal protein S1-like RNA-binding domain K02945 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002355 295.0
PYH3_k127_3392606_2 receptor K16092 - - 0.00000000000000000000000000000000000000000000000000000002109 222.0
PYH3_k127_3392606_3 doubled CXXCH - - - 0.00000000000000000000000000000000000000000000000000000007123 206.0
PYH3_k127_3392606_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000000002344 121.0
PYH3_k127_3392606_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000002234 83.0
PYH3_k127_3392606_6 Domain of unknown function (DUF4437) - - - 0.0000000000003222 79.0
PYH3_k127_3392606_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.0000000001065 72.0
PYH3_k127_3392606_8 - - - - 0.0000003535 63.0
PYH3_k127_3392606_9 bacterial OsmY and nodulation domain - - - 0.0004983 49.0
PYH3_k127_3478546_0 Mut7-C RNAse domain K09122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005616 271.0
PYH3_k127_3478546_1 GYD domain - - - 0.0000000000000000000001896 100.0
PYH3_k127_3478546_2 nucleotidyltransferase activity - - - 0.000000006864 63.0
PYH3_k127_3478546_3 Protein of unknown function DUF86 - - - 0.0000003273 61.0
PYH3_k127_3502480_0 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 407.0
PYH3_k127_3502480_1 Protein of unknown function DUF58 - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 297.0
PYH3_k127_3502480_2 Thioredoxin K03671 - - 0.0000000000000000000000000000000005153 138.0
PYH3_k127_3502480_3 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000004807 68.0
PYH3_k127_3502480_4 Psort location CytoplasmicMembrane, score - - - 0.000001231 61.0
PYH3_k127_3517530_0 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000004568 134.0
PYH3_k127_3517530_1 Peptidase family M20/M25/M40 K01439 - 3.5.1.18 0.000000000000000000000000000006059 139.0
PYH3_k127_3517530_2 Psort location CytoplasmicMembrane, score - - - 0.000000000000000000005715 109.0
PYH3_k127_3517530_3 Bacterial membrane protein, YfhO - - - 0.000003178 56.0
PYH3_k127_3551156_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 464.0
PYH3_k127_3551156_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004694 466.0
PYH3_k127_3551156_2 Outer membrane lipoprotein-sorting protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 353.0
PYH3_k127_3551156_3 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000009707 250.0
PYH3_k127_3551156_4 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000478 130.0
PYH3_k127_3551156_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000004409 104.0
PYH3_k127_359089_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005704 310.0
PYH3_k127_359089_1 Cyclic nucleotide-monophosphate binding domain K03316 - - 0.000000048 65.0
PYH3_k127_359089_2 Transmembrane secretion effector - - - 0.000005382 59.0
PYH3_k127_3597422_0 Bacterial regulatory protein, Fis family K13599 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 436.0
PYH3_k127_3597422_1 PFAM Formiminotransferase K00603 - 2.1.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009067 336.0
PYH3_k127_3597422_2 signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000004216 201.0
PYH3_k127_3599542_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.722e-236 751.0
PYH3_k127_3599542_1 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005535 343.0
PYH3_k127_3599542_2 SNARE associated Golgi protein K03975 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001103 283.0
PYH3_k127_3599542_3 Pilus assembly protein, PilO K02664 - - 0.00000000000000000000002353 110.0
PYH3_k127_3599542_4 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000004402 78.0
PYH3_k127_3599542_5 PFAM Fimbrial assembly family protein K02663 - - 0.000000007817 64.0
PYH3_k127_3619357_0 methionine synthase K00548 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006464,GO:0006479,GO:0006520,GO:0006555,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0008213,GO:0008270,GO:0008276,GO:0008652,GO:0008705,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0019538,GO:0019752,GO:0019842,GO:0031419,GO:0032259,GO:0034641,GO:0035999,GO:0036094,GO:0036211,GO:0042084,GO:0042558,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046872,GO:0046906,GO:0046914,GO:0048037,GO:0050667,GO:0051186,GO:0071704,GO:0097159,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.1.13 0.0 1491.0
PYH3_k127_3619357_1 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005763 289.0
PYH3_k127_3619357_2 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000001206 142.0
PYH3_k127_3703025_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 536.0
PYH3_k127_3703025_1 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 362.0
PYH3_k127_3703025_10 PFAM DivIVA family protein K04074 - - 0.000000000000001772 83.0
PYH3_k127_3703025_11 Eukaryotic integral membrane protein (DUF1751) - - - 0.0000000001596 70.0
PYH3_k127_3703025_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004183 291.0
PYH3_k127_3703025_3 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000003884 212.0
PYH3_k127_3703025_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000003585 198.0
PYH3_k127_3703025_5 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000004765 144.0
PYH3_k127_3703025_6 Ribonuclease K02226,K22316 GO:0003674,GO:0003676,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005488,GO:0006139,GO:0006401,GO:0006725,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016070,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016891,GO:0016893,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0032296,GO:0033013,GO:0033014,GO:0034641,GO:0034655,GO:0042364,GO:0042578,GO:0043170,GO:0043755,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046700,GO:0051186,GO:0051188,GO:0071667,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 3.1.26.4,3.1.3.73 0.00000000000000000000000008983 113.0
PYH3_k127_3703025_7 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000005031 96.0
PYH3_k127_3703025_8 Predicted periplasmic lipoprotein (DUF2279) - - - 0.000000000000000005894 98.0
PYH3_k127_3703025_9 C4-type zinc ribbon domain K07164 - - 0.00000000000000008751 91.0
PYH3_k127_3742587_0 GMC oxidoreductase K03333 - 1.1.3.6 8.76e-228 717.0
PYH3_k127_3742587_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 579.0
PYH3_k127_3742587_11 Putative adhesin - - - 0.0000007177 62.0
PYH3_k127_3742587_2 proline dipeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006096 520.0
PYH3_k127_3742587_3 cytochrome c peroxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 450.0
PYH3_k127_3742587_4 PFAM sodium calcium exchanger membrane region K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 419.0
PYH3_k127_3742587_5 - - - - 0.000000000000000000000000000000000000000000000005739 180.0
PYH3_k127_3742587_6 carboxylic ester hydrolase activity - - - 0.000000000000000000000000000000000000000000008713 175.0
PYH3_k127_3742587_7 Four repeated domains in the Fasciclin I family of proteins, present in many other contexts. - - - 0.00000000000000000000000000000000000000003203 158.0
PYH3_k127_3742587_8 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000002416 135.0
PYH3_k127_3750835_0 Ftsk_gamma K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005561 509.0
PYH3_k127_3750835_1 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.00000000000000000000000000000000007299 144.0
PYH3_k127_3750835_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000788 59.0
PYH3_k127_3753166_0 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01431 - 3.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 406.0
PYH3_k127_3753166_1 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004604 270.0
PYH3_k127_3753166_2 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000002998 250.0
PYH3_k127_3753166_3 electron transport chain K00347,K03614 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000599 261.0
PYH3_k127_3753166_4 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000001552 222.0
PYH3_k127_3753166_5 SMART phosphoesterase PA-phosphatase related - - - 0.0000000000000000000000000000000000000001262 169.0
PYH3_k127_3753166_6 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000005283 98.0
PYH3_k127_3753166_7 antisigma factor binding - - - 0.0000000000000000000125 96.0
PYH3_k127_3753166_8 Aspartyl protease - - - 0.0000002293 64.0
PYH3_k127_3759358_0 Secretin and TonB N terminus short domain K02666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 313.0
PYH3_k127_3759358_1 Tetratricopeptide repeat K00661,K18626 - 2.3.1.79 0.000000175 64.0
PYH3_k127_3759358_2 Prokaryotic N-terminal methylation motif - - - 0.0001665 55.0
PYH3_k127_3761635_0 AAA ATPase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 626.0
PYH3_k127_3761635_1 Adenylate cyclase - - - 0.000000000000000003374 93.0
PYH3_k127_3761635_2 Protein of unknown function (DUF2662) - - - 0.00000000000006073 80.0
PYH3_k127_3803314_0 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 6.339e-257 799.0
PYH3_k127_3803314_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 363.0
PYH3_k127_3803823_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 1193.0
PYH3_k127_3803823_1 membrane protein, TerC K05794 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 398.0
PYH3_k127_3803823_2 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 344.0
PYH3_k127_3803823_3 Gram-negative bacterial TonB protein C-terminal - - - 0.00009303 49.0
PYH3_k127_3805347_0 protein kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 308.0
PYH3_k127_3805347_1 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003035 267.0
PYH3_k127_3805347_2 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000006809 174.0
PYH3_k127_3805347_3 - - - - 0.0000000000002158 74.0
PYH3_k127_3805347_4 OsmC-like protein - - - 0.00000109 53.0
PYH3_k127_3806840_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0002790,GO:0003674,GO:0005048,GO:0005215,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006605,GO:0006612,GO:0006613,GO:0006614,GO:0006616,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009306,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0022857,GO:0022884,GO:0031224,GO:0031226,GO:0031522,GO:0032940,GO:0032978,GO:0032991,GO:0033036,GO:0033218,GO:0033365,GO:0034613,GO:0042277,GO:0042886,GO:0042887,GO:0043952,GO:0044425,GO:0044459,GO:0044464,GO:0045047,GO:0045184,GO:0046903,GO:0046907,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0061024,GO:0065002,GO:0070727,GO:0070972,GO:0071702,GO:0071705,GO:0071806,GO:0071840,GO:0071944,GO:0072594,GO:0072599,GO:0072657,GO:0090150,GO:1904680 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 595.0
PYH3_k127_3806840_1 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000016 262.0
PYH3_k127_3806840_10 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.000000000000000000000000000000131 127.0
PYH3_k127_3806840_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000004205 111.0
PYH3_k127_3806840_12 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.000000000000000000004283 96.0
PYH3_k127_3806840_13 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.000000000005419 66.0
PYH3_k127_3806840_14 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008150,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0040007,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000002101 68.0
PYH3_k127_3806840_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000003784 270.0
PYH3_k127_3806840_3 Ribosomal protein S5, C-terminal domain K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000003469 206.0
PYH3_k127_3806840_4 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000003678 194.0
PYH3_k127_3806840_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000004447 193.0
PYH3_k127_3806840_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000005171 183.0
PYH3_k127_3806840_7 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000005587 171.0
PYH3_k127_3806840_8 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000004612 156.0
PYH3_k127_3806840_9 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000004018 131.0
PYH3_k127_3814975_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008343 314.0
PYH3_k127_3814975_1 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000009787 192.0
PYH3_k127_3814975_2 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.00000000000000000000000000000007239 126.0
PYH3_k127_3814975_3 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000001406 125.0
PYH3_k127_3814975_4 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000508 89.0
PYH3_k127_383285_0 Proprotein convertase P-domain - - - 1.269e-282 888.0
PYH3_k127_383285_1 serine-type peptidase activity K01278 - 3.4.14.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 430.0
PYH3_k127_383285_2 Mur ligase family, catalytic domain K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000521 392.0
PYH3_k127_383285_3 ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 362.0
PYH3_k127_383285_4 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 324.0
PYH3_k127_383285_5 PFAM Peptidase M16 inactive domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007759 269.0
PYH3_k127_383285_6 esterase - - - 0.0000000000000000000000000000000000000000000000000000000001183 225.0
PYH3_k127_383285_7 protein kinase activity - - - 0.0000000000000000000000009196 121.0
PYH3_k127_3863197_0 Two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001159 295.0
PYH3_k127_3863197_1 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000001348 235.0
PYH3_k127_3863197_2 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000004029 180.0
PYH3_k127_3863197_3 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000004166 98.0
PYH3_k127_3863197_4 antisigma factor binding - - - 0.00000000000000000003218 94.0
PYH3_k127_3863197_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000005533 107.0
PYH3_k127_3863197_6 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000001095 61.0
PYH3_k127_3868823_0 Transketolase, pyrimidine binding domain K00167 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 430.0
PYH3_k127_3868823_1 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004159 375.0
PYH3_k127_3868823_2 Amino acid kinase family K00928 - 2.7.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 341.0
PYH3_k127_3868823_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K11381,K21416 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 325.0
PYH3_k127_3868823_4 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000001787 280.0
PYH3_k127_3868823_5 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000005319 163.0
PYH3_k127_3868823_6 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000113 134.0
PYH3_k127_3868823_7 Tetrahydrodipicolinate N-succinyltransferase N-terminal K00674 - 2.3.1.117 0.000003773 59.0
PYH3_k127_3884327_0 Mu transposase, C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 306.0
PYH3_k127_3884327_1 COG3267 Type II secretory pathway, component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000363 209.0
PYH3_k127_3884327_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000001611 104.0
PYH3_k127_3884327_3 Transposase domain (DUF772) K07487 - - 0.000000000222 69.0
PYH3_k127_3884327_4 dihydroorotate dehydrogenase activity - - - 0.00004876 49.0
PYH3_k127_389350_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 512.0
PYH3_k127_389350_1 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007305 421.0
PYH3_k127_389350_2 ABC transporter substrate-binding protein PnrA-like K07335 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003429 308.0
PYH3_k127_389350_3 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.0000000000000000000000000000000000000000000000000000000000001431 221.0
PYH3_k127_389350_4 ABC transporter K02056 - 3.6.3.17 0.000000000000000000000000000000000000000000000000008863 192.0
PYH3_k127_389350_5 KR domain K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000003963 175.0
PYH3_k127_389350_6 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000001558 157.0
PYH3_k127_3898060_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 GO:0000166,GO:0003674,GO:0003824,GO:0004107,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009423,GO:0009987,GO:0010181,GO:0016053,GO:0016829,GO:0016835,GO:0016838,GO:0019438,GO:0019752,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050662,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 377.0
PYH3_k127_3898060_1 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000001169 167.0
PYH3_k127_3902573_0 PFAM Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009691 267.0
PYH3_k127_3902573_1 Ferritin Dps family protein K03594 - 1.16.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000001778 246.0
PYH3_k127_3902573_2 acyltransferase K00655 - 2.3.1.51 0.0000000000000000000000000000000001447 141.0
PYH3_k127_3902573_3 GDP-mannose 4,6 dehydratase K01710 - 4.2.1.46 0.0000000000000000002851 87.0
PYH3_k127_3902573_4 Protein tyrosine kinase - - - 0.0000000000000002054 81.0
PYH3_k127_3902573_5 Outer membrane efflux protein - - - 0.000000000001981 78.0
PYH3_k127_3911372_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 477.0
PYH3_k127_3911372_1 PFAM peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 406.0
PYH3_k127_3911372_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate family K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000524 301.0
PYH3_k127_3911372_3 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000338 240.0
PYH3_k127_3911372_4 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000003801 153.0
PYH3_k127_3911372_5 TIGRFAM diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000001428 134.0
PYH3_k127_3911372_6 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.000000000000000139 83.0
PYH3_k127_3919440_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000004046 194.0
PYH3_k127_3919440_1 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000001384 202.0
PYH3_k127_3919440_2 PFAM thioesterase superfamily K07107 - - 0.00000000000000000000000000003253 121.0
PYH3_k127_3919440_3 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.00000000000000218 78.0
PYH3_k127_3927502_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K00187 - 1.2.7.7 7.775e-223 699.0
PYH3_k127_3927502_1 Pyruvate:ferredoxin oxidoreductase core domain II K00186 - 1.2.7.7 4.062e-208 672.0
PYH3_k127_3927502_11 metalloendopeptidase activity - - - 0.000005767 57.0
PYH3_k127_3927502_2 Cytochrome c3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 411.0
PYH3_k127_3927502_3 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002179 336.0
PYH3_k127_3927502_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 348.0
PYH3_k127_3927502_5 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001069 282.0
PYH3_k127_3927502_6 coenzyme F420 binding K07226 - - 0.0000000000000000000000000000000000000005297 157.0
PYH3_k127_3927502_7 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.0000000000000000000002669 110.0
PYH3_k127_3927502_8 SCO1/SenC K07152,K08976 - - 0.000000000000000000008799 93.0
PYH3_k127_3927502_9 Belongs to the ompA family K12216 - - 0.000000000000002084 86.0
PYH3_k127_3931438_0 cellulose binding - - - 1.595e-242 778.0
PYH3_k127_3931438_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01354 - 3.4.21.83 5.295e-214 686.0
PYH3_k127_3931438_2 unsaturated fatty acid biosynthetic process K04712 - 1.14.18.5,1.14.19.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000265 409.0
PYH3_k127_3931438_3 Zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 408.0
PYH3_k127_3931438_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000001815 212.0
PYH3_k127_3931438_5 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.00000000000000000000000000000000000000000000001938 183.0
PYH3_k127_3931438_6 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000006323 143.0
PYH3_k127_3931438_7 integral membrane protein - - - 0.00000000000000001102 92.0
PYH3_k127_3931438_8 - - - - 0.00000000000000001601 97.0
PYH3_k127_3931438_9 Protein of unknown function (DUF2752) - - - 0.00000002291 66.0
PYH3_k127_3940695_0 reductase alpha subunit K00394 - 1.8.99.2 6.019e-275 853.0
PYH3_k127_3940695_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 4.134e-232 741.0
PYH3_k127_3940695_10 nitrate reductase activity - - - 0.000000000000000000000000000000004415 143.0
PYH3_k127_3940695_11 cheY-homologous receiver domain - - - 0.0000000000000000000000000000002417 134.0
PYH3_k127_3940695_12 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000001807 124.0
PYH3_k127_3940695_13 TIGRFAM transcriptional regulator, Rrf2 family - - - 0.00000000000000000000001542 106.0
PYH3_k127_3940695_14 PFAM response regulator receiver - - - 0.0000000000000000000004486 111.0
PYH3_k127_3940695_15 Ogr/Delta-like zinc finger - - - 0.0000000000000000000029 99.0
PYH3_k127_3940695_16 transcriptional regulator - - - 0.00000000000000000009002 95.0
PYH3_k127_3940695_17 PFAM response regulator receiver - - - 0.0000000000000001634 86.0
PYH3_k127_3940695_18 PFAM Pyruvate phosphate dikinase, PEP pyruvate-binding K01007 - 2.7.9.2 0.0000000000000005831 91.0
PYH3_k127_3940695_19 PFAM response regulator receiver - - - 0.0000000000000006692 86.0
PYH3_k127_3940695_2 Belongs to the sulfate adenylyltransferase family K00958,K13811 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 597.0
PYH3_k127_3940695_20 Conserved hypothetical protein 698 - - - 0.000002114 51.0
PYH3_k127_3940695_3 response regulator, receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 428.0
PYH3_k127_3940695_4 PFAM fumarate reductase succinate dehydrogenase flavoprotein K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 407.0
PYH3_k127_3940695_5 lactate metabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 400.0
PYH3_k127_3940695_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001473 272.0
PYH3_k127_3940695_7 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002529 261.0
PYH3_k127_3940695_8 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000008116 248.0
PYH3_k127_3940695_9 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000004163 229.0
PYH3_k127_3943639_0 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 512.0
PYH3_k127_3943639_1 Reverse transcriptase (RNA-dependent DNA polymerase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 375.0
PYH3_k127_3943639_2 FAD linked oxidase domain protein K00103,K16653 GO:0000271,GO:0005575,GO:0005623,GO:0005886,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010383,GO:0016020,GO:0016051,GO:0031221,GO:0033692,GO:0034637,GO:0034645,GO:0035884,GO:0040007,GO:0042546,GO:0043170,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044464,GO:0070589,GO:0070592,GO:0071554,GO:0071704,GO:0071840,GO:0071944,GO:1901576 1.1.3.8,1.1.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 309.0
PYH3_k127_3943639_3 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000014 200.0
PYH3_k127_3943639_4 Reverse transcriptase (RNA-dependent DNA polymerase) K00986 - 2.7.7.49 0.0000000000000000000000000000000003189 133.0
PYH3_k127_3943639_5 KR domain - - - 0.00000000000000000000001076 110.0
PYH3_k127_394629_0 Phage integrase, N-terminal SAM-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 404.0
PYH3_k127_394629_1 glyoxalase bleomycin resistance protein dioxygenase K04750 - - 0.00000000000000000000000000000000000000000000000000000000198 204.0
PYH3_k127_394629_2 DinB superfamily - - - 0.00000000000000000000000000000000000000000000000005181 188.0
PYH3_k127_394629_3 COG0346 Lactoylglutathione lyase and related lyases - - - 0.000000000000000000000000000000000000000000000001668 178.0
PYH3_k127_394629_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K14161 - - 0.0000000000000000000000000000004101 133.0
PYH3_k127_3947272_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 1.071e-209 671.0
PYH3_k127_3947272_1 mRNA catabolic process K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 517.0
PYH3_k127_3947272_10 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000001507 144.0
PYH3_k127_3947272_11 O-Antigen ligase K18814 - - 0.000000000000000000000001965 117.0
PYH3_k127_3947272_12 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.00000000000000009004 81.0
PYH3_k127_3947272_13 Protein of unknown function, DUF481 K07283 - - 0.000000000003726 76.0
PYH3_k127_3947272_14 Exonuclease VII small subunit - - - 0.0000000001227 65.0
PYH3_k127_3947272_15 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000005243 66.0
PYH3_k127_3947272_16 Belongs to the UPF0434 family K09791 - - 0.00000004023 57.0
PYH3_k127_3947272_3 Phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 393.0
PYH3_k127_3947272_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 344.0
PYH3_k127_3947272_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002597 305.0
PYH3_k127_3947272_6 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005974 290.0
PYH3_k127_3947272_7 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000004689 179.0
PYH3_k127_3947272_8 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.000000000000000000000000000000000000000000000006949 180.0
PYH3_k127_3947272_9 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000004053 152.0
PYH3_k127_3949160_0 O-acetylhomoserine K01740 - 2.5.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003714 472.0
PYH3_k127_3949160_1 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000009396 261.0
PYH3_k127_3949160_2 regulation of translation K03530 - - 0.0000000000000000000000000000000006595 137.0
PYH3_k127_3966318_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008919 413.0
PYH3_k127_3966318_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000025 231.0
PYH3_k127_3966318_2 ECF sigma factor - - - 0.00000000000000000000000000000000000000000000000000000000005462 212.0
PYH3_k127_3966318_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000003887 142.0
PYH3_k127_3985252_0 6-phosphofructokinase activity K00850,K00895,K21071 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005975,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008443,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019200,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0046835,GO:0046872,GO:0047334,GO:0071704,GO:1901135 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 605.0
PYH3_k127_3985252_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 436.0
PYH3_k127_3985252_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007204 291.0
PYH3_k127_3985252_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001643 278.0
PYH3_k127_3985252_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000008149 168.0
PYH3_k127_3985252_5 NAD dependent epimerase/dehydratase family - - - 0.000000000000000000000000000000000000000001193 168.0
PYH3_k127_3985252_6 GDSL-like Lipase/Acylhydrolase - - - 0.00000000000000000000000000002668 128.0
PYH3_k127_3985252_7 Pantothenate kinase K09680 - 2.7.1.33 0.0000000000000000000000000000381 131.0
PYH3_k127_4004348_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1019.0
PYH3_k127_4004348_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 434.0
PYH3_k127_4004348_2 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 289.0
PYH3_k127_4004348_3 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000001167 240.0
PYH3_k127_4004348_4 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 GO:0003674,GO:0003824,GO:0004416,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006082,GO:0006089,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016787,GO:0016788,GO:0016790,GO:0019243,GO:0019752,GO:0032787,GO:0042180,GO:0042182,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046185,GO:0051596,GO:0061727,GO:0071704,GO:1901575,GO:1901615 3.1.2.6 0.000001995 50.0
PYH3_k127_4032727_0 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000002164 199.0
PYH3_k127_4032727_1 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000008231 156.0
PYH3_k127_4032727_2 histone H2A K63-linked ubiquitination K10914 - - 0.0000000000000000000000000000000000002758 153.0
PYH3_k127_4032727_3 RNA-binding protein containing a PIN domain K06962 - - 0.0000000000008754 74.0
PYH3_k127_4046264_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 575.0
PYH3_k127_4046264_1 PFAM EAL domain - - - 0.0000000000000000000000000000000000000000000000001884 196.0
PYH3_k127_4046264_2 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000001726 169.0
PYH3_k127_4046264_3 TIGRFAM diguanylate cyclase (GGDEF) domain - - - 0.00000000000000000000000000000001299 141.0
PYH3_k127_4046264_4 4Fe-4S binding domain - - - 0.0000000000000000000000000001441 117.0
PYH3_k127_4046264_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000008009 115.0
PYH3_k127_4046264_6 Response regulator receiver K02483,K07658,K07668 - - 0.00000000000000000001254 108.0
PYH3_k127_4059724_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1876.0
PYH3_k127_4059724_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 1791.0
PYH3_k127_4059724_10 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000005597 106.0
PYH3_k127_4059724_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1553.0
PYH3_k127_4059724_3 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07789 - - 0.0 1470.0
PYH3_k127_4059724_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 448.0
PYH3_k127_4059724_5 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 370.0
PYH3_k127_4059724_6 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001883 317.0
PYH3_k127_4059724_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000787 200.0
PYH3_k127_4059724_8 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000003661 181.0
PYH3_k127_4059724_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000001194 139.0
PYH3_k127_4132225_0 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000006669 175.0
PYH3_k127_4132225_1 serine threonine protein kinase K08884,K12132 GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0005488,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016151,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019538,GO:0032501,GO:0036211,GO:0042592,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046777,GO:0046872,GO:0046914,GO:0048871,GO:0050897,GO:0065007,GO:0065008,GO:0071704,GO:0097009,GO:0140096,GO:1901564 2.7.11.1 0.00000000000000000000000000000000000000000004455 178.0
PYH3_k127_4132225_2 Including oxidative damage repair enzymes - - - 0.0000000000000000000000000000000000000007716 154.0
PYH3_k127_413580_0 TIGRFAM drug resistance transporter, EmrB QacA subfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 589.0
PYH3_k127_413580_1 signal peptide peptidase K04773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 504.0
PYH3_k127_413580_2 radical SAM domain protein K06937 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001822 395.0
PYH3_k127_413580_3 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 307.0
PYH3_k127_413580_4 outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008572 270.0
PYH3_k127_413580_5 Protein of unknown function, DUF547 - - - 0.000000000000000000000000000000000000000000000001339 184.0
PYH3_k127_413580_6 PFAM Formylglycine-generating sulfatase enzyme K18912 - 1.14.99.50 0.00000000000000000000000000002729 131.0
PYH3_k127_413580_7 Transcriptional regulator, Crp Fnr family - - - 0.00000000000000000000000000008513 125.0
PYH3_k127_413580_8 aminopeptidase N - - - 0.00000001729 67.0
PYH3_k127_413580_9 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00001184 51.0
PYH3_k127_4137627_0 Belongs to the UPF0441 family - - - 2.575e-203 665.0
PYH3_k127_4137627_1 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 383.0
PYH3_k127_4137627_2 Zinc carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 325.0
PYH3_k127_4137627_3 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000003665 232.0
PYH3_k127_4137627_4 Domain present in ZO-1 and Unc5-like netrin receptors K10380,K21440 GO:0000278,GO:0000281,GO:0000323,GO:0000902,GO:0000904,GO:0000910,GO:0001508,GO:0002028,GO:0003008,GO:0003254,GO:0003674,GO:0005198,GO:0005200,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005764,GO:0005773,GO:0005783,GO:0005794,GO:0005829,GO:0005856,GO:0005886,GO:0005911,GO:0006810,GO:0006888,GO:0006892,GO:0006893,GO:0006928,GO:0006935,GO:0006996,GO:0007009,GO:0007010,GO:0007016,GO:0007049,GO:0007154,GO:0007275,GO:0007399,GO:0007409,GO:0007411,GO:0007528,GO:0008092,GO:0008104,GO:0008150,GO:0009605,GO:0009653,GO:0009893,GO:0009986,GO:0009987,GO:0010035,GO:0010038,GO:0010171,GO:0010256,GO:0010468,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010649,GO:0010650,GO:0010765,GO:0010959,GO:0010960,GO:0012505,GO:0014704,GO:0014731,GO:0015031,GO:0015833,GO:0016020,GO:0016043,GO:0016192,GO:0016323,GO:0016328,GO:0016528,GO:0016529,GO:0019222,GO:0019226,GO:0019228,GO:0022008,GO:0022402,GO:0022407,GO:0022409,GO:0022607,GO:0022898,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030030,GO:0030054,GO:0030154,GO:0030155,GO:0030182,GO:0030315,GO:0030424,GO:0030425,GO:0030507,GO:0030674,GO:0031175,GO:0031594,GO:0031674,GO:0032026,GO:0032386,GO:0032388,GO:0032409,GO:0032410,GO:0032411,GO:0032412,GO:0032413,GO:0032414,GO:0032501,GO:0032502,GO:0032507,GO:0032879,GO:0032880,GO:0032989,GO:0032990,GO:0033036,GO:0033157,GO:0033267,GO:0033268,GO:0033270,GO:0033563,GO:0034110,GO:0034112,GO:0034613,GO:0034762,GO:0034763,GO:0034764,GO:0034765,GO:0034766,GO:0034767,GO:0035637,GO:0036477,GO:0040008,GO:0040011,GO:0040014,GO:0040018,GO:0042221,GO:0042330,GO:0042383,GO:0042391,GO:0042592,GO:0042886,GO:0042995,GO:0043001,GO:0043005,GO:0043034,GO:0043194,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043266,GO:0043267,GO:0043269,GO:0043270,GO:0043271,GO:0043292,GO:0044085,GO:0044091,GO:0044092,GO:0044093,GO:0044291,GO:0044304,GO:0044325,GO:0044422,GO:0044424,GO:0044425,GO:0044444,GO:0044449,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0045184,GO:0045185,GO:0045202,GO:0045211,GO:0045296,GO:0045760,GO:0045785,GO:0045838,GO:0045927,GO:0046907,GO:0048193,GO:0048468,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048638,GO:0048639,GO:0048666,GO:0048667,GO:0048699,GO:0048731,GO:0048812,GO:0048856,GO:0048858,GO:0048869,GO:0048878,GO:0050789,GO:0050793,GO:0050794,GO:0050801,GO:0050808,GO:0050839,GO:0050877,GO:0050896,GO:0051049,GO:0051050,GO:0051051,GO:0051094,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051235,GO:0051239,GO:0051240,GO:0051301,GO:0051641,GO:0051649,GO:0051651,GO:0051716,GO:0055065,GO:0055080,GO:0060090,GO:0060255,GO:0060341,GO:0061024,GO:0061564,GO:0061640,GO:0061951,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070727,GO:0070887,GO:0071241,GO:0071248,GO:0071286,GO:0071702,GO:0071705,GO:0071709,GO:0071840,GO:0071944,GO:0072507,GO:0072657,GO:0072658,GO:0072659,GO:0072660,GO:0090087,GO:0090150,GO:0090313,GO:0090314,GO:0090316,GO:0097060,GO:0097447,GO:0097458,GO:0097485,GO:0098590,GO:0098771,GO:0098794,GO:0098876,GO:0098900,GO:0098901,GO:0098902,GO:0099080,GO:0099081,GO:0099512,GO:0099612,GO:0120025,GO:0120036,GO:0120038,GO:0120039,GO:1900825,GO:1900827,GO:1901016,GO:1901017,GO:1901379,GO:1901380,GO:1902259,GO:1902260,GO:1902305,GO:1902307,GO:1903047,GO:1903533,GO:1903817,GO:1903827,GO:1903829,GO:1904062,GO:1904063,GO:1904064,GO:1904181,GO:1904951,GO:1905475,GO:1905477,GO:1990778,GO:2000649,GO:2000651,GO:2001257,GO:2001258,GO:2001259 - 0.00000000000000000000009977 108.0
PYH3_k127_4137627_5 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000002209 109.0
PYH3_k127_4137627_6 - - - - 0.0000000000000000305 86.0
PYH3_k127_4137627_7 protein ubiquitination K15502 - - 0.000000000002867 79.0
PYH3_k127_4137627_9 PFAM plasmid stabilization system K06218 - - 0.0000001454 55.0
PYH3_k127_4154255_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000179 248.0
PYH3_k127_4154255_1 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000000000000000000000000000000000000000000005007 209.0
PYH3_k127_4154255_2 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.000000000000000000000000000000000000000000000000000009616 195.0
PYH3_k127_4154255_3 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000003773 195.0
PYH3_k127_4154255_4 Patatin-like phospholipase K07001 - - 0.000000000000000000000000001293 122.0
PYH3_k127_4154255_5 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000008651 94.0
PYH3_k127_4154255_6 META domain K03668 - - 0.000000000000002753 82.0
PYH3_k127_4154255_7 surface antigen variable number repeat protein K07001 - - 0.00000000002567 70.0
PYH3_k127_4154255_8 - - - - 0.000004933 49.0
PYH3_k127_4195315_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 406.0
PYH3_k127_4195315_1 Preprotein translocase subunit K03210 - - 0.00000000000000000000002042 104.0
PYH3_k127_4195315_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000008693 100.0
PYH3_k127_4195315_3 Protein of unknown function (FYDLN_acid) - - - 0.00000000001763 71.0
PYH3_k127_4195315_4 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K00950,K13940 - 2.7.6.3,4.1.2.25 0.0000001353 59.0
PYH3_k127_4272085_0 Subtilase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001588 274.0
PYH3_k127_4272085_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.0000000000000000000000000000000000000000008309 162.0
PYH3_k127_4272085_2 domain, Protein - - - 0.00000000000000000000000000000005627 142.0
PYH3_k127_4272085_3 Fungalysin metallopeptidase (M36) - - - 0.0000000000006841 83.0
PYH3_k127_4292085_0 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 356.0
PYH3_k127_4292085_1 GTP binding K06883 - - 0.00000000000000000000000000000000000000000000000000000000006903 220.0
PYH3_k127_4292085_2 Probably functions as a manganese efflux pump - - - 0.0000000000000000000000000000000000000000001809 183.0
PYH3_k127_4292085_3 Probably functions as a manganese efflux pump - - - 0.000000000000000000000000000000000000000074 173.0
PYH3_k127_4292085_4 Nuclear ribonuclease K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043628,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.000000000000000000000000000000000000002775 157.0
PYH3_k127_4292085_5 Methyltransferase - - - 0.000000000000000000000002568 114.0
PYH3_k127_4292085_6 Protein of unknown function (DUF2723) - - - 0.00001802 53.0
PYH3_k127_4329732_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 447.0
PYH3_k127_4329732_1 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000394 205.0
PYH3_k127_4329732_2 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000003079 143.0
PYH3_k127_4329732_3 Response regulator receiver domain - - - 0.00000000002965 76.0
PYH3_k127_4344908_0 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000001957 205.0
PYH3_k127_4344908_1 STAS domain K04749 - - 0.00000000000000000000000000000000007983 136.0
PYH3_k127_4344908_2 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.0000000000000000000000007364 112.0
PYH3_k127_4344908_3 Zn peptidase - - - 0.000000000000000000000002464 119.0
PYH3_k127_4345461_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1575.0
PYH3_k127_4345461_1 phosphoribosylamine-glycine ligase activity K01919 - 6.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004084 525.0
PYH3_k127_4345461_2 PFAM glycoside hydrolase, family 77 K00705 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004156 504.0
PYH3_k127_4345461_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 394.0
PYH3_k127_4345461_4 outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000003155 178.0
PYH3_k127_4345461_5 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000003927 108.0
PYH3_k127_4345461_6 Bacterial membrane protein, YfhO - - - 0.00002729 53.0
PYH3_k127_4345461_7 Type II secretion system (T2SS), protein G K02456 - - 0.0002175 52.0
PYH3_k127_4363459_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003411 413.0
PYH3_k127_4363459_1 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 358.0
PYH3_k127_4363459_2 PFAM ABC transporter K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 297.0
PYH3_k127_4363459_3 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009502 280.0
PYH3_k127_4363459_4 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000002 249.0
PYH3_k127_4363459_5 Mannose-6-phosphate isomerase - - - 0.000000000000000000000000000002297 124.0
PYH3_k127_4363459_6 COG1925 Phosphotransferase system, HPr-related proteins K08485,K11189 GO:0003674,GO:0003824,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006808,GO:0006810,GO:0008150,GO:0008152,GO:0008643,GO:0009401,GO:0009987,GO:0010033,GO:0010243,GO:0016310,GO:0016740,GO:0016772,GO:0019538,GO:0036211,GO:0042221,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050896,GO:0051179,GO:0051234,GO:0065007,GO:0071702,GO:0071704,GO:1901564,GO:1901698 - 0.0000000000000000000001925 102.0
PYH3_k127_4363459_7 PFAM PTS system fructose subfamily IIA component K02793 - 2.7.1.191 0.00000000000000000009093 104.0
PYH3_k127_4363459_8 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.00001816 55.0
PYH3_k127_4376633_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.87e-215 689.0
PYH3_k127_4376633_1 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 542.0
PYH3_k127_4376633_2 With LivFGHM is involved in the high affinity leucine transport K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 376.0
PYH3_k127_4376633_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.00000000000000000000000000000000000000000000000000000000000002497 222.0
PYH3_k127_4376633_4 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000003063 207.0
PYH3_k127_4377992_0 Sodium Bile acid symporter family K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006331 488.0
PYH3_k127_4377992_1 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 408.0
PYH3_k127_4377992_10 helix_turn_helix, Arsenical Resistance Operon Repressor K03892,K21903 - - 0.00000000000000000000000001242 113.0
PYH3_k127_4377992_11 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K08358 - - 0.0000000003479 67.0
PYH3_k127_4377992_12 thiolester hydrolase activity K06889 - - 0.0000000004168 72.0
PYH3_k127_4377992_13 Nitrate reductase delta subunit - - - 0.0000009386 59.0
PYH3_k127_4377992_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 356.0
PYH3_k127_4377992_3 response regulator K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 359.0
PYH3_k127_4377992_4 coagulation factor 5 8 type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009239 258.0
PYH3_k127_4377992_5 organic phosphonate transport K02044 - - 0.0000000000000000000000000000000000000000000000000000001052 209.0
PYH3_k127_4377992_7 AAA domain - - - 0.0000000000000000000000000000000000000000000000000005154 190.0
PYH3_k127_4377992_8 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000001323 194.0
PYH3_k127_4377992_9 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.0000000000000000000000000000000000000002889 164.0
PYH3_k127_4443833_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008535 499.0
PYH3_k127_4443833_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 387.0
PYH3_k127_4443833_2 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 303.0
PYH3_k127_4443833_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001044 282.0
PYH3_k127_4443833_4 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000006841 272.0
PYH3_k127_4443833_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000003654 177.0
PYH3_k127_4443833_6 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005618,GO:0005623,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0030312,GO:0034641,GO:0034654,GO:0040007,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.0000000000000000000000000003595 128.0
PYH3_k127_4443833_7 Glycosyltransferase Family 4 - - - 0.000006622 55.0
PYH3_k127_4501060_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 2.181e-295 930.0
PYH3_k127_4501060_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 2.83e-269 855.0
PYH3_k127_4501060_10 Polymer-forming cytoskeletal - - - 0.0000000000000000000007165 105.0
PYH3_k127_4501060_11 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.000000000000000000006354 102.0
PYH3_k127_4501060_12 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000516 91.0
PYH3_k127_4501060_13 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.000000000000000652 88.0
PYH3_k127_4501060_14 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000007346 89.0
PYH3_k127_4501060_15 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000006303 70.0
PYH3_k127_4501060_16 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.00000008603 61.0
PYH3_k127_4501060_17 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0001756 51.0
PYH3_k127_4501060_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002939 501.0
PYH3_k127_4501060_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 381.0
PYH3_k127_4501060_4 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 317.0
PYH3_k127_4501060_5 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 312.0
PYH3_k127_4501060_6 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000001611 219.0
PYH3_k127_4501060_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000002051 220.0
PYH3_k127_4501060_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000009846 205.0
PYH3_k127_4501060_9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.0000000000000000000000000000005543 136.0
PYH3_k127_4554891_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 531.0
PYH3_k127_4554891_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004448 480.0
PYH3_k127_4554891_2 Magnesium transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008623 362.0
PYH3_k127_4554891_3 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000008079 167.0
PYH3_k127_4554891_4 von Willebrand factor, type A - - - 0.000000000000000000000000000000005576 149.0
PYH3_k127_4554891_5 Peptidase M56 - - - 0.0000000000000008345 93.0
PYH3_k127_4564994_0 COG3335 Transposase and inactivated derivatives K07494 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 545.0
PYH3_k127_4564994_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 313.0
PYH3_k127_4564994_2 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.000000000000000000000000000000000000001128 153.0
PYH3_k127_4564994_3 - - - - 0.00000000000000000000000000000001767 136.0
PYH3_k127_4564994_4 DinB family - - - 0.00000000000000000000000000000006543 131.0
PYH3_k127_4564994_5 - - - - 0.0000000000000000000000000000252 122.0
PYH3_k127_462595_0 Cytochrome C assembly protein K02198 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001811 422.0
PYH3_k127_462595_1 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 342.0
PYH3_k127_462595_2 Cytochrome c assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000000002359 209.0
PYH3_k127_462595_3 PFAM cytochrome c-type biogenesis protein CcmB K02194 - - 0.00000000000000000000000000000000000000000002212 178.0
PYH3_k127_462595_4 PFAM ABC transporter related K02193 - 3.6.3.41 0.000000000000000000000000000000000000102 154.0
PYH3_k127_462595_5 Domain of unknown function (DUF374) K09778 - - 0.00000000000000000000000000000000001676 143.0
PYH3_k127_462595_6 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000001441 130.0
PYH3_k127_4707513_0 Dehydratase family K01687 - 4.2.1.9 7.612e-213 673.0
PYH3_k127_4707513_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 GO:0003674,GO:0003824,GO:0003861,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009316,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 4.2.1.33,4.2.1.35 4.979e-210 677.0
PYH3_k127_4707513_2 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.0000000000000000000000000000000000000000000000000000000000002344 237.0
PYH3_k127_4707513_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000564 219.0
PYH3_k127_4799975_0 Involved in the biosynthesis of porphyrin-containing compound K02495 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007983 424.0
PYH3_k127_4799975_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001247 404.0
PYH3_k127_4799975_2 uroporphyrinogen decarboxylase activity K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 321.0
PYH3_k127_4799975_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000791 249.0
PYH3_k127_4799975_4 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000001046 220.0
PYH3_k127_4799975_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000006338 173.0
PYH3_k127_4799975_6 ABC-type transport system involved in cytochrome c biogenesis, permease component K02497 GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008150,GO:0008152,GO:0015886,GO:0016020,GO:0044464,GO:0051179,GO:0051181,GO:0051234,GO:0055114,GO:0071702,GO:0071705,GO:0071944,GO:1901678 - 0.0000000004015 70.0
PYH3_k127_481078_0 2-oxoglutarate dehydrogenase, E1 K00164 - 1.2.4.2 0.0 1258.0
PYH3_k127_481078_1 SpoVT / AbrB like domain - - - 0.0000000000000000000000000001141 121.0
PYH3_k127_481078_2 PIN domain - - - 0.000003861 51.0
PYH3_k127_4834622_0 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002894 290.0
PYH3_k127_4834622_1 rRNA methylase K06442 - 2.1.1.226,2.1.1.227 0.000000000000000000000000000000000000000000000000000000000000000001219 248.0
PYH3_k127_4834622_2 Surface antigen variable number - - - 0.00000000000000000000000000000000000000000000000000000000000007176 245.0
PYH3_k127_4834622_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000002372 205.0
PYH3_k127_4834622_4 Glucose dehydrogenase C-terminus K00008 - 1.1.1.14 0.00000000000000000000000000002041 127.0
PYH3_k127_4834622_5 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00000001098 70.0
PYH3_k127_488208_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 7.738e-251 808.0
PYH3_k127_488208_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007632 340.0
PYH3_k127_488208_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003724 269.0
PYH3_k127_488208_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000002712 213.0
PYH3_k127_488208_4 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000002366 139.0
PYH3_k127_4892721_0 DNA topoisomerase K02470,K02622 - 5.99.1.3 7.654e-273 852.0
PYH3_k127_4892721_1 Glycosyl hydrolase family 57 K16149 - 2.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 460.0
PYH3_k127_4892721_2 - - - - 0.000000000000000000000000000000000000000733 161.0
PYH3_k127_4892721_3 Domain of unknown function (DUF4912) K09942 - - 0.00000000003537 77.0
PYH3_k127_4901837_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 549.0
PYH3_k127_4901837_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005396 284.0
PYH3_k127_4901837_2 peptidase inhibitor activity - - - 0.00000000000000000003311 104.0
PYH3_k127_4906060_0 lipopolysaccharide transport K22110 - - 0.0 1341.0
PYH3_k127_4906060_1 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 533.0
PYH3_k127_4906060_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 446.0
PYH3_k127_4906060_3 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 344.0
PYH3_k127_4906060_4 pyruvate phosphate dikinase K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006253 335.0
PYH3_k127_4906060_5 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000007636 248.0
PYH3_k127_4906060_6 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000133 196.0
PYH3_k127_4906060_7 RNA polymerase sigma factor K03088 - - 0.00000000000000000000000000000000000004606 161.0
PYH3_k127_4906060_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000001815 93.0
PYH3_k127_4906060_9 Putative zinc-finger - - - 0.00000000257 61.0
PYH3_k127_4933032_0 glutaminyl-tRNA synthetase K01886 - 6.1.1.18 4.898e-263 825.0
PYH3_k127_4933032_1 Pyridoxal-phosphate dependent enzyme K01697,K01738 - 2.5.1.47,4.2.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003617 414.0
PYH3_k127_4933032_2 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 391.0
PYH3_k127_4933032_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003108 398.0
PYH3_k127_4933032_4 PDZ DHR GLGF domain protein K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 321.0
PYH3_k127_4933032_5 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000104 166.0
PYH3_k127_4933032_6 EamA-like transporter family - - - 0.00000000000000000000000000000003939 138.0
PYH3_k127_4933032_7 VanZ like family - - - 0.00004407 57.0
PYH3_k127_4938736_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.099e-281 886.0
PYH3_k127_4938736_1 ATP-dependent peptidase activity K01338 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 583.0
PYH3_k127_4938736_10 Protein conserved in bacteria K09928 - - 0.0000001927 62.0
PYH3_k127_4938736_2 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 323.0
PYH3_k127_4938736_3 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000001896 239.0
PYH3_k127_4938736_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000001652 209.0
PYH3_k127_4938736_5 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000001781 189.0
PYH3_k127_4938736_6 glycerophosphodiester phosphodiesterase activity K01126 - 3.1.4.46 0.000000000000000000000000000000000000000001737 175.0
PYH3_k127_4938736_7 cellular component assembly - - - 0.000000000000000000000000000008347 137.0
PYH3_k127_4938736_8 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000001203 78.0
PYH3_k127_4938736_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000002469 73.0
PYH3_k127_4958126_0 PHP domain protein K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002576 422.0
PYH3_k127_4958126_1 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000001636 63.0
PYH3_k127_4958126_2 Pyruvate kinase, barrel domain K00873 - 2.7.1.40 0.0000000008822 64.0
PYH3_k127_4958126_3 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000002194 70.0
PYH3_k127_4990694_0 Branched-chain amino acid transport system / permease component K02057 - - 0.0000000000000000000000000000000000000000001801 172.0
PYH3_k127_4990694_1 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000145 121.0
PYH3_k127_4990694_2 Heavy-metal resistance - - - 0.0000000000000000008304 92.0
PYH3_k127_4990694_3 Lipopolysaccharide kinase (Kdo/WaaP) family - - - 0.000000000000003134 85.0
PYH3_k127_4990694_4 Branched-chain amino acid transport system / permease component K02057 - - 0.0004226 45.0
PYH3_k127_4996564_0 PA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 402.0
PYH3_k127_4996564_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 346.0
PYH3_k127_4996564_2 deaminase K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000887 218.0
PYH3_k127_4998381_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 559.0
PYH3_k127_4998381_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004123 407.0
PYH3_k127_4998381_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00282 GO:0001505,GO:0003674,GO:0003824,GO:0004375,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006807,GO:0008150,GO:0008152,GO:0009069,GO:0009987,GO:0016491,GO:0016638,GO:0016642,GO:0017144,GO:0019752,GO:0032991,GO:0042133,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901605,GO:1902494,GO:1990204 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009358 389.0
PYH3_k127_4998381_3 Dak2 K07030 - - 0.00000000000000000000000000000000000000000000000000009401 195.0
PYH3_k127_4998381_4 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000001323 164.0
PYH3_k127_4998381_5 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000001673 91.0
PYH3_k127_4998381_6 PFAM PEGA domain - - - 0.00001922 55.0
PYH3_k127_5015673_0 PFAM Amidase - - - 3.4e-267 829.0
PYH3_k127_5015673_1 PFAM Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 518.0
PYH3_k127_5015673_2 Beta-eliminating lyase K01667,K01668 - 4.1.99.1,4.1.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009321 518.0
PYH3_k127_5015673_3 thiosulfate sulfurtransferase activity - - - 0.000000000000000000000000000000000000000000000000000002343 204.0
PYH3_k127_5015673_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000007865 171.0
PYH3_k127_5015673_6 - - - - 0.000000000000000000000004287 107.0
PYH3_k127_5025238_0 PFAM short-chain dehydrogenase reductase SDR K15314 - - 0.0 1234.0
PYH3_k127_5025238_1 Acyl-CoA dehydrogenase, N-terminal domain - - - 0.00000000000000000000000000000000000000000000007078 173.0
PYH3_k127_5025238_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000003154 72.0
PYH3_k127_5039286_0 Seven times multi-haem cytochrome CxxCH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 497.0
PYH3_k127_5039286_1 Glycosyltransferase like family 2 K00721,K20534 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004714 357.0
PYH3_k127_5039286_2 Flavin containing amine oxidoreductase K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 345.0
PYH3_k127_5039286_3 Protein of unknown function (DUF2911) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006555 317.0
PYH3_k127_5039286_4 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000001604 207.0
PYH3_k127_5039286_5 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000006648 181.0
PYH3_k127_5039286_6 fatty acid desaturase - - - 0.00000000000425 77.0
PYH3_k127_5040948_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1641.0
PYH3_k127_5040948_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004431 335.0
PYH3_k127_5040948_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000001287 241.0
PYH3_k127_5040948_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000004805 158.0
PYH3_k127_5040948_4 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000004077 145.0
PYH3_k127_5040948_5 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000004454 109.0
PYH3_k127_5040948_6 cell wall organization - - - 0.00000000000000000002494 104.0
PYH3_k127_5040948_7 KaiC - - - 0.00000005572 65.0
PYH3_k127_5042533_0 alpha/beta hydrolase fold K07019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003897 267.0
PYH3_k127_5042533_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000008786 160.0
PYH3_k127_5042533_2 Transcriptional regulator - - - 0.00007396 54.0
PYH3_k127_5074115_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 565.0
PYH3_k127_5074115_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 465.0
PYH3_k127_5074115_2 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003378 452.0
PYH3_k127_5074115_3 quinone binding K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007013 369.0
PYH3_k127_5074115_4 formate dehydrogenase (NAD+) activity K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003374 345.0
PYH3_k127_5074115_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 317.0
PYH3_k127_5074115_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000003621 178.0
PYH3_k127_5074115_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000836 96.0
PYH3_k127_5074115_8 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000005812 98.0
PYH3_k127_5074115_9 NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008137,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000006982 76.0
PYH3_k127_5085136_0 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003926 414.0
PYH3_k127_5085136_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 357.0
PYH3_k127_5085136_2 Biotin-lipoyl like K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002984 289.0
PYH3_k127_5102238_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 602.0
PYH3_k127_5102238_1 Catalyzes the conversion of 1-proline-5-carboxylate dehydrogenase to L-glutamate K00294 - 1.2.1.88 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001983 606.0
PYH3_k127_5102238_2 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007148 444.0
PYH3_k127_5102238_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 434.0
PYH3_k127_5102238_4 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009754 381.0
PYH3_k127_5102238_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000004568 210.0
PYH3_k127_5102238_6 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000006341 123.0
PYH3_k127_5112216_0 4Fe-4S dicluster domain - - - 6.161e-205 651.0
PYH3_k127_5112216_1 TIGRFAM sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001285 550.0
PYH3_k127_5112216_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 535.0
PYH3_k127_5112216_3 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 496.0
PYH3_k127_5112216_4 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000001119 222.0
PYH3_k127_5112216_5 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000225 203.0
PYH3_k127_5120202_0 Belongs to the bacterial solute-binding protein 9 family K02077,K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008307 361.0
PYH3_k127_5120202_1 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 324.0
PYH3_k127_5120202_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001878 302.0
PYH3_k127_5120202_3 - - - - 0.0000000000000000000000000000000000000000000000001863 188.0
PYH3_k127_5120202_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000003621 156.0
PYH3_k127_5120202_5 COGs COG3093 Plasmid maintenance system antidote protein K21498 - - 0.000000000000000000008984 96.0
PYH3_k127_5120202_6 PIN domain - - - 0.0000000000000000008615 86.0
PYH3_k127_5120202_7 RelE-like toxin of type II toxin-antitoxin system HigB - - - 0.00000000000000206 79.0
PYH3_k127_5120202_8 - - - - 0.0000001152 61.0
PYH3_k127_5120202_9 Protein involved in meta-pathway of phenol degradation - - - 0.0001644 53.0
PYH3_k127_5143962_0 PAS sensor protein K13243 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008144,GO:0008150,GO:0009628,GO:0016787,GO:0016788,GO:0019825,GO:0019826,GO:0020037,GO:0036094,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0070482,GO:0071111,GO:0097159,GO:1901363 3.1.4.52 0.0 1028.0
PYH3_k127_5143962_1 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 498.0
PYH3_k127_5143962_2 beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 360.0
PYH3_k127_5143962_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000321 250.0
PYH3_k127_5143962_4 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000006621 209.0
PYH3_k127_5143962_5 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.00000000000000000000000000000000000001383 149.0
PYH3_k127_5143962_6 COG2197 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.000000000000000000000009203 117.0
PYH3_k127_5152767_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 4.586e-316 1005.0
PYH3_k127_5152767_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000189 575.0
PYH3_k127_5152767_10 Belongs to the tRNA nucleotidyltransferase poly(A) polymerase family K00970,K00974 - 2.7.7.19,2.7.7.72 0.00000000000000000000000000000000001812 158.0
PYH3_k127_5152767_11 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000007674 117.0
PYH3_k127_5152767_12 - - - - 0.0000000003366 65.0
PYH3_k127_5152767_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007547 572.0
PYH3_k127_5152767_3 Putative Na+/H+ antiporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 556.0
PYH3_k127_5152767_4 S-adenosylmethionine synthetase, C-terminal domain K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005901 539.0
PYH3_k127_5152767_5 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000255 369.0
PYH3_k127_5152767_6 Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002784 280.0
PYH3_k127_5152767_7 Permease, YjgP YjgQ - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004703 275.0
PYH3_k127_5152767_8 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000000001258 204.0
PYH3_k127_5152767_9 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000008941 184.0
PYH3_k127_5153584_0 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008516 546.0
PYH3_k127_5153584_1 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 529.0
PYH3_k127_5153584_2 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 398.0
PYH3_k127_5153584_3 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000001517 234.0
PYH3_k127_5153584_4 Heat shock protein DnaJ domain protein - - - 0.000000000000000000000000000000000000000000597 181.0
PYH3_k127_5153584_5 - - - - 0.0001171 48.0
PYH3_k127_5176801_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 394.0
PYH3_k127_5176801_1 NUDIX domain - - - 0.00000000000000000000000000000000000000001285 161.0
PYH3_k127_5176801_2 Tetratricopeptide repeat - - - 0.0000000009415 69.0
PYH3_k127_5182858_0 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000064 445.0
PYH3_k127_5182858_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008738 396.0
PYH3_k127_5182858_2 Transcription factor zinc-finger - - - 0.00000000000000000000000000575 119.0
PYH3_k127_5215119_0 Methionine synthase K00548 - 2.1.1.13 0.0 1485.0
PYH3_k127_5215119_1 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 602.0
PYH3_k127_5215119_10 Hfq protein - - - 0.00000000000000000000000002234 125.0
PYH3_k127_5215119_12 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 GO:0005575,GO:0005576 - 0.00000000000000000000000008691 114.0
PYH3_k127_5215119_13 Adenylate cyclase - - - 0.000000000000000004003 93.0
PYH3_k127_5215119_14 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) K10672,K10794 - 1.21.4.1,1.21.4.2 0.000000000000001057 79.0
PYH3_k127_5215119_15 DinB superfamily - - - 0.00000000000002011 81.0
PYH3_k127_5215119_16 Forkhead associated domain - - - 0.00000000004341 72.0
PYH3_k127_5215119_17 Lipid A 3-O-deacylase (PagL) - - - 0.00000221 58.0
PYH3_k127_5215119_18 PEGA domain - - - 0.00002855 51.0
PYH3_k127_5215119_19 Bacterial transcriptional activator domain - - - 0.0002895 52.0
PYH3_k127_5215119_2 peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008563 536.0
PYH3_k127_5215119_3 Homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 474.0
PYH3_k127_5215119_4 phosphoribosylamine-glycine ligase activity K01945,K01952,K13713 - 6.3.2.6,6.3.4.13,6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008409 445.0
PYH3_k127_5215119_5 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 360.0
PYH3_k127_5215119_8 Psort location Cytoplasmic, score - - - 0.000000000000000000000000000000000000000001319 167.0
PYH3_k127_5215119_9 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000000000000000000000088 152.0
PYH3_k127_5237163_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 7.36e-251 819.0
PYH3_k127_5237163_1 PFAM PfkB domain protein K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 315.0
PYH3_k127_5237163_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000000000000000002887 189.0
PYH3_k127_5237163_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000001496 133.0
PYH3_k127_5237163_4 Outer membrane lipoprotein - - - 0.00000000000000000000000008463 111.0
PYH3_k127_5237163_5 Lipopolysaccharide-assembly - - - 0.00000000000000004578 97.0
PYH3_k127_5237163_6 Binds directly to 16S ribosomal RNA K02968 - - 0.0000007311 57.0
PYH3_k127_5246418_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 356.0
PYH3_k127_5246418_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 339.0
PYH3_k127_5246418_2 Possible lysine decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 307.0
PYH3_k127_5246418_3 Biotin-lipoyl like K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003401 306.0
PYH3_k127_5246418_4 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.000000000000000000000000000000000000000000000000000005019 201.0
PYH3_k127_5246418_5 Zincin-like metallopeptidase - - - 0.0000000000000000000004348 109.0
PYH3_k127_5262107_0 transcription factor binding K02584 - - 7.292e-206 655.0
PYH3_k127_5262107_1 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 560.0
PYH3_k127_5262107_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 471.0
PYH3_k127_5262107_3 Dna alkylation repair - - - 0.0000000000000000000000000000000000000000000000000000000000000000001439 238.0
PYH3_k127_5262107_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000000001213 196.0
PYH3_k127_5262107_5 Integrase core domain - - - 0.00000000000000000000004076 102.0
PYH3_k127_5262107_6 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000001966 103.0
PYH3_k127_5262107_7 Peptidase family M28 K19701 - 3.4.11.10,3.4.11.6 0.00000008748 66.0
PYH3_k127_5272556_0 Participates in transcription elongation, termination and antitermination K02601 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006353,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043244,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097659,GO:1901360,GO:1901362,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000529 228.0
PYH3_k127_5272556_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000000000000000000000000000000000000000009181 174.0
PYH3_k127_5272556_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000001655 153.0
PYH3_k127_5272556_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0050518,GO:0070567 2.7.7.60 0.000000000000000000000000003097 116.0
PYH3_k127_5272556_4 Ribosomal protein L11/L12 K02867 - - 0.00000000000000000003449 90.0
PYH3_k127_5272556_5 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000002839 82.0
PYH3_k127_5272556_6 - - - - 0.00000002577 61.0
PYH3_k127_5272556_7 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000001244 57.0
PYH3_k127_5284081_0 Peptidase S46 - - - 1.696e-280 882.0
PYH3_k127_5284081_1 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000708 571.0
PYH3_k127_5284081_10 Diacylglycerol kinase catalytic domain - - - 0.00000000000000001432 95.0
PYH3_k127_5284081_11 PFAM FecR protein - - - 0.0000000001504 74.0
PYH3_k127_5284081_2 cell shape determining protein MreB K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 534.0
PYH3_k127_5284081_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 406.0
PYH3_k127_5284081_4 tRNA wobble cytosine modification - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002077 292.0
PYH3_k127_5284081_5 peptidyl-prolyl isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002063 280.0
PYH3_k127_5284081_6 Quinolinate phosphoribosyl transferase, N-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000001198 233.0
PYH3_k127_5284081_7 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000004262 164.0
PYH3_k127_5284081_8 DinB family - - - 0.00000000000000000000000000000000000000006192 173.0
PYH3_k127_5284081_9 Photosynthesis system II assembly factor YCF48 - - - 0.00000000000000000000004272 114.0
PYH3_k127_5302982_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 455.0
PYH3_k127_5302982_1 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 415.0
PYH3_k127_5348896_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 408.0
PYH3_k127_5348896_1 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.000000000000000000000000000000000000000000000000000000000506 224.0
PYH3_k127_5348896_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.0000000000000000000000000000000000000000000554 166.0
PYH3_k127_5348896_3 glycosyl transferase - - - 0.0000000000000000059 94.0
PYH3_k127_5424354_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 482.0
PYH3_k127_5424354_1 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000007816 181.0
PYH3_k127_5424354_2 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000001498 77.0
PYH3_k127_5466135_0 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008704 443.0
PYH3_k127_5466135_1 PFAM NAD dependent epimerase dehydratase family K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001909 263.0
PYH3_k127_5474507_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 588.0
PYH3_k127_5474507_1 Belongs to the aldehyde dehydrogenase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005372 541.0
PYH3_k127_5474507_2 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 501.0
PYH3_k127_5474507_3 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 317.0
PYH3_k127_5474507_4 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000003085 243.0
PYH3_k127_5474507_5 Protein of unknown function DUF86 - - - 0.00000000000000000000000000000000005321 136.0
PYH3_k127_5474507_6 PFAM Cyclic nucleotide-binding K10914,K21563 - - 0.00000000000000000000000000002483 126.0
PYH3_k127_5474507_7 PFAM CBS domain K04767 - - 0.00000000000000000000003614 116.0
PYH3_k127_5474507_8 PFAM DNA polymerase beta domain protein region K07075 - - 0.00000000000000000006483 96.0
PYH3_k127_5474736_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 2.388e-221 714.0
PYH3_k127_5474736_1 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 576.0
PYH3_k127_5474736_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006384 343.0
PYH3_k127_5474736_3 - - - - 0.0000000000000000000000000000000000000000000000001288 181.0
PYH3_k127_5474736_4 SMART serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000004413 183.0
PYH3_k127_5474736_5 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000007301 133.0
PYH3_k127_5474736_6 CBS domain - - - 0.00000000000000000009825 98.0
PYH3_k127_5474736_7 PFAM 4Fe-4S ferredoxin iron-sulfur binding - - - 0.000000000227 71.0
PYH3_k127_5525279_0 Outer membrane usher protein K07347 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 541.0
PYH3_k127_5525279_1 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 362.0
PYH3_k127_5525279_10 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000001896 143.0
PYH3_k127_5525279_11 HD domain K07814 - - 0.000000000000000000000001874 118.0
PYH3_k127_5525279_12 Spore Coat Protein - - - 0.000000000000000000000004696 108.0
PYH3_k127_5525279_13 response regulator K02481 - - 0.00000000000000000000006367 102.0
PYH3_k127_5525279_14 dinucleotide biosynthesis protein K03753 - - 0.00000000000000000003675 106.0
PYH3_k127_5525279_15 Spore Coat Protein U domain - - - 0.0000000000000000001268 98.0
PYH3_k127_5525279_16 Spore Coat Protein U domain - - - 0.0000000000000002144 93.0
PYH3_k127_5525279_17 aminotransferase class I and II - - - 0.00000000003656 71.0
PYH3_k127_5525279_18 Histidine kinase A domain protein - - - 0.0000000177 66.0
PYH3_k127_5525279_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003966 299.0
PYH3_k127_5525279_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639,K20967 - 4.1.99.22,4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002505 282.0
PYH3_k127_5525279_4 Aminotransferase class-V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007387 261.0
PYH3_k127_5525279_5 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004543 255.0
PYH3_k127_5525279_6 Probable molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000165 178.0
PYH3_k127_5525279_7 NlpE C-terminal OB domain - - - 0.000000000000000000000000000000000000000000001353 186.0
PYH3_k127_5525279_8 pilus organization K07346 - - 0.0000000000000000000000000000000000000000001798 169.0
PYH3_k127_5525279_9 haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000001716 147.0
PYH3_k127_552864_0 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 383.0
PYH3_k127_552864_1 phosphatidylethanolamine metabolic process K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 346.0
PYH3_k127_552864_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004116 280.0
PYH3_k127_552864_3 Histidine kinase HAMP - - - 0.000000000000000000000000000000000000000000009438 184.0
PYH3_k127_552864_4 NHL repeat containing protein - - - 0.000000000000000000000000000000000000001477 167.0
PYH3_k127_552864_5 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.00000000000000000000000000004541 121.0
PYH3_k127_561229_0 elongation factor G K02355 - - 8.483e-200 643.0
PYH3_k127_561229_1 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008242 284.0
PYH3_k127_561229_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000713 263.0
PYH3_k127_561229_3 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000001236 251.0
PYH3_k127_561229_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372,K16363 - 3.5.1.108,4.2.1.59 0.000000000000000000000000000000000000000000000005522 180.0
PYH3_k127_561229_5 response to nickel cation - - - 0.00000000001512 67.0
PYH3_k127_561229_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000000001742 72.0
PYH3_k127_5615525_0 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 348.0
PYH3_k127_5615525_1 SRP-dependent cotranslational protein targeting to membrane K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003018 301.0
PYH3_k127_5615525_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000001715 125.0
PYH3_k127_5615525_3 TPR repeat - - - 0.00000000000000000001741 108.0
PYH3_k127_5615525_4 Iron-containing alcohol dehydrogenase K01735 - 4.2.3.4 0.000000000000000003213 89.0
PYH3_k127_5647546_0 Drug exporters of the RND superfamily K06994,K07003,K20466,K20470 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006869,GO:0008150,GO:0009273,GO:0009987,GO:0010876,GO:0015920,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0040007,GO:0042546,GO:0044085,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0071554,GO:0071702,GO:0071766,GO:0071840,GO:0071944,GO:1901264 - 4.189e-243 792.0
PYH3_k127_5647546_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007201 304.0
PYH3_k127_5647546_2 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000007107 241.0
PYH3_k127_5647546_4 Phosphatidylserine decarboxylase - - - 0.000000000000000000000000000000000000000001454 170.0
PYH3_k127_5647546_5 S-adenosylmethionine diacylglycerol 3-amino-3-carboxypropyl transferase K13622 - - 0.0000000000003138 81.0
PYH3_k127_5647546_6 - - - - 0.0000008507 59.0
PYH3_k127_5663839_0 MobA-like NTP transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 297.0
PYH3_k127_5663839_1 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001515 277.0
PYH3_k127_5663839_2 LytTr DNA-binding domain K02477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002264 276.0
PYH3_k127_5663839_3 homoserine kinase activity K02204,K13059 - 2.7.1.162,2.7.1.39 0.000000000000000000000000000000000000000009649 164.0
PYH3_k127_5663839_4 Cell wall-active antibiotics response 4TMS YvqF - - - 0.00000000000000000000000000000000000007304 151.0
PYH3_k127_5663839_5 Male sterility protein - - - 0.00000000000004397 85.0
PYH3_k127_5664121_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 520.0
PYH3_k127_5664121_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000008568 137.0
PYH3_k127_5664121_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000003775 132.0
PYH3_k127_5680830_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 500.0
PYH3_k127_5680830_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 492.0
PYH3_k127_5680830_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 452.0
PYH3_k127_5680830_3 Domain of unknown function (DUF5011) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 302.0
PYH3_k127_5680830_4 TIGRFAM intracellular protease, PfpI family K05520 - 3.5.1.124 0.0000000000000000000000000000000000000000000000000000000000001285 215.0
PYH3_k127_5680830_6 Putative zinc- or iron-chelating domain - - - 0.000000000000007615 85.0
PYH3_k127_5680830_7 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000003975 76.0
PYH3_k127_568588_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002824 547.0
PYH3_k127_568588_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000001547 284.0
PYH3_k127_568588_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000003243 228.0
PYH3_k127_568588_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000003283 216.0
PYH3_k127_568588_4 TonB dependent receptor K02014,K16087 - - 0.00000000000000000000000000000000000000000000000000000002893 218.0
PYH3_k127_5686347_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 4.755e-262 819.0
PYH3_k127_5686347_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 605.0
PYH3_k127_5686347_3 Bacterial PH domain - - - 0.000000000000000000000000000000000000002996 160.0
PYH3_k127_5686347_4 domain, Protein - - - 0.0000000000000000000002378 96.0
PYH3_k127_5687931_0 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 430.0
PYH3_k127_5687931_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648,K18003 - 2.3.1.180,2.3.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008414 354.0
PYH3_k127_5687931_2 Smr domain - - - 0.0000000000000000000005639 98.0
PYH3_k127_580598_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.154e-202 649.0
PYH3_k127_580598_1 PFAM tRNA synthetase, class II (G, H, P and S) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 361.0
PYH3_k127_580598_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000002069 179.0
PYH3_k127_580598_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000004994 91.0
PYH3_k127_58069_0 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 432.0
PYH3_k127_58069_1 Aminotransferase class-V - - - 0.000001181 53.0
PYH3_k127_58069_2 Bacterial membrane protein, YfhO - - - 0.0001321 54.0
PYH3_k127_5842418_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003839 293.0
PYH3_k127_5842418_1 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001068 277.0
PYH3_k127_5842418_2 Belongs to the short-chain dehydrogenases reductases (SDR) family K00059,K07124 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000001074 208.0
PYH3_k127_5842418_3 repeat-containing protein - - - 0.0001924 46.0
PYH3_k127_5861459_0 NeuB family K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 335.0
PYH3_k127_5861459_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000959 240.0
PYH3_k127_5861459_2 PFAM membrane protein of K08972 - - 0.0000000000000000000000000005451 122.0
PYH3_k127_5861459_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000004137 99.0
PYH3_k127_5908013_0 PFAM FAD linked oxidase domain protein - - - 1.355e-198 634.0
PYH3_k127_5908013_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 500.0
PYH3_k127_5908013_10 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.00003569 49.0
PYH3_k127_5908013_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 GO:0003674,GO:0003824,GO:0003954,GO:0008137,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 355.0
PYH3_k127_5908013_3 aminopeptidase activity K19689 - - 0.00000000000000000000000000000000000000000000000000000000000000003288 241.0
PYH3_k127_5908013_4 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000003716 174.0
PYH3_k127_5908013_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000005159 139.0
PYH3_k127_5908013_6 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000001976 109.0
PYH3_k127_5908013_7 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000002643 63.0
PYH3_k127_5908013_8 - - - - 0.00000001397 59.0
PYH3_k127_5908013_9 Acetyltransferase (GNAT) domain - - - 0.0000201 56.0
PYH3_k127_6035229_0 4Fe-4S dicluster domain - - - 1.319e-276 857.0
PYH3_k127_6035229_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008617 527.0
PYH3_k127_6035229_2 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 318.0
PYH3_k127_6035229_3 - - - - 0.00000000000000000000000000000001484 131.0
PYH3_k127_6035229_4 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.000000000003398 79.0
PYH3_k127_6035229_5 PFAM Nitrate reductase gamma subunit - - - 0.00000001472 55.0
PYH3_k127_6122098_0 Heat shock 70 kDa protein K04043 - - 8.297e-216 685.0
PYH3_k127_6122098_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 413.0
PYH3_k127_6122098_2 DnaJ central domain K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 371.0
PYH3_k127_6122098_3 GTP binding K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000263 274.0
PYH3_k127_6122098_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000132 228.0
PYH3_k127_6122098_5 Xanthine and CO dehydrogenases maturation factor XdhC CoxF family K07402 - - 0.00000000000000000000000000000000000000000006079 173.0
PYH3_k127_6122098_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 GO:0000166,GO:0000774,GO:0001871,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0008150,GO:0009986,GO:0017076,GO:0030234,GO:0030246,GO:0030247,GO:0030554,GO:0036094,GO:0044464,GO:0050790,GO:0051082,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0097159,GO:0098772,GO:1901265,GO:1901363,GO:2001065 - 0.000000000000000000000000000001292 133.0
PYH3_k127_6122098_7 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000349 110.0
PYH3_k127_6122098_8 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000000004026 74.0
PYH3_k127_6133454_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003188 399.0
PYH3_k127_6133454_1 Tetratricopeptide repeat K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 319.0
PYH3_k127_6133454_2 PIN domain - - - 0.00000001765 61.0
PYH3_k127_6136540_0 Oligopeptide transporter OPT - - - 9.547e-229 731.0
PYH3_k127_6136540_1 PFAM peptidase T2 asparaginase 2 K01444,K13051 - 3.4.19.5,3.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 302.0
PYH3_k127_6136540_2 Bacterial regulatory proteins, tetR family K16137 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000493 259.0
PYH3_k127_6136540_3 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000299 209.0
PYH3_k127_6136540_4 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.00000000000000000000000000000000000000000001903 174.0
PYH3_k127_6136540_5 Protein of unknown function (DUF2752) - - - 0.00000000000000425 80.0
PYH3_k127_6136540_6 - - - - 0.0000000001047 69.0
PYH3_k127_614821_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 3.583e-196 616.0
PYH3_k127_614821_1 PFAM NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000001385 233.0
PYH3_k127_614821_2 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00000000000000000537 99.0
PYH3_k127_614821_3 Phospholipase D. Active site motifs. K06131 - - 0.000000000000007401 79.0
PYH3_k127_6154351_0 - - - - 0.0000000000000000000000000000000000000000000000000000000001016 208.0
PYH3_k127_6154351_1 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000003262 188.0
PYH3_k127_6154351_2 Peptidoglycan-binding domain 1 protein - - - 0.00000000000000004869 88.0
PYH3_k127_6154351_3 - - - - 0.000000000000003322 84.0
PYH3_k127_6154351_4 - - - - 0.0000000000001393 75.0
PYH3_k127_6156072_0 Tryptophan halogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 391.0
PYH3_k127_6156072_1 acetyl-CoA carboxylase, biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003596 350.0
PYH3_k127_6156072_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000132 269.0
PYH3_k127_6156072_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001092 230.0
PYH3_k127_6156072_4 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K13829 - 2.7.1.71,4.2.3.4 0.00000000000000000000000003413 122.0
PYH3_k127_6156821_0 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004452 340.0
PYH3_k127_6156821_1 exonuclease activity K16899 - 3.6.4.12 0.000000000000000000000000000001605 141.0
PYH3_k127_6165575_0 permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003674 475.0
PYH3_k127_6165575_1 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 369.0
PYH3_k127_6165575_2 PFAM NADP oxidoreductase coenzyme F420-dependent K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000004057 210.0
PYH3_k127_6165575_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000003085 201.0
PYH3_k127_6165575_4 Transcriptional regulator K03892,K21903 - - 0.0000000000000000002128 93.0
PYH3_k127_6165575_5 redox-active disulfide protein 2 - - - 0.0000000000000006564 83.0
PYH3_k127_6188059_0 PFAM peptidase M13 K07386 - - 2.877e-226 723.0
PYH3_k127_6188059_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 428.0
PYH3_k127_6188059_2 Catalyzes hydrolysis of the D-alanyl-D-alanine dipeptide K08641 - 3.4.13.22 0.0000000000000000000000000000000000000000000000000000000000000000000000001543 257.0
PYH3_k127_6188059_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009963 254.0
PYH3_k127_6188059_4 Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000002576 150.0
PYH3_k127_6188059_5 - - - - 0.000000000000000000000000000003327 134.0
PYH3_k127_6188059_6 Predicted integral membrane protein (DUF2270) - - - 0.000000000000000000000000000003599 138.0
PYH3_k127_6188059_7 Pfam:DUF3380 - - - 0.0000000002422 65.0
PYH3_k127_6188059_8 Belongs to the LOG family K06966 - 3.2.2.10 0.0000931 46.0
PYH3_k127_6207877_0 PFAM Peptidase M16 inactive domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 325.0
PYH3_k127_6207877_1 PFAM peptidase M16 domain protein - - - 0.000000000000000000000000000000000000000000000000000001935 217.0
PYH3_k127_6207877_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000002404 112.0
PYH3_k127_6215211_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 531.0
PYH3_k127_6215211_1 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 476.0
PYH3_k127_6215211_2 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 387.0
PYH3_k127_6215211_3 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 374.0
PYH3_k127_6215211_4 Hexosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007931 295.0
PYH3_k127_6215211_5 Glycosyl transferase group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000163 221.0
PYH3_k127_6215211_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000002633 207.0
PYH3_k127_6215211_7 methyltransferase K02169 - 2.1.1.197 0.00000000000000000000000000000000000000139 154.0
PYH3_k127_6220613_0 PA domain - - - 0.0 1192.0
PYH3_k127_6220613_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.081e-256 804.0
PYH3_k127_6220613_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 456.0
PYH3_k127_6220613_3 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000002852 267.0
PYH3_k127_6220613_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000001701 280.0
PYH3_k127_6220613_5 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000007512 190.0
PYH3_k127_6220613_6 PAP2 superfamily - - - 0.000000000000000265 91.0
PYH3_k127_6220613_7 S4 RNA-binding domain K04762 - - 0.000000003703 63.0
PYH3_k127_6220613_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.00000007335 54.0
PYH3_k127_6231159_0 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004663 544.0
PYH3_k127_6231159_1 radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 435.0
PYH3_k127_6231159_2 ADP-glyceromanno-heptose 6-epimerase activity K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 400.0
PYH3_k127_6235403_0 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 373.0
PYH3_k127_6235403_1 ATP-grasp domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004829 324.0
PYH3_k127_6235403_2 PAS sensor protein - - - 0.0000000000000000000000000000000000000000000000000795 186.0
PYH3_k127_6235403_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000003428 123.0
PYH3_k127_6240674_0 Large extracellular alpha-helical protein K09607 - - 2.992e-282 895.0
PYH3_k127_6240674_1 Belongs to the FPG family K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 399.0
PYH3_k127_6240674_2 Protein kinase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008616 404.0
PYH3_k127_6240674_3 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000008603 230.0
PYH3_k127_6240674_4 Pfam Secreted repeat of - - - 0.0000008413 57.0
PYH3_k127_6268258_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0001130,GO:0001131,GO:0001141,GO:0001217,GO:0002161,GO:0002196,GO:0003674,GO:0003700,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006355,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009451,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019219,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0042802,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0052689,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080090,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:0140110,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.1.1.7 8.894e-239 769.0
PYH3_k127_6268258_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K11177 - 1.17.1.4 6.354e-195 636.0
PYH3_k127_6268258_2 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 521.0
PYH3_k127_6268258_3 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000001554 271.0
PYH3_k127_6268258_4 [2Fe-2S] binding domain K03518,K13483 - 1.2.5.3 0.000000000000000000000000000000000000000000000002528 181.0
PYH3_k127_6268258_5 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000008123 151.0
PYH3_k127_6268258_6 RecX family K03565 - - 0.00000000005773 70.0
PYH3_k127_6282789_0 PFAM Type II secretion system protein E K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 346.0
PYH3_k127_6282789_1 twitching motility protein PilT K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 348.0
PYH3_k127_6282789_2 Histidine kinase - - - 0.000000000000000000000000004138 128.0
PYH3_k127_6302300_0 Belongs to the PEP-utilizing enzyme family K01007 - 2.7.9.2 0.0 1149.0
PYH3_k127_6302300_1 Carbamoyltransferase C-terminus K00612 - - 5.387e-257 807.0
PYH3_k127_6302300_2 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00262 - 1.4.1.4 4.722e-245 762.0
PYH3_k127_6302300_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 GO:0003674,GO:0003824,GO:0004352,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.2,1.4.1.3,1.4.1.4 3.563e-225 702.0
PYH3_k127_6302300_4 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 1.144e-195 621.0
PYH3_k127_6302300_5 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 544.0
PYH3_k127_6302300_6 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000425 128.0
PYH3_k127_6302300_7 Methyltransferase - - - 0.000000000002109 74.0
PYH3_k127_6315154_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 404.0
PYH3_k127_6315154_1 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 359.0
PYH3_k127_6315154_2 Parallel beta-helix repeats - - - 0.000000000106 76.0
PYH3_k127_6315154_3 - - - - 0.00006322 51.0
PYH3_k127_6318134_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 609.0
PYH3_k127_6318134_1 Leukotriene A4 hydrolase, C-terminal K01254 GO:0003674,GO:0003824,GO:0004177,GO:0004301,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006518,GO:0006629,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0008270,GO:0009056,GO:0009987,GO:0016787,GO:0016801,GO:0016803,GO:0019538,GO:0033218,GO:0034641,GO:0042277,GO:0043167,GO:0043169,GO:0043170,GO:0043171,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 3.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 534.0
PYH3_k127_6318134_10 CBS domain K04767 - - 0.000000000007055 71.0
PYH3_k127_6318134_11 response regulator - - - 0.00000000005471 70.0
PYH3_k127_6318134_12 TIGRFAM DNA binding domain protein, excisionase family - - - 0.0000000003685 64.0
PYH3_k127_6318134_13 Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain - - - 0.0000000008005 72.0
PYH3_k127_6318134_2 Domains REC, sigma54 interaction, HTH8 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 484.0
PYH3_k127_6318134_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 387.0
PYH3_k127_6318134_4 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003304 313.0
PYH3_k127_6318134_5 Domain of unknown function (DUF4010) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 297.0
PYH3_k127_6318134_6 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000000000000000000000000000000002793 190.0
PYH3_k127_6318134_7 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000001511 127.0
PYH3_k127_6318134_8 Peptidase family M28 - - - 0.000000000000000000004842 108.0
PYH3_k127_6318134_9 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000003269 94.0
PYH3_k127_6329524_0 Belongs to the argininosuccinate synthase family. Type K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 512.0
PYH3_k127_6329524_1 cleaves the gammaglutamyl linkages of compounds such as glutathione and transfer the gammaglutamyl group to other amino acids and peptides K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007153 406.0
PYH3_k127_6329524_2 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 335.0
PYH3_k127_6329524_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000006849 273.0
PYH3_k127_6329524_4 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000004696 176.0
PYH3_k127_6329524_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000002967 139.0
PYH3_k127_6329524_6 Regulates arginine biosynthesis genes K03402 - - 0.0000000000000000000013 101.0
PYH3_k127_6329524_7 - - - - 0.00008226 45.0
PYH3_k127_6329524_8 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0002875 51.0
PYH3_k127_6347470_0 Uncharacterized membrane protein (DUF2298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 593.0
PYH3_k127_6347470_1 Patatin-like phospholipase - - - 0.000000000000000000000000000000000000000000000000000000000000003667 240.0
PYH3_k127_6347470_2 PFAM Alpha beta hydrolase K07019 - - 0.000000000000000000000000000000000000000000000000000000000002138 241.0
PYH3_k127_6347470_3 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000000000000000000000002604 198.0
PYH3_k127_6347470_4 PFAM helix-turn-helix- domain containing protein AraC type - - - 0.0003823 50.0
PYH3_k127_636905_0 Phosphate transporter family K03306 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 431.0
PYH3_k127_636905_1 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000007402 261.0
PYH3_k127_636905_2 Protein of unknown function DUF47 K02039,K07220 - - 0.00000000000000000000000000000000000000000000000000366 191.0
PYH3_k127_6373754_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 9.586e-284 901.0
PYH3_k127_6373754_1 Polysulphide reductase, NrfD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007555 579.0
PYH3_k127_6373754_10 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000005378 227.0
PYH3_k127_6373754_11 Appr-1'-p processing enzyme - - - 0.00000000000000000000000000000000000000000000000000000002146 203.0
PYH3_k127_6373754_12 YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase, but does not seem to catalyze any of the K09780 - - 0.0000000000000000000000000000000000000006244 150.0
PYH3_k127_6373754_13 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000006973 164.0
PYH3_k127_6373754_14 - - - - 0.000000000000000000000000000000006623 137.0
PYH3_k127_6373754_15 DinB family - - - 0.00000000000000000000000000000000726 134.0
PYH3_k127_6373754_16 - - - - 0.0000000000000000000000000000006505 140.0
PYH3_k127_6373754_17 Cytochrome c554 and c-prime - - - 0.00000000000000000000000001522 120.0
PYH3_k127_6373754_18 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000008645 113.0
PYH3_k127_6373754_2 Molydopterin dinucleotide binding domain K08352 - 1.8.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 477.0
PYH3_k127_6373754_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K13252 - 2.1.3.3,2.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 457.0
PYH3_k127_6373754_4 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 424.0
PYH3_k127_6373754_5 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002643 351.0
PYH3_k127_6373754_6 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005332 338.0
PYH3_k127_6373754_7 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 337.0
PYH3_k127_6373754_8 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 317.0
PYH3_k127_6373754_9 Cytochrome c K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000043 297.0
PYH3_k127_6374864_0 Belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 2.234e-230 738.0
PYH3_k127_6374864_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 432.0
PYH3_k127_6374864_10 AbrB family - - - 0.0002532 48.0
PYH3_k127_6374864_2 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 392.0
PYH3_k127_6374864_3 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002864 392.0
PYH3_k127_6374864_4 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 309.0
PYH3_k127_6374864_5 Belongs to the peptidase S16 family - - - 0.0000000000000000000000000000000000000005919 153.0
PYH3_k127_6374864_6 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000004731 161.0
PYH3_k127_6374864_7 Roadblock/LC7 domain - - - 0.000000000000000001901 86.0
PYH3_k127_6374864_8 PIN domain - - - 0.000000000000007002 81.0
PYH3_k127_6374864_9 - - - - 0.000000000007941 77.0
PYH3_k127_6385994_0 ATPases associated with a variety of cellular activities K01990,K09689,K09691,K09693 - 3.6.3.38,3.6.3.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 359.0
PYH3_k127_6385994_1 Carboxypeptidase regulatory-like domain - - - 0.0000000000007321 74.0
PYH3_k127_6385994_2 Carboxypeptidase regulatory-like domain - - - 0.0000002071 58.0
PYH3_k127_6394038_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002512 581.0
PYH3_k127_6394038_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001654 303.0
PYH3_k127_6394038_2 required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0002949,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.7.87 0.000000000000000000000000000000000000000000000000000000000000000000000003899 255.0
PYH3_k127_6394038_3 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000001175 137.0
PYH3_k127_6394038_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000002062 118.0
PYH3_k127_6394038_5 Plasmid stability protein - - - 0.0000007448 53.0
PYH3_k127_6399058_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1627.0
PYH3_k127_6399058_1 Multicopper oxidase K06324 - 1.16.3.3 4.099e-221 712.0
PYH3_k127_6399058_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 391.0
PYH3_k127_6399058_3 Lytic murein transglycosylase K08309 - - 0.00000000000000000000005274 110.0
PYH3_k127_6466827_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 1.699e-232 737.0
PYH3_k127_6466827_1 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01667,K01668 - 4.1.99.1,4.1.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 604.0
PYH3_k127_6466827_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 526.0
PYH3_k127_6466827_3 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 409.0
PYH3_k127_6466827_4 Insulinase (Peptidase family M16) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002125 272.0
PYH3_k127_6466827_5 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000001759 243.0
PYH3_k127_6466827_6 Stage II sporulation protein K06381 - - 0.0000000000000000000001763 107.0
PYH3_k127_6486412_0 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 7.331e-299 919.0
PYH3_k127_6486412_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 2.156e-295 923.0
PYH3_k127_6486412_10 Histidine kinase - - - 0.000006251 56.0
PYH3_k127_6486412_2 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 2.812e-224 702.0
PYH3_k127_6486412_3 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000945 607.0
PYH3_k127_6486412_4 PFAM Rieske 2Fe-2S domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005103 276.0
PYH3_k127_6486412_5 Cytochrome C oxidase subunit II, periplasmic domain K00376 - 1.7.2.4 0.0000000000000000000000000000000000000000000000001475 179.0
PYH3_k127_6486412_6 PFAM ATP-binding region, ATPase domain protein K02668,K07708,K07709 - 2.7.13.3 0.0000000000000000000000000000001323 129.0
PYH3_k127_6486412_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000008955 91.0
PYH3_k127_6486412_8 response regulator - - - 0.0000000003381 69.0
PYH3_k127_6486412_9 DNA binding - - - 0.0000000008497 64.0
PYH3_k127_6495861_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 515.0
PYH3_k127_6495861_1 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 418.0
PYH3_k127_6495861_2 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 329.0
PYH3_k127_6495861_3 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 335.0
PYH3_k127_6495861_4 Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003434 322.0
PYH3_k127_6495861_5 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000001053 196.0
PYH3_k127_6495861_7 PAP2 superfamily - - - 0.00000000000000000000002184 104.0
PYH3_k127_6495861_8 RNA 2'-O ribose methyltransferase substrate binding K03437 - - 0.000000000000004294 84.0
PYH3_k127_6526088_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003442 321.0
PYH3_k127_6526088_1 histidine kinase HAMP region domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004616 277.0
PYH3_k127_6526088_2 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000005134 235.0
PYH3_k127_6526088_3 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000000000000000000000000000000000000000002926 172.0
PYH3_k127_6526088_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000001098 172.0
PYH3_k127_6548214_0 SNF2 family N-terminal domain - - - 1.71e-206 668.0
PYH3_k127_6548214_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 331.0
PYH3_k127_6548214_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07714 - - 0.00000000000000000000000000000000000000000000000000000001095 216.0
PYH3_k127_6548214_3 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000001318 147.0
PYH3_k127_6548214_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000001328 119.0
PYH3_k127_6548214_5 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000008124 104.0
PYH3_k127_6548214_6 Swim zinc finger - - - 0.00000000000003344 87.0
PYH3_k127_6577804_0 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 554.0
PYH3_k127_6577804_1 Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II - - - 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
PYH3_k127_6577804_2 Mitochondrial biogenesis AIM24 - - - 0.000000000214 73.0
PYH3_k127_6610137_0 Protein tyrosine kinase K08282,K12132 - 2.7.11.1 0.0 1060.0
PYH3_k127_6610137_1 Glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 8.435e-249 778.0
PYH3_k127_6610137_2 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004994 329.0
PYH3_k127_6610137_3 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000009881 218.0
PYH3_k127_6610137_4 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000112 192.0
PYH3_k127_6617729_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 391.0
PYH3_k127_6617729_1 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 340.0
PYH3_k127_6617729_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 343.0
PYH3_k127_6617729_3 Belongs to the SEDS family K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000163 304.0
PYH3_k127_6617729_4 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000003838 101.0
PYH3_k127_6645302_0 chlorophyll binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001156 260.0
PYH3_k127_6645302_1 carboxylic ester hydrolase activity - - - 0.00000000000000000000000000000000000000000000000000001109 201.0
PYH3_k127_6645302_3 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000000000002832 94.0
PYH3_k127_6645302_4 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.000000000000006773 74.0
PYH3_k127_6645302_5 - - - - 0.00000067 61.0
PYH3_k127_6645302_6 toxin-antitoxin pair type II binding K19159 - - 0.00005135 49.0
PYH3_k127_6645302_7 'glutamate synthase K00266 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.4.1.13,1.4.1.14 0.00007285 51.0
PYH3_k127_6673761_0 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 545.0
PYH3_k127_6673761_1 Putative modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 468.0
PYH3_k127_6673761_10 Domain of unknown function (DUF4437) - - - 0.000000001052 71.0
PYH3_k127_6673761_11 L-carnitine dehydratase bile acid-inducible protein F - - - 0.0000004108 57.0
PYH3_k127_6673761_12 PFAM Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.00002915 54.0
PYH3_k127_6673761_13 - - - - 0.0005555 44.0
PYH3_k127_6673761_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003902 441.0
PYH3_k127_6673761_3 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 396.0
PYH3_k127_6673761_4 TIGRFAM Methylglyoxal synthase K01734 - 4.2.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000007302 245.0
PYH3_k127_6673761_5 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000001914 243.0
PYH3_k127_6673761_6 NTPase - - - 0.000000000000000000000000000000000000000001496 161.0
PYH3_k127_6673761_7 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000007069 117.0
PYH3_k127_6673761_8 conserved protein (COG2071) K09166 - - 0.00000000000000287 76.0
PYH3_k127_6673761_9 - - - - 0.0000000002642 66.0
PYH3_k127_6753240_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 463.0
PYH3_k127_6753240_1 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.0000000000000000000000000000000000000000000000000000005568 203.0
PYH3_k127_6753240_2 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000009554 201.0
PYH3_k127_6753240_3 Surface antigen - - - 0.00000000000000000000000000000000000000000000006439 179.0
PYH3_k127_6753240_4 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000002559 144.0
PYH3_k127_6753240_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.0000000000000000000000000000002903 138.0
PYH3_k127_6753240_6 nucleic acid-binding protein contains PIN domain - - - 0.0000000000000000000000000008165 126.0
PYH3_k127_6753240_7 - - - - 0.00000000000000000001773 98.0
PYH3_k127_6753240_8 - K05807 - - 0.00000000000003619 83.0
PYH3_k127_6753240_9 - K21495 - - 0.0003248 47.0
PYH3_k127_676199_0 Peptide transporter - - - 2.694e-212 679.0
PYH3_k127_676199_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005697 581.0
PYH3_k127_676199_2 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000007308 142.0
PYH3_k127_676199_3 homoserine transmembrane transporter activity K06600,K06895 - - 0.0000000000000000000000002526 110.0
PYH3_k127_6765186_0 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 4.837e-214 671.0
PYH3_k127_6765186_1 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 407.0
PYH3_k127_6765186_2 - - - - 0.0000000000000000000000009756 115.0
PYH3_k127_6765186_3 COG1595 DNA-directed RNA polymerase specialized sigma subunit sigma24 homolog K03088 - - 0.000000002886 62.0
PYH3_k127_6787310_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 6.376e-232 729.0
PYH3_k127_6787310_1 Acetolactate synthase K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003301 563.0
PYH3_k127_6787310_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006162 484.0
PYH3_k127_6787310_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 434.0
PYH3_k127_6787310_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007635 383.0
PYH3_k127_6787310_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 314.0
PYH3_k127_6787310_6 ACT domain K01653 - 2.2.1.6 0.0000003193 56.0
PYH3_k127_6787310_7 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.000001164 51.0
PYH3_k127_6806419_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1060.0
PYH3_k127_6806419_1 Cytochrome b(N-terminal)/b6/petB K00410,K00412,K02635,K02637 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 349.0
PYH3_k127_6806419_2 PFAM peptidase M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 312.0
PYH3_k127_6806419_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000001873 172.0
PYH3_k127_6806419_4 Rieske [2Fe-2S] domain K00411,K02636,K03886 - 1.10.2.2,1.10.9.1 0.000000000000000000002097 106.0
PYH3_k127_6806419_5 Protein of unknown function (DUF2892) - - - 0.0000000000000000002115 96.0
PYH3_k127_6806419_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000000003127 96.0
PYH3_k127_6806419_7 TIGRFAM regulatory protein, FmdB - - - 0.00000005421 60.0
PYH3_k127_6816427_0 Large extracellular alpha-helical protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004889 597.0
PYH3_k127_6816427_1 Cys/Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 411.0
PYH3_k127_6816427_2 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001117 356.0
PYH3_k127_6816427_3 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 345.0
PYH3_k127_6816427_4 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001405 303.0
PYH3_k127_6816427_5 Cytochrome c7 and related cytochrome c K19405,K19411 GO:0003674,GO:0005488,GO:0005507,GO:0006950,GO:0008150,GO:0008270,GO:0010035,GO:0010038,GO:0042221,GO:0043167,GO:0043169,GO:0046686,GO:0046688,GO:0046870,GO:0046872,GO:0046914,GO:0050896,GO:0050897,GO:0097501,GO:1990169,GO:1990170 2.7.14.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 292.0
PYH3_k127_6870967_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 467.0
PYH3_k127_6870967_1 Protein of unknown function DUF86 - - - 0.0000000000000000000000002071 113.0
PYH3_k127_6870967_2 Domain of unknown function (DUF4126) - - - 0.0000000000000000004531 102.0
PYH3_k127_6870967_3 PFAM DNA polymerase beta domain protein region K07075 - - 0.00000000000002356 79.0
PYH3_k127_6870967_4 heat shock protein binding K05516,K05801 - - 0.00001043 58.0
PYH3_k127_6896187_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 493.0
PYH3_k127_6896187_1 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 396.0
PYH3_k127_6896187_10 nuclear chromosome segregation - - - 0.000000000000003334 86.0
PYH3_k127_6896187_11 O-methyltransferase K00588 - 2.1.1.104 0.00000000000001213 81.0
PYH3_k127_6896187_12 O-methyltransferase K00588 - 2.1.1.104 0.000000000421 66.0
PYH3_k127_6896187_13 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.00027 48.0
PYH3_k127_6896187_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 323.0
PYH3_k127_6896187_3 microcin C7 resistance K01297 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007563 285.0
PYH3_k127_6896187_4 O-methyltransferase K00588 - 2.1.1.104 0.000000000000000000000000000000000000000000000000000000000000000000003534 254.0
PYH3_k127_6896187_5 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000005829 238.0
PYH3_k127_6896187_6 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000348 236.0
PYH3_k127_6896187_7 pyrroloquinoline quinone binding K01176 - 3.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000006043 245.0
PYH3_k127_6896187_8 Protein of unknown function, DUF393 - - - 0.00000000000000000000000000000000000000006649 157.0
PYH3_k127_6896187_9 Predicted membrane protein (DUF2177) - - - 0.000000000000000002751 96.0
PYH3_k127_6911765_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 313.0
PYH3_k127_6911765_1 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 304.0
PYH3_k127_6911765_2 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007705 276.0
PYH3_k127_6911765_3 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000002386 222.0
PYH3_k127_6911765_4 Acid phosphatase homologues - - - 0.000000000003263 75.0
PYH3_k127_6911765_5 Sporulation related domain K03749 - - 0.0001171 52.0
PYH3_k127_6922759_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 319.0
PYH3_k127_6922759_1 Outer membrane efflux protein K12340 - - 0.00000000000000000000000000000000000000000000000000000000000000004145 244.0
PYH3_k127_6922759_2 Yip1 domain - - - 0.000000000005321 76.0
PYH3_k127_6949186_0 Mur ligase family, catalytic domain K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 378.0
PYH3_k127_6949186_1 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001774 262.0
PYH3_k127_6949186_2 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000148 73.0
PYH3_k127_6949186_3 Protein of unknown function (DUF1573) - - - 0.0000000000001767 83.0
PYH3_k127_6950968_0 cellulose binding - - - 0.0 1256.0
PYH3_k127_6950968_1 D-xylulose 5-phosphate/D-fructose 6-phosphate phosphoketolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003813 524.0
PYH3_k127_6950968_10 nitric oxide dioxygenase activity - - - 0.000000000000000000001174 100.0
PYH3_k127_6950968_11 Domain of unknown function (DUF4136) - - - 0.00001009 55.0
PYH3_k127_6950968_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 510.0
PYH3_k127_6950968_3 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 441.0
PYH3_k127_6950968_4 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 - 5.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003843 440.0
PYH3_k127_6950968_5 Belongs to the enoyl-CoA hydratase isomerase family K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 428.0
PYH3_k127_6950968_6 PFAM Phosphomethylpyrimidine kinase type-1 K00941 GO:0008150,GO:0040007 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000003175 177.0
PYH3_k127_6950968_7 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000004603 175.0
PYH3_k127_6950968_8 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.00000000000000000000000000000000000000007099 156.0
PYH3_k127_6950968_9 Redoxin K03564 - 1.11.1.15 0.0000000000000000000000000000000000001968 152.0
PYH3_k127_6952538_0 WD40-like Beta Propeller Repeat - - - 0.000000000000000000000000000000000000000000000000000000000000006674 243.0
PYH3_k127_6952538_1 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.000000000000003226 75.0
PYH3_k127_6990405_0 arylsulfatase A K01130 - 3.1.6.1 4.647e-264 822.0
PYH3_k127_6990405_1 deca-heme c-type cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 486.0
PYH3_k127_6990405_2 AsmA-like C-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 434.0
PYH3_k127_6990405_3 NMT1-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 322.0
PYH3_k127_6990405_4 Protein involved in meta-pathway of phenol degradation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001147 304.0
PYH3_k127_6990405_5 Sortase family K07284 - 3.4.22.70 0.000000000000000000000000000000000000000000000002688 182.0
PYH3_k127_6990405_6 - - - - 0.000000000000000000000000000000000000000113 156.0
PYH3_k127_7032332_0 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000001426 243.0
PYH3_k127_7032332_1 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000001629 192.0
PYH3_k127_7032332_2 ABC transporter, permease protein K02004 - - 0.0000000000000000000000000000000000000000000001692 184.0
PYH3_k127_7032332_3 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000008823 156.0
PYH3_k127_7032332_4 outer membrane efflux protein - - - 0.0000000000000000000000004492 121.0
PYH3_k127_7051811_0 Malate synthase K01638 - 2.3.3.9 0.0 1169.0
PYH3_k127_7051811_1 NMT1-like family K02051 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 419.0
PYH3_k127_7051811_10 carboxylic ester hydrolase activity - - - 0.0000000000000005452 87.0
PYH3_k127_7051811_11 ankyrin repeats K18477 - 2.1.1.322 0.00002313 57.0
PYH3_k127_7051811_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 401.0
PYH3_k127_7051811_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009072 380.0
PYH3_k127_7051811_4 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 303.0
PYH3_k127_7051811_5 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002394 259.0
PYH3_k127_7051811_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000004919 208.0
PYH3_k127_7051811_7 Peptidase family M23 K21471 - - 0.0000000000000000000000000000000004547 147.0
PYH3_k127_7051811_8 stage II sporulation protein E K07315 - 3.1.3.3 0.00000000000000000000000000001188 132.0
PYH3_k127_7051811_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000005533 124.0
PYH3_k127_7067017_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 526.0
PYH3_k127_7067017_1 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000001442 127.0
PYH3_k127_7067017_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000008188 78.0
PYH3_k127_7089912_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1072.0
PYH3_k127_7089912_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.702e-252 807.0
PYH3_k127_7089912_10 - - - - 0.000000000000000000000000003081 129.0
PYH3_k127_7089912_11 extracellular polysaccharide biosynthetic process K00568,K03561,K07011,K20444 - 2.1.1.222,2.1.1.64 0.00000000000000000001943 106.0
PYH3_k127_7089912_12 Prokaryotic Cytochrome C oxidase subunit IV K02277 - 1.9.3.1 0.0000035 58.0
PYH3_k127_7089912_13 - - - - 0.0001844 51.0
PYH3_k127_7089912_2 Polysulphide reductase, NrfD K00185 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 599.0
PYH3_k127_7089912_3 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 359.0
PYH3_k127_7089912_4 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000487 340.0
PYH3_k127_7089912_5 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001021 287.0
PYH3_k127_7089912_6 PFAM cytochrome c oxidase, subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000002256 235.0
PYH3_k127_7089912_7 Protein of unknown function (DUF3341) - - - 0.00000000000000000000000000000000000000000000000000000009796 212.0
PYH3_k127_7089912_8 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000001396 196.0
PYH3_k127_7089912_9 PFAM Stage II sporulation - - - 0.00000000000000000000000000000000000002822 159.0
PYH3_k127_7175256_0 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001576 234.0
PYH3_k127_7175256_1 methylamine metabolic process - - - 0.0000000000000000000000000000000000001642 147.0
PYH3_k127_7175256_2 protein involved in formation of curli polymers - - - 0.000000000000000000000000000003697 131.0
PYH3_k127_7175256_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K01760 - 4.4.1.8 0.0000000000000000000000000143 111.0
PYH3_k127_7175256_4 COG2202 FOG PAS PAC domain - - - 0.000000001154 72.0
PYH3_k127_7175256_5 histidine kinase A domain protein - - - 0.0006568 53.0
PYH3_k127_7181880_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 483.0
PYH3_k127_7181880_1 PFAM glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 428.0
PYH3_k127_7181880_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006857 282.0
PYH3_k127_7181880_3 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000237 150.0
PYH3_k127_7181880_4 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000002297 88.0
PYH3_k127_7221307_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 4.933e-301 939.0
PYH3_k127_7221307_1 Elongation factor Tu C-terminal domain K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 8.431e-196 616.0
PYH3_k127_7221307_10 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000002199 151.0
PYH3_k127_7221307_11 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000003835 92.0
PYH3_k127_7221307_12 Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively K01243 - 3.2.2.9 0.00007471 53.0
PYH3_k127_7221307_2 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 610.0
PYH3_k127_7221307_3 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 384.0
PYH3_k127_7221307_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000001111 241.0
PYH3_k127_7221307_5 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005988 243.0
PYH3_k127_7221307_6 Squalene/phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000001768 245.0
PYH3_k127_7221307_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.000000000000000000000000000000000000000000000000000000000000003341 220.0
PYH3_k127_7221307_8 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000008101 161.0
PYH3_k127_7221307_9 Forms part of the polypeptide exit tunnel K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000001015 162.0
PYH3_k127_7241284_0 histone H2A K63-linked ubiquitination K10914 - - 0.000000000000000000000000000001056 130.0
PYH3_k127_7241284_1 UPF0761 membrane protein K07058 - - 0.000000000000001976 90.0
PYH3_k127_7241284_2 ABC-type multidrug transport system ATPase component - - - 0.000000000001788 79.0
PYH3_k127_7241284_3 - - - - 0.0000263 52.0
PYH3_k127_7256930_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 399.0
PYH3_k127_7256930_1 Dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002964 276.0
PYH3_k127_7256930_11 - - - - 0.0006466 48.0
PYH3_k127_7256930_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000000000000000000000004284 213.0
PYH3_k127_7256930_3 DinB superfamily - - - 0.000000000000000000000000000000000000000000000000000000001173 221.0
PYH3_k127_7256930_4 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000007586 199.0
PYH3_k127_7256930_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000002663 184.0
PYH3_k127_7256930_6 helix_turn_helix, mercury resistance K22491 - - 0.000000000000000000000000005602 121.0
PYH3_k127_7256930_7 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000002622 102.0
PYH3_k127_7256930_8 Putative esterase K07214 - - 0.000000000000000001124 98.0
PYH3_k127_7256930_9 pseudouridylate synthase K06175 - 5.4.99.26 0.0000000003404 70.0
PYH3_k127_7278597_0 PFAM Acetyl-CoA dehydrogenase-like C-terminal domain, Acyl-CoA dehydrogenase domain-containing protein, acyl-CoA dehydrogenase domain-containing protein K09456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 492.0
PYH3_k127_7278597_1 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 389.0
PYH3_k127_7278597_2 Iron-storage protein K02217 - 1.16.3.2 0.00000000000000000000000000000000000000000000000000000000008463 208.0
PYH3_k127_7278597_3 hemerythrin HHE cation binding domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000003289 154.0
PYH3_k127_7278597_4 DinB family - - - 0.000000000000000000000000000000000000006841 153.0
PYH3_k127_7278597_5 acyl-coa-binding protein - - - 0.00000000000000000000000000003246 119.0
PYH3_k127_7292773_0 WD40-like Beta Propeller Repeat K03641,K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 449.0
PYH3_k127_7292773_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016829,GO:0016840,GO:0016843,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0040007,GO:0042364,GO:0042802,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 411.0
PYH3_k127_7292773_2 tRNA 3'-trailer cleavage K00784,K01120 - 3.1.26.11,3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000003652 231.0
PYH3_k127_7292773_3 PFAM Aminotransferase class I and II K05825 - - 0.0000000000000000000000000000000000000000000000000000000000002668 226.0
PYH3_k127_7292773_4 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000004247 185.0
PYH3_k127_7292773_6 DNA processing protein DprA K04096 - - 0.00002156 51.0
PYH3_k127_7296225_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000004149 217.0
PYH3_k127_7296225_1 deoxyhypusine monooxygenase activity K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000001244 190.0
PYH3_k127_7296225_2 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.0000000000000000000000000000000000000000000000000732 189.0
PYH3_k127_7296225_3 Psort location Cytoplasmic, score 8.96 - - - 0.000000000000000000000000000000000000001312 151.0
PYH3_k127_7296225_4 Part of the ABC transporter complex ZnuABC involved in zinc import. Responsible for energy coupling to the transport system K09817 - - 0.000000000000000000000000000008797 130.0
PYH3_k127_7296225_5 ABC-type Mn2 Zn2 transport systems permease components K09816 - - 0.0000000000001737 82.0
PYH3_k127_7296225_6 Homoserine O-succinyltransferase - - - 0.0000002623 62.0
PYH3_k127_7302146_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 554.0
PYH3_k127_7302146_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000001705 249.0
PYH3_k127_7302146_2 malonyl CoA-acyl carrier protein transacylase K00645,K15355 - 2.3.1.39 0.00000000000000000000000000000000000006548 147.0
PYH3_k127_7302146_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000009169 113.0
PYH3_k127_7316442_0 Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 479.0
PYH3_k127_7316442_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 423.0
PYH3_k127_7316442_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000392 66.0
PYH3_k127_7316442_3 PFAM Tetrapyrrole (Corrin Porphyrin) Methylases K13542 - 2.1.1.107,4.2.1.75 0.0002498 53.0
PYH3_k127_7343725_0 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 404.0
PYH3_k127_7343725_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 356.0
PYH3_k127_7343725_10 PFAM pentapeptide repeat protein - - - 0.000000000000000000000000005932 128.0
PYH3_k127_7343725_11 EamA-like transporter family - - - 0.0000000000000000000002165 108.0
PYH3_k127_7343725_12 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000004664 72.0
PYH3_k127_7343725_13 Domain of unknown function (DUF4340) - - - 0.0005321 52.0
PYH3_k127_7343725_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004511 301.0
PYH3_k127_7343725_3 e3 binding domain K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 289.0
PYH3_k127_7343725_4 N-Acetylmuramoyl-L-alanine amidase K01448,K02172 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000003192 275.0
PYH3_k127_7343725_5 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000005864 233.0
PYH3_k127_7343725_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000000000000000000001356 198.0
PYH3_k127_7343725_7 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000005278 156.0
PYH3_k127_7343725_8 Hydrolase - - - 0.0000000000000000000000000000000001369 145.0
PYH3_k127_7343725_9 4Fe-4S single cluster domain of Ferredoxin I - - - 0.000000000000000000000000005049 115.0
PYH3_k127_7346940_0 Sortilin, neurotensin receptor 3, - - - 0.0 1281.0
PYH3_k127_7346940_1 Peptidase dimerisation domain - - - 1.18e-197 634.0
PYH3_k127_7346940_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006944 520.0
PYH3_k127_7346940_3 ASPIC and UnbV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005786 311.0
PYH3_k127_7346940_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000003309 268.0
PYH3_k127_7346940_5 Forkhead associated domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000297 247.0
PYH3_k127_7346940_6 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.0000000000000000000000000000000000000000000007876 192.0
PYH3_k127_7346940_7 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000000772 98.0
PYH3_k127_7346940_8 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.00000000008953 62.0
PYH3_k127_7348432_0 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000007966 231.0
PYH3_k127_7348432_1 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000003223 179.0
PYH3_k127_7348432_2 HD domain - - - 0.00000000000000000000000000000000000000000005693 181.0
PYH3_k127_7348432_3 histidine kinase HAMP region domain protein K13598 - 2.7.13.3 0.000000464 61.0
PYH3_k127_7360859_0 peptidyl-tyrosine sulfation - - - 5.998e-219 700.0
PYH3_k127_7360859_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004656 520.0
PYH3_k127_7360859_2 peptidyl-tyrosine sulfation - - - 0.000000496 55.0
PYH3_k127_7386833_0 filamentation induced by cAMP protein Fic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006509 512.0
PYH3_k127_7386833_1 3-beta hydroxysteroid dehydrogenase/isomerase family K10011,K12449 - 1.1.1.305,2.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006821 466.0
PYH3_k127_7386833_2 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009281 305.0
PYH3_k127_7386833_3 PFAM thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003639 243.0
PYH3_k127_7386833_4 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000004586 237.0
PYH3_k127_7386833_5 cellulose binding - - - 0.000000000000000001597 99.0
PYH3_k127_74023_0 Belongs to the heat shock protein 70 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 580.0
PYH3_k127_74023_1 DNA polymerase III subunit epsilon K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000003631 237.0
PYH3_k127_74023_2 Stage II sporulation protein E K07315 - 3.1.3.3 0.0000000000000000000000000000001448 139.0
PYH3_k127_74023_3 PQ loop repeat K15383 - - 0.00000002683 67.0
PYH3_k127_7473459_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.228e-238 747.0
PYH3_k127_7473459_1 - K07039 - - 0.0000000000000000000000000000000000000000000001402 183.0
PYH3_k127_7473459_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000353 135.0
PYH3_k127_7473459_3 - K07039 - - 0.000000000007303 68.0
PYH3_k127_7473459_4 Bacterial antitoxin of type II TA system, VapB - - - 0.0001312 47.0
PYH3_k127_7473459_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0002803 51.0
PYH3_k127_7512769_0 Two component regulator propeller K07315,K12132,K13924 - 2.1.1.80,2.7.11.1,3.1.1.61,3.1.3.3 1.387e-247 802.0
PYH3_k127_7512769_1 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 555.0
PYH3_k127_7512769_10 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.0000000000000000000000000000000000002919 153.0
PYH3_k127_7512769_11 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000001109 143.0
PYH3_k127_7512769_12 SMART protein phosphatase 2C domain protein - - - 0.0000000000000000000000000000001118 145.0
PYH3_k127_7512769_13 - - - - 0.0009052 47.0
PYH3_k127_7512769_2 PFAM Aminotransferase class I and II K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000396 524.0
PYH3_k127_7512769_3 Protein of unknown function (DUF3641) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004768 497.0
PYH3_k127_7512769_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 358.0
PYH3_k127_7512769_5 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 320.0
PYH3_k127_7512769_6 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 301.0
PYH3_k127_7512769_7 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.0000000000000000000000000000000000000000000000000000003038 198.0
PYH3_k127_7512769_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000004122 181.0
PYH3_k127_7512769_9 - - - - 0.0000000000000000000000000000000000000002232 160.0
PYH3_k127_7544086_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 490.0
PYH3_k127_7544086_1 Histidine kinase K10681 - 2.7.13.3 0.00000000000000000006462 105.0
PYH3_k127_7544086_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00004131 49.0
PYH3_k127_7563171_0 Bacterial regulatory protein, Fis family K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 368.0
PYH3_k127_7563171_1 Selenocysteine synthase N terminal K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000159 274.0
PYH3_k127_764387_0 GMC oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000001045 211.0
PYH3_k127_764387_1 D-arabinono-1,4-lactone oxidase - - - 0.0000000000000000000000000004619 132.0
PYH3_k127_764387_2 - - - - 0.000000000000000000005897 106.0
PYH3_k127_764387_3 Lecithin:cholesterol acyltransferase - - - 0.0000000000001392 83.0
PYH3_k127_7649472_0 TIGRFAM type VI secretion protein, VC_A0110 family K11896 - - 2.282e-199 638.0
PYH3_k127_7649472_1 TIGRFAM type VI secretion protein, VC_A0111 family K11895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001533 306.0
PYH3_k127_7649472_2 Type VI secretion protein, EvpB/VC_A0108, tail sheath K11900 - - 0.000000000000000000000000000000000000000000000000000000000000000000005031 236.0
PYH3_k127_7649472_3 C-terminal, D2-small domain, of ClpB protein K11907 - - 0.0000000000000000000000000000000000000000000000000000007817 197.0
PYH3_k127_7649472_4 Gene 25-like lysozyme K11897 - - 0.0000000000000000000000000000000001959 138.0
PYH3_k127_7703356_0 PFAM response regulator receiver K07713 - - 9.194e-200 633.0
PYH3_k127_7703356_1 HAMP domain K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 487.0
PYH3_k127_7703356_2 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000612 359.0
PYH3_k127_7703356_3 Peptidase family M54 K06974 - - 0.000000000000000000000000000000000000000000001771 170.0
PYH3_k127_7703356_4 ATP-dependent DNA helicase activity K01144,K07464,K16898 - 3.1.11.5,3.1.12.1,3.6.4.12 0.000000001073 65.0
PYH3_k127_7708730_0 PFAM DAHP synthetase I KDSA K03856,K04518,K14170 GO:0003674,GO:0003824,GO:0004106,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006570,GO:0006571,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016866,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 2.5.1.54,4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 463.0
PYH3_k127_7708730_1 synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005158 275.0
PYH3_k127_7708730_2 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000007427 160.0
PYH3_k127_7708730_3 PIN domain - - - 0.0000000000000000000000004738 110.0
PYH3_k127_7708730_4 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000046 113.0
PYH3_k127_7708730_5 - - - - 0.00000000000000005824 83.0
PYH3_k127_7708730_6 - - - - 0.000000000008288 76.0
PYH3_k127_7708730_7 GDSL-like Lipase/Acylhydrolase family - - - 0.00000002494 65.0
PYH3_k127_7708730_8 Homocysteine S-methyltransferase K00547,K21169 - 2.1.1.10 0.0007204 44.0
PYH3_k127_7746312_0 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 432.0
PYH3_k127_7746312_1 Selenocysteine-specific translation elongation factor K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004049 391.0
PYH3_k127_7746312_10 Type II transport protein GspH K08084 - - 0.0007529 49.0
PYH3_k127_7746312_2 UbiA prenyltransferase family K03179 - 2.5.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000001053 279.0
PYH3_k127_7746312_3 Deoxynucleoside kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000005058 231.0
PYH3_k127_7746312_4 Flavoprotein K03186 - 2.5.1.129 0.00000000000000000000000000000000001874 144.0
PYH3_k127_7746312_5 Probable zinc-ribbon domain - - - 0.000000000000000000000000000000004241 131.0
PYH3_k127_7746312_6 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000002313 126.0
PYH3_k127_7746312_7 CYTH K05873 - 4.6.1.1 0.00000000000000000003074 103.0
PYH3_k127_7746312_8 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000000000005875 91.0
PYH3_k127_7746312_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.0002174 54.0
PYH3_k127_7771353_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 8.279e-201 633.0
PYH3_k127_7771353_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 589.0
PYH3_k127_7771353_10 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000003425 211.0
PYH3_k127_7771353_11 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000002852 209.0
PYH3_k127_7771353_12 Protein of unknown function (DUF2400) - - - 0.0000000000000000000000000000000000000000000000001465 189.0
PYH3_k127_7771353_13 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000855 187.0
PYH3_k127_7771353_14 Outer membrane protein protective antigen OMA87 - - - 0.0000000000000000000000000000000000000008474 169.0
PYH3_k127_7771353_15 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000001664 142.0
PYH3_k127_7771353_16 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000001058 124.0
PYH3_k127_7771353_17 PFAM Redoxin - - - 0.00000000000000000000002339 115.0
PYH3_k127_7771353_18 TPM domain - - - 0.000000000000000002344 91.0
PYH3_k127_7771353_19 PFAM Phosphoglycerate mutase K08296 - - 0.000000000000008271 80.0
PYH3_k127_7771353_2 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008892 599.0
PYH3_k127_7771353_20 UbiA prenyltransferase family K17105 - 2.5.1.42 0.0000000000002317 82.0
PYH3_k127_7771353_21 Integral membrane protein DUF92 - - - 0.00000000008335 66.0
PYH3_k127_7771353_3 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 396.0
PYH3_k127_7771353_4 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 364.0
PYH3_k127_7771353_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K01810,K13810 - 2.2.1.2,5.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 343.0
PYH3_k127_7771353_6 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005259 300.0
PYH3_k127_7771353_7 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0043167,GO:0043169,GO:0046872,GO:0046914 - 0.0000000000000000000000000000000000000000000000000000000000000000000006225 240.0
PYH3_k127_7771353_8 Histidinol phosphate phosphatase, HisJ family K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000002168 224.0
PYH3_k127_7771353_9 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000000000000000000000000000000000000000000000000000000000002647 219.0
PYH3_k127_7775544_0 glucose phosphotransferase - - - 0.0000000000000000000000000000000000000000000000000004335 202.0
PYH3_k127_7779592_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.215e-202 646.0
PYH3_k127_7779592_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001791 589.0
PYH3_k127_7779592_2 Transmembrane secretion effector K08225 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005451 304.0
PYH3_k127_7779592_3 Tyrosine 3-monooxygenase K00501 GO:0000003,GO:0001101,GO:0001654,GO:0001666,GO:0001678,GO:0001754,GO:0001963,GO:0001975,GO:0002237,GO:0003007,GO:0003008,GO:0003674,GO:0003824,GO:0004497,GO:0004511,GO:0005488,GO:0005506,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005783,GO:0005790,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006570,GO:0006584,GO:0006585,GO:0006629,GO:0006631,GO:0006643,GO:0006665,GO:0006720,GO:0006725,GO:0006807,GO:0006810,GO:0006836,GO:0006950,GO:0006970,GO:0007154,GO:0007267,GO:0007268,GO:0007275,GO:0007399,GO:0007417,GO:0007420,GO:0007423,GO:0007444,GO:0007507,GO:0007564,GO:0007568,GO:0007591,GO:0007593,GO:0007600,GO:0007601,GO:0007605,GO:0007610,GO:0007611,GO:0007612,GO:0007613,GO:0007617,GO:0007618,GO:0007619,GO:0007622,GO:0007623,GO:0007626,GO:0007631,GO:0007638,GO:0008016,GO:0008021,GO:0008049,GO:0008144,GO:0008150,GO:0008152,GO:0008198,GO:0008199,GO:0008344,GO:0009058,GO:0009072,GO:0009266,GO:0009314,GO:0009404,GO:0009410,GO:0009414,GO:0009415,GO:0009416,GO:0009605,GO:0009607,GO:0009611,GO:0009612,GO:0009617,GO:0009628,GO:0009635,GO:0009636,GO:0009651,GO:0009653,GO:0009712,GO:0009713,GO:0009719,GO:0009725,GO:0009743,GO:0009746,GO:0009749,GO:0009790,GO:0009820,GO:0009887,GO:0009888,GO:0009898,GO:0009987,GO:0009991,GO:0010033,GO:0010035,GO:0010038,GO:0010042,GO:0010043,GO:0010243,GO:0010259,GO:0010632,GO:0012505,GO:0012506,GO:0014070,GO:0014075,GO:0014823,GO:0015837,GO:0015842,GO:0016020,GO:0016043,GO:0016137,GO:0016491,GO:0016597,GO:0016705,GO:0016714,GO:0017085,GO:0017144,GO:0018958,GO:0018963,GO:0019098,GO:0019438,GO:0019725,GO:0019748,GO:0019752,GO:0019825,GO:0019899,GO:0019904,GO:0019953,GO:0021537,GO:0021543,GO:0021700,GO:0021987,GO:0022008,GO:0022404,GO:0022414,GO:0022607,GO:0023052,GO:0030133,GO:0030154,GO:0030182,GO:0030334,GO:0030424,GO:0030425,GO:0030534,GO:0030659,GO:0030900,GO:0031076,GO:0031090,GO:0031406,GO:0031410,GO:0031667,GO:0031960,GO:0031982,GO:0032094,GO:0032355,GO:0032496,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032879,GO:0033076,GO:0033162,GO:0033267,GO:0033500,GO:0033993,GO:0034284,GO:0034607,GO:0034617,GO:0034641,GO:0035094,GO:0035176,GO:0035178,GO:0035220,GO:0035240,GO:0035295,GO:0035690,GO:0035900,GO:0035902,GO:0036094,GO:0036293,GO:0036477,GO:0040011,GO:0040012,GO:0040040,GO:0042214,GO:0042221,GO:0042303,GO:0042330,GO:0042335,GO:0042414,GO:0042415,GO:0042416,GO:0042417,GO:0042418,GO:0042421,GO:0042423,GO:0042461,GO:0042462,GO:0042470,GO:0042493,GO:0042537,GO:0042592,GO:0042593,GO:0042745,GO:0042755,GO:0042995,GO:0043005,GO:0043010,GO:0043025,GO:0043052,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043195,GO:0043204,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043279,GO:0043434,GO:0043436,GO:0043473,GO:0043648,GO:0043679,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044297,GO:0044306,GO:0044422,GO:0044424,GO:0044425,GO:0044433,GO:0044444,GO:0044446,GO:0044456,GO:0044459,GO:0044463,GO:0044464,GO:0044703,GO:0045009,GO:0045202,GO:0045471,GO:0045472,GO:0046189,GO:0046483,GO:0046530,GO:0046677,GO:0046684,GO:0046872,GO:0046914,GO:0046958,GO:0046959,GO:0048037,GO:0048048,GO:0048066,GO:0048067,GO:0048070,GO:0048079,GO:0048082,GO:0048085,GO:0048468,GO:0048511,GO:0048512,GO:0048513,GO:0048545,GO:0048562,GO:0048568,GO:0048592,GO:0048593,GO:0048596,GO:0048598,GO:0048609,GO:0048666,GO:0048699,GO:0048731,GO:0048770,GO:0048856,GO:0048869,GO:0048878,GO:0050662,GO:0050789,GO:0050793,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0050953,GO:0050954,GO:0051179,GO:0051234,GO:0051239,GO:0051259,GO:0051260,GO:0051262,GO:0051270,GO:0051289,GO:0051384,GO:0051385,GO:0051412,GO:0051602,GO:0051641,GO:0051649,GO:0051703,GO:0051704,GO:0051705,GO:0051707,GO:0051716,GO:0052314,GO:0055082,GO:0055114,GO:0060179,GO:0060322,GO:0060429,GO:0065003,GO:0065007,GO:0065008,GO:0070382,GO:0070405,GO:0070482,GO:0070848,GO:0070887,GO:0071241,GO:0071248,GO:0071287,GO:0071310,GO:0071312,GO:0071316,GO:0071322,GO:0071326,GO:0071331,GO:0071333,GO:0071363,GO:0071417,GO:0071495,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0071944,GO:0072359,GO:0090596,GO:0090741,GO:0097159,GO:0097164,GO:0097237,GO:0097305,GO:0097366,GO:0097447,GO:0097458,GO:0097708,GO:0098552,GO:0098562,GO:0098588,GO:0098700,GO:0098793,GO:0098805,GO:0098916,GO:0099503,GO:0099504,GO:0099536,GO:0099537,GO:0120025,GO:0120038,GO:0150034,GO:1901135,GO:1901338,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901615,GO:1901617,GO:1901652,GO:1901654,GO:1901657,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1903522,GO:2000026,GO:2000145,GO:2000274 1.14.16.2 0.00000000000000000000000000000000000000000000000000000000000003144 226.0
PYH3_k127_7779592_4 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000003611 198.0
PYH3_k127_7779592_5 - - - - 0.000000000000000000000000000000000000002981 161.0
PYH3_k127_7779592_6 AraC-like ligand binding domain - - - 0.00000000000000000000000000000001531 134.0
PYH3_k127_7779592_7 COG2335 Secreted and surface protein containing fasciclin-like repeats K19519 - - 0.00000000000000000000000001442 111.0
PYH3_k127_7802778_0 Belongs to the peptidase S8 family K13275 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 492.0
PYH3_k127_7802778_1 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 458.0
PYH3_k127_7802778_10 AAA domain, putative AbiEii toxin, Type IV TA system - - - 0.00000000000000000000000000000000000000000000000000000000000001564 239.0
PYH3_k127_7802778_11 B12 binding domain K14084 - - 0.0000000000000000000000000000000000000000000000000002118 192.0
PYH3_k127_7802778_12 B12 binding domain K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000002748 201.0
PYH3_k127_7802778_13 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000009647 166.0
PYH3_k127_7802778_14 HlyD membrane-fusion protein of T1SS K01993 - - 0.00000000000000000000000000000000000000000003818 176.0
PYH3_k127_7802778_15 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000001223 174.0
PYH3_k127_7802778_16 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000001259 162.0
PYH3_k127_7802778_17 macromolecule localization K01992,K09690 - - 0.000000000000000000000000000000000000000009054 174.0
PYH3_k127_7802778_18 Transcriptional regulator, Crp Fnr family K01420,K10914 - - 0.0000000000000000000000000000000000000000702 160.0
PYH3_k127_7802778_19 Methyltransferase domain K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000216 145.0
PYH3_k127_7802778_2 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009478 372.0
PYH3_k127_7802778_20 Vitamin B12 dependent methionine synthase activation - - - 0.000000000007862 78.0
PYH3_k127_7802778_21 Peptidoglycan-binding domain 1 protein - - - 0.00000000001063 74.0
PYH3_k127_7802778_22 outer membrane efflux protein - - - 0.00001745 50.0
PYH3_k127_7802778_3 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 310.0
PYH3_k127_7802778_4 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 309.0
PYH3_k127_7802778_5 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000256 276.0
PYH3_k127_7802778_6 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001001 293.0
PYH3_k127_7802778_7 ADP-heptose-lipopolysaccharide heptosyltransferase activity K02843 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004889 270.0
PYH3_k127_7802778_8 pfam abc K09691 - - 0.0000000000000000000000000000000000000000000000000000000000000000003453 236.0
PYH3_k127_7802778_9 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000001086 241.0
PYH3_k127_7832577_0 Peptidase m28 - - - 1.577e-212 676.0
PYH3_k127_7832577_1 NapC/NirT cytochrome c family, N-terminal region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003428 602.0
PYH3_k127_7832577_10 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 358.0
PYH3_k127_7832577_11 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 319.0
PYH3_k127_7832577_12 ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003089 314.0
PYH3_k127_7832577_13 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 321.0
PYH3_k127_7832577_14 PFAM Major facilitator superfamily K08224 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 317.0
PYH3_k127_7832577_15 PFAM peptidase U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 323.0
PYH3_k127_7832577_16 peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000117 299.0
PYH3_k127_7832577_17 CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001468 287.0
PYH3_k127_7832577_18 PFAM Extracellular ligand-binding receptor K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007169 286.0
PYH3_k127_7832577_19 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003261 296.0
PYH3_k127_7832577_2 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 512.0
PYH3_k127_7832577_20 iron ion homeostasis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003572 288.0
PYH3_k127_7832577_21 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000009281 263.0
PYH3_k127_7832577_22 Abc transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001515 265.0
PYH3_k127_7832577_23 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007454 273.0
PYH3_k127_7832577_24 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005867 253.0
PYH3_k127_7832577_25 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000002658 235.0
PYH3_k127_7832577_26 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000001215 226.0
PYH3_k127_7832577_27 transport system permease K01998 - - 0.0000000000000000000000000000000000000000000000000000000000237 229.0
PYH3_k127_7832577_28 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.0000000000000000000000000000000000000000000000000000000003871 218.0
PYH3_k127_7832577_29 PFAM CBS domain K04767 - - 0.00000000000000000000000000000000000000000000000000005804 198.0
PYH3_k127_7832577_3 Protein of unknown function (DUF2891) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008703 484.0
PYH3_k127_7832577_30 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000005728 192.0
PYH3_k127_7832577_31 PFAM OsmC family protein K04063 - - 0.00000000000000000000000000000000000000000007788 175.0
PYH3_k127_7832577_32 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.000000000000000000000000000000002854 137.0
PYH3_k127_7832577_33 Peptidase family U32 K08303 - - 0.00000000000000000000000000000002697 136.0
PYH3_k127_7832577_34 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000001812 136.0
PYH3_k127_7832577_35 Phosphate-selective porin O and P - - - 0.0000000000000000000000000001559 130.0
PYH3_k127_7832577_36 diguanylate cyclase - - - 0.000000000000000000000000001791 122.0
PYH3_k127_7832577_37 Pas domain - - - 0.0000000000000000000001708 107.0
PYH3_k127_7832577_38 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016491,GO:0016620,GO:0016903,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042866,GO:0043436,GO:0043891,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0055114,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576 1.2.1.12 0.0000000000000009201 78.0
PYH3_k127_7832577_39 Helix-turn-helix XRE-family like proteins K21498 - - 0.000000000000002806 89.0
PYH3_k127_7832577_4 Diguanylate cyclase phosphodiesterase with PAS PAC sensor(S) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 501.0
PYH3_k127_7832577_40 Domain of unknown function (DUF4388) - - - 0.00001383 59.0
PYH3_k127_7832577_5 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 492.0
PYH3_k127_7832577_6 including yeast histone deacetylase and acetoin utilization protein K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 458.0
PYH3_k127_7832577_7 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 454.0
PYH3_k127_7832577_8 AMP-binding enzyme C-terminal domain K18660,K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006134 427.0
PYH3_k127_7832577_9 PFAM Extracellular ligand-binding receptor K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 398.0
PYH3_k127_7869782_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005762 400.0
PYH3_k127_7869782_1 Response regulator receiver domain - - - 0.00000000000000000000000005855 119.0
PYH3_k127_7873606_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009507,GO:0009536,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000242 585.0
PYH3_k127_7873606_1 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 386.0
PYH3_k127_7873606_2 Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate K00598 - 2.1.1.144 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004325 280.0
PYH3_k127_7873606_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000004466 236.0
PYH3_k127_7873606_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000001139 194.0
PYH3_k127_7873606_6 Belongs to the UPF0235 family K09131 - - 0.0003763 53.0
PYH3_k127_7889266_0 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.00000000000000000000000000000000000000000003448 184.0
PYH3_k127_7889266_1 Phosphoserine phosphatase - - - 0.00000001169 69.0
PYH3_k127_7903560_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 424.0
PYH3_k127_7903560_1 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K07713,K07714,K19641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 409.0
PYH3_k127_7903560_2 Inner membrane component of T3SS, cytoplasmic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 332.0
PYH3_k127_7903560_3 carboxylic acid catabolic process - - - 0.0000000000000000000000000000000000000000004639 169.0
PYH3_k127_7903560_4 Binds the 23S rRNA K02909 - - 0.000000000000000000004512 109.0
PYH3_k127_7903560_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000003046 90.0
PYH3_k127_7903560_6 - - - - 0.000000000001793 75.0
PYH3_k127_7903560_7 peptidase K01295 - 3.4.17.11 0.0000000108 56.0
PYH3_k127_7968826_0 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 397.0
PYH3_k127_7968826_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000003218 228.0
PYH3_k127_7968826_2 MotA TolQ ExbB proton channel K03561,K03562 - - 0.000000000000000000000000000000000000000000000000000000000001607 217.0
PYH3_k127_7968826_3 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000003173 203.0
PYH3_k127_7968826_4 TIGRFAM riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000001279 189.0
PYH3_k127_7968826_5 Biopolymer transport protein ExbD/TolR - - - 0.00000000000000000000001561 106.0
PYH3_k127_7968826_6 Tetratricopeptide repeat - - - 0.00000000000000000000008506 111.0
PYH3_k127_7968826_7 Biopolymer transport protein K03559,K03560 - - 0.0000000000000000000002181 101.0
PYH3_k127_7968826_8 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000003509 87.0
PYH3_k127_8009543_0 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 380.0
PYH3_k127_8009543_1 gluconolactonase K01053 - 3.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 363.0
PYH3_k127_8009543_2 Protein of unknown function (DUF692) K09930 - - 0.000000000000000000000000000000000000001259 153.0
PYH3_k127_8009543_3 Putative DNA-binding domain - - - 0.000000000000000000000000000000005145 141.0
PYH3_k127_8009543_4 SMP-30 Gluconolaconase LRE domain protein K01053 - 3.1.1.17 0.000009793 48.0
PYH3_k127_8009543_5 - - - - 0.0005125 48.0
PYH3_k127_8038455_0 PFAM amino acid permease-associated region K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 417.0
PYH3_k127_8038455_1 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 360.0
PYH3_k127_8038455_10 - K07039 - - 0.00000005061 55.0
PYH3_k127_8038455_11 PFAM glycosyl transferase family 2 - - - 0.00000006814 63.0
PYH3_k127_8038455_12 - - - - 0.0000002893 63.0
PYH3_k127_8038455_13 Male sterility protein K01784,K19997 - 5.1.3.2,5.1.3.26 0.0000524 56.0
PYH3_k127_8038455_14 Dolichyl-phosphate-mannose-protein mannosyltransferase K14340 - - 0.0001228 55.0
PYH3_k127_8038455_2 Glycosyl transferase, family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000005809 210.0
PYH3_k127_8038455_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000163 191.0
PYH3_k127_8038455_4 hydrolase, HAD-superfamily, subfamily IIIA K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000003588 184.0
PYH3_k127_8038455_5 NmrA-like family - - - 0.00000000000000000000003469 115.0
PYH3_k127_8038455_6 peptidyl-tyrosine sulfation - - - 0.000000000000001166 87.0
PYH3_k127_8038455_7 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000001123 68.0
PYH3_k127_8038455_8 Methyltransferase domain - - - 0.0000000114 68.0
PYH3_k127_8038455_9 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000001336 68.0
PYH3_k127_8049268_0 Involved in the tonB-independent uptake of proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 556.0
PYH3_k127_8049268_1 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 518.0
PYH3_k127_8049268_10 Cytidylate kinase-like family - - - 0.0000000000000000000000000000000000003239 151.0
PYH3_k127_8049268_11 response regulator, receiver - - - 0.00000000000000000000000000000001423 134.0
PYH3_k127_8049268_12 nucleotidyltransferase activity K07075 - - 0.0000000000000000000000000000004643 124.0
PYH3_k127_8049268_13 YoeB-like toxin of bacterial type II toxin-antitoxin system - - - 0.00000000000000000000000000001255 126.0
PYH3_k127_8049268_14 Protein of unknown function DUF86 - - - 0.00000000000000000000000000002343 121.0
PYH3_k127_8049268_15 response regulator, receiver - - - 0.000000000000000000000000001291 130.0
PYH3_k127_8049268_16 HIRAN - - - 0.000000000000000000000000002746 115.0
PYH3_k127_8049268_17 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000000000001459 119.0
PYH3_k127_8049268_18 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000002456 101.0
PYH3_k127_8049268_19 PIN domain - - - 0.000000000000000000002179 95.0
PYH3_k127_8049268_2 PFAM filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009465 407.0
PYH3_k127_8049268_20 mRNA binding K07339 - - 0.00000000000000000003749 98.0
PYH3_k127_8049268_21 heat shock protein binding K05516 - - 0.00000000000000004868 92.0
PYH3_k127_8049268_22 Protein of unknown function (DUF2283) - - - 0.000000000000002376 79.0
PYH3_k127_8049268_23 - - - - 0.0000000000162 69.0
PYH3_k127_8049268_24 - - - - 0.000000001065 66.0
PYH3_k127_8049268_25 WYL domain K13572 - - 0.000000001931 60.0
PYH3_k127_8049268_26 - - - - 0.00002552 51.0
PYH3_k127_8049268_27 - - - - 0.00004963 54.0
PYH3_k127_8049268_28 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00009637 49.0
PYH3_k127_8049268_3 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000552 379.0
PYH3_k127_8049268_4 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 357.0
PYH3_k127_8049268_5 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 299.0
PYH3_k127_8049268_6 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001985 265.0
PYH3_k127_8049268_7 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000476 261.0
PYH3_k127_8049268_8 PFAM Pyruvate phosphate dikinase, PEP K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000001782 209.0
PYH3_k127_8049268_9 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000003346 175.0
PYH3_k127_8058517_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 1.634e-201 668.0
PYH3_k127_8058517_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000001016 204.0
PYH3_k127_8058517_2 beta-N-acetylhexosaminidase K01207 - 3.2.1.52 0.000000000000000000000000000000000000000000000009718 184.0
PYH3_k127_8058517_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000003229 153.0
PYH3_k127_8058517_4 signal transduction histidine kinase - - - 0.000000000000000000000000000000000000002894 163.0
PYH3_k127_8058517_5 Ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000000000000000000000565 102.0
PYH3_k127_8058517_6 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.00000000000000008648 92.0
PYH3_k127_8058517_7 Glycoprotease family K01409,K14742 - 2.3.1.234 0.0000000000001988 78.0
PYH3_k127_8058517_8 Protein of unknown function (DUF465) - - - 0.000228 46.0
PYH3_k127_8076371_0 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005286 377.0
PYH3_k127_8076371_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000003261 220.0
PYH3_k127_8076371_2 Phosphoglycerate mutase family - - - 0.00000001919 59.0
PYH3_k127_8076371_3 - - - - 0.0000007365 52.0
PYH3_k127_8138030_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1054.0
PYH3_k127_8138030_1 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000003518 178.0
PYH3_k127_8138030_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000001151 68.0
PYH3_k127_8183688_0 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 333.0
PYH3_k127_8183688_1 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003403 323.0
PYH3_k127_8183688_2 Zinc carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009758 301.0
PYH3_k127_8183688_3 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002513 304.0
PYH3_k127_8183688_4 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000001624 239.0
PYH3_k127_8183688_5 Protein of unknown function (DUF1634) - - - 0.000000000000000004989 97.0
PYH3_k127_8183688_6 MOFRL family K11529 - 2.7.1.165 0.0000000000000009663 79.0
PYH3_k127_8183688_7 (FHA) domain - - - 0.000000000003095 73.0
PYH3_k127_8202249_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007661 559.0
PYH3_k127_8202249_1 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007496 245.0
PYH3_k127_8202249_2 heat shock protein binding - - - 0.000000000000000000000000000006658 121.0
PYH3_k127_8213935_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 324.0
PYH3_k127_8213935_1 CoA binding domain K06929 - - 0.00000000000000000000000000000004862 133.0
PYH3_k127_8213935_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000219 106.0
PYH3_k127_8213935_3 TIGRFAM TonB family C-terminal domain K03832 - - 0.0000000009612 71.0
PYH3_k127_8218570_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K03918 - 2.6.1.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 503.0
PYH3_k127_8218570_1 GAF domain - - - 0.000000000000000000000000000000000000000107 165.0
PYH3_k127_8218570_2 endoglucanase-related protein, glucosyl hydrolase family 9 protein - - - 0.00000000001008 79.0
PYH3_k127_8218570_3 Oxygen tolerance - - - 0.0005045 47.0
PYH3_k127_8222633_0 HlyD membrane-fusion protein of T1SS K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009164 429.0
PYH3_k127_8222633_1 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 422.0
PYH3_k127_8222633_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 424.0
PYH3_k127_8222633_3 Metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 308.0
PYH3_k127_8222633_4 PFAM Ion transport 2 domain protein - - - 0.00000000000000000000000000000000000000000009246 169.0
PYH3_k127_8222633_5 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.000000000000000000000000000000486 124.0
PYH3_k127_8222633_6 - - - - 0.000000000000000002148 90.0
PYH3_k127_8266347_0 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 442.0
PYH3_k127_8266347_1 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000256 233.0
PYH3_k127_8266347_2 Involved in the tonB-independent uptake of proteins - - - 0.0000000000000001283 91.0
PYH3_k127_8266347_3 Redoxin - - - 0.000000001296 68.0
PYH3_k127_8266347_4 PAS domain - - - 0.0002481 49.0
PYH3_k127_8304907_0 COGs COG2204 Response regulator containing CheY-like receiver AAA-type ATPase and DNA-binding domains K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004449 415.0
PYH3_k127_8304907_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000001837 197.0
PYH3_k127_8304907_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000001079 195.0
PYH3_k127_8304907_3 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000005976 105.0
PYH3_k127_8304907_4 - - - - 0.00000000001712 65.0
PYH3_k127_8304907_5 lipolytic protein G-D-S-L family - - - 0.00000000009835 74.0
PYH3_k127_8304907_6 3-demethylubiquinone-9 3-O-methyltransferase activity K00568 - 2.1.1.222,2.1.1.64 0.000000002186 63.0
PYH3_k127_8304907_7 - - - - 0.0004457 53.0
PYH3_k127_8310574_0 Glyceraldehyde-3-phosphate dehydrogenase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 380.0
PYH3_k127_8310574_1 OST-HTH/LOTUS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 344.0
PYH3_k127_8310574_2 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000009116 178.0
PYH3_k127_8310574_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000001352 159.0
PYH3_k127_8310574_4 PFAM Hemerythrin HHE cation binding domain protein - - - 0.0000000000000000000000000000000000001519 151.0
PYH3_k127_8310574_5 AMMECR1 K09141 - - 0.00000000000000000000000000000000008362 152.0
PYH3_k127_8310574_6 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000001324 140.0
PYH3_k127_8310574_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000003717 58.0
PYH3_k127_8367753_0 PFAM Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 8.841e-276 867.0
PYH3_k127_8367753_1 Carbamoyl-phosphate synthetase ammonia chain K01955 GO:0000050,GO:0000166,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005951,GO:0006082,GO:0006139,GO:0006206,GO:0006220,GO:0006221,GO:0006520,GO:0006525,GO:0006526,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016053,GO:0016597,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019627,GO:0019637,GO:0019693,GO:0019752,GO:0019856,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046394,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0071941,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 9.083e-195 623.0
PYH3_k127_8367753_2 Bacterial protein of unknown function (DUF937) - - - 0.000000000000000000000000000000000006962 143.0
PYH3_k127_8428052_0 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000001913 259.0
PYH3_k127_8428052_1 PFAM Orn DAP Arg decarboxylase 2 K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000001691 252.0
PYH3_k127_8428052_2 Methylmalonyl-CoA mutase K01848,K11942 - 5.4.99.13,5.4.99.2 0.0000000000000000000000000000000000000000000000002627 180.0
PYH3_k127_8428141_0 C-terminal, D2-small domain, of ClpB protein K11907 - - 3.5e-318 989.0
PYH3_k127_8428141_1 TIGRFAM type VI secretion system Vgr family protein K11904 - - 3.4e-205 668.0
PYH3_k127_8428141_2 Predicted methyltransferase regulatory domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 370.0
PYH3_k127_8428141_3 type VI secretion protein K11900,K11901 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 348.0
PYH3_k127_8428141_4 - - - - 0.00000000000000000000000000000000000000000000000000000002399 206.0
PYH3_k127_8428141_5 - - - - 0.000000000000000000000000000000000000000003699 169.0
PYH3_k127_8428141_6 PAAR motif - - - 0.00000000000000000008927 97.0
PYH3_k127_8458200_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000199 242.0
PYH3_k127_8464956_0 - - - - 0.0000000000000000000000000000000000000000000000000000000001647 226.0
PYH3_k127_8464956_1 Mycolic acid cyclopropane synthetase - - - 0.00000000000000000000000000000006776 130.0
PYH3_k127_8517792_0 Malic enzyme, NAD binding domain K00027 - 1.1.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 490.0
PYH3_k127_8517792_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 308.0
PYH3_k127_8517792_2 type I phosphodiesterase nucleotide pyrophosphatase - GO:0003674,GO:0003824,GO:0004035,GO:0004346,GO:0005488,GO:0005575,GO:0005623,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008877,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0042578,GO:0042597,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0046872,GO:0046914,GO:0050308,GO:0050309,GO:0098519 - 0.00000000000000000000000000000000000000000000000000001197 211.0
PYH3_k127_8517792_3 peptidyl-tyrosine sulfation - - - 0.000000495 62.0
PYH3_k127_8570626_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004572 522.0
PYH3_k127_8570626_1 Amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 323.0
PYH3_k127_8570626_2 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000003322 153.0
PYH3_k127_8570626_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000005154 135.0
PYH3_k127_8570626_4 methyltransferase activity - - - 0.00000000000000000000007985 112.0
PYH3_k127_8605719_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.785e-220 692.0
PYH3_k127_8605719_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 396.0
PYH3_k127_8605719_2 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 385.0
PYH3_k127_8605719_3 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002722 255.0
PYH3_k127_8605719_4 Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase K01227 - 3.2.1.96 0.00000000000000000000000000000000000001918 164.0
PYH3_k127_8605719_5 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.00000000000000000000007657 111.0
PYH3_k127_8605719_6 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000003562 80.0
PYH3_k127_8605719_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117,K03646 - - 0.00000000003116 76.0
PYH3_k127_8615914_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 388.0
PYH3_k127_8615914_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.000000000000000000000000000000000000000000000000005636 187.0
PYH3_k127_8615914_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000001279 162.0
PYH3_k127_8615914_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919,K16924 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000002471 124.0
PYH3_k127_8615914_4 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.0000000000000000000004159 104.0
PYH3_k127_8615914_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000008347 78.0
PYH3_k127_8631178_0 magnesium chelatase K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002536 544.0
PYH3_k127_8631178_1 - - - - 0.00000000000000000000000000000000000008698 150.0
PYH3_k127_8631678_0 Saccharopine dehydrogenase NADP binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 310.0
PYH3_k127_8631678_1 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000002886 208.0
PYH3_k127_8631678_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000001466 157.0
PYH3_k127_8631678_3 Catalyzes the biosynthesis of agmatine from arginine K01585 - 4.1.1.19 0.0000000000000000000000000000000000004396 145.0
PYH3_k127_8631678_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000002133 118.0
PYH3_k127_8631678_5 - - - - 0.00000000000000000162 96.0
PYH3_k127_8631678_6 nuclease activity K06218 - - 0.00000000000000002221 87.0
PYH3_k127_8642560_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 360.0
PYH3_k127_8642560_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000005101 132.0
PYH3_k127_8676768_0 Tfp pilus assembly protein, tip-associated adhesin PilY1 K02674 - - 0.000000000000000000005389 110.0
PYH3_k127_8717266_0 Amidohydrolase family K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000001657 217.0
PYH3_k127_8717266_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000006888 163.0
PYH3_k127_8717266_2 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749 - - 0.00000000000000003398 88.0
PYH3_k127_8717266_3 Sigma factor PP2C-like phosphatases K01079,K01768,K07315 - 3.1.3.3,4.6.1.1 0.0001577 53.0
PYH3_k127_8725024_0 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 376.0
PYH3_k127_8725024_1 Proline racemase K01777,K12658 - 5.1.1.4,5.1.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009628 337.0
PYH3_k127_8725024_2 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 318.0
PYH3_k127_8725024_3 Belongs to the DapA family K21062 - 3.5.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 326.0
PYH3_k127_8725024_4 Belongs to the aldehyde dehydrogenase family K22187 - - 0.0000000000000000000000000005539 114.0
PYH3_k127_8725024_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000003367 87.0
PYH3_k127_8731658_0 Molybdopterin oxidoreductase Fe4S4 domain K02567 - - 0.0 1316.0
PYH3_k127_8731658_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 471.0
PYH3_k127_8731658_2 oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 350.0
PYH3_k127_8731658_3 Uncharacterised protein family UPF0066 - - - 0.0000000000000000000000000000000000000000000000000000000000000000003922 232.0
PYH3_k127_8731658_4 YhhN family - - - 0.0000000000000000000000000000000000000002981 157.0
PYH3_k127_8731658_5 nuclear chromosome segregation - - - 0.0000000000000000000001124 109.0
PYH3_k127_8731658_6 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.00000000001207 69.0
PYH3_k127_8731658_7 protein involved in formation of periplasmic nitrate reductase K02570 - - 0.0000001684 64.0
PYH3_k127_8737187_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000001662 178.0
PYH3_k127_8737187_1 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000004156 69.0
PYH3_k127_8737187_2 Methyltransferase domain - - - 0.0000003364 61.0
PYH3_k127_8764657_0 PFAM Protein synthesis factor, GTP-binding K06207 - - 2.608e-244 770.0
PYH3_k127_8764657_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.0000000000000000000000000000000000000000002855 183.0
PYH3_k127_8764657_2 efflux transmembrane transporter activity - - - 0.00000000000000000000000000001522 137.0
PYH3_k127_8764657_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000003063 116.0
PYH3_k127_8764657_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000000000000000000003718 104.0
PYH3_k127_8764657_5 Covalently attaches a chromophore to Cys residue(s) of phycobiliproteins - - - 0.0000000000000000000000161 108.0
PYH3_k127_8764657_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000007598 78.0
PYH3_k127_8764657_9 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0001697 46.0
PYH3_k127_8783505_0 FGGY family of carbohydrate kinases, N-terminal domain - - - 3.606e-244 764.0
PYH3_k127_8783505_1 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 467.0
PYH3_k127_8783505_2 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.000000000000000000000000000000000000000001275 162.0
PYH3_k127_8783505_3 - - - - 0.0000000000000000000000000000000000001009 150.0
PYH3_k127_8783505_4 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000004828 143.0
PYH3_k127_8783505_5 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.0000000000000000000000008377 106.0
PYH3_k127_8783505_6 regulator - - - 0.0000000000000000000000508 104.0
PYH3_k127_8783505_7 aspartate kinase activity - - - 0.0000000001028 68.0
PYH3_k127_8783505_8 Pfam Response regulator receiver - - - 0.000000001079 63.0
PYH3_k127_8799029_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006248 562.0
PYH3_k127_8799029_1 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 0.00000000000000000000000000000000000000000000000000000000000000000009789 255.0
PYH3_k127_8803638_0 IgA Peptidase M64 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004031 479.0
PYH3_k127_8803638_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009632 261.0
PYH3_k127_8803638_2 methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000003682 225.0
PYH3_k127_8803638_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000367 153.0
PYH3_k127_8803638_4 ABC-2 family transporter protein - - - 0.00000000000000000000000000000000006384 149.0
PYH3_k127_8803638_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000001055 102.0
PYH3_k127_8808774_0 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 311.0
PYH3_k127_8808774_1 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000006878 239.0
PYH3_k127_8808774_2 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.00000000000000000000000000003221 122.0
PYH3_k127_8813781_0 PFAM Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 1.167e-198 631.0
PYH3_k127_8813781_1 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 426.0
PYH3_k127_8813781_2 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 413.0
PYH3_k127_8813781_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 383.0
PYH3_k127_8813781_4 PFAM Thymidine kinase K00857 - 2.7.1.21 0.00000000000000000000000000000000000000000000000000000000000000001725 242.0
PYH3_k127_8813781_5 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000007201 247.0
PYH3_k127_8813781_6 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000009781 89.0
PYH3_k127_8813781_7 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000007992 63.0
PYH3_k127_8813781_8 Domain of unknown function (DUF4388) - - - 0.0000001394 63.0
PYH3_k127_8826493_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000003833 136.0
PYH3_k127_8826493_1 Tetratricopeptide repeat - - - 0.00000000000000000000000004216 125.0
PYH3_k127_8826493_2 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000001724 120.0
PYH3_k127_8831713_0 3-isopropylmalate dehydratase activity K01703 - 4.2.1.33,4.2.1.35 8.011e-215 673.0
PYH3_k127_8831713_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 599.0
PYH3_k127_8831713_2 Isocitrate/isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 560.0
PYH3_k127_8831713_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 398.0
PYH3_k127_8831713_4 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 369.0
PYH3_k127_8831713_5 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000001455 251.0
PYH3_k127_8831713_6 3-isopropylmalate dehydratase activity K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000001845 198.0
PYH3_k127_8831713_8 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000001548 139.0
PYH3_k127_8831713_9 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.00000000000000000008151 90.0
PYH3_k127_892233_0 Domain of Unknown Function (DUF748) - - - 5.586e-201 670.0
PYH3_k127_892233_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000287 536.0
PYH3_k127_892233_2 Bacterial regulatory protein, Fis family K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 364.0
PYH3_k127_892233_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 376.0
PYH3_k127_892233_4 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000004914 202.0
PYH3_k127_892233_5 signal transduction histidine kinase K02668,K07709 - 2.7.13.3 0.0000000000000000000005309 111.0
PYH3_k127_892233_6 Rhomboid family - - - 0.0000000000000001284 91.0
PYH3_k127_892233_7 Protein of unknown function (DUF1579) - - - 0.00000000004339 70.0
PYH3_k127_892233_8 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000009651 52.0
PYH3_k127_892233_9 - - - - 0.00001416 56.0
PYH3_k127_8929498_0 SMART PDZ DHR GLGF domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 428.0
PYH3_k127_8929498_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 334.0
PYH3_k127_8929498_2 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000005291 197.0
PYH3_k127_8929498_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000006396 135.0
PYH3_k127_90033_0 PFAM Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005076 250.0
PYH3_k127_90033_1 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000001228 241.0
PYH3_k127_90033_2 signal transduction histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000373 246.0
PYH3_k127_90033_3 K COG5665 CCR4-NOT transcriptional regulation complex, NOT5 subunit - - - 0.000000000000000000000000000000000001491 148.0
PYH3_k127_90033_4 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K04085 - - 0.00000000000000000000000000001852 119.0
PYH3_k127_90033_5 Integrase core domain K07497 - - 0.0000000000000000000003479 108.0
PYH3_k127_9032427_0 NAD synthase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 556.0
PYH3_k127_9032427_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003781 528.0
PYH3_k127_9032427_2 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000001151 265.0
PYH3_k127_9032427_3 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000001887 216.0
PYH3_k127_9032427_4 Psort location Cytoplasmic, score 8.96 K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000003951 170.0
PYH3_k127_9032427_5 PIN domain - - - 0.000000000000000000000000000000001165 135.0
PYH3_k127_9032427_6 Glycosyl transferase family 2 - - - 0.00000000000000000000000000003445 136.0
PYH3_k127_9032427_7 Antitoxin Phd_YefM, type II toxin-antitoxin system - - - 0.000000000000009717 77.0
PYH3_k127_9032427_8 RDD family - - - 0.00003094 54.0
PYH3_k127_9035822_0 Alpha amylase, catalytic domain K01176 - 3.2.1.1 3.871e-195 623.0
PYH3_k127_9035822_1 Aminotransferase class I and II K14267 - 2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 435.0
PYH3_k127_9035822_2 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001184 298.0
PYH3_k127_9035822_3 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.00000000000000000000004311 108.0
PYH3_k127_9035822_4 Protein of unknown function, DUF255 K01829 - 5.3.4.1 0.0000000000003384 76.0
PYH3_k127_9136726_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000005283 244.0
PYH3_k127_9136726_1 Aminotransferase class-III - - - 0.0000000000000000000000735 115.0
PYH3_k127_9136726_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000158 91.0
PYH3_k127_9136726_3 PFAM peptidase - - - 0.000000000000001679 87.0
PYH3_k127_9189806_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000002855 60.0
PYH3_k127_9189806_1 toxin-antitoxin pair type II binding K06284 - - 0.00001801 51.0
PYH3_k127_9191430_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 533.0
PYH3_k127_9221530_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.154e-281 876.0
PYH3_k127_9221530_1 DEAD DEAH box helicase - - - 6.95e-265 846.0
PYH3_k127_9221530_10 MlaD protein K02067 - - 0.0000000000000000000000000000000000007216 154.0
PYH3_k127_9221530_11 Dodecin K09165 - - 0.00000000000000000000000285 105.0
PYH3_k127_9221530_12 CHASE - - - 0.000000000000000000001119 111.0
PYH3_k127_9221530_13 PFAM cytochrome c assembly protein K02198 - - 0.00000000000102 77.0
PYH3_k127_9221530_14 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000001518 56.0
PYH3_k127_9221530_2 Involved in the tonB-independent uptake of proteins K08884,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005084 569.0
PYH3_k127_9221530_3 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 345.0
PYH3_k127_9221530_4 serine-type endopeptidase inhibitor activity K13963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 307.0
PYH3_k127_9221530_5 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000009456 239.0
PYH3_k127_9221530_6 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000001795 253.0
PYH3_k127_9221530_7 - - - - 0.000000000000000000000000000000000000000000000000000000003388 208.0
PYH3_k127_9221530_8 Domains REC, PAS, PAS, PP2C K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000001634 224.0
PYH3_k127_9221530_9 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000000000000000000659 161.0
PYH3_k127_9267498_0 PFAM Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 524.0
PYH3_k127_9267498_1 Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA K00639 - 2.3.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 438.0
PYH3_k127_9267498_10 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0004832 49.0
PYH3_k127_9267498_2 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000316 203.0
PYH3_k127_9267498_3 PFAM short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000001032 199.0
PYH3_k127_9267498_4 phosphatase activity K07025 - - 0.0000000000000000000000000000000000001232 156.0
PYH3_k127_9267498_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.00000000000000000000000000000000003019 149.0
PYH3_k127_9267498_6 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.000000000000000000000000000000001055 145.0
PYH3_k127_9267498_7 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03635,K21142 - 2.8.1.12 0.0000000000003501 72.0
PYH3_k127_9267498_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000008023 74.0
PYH3_k127_9267498_9 PIN domain K07064 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040008,GO:0044464,GO:0045926,GO:0048519,GO:0050789,GO:0065007,GO:0071944 - 0.0000000002107 69.0
PYH3_k127_9286198_0 Transketolase, pyrimidine binding domain K11381 - 1.2.4.4 8.98e-272 853.0
PYH3_k127_9286198_1 Protein of unknown function (DUF2911) - - - 0.0000000000000000008266 88.0
PYH3_k127_9309385_0 Urocanase C-terminal domain K01712 - 4.2.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001526 298.0
PYH3_k127_9309385_1 PFAM phospholipid glycerol acyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007443 310.0
PYH3_k127_9309385_2 PFAM Patatin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006812 280.0
PYH3_k127_9309385_3 NAD dependent epimerase/dehydratase family K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000005358 218.0
PYH3_k127_9309385_4 NAD(P)H-binding - - - 0.000000000000000000000000000000000000000000000000000000002291 209.0
PYH3_k127_9309385_5 anion-transporting ATPase - - - 0.000000000000000000000000000000000003647 158.0
PYH3_k127_9309385_6 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000004129 136.0
PYH3_k127_9309385_7 PFAM PHA accumulation regulator DNA-binding protein - - - 0.0000002031 60.0
PYH3_k127_9318339_0 WD40-like Beta Propeller Repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 397.0
PYH3_k127_9318339_1 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000006634 240.0
PYH3_k127_9318339_2 Fe-S protein K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000005954 202.0
PYH3_k127_9318339_3 permease - - - 0.0000000000000000000000000000000000000000000001804 184.0
PYH3_k127_9372085_0 PFAM Prolyl oligopeptidase family - - - 1.222e-241 771.0
PYH3_k127_9372085_1 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 374.0
PYH3_k127_9372085_2 imidazolonepropionase activity K01443 - 3.5.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000234 293.0
PYH3_k127_9372085_3 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000002196 167.0
PYH3_k127_9372085_4 Transcription elongation factor, N-terminal - - - 0.00000000000000000000000000003728 135.0
PYH3_k127_9375219_0 transporter, DctM subunit K11690 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 394.0
PYH3_k127_9408118_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 6.982e-197 637.0
PYH3_k127_9408118_1 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002802 547.0
PYH3_k127_9408118_2 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002195 372.0
PYH3_k127_9408118_3 NAD(P)H binding domain of trans-2-enoyl-CoA reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 338.0
PYH3_k127_9408118_4 Protein of unknown function, DUF547 - - - 0.00000000000000000002442 101.0
PYH3_k127_9408118_5 PIN domain K19686 - - 0.00000000000000000002618 91.0
PYH3_k127_9408118_6 Homocysteine S-methyltransferase K00547 - 2.1.1.10 0.000000000007728 70.0
PYH3_k127_9408118_7 Tetratricopeptide repeat - - - 0.00058 51.0
PYH3_k127_9448197_0 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 396.0
PYH3_k127_9448197_1 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000001075 215.0
PYH3_k127_9448197_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000001264 225.0
PYH3_k127_9448197_3 von Willebrand factor, type A - - - 0.000000000000000000001203 106.0
PYH3_k127_9448197_4 Thrombospondin type 3 repeat K03286 - - 0.000000000000002056 84.0
PYH3_k127_9450545_0 Belongs to the UbiD family K03182,K16239 - 4.1.1.61,4.1.1.98 7.472e-220 696.0
PYH3_k127_9450545_1 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 516.0
PYH3_k127_9450545_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000001808 93.0
PYH3_k127_9450545_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.000000005087 68.0
PYH3_k127_9459297_0 FAD linked oxidases, C-terminal domain K00104,K18930 - 1.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003237 404.0
PYH3_k127_9459297_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 312.0
PYH3_k127_9459297_2 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006662 248.0
PYH3_k127_9459297_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000002174 235.0
PYH3_k127_9459297_4 AI-2E family transporter - - - 0.0000000000000000000000000000005547 137.0
PYH3_k127_9459297_5 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000001593 96.0
PYH3_k127_9459297_6 chlorophyll binding - - - 0.0000002007 58.0
PYH3_k127_94871_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 475.0
PYH3_k127_94871_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 335.0
PYH3_k127_94871_2 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004749 299.0
PYH3_k127_94871_3 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.0000000000000000000000000003794 118.0
PYH3_k127_94871_4 ABC transporter K01990 - - 0.0000000000000001507 91.0
PYH3_k127_9491419_0 Heat shock 70 kDa protein K04043 - - 5.498e-290 902.0
PYH3_k127_9491419_1 TIGRFAM MazG family protein K02428,K04765 - 3.6.1.66,3.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000007934 246.0
PYH3_k127_9491419_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000004249 195.0
PYH3_k127_9491419_3 IstB-like ATP binding protein K02315 - - 0.0000000000000000000000000000000000000000000000002049 184.0
PYH3_k127_9491419_4 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000007957 195.0
PYH3_k127_9491419_5 PFAM regulatory protein, MerR K13640 - - 0.00000000000000000000000000005574 121.0
PYH3_k127_9491419_6 Tetratricopeptide repeat - - - 0.00000000000000000000000000008863 134.0
PYH3_k127_9491419_7 Divergent polysaccharide deacetylase K09798 - - 0.000007581 49.0
PYH3_k127_9491419_8 Domain of unknown function (DUF1844) - - - 0.0000417 51.0
PYH3_k127_9521618_0 PFAM Nitrate reductase gamma subunit K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 383.0
PYH3_k127_9521618_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000001691 221.0
PYH3_k127_9521618_2 DsrC like protein K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000002637 171.0
PYH3_k127_9521618_3 RsbT co-antagonist protein rsbRD N-terminal domain - - - 0.00000000000000000000001599 108.0
PYH3_k127_9521618_4 Tetratricopeptide TPR_1 repeat-containing protein - - - 0.0000000000001646 78.0
PYH3_k127_9521618_5 HEAT-like repeat - - - 0.00000006636 64.0
PYH3_k127_9523414_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 2.818e-214 686.0
PYH3_k127_9523414_1 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000003949 239.0
PYH3_k127_9523414_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000005019 104.0
PYH3_k127_9523414_3 Protein of unknown function (DUF503) K09764 - - 0.00000000008684 67.0
PYH3_k127_9533590_0 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 349.0
PYH3_k127_9533590_1 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003315 278.0
PYH3_k127_9533590_2 KH domain K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004164 265.0
PYH3_k127_9533590_3 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000001491 115.0
PYH3_k127_9533590_4 MacB-like periplasmic core domain K02004 - - 0.00000000002734 65.0
PYH3_k127_95879_0 B12 binding domain - - - 2.312e-248 776.0
PYH3_k127_95879_1 Radical SAM - - - 2.467e-203 670.0
PYH3_k127_95879_2 Polyphosphate kinase middle domain K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006777 598.0
PYH3_k127_95879_3 Aminotransferase class-V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 574.0
PYH3_k127_95879_4 Glycosyl transferase family group 2 K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000001247 269.0
PYH3_k127_95879_5 Domain of unknown function (DUF3943) - - - 0.0000000000000000000000000000000000000000000000000000003039 218.0
PYH3_k127_95879_6 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000008238 203.0
PYH3_k127_95879_7 lysyltransferase activity K07027 - - 0.0000000000000000000003895 109.0
PYH3_k127_9693219_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 308.0
PYH3_k127_9693219_1 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.00000000000000000000000000000000000002287 148.0
PYH3_k127_9717216_0 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000002486 216.0
PYH3_k127_9717216_1 amine dehydrogenase activity - - - 0.00000000000000000000000001224 128.0
PYH3_k127_9717216_2 lipolytic protein G-D-S-L family - - - 0.000000000001583 79.0
PYH3_k127_9717216_3 - - - - 0.00002211 54.0
PYH3_k127_9717216_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0004617 54.0
PYH3_k127_9717216_5 glycosyl transferase, family 39 - - - 0.0009719 52.0
PYH3_k127_9729172_0 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006312 471.0
PYH3_k127_9729172_1 carbon starvation protein CstA K06200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005144 410.0
PYH3_k127_9729172_2 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000000000001602 149.0
PYH3_k127_9729172_3 - - - - 0.0000000000000000000000000000000005819 133.0
PYH3_k127_9729172_4 - - - - 0.0000000000000009668 88.0
PYH3_k127_9729172_5 Protein of unknown function (DUF1501) - - - 0.00000000000001494 79.0
PYH3_k127_9729172_6 - - - - 0.00003979 53.0
PYH3_k127_973437_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.751e-233 741.0
PYH3_k127_973437_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000002479 212.0
PYH3_k127_973437_2 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000005083 122.0
PYH3_k127_9771863_0 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 450.0
PYH3_k127_9771863_1 Protein of unknown function (DUF3300) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 361.0
PYH3_k127_9771863_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - GO:0005575,GO:0005576 - 0.0000000000000000000000000000000000000000007078 163.0
PYH3_k127_9771863_11 - - - - 0.00000000000000000000000003834 123.0
PYH3_k127_9771863_12 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.000000000000000000004395 106.0
PYH3_k127_9771863_14 toxin-antitoxin pair type II binding - - - 0.000000000000006788 81.0
PYH3_k127_9771863_15 toxin-antitoxin pair type II binding K06284 - - 0.000008651 57.0
PYH3_k127_9771863_16 - - - - 0.0001589 49.0
PYH3_k127_9771863_17 permease - - - 0.0003094 52.0
PYH3_k127_9771863_18 - - - - 0.0009758 51.0
PYH3_k127_9771863_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 328.0
PYH3_k127_9771863_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 323.0
PYH3_k127_9771863_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003602 310.0
PYH3_k127_9771863_5 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002216 252.0
PYH3_k127_9771863_6 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000154 250.0
PYH3_k127_9771863_7 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000004472 254.0
PYH3_k127_9771863_8 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000006341 231.0
PYH3_k127_9771863_9 dna-binding protein - - - 0.0000000000000000000000000000000000000000000000000001617 188.0