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Overview

ID MAG03213
Name PYH3_bin.14
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Desulfobacterota
Class Syntrophobacteria
Order BM002
Family BM002
Genus JAGFXI01
Species
Assembly information
Completeness (%) 81.59
Contamination (%) 4.22
GC content (%) 61.0
N50 (bp) 4,847
Genome size (bp) 2,458,680

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2324

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1028399_0 PFAM Acyl-CoA dehydrogenase K19066,K19067 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0022607,GO:0036094,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0048037,GO:0050660,GO:0050662,GO:0051259,GO:0051262,GO:0052890,GO:0055114,GO:0065003,GO:0071840,GO:0097159,GO:1901265,GO:1901363 1.3.8.10,1.3.8.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 508.0
PYH3_k127_1028399_1 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 463.0
PYH3_k127_1028399_2 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000002109 180.0
PYH3_k127_1045211_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 414.0
PYH3_k127_1045211_1 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000002538 136.0
PYH3_k127_1045475_0 glycosyl transferase family 2 K21349 - 2.4.1.268 0.0000000000000000000000000000000000000000000000000000000000000000000001449 245.0
PYH3_k127_1045475_1 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000003467 169.0
PYH3_k127_1056771_0 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 572.0
PYH3_k127_1056771_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 444.0
PYH3_k127_1056771_2 nucleotide metabolic process - - - 0.0000000000000000000000000000000000000000000005663 174.0
PYH3_k127_1083702_0 PIN domain - - - 0.0000000000000000000000000000000000000000000000002018 180.0
PYH3_k127_1083702_1 InterPro IPR008538 - - - 0.000000000000000000000000000000000001292 143.0
PYH3_k127_1083702_2 InterPro IPR008538 - - - 0.000000000000000000000000004803 112.0
PYH3_k127_1083702_3 cheY-homologous receiver domain - - - 0.000000000005249 72.0
PYH3_k127_1083702_5 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000001848 63.0
PYH3_k127_1083702_6 - - - - 0.000000276 54.0
PYH3_k127_1083702_7 COGs COG4636 conserved - - - 0.00001629 48.0
PYH3_k127_1083702_8 COG2801 Transposase and inactivated derivatives K07497 - - 0.00004626 46.0
PYH3_k127_1112239_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007926 529.0
PYH3_k127_1112239_1 MgtE intracellular - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 393.0
PYH3_k127_1112239_2 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 376.0
PYH3_k127_1112239_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.0000000000000001643 81.0
PYH3_k127_112343_0 transport system permease component K02037 - - 2.241e-261 824.0
PYH3_k127_1127926_0 thiamine biosynthesis protein ThiC K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 557.0
PYH3_k127_1127926_1 isochorismatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005295 486.0
PYH3_k127_1127926_2 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001903 402.0
PYH3_k127_1127926_3 Xylose isomerase-like TIM barrel K01151 GO:0003674,GO:0003824,GO:0003906,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008081,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0033554,GO:0034641,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 355.0
PYH3_k127_1127926_4 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00001032 50.0
PYH3_k127_1127926_5 - - - - 0.0003215 45.0
PYH3_k127_1138891_0 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002931 538.0
PYH3_k127_1138891_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
PYH3_k127_1138891_2 HlyD family secretion protein K01993 - - 0.0000000000000000000001918 98.0
PYH3_k127_117787_0 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 1.455e-238 763.0
PYH3_k127_117787_1 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 465.0
PYH3_k127_1180028_0 TIGRFAM clan AA aspartic protease, AF_0612 family - - - 0.0000000000000000000000000000000000000000000000009549 176.0
PYH3_k127_1180028_1 DNA integration - - - 0.000000000000000000000000000000000000000000001011 172.0
PYH3_k127_1180028_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.00000000000000000000000000000000002163 141.0
PYH3_k127_1180028_3 - - - - 0.0000000000000000000000000265 116.0
PYH3_k127_1180028_4 CHAT domain - - - 0.00000000000000000000004018 102.0
PYH3_k127_1184688_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.042e-290 908.0
PYH3_k127_1184688_1 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007497 541.0
PYH3_k127_1184688_2 Rad51 K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 529.0
PYH3_k127_1184688_3 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 454.0
PYH3_k127_1184688_4 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 387.0
PYH3_k127_1184688_5 TIGRFAM competence damage-inducible protein CinA K03742,K03743 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 295.0
PYH3_k127_1184688_6 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.000000000000000000000000000000000000000000000000000000000000000000005803 241.0
PYH3_k127_1184688_7 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000000000000000003318 176.0
PYH3_k127_1184688_8 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008962,GO:0009058,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016021,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0030258,GO:0031224,GO:0031226,GO:0032026,GO:0042221,GO:0042577,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044425,GO:0044459,GO:0044464,GO:0045017,GO:0046471,GO:0046474,GO:0046486,GO:0046839,GO:0050896,GO:0071704,GO:0071944,GO:0090407,GO:1901576 3.1.3.27 0.0000000000000000000000000000008018 129.0
PYH3_k127_1184688_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000001743 106.0
PYH3_k127_1186542_0 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 578.0
PYH3_k127_1186542_1 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 407.0
PYH3_k127_1186542_2 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007581 263.0
PYH3_k127_1186542_3 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000002912 222.0
PYH3_k127_1186542_4 AsmA-like C-terminal region K07290 - - 0.000000001476 61.0
PYH3_k127_1207423_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006426 456.0
PYH3_k127_1207423_1 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074,K15016 - 1.1.1.157,1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 404.0
PYH3_k127_1214372_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 342.0
PYH3_k127_1214372_1 Belongs to the sulfur carrier protein TusA family - - - 0.000000000000000000000000000000000000000000000000000000000001876 214.0
PYH3_k127_1214372_2 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000001305 142.0
PYH3_k127_1214372_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000009667 115.0
PYH3_k127_1231190_0 PFAM transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 513.0
PYH3_k127_1231190_1 Domain of unknown function (DUF4338) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 361.0
PYH3_k127_1231190_2 PFAM IS66 Orf2 family protein K07484 - - 0.00000000000000000000000000000000000000000005498 165.0
PYH3_k127_1231190_3 - - - - 0.00000003828 60.0
PYH3_k127_1236190_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 381.0
PYH3_k127_1236190_1 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 386.0
PYH3_k127_1236190_2 HpcH/HpaI aldolase/citrate lyase family K00979,K01630,K02510 - 2.7.7.38,4.1.2.20,4.1.2.52 0.000000000000000000000000000000000000000000000000000000000000000000000000069 256.0
PYH3_k127_1236190_3 AdP-ribose pyrophosphatase K01515 - 3.6.1.13 0.0000000000000000000000000003122 123.0
PYH3_k127_1236190_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000005871 87.0
PYH3_k127_1244854_0 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003704 402.0
PYH3_k127_1244854_1 MutS domain I K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000004691 158.0
PYH3_k127_1244854_2 PFAM ribonuclease II K01147,K12573 - 3.1.13.1 0.0000000001766 65.0
PYH3_k127_1294153_0 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001913 537.0
PYH3_k127_1294153_1 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 313.0
PYH3_k127_1294153_2 Glycine-zipper domain - - - 0.0000000000000000002621 89.0
PYH3_k127_1294153_3 Glycine-zipper domain - - - 0.000000001272 67.0
PYH3_k127_1308371_0 two component, sigma54 specific, transcriptional regulator, Fis family K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 520.0
PYH3_k127_1308371_1 PFAM MgsA AAA ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 507.0
PYH3_k127_1308371_2 Signal transduction histidine kinase, nitrogen specific - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 459.0
PYH3_k127_1308371_3 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000549 165.0
PYH3_k127_1308371_4 Tetratricopeptide repeat - - - 0.000000008829 64.0
PYH3_k127_1309632_0 PFAM type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000004131 212.0
PYH3_k127_1309632_1 SMART AAA ATPase K02450 - - 0.0000000000000000000000000000000000000000000000000000005823 212.0
PYH3_k127_1309632_2 Pfam:N_methyl_2 K02458 - - 0.0000000001018 69.0
PYH3_k127_1309632_3 protein transport across the cell outer membrane K02457,K08084 - - 0.0000000001346 71.0
PYH3_k127_1309632_4 general secretion pathway protein K02457,K02459,K10927,K12285 - - 0.0000000006397 68.0
PYH3_k127_1309632_5 PFAM type II secretion system K02455,K02653 - - 0.000000001435 59.0
PYH3_k127_1312107_0 Silent information regulator protein Sir2 - - - 0.000000000000000000000000000000000000000000000000000000000000000001155 230.0
PYH3_k127_1312107_1 hydrolase - - - 0.0000000000000000000000000000000000000000000000000001453 194.0
PYH3_k127_1312107_2 - - - - 0.000000000000000000000000000000002732 138.0
PYH3_k127_1317904_0 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005025 449.0
PYH3_k127_1317904_1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0000000000000000000000000000000000000000000001604 168.0
PYH3_k127_1325569_0 - - - - 0.0000000000000000000000000000000000000000000006889 171.0
PYH3_k127_1325569_1 PFAM Formiminotransferase-cyclodeaminase - - - 0.00000000000000000000000000000000000000003215 159.0
PYH3_k127_1329771_0 Polysaccharide biosynthesis C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004341 285.0
PYH3_k127_136202_0 ABC transporter K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 364.0
PYH3_k127_136202_1 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 351.0
PYH3_k127_136202_2 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001067 278.0
PYH3_k127_136202_3 amino acid ABC transporter K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003212 275.0
PYH3_k127_136202_4 helix_turn_helix ASNC type K03718 - - 0.000000000000000000001743 96.0
PYH3_k127_1365299_0 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001607 316.0
PYH3_k127_1365299_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000003138 213.0
PYH3_k127_1365299_2 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000000000000000000000000000000000000006474 180.0
PYH3_k127_1365299_3 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000007405 132.0
PYH3_k127_1367369_0 AcrB/AcrD/AcrF family K03296,K18138 - - 0.0 1691.0
PYH3_k127_1367369_1 HlyD family secretion protein K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 495.0
PYH3_k127_1367369_10 Saccharopine dehydrogenase C-terminal domain - - - 0.000000000000000000000003667 103.0
PYH3_k127_1367369_2 PFAM MmgE PrpD family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 434.0
PYH3_k127_1367369_3 COG1593 TRAP-type C4-dicarboxylate transport system large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 399.0
PYH3_k127_1367369_4 Cytochrome C biogenesis protein transmembrane region K04084 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008891 379.0
PYH3_k127_1367369_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 347.0
PYH3_k127_1367369_6 7TM receptor with intracellular HD hydrolase K07037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007626 278.0
PYH3_k127_1367369_7 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000001113 161.0
PYH3_k127_1367369_8 - - - - 0.0000000000000000000000000000000002939 132.0
PYH3_k127_1367369_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000007187 112.0
PYH3_k127_1369125_0 TIGRFAM leucyl-tRNA synthetase K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1150.0
PYH3_k127_1369125_1 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 7.303e-200 628.0
PYH3_k127_1369125_10 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000001564 233.0
PYH3_k127_1369125_11 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000001067 224.0
PYH3_k127_1369125_12 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000001792 197.0
PYH3_k127_1369125_13 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000002484 149.0
PYH3_k127_1369125_14 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000004947 130.0
PYH3_k127_1369125_15 Lipopolysaccharide-assembly - - - 0.000000000000000000001705 103.0
PYH3_k127_1369125_16 Binds directly to 16S ribosomal RNA K02968 - - 0.00000000000003521 77.0
PYH3_k127_1369125_17 PFAM thioesterase superfamily protein - - - 0.000000000002366 72.0
PYH3_k127_1369125_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 598.0
PYH3_k127_1369125_3 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004888 592.0
PYH3_k127_1369125_4 electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 486.0
PYH3_k127_1369125_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
PYH3_k127_1369125_6 acyl-coa dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 362.0
PYH3_k127_1369125_7 PFAM Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003266 344.0
PYH3_k127_1369125_8 Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 309.0
PYH3_k127_1369125_9 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001974 235.0
PYH3_k127_1374007_0 formylmethanofuran dehydrogenase, subunit E region K11261 - 1.2.7.12 2.431e-250 782.0
PYH3_k127_1374007_1 - - - - 0.00000000000000000000000000000000000000000000000000000003981 201.0
PYH3_k127_137741_0 PFAM Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008105 556.0
PYH3_k127_137741_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 446.0
PYH3_k127_137741_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004294 283.0
PYH3_k127_137741_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000002316 219.0
PYH3_k127_137741_4 Electron transfer flavoprotein domain K03521 - - 0.0000000001753 64.0
PYH3_k127_1403273_0 Glutamine phosphoribosylpyrophosphate amidotransferase K00764 - 2.4.2.14 4.462e-204 644.0
PYH3_k127_1403273_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 491.0
PYH3_k127_1403273_2 Aldolase/RraA - - - 0.0000000000000000000000000000000000000000000000000000612 195.0
PYH3_k127_1403273_3 positive regulation of growth rate - - - 0.00000284 54.0
PYH3_k127_1409355_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 420.0
PYH3_k127_1409355_1 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000002966 154.0
PYH3_k127_1462113_0 - - - - 0.00000000000000000000000000000000000005643 148.0
PYH3_k127_1462113_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000003024 143.0
PYH3_k127_1462113_2 Cupin 2, conserved barrel domain protein - - - 0.0000000002168 68.0
PYH3_k127_1462113_3 Acetyltransferase (GNAT) domain - GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 - 0.00000008111 53.0
PYH3_k127_1471509_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2231.0
PYH3_k127_1471509_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 7.568e-313 970.0
PYH3_k127_1471509_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000001602 237.0
PYH3_k127_1471509_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000009038 231.0
PYH3_k127_1471509_4 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000179 76.0
PYH3_k127_14780_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 586.0
PYH3_k127_14780_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001019 236.0
PYH3_k127_14780_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000001215 224.0
PYH3_k127_14780_3 Acylphosphatase K01512 - 3.6.1.7 0.00000000000000000000000001256 111.0
PYH3_k127_1487492_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 346.0
PYH3_k127_1487492_1 Beta-lactamase enzyme family K07258,K07262 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001549 268.0
PYH3_k127_1487492_2 - - - - 0.0000000003523 60.0
PYH3_k127_1487492_3 ArsR family transcriptional regulator K07658 - - 0.00000009838 55.0
PYH3_k127_1487492_4 Response regulator receiver domain protein - - - 0.0002224 46.0
PYH3_k127_1487937_0 DSHCT - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003887 578.0
PYH3_k127_1487937_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004398 530.0
PYH3_k127_1487937_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 339.0
PYH3_k127_1487937_3 PFAM phosphotransferase KptA Tpt1 K07559 - - 0.000000000000000000000000000000001936 141.0
PYH3_k127_1487937_4 Replication protein - - - 0.0000000000000000000007182 104.0
PYH3_k127_1487937_5 Smr domain - - - 0.00000000000000000003198 100.0
PYH3_k127_1509672_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 431.0
PYH3_k127_1509672_1 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001388 282.0
PYH3_k127_1509672_2 Ribosomal protein L11 methyltransferase (PrmA) K15460 - 2.1.1.223 0.000000000000000000000000000000000000000000000000000000000004872 216.0
PYH3_k127_1509672_3 Bacterial regulatory protein, Fis family - - - 0.00000000000000002467 84.0
PYH3_k127_1509672_4 - - - - 0.0000000000004933 70.0
PYH3_k127_1509672_5 Protein of unknown function (DUF721) - - - 0.0000000001037 68.0
PYH3_k127_1510730_0 BadF BadG BcrA BcrD - - - 1.425e-268 844.0
PYH3_k127_1510730_1 Transcriptional regulator, MerR family - - - 0.000000000000000000000000000000000000000000000000000000000001474 213.0
PYH3_k127_1510730_2 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000003868 70.0
PYH3_k127_1535310_0 Alpha amylase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 608.0
PYH3_k127_1535310_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000001148 119.0
PYH3_k127_1535310_2 Plasmid stability protein K21495 - - 0.00000000000003972 74.0
PYH3_k127_1535310_3 Glycine-zipper domain - - - 0.000002145 55.0
PYH3_k127_153849_0 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 306.0
PYH3_k127_153849_1 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000000000000000000000000007033 235.0
PYH3_k127_153849_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000001747 236.0
PYH3_k127_1583492_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 2.392e-210 663.0
PYH3_k127_1583492_1 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008976 542.0
PYH3_k127_1583492_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007898 445.0
PYH3_k127_1583492_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 354.0
PYH3_k127_1583492_4 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 345.0
PYH3_k127_1583492_5 Conserved protein K01163 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007518 280.0
PYH3_k127_1583492_6 transcriptional regulator, AsnC family - - - 0.000000000000000000000000000000000000000000000000001439 188.0
PYH3_k127_1583492_7 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000000000000000001038 139.0
PYH3_k127_1583492_8 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000002258 120.0
PYH3_k127_1583492_9 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.000000000005627 69.0
PYH3_k127_1589280_0 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 410.0
PYH3_k127_1589280_1 Type II transport protein GspH K08084 - - 0.00000000002473 72.0
PYH3_k127_159538_0 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 4.353e-221 701.0
PYH3_k127_159538_1 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000005249 199.0
PYH3_k127_159538_2 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000000000000000000000000000000000000000000000000004353 197.0
PYH3_k127_159538_3 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.00000000000000000000000000000000000000000009494 166.0
PYH3_k127_159538_4 PFAM sigma-54 factor interaction domain-containing protein - - - 0.00000000002651 68.0
PYH3_k127_159538_5 NfeD-like C-terminal, partner-binding - - - 0.0000000007431 61.0
PYH3_k127_16160_0 Belongs to the ClpX chaperone family - - - 1.183e-223 707.0
PYH3_k127_16160_1 PFAM Radical SAM K22226 - - 1.175e-212 667.0
PYH3_k127_16160_2 transposase activity - - - 0.0000000000000001204 79.0
PYH3_k127_16160_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.000000000005178 67.0
PYH3_k127_1624716_0 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002122 469.0
PYH3_k127_1624716_1 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 335.0
PYH3_k127_1624716_2 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006765 282.0
PYH3_k127_1641509_0 Fe-S oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009569 620.0
PYH3_k127_1641509_1 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007032 304.0
PYH3_k127_164855_0 PFAM sigma-54 factor interaction domain-containing protein K02584 - - 7.506e-225 707.0
PYH3_k127_164855_1 ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 397.0
PYH3_k127_164855_2 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000002559 209.0
PYH3_k127_1650852_0 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001397 296.0
PYH3_k127_1653618_0 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000001563 151.0
PYH3_k127_1653618_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000006002 109.0
PYH3_k127_1662763_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1174.0
PYH3_k127_1662763_1 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001925 302.0
PYH3_k127_1679137_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 3.035e-217 690.0
PYH3_k127_1679137_1 type II secretion system K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 534.0
PYH3_k127_1679137_2 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000027 129.0
PYH3_k127_1686354_0 Tyrosine phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000004202 204.0
PYH3_k127_1686354_1 Pfam Polyketide cyclase dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000008104 188.0
PYH3_k127_1686354_2 Protein of unknown function (DUF3999) - - - 0.0000000000000000008305 100.0
PYH3_k127_1686354_3 Lipocalin-like domain K03098 - - 0.00000000000003694 74.0
PYH3_k127_1695293_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 7.09e-283 877.0
PYH3_k127_1695293_1 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007219 333.0
PYH3_k127_1695293_2 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000000001103 160.0
PYH3_k127_1695293_3 Lipopolysaccharide-assembly, LptC-related - - - 0.00000000005406 69.0
PYH3_k127_1704022_0 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000008763 213.0
PYH3_k127_1704022_1 phosphorelay signal transduction system - - - 0.000000000001323 72.0
PYH3_k127_1704022_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000003341 56.0
PYH3_k127_1710089_0 acetyl-CoA K18122,K18288 - - 6.177e-247 778.0
PYH3_k127_1710089_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003575 334.0
PYH3_k127_1710089_2 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 235.0
PYH3_k127_1710089_3 molybdopterin-guanine dinucleotide biosynthesis protein K03753,K13818 - 2.7.7.77 0.000000000000000001469 85.0
PYH3_k127_1746032_0 PHP domain protein K07053 - 3.1.3.97 5.503e-206 653.0
PYH3_k127_1746032_1 ABC transporter K06020 - 3.6.3.25 0.0000000000002244 70.0
PYH3_k127_1765974_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549,K22363 - 2.1.1.14,4.4.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 421.0
PYH3_k127_1765974_1 PAS sensor protein - - - 0.000000000000000000000000000000000000000000000000000703 188.0
PYH3_k127_1765974_2 PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.000000000000000000000000000000000000000001451 159.0
PYH3_k127_1765974_3 - - - - 0.0000000000000000001818 95.0
PYH3_k127_1765974_4 - - - - 0.000000005482 62.0
PYH3_k127_1765974_5 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000004304 54.0
PYH3_k127_1786371_0 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003738 329.0
PYH3_k127_1786371_1 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008321 278.0
PYH3_k127_1786371_2 - - - - 0.000000000000000000006871 98.0
PYH3_k127_1789003_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.82e-231 720.0
PYH3_k127_1789003_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 545.0
PYH3_k127_1789003_10 Binds the 23S rRNA K02909 - - 0.000000000000000000000000002936 113.0
PYH3_k127_1789003_11 peptidase S8 and S53, subtilisin, kexin, sedolisin K14645 - - 0.00000000003768 68.0
PYH3_k127_1789003_2 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 465.0
PYH3_k127_1789003_3 Protein of unknown function (DUF1385) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 324.0
PYH3_k127_1789003_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000315 263.0
PYH3_k127_1789003_5 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0032259,GO:0036009,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000000000000001437 258.0
PYH3_k127_1789003_6 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.00000000000000000000000000000000000000000000000000000004156 205.0
PYH3_k127_1789003_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000003378 193.0
PYH3_k127_1789003_8 Belongs to the peptidase S8 family K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000005637 196.0
PYH3_k127_1789003_9 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000005196 182.0
PYH3_k127_180872_0 PDZ domain (Also known as DHR or GLGF) K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 479.0
PYH3_k127_180872_1 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000009467 239.0
PYH3_k127_180872_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000000000000000000003013 192.0
PYH3_k127_180872_3 PFAM peptidase K21471 - - 0.000000000000000000000000000000000000000005155 174.0
PYH3_k127_1812973_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 3.486e-200 635.0
PYH3_k127_1812973_1 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 451.0
PYH3_k127_1812973_2 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 326.0
PYH3_k127_1812973_3 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006871 263.0
PYH3_k127_1812973_4 Membrane - - - 0.0000000000000000000000000000004797 131.0
PYH3_k127_1819402_0 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 313.0
PYH3_k127_1819402_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000005418 183.0
PYH3_k127_1820504_0 Heat shock 70 kDa protein K04043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 558.0
PYH3_k127_1820504_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 332.0
PYH3_k127_1820504_2 Periplasmic binding protein K07121 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007626 301.0
PYH3_k127_1820504_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000002694 110.0
PYH3_k127_1824669_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469,K02621 GO:0000819,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006265,GO:0006276,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007062,GO:0008150,GO:0008152,GO:0009330,GO:0009987,GO:0016020,GO:0016043,GO:0019897,GO:0019898,GO:0022402,GO:0030541,GO:0032991,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046483,GO:0051276,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:0098813,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001013 365.0
PYH3_k127_1824669_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002265 301.0
PYH3_k127_1838468_0 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 558.0
PYH3_k127_1838468_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 382.0
PYH3_k127_1838468_2 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000449 327.0
PYH3_k127_1838468_3 ligase activity, forming nitrogen-metal bonds K02230 - 6.6.1.2 0.000000000000000000000000000000000003266 145.0
PYH3_k127_186434_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 534.0
PYH3_k127_186434_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 521.0
PYH3_k127_186434_2 HlyD family secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 448.0
PYH3_k127_186434_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004731 432.0
PYH3_k127_186434_4 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 325.0
PYH3_k127_186434_5 - - - - 0.0000000000000000000000000000000000000000000000001492 184.0
PYH3_k127_186434_6 - - - - 0.00000000000000000000000000000000005569 136.0
PYH3_k127_186434_7 PFAM Cyclic nucleotide-binding K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000001177 61.0
PYH3_k127_1871076_0 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 502.0
PYH3_k127_1871076_1 transcriptional regulatory protein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 326.0
PYH3_k127_1871076_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000003084 196.0
PYH3_k127_1871076_3 Crossover junction endodeoxyribonuclease RuvC K01159 GO:0000725,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008821,GO:0009058,GO:0009059,GO:0009987,GO:0016787,GO:0016788,GO:0016889,GO:0016894,GO:0031297,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0045005,GO:0046483,GO:0048476,GO:0050896,GO:0051716,GO:0071704,GO:0071932,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901576 3.1.22.4 0.000000000000000000000000000000000000000000000001741 179.0
PYH3_k127_1871076_4 - - - - 0.0000001886 55.0
PYH3_k127_1918015_0 PFAM Acyl-CoA dehydrogenase K09456 - - 5.492e-263 823.0
PYH3_k127_1918015_1 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000055 617.0
PYH3_k127_1918015_2 YsiA-like protein, C-terminal region K13770 - - 0.000000000000000000000000000000000000000000000002388 177.0
PYH3_k127_192904_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001441 410.0
PYH3_k127_192904_1 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000000000000000003184 197.0
PYH3_k127_192904_2 Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000001646 126.0
PYH3_k127_1998311_0 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006126 316.0
PYH3_k127_1998311_1 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000000000000000000000000000000772 226.0
PYH3_k127_1998311_2 Zn-dependent hydrolases of the beta-lactamase fold - - - 0.0000000000000000000000000000000000000215 156.0
PYH3_k127_19992_0 PFAM asparagine synthase K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003086 261.0
PYH3_k127_19992_1 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000005383 235.0
PYH3_k127_19992_2 Thioesterase K01075,K07107 - 3.1.2.23 0.000000000000000000000000000000000000000000000888 169.0
PYH3_k127_2015430_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001161 449.0
PYH3_k127_2015430_1 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 398.0
PYH3_k127_2015430_2 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000007783 78.0
PYH3_k127_2015449_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 412.0
PYH3_k127_2015449_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 379.0
PYH3_k127_2028900_0 Required for chromosome condensation and partitioning K03529 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 445.0
PYH3_k127_2028900_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 386.0
PYH3_k127_2028900_2 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000009153 178.0
PYH3_k127_2040847_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 377.0
PYH3_k127_2040847_1 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000001655 111.0
PYH3_k127_206715_0 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009319 366.0
PYH3_k127_206715_1 Membrane - - - 0.000000000000000000000000000000000000000000001066 168.0
PYH3_k127_206715_2 Major facilitator Superfamily K03292 - - 0.000000000000000000000000000000000000000001158 160.0
PYH3_k127_206715_3 Lipid A biosynthesis K02517 - 2.3.1.241 0.0000000000000000000000000000000000001947 153.0
PYH3_k127_206715_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000009103 117.0
PYH3_k127_206715_5 Domain of unknown function (DUF202) K00389 - - 0.000000000000000000009675 93.0
PYH3_k127_2118929_0 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008981 271.0
PYH3_k127_2118929_1 transposase activity - - - 0.0000000000000000000000000000000000000000006744 160.0
PYH3_k127_2118929_2 Phage integrase family K03733 - - 0.000000000000000000000003485 106.0
PYH3_k127_2118929_4 diguanylate cyclase - - - 0.00000003037 61.0
PYH3_k127_2118929_5 - - - - 0.00000003872 62.0
PYH3_k127_2147409_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000006438 235.0
PYH3_k127_2147409_1 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000001182 135.0
PYH3_k127_2147409_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000009433 138.0
PYH3_k127_2147409_3 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000001004 109.0
PYH3_k127_2147409_4 Haemolytic - - - 0.00000000000000000004055 95.0
PYH3_k127_2147409_5 Domain of unknown function (DUF3786) - - - 0.0000000000001472 72.0
PYH3_k127_215217_0 SPTR N-acetylneuraminic acid synthase, N-terminal domain protein K01654 - 2.5.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005459 500.0
PYH3_k127_215217_1 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270,K21749 - 2.7.7.43,2.7.7.92,3.1.3.45 0.00000000000000000000000000000000000000000001519 166.0
PYH3_k127_215217_2 Dehydrogenase - - - 0.000000000000000000002493 99.0
PYH3_k127_215217_3 deoxyhypusine monooxygenase activity - - - 0.00000000000000000951 96.0
PYH3_k127_2158865_0 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000151 280.0
PYH3_k127_2158865_1 PFAM Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000009613 165.0
PYH3_k127_2158865_2 Amidohydrolase family K20810 - 3.5.4.40 0.0000000000000000000000000000000000000003158 154.0
PYH3_k127_2158865_3 Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11783 GO:0003674,GO:0003824,GO:0006732,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009233,GO:0009234,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0051186,GO:0051188,GO:0071704,GO:1901576,GO:1901661,GO:1901663 3.2.2.26 0.0000000000004512 78.0
PYH3_k127_216920_0 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 1.467e-198 626.0
PYH3_k127_216920_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000003099 80.0
PYH3_k127_2193375_0 Belongs to the peptidase M48B family K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 388.0
PYH3_k127_2193375_1 PFAM permease K07089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 339.0
PYH3_k127_2193375_2 Hsp20/alpha crystallin family K13993 - - 0.00000000000000000009447 96.0
PYH3_k127_220568_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007459 576.0
PYH3_k127_220568_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 367.0
PYH3_k127_220568_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000005683 237.0
PYH3_k127_220568_4 DNA-templated transcription, initiation K03088 - - 0.00000000002342 68.0
PYH3_k127_2206500_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 2.863e-206 651.0
PYH3_k127_2206500_1 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000618 297.0
PYH3_k127_2206500_2 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000102 265.0
PYH3_k127_2206500_3 DNA polymerase III, delta' K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000002495 214.0
PYH3_k127_2206500_4 Kdo2-lipid A biosynthetic process K02517 - 2.3.1.241 0.0000000000000000000000000000000002691 140.0
PYH3_k127_2206500_5 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000004421 131.0
PYH3_k127_2206500_6 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000001566 128.0
PYH3_k127_2206500_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.00003657 46.0
PYH3_k127_2206500_8 PFAM AMP-dependent synthetase and ligase K00666 - - 0.0004981 44.0
PYH3_k127_2213785_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000005239 195.0
PYH3_k127_2213785_1 nucleotidyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000002051 194.0
PYH3_k127_2213785_2 Beta-propeller domains of methanol dehydrogenase type K06872 - - 0.0000000000000000000000000000000000000000000003631 173.0
PYH3_k127_2214788_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 508.0
PYH3_k127_2214788_1 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000003374 153.0
PYH3_k127_2225747_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.301e-247 772.0
PYH3_k127_2225747_1 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria - - - 0.0000000000002219 75.0
PYH3_k127_2225747_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.000000000008008 68.0
PYH3_k127_2235616_0 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000006033 246.0
PYH3_k127_2235616_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000001529 229.0
PYH3_k127_2235616_2 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000001634 194.0
PYH3_k127_2251414_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 375.0
PYH3_k127_2251414_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001229 206.0
PYH3_k127_2251414_2 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000009865 194.0
PYH3_k127_2286282_0 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 581.0
PYH3_k127_2286282_1 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 471.0
PYH3_k127_2286282_2 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004056 274.0
PYH3_k127_2286282_3 ADP-ribosylglycohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002835 271.0
PYH3_k127_2317504_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 567.0
PYH3_k127_2317504_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 469.0
PYH3_k127_2317504_2 PFAM PfkB K00856 - 2.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 288.0
PYH3_k127_2317504_3 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.00000000000000000000000387 105.0
PYH3_k127_2331524_0 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 354.0
PYH3_k127_2331524_1 KH domain K06960 - - 0.0000000000000000002912 89.0
PYH3_k127_2331524_2 TIGRFAM MJ0042 family finger-like protein - - - 0.00000000000008668 81.0
PYH3_k127_2331524_3 Putative zinc- or iron-chelating domain - - - 0.00000000002303 74.0
PYH3_k127_2333303_0 cysteine-tRNA ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 457.0
PYH3_k127_2333303_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001195 289.0
PYH3_k127_2333303_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000191 259.0
PYH3_k127_2333303_3 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000002207 249.0
PYH3_k127_2333303_4 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000001097 177.0
PYH3_k127_2383_0 Protein of unknown function (DUF933) K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 306.0
PYH3_k127_2383_1 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004984 289.0
PYH3_k127_2383_2 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
PYH3_k127_2383_3 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001372 245.0
PYH3_k127_2383_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000009437 125.0
PYH3_k127_2383_5 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily - - - 0.00000000000000000004402 90.0
PYH3_k127_2383_6 Tetratricopeptide repeat - - - 0.0000002875 54.0
PYH3_k127_2383_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000002927 57.0
PYH3_k127_2383_8 Putative zinc- or iron-chelating domain K06940 - - 0.0002532 48.0
PYH3_k127_24013_0 PDZ domain (Also known as DHR or GLGF) K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005841 590.0
PYH3_k127_24013_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000000000003246 123.0
PYH3_k127_24013_2 Lipid A Biosynthesis N-terminal domain - - - 0.0000000000000005615 80.0
PYH3_k127_24013_3 Glycosyl transferase family 2 K00721 - 2.4.1.83 0.00000000005801 67.0
PYH3_k127_2457374_0 MiaB-like tRNA modifying enzyme K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000003247 233.0
PYH3_k127_2457724_0 TIGRFAM TIGR00300 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 401.0
PYH3_k127_2457724_1 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004613 286.0
PYH3_k127_2457724_2 protein conserved in bacteria (DUF2179) - - - 0.00000000000000000000000000001736 119.0
PYH3_k127_2474007_0 Belongs to the arginase family K01476,K01480 - 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 309.0
PYH3_k127_2474007_1 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.00000000000000000000000000000000000000000000000000000000002104 209.0
PYH3_k127_2474007_2 CBS domain containing protein K06189 - - 0.000000000000009548 79.0
PYH3_k127_2478441_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008515 590.0
PYH3_k127_2478441_1 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000003319 201.0
PYH3_k127_2478441_2 Putative zinc- or iron-chelating domain - - - 0.00000000000000000000000000000000000005372 152.0
PYH3_k127_2478441_3 Response regulator receiver - - - 0.00000001942 56.0
PYH3_k127_2484414_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 454.0
PYH3_k127_2484414_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 419.0
PYH3_k127_2484414_2 Protein of unknown function DUF116 K09729 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000266 317.0
PYH3_k127_2484414_3 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 289.0
PYH3_k127_2484414_4 PASTA K12132 - 2.7.11.1 0.000000000000000000000000000000000000001423 163.0
PYH3_k127_2486776_0 PFAM magnesium chelatase ChlI subunit K07391 - - 6.611e-216 681.0
PYH3_k127_2486776_1 PFAM cytochrome c biogenesis protein transmembrane region K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004504 342.0
PYH3_k127_2486776_2 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000005918 214.0
PYH3_k127_2486776_3 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 GO:0002682,GO:0002683,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009605,GO:0009607,GO:0009987,GO:0016043,GO:0016829,GO:0016849,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0022607,GO:0031347,GO:0031348,GO:0034214,GO:0035821,GO:0040007,GO:0042802,GO:0043170,GO:0043207,GO:0043545,GO:0043933,GO:0044003,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046483,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051186,GO:0051188,GO:0051189,GO:0051259,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0061799,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:0075136,GO:0080134,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000008982 213.0
PYH3_k127_2486776_4 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000001591 214.0
PYH3_k127_2486776_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000000000001377 213.0
PYH3_k127_2486776_6 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000345 175.0
PYH3_k127_2486776_7 - - - - 0.0000000000000000009811 90.0
PYH3_k127_2486776_8 PFAM Histone deacetylase - - - 0.00000000000000000408 88.0
PYH3_k127_2495631_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.228e-307 962.0
PYH3_k127_2495631_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 1.033e-304 955.0
PYH3_k127_2495631_2 NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 402.0
PYH3_k127_2495631_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 351.0
PYH3_k127_2495631_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006172,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009133,GO:0009135,GO:0009136,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009179,GO:0009180,GO:0009185,GO:0009188,GO:0009259,GO:0009260,GO:0009987,GO:0016020,GO:0016311,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046031,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090304,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990837 - 0.0000000000000000000000000729 115.0
PYH3_k127_2495994_0 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 454.0
PYH3_k127_2495994_1 Amidohydrolase family K01305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 383.0
PYH3_k127_2495994_2 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000007481 224.0
PYH3_k127_2495994_3 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000003935 82.0
PYH3_k127_2498404_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 3.368e-280 878.0
PYH3_k127_2498404_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000004171 253.0
PYH3_k127_2498404_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000005644 132.0
PYH3_k127_2518576_0 Histidine ammonia-lyase K01745 - 4.3.1.3 5.506e-243 758.0
PYH3_k127_2518576_1 Alpha/beta hydrolase family K07020 - - 0.000000000000000000000000000000000000000000008661 167.0
PYH3_k127_2518576_2 SMART Tetratricopeptide domain protein - - - 0.000005541 59.0
PYH3_k127_2518576_3 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00005126 56.0
PYH3_k127_2519161_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002222 368.0
PYH3_k127_2519161_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000005091 147.0
PYH3_k127_2519161_2 FKBP-type peptidyl-prolyl cis-trans isomerase K03775 - 5.2.1.8 0.00000000000000000000000000000000006799 145.0
PYH3_k127_2519161_3 - - - - 0.00000000000000001333 89.0
PYH3_k127_2519161_4 DNA-binding transcriptional activator of the SARP family - - - 0.0000000000003805 79.0
PYH3_k127_2519161_5 - - - - 0.000004207 49.0
PYH3_k127_2522557_0 PBP superfamily domain K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 388.0
PYH3_k127_2522557_1 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000001835 220.0
PYH3_k127_2527337_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 4.83e-216 692.0
PYH3_k127_2527337_1 Mur ligase, middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 406.0
PYH3_k127_2535997_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 524.0
PYH3_k127_2535997_1 Permease YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009566 252.0
PYH3_k127_2535997_2 permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000005476 229.0
PYH3_k127_2547309_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 361.0
PYH3_k127_2547309_1 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 308.0
PYH3_k127_2547309_2 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K01611 - 4.1.1.50 0.0000000000000000000000000000000000000002285 156.0
PYH3_k127_2547309_3 Bacterial protein of unknown function (YtfJ_HI0045) K07109 - - 0.0000000000000000000000003485 112.0
PYH3_k127_2553838_0 PFAM Glycosyl transferase, group 1 K13057 - 2.4.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 522.0
PYH3_k127_2553838_1 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000004316 173.0
PYH3_k127_2558114_0 Histidine kinase K02480 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003033 280.0
PYH3_k127_2558114_1 3D domain protein - - - 0.0000000000000000000000000000000001043 138.0
PYH3_k127_2561596_0 NADP-dependent oxidoreductase K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 418.0
PYH3_k127_2561596_1 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 338.0
PYH3_k127_2561596_2 Oxidoreductase molybdopterin binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007098 302.0
PYH3_k127_2561596_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000007635 139.0
PYH3_k127_2561596_4 - - - - 0.00000000000000000000000000000000074 136.0
PYH3_k127_2561596_5 Peptidase_C39 like family - - - 0.0000000000000000000000004132 112.0
PYH3_k127_2561596_6 PFAM Cyclic nucleotide-binding K10914 - - 0.0000000001032 70.0
PYH3_k127_2561596_7 Uncharacterised ArCR, COG2043 - - - 0.0005502 47.0
PYH3_k127_2563741_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370 - 1.7.5.1 0.0 1961.0
PYH3_k127_2563741_1 Catalyzes the reduction of hydroxylamine to form NH(3) and H(2)O K05601 - 1.7.99.1 3.358e-298 921.0
PYH3_k127_2563741_10 NUDIX domain - - - 0.000000000000000000000000000000000000000000000000000000000001089 215.0
PYH3_k127_2563741_11 PFAM Cupin 2 conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000006941 159.0
PYH3_k127_2563741_12 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00000000000000000000000000000000003801 139.0
PYH3_k127_2563741_13 HlyD membrane-fusion protein of T1SS K03543 - - 0.00000000000000000000271 98.0
PYH3_k127_2563741_14 - - - - 0.000000000000006163 78.0
PYH3_k127_2563741_15 - - - - 0.0000000002631 63.0
PYH3_k127_2563741_2 4Fe-4S dicluster domain K00371 - 1.7.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 601.0
PYH3_k127_2563741_3 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 619.0
PYH3_k127_2563741_4 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 492.0
PYH3_k127_2563741_5 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007637 435.0
PYH3_k127_2563741_6 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 397.0
PYH3_k127_2563741_7 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 339.0
PYH3_k127_2563741_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000698 331.0
PYH3_k127_2563741_9 nitric oxide reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000001445 220.0
PYH3_k127_2566070_0 diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 390.0
PYH3_k127_2566070_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 364.0
PYH3_k127_2566070_2 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005743 288.0
PYH3_k127_2566070_3 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004565 275.0
PYH3_k127_2566070_4 Protein involved in outer membrane biogenesis - - - 0.0000000000000000000000000004954 122.0
PYH3_k127_2566070_5 Glutathione S-transferase, N-terminal domain - - - 0.0000000000000002182 83.0
PYH3_k127_2566070_6 including yeast histone deacetylase and acetoin utilization protein - - - 0.00000000563 60.0
PYH3_k127_2571492_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 2.702e-222 700.0
PYH3_k127_2571492_1 PFAM class II aldolase adducin family protein K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 454.0
PYH3_k127_2571492_2 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 359.0
PYH3_k127_2571492_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000003129 203.0
PYH3_k127_2571492_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000001385 89.0
PYH3_k127_2571492_5 positive regulation of growth rate - - - 0.0008754 49.0
PYH3_k127_2587406_0 Beta-lactamase superfamily domain K06167 - 3.1.4.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 356.0
PYH3_k127_2587406_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000001509 205.0
PYH3_k127_2587406_2 Cytidylate kinase-like family K00760 - 2.4.2.8 0.000000000000000000000000000000000000000535 158.0
PYH3_k127_2587406_3 Serine aminopeptidase, S33 K06889,K07397 - - 0.000000000000000000000000000000000000005504 154.0
PYH3_k127_2587406_4 - - - - 0.0000000000000000000000000007974 121.0
PYH3_k127_2588195_0 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000818 520.0
PYH3_k127_2588195_1 CGGC - - - 0.000000000000000000000000000000000000000000000000000000000005447 211.0
PYH3_k127_2588195_2 - - - - 0.00000000000000000000000000004852 119.0
PYH3_k127_2588195_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000001543 76.0
PYH3_k127_2600723_0 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001165 285.0
PYH3_k127_2600723_1 Penicillin-Binding Protein C-terminus Family K05367 - 2.4.1.129 0.000000000000000000000000000000000000179 151.0
PYH3_k127_2619470_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.207e-244 766.0
PYH3_k127_2619470_1 PFAM Pyruvate carboxyltransferase - - - 2.973e-205 644.0
PYH3_k127_262749_0 pfam abc-1 K03688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004724 584.0
PYH3_k127_262749_1 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 400.0
PYH3_k127_262749_10 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.0000000000000000753 83.0
PYH3_k127_262749_11 - - - - 0.000000000004099 75.0
PYH3_k127_262749_13 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306 - 1.8.5.3 0.0000001087 60.0
PYH3_k127_262749_2 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007794 346.0
PYH3_k127_262749_3 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002506 348.0
PYH3_k127_262749_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 332.0
PYH3_k127_262749_5 Psort location Cytoplasmic, score K09707 - - 0.00000000000000000000000000000000000000009141 154.0
PYH3_k127_262749_6 amino acid - - - 0.000000000000000000000000000000006037 143.0
PYH3_k127_262749_7 DoxX - - - 0.0000000000000000000000000000003028 128.0
PYH3_k127_262749_8 Rhodanese Homology Domain - - - 0.000000000000000000000002883 115.0
PYH3_k127_262749_9 - - - - 0.000000000000000000001839 101.0
PYH3_k127_2648559_0 PFAM Glycosyltransferase 28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009923 498.0
PYH3_k127_2648559_1 DEAD DEAH box helicase K06877 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009269 493.0
PYH3_k127_2648559_2 Protein of unknown function (DUF1343) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001289 448.0
PYH3_k127_2648559_3 Forkhead associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001537 238.0
PYH3_k127_2648559_4 Major Facilitator Superfamily K02445 - - 0.000000000000000000000000000002491 125.0
PYH3_k127_2648559_5 Fibronectin type III domain protein - - - 0.000001878 59.0
PYH3_k127_2648559_6 PilZ domain - - - 0.00001253 53.0
PYH3_k127_2648559_7 - - - - 0.0002521 51.0
PYH3_k127_2650203_0 PFAM Protein kinase domain K05385,K12132,K13590 - 2.7.11.1,2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005749 569.0
PYH3_k127_2650203_1 Putative zinc- or iron-chelating domain - - - 0.0000001901 54.0
PYH3_k127_2659210_0 Dynamin family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 490.0
PYH3_k127_2659210_1 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0003674,GO:0003824,GO:0004766,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0010487,GO:0016740,GO:0016765,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0050314,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000007567 250.0
PYH3_k127_2659210_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000001182 190.0
PYH3_k127_2659210_3 Acetyltransferase K03789 - 2.3.1.128 0.000000000000000000104 94.0
PYH3_k127_267229_0 4Fe-4S binding domain - - - 9.652e-252 790.0
PYH3_k127_268362_0 PFAM periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005582 305.0
PYH3_k127_268362_1 TonB-dependent Receptor Plug Domain - - - 0.0000000000000000000000000002709 127.0
PYH3_k127_2696058_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005431 404.0
PYH3_k127_2716230_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 563.0
PYH3_k127_2716230_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000004625 66.0
PYH3_k127_2733610_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1487.0
PYH3_k127_2733610_1 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002928 357.0
PYH3_k127_2733610_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 316.0
PYH3_k127_2733610_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 260.0
PYH3_k127_2733610_4 PFAM nuclease (SNase - - - 0.00000000000001752 76.0
PYH3_k127_2733610_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.000000002025 60.0
PYH3_k127_2733610_6 Histidine kinase - - - 0.0000000387 59.0
PYH3_k127_2766429_0 Endoribonuclease that initiates mRNA decay K18682 - - 2.624e-206 653.0
PYH3_k127_2795941_0 aminopeptidase N - - - 0.00000000000000000000000000000000000000000000000000002909 196.0
PYH3_k127_2795941_1 UbiA prenyltransferase family - - - 0.000000000000000000000000000000000000004076 149.0
PYH3_k127_2795941_2 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000006985 139.0
PYH3_k127_2795941_3 PFAM Radical SAM domain protein - - - 0.00000000000000000000001114 104.0
PYH3_k127_2808171_0 Histone deacetylase domain K04768 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 375.0
PYH3_k127_2808171_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004227 347.0
PYH3_k127_2808171_2 AIR synthase related protein, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003106 283.0
PYH3_k127_2808171_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009581 245.0
PYH3_k127_2808171_4 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000001101 228.0
PYH3_k127_2808171_5 FHA domain - - - 0.0000000000009798 74.0
PYH3_k127_2808171_6 Forkhead associated domain - - - 0.00000000005485 70.0
PYH3_k127_2808171_7 PFAM regulatory protein AsnC Lrp family - - - 0.0000000004153 63.0
PYH3_k127_2826877_0 CheY-like receiver, AAA-type ATPase, and DNA-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 537.0
PYH3_k127_2826877_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000006921 206.0
PYH3_k127_2826877_2 lysine 2,3-aminomutase - - - 0.00000000000000000000000000000000004486 139.0
PYH3_k127_2826877_3 - - - - 0.000393 48.0
PYH3_k127_2842179_0 PFAM glycosyl transferase family 9 K02841 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 341.0
PYH3_k127_2842179_1 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.00000000000000000000000000000000001503 138.0
PYH3_k127_2842179_2 Belongs to the UPF0434 family K09791 - - 0.000000000000000000000001768 103.0
PYH3_k127_2842179_3 glycosyl transferase group 1 - - - 0.0000000000003643 71.0
PYH3_k127_2843333_0 Belongs to the RtcB family K14415 - 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 569.0
PYH3_k127_2843333_1 Belongs to the RtcB family K14415 - 6.5.1.3 0.0000000000000000000000000000000000000003317 151.0
PYH3_k127_2843333_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000343 154.0
PYH3_k127_2843333_3 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000006901 119.0
PYH3_k127_2843333_4 Rhodanese Homology Domain - - - 0.0000000000000000000004294 99.0
PYH3_k127_2847345_0 COGs COG5000 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008238 294.0
PYH3_k127_2847345_1 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006503 275.0
PYH3_k127_2847345_2 - - - - 0.0000000000000000000000000000005432 127.0
PYH3_k127_2847345_3 acetyltransferase K01246 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008080,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0044424,GO:0044464 3.2.2.20 0.0000000000000000000281 98.0
PYH3_k127_2852268_0 thiamine pyrophosphate protein TPP binding domain protein - - - 0.000000000000000000000000000000000000001318 151.0
PYH3_k127_2852268_1 Transcriptional regulator - - - 0.0000000000000000000000000000006364 128.0
PYH3_k127_2852268_2 Belongs to the glycosyl hydrolase 57 family - - - 0.000007015 52.0
PYH3_k127_2874227_0 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001511 245.0
PYH3_k127_2874227_1 heat shock protein binding K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000001321 222.0
PYH3_k127_2874227_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate K03701 - - 0.0000000000001549 70.0
PYH3_k127_2877521_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006165 297.0
PYH3_k127_2877521_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000249 192.0
PYH3_k127_2877521_2 PFAM Lytic K08309 - - 0.0000000000000000000000000000000000000000000000001822 184.0
PYH3_k127_2877521_3 monooxygenase activity - - - 0.0000000001055 65.0
PYH3_k127_2877521_4 - - - - 0.000005206 49.0
PYH3_k127_287883_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 509.0
PYH3_k127_2885087_0 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 446.0
PYH3_k127_2885087_1 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009841 280.0
PYH3_k127_2885087_2 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000007619 223.0
PYH3_k127_2888270_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02022,K16922,K20345 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 444.0
PYH3_k127_2892130_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005498 596.0
PYH3_k127_2892130_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004286 375.0
PYH3_k127_2892130_2 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000000009512 139.0
PYH3_k127_2899009_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 320.0
PYH3_k127_2899009_1 glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001851 291.0
PYH3_k127_2899009_2 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000009487 193.0
PYH3_k127_2899009_3 enoyl-[acyl-carrier-protein] reductase (NADH) activity - - - 0.000000000000000000000000000000000000009512 152.0
PYH3_k127_2899009_4 Nucleotidyltransferase domain - - - 0.0000000000000000000000000000000000549 138.0
PYH3_k127_2899009_5 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.000000000000000000000000000002083 121.0
PYH3_k127_2899009_6 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000000156 115.0
PYH3_k127_2899009_7 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000000000000000001581 111.0
PYH3_k127_2899009_8 nucleotidyltransferase activity - - - 0.00000000000000000003934 94.0
PYH3_k127_2901286_0 PFAM Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009204 455.0
PYH3_k127_2901286_1 Belongs to the UPF0758 family K03630 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001763 275.0
PYH3_k127_2901286_2 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000001198 201.0
PYH3_k127_2901286_3 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000001674 168.0
PYH3_k127_2901286_4 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000189 70.0
PYH3_k127_2901286_5 PilZ domain - - - 0.0008496 48.0
PYH3_k127_2901467_0 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 509.0
PYH3_k127_2901467_1 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000002659 178.0
PYH3_k127_2901467_2 AIR carboxylase K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000139 166.0
PYH3_k127_2901467_3 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.00000000000000000000000000000000000000000004488 185.0
PYH3_k127_2904788_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378,K13380 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 553.0
PYH3_k127_2904788_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 454.0
PYH3_k127_2904788_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K05580 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000003582 202.0
PYH3_k127_2904788_3 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000001246 183.0
PYH3_k127_2904788_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000009827 134.0
PYH3_k127_2904788_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000000000002161 120.0
PYH3_k127_2904788_6 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000004981 113.0
PYH3_k127_2921018_0 Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB K16147 - 2.4.99.16 1.264e-268 842.0
PYH3_k127_2921018_1 glycogen (starch) synthase activity K16148 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0006073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0071704,GO:1901576 2.4.1.342 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007985 523.0
PYH3_k127_2921018_2 Bacterial extracellular solute-binding protein K02027,K10236 - - 0.000000000000000000000000000000000000000000000000004922 191.0
PYH3_k127_2928433_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08357 - - 1.381e-214 691.0
PYH3_k127_2928433_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 551.0
PYH3_k127_2928433_2 ABC transporter K16786,K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 403.0
PYH3_k127_2928433_3 iron-sulfur binding K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 372.0
PYH3_k127_2928433_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005064 299.0
PYH3_k127_2928433_5 ThiW protein K16786,K16787 - - 0.0000000000000000000000000000000000000000004131 165.0
PYH3_k127_2928433_6 Cobalt transport protein K16785 - - 0.000000000000000000000000000219 125.0
PYH3_k127_2938591_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 480.0
PYH3_k127_2938591_1 PFAM Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 402.0
PYH3_k127_2938591_2 - - - - 0.000000000000000000001185 100.0
PYH3_k127_2971923_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 296.0
PYH3_k127_2971923_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000001738 86.0
PYH3_k127_2971923_2 PFAM GAF domain - - - 0.000000000002801 68.0
PYH3_k127_297318_0 pfam abc K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 407.0
PYH3_k127_297318_1 HlyD family secretion protein K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003544 331.0
PYH3_k127_297318_2 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 325.0
PYH3_k127_2980656_0 ABC transporter K06020 - 3.6.3.25 1.067e-305 943.0
PYH3_k127_2986932_0 Cytochrome b/b6/petB K00412 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 477.0
PYH3_k127_2986932_1 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 444.0
PYH3_k127_2986932_2 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 404.0
PYH3_k127_2986932_3 Rieske [2Fe-2S] domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008589 228.0
PYH3_k127_2986932_4 - - - - 0.000000000000000000001826 98.0
PYH3_k127_2986932_5 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000001115 62.0
PYH3_k127_298757_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 554.0
PYH3_k127_298757_1 TIGRFAM Ammonium transporter K03320 - - 0.00000000000000000000000000000000000000000000000000000000000704 209.0
PYH3_k127_298757_2 Nitrogen regulatory protein P-II K04751 GO:0003674,GO:0006808,GO:0008150,GO:0030234,GO:0050789,GO:0050790,GO:0065007,GO:0065009,GO:0098772 - 0.00000000000000000000000000000000000000000000001641 172.0
PYH3_k127_2993873_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 438.0
PYH3_k127_2993873_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 435.0
PYH3_k127_2993873_2 PFAM Band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 368.0
PYH3_k127_2993873_3 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000002964 231.0
PYH3_k127_2993873_4 Putative TM nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000000001384 208.0
PYH3_k127_2993873_5 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.000000000000000000000000000005303 125.0
PYH3_k127_2996412_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 6.918e-209 654.0
PYH3_k127_2996412_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000002847 145.0
PYH3_k127_2996412_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.0000000000000002594 81.0
PYH3_k127_3015067_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 479.0
PYH3_k127_3015067_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003248 466.0
PYH3_k127_3015067_2 AAA domain K02450 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005581 404.0
PYH3_k127_3015067_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 313.0
PYH3_k127_3015067_4 Jag_N K06346 - - 0.00000000000000000000000000000000000000000000000000000000000008518 220.0
PYH3_k127_3015067_5 PFAM cytochrome c class III - - - 0.00000000000000000000000002155 110.0
PYH3_k127_3015067_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000008865 102.0
PYH3_k127_3015067_7 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000419 104.0
PYH3_k127_3015067_8 AAA domain K02450 - - 0.00000000000000000001056 104.0
PYH3_k127_3015067_9 Ribosomal protein L34 K02914 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001689 74.0
PYH3_k127_3025581_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 527.0
PYH3_k127_3025581_1 nitrite transmembrane transporter activity K02575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 400.0
PYH3_k127_3025581_2 nitrate reductase, gamma subunit K00374 - 1.7.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009673 287.0
PYH3_k127_3025581_3 TIGRFAM nitrate reductase molybdenum cofactor assembly chaperone K00373 - - 0.000000000000000000000000000003775 126.0
PYH3_k127_3025581_4 Divergent 4Fe-4S mono-cluster K05337 - - 0.000000000000000000001882 101.0
PYH3_k127_3025581_5 Nitrate reductase beta subunit K00371 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008940,GO:0009055,GO:0009061,GO:0009325,GO:0009898,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016661,GO:0019645,GO:0022900,GO:0022904,GO:0031224,GO:0031226,GO:0031235,GO:0032991,GO:0033554,GO:0042126,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0044799,GO:0045333,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204,GO:2001057 1.7.5.1 0.00000000000001689 74.0
PYH3_k127_3025968_0 Pfam SEC-C motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005082 301.0
PYH3_k127_3025968_1 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000005045 239.0
PYH3_k127_3025968_2 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.0000000000000000000000000000000000000000000000000000000000002057 218.0
PYH3_k127_3025968_3 Ogr/Delta-like zinc finger - - - 0.00000000000000000000004719 101.0
PYH3_k127_3055075_0 outer membrane efflux protein K12340 - - 0.0000000000000000000000000000000000000000000000000000215 202.0
PYH3_k127_3055075_1 Phosphomethylpyrimidine kinase K00941,K14153 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000002931 52.0
PYH3_k127_3055342_0 HRDC domain K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005088 266.0
PYH3_k127_3055342_1 Smr domain - - - 0.00000000000000000000000000000000000000000000000000005734 196.0
PYH3_k127_3128238_0 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000007344 244.0
PYH3_k127_3128238_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000001477 216.0
PYH3_k127_3130566_0 Curli production assembly/transport component CsgG - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003408 265.0
PYH3_k127_3130566_1 serine threonine protein kinase K08884 - 2.7.11.1 0.00000000005368 70.0
PYH3_k127_3130566_2 Subtilase family - - - 0.0000000002017 69.0
PYH3_k127_3130566_3 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.0005938 46.0
PYH3_k127_3139785_0 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 379.0
PYH3_k127_3139785_1 Regulatory protein, FmdB family - - - 0.0002689 46.0
PYH3_k127_3140266_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 5.469e-203 644.0
PYH3_k127_3140266_1 His Kinase A (phosphoacceptor) domain K02668 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 407.0
PYH3_k127_3140266_2 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000324 170.0
PYH3_k127_3182934_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 489.0
PYH3_k127_3182934_1 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 381.0
PYH3_k127_3182934_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001447 260.0
PYH3_k127_3182934_4 Bifunctional nuclease K08999 - - 0.00000000000000000000000000000000000000000001252 174.0
PYH3_k127_3182934_5 Protein of unknown function (DUF2905) - - - 0.0000002164 56.0
PYH3_k127_3209516_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1038.0
PYH3_k127_3209516_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 9.907e-305 955.0
PYH3_k127_3209516_10 chemotaxis K03408 - - 0.00000000000000000000000278 108.0
PYH3_k127_3209516_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0000166,GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006275,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901363,GO:1901576,GO:1990837,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004353 482.0
PYH3_k127_3209516_3 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006355 368.0
PYH3_k127_3209516_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000425 349.0
PYH3_k127_3209516_5 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 310.0
PYH3_k127_3209516_6 CheC-like family K03410 - - 0.000000000000000000000000000000000000000000000000000000003111 205.0
PYH3_k127_3209516_7 PFAM Class II aldolase K01628 - 4.1.2.17 0.0000000000000000000000000000000000000000000000000000001103 201.0
PYH3_k127_3209516_8 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000008613 130.0
PYH3_k127_3209516_9 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000008711 113.0
PYH3_k127_3211327_0 Isocitrate lyase K01637 - 4.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 607.0
PYH3_k127_3211327_1 [isocitrate dehydrogenase (NADP+)] phosphatase activity K00906 GO:0000166,GO:0003674,GO:0003824,GO:0004672,GO:0004674,GO:0004721,GO:0004722,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006081,GO:0006082,GO:0006091,GO:0006097,GO:0006099,GO:0006101,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008772,GO:0009060,GO:0009987,GO:0015980,GO:0016208,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0016999,GO:0017076,GO:0017144,GO:0018105,GO:0018193,GO:0018209,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0035639,GO:0036094,GO:0036211,GO:0042578,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044260,GO:0044262,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046487,GO:0050790,GO:0055114,GO:0065007,GO:0065009,GO:0070262,GO:0071704,GO:0072350,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007702 584.0
PYH3_k127_3211327_2 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002533 287.0
PYH3_k127_3211327_3 HD domain - - - 0.0000000000000000000000000000000000000000000000000006109 193.0
PYH3_k127_3211327_4 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000009569 187.0
PYH3_k127_3228013_0 ABC transporter K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002684 299.0
PYH3_k127_3228013_1 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007459 263.0
PYH3_k127_3263960_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007471 442.0
PYH3_k127_3263960_1 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000001536 53.0
PYH3_k127_3287910_0 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000474 249.0
PYH3_k127_3287910_1 - - - - 0.0006574 46.0
PYH3_k127_3343425_0 GMP synthase C terminal domain K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 473.0
PYH3_k127_3343425_1 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000002029 252.0
PYH3_k127_334465_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1259.0
PYH3_k127_334465_1 PFAM Peptidase M16C associated K06972 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 447.0
PYH3_k127_334465_2 4Fe-4S dicluster domain K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006899 319.0
PYH3_k127_334465_3 molybdopterin oxidoreductase Fe4S4 K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000004359 265.0
PYH3_k127_334465_4 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000000000000000006262 158.0
PYH3_k127_334465_5 Redoxin K03386 - 1.11.1.15 0.0000000000000000000000002549 105.0
PYH3_k127_3376010_1 COG2143 Thioredoxin-related protein - - - 0.00000000000000000000006913 106.0
PYH3_k127_3386207_0 PFAM sigma-54 factor interaction domain-containing protein K02481,K07714,K10943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 383.0
PYH3_k127_3386207_1 pilus assembly protein K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 377.0
PYH3_k127_3386207_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004842 271.0
PYH3_k127_3386207_3 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000007734 137.0
PYH3_k127_3386207_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07710 - 2.7.13.3 0.000000000000000000000000000005515 138.0
PYH3_k127_3386207_5 type IV pilus secretin PilQ K02666 - - 0.000000000004304 78.0
PYH3_k127_3386207_6 PFAM Fimbrial assembly family protein K02663 - - 0.0000009415 57.0
PYH3_k127_3386207_7 Pilus assembly protein, PilP K02665 - - 0.00001877 54.0
PYH3_k127_3386207_8 DnaJ molecular chaperone homology domain - GO:0000003,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005783,GO:0005788,GO:0005911,GO:0006950,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009506,GO:0009628,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0012505,GO:0016043,GO:0016049,GO:0016491,GO:0022414,GO:0030054,GO:0030154,GO:0031974,GO:0032501,GO:0032502,GO:0032989,GO:0033554,GO:0034605,GO:0040007,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0044706,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050896,GO:0051704,GO:0051716,GO:0055044,GO:0055114,GO:0060560,GO:0070013,GO:0071840 - 0.00008444 52.0
PYH3_k127_3410786_0 Histone deacetylase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007774 340.0
PYH3_k127_3410786_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003177 285.0
PYH3_k127_3410786_2 Nitroreductase family - - - 0.0000000000000000000000000000000000000000001591 162.0
PYH3_k127_343335_0 oxidoreductase activity, acting on other nitrogenous compounds as donors K01118 GO:0003674,GO:0003824,GO:0006082,GO:0006629,GO:0006631,GO:0008081,GO:0008150,GO:0008152,GO:0008770,GO:0009987,GO:0016787,GO:0016788,GO:0019752,GO:0032787,GO:0042578,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0071704,GO:0140096 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000211 273.0
PYH3_k127_343335_1 cytidyltransferase-related domain K00952 - 2.7.7.1 0.00000000000000000000000000000000000000008581 158.0
PYH3_k127_343335_2 Phosphate-starvation-inducible E - - - 0.0000000000000000000000000000000000519 138.0
PYH3_k127_343335_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K07281,K07291 - 2.7.7.74,2.7.8.34 0.00000000001368 75.0
PYH3_k127_3445455_0 PFAM DAHP synthetase I KDSA K03856,K04516 - 2.5.1.54,5.4.99.5 1.475e-273 854.0
PYH3_k127_3445455_1 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 430.0
PYH3_k127_350172_0 PFAM Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 492.0
PYH3_k127_350172_1 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000007352 203.0
PYH3_k127_3526019_0 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 471.0
PYH3_k127_3526019_1 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 381.0
PYH3_k127_3526019_2 - - - - 0.0000000000000000000000000000000000000000000000000001139 189.0
PYH3_k127_3526019_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000001563 189.0
PYH3_k127_3526019_4 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000003149 177.0
PYH3_k127_3526019_5 PFAM response regulator receiver - - - 0.00000000000000000000000000000000002347 138.0
PYH3_k127_3526019_6 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.000000000000000000008504 94.0
PYH3_k127_3526019_7 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000002977 89.0
PYH3_k127_3526019_8 Protein of unknown function (DUF3106) - - - 0.0000000000000001275 87.0
PYH3_k127_3526019_9 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.00000000000002464 77.0
PYH3_k127_3573761_0 TatD related DNase K03424 GO:0003674,GO:0003824,GO:0004518,GO:0004536,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002502 280.0
PYH3_k127_3573761_1 deoxyhypusine monooxygenase activity - - - 0.000175 53.0
PYH3_k127_3616035_0 PFAM Protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 479.0
PYH3_k127_3616035_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000001924 209.0
PYH3_k127_3616035_2 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000000000002362 156.0
PYH3_k127_3616035_3 transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000002959 100.0
PYH3_k127_3616035_4 Phage integrase family - - - 0.00000000002251 72.0
PYH3_k127_3616035_5 Helix-turn-helix domain - - - 0.00009384 47.0
PYH3_k127_3667257_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 486.0
PYH3_k127_3667257_1 Peptidase M16 domain protein K07263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008103 422.0
PYH3_k127_3667257_2 - - - - 0.0000008977 53.0
PYH3_k127_36724_0 Transglycosylase SLT domain K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 426.0
PYH3_k127_36724_1 RNA recognition motif - - - 0.000000000000000000000002727 105.0
PYH3_k127_36724_2 - - - - 0.000001612 51.0
PYH3_k127_368211_0 Prokaryotic N-terminal methylation motif - - - 0.000000000000002446 84.0
PYH3_k127_368211_1 Neisseria PilC beta-propeller domain K02674 - - 0.000000000003472 76.0
PYH3_k127_368211_2 Prokaryotic N-terminal methylation motif K02671 - - 0.00000000007148 68.0
PYH3_k127_368211_3 PilX N-terminal - - - 0.0004736 51.0
PYH3_k127_3686607_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 336.0
PYH3_k127_3686607_1 PFAM Peptidase family S58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 312.0
PYH3_k127_3686607_2 PFAM metal-dependent phosphohydrolase, HD sub domain K07023 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 276.0
PYH3_k127_3686607_3 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000005482 241.0
PYH3_k127_3686607_4 - - - - 0.00000000000000004951 84.0
PYH3_k127_3686607_5 COG0717 Deoxycytidine deaminase - - - 0.000000002956 64.0
PYH3_k127_3707084_0 TIGRFAM secondary thiamine-phosphate synthase enzyme - - - 0.000000000000000000000000000001501 124.0
PYH3_k127_3707084_2 Cysteine-rich domain - - - 0.000000000000001437 80.0
PYH3_k127_372408_0 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 481.0
PYH3_k127_372408_1 PFAM TonB-dependent Receptor Plug K02014 - - 0.000000000000000000000000000000000000000000000000001737 196.0
PYH3_k127_372408_2 Binding-protein-dependent transport system inner membrane component K02037,K02038 - - 0.00000000000000001425 89.0
PYH3_k127_3727616_0 PFAM Acyl-CoA dehydrogenase - - - 1.545e-198 632.0
PYH3_k127_3735461_0 PFAM response regulator receiver K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 474.0
PYH3_k127_3735461_1 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000000000000000001613 219.0
PYH3_k127_3750400_0 PFAM SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 398.0
PYH3_k127_3750400_1 radical SAM domain protein K03716 - 4.1.99.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 392.0
PYH3_k127_3750400_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000000000000000000005109 99.0
PYH3_k127_3750400_12 Biotin-requiring enzyme - - - 0.0000001009 53.0
PYH3_k127_3750400_2 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000001318 235.0
PYH3_k127_3750400_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000003835 237.0
PYH3_k127_3750400_4 Staphylococcal nuclease homologues - - - 0.000000000000000000000000000000000000000000000000000002362 199.0
PYH3_k127_3750400_5 PFAM Uncharacterised ACR, COG1259 K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000455 192.0
PYH3_k127_3750400_6 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000000002295 153.0
PYH3_k127_3750400_7 Domain of unknown function (DUF374) K09778 - - 0.000000000000000000000000000000000000003118 158.0
PYH3_k127_3750400_8 Cold shock protein domain K03704 - - 0.000000000000000000000000002904 111.0
PYH3_k127_3750400_9 ParB domain protein nuclease K03497 - - 0.00000000000000000000000355 114.0
PYH3_k127_3767187_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 2.818e-203 642.0
PYH3_k127_3767187_1 - - - - 0.000000000000000000000000000000000000000000000000004759 185.0
PYH3_k127_3767187_2 DUF218 domain - - - 0.000000000000000000000000009661 123.0
PYH3_k127_3767607_0 Pyridine nucleotide-disulphide oxidoreductase - - - 2.442e-293 907.0
PYH3_k127_3767607_1 FAD dependent oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 2.434e-208 654.0
PYH3_k127_3767607_10 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000002374 134.0
PYH3_k127_3767607_11 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006275,GO:0008150,GO:0008156,GO:0009889,GO:0009890,GO:0009892,GO:0010556,GO:0010558,GO:0010605,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019219,GO:0019222,GO:0030174,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032297,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0045934,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051302,GO:0051781,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0090329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:2000104,GO:2000112,GO:2000113 - 0.00000000003364 69.0
PYH3_k127_3767607_2 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002161 466.0
PYH3_k127_3767607_3 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 366.0
PYH3_k127_3767607_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000781 334.0
PYH3_k127_3767607_5 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000227 269.0
PYH3_k127_3767607_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000000000000361 246.0
PYH3_k127_3767607_7 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000004692 211.0
PYH3_k127_3767607_8 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000005706 192.0
PYH3_k127_3767607_9 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000638 184.0
PYH3_k127_3777163_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.783e-263 832.0
PYH3_k127_3777163_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000051 278.0
PYH3_k127_3777163_2 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
PYH3_k127_3777163_3 Belongs to the Fur family K03711 - - 0.000000000000000000000000000000000000000000000000000006557 198.0
PYH3_k127_3777163_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000001989 154.0
PYH3_k127_3777163_5 Belongs to the Fur family K03711 - - 0.000000000000000000000003548 104.0
PYH3_k127_3792912_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 556.0
PYH3_k127_3792912_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 366.0
PYH3_k127_3812063_0 glycosyl transferase group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 384.0
PYH3_k127_3812063_1 Sulfotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005136 321.0
PYH3_k127_3812063_2 glycosyl transferase group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007756 262.0
PYH3_k127_3818898_0 PFAM Xylose isomerase domain protein TIM barrel - - - 0.000000000000000000000000000000000000000000000000000001873 202.0
PYH3_k127_3818898_1 Cobinamide kinase cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000000004299 195.0
PYH3_k127_3818898_2 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000002014 193.0
PYH3_k127_3818898_4 protein kinase activity - - - 0.0000000000000000000000000000002692 129.0
PYH3_k127_3822846_0 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 9.668e-318 994.0
PYH3_k127_3822846_1 Domain of Unknown Function (DUF748) - - - 1.141e-199 654.0
PYH3_k127_3822846_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302,K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000007161 243.0
PYH3_k127_3822846_3 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.0000000000000000000000000000000000000000000000000013 186.0
PYH3_k127_3837140_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 2.923e-223 702.0
PYH3_k127_3837140_1 PFAM PhoH family protein K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 420.0
PYH3_k127_3837140_2 metal-dependent phosphohydrolase 7TM intracellular region K07037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008932 413.0
PYH3_k127_3837140_3 Phosphoribosyl-ATP pyrophosphohydrolase K02499,K04765 - 3.6.1.9 0.00000000000000000000000000000000000000000000000000001223 198.0
PYH3_k127_3837140_4 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000002171 196.0
PYH3_k127_3837140_5 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000009475 176.0
PYH3_k127_3837140_6 - - - - 0.0000000000000000000000001569 119.0
PYH3_k127_3837140_7 PFAM Colicin V production protein K03558 - - 0.00000000000001152 81.0
PYH3_k127_3837140_8 heat shock protein binding - - - 0.00000000003085 74.0
PYH3_k127_3847805_0 phosphate transport system permease protein K02038 - - 1.753e-246 772.0
PYH3_k127_3847805_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001392 417.0
PYH3_k127_3847805_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000002771 214.0
PYH3_k127_3847805_3 Prolipoprotein diacylglyceryl transferase - - - 0.0000000255 57.0
PYH3_k127_3852802_0 Belongs to the PEP-utilizing enzyme family K08484 - 2.7.3.9 3.698e-224 718.0
PYH3_k127_3852802_1 - - - - 0.00000000000000000000000000005187 126.0
PYH3_k127_3852802_2 endonuclease III K07457 - - 0.0000000000000002369 81.0
PYH3_k127_3861365_0 ATPase associated with various cellular activities - - - 0.00000000000000000000000000000000000000000000005855 183.0
PYH3_k127_3861365_1 GXGXG motif - - - 0.0001742 51.0
PYH3_k127_3866607_0 Potential Queuosine, Q, salvage protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 311.0
PYH3_k127_3866607_1 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000003661 264.0
PYH3_k127_3866607_2 PFAM ATP-binding region ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000005096 159.0
PYH3_k127_3866607_3 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000002097 102.0
PYH3_k127_3866607_4 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000002917 66.0
PYH3_k127_3874900_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000001129 227.0
PYH3_k127_3874900_1 PFAM Methyl-accepting chemotaxis protein (MCP) K03406 - - 0.0000000000000000000000000000000009384 148.0
PYH3_k127_3878776_0 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002059 274.0
PYH3_k127_3878776_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000001606 201.0
PYH3_k127_3878776_2 oxidoreductase activity - - - 0.00000006296 64.0
PYH3_k127_3889260_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 7.122e-279 869.0
PYH3_k127_3889260_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 463.0
PYH3_k127_3889260_2 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000003279 229.0
PYH3_k127_3889260_3 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000001157 137.0
PYH3_k127_3896627_0 Aldehyde dehydrogenase family K00128,K22445 - 1.2.1.3,1.2.99.10 8.701e-215 678.0
PYH3_k127_3896627_1 Enoyl-(Acyl carrier protein) reductase K15734 - 1.1.1.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 295.0
PYH3_k127_3896627_2 Cupin domain K11312 - - 0.000000000000000000000000000000000000004656 148.0
PYH3_k127_3896627_3 - - - - 0.000000000001725 71.0
PYH3_k127_3916430_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.359e-202 645.0
PYH3_k127_3916430_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 557.0
PYH3_k127_3916430_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000006963 244.0
PYH3_k127_3916430_3 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000719 247.0
PYH3_k127_3916430_4 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000004397 245.0
PYH3_k127_391992_0 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 492.0
PYH3_k127_391992_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004121 424.0
PYH3_k127_391992_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000005114 58.0
PYH3_k127_3925911_0 Aminotransferase class-III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 503.0
PYH3_k127_3925911_1 Sulfotransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 380.0
PYH3_k127_3925911_2 Lysylphosphatidylglycerol synthase TM region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 293.0
PYH3_k127_3925911_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000004084 171.0
PYH3_k127_3925911_4 Peptidoglycan-binding domain 1 protein - - - 0.0000000000000000000000000000000000148 143.0
PYH3_k127_3927644_0 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 394.0
PYH3_k127_3927644_1 Mitochondrial biogenesis AIM24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 314.0
PYH3_k127_3927644_2 lipoprotein - - - 0.0000000000000000002382 89.0
PYH3_k127_3929217_0 PFAM Histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 436.0
PYH3_k127_3929217_1 PFAM CBS domain containing protein K04767 - - 0.00000000000000000000000000000000000008784 147.0
PYH3_k127_3929217_2 PFAM GAF domain protein - - - 0.0000000000000000000000000000000000007143 146.0
PYH3_k127_3929217_3 - - - - 0.000000000000000002264 91.0
PYH3_k127_3929217_4 - - - - 0.00002767 51.0
PYH3_k127_3942070_0 PFAM Aminotransferase class I and II K10206,K14261 - 2.6.1.83 2.108e-202 635.0
PYH3_k127_3942070_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 522.0
PYH3_k127_3942070_2 PFAM 2,3-bisphosphoglycerate-independent phosphoglycerate mutase K15635 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 464.0
PYH3_k127_3942070_3 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000005671 153.0
PYH3_k127_3942070_4 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000004929 52.0
PYH3_k127_3982115_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004177 590.0
PYH3_k127_3982115_1 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008997 464.0
PYH3_k127_3982115_2 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 331.0
PYH3_k127_3982115_3 aspartate kinase activity - - - 0.00000000000000000009381 92.0
PYH3_k127_3983697_0 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 413.0
PYH3_k127_3983697_1 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 392.0
PYH3_k127_3983697_2 PFAM AAA ATPase central domain protein K07478 - - 0.0000000000000000000000000000000000000001948 156.0
PYH3_k127_3983697_3 Protein of unknown function (DUF423) - - - 0.000002137 51.0
PYH3_k127_3998078_0 small subunit K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 411.0
PYH3_k127_3998078_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 306.0
PYH3_k127_3998078_2 PFAM Class III cytochrome C family - - - 0.000000000000000000000000000000000000000000000000000006085 193.0
PYH3_k127_3998078_3 PFAM 4Fe-4S ferredoxin - - - 0.000000000000000000000000001264 112.0
PYH3_k127_3998078_4 PFAM 4Fe-4S ferredoxin - - - 0.0000000000000000000000001145 106.0
PYH3_k127_3998078_5 Bacterial regulatory helix-turn-helix protein, lysR family K02019 - - 0.00000000000000000001515 95.0
PYH3_k127_3998078_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116,K03117 - - 0.0000000000000002363 83.0
PYH3_k127_4010023_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.317e-280 878.0
PYH3_k127_4010023_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0003674,GO:0003824,GO:0004812,GO:0004827,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006433,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017101,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.15 2.308e-204 644.0
PYH3_k127_4010023_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 489.0
PYH3_k127_4010023_3 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000000000006392 99.0
PYH3_k127_4010492_0 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 449.0
PYH3_k127_4010492_1 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 343.0
PYH3_k127_4010492_2 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 323.0
PYH3_k127_4010492_3 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000006313 208.0
PYH3_k127_4013811_0 diguanylate cyclase - - - 0.0000000000000000000116 103.0
PYH3_k127_4013811_1 Diguanylate cyclase - - - 0.00000000000000006659 92.0
PYH3_k127_4047026_0 Sigma-54 factor interaction domain-containing protein K02481,K07712,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 408.0
PYH3_k127_4059654_0 Displays ATPase and GTPase activities K06958 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 301.0
PYH3_k127_4059654_1 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003202 282.0
PYH3_k127_4059654_2 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000000000008 141.0
PYH3_k127_4059654_3 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000000001297 136.0
PYH3_k127_4059654_4 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion K06023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000001279 107.0
PYH3_k127_4061195_0 ADP-ribosylglycohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 339.0
PYH3_k127_4061195_1 Belongs to the glycosyl hydrolase 5 (cellulase A) family K01190 - 3.2.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000146 274.0
PYH3_k127_4061195_2 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00020,K00042,K18121 - 1.1.1.31,1.1.1.60,1.1.1.79 0.0000000000000000000000000000000000000000000000000000000001392 207.0
PYH3_k127_4061195_3 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000001411 217.0
PYH3_k127_4067378_0 Phosphodiester glycosidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 302.0
PYH3_k127_4067378_1 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000005555 197.0
PYH3_k127_4115287_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 9.008e-208 655.0
PYH3_k127_4157230_0 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000001145 234.0
PYH3_k127_4157230_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000001309 192.0
PYH3_k127_4168499_0 PP-loop family K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 287.0
PYH3_k127_4188272_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 503.0
PYH3_k127_4188272_1 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270,K21749 - 2.7.7.43,2.7.7.92,3.1.3.45 0.0000000000000000001616 94.0
PYH3_k127_4209179_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.0 1291.0
PYH3_k127_4209179_1 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the inner membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003,K05685 - - 8.147e-317 986.0
PYH3_k127_4209179_10 DNA-binding transcription factor activity - - - 0.00000000000000000000000000003493 122.0
PYH3_k127_4209179_11 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.00000000000000000000009151 99.0
PYH3_k127_4209179_12 Belongs to the 'phage' integrase family - - - 0.0000000000000000000007972 98.0
PYH3_k127_4209179_13 Helix-turn-helix XRE-family like proteins - - - 0.000002807 51.0
PYH3_k127_4209179_14 GAF domain - - - 0.000003198 55.0
PYH3_k127_4209179_2 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004351 581.0
PYH3_k127_4209179_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 547.0
PYH3_k127_4209179_4 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 526.0
PYH3_k127_4209179_5 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004698 342.0
PYH3_k127_4209179_6 Dihydrodipicolinate reductase, N-terminus K21672 - 1.4.1.12,1.4.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000002776 260.0
PYH3_k127_4209179_7 - - - - 0.000000000000000000000000000000000000000000000000000000000004041 214.0
PYH3_k127_4209179_8 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000004166 178.0
PYH3_k127_4209179_9 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000004502 148.0
PYH3_k127_4209563_0 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009722 518.0
PYH3_k127_4209563_1 AraC-like ligand binding domain - - - 0.000001149 50.0
PYH3_k127_4210678_0 Fumarase C C-terminus K01744 - 4.3.1.1 3.101e-209 662.0
PYH3_k127_4210678_1 Major facilitator K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 479.0
PYH3_k127_4210678_2 hexose biosynthetic process K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 327.0
PYH3_k127_4214381_0 PFAM Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 502.0
PYH3_k127_4214381_1 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 444.0
PYH3_k127_4214381_2 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 379.0
PYH3_k127_4214381_3 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000001031 212.0
PYH3_k127_4214381_4 peptidase m48, ste24p - - - 0.000000003643 66.0
PYH3_k127_4214381_5 ABC-type multidrug transport system ATPase component - - - 0.00000008543 63.0
PYH3_k127_4214381_6 - - - - 0.00006391 50.0
PYH3_k127_4216594_0 PFAM Extracellular ligand-binding receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009175 391.0
PYH3_k127_4216594_1 PFAM CBS domain K04767 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004371 243.0
PYH3_k127_4216594_2 response regulator - - - 0.000004655 54.0
PYH3_k127_4221374_0 BadF BadG BcrA BcrD - - - 5.106e-242 764.0
PYH3_k127_4233685_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 574.0
PYH3_k127_4233685_1 - - - - 0.000000000000000000000000000000000000000000156 168.0
PYH3_k127_4235789_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 2.042e-233 730.0
PYH3_k127_4235789_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 396.0
PYH3_k127_4235789_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000001283 53.0
PYH3_k127_4268390_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 3.32e-264 835.0
PYH3_k127_4268390_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 459.0
PYH3_k127_4268390_2 Hydrogenase accessory protein HypB K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007249 250.0
PYH3_k127_4268390_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000009872 84.0
PYH3_k127_4274215_0 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 369.0
PYH3_k127_4274215_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000001426 98.0
PYH3_k127_4281724_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007049 574.0
PYH3_k127_4281724_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K15372 - 2.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 364.0
PYH3_k127_4309080_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 449.0
PYH3_k127_4309080_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001149 284.0
PYH3_k127_4309080_2 Response regulator receiver - - - 0.000000000000000000000000000006961 137.0
PYH3_k127_4316907_0 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 503.0
PYH3_k127_4318332_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1055.0
PYH3_k127_4318332_1 acyl-coa dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 548.0
PYH3_k127_4346828_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008994 346.0
PYH3_k127_4346828_1 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000002059 162.0
PYH3_k127_4346828_2 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000003018 58.0
PYH3_k127_4351134_0 Psort location CytoplasmicMembrane, score K07793 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 531.0
PYH3_k127_4351134_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000001607 62.0
PYH3_k127_4363017_0 Fumarase C C-terminus K01679 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 548.0
PYH3_k127_4363017_1 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003274 408.0
PYH3_k127_4363017_2 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 362.0
PYH3_k127_4363017_3 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 334.0
PYH3_k127_4363017_4 - - - - 0.00000000000006723 81.0
PYH3_k127_4377542_0 RNB K01147,K12573 - 3.1.13.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 548.0
PYH3_k127_4377542_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 431.0
PYH3_k127_4406599_0 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 378.0
PYH3_k127_4406599_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000002759 178.0
PYH3_k127_4406599_2 - - - - 0.000000001377 66.0
PYH3_k127_4556051_0 aminopeptidase N K01256 - 3.4.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001517 572.0
PYH3_k127_4556051_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008743 395.0
PYH3_k127_4556051_3 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000002577 173.0
PYH3_k127_4556051_4 Bacterial SH3 domain K07184 - - 0.00000001502 58.0
PYH3_k127_4559103_0 Exopolysaccharide biosynthesis protein YbjH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 396.0
PYH3_k127_462106_0 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 369.0
PYH3_k127_462106_1 chain release factor K15034 - - 0.000000000000000000000000000000000002091 142.0
PYH3_k127_4625775_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.634e-274 857.0
PYH3_k127_4625775_1 PFAM Radical SAM domain protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 372.0
PYH3_k127_4625775_2 PFAM UspA domain protein - - - 0.000000000003088 69.0
PYH3_k127_4625775_3 - - - - 0.000000000433 63.0
PYH3_k127_464154_0 von Willebrand factor, type A K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 356.0
PYH3_k127_464154_1 PFAM CBS domain containing protein K04767 - - 0.0000000000000000972 81.0
PYH3_k127_4671335_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.0000000000000000000000000000000000000000000000000000000001005 223.0
PYH3_k127_4671335_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000003981 117.0
PYH3_k127_472359_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 0.0 1034.0
PYH3_k127_472359_1 2Fe-2S -binding domain K13483 - - 0.000000000000112 71.0
PYH3_k127_4757587_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 394.0
PYH3_k127_4757587_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008088 340.0
PYH3_k127_4757587_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
PYH3_k127_4757587_3 Putative regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000001455 207.0
PYH3_k127_4757587_4 - - - - 0.000000000000000000000000000000000000000000000000000001701 198.0
PYH3_k127_4757587_5 Belongs to the HesB IscA family - - - 0.00000000007634 64.0
PYH3_k127_4757587_6 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.00000001073 60.0
PYH3_k127_4757587_7 EamA-like transporter family - - - 0.00000008622 60.0
PYH3_k127_4771329_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 2.589e-300 933.0
PYH3_k127_4771329_1 PFAM tRNA synthetases class I (E and Q), catalytic domain K01886 - 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000001626 226.0
PYH3_k127_4793925_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 350.0
PYH3_k127_4793925_1 PFAM ABC transporter K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000002837 220.0
PYH3_k127_4793925_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000001236 92.0
PYH3_k127_4810339_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000007218 231.0
PYH3_k127_4810339_1 cytochrome C - - - 0.000000000000000000000000000000000008897 140.0
PYH3_k127_4811770_0 PFAM EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 347.0
PYH3_k127_4811770_1 PFAM AzlC family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001133 275.0
PYH3_k127_4811770_2 Branched-chain amino acid transport protein (AzlD) - - - 0.000000000000000000000000000003086 123.0
PYH3_k127_4811770_3 radical SAM domain protein - - - 0.00000009772 61.0
PYH3_k127_4834528_0 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000001571 206.0
PYH3_k127_4834528_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.00000000000000000000000000000000000031 143.0
PYH3_k127_4834528_2 CoA binding domain - - - 0.0002839 44.0
PYH3_k127_4858547_0 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 432.0
PYH3_k127_4881995_0 Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) K00768 - 2.4.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 409.0
PYH3_k127_4881995_1 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.000000000000000000000000000000000000000000003433 175.0
PYH3_k127_4894505_0 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 602.0
PYH3_k127_4894505_1 Pyruvate phosphate dikinase, PEP/pyruvate binding domain K01007 - 2.7.9.2 0.000002662 57.0
PYH3_k127_4913457_0 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 535.0
PYH3_k127_4913457_1 SMART phosphoesterase PHP domain protein K07053 - 3.1.3.97 0.000000000000000000000000000000000000000000000000000000000000000000000001985 254.0
PYH3_k127_4913457_2 beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001315 234.0
PYH3_k127_4916099_0 Binding-protein-dependent transport system inner membrane component K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 327.0
PYH3_k127_4916099_1 ABC transporter K02028 - 3.6.3.21 0.000000000000000000000000000000000000000000000000000000000000000001154 231.0
PYH3_k127_4916188_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.244e-320 1001.0
PYH3_k127_4916188_1 TIGRFAM clan AA aspartic protease, AF_0612 family - - - 0.000000000000000000000000000000000000000000000000009361 186.0
PYH3_k127_4923308_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 2.678e-231 734.0
PYH3_k127_4923308_1 ATPase domain of DNA mismatch repair MUTS family K07456 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004536 460.0
PYH3_k127_4923308_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 394.0
PYH3_k127_4923308_3 Ribonuclease H K03469 - 3.1.26.4 0.00000000000000000000000000000000000174 145.0
PYH3_k127_4923308_4 C4-type zinc ribbon domain K07164 - - 0.00000000000000000000000000000003514 135.0
PYH3_k127_4939593_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 319.0
PYH3_k127_4939593_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000002263 114.0
PYH3_k127_4943373_0 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000202 338.0
PYH3_k127_4943373_1 PFAM Endonuclease Exonuclease phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 304.0
PYH3_k127_4943373_2 - - - - 0.00000000000000000000000000000000003764 140.0
PYH3_k127_4943373_3 ROS/MUCR transcriptional regulator protein - - - 0.0000000000000000000000004234 111.0
PYH3_k127_4943815_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003059 594.0
PYH3_k127_4943815_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 571.0
PYH3_k127_4943815_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 554.0
PYH3_k127_4943815_3 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 425.0
PYH3_k127_4943815_4 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000003183 151.0
PYH3_k127_4943815_5 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000002324 128.0
PYH3_k127_4943815_6 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000004165 109.0
PYH3_k127_4943815_7 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000002665 68.0
PYH3_k127_4961016_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 451.0
PYH3_k127_4961016_1 Belongs to the ompA family - - - 0.000000000000000000000000000000000000000000000000004709 188.0
PYH3_k127_4961016_2 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000000001516 168.0
PYH3_k127_4961016_3 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000001095 158.0
PYH3_k127_4961016_4 PIN domain - - - 0.000000000000000000000000000000000000000002137 161.0
PYH3_k127_4961016_6 - - - - 0.0000000000000000002056 96.0
PYH3_k127_4969190_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 355.0
PYH3_k127_4969190_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002746 280.0
PYH3_k127_4975128_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 1.295e-262 818.0
PYH3_k127_4975128_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 3.155e-202 636.0
PYH3_k127_4975128_10 GlcNAc-PI de-N-acetylase K01463 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 289.0
PYH3_k127_4975128_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000008441 260.0
PYH3_k127_4975128_12 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000001138 222.0
PYH3_k127_4975128_13 Glycoprotease family K01409,K14742 - 2.3.1.234 0.00000000000000000000000000000000000000000000000000000001326 205.0
PYH3_k127_4975128_14 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000003349 207.0
PYH3_k127_4975128_15 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000003074 182.0
PYH3_k127_4975128_16 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000001801 145.0
PYH3_k127_4975128_17 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022411,GO:0032984,GO:0034641,GO:0034645,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000001611 113.0
PYH3_k127_4975128_18 PFAM glycosyl transferase group 1 K15521 - 2.4.1.250 0.0000000000000000000009234 99.0
PYH3_k127_4975128_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 558.0
PYH3_k127_4975128_20 TIGRFAM HAD-superfamily hydrolase subfamily IA, variant 3 K07025 - - 0.0000000000000000000138 100.0
PYH3_k127_4975128_3 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004035 535.0
PYH3_k127_4975128_4 1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000221 447.0
PYH3_k127_4975128_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 404.0
PYH3_k127_4975128_6 Lysin motif K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000981 359.0
PYH3_k127_4975128_7 PDZ domain (Also known as DHR or GLGF) K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 353.0
PYH3_k127_4975128_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002314 303.0
PYH3_k127_4975128_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 295.0
PYH3_k127_4975452_0 PFAM type II secretion system K02455,K02653 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007476 414.0
PYH3_k127_4975452_1 PFAM Type II secretion system protein E K02454 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 307.0
PYH3_k127_4984120_0 SMART Elongator protein 3 MiaB NifB K22227 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 499.0
PYH3_k127_4984120_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002691 442.0
PYH3_k127_4984120_2 GAF domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004755 275.0
PYH3_k127_4984120_3 SMART Transcription regulator, AsnC-type - - - 0.000000000000000000000000000000000000000000000000002701 187.0
PYH3_k127_4984120_4 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000002517 154.0
PYH3_k127_4986249_0 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000327 406.0
PYH3_k127_4986249_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000006704 199.0
PYH3_k127_4995001_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003167 383.0
PYH3_k127_4998570_0 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005098 480.0
PYH3_k127_4998570_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 448.0
PYH3_k127_503370_0 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 6.197e-276 868.0
PYH3_k127_503370_1 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 582.0
PYH3_k127_503370_10 reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000000000009286 87.0
PYH3_k127_503370_2 Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 553.0
PYH3_k127_503370_3 Peptidase family U32 K08303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 459.0
PYH3_k127_503370_4 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 426.0
PYH3_k127_503370_5 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 396.0
PYH3_k127_503370_6 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533,K15396 - 2.1.1.200 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 299.0
PYH3_k127_503370_7 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002286 273.0
PYH3_k127_503370_8 PFAM Phosphoglycerate mutase K02226 - 3.1.3.73 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
PYH3_k127_503370_9 PGAP1-like protein - - - 0.000000000000000000000000000000000002206 149.0
PYH3_k127_5039675_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.173e-200 635.0
PYH3_k127_5039675_1 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000001286 193.0
PYH3_k127_5039675_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.00000005622 55.0
PYH3_k127_5046500_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 379.0
PYH3_k127_5046500_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000148 215.0
PYH3_k127_5051681_0 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 391.0
PYH3_k127_5051681_1 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004292 342.0
PYH3_k127_5051681_2 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000002409 120.0
PYH3_k127_5051681_3 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000005698 82.0
PYH3_k127_5056813_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.379e-256 805.0
PYH3_k127_5056813_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 348.0
PYH3_k127_5056813_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.00000000000008283 72.0
PYH3_k127_5061723_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007942 297.0
PYH3_k127_5061723_1 PFAM ABC transporter related K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000006586 243.0
PYH3_k127_5061723_2 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000001844 203.0
PYH3_k127_5061723_3 Biopolymer transport protein ExbD TolR K03559 - - 0.00000000000000000000001378 106.0
PYH3_k127_5067939_0 Arginyl tRNA synthetase N terminal dom K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 2.935e-203 650.0
PYH3_k127_5067939_1 Protein tyrosine kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005148 465.0
PYH3_k127_5067939_2 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005497 278.0
PYH3_k127_5067939_3 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000009608 191.0
PYH3_k127_5067939_4 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000003713 157.0
PYH3_k127_5067939_5 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000002956 71.0
PYH3_k127_5067939_6 domain, Protein K01181,K08300,K08301 - 3.1.26.12,3.2.1.8 0.00000000003119 73.0
PYH3_k127_5075113_0 Formyl transferase, C-terminal domain K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000549 246.0
PYH3_k127_5075113_1 - - - - 0.0000000000000000000000000000000001617 144.0
PYH3_k127_5075113_2 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.000000000000000000000000002813 117.0
PYH3_k127_5075113_3 Belongs to the thioredoxin family K03671,K03672 GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.1.8 0.000000000000000000000001973 109.0
PYH3_k127_5078744_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 524.0
PYH3_k127_5078744_1 Anion-transporting ATPase K01551 - 3.6.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 327.0
PYH3_k127_5085920_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001993 572.0
PYH3_k127_5085920_1 haloacid dehalogenase-like hydrolase - - - 0.0004226 45.0
PYH3_k127_5088482_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001745 239.0
PYH3_k127_5088482_1 Undecaprenyl-phosphate galactose phosphotransferase - - - 0.00000000000000000004239 90.0
PYH3_k127_5090496_0 PFAM Enoyl-CoA hydratase isomerase K01782,K01825 - 1.1.1.35,4.2.1.17,5.1.2.3,5.3.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 602.0
PYH3_k127_5110502_0 DNA photolyase K01669 - 4.1.99.3 2.588e-200 633.0
PYH3_k127_5110502_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006337 273.0
PYH3_k127_5110502_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000003957 173.0
PYH3_k127_5112803_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 1.169e-208 652.0
PYH3_k127_5112803_1 Mo-molybdopterin cofactor metabolic process - - - 0.0000000000000000001204 90.0
PYH3_k127_5123916_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 343.0
PYH3_k127_5123916_1 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000007525 230.0
PYH3_k127_5131081_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1089.0
PYH3_k127_5131081_1 sigma-54 factor interaction domain-containing protein K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002119 263.0
PYH3_k127_5131081_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.0000000000000003234 83.0
PYH3_k127_5149157_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 6.855e-232 728.0
PYH3_k127_5149157_1 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 644.0
PYH3_k127_5149157_2 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009213 268.0
PYH3_k127_516939_0 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007517 394.0
PYH3_k127_516939_1 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006685 391.0
PYH3_k127_516939_2 Branched-chain amino acid transport system / permease component K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005648 376.0
PYH3_k127_516939_3 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000613 359.0
PYH3_k127_516939_4 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002384 304.0
PYH3_k127_516939_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001212 278.0
PYH3_k127_516939_6 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K11206 - - 0.00000000000000000000000000000000000000000000000000000000000579 218.0
PYH3_k127_516939_7 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000002937 210.0
PYH3_k127_516939_8 Asparaginase K01424 - 3.5.1.1 0.000000000000000000000000000000000000000002375 168.0
PYH3_k127_516939_9 EamA-like transporter family K08978 - - 0.0000000000000000000000000002346 119.0
PYH3_k127_5184654_0 Oxidoreductase family, NAD-binding Rossmann fold K09949 - - 2.271e-198 636.0
PYH3_k127_5184654_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 364.0
PYH3_k127_5184654_2 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 291.0
PYH3_k127_5184654_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000001041 182.0
PYH3_k127_5184654_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.00000000000006237 72.0
PYH3_k127_5184654_5 PFAM Outer membrane K06142 - - 0.0000000002139 70.0
PYH3_k127_5190156_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 2.992e-291 900.0
PYH3_k127_5196462_0 Type III restriction enzyme, res subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 413.0
PYH3_k127_5196462_1 RimK-like ATP-grasp domain K05844 - - 0.00000000000000000000000000000000000000000000000000000000000000575 225.0
PYH3_k127_5207592_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 5.602e-219 689.0
PYH3_k127_521465_0 S4 RNA-binding domain K06178,K06183 - 5.4.99.19,5.4.99.22 0.00000000000000000000000000000000001869 139.0
PYH3_k127_521465_1 Anaphase-promoting complex, cyclosome, subunit 3 K06665 GO:0000122,GO:0000228,GO:0000785,GO:0000790,GO:0000988,GO:0000989,GO:0001076,GO:0001190,GO:0001191,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0005737,GO:0006139,GO:0006323,GO:0006325,GO:0006333,GO:0006338,GO:0006342,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016043,GO:0016070,GO:0016458,GO:0016584,GO:0017053,GO:0018130,GO:0019216,GO:0019217,GO:0019219,GO:0019222,GO:0019438,GO:0019899,GO:0022607,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031497,GO:0031974,GO:0031981,GO:0032774,GO:0032879,GO:0032991,GO:0034641,GO:0034645,GO:0034654,GO:0034728,GO:0035950,GO:0035952,GO:0035953,GO:0035955,GO:0040029,GO:0042304,GO:0042826,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044451,GO:0044454,GO:0044464,GO:0045814,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0045944,GO:0046483,GO:0046890,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051276,GO:0060255,GO:0062012,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071824,GO:0071840,GO:0072364,GO:0080090,GO:0080134,GO:0080135,GO:0090087,GO:0090088,GO:0090089,GO:0090304,GO:0090568,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2000531,GO:2000877,GO:2000879,GO:2001020,GO:2001141 - 0.000000000000006216 89.0
PYH3_k127_5238612_0 tRNA synthetase class II core domain (G, H, P, S and T) K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008937 487.0
PYH3_k127_5239558_0 FAD linked oxidases, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 384.0
PYH3_k127_5239558_1 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000000000000005139 232.0
PYH3_k127_5239558_2 PFAM Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.0000000000000000000000000000000000006069 144.0
PYH3_k127_5239558_3 Glycosyl hydrolase family 63 C-terminal domain - - - 0.00000003252 56.0
PYH3_k127_5239558_4 DinB superfamily - - - 0.0000005342 57.0
PYH3_k127_5255800_0 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000001693 184.0
PYH3_k127_5255800_1 tRNA synthetases class II (D, K and N) K01893 - 6.1.1.22 0.00000000000000000000002458 98.0
PYH3_k127_5255800_2 Helix-turn-helix domain K15539 - - 0.0000000000000000000001427 109.0
PYH3_k127_5279375_0 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000007778 182.0
PYH3_k127_5279375_1 CHAT domain - - - 0.000000000000000000000000000000006284 148.0
PYH3_k127_5279375_2 - - - - 0.00000001893 64.0
PYH3_k127_5283597_0 self proteolysis - - - 0.000000000000000000000000000000000000004119 157.0
PYH3_k127_5283597_1 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.00000000001837 64.0
PYH3_k127_5290029_0 Domain of unknown function (DUF4338) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007812 272.0
PYH3_k127_5290029_1 PFAM Transposase DDE domain - - - 0.00000006049 66.0
PYH3_k127_5290029_2 PFAM Transposase - - - 0.00002706 57.0
PYH3_k127_5298985_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 3.113e-235 742.0
PYH3_k127_5298985_1 Binding-protein-dependent transport system inner membrane component K02033,K12369 - - 0.0000000000000008983 78.0
PYH3_k127_5298985_2 Tellurite resistance protein TehB - - - 0.0000000000001035 80.0
PYH3_k127_5308368_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.607e-276 860.0
PYH3_k127_5308368_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 8.122e-238 759.0
PYH3_k127_5308368_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 483.0
PYH3_k127_5308368_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0006996,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000000000005094 226.0
PYH3_k127_5308368_4 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000001745 153.0
PYH3_k127_5308368_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000002265 147.0
PYH3_k127_5308368_6 helix_turn_helix, mercury resistance - - - 0.0000000000000000000002443 102.0
PYH3_k127_5308368_7 Ribosomal protein L35 K02916 - - 0.000000000000000001281 87.0
PYH3_k127_5308368_8 - - - - 0.000000006988 68.0
PYH3_k127_5308368_9 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0009424 46.0
PYH3_k127_5322377_0 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 1.676e-206 655.0
PYH3_k127_5322377_1 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 342.0
PYH3_k127_5322377_2 Ribose/Galactose Isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000000000004042 199.0
PYH3_k127_5322377_3 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000001252 184.0
PYH3_k127_5322377_4 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000008944 120.0
PYH3_k127_5332890_0 DNA polymerase type-B family K02336 - 2.7.7.7 4.474e-262 824.0
PYH3_k127_5332890_1 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 329.0
PYH3_k127_5332890_2 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000005247 130.0
PYH3_k127_5332890_3 Anion-transporting ATPase K01551 - 3.6.3.16 0.00000000000000000000000000000003153 130.0
PYH3_k127_5332890_4 Transposase IS200 like - - - 0.000000000000000000000000001407 117.0
PYH3_k127_53405_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 495.0
PYH3_k127_53405_1 protein conserved in bacteria (DUF2179) - - - 0.000000000000000000000000000000000000000000000000000000000000005026 223.0
PYH3_k127_53405_2 Iron/manganese superoxide dismutases, alpha-hairpin domain K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000001088 205.0
PYH3_k127_53405_3 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000608 91.0
PYH3_k127_5348064_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1072.0
PYH3_k127_5348064_1 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001905 449.0
PYH3_k127_5348064_2 Rhomboid family K19225 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 331.0
PYH3_k127_5348064_3 - - - - 0.000000000000000000000000000000000000000002051 164.0
PYH3_k127_5348064_4 PFAM Phosphoglycerate mutase K08296 - - 0.0000000001329 64.0
PYH3_k127_5364214_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1113.0
PYH3_k127_5364214_1 Asparaginyl-tRNA synthetase K01893 GO:0003674,GO:0003824,GO:0004812,GO:0004816,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006421,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 590.0
PYH3_k127_5364214_2 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 542.0
PYH3_k127_5364214_3 BioY family K03523 - - 0.00000000000000000000000000000000000000000003081 168.0
PYH3_k127_5364214_4 peptidyl-prolyl cis-trans isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000004332 170.0
PYH3_k127_5369342_0 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 364.0
PYH3_k127_5369342_1 PDZ domain (Also known as DHR or GLGF) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001694 280.0
PYH3_k127_5369342_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.0000000000000000000000001469 107.0
PYH3_k127_5369342_3 Putative Na+/H+ antiporter - - - 0.000000000000001316 78.0
PYH3_k127_5377926_0 ABC1 family K03688 - - 3.181e-222 702.0
PYH3_k127_5377926_1 PFAM HhH-GPD superfamily base excision DNA repair protein K07457 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002016 243.0
PYH3_k127_5397044_0 elongation factor Tu domain 2 protein K02355 - - 1.436e-245 779.0
PYH3_k127_5397044_1 Phage integrase, N-terminal SAM-like domain K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008684 284.0
PYH3_k127_5397044_2 molybdenum cofactor K03638,K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000001606 212.0
PYH3_k127_5397044_3 - - - - 0.00000000000000000000000000001114 124.0
PYH3_k127_5401783_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 3.7e-273 854.0
PYH3_k127_5401783_1 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 541.0
PYH3_k127_5401783_2 PFAM Type II IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003673 535.0
PYH3_k127_5401783_3 PFAM Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000008131 245.0
PYH3_k127_5401783_4 Pfam SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000005754 187.0
PYH3_k127_5401783_5 zinc-ribbon domain - - - 0.0000000000000000000000000000000000009774 157.0
PYH3_k127_5401783_6 - - - - 0.000000001405 61.0
PYH3_k127_5401783_7 - - - - 0.0003037 48.0
PYH3_k127_5404493_0 ABC transporter transmembrane region K06147,K18889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005488 543.0
PYH3_k127_5404493_1 ABC transporter transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004412 534.0
PYH3_k127_5404493_2 Uncharacterized protein family (UPF0051) K07033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 465.0
PYH3_k127_5404493_3 EamA-like transporter family - - - 0.00001661 47.0
PYH3_k127_5407589_0 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 439.0
PYH3_k127_5407589_1 Binding-protein-dependent transport system inner membrane component K02034,K12370 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004092 401.0
PYH3_k127_5407589_2 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003404 405.0
PYH3_k127_5407589_3 PFAM Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000003718 261.0
PYH3_k127_5407589_4 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000252 239.0
PYH3_k127_5473864_0 Putative ATP-binding cassette K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001665 443.0
PYH3_k127_5473864_1 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000000000000000000000000000000000002306 222.0
PYH3_k127_5473864_2 Surface antigen K07278 - - 0.0000000000000000000002871 105.0
PYH3_k127_5480687_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 556.0
PYH3_k127_5480687_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000009853 236.0
PYH3_k127_5480687_2 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000002074 173.0
PYH3_k127_5480687_3 Putative zinc- or iron-chelating domain - - - 0.0000000000000000000000000000000000000001079 158.0
PYH3_k127_5499812_0 Protein of unknown function, DUF255 K06888 - - 2.432e-283 886.0
PYH3_k127_5499812_1 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009573 252.0
PYH3_k127_5499812_2 Rubrerythrin - - - 0.00000000000000000000002516 100.0
PYH3_k127_5499812_3 Flavodoxin - - - 0.0000000000000004317 79.0
PYH3_k127_5499812_4 part of a sulfur-relay system - - - 0.00000000000959 67.0
PYH3_k127_5501118_0 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006274 484.0
PYH3_k127_5501118_1 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 373.0
PYH3_k127_5501118_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000008541 214.0
PYH3_k127_5509776_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 434.0
PYH3_k127_5509776_1 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000003773 168.0
PYH3_k127_5516277_0 Radical SAM domain protein K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000156 249.0
PYH3_k127_5521942_0 Aldehyde dehydrogenase family K00128,K00135 - 1.2.1.16,1.2.1.20,1.2.1.3,1.2.1.79 1.141e-209 663.0
PYH3_k127_5521942_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001861 284.0
PYH3_k127_5521942_2 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000002838 146.0
PYH3_k127_5521942_3 Tetratricopeptide repeat - - - 0.0000000000000001793 91.0
PYH3_k127_5545022_0 Belongs to the FPP GGPP synthase family K02523,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 373.0
PYH3_k127_5545022_1 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007016 351.0
PYH3_k127_5545022_2 AsmA-like C-terminal region K07289 - - 0.00000000000000000000000000000000000000000000000000000000000000000807 251.0
PYH3_k127_5545022_3 protein kinase activity - - - 0.000000000000000000000000000000001734 134.0
PYH3_k127_5574795_0 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 550.0
PYH3_k127_5583663_0 Belongs to the peptidase S16 family - - - 2.646e-227 729.0
PYH3_k127_5583663_1 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 462.0
PYH3_k127_5583663_2 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000003861 244.0
PYH3_k127_5583663_3 HAD-hyrolase-like - - - 0.00000000000000000000000000000000000265 148.0
PYH3_k127_5583663_4 - - - - 0.000000000000000000000000000003096 122.0
PYH3_k127_5583663_5 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000004912 100.0
PYH3_k127_5585054_0 reverse transcriptase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 548.0
PYH3_k127_5585054_1 KH domain K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 300.0
PYH3_k127_5585054_2 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000001989 201.0
PYH3_k127_5585054_3 Glycerol-3-phosphate acyltransferase K08591 - 2.3.1.15 0.000000000000000000000000000000000003434 146.0
PYH3_k127_5585054_4 Domain of unknown function (DUF3842) - - - 0.00000000000000000000000002271 111.0
PYH3_k127_5585054_5 Fimbrial assembly family protein K02461 - - 0.000000000000000000000001745 119.0
PYH3_k127_5585054_6 Type II secretion system (T2SS), protein M K02462 - - 0.00000000000000942 82.0
PYH3_k127_5600173_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 514.0
PYH3_k127_5600173_1 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 312.0
PYH3_k127_5600173_2 Domain amino terminal to FKBP-type peptidyl-prolyl isomerase K03772,K03773 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000006456 228.0
PYH3_k127_5600173_3 Hydroxymethylglutaryl-coenzyme A reductase K00021 - 1.1.1.34 0.000000000000000000000000000000000000001931 156.0
PYH3_k127_5600173_4 - - - - 0.0000000000000000000000000003053 115.0
PYH3_k127_5600173_5 diguanylate cyclase - - - 0.00000000000000000000002625 115.0
PYH3_k127_5615398_0 Domain of unknown function (DUF362) K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002474 474.0
PYH3_k127_5615398_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 392.0
PYH3_k127_5615398_2 aminomethyltransferase activity K02437 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005960,GO:0006082,GO:0006464,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009249,GO:0009987,GO:0010467,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0018065,GO:0018193,GO:0018205,GO:0019464,GO:0019538,GO:0019752,GO:0019899,GO:0031974,GO:0032259,GO:0032991,GO:0036211,GO:0042133,GO:0042135,GO:0042737,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044267,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0051604,GO:0065007,GO:0065008,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 - 0.000000000000000000000000000004454 126.0
PYH3_k127_5615398_3 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352 - 1.8.5.5 0.00000000000000001165 83.0
PYH3_k127_5624825_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000963 431.0
PYH3_k127_5624825_1 Bacterial extracellular solute-binding protein, family 7 K11688,K21395 - - 0.00000000000000000000000000000000000000000000000000000000002021 220.0
PYH3_k127_5624825_2 TRAP transporter T-component - - - 0.0000000000000000000000000000000000000000000000006259 186.0
PYH3_k127_5624825_3 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.0000000000000000000000000000000000001268 143.0
PYH3_k127_5624825_4 Trap-type c4-dicarboxylate transport system, small permease component K11689 - - 0.0000000000000000000000143 114.0
PYH3_k127_5639787_0 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000002058 205.0
PYH3_k127_5639787_1 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.000000000000000000000000000002259 123.0
PYH3_k127_5702793_0 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 6.273e-198 638.0
PYH3_k127_5702793_1 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 590.0
PYH3_k127_5702793_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 516.0
PYH3_k127_5702793_3 PFAM ATP-binding region ATPase domain protein K02482,K10819 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004414 442.0
PYH3_k127_5702793_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003533 382.0
PYH3_k127_5702793_5 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 378.0
PYH3_k127_5702793_6 cheY-homologous receiver domain K07658 - - 0.00000000000000000002022 97.0
PYH3_k127_5702793_7 ACT domain K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006520,GO:0006553,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016020,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0019877,GO:0030312,GO:0040007,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046451,GO:0071704,GO:0071944,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.4 0.000001061 57.0
PYH3_k127_5709736_0 cytochrome c nitrate reductase, small subunit K15876 - - 0.000000000000000000000000000000000000000000000000000000000002524 211.0
PYH3_k127_5709736_1 SMART Rhodanese domain protein - - - 0.0000000000000000000000000001909 126.0
PYH3_k127_5709736_2 B-1 B cell differentiation - - - 0.00000000000000000009568 100.0
PYH3_k127_5743407_0 ABC transporter, transmembrane region - - - 0.0 1025.0
PYH3_k127_5743407_1 PFAM NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005366 269.0
PYH3_k127_5743407_2 SMART Protein phosphatase K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000001414 169.0
PYH3_k127_5743407_3 PFAM Cyclic nucleotide-binding - - - 0.0000000000000000000000000000000006853 137.0
PYH3_k127_5743407_4 transporter antisigma-factor antagonist STAS K04749 - - 0.0000000000000000000000000000001292 128.0
PYH3_k127_5743407_5 anti-sigma regulatory factor, serine threonine protein kinase K04757 - 2.7.11.1 0.0000000000000000000000000000236 123.0
PYH3_k127_5754825_0 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 376.0
PYH3_k127_5754825_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 304.0
PYH3_k127_5754825_2 amidohydrolase - - - 0.000000000955 61.0
PYH3_k127_579102_0 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000004695 208.0
PYH3_k127_579102_1 FMN_bind - - - 0.0000003997 62.0
PYH3_k127_579102_2 phosphate-selective porin O and P - - - 0.0003809 52.0
PYH3_k127_5823991_0 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 280.0
PYH3_k127_5823991_1 PFAM metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000001576 228.0
PYH3_k127_5885495_0 Alpha/beta hydrolase family K07019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001806 420.0
PYH3_k127_5894741_0 sigma54 specific, transcriptional regulator, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 387.0
PYH3_k127_5894741_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 372.0
PYH3_k127_5894741_2 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 293.0
PYH3_k127_5894741_3 - - - - 0.000000000000000000000000000000000000000000000000000008293 196.0
PYH3_k127_59044_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1511.0
PYH3_k127_59044_1 - - - - 0.000000653 53.0
PYH3_k127_591949_0 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000004671 175.0
PYH3_k127_591949_1 regulation of response to stimulus K01406,K13730 - 3.4.24.40 0.00000000000005435 76.0
PYH3_k127_592143_0 Phosphorylase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000006262 223.0
PYH3_k127_592143_1 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000009225 109.0
PYH3_k127_5951292_0 PFAM Metal-dependent phosphohydrolase, HD K06951 - - 0.0000000000000000000000000000000000000000000000000006138 191.0
PYH3_k127_5951292_1 - - - - 0.0000000000000000000000000002713 117.0
PYH3_k127_5951292_2 PFAM Band 7 protein - - - 0.0000000000000000001491 89.0
PYH3_k127_5981292_0 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000008936 188.0
PYH3_k127_5981292_1 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.0000000000000000003849 93.0
PYH3_k127_5981292_2 to GB Z34005 SP P39209 GB D30762 PID 496484 PID 710635 percent identity K03406 - - 0.000000005847 68.0
PYH3_k127_6006234_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.651e-224 706.0
PYH3_k127_6006234_1 tail specific protease K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 423.0
PYH3_k127_6006234_2 Met-10+ like-protein K15460 - 2.1.1.223 0.000000000000000000000000000000000000000006593 164.0
PYH3_k127_6006234_3 - - - - 0.000000000000000001291 89.0
PYH3_k127_6006234_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000003313 75.0
PYH3_k127_6047068_0 cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008713 393.0
PYH3_k127_6047068_1 heavy metal translocating P-type ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 386.0
PYH3_k127_6047068_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000004101 169.0
PYH3_k127_6047068_3 - - - - 0.0000000000000000000000000004787 118.0
PYH3_k127_6047068_4 - - - - 0.0000000000000000000004183 97.0
PYH3_k127_6047068_5 Cytochrome oxidase maturation protein - - - 0.00000000000000000868 86.0
PYH3_k127_6058795_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 336.0
PYH3_k127_6063174_0 mannitol 2-dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000249 192.0
PYH3_k127_6063174_1 EamA-like transporter family - - - 0.0001006 55.0
PYH3_k127_6119234_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 7.677e-224 703.0
PYH3_k127_6119363_0 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007827 511.0
PYH3_k127_6119363_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008056 300.0
PYH3_k127_6119363_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000001733 157.0
PYH3_k127_6119363_3 PFAM Nucleotidyl transferase K00963 - 2.7.7.9 0.00000000000000000000000000001572 128.0
PYH3_k127_6119363_4 Protein of unknown function (DUF4255) - - - 0.000000000000000000000179 100.0
PYH3_k127_6132531_0 TIGRFAM argininosuccinate lyase K01755 GO:0003674,GO:0003824,GO:0004056,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016842,GO:0019752,GO:0042450,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009852 344.0
PYH3_k127_6139078_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 454.0
PYH3_k127_6139078_1 pfkB family carbohydrate kinase K00847,K00852 - 2.7.1.15,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 363.0
PYH3_k127_6139078_2 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000001114 181.0
PYH3_k127_6139078_3 HAD-hyrolase-like - - - 0.000000000000000000000001495 110.0
PYH3_k127_6152934_0 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18023 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000003232 252.0
PYH3_k127_6152934_1 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000005211 248.0
PYH3_k127_6152934_2 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K18017 - 1.12.7.2 0.00000000000000000000000000000000000000000000000000000000003884 213.0
PYH3_k127_6152934_3 Proton-conducting membrane transporter K05568 - - 0.000000000000000000000000000000000000006486 147.0
PYH3_k127_6152934_4 - - - - 0.000000000000000000000000000000000002091 143.0
PYH3_k127_6157318_0 L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000006524 157.0
PYH3_k127_6157318_1 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.0000000000000000000000001508 111.0
PYH3_k127_6157318_2 Regulatory protein, FmdB family - - - 0.00000000000000000008195 91.0
PYH3_k127_6157318_3 Uncharacterized protein family UPF0016 - - - 0.0000000000000000005572 90.0
PYH3_k127_6157318_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000001269 56.0
PYH3_k127_6157318_5 PFAM nuclease (SNase domain protein) - - - 0.0000008834 50.0
PYH3_k127_6172397_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 2.49e-221 690.0
PYH3_k127_6172397_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 503.0
PYH3_k127_6172397_10 Prephenate dehydrogenase K04517,K14187 - 1.3.1.12,5.4.99.5 0.0000000000000000000000000000000000000000006329 168.0
PYH3_k127_6172397_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000000000000000007108 150.0
PYH3_k127_6172397_12 PFAM Pentapeptide repeats (8 copies) - - - 0.0000000000000000000000000000000001494 147.0
PYH3_k127_6172397_13 PFAM type II secretion system protein E K02652 - - 0.0002536 52.0
PYH3_k127_6172397_2 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18,4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 430.0
PYH3_k127_6172397_3 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002041 401.0
PYH3_k127_6172397_4 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 374.0
PYH3_k127_6172397_5 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001555 282.0
PYH3_k127_6172397_6 with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine K01658,K01664 - 2.6.1.85,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008608 267.0
PYH3_k127_6172397_7 Tryptophan synthase alpha chain K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000001182 254.0
PYH3_k127_6172397_8 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000000001158 225.0
PYH3_k127_6172397_9 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000007331 220.0
PYH3_k127_6179343_0 nucleic acid binding K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006076 315.0
PYH3_k127_6179343_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000000000000000000002574 209.0
PYH3_k127_6181097_0 TrkA-N domain K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 367.0
PYH3_k127_6181097_1 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000003347 173.0
PYH3_k127_6181097_2 Cyclic nucleotide binding domain protein - - - 0.000000000000000000000000000000000000001109 157.0
PYH3_k127_6181097_3 YbbR-like protein - - - 0.00000000000005816 78.0
PYH3_k127_6205657_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.514e-221 692.0
PYH3_k127_6205657_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003727 481.0
PYH3_k127_6205657_10 Belongs to the universal ribosomal protein uS5 family K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000003989 243.0
PYH3_k127_6205657_11 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001261 214.0
PYH3_k127_6205657_12 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000001455 213.0
PYH3_k127_6205657_13 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000003104 213.0
PYH3_k127_6205657_14 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000006211 216.0
PYH3_k127_6205657_15 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007225 206.0
PYH3_k127_6205657_16 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001265 207.0
PYH3_k127_6205657_17 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16784,K16786 - - 0.00000000000000000000000000000000000000000000000000007712 196.0
PYH3_k127_6205657_18 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000526 184.0
PYH3_k127_6205657_19 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000899 174.0
PYH3_k127_6205657_2 Threonine aldolase K01620 - 4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 373.0
PYH3_k127_6205657_20 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000007734 169.0
PYH3_k127_6205657_21 helix_turn_helix, cAMP Regulatory protein K01420,K21563 - - 0.000000000000000000000000000000000000000000002063 175.0
PYH3_k127_6205657_22 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000003115 165.0
PYH3_k127_6205657_23 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000131 155.0
PYH3_k127_6205657_24 One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02895 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000001776 154.0
PYH3_k127_6205657_25 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000426 146.0
PYH3_k127_6205657_26 ATP-binding (A) component of a common energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16786,K16787 - - 0.0000000000000000000000000000000000001191 152.0
PYH3_k127_6205657_27 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000004244 137.0
PYH3_k127_6205657_28 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000002278 127.0
PYH3_k127_6205657_29 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001104 112.0
PYH3_k127_6205657_3 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002234 336.0
PYH3_k127_6205657_30 TPR repeat - - - 0.0000000000000004466 92.0
PYH3_k127_6205657_31 PFAM ribosomal protein L30 K02907 - - 0.000000000000003123 76.0
PYH3_k127_6205657_32 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000006973 72.0
PYH3_k127_6205657_33 structural constituent of ribosome K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000002662 72.0
PYH3_k127_6205657_34 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00002841 57.0
PYH3_k127_6205657_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 331.0
PYH3_k127_6205657_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 317.0
PYH3_k127_6205657_6 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000095 317.0
PYH3_k127_6205657_7 Metallopeptidase family M24 K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 311.0
PYH3_k127_6205657_8 acyl-coa dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 287.0
PYH3_k127_6205657_9 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 287.0
PYH3_k127_6228637_0 Triosephosphate isomerase K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002327 269.0
PYH3_k127_6228637_1 methionine synthase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000113 193.0
PYH3_k127_6228637_2 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000000004105 103.0
PYH3_k127_6228637_3 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000002044 66.0
PYH3_k127_6230263_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 4.952e-237 751.0
PYH3_k127_6230263_1 HELICc2 K03722 GO:0003674,GO:0003824,GO:0004386,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008026,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:1901360 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 540.0
PYH3_k127_6230263_2 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 496.0
PYH3_k127_6230263_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000001175 153.0
PYH3_k127_6237073_0 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004917 599.0
PYH3_k127_6237073_1 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 335.0
PYH3_k127_6237073_2 PFAM ParB domain protein nuclease K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005686 263.0
PYH3_k127_6237073_3 YacP-like NYN domain K06962 - - 0.0000000000000000000000000000006304 129.0
PYH3_k127_6237073_4 Universal stress protein family - - - 0.00000000000000000000000000007953 121.0
PYH3_k127_6237073_5 - - - - 0.0000000000000000000000005491 108.0
PYH3_k127_6237073_6 Protein of unknown function DUF89 - - - 0.000000000000006727 75.0
PYH3_k127_6238288_0 Protein involved in outer membrane biogenesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000225 259.0
PYH3_k127_6238288_2 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000001395 85.0
PYH3_k127_6238288_3 PFAM Tetratricopeptide - - - 0.0000361 56.0
PYH3_k127_6238995_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 567.0
PYH3_k127_6238995_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000008311 164.0
PYH3_k127_6238995_2 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000006639 123.0
PYH3_k127_6253876_0 Elongation factor Tu domain 2 K03833 - - 3.203e-233 737.0
PYH3_k127_6253876_1 Ftsk_gamma K03466 - - 4.543e-207 666.0
PYH3_k127_6253876_2 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004488 404.0
PYH3_k127_6253876_3 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 346.0
PYH3_k127_6253876_4 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003043 254.0
PYH3_k127_6253876_5 Metallo-beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003756 255.0
PYH3_k127_6253876_6 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000000000000001185 222.0
PYH3_k127_6253876_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000000000000000000000000002492 120.0
PYH3_k127_6253876_8 PFAM thioesterase superfamily - - - 0.0000000000003067 76.0
PYH3_k127_6259436_0 Oligopeptidase F K08602 - - 1.441e-197 632.0
PYH3_k127_6259436_1 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000001281 181.0
PYH3_k127_6259436_2 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000001733 169.0
PYH3_k127_6259436_3 - - - - 0.00003883 50.0
PYH3_k127_6276672_0 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 9.243e-233 729.0
PYH3_k127_6276672_2 Alpha/beta hydrolase family K06889 - - 0.0000000000004189 71.0
PYH3_k127_6288299_0 PFAM Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1105.0
PYH3_k127_6288299_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1077.0
PYH3_k127_6288299_10 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000008623 121.0
PYH3_k127_6288299_11 PFAM methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000000000001246 101.0
PYH3_k127_6288299_12 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000007405 99.0
PYH3_k127_6288299_13 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.0000000000001393 70.0
PYH3_k127_6288299_2 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 7.891e-289 893.0
PYH3_k127_6288299_3 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 6.285e-265 844.0
PYH3_k127_6288299_4 two component, sigma54 specific, transcriptional regulator, Fis family K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002705 541.0
PYH3_k127_6288299_5 PFAM Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 530.0
PYH3_k127_6288299_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003331 385.0
PYH3_k127_6288299_7 heterodisulfide reductase, subunit K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 353.0
PYH3_k127_6288299_8 PFAM molybdopterin oxidoreductase Fe4S4 region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002211 260.0
PYH3_k127_6288299_9 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000054 280.0
PYH3_k127_6291384_0 oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002967 604.0
PYH3_k127_6291384_1 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002934 455.0
PYH3_k127_6291384_2 Converts GTP to 7,8-dihydroneopterin triphosphate K09007 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005895 376.0
PYH3_k127_6291384_3 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003105 327.0
PYH3_k127_6291384_4 Domain of unknown function (DUF3786) - - - 0.00000000000000000000000000000000000000000003138 170.0
PYH3_k127_6291384_5 Universal stress protein family K06149 - - 0.0000000000000000000000000000000000001059 147.0
PYH3_k127_6291384_6 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.0000000000000000000009046 103.0
PYH3_k127_6291384_7 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000001466 70.0
PYH3_k127_6291384_8 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0008996 43.0
PYH3_k127_6346846_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 597.0
PYH3_k127_6346846_1 Uncharacterized ACR, COG1399 K07040 - - 0.0000000000000000000000000000000000001233 151.0
PYH3_k127_6346846_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000002912 89.0
PYH3_k127_6346846_3 structural constituent of ribosome K02911 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000001025 87.0
PYH3_k127_6361332_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002885 260.0
PYH3_k127_6361332_1 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001499 255.0
PYH3_k127_6361332_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.00000000000000000000000000000000000000000000000000000000000001228 223.0
PYH3_k127_6361332_3 - - - - 0.00000003734 60.0
PYH3_k127_6364134_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000002927 193.0
PYH3_k127_6364134_1 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.00000000000000000000000000000000000000000000000007093 192.0
PYH3_k127_6364134_2 PFAM RimK domain protein ATP-grasp K05844 - - 0.00000000000000000000000000000000006508 142.0
PYH3_k127_6378747_0 Belongs to the thiolase family K00626 - 2.3.1.9 2.715e-200 629.0
PYH3_k127_6378747_1 MaoC domain protein dehydratase K00634,K17865 - 2.3.1.19,4.2.1.55 0.0000000000000000000000000000000000008664 145.0
PYH3_k127_6378747_2 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.000000000002147 69.0
PYH3_k127_6380312_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 9.143e-280 881.0
PYH3_k127_6380312_1 CoA binding domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 626.0
PYH3_k127_6380312_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003149 273.0
PYH3_k127_6380312_3 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000001415 180.0
PYH3_k127_6380312_4 DNA recombination-mediator protein A K04096 - - 0.000000000000000000000000006638 114.0
PYH3_k127_6380312_6 RDD family - - - 0.0000001229 63.0
PYH3_k127_6380312_8 Prokaryotic N-terminal methylation motif - - - 0.0006963 48.0
PYH3_k127_6383166_0 HAD-hyrolase-like K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 297.0
PYH3_k127_6383166_1 Phosphotransferase enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000627 288.0
PYH3_k127_6384616_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000007809 194.0
PYH3_k127_6384616_1 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.0000000000000000000000000000000000000002947 164.0
PYH3_k127_6384616_2 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000008473 103.0
PYH3_k127_6423426_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 402.0
PYH3_k127_6423426_1 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006145 273.0
PYH3_k127_6423426_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000001245 103.0
PYH3_k127_644152_0 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000042 449.0
PYH3_k127_644152_1 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 359.0
PYH3_k127_644152_2 CoA binding domain K01905,K22224 - 6.2.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006575 290.0
PYH3_k127_644152_3 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007938 281.0
PYH3_k127_644152_4 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001667 261.0
PYH3_k127_644152_5 Methyltransferase - - - 0.00000000000000000000000001295 122.0
PYH3_k127_6441792_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009817 342.0
PYH3_k127_6441792_1 Transposase - - - 0.00000000000000000000000000000000000000000000000000000000000000000002562 245.0
PYH3_k127_6441792_2 Zincin-like metallopeptidase - - - 0.000000000000000000000000000000000000000000000005393 176.0
PYH3_k127_6441792_3 antisigma factor binding - - - 0.000000000000000000000005645 112.0
PYH3_k127_6441792_4 amino acid - - - 0.0000000000000003762 84.0
PYH3_k127_6441792_5 Oligopeptidase F K08602 - - 0.0001959 44.0
PYH3_k127_6441792_6 membrane transporter protein K07090 - - 0.0008836 48.0
PYH3_k127_6446302_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006389 500.0
PYH3_k127_6446302_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001362 377.0
PYH3_k127_6446302_2 Cytidylate kinase-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001677 245.0
PYH3_k127_6446302_3 PFAM Integral membrane protein TerC - - - 0.000000000002147 69.0
PYH3_k127_6472675_0 Exodeoxyribonuclease iii K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 290.0
PYH3_k127_6472675_1 Putative regulatory protein - - - 0.000008012 50.0
PYH3_k127_6472675_2 AAA domain K07028 - - 0.0002299 47.0
PYH3_k127_6479927_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003431 436.0
PYH3_k127_653262_0 VWA containing CoxE family protein K09989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007986 434.0
PYH3_k127_653262_1 AAA domain (Cdc48 subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 422.0
PYH3_k127_653262_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 372.0
PYH3_k127_6547068_0 Fad linked oxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000338 553.0
PYH3_k127_6547068_1 UbiA prenyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 459.0
PYH3_k127_6547068_2 short-chain dehydrogenase reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 306.0
PYH3_k127_6547068_3 - - - - 0.0000000000000000000000000007266 125.0
PYH3_k127_6547068_4 PAP2 superfamily C-terminal - - - 0.000000000928 64.0
PYH3_k127_6547081_0 PFAM major facilitator superfamily MFS_1 K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 504.0
PYH3_k127_6547081_1 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 482.0
PYH3_k127_6547081_10 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000001117 92.0
PYH3_k127_6547081_2 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 362.0
PYH3_k127_6547081_3 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 354.0
PYH3_k127_6547081_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0008150,GO:0008152,GO:0009056,GO:0016491,GO:0044464,GO:0055114,GO:0071704,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000009833 209.0
PYH3_k127_6547081_5 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000004003 165.0
PYH3_k127_6547081_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000002677 156.0
PYH3_k127_6547081_7 Pilus assembly protein, PilP K02664,K02665 - - 0.0000000000000000000000007509 108.0
PYH3_k127_6547081_8 Peptidyl-prolyl cis-trans isomerase K03775 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0006457,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0036211,GO:0042026,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 5.2.1.8 0.0000000000000000000003176 102.0
PYH3_k127_6547081_9 metal cluster binding K18475 - - 0.00000000000000000002377 101.0
PYH3_k127_6547666_0 PFAM aldo keto reductase K07079 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 456.0
PYH3_k127_6547666_1 PIN domain - - - 0.000000000000000000000000000000009726 131.0
PYH3_k127_6547666_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000005186 121.0
PYH3_k127_6551155_0 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000002844 197.0
PYH3_k127_6562649_0 Biotin carboxylase C-terminal domain K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 7.689e-221 695.0
PYH3_k127_6562649_1 pyruvate K01571,K01958,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 389.0
PYH3_k127_6562649_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 324.0
PYH3_k127_6562649_3 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000006952 149.0
PYH3_k127_6562649_4 Rubredoxin-type Fe(Cys)4 protein - - - 0.000000000000000000000000038 108.0
PYH3_k127_65690_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 5.429e-202 634.0
PYH3_k127_65690_1 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000008019 116.0
PYH3_k127_65690_2 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.0000000000000000000001663 100.0
PYH3_k127_6607979_0 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 411.0
PYH3_k127_6607979_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 359.0
PYH3_k127_6610630_0 phosphoribosyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003829 254.0
PYH3_k127_6610630_1 PFAM Sulfate transporter antisigma-factor antagonist STAS K03321 - - 0.00000000000000000000000000000000000000000000000000001434 197.0
PYH3_k127_6610630_2 Thioesterase superfamily - - - 0.0000000000000000000001115 100.0
PYH3_k127_6663251_0 DNA polymerase A domain K02335 - 2.7.7.7 1.208e-227 730.0
PYH3_k127_6663251_1 - - - - 0.0000000000000000000000000000000000000000009221 162.0
PYH3_k127_6663251_2 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 GO:0003674,GO:0003824,GO:0003887,GO:0004518,GO:0004527,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008409,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.000000000000000000003582 94.0
PYH3_k127_6709976_0 ABC-type transport system involved in resistance to organic solvents periplasmic component K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 411.0
PYH3_k127_6709976_1 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 323.0
PYH3_k127_6709976_2 PFAM ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002746 318.0
PYH3_k127_6709976_3 Divergent polysaccharide deacetylase K09798 - - 0.0000000000000000000000000000000000000000000000000000001117 211.0
PYH3_k127_6709976_4 Response regulator receiver - - - 0.0000000000000002008 85.0
PYH3_k127_6709976_5 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000001284 71.0
PYH3_k127_6711155_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.17e-208 657.0
PYH3_k127_6711155_1 Belongs to the MurCDEF family K02558 - 6.3.2.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003916 509.0
PYH3_k127_6711155_2 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 378.0
PYH3_k127_6711155_3 PFAM Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 309.0
PYH3_k127_6711155_4 PFAM peptidase U61 LD-carboxypeptidase A K01297 - 3.4.17.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000004785 275.0
PYH3_k127_6711155_5 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796,K13941 - 2.5.1.15,2.7.6.3 0.000000000000000000000000000000000000000000000000005141 186.0
PYH3_k127_6711155_6 PFAM GAF domain - - - 0.000000000000000000000000000000000000000003273 161.0
PYH3_k127_674087_0 PFAM AsmA family protein K07290 - - 0.0000000000000000000000000000000000005635 162.0
PYH3_k127_674087_1 PFAM AsmA family protein K07290 - - 0.000000000000000000000000001315 132.0
PYH3_k127_6754774_0 Dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 314.0
PYH3_k127_6754774_1 PFAM UspA domain protein - - - 0.000000000000000000000000000000000000000000008252 175.0
PYH3_k127_6766228_0 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 599.0
PYH3_k127_6766228_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 421.0
PYH3_k127_6863513_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 430.0
PYH3_k127_6863513_1 PFAM ATP-binding region ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 429.0
PYH3_k127_6863513_2 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000022 308.0
PYH3_k127_6863513_3 Tetratricopeptide repeat - - - 0.0000000003602 70.0
PYH3_k127_6868647_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 443.0
PYH3_k127_6868647_1 PFAM aminotransferase class V - - - 0.000000000000000000000000000000000000000000000000000000000000006315 220.0
PYH3_k127_6868647_2 peroxiredoxin activity K01607 - 4.1.1.44 0.000000000000000000000000000000000002673 138.0
PYH3_k127_6868647_3 peroxiredoxin activity K01607 - 4.1.1.44 0.000000001752 59.0
PYH3_k127_6871376_0 Xylose isomerase-like TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 413.0
PYH3_k127_6871376_1 PFAM Smr protein MutS2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 413.0
PYH3_k127_6871376_2 FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005652 295.0
PYH3_k127_6871376_3 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 288.0
PYH3_k127_6871376_4 Aldehyde dehydrogenase family - - - 0.00000000000000000000000001781 125.0
PYH3_k127_6871376_5 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.0000009189 52.0
PYH3_k127_6918536_0 histidine kinase, HAMP K13598 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 572.0
PYH3_k127_6918536_1 response regulator receiver K13599 - - 0.0000000000000000002502 88.0
PYH3_k127_6925033_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 445.0
PYH3_k127_6925033_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 308.0
PYH3_k127_6925033_2 ATPases associated with a variety of cellular activities K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000001568 244.0
PYH3_k127_6925033_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000005593 237.0
PYH3_k127_6925033_4 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000001931 190.0
PYH3_k127_6956359_0 Histidine kinase K07709 - 2.7.13.3 0.0000000000000000000000000000000000000002542 162.0
PYH3_k127_6956359_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 0.000000002674 60.0
PYH3_k127_6967244_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 - 5.4.99.13 0.0 1054.0
PYH3_k127_7037912_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008681 585.0
PYH3_k127_7037912_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001944 535.0
PYH3_k127_7037912_2 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000008902 169.0
PYH3_k127_7037912_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000009213 154.0
PYH3_k127_7037912_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000006925 150.0
PYH3_k127_7037912_5 elongation factor Tu domain 2 protein K06207 - - 0.00000000000000000000000000000000000006132 143.0
PYH3_k127_7037912_6 Thioesterase superfamily K02614 - - 0.000000000000000000000000000000000007913 140.0
PYH3_k127_7051276_0 - - - - 2.49e-206 671.0
PYH3_k127_7063082_0 PFAM ATP-binding region ATPase domain protein K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 613.0
PYH3_k127_7063082_1 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 404.0
PYH3_k127_7063082_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000000000000002041 185.0
PYH3_k127_7065089_0 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 452.0
PYH3_k127_7065089_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003776 379.0
PYH3_k127_7065089_2 Two component transcriptional regulator, winged helix family K02483,K07662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002863 297.0
PYH3_k127_7094963_0 membrane carboxypeptidase (Penicillin-binding protein) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006198 265.0
PYH3_k127_7094963_1 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000000003832 128.0
PYH3_k127_7094963_2 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000001472 121.0
PYH3_k127_712401_0 PFAM NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000000000000008246 211.0
PYH3_k127_712401_1 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000006051 156.0
PYH3_k127_712401_2 PFAM alpha beta hydrolase fold K01048 - 3.1.1.5 0.0000000001561 73.0
PYH3_k127_712401_3 pyridine nucleotide-disulphide oxidoreductase dimerisation - - - 0.00003737 50.0
PYH3_k127_712401_4 Helix-turn-helix XRE-family like proteins - - - 0.0002641 50.0
PYH3_k127_7190029_0 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006879 333.0
PYH3_k127_7190029_1 Belongs to the alkaline phosphatase family K01077 - 3.1.3.1 0.0000000000005406 72.0
PYH3_k127_7245035_0 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 468.0
PYH3_k127_7245035_1 DNA polymerase III alpha subunit K02337,K14162 - 2.7.7.7 0.00000000000000001636 88.0
PYH3_k127_7245035_2 - - - - 0.000001894 53.0
PYH3_k127_7245355_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2064.0
PYH3_k127_7245355_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000004674 152.0
PYH3_k127_7245355_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000001143 154.0
PYH3_k127_7245355_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000007452 65.0
PYH3_k127_7365803_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 413.0
PYH3_k127_7365803_1 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000642 376.0
PYH3_k127_7365803_2 PFAM Phosphomethylpyrimidine kinase type-1 K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 300.0
PYH3_k127_7367473_0 Involved in the TonB-independent uptake of proteins K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 393.0
PYH3_k127_7367473_1 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007919 259.0
PYH3_k127_7367473_2 Biopolymer transport protein ExbD/TolR K03560 - - 0.000000000000000000000000000000000000005524 149.0
PYH3_k127_7367473_3 energy transducer activity K03646,K03832 - - 0.0000000004308 70.0
PYH3_k127_7401598_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 579.0
PYH3_k127_7401598_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008585 417.0
PYH3_k127_7401598_2 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 401.0
PYH3_k127_7401598_3 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 356.0
PYH3_k127_7403334_0 nitrogen compound transport K02033,K13894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009422 426.0
PYH3_k127_7403334_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 364.0
PYH3_k127_7403334_2 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000553 356.0
PYH3_k127_7403334_3 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002543 336.0
PYH3_k127_7403334_4 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.00000000000000000000000000000000000000000000000000007319 192.0
PYH3_k127_7415328_0 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 1.341e-196 625.0
PYH3_k127_7415328_1 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 351.0
PYH3_k127_7415328_2 Putative regulatory protein - - - 0.00000000000000000000005791 99.0
PYH3_k127_7429383_0 Thiamine pyrophosphate enzyme, central domain K03852 - 2.3.3.15 1.352e-306 946.0
PYH3_k127_7429383_1 NMT1-like family K02051,K15553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003838 459.0
PYH3_k127_7429383_2 ABC transporter K15555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001533 399.0
PYH3_k127_7429383_3 Aminotransferase class-III K15372 - 2.6.1.55 0.000000000000000000000309 100.0
PYH3_k127_7436831_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 604.0
PYH3_k127_7436831_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000001987 156.0
PYH3_k127_7449404_0 Phosphoglucomutase/phosphomannomutase, C-terminal domain K01835 GO:0000271,GO:0003674,GO:0003824,GO:0004614,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0005996,GO:0006006,GO:0006012,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016052,GO:0016853,GO:0016866,GO:0016868,GO:0019318,GO:0019320,GO:0019388,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0055114,GO:0071704,GO:1901575,GO:1901576 5.4.2.2 8.468e-278 862.0
PYH3_k127_7449404_1 PFAM FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 555.0
PYH3_k127_7449404_2 Rhomboid family K07059 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 369.0
PYH3_k127_7449404_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 329.0
PYH3_k127_7449404_4 ThiF family - - - 0.000000000000000000000000000000000001235 156.0
PYH3_k127_7449404_5 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877 - 0.0000000000000000000000000000000002358 133.0
PYH3_k127_7466232_0 NUDIX hydrolase - - - 0.0000000000000000000000000000000000000000000000001982 181.0
PYH3_k127_7466232_1 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000001662 87.0
PYH3_k127_7466232_2 PFAM Forkhead-associated protein - - - 0.00000000009839 74.0
PYH3_k127_7466232_3 Shikimate kinase K00891 - 2.7.1.71 0.00000001472 59.0
PYH3_k127_7487853_0 Pyridine nucleotide-disulphide oxidoreductase K00123 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002338 515.0
PYH3_k127_7487853_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000008151 171.0
PYH3_k127_7487853_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000776 48.0
PYH3_k127_7490763_0 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003608 305.0
PYH3_k127_7490763_1 - - - - 0.0000000000000000000000000000000000000000000001437 175.0
PYH3_k127_7490763_2 PAS domain K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000002346 139.0
PYH3_k127_7490763_3 Transcription factor zinc-finger K09981 - - 0.000000000002812 73.0
PYH3_k127_7513554_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 1.692e-267 833.0
PYH3_k127_7520260_0 Type IV pilus assembly protein PilM; K02662 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 350.0
PYH3_k127_7520260_1 type II and III secretion system protein K02666 - - 0.00000000000000000000000000000000000000000000000000000000000000000004567 258.0
PYH3_k127_7520260_2 PFAM Pilus assembly protein PilO K02664 - - 0.0000000000000000000000000000000000000001785 158.0
PYH3_k127_7520260_3 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000002653 126.0
PYH3_k127_7534709_0 Putative citrate transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004042 540.0
PYH3_k127_7534709_1 SelR domain K07305,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 520.0
PYH3_k127_7534709_10 mitochondrion organization K10374 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005741,GO:0005773,GO:0005774,GO:0006996,GO:0007005,GO:0008150,GO:0009536,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019867,GO:0031090,GO:0031224,GO:0031300,GO:0031301,GO:0031306,GO:0031307,GO:0031966,GO:0031967,GO:0031968,GO:0031975,GO:0032592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044425,GO:0044429,GO:0044437,GO:0044444,GO:0044446,GO:0044455,GO:0044464,GO:0071840,GO:0098573,GO:0098588,GO:0098805 - 0.0009967 46.0
PYH3_k127_7534709_2 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001393 315.0
PYH3_k127_7534709_3 Inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000003656 258.0
PYH3_k127_7534709_4 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000157 225.0
PYH3_k127_7534709_5 Protein of unknown function (DUF1178) - - - 0.0000000000000000000000000000000009395 134.0
PYH3_k127_7534709_6 Domain of unknown function (DUF4833) - - - 0.0000000000000004076 86.0
PYH3_k127_7534709_8 synthetase (ADP forming), alpha K01905,K22224 - 6.2.1.13 0.000005658 49.0
PYH3_k127_7534709_9 PFAM Peptidase family M28 - - - 0.000009362 57.0
PYH3_k127_7536139_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 527.0
PYH3_k127_7536139_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002935 340.0
PYH3_k127_7622807_0 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 428.0
PYH3_k127_7622807_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000001577 238.0
PYH3_k127_7622807_2 HNH nucleases - - - 0.000000000000000000000000000000000000000000762 159.0
PYH3_k127_7623650_0 radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002168 463.0
PYH3_k127_7623650_1 PFAM Uracil-DNA glycosylase superfamily K10800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 337.0
PYH3_k127_7623650_2 NlpC/P60 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003748 267.0
PYH3_k127_7623650_3 PFAM Enoyl-CoA hydratase isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000004238 242.0
PYH3_k127_7623712_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 452.0
PYH3_k127_7623712_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 329.0
PYH3_k127_7623712_2 Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000006022 164.0
PYH3_k127_7623712_3 NADH-Ubiquinone oxidoreductase (complex I) chain 5 L domain protein K00341 - 1.6.5.3 0.000000000000000000000000000000000000405 145.0
PYH3_k127_7623712_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000003309 141.0
PYH3_k127_7623712_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000008974 125.0
PYH3_k127_7623712_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be a menaquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340,K05576 - 1.6.5.3 0.00000000000000000000003584 104.0
PYH3_k127_7623712_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000002674 89.0
PYH3_k127_7624551_0 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 504.0
PYH3_k127_7624551_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 354.0
PYH3_k127_7624859_0 TIGRFAM phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002154 295.0
PYH3_k127_7624859_1 Yqey-like protein K09117 - - 0.0000000000000000000000000000000001609 139.0
PYH3_k127_7624859_2 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000008432 100.0
PYH3_k127_7625865_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K13598 - 2.7.13.3 2.137e-194 636.0
PYH3_k127_7625865_1 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 564.0
PYH3_k127_7625865_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535,K13599 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009686 316.0
PYH3_k127_7625865_3 Domain of unknown function (DUF4390) - - - 0.0000000000000000000000000000000000000000000000000000004288 198.0
PYH3_k127_7625865_4 response regulator, receiver - - - 0.00000000000000000009254 99.0
PYH3_k127_7636129_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.097e-274 878.0
PYH3_k127_7636129_1 PFAM CBS domain K03699 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 492.0
PYH3_k127_7636129_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001656 236.0
PYH3_k127_7636129_3 Patatin-like phospholipase - - - 0.00000000000000000000000000000000000000000000000000000000001076 212.0
PYH3_k127_7636129_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000002673 183.0
PYH3_k127_7636129_5 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000008779 108.0
PYH3_k127_7636129_6 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000004202 91.0
PYH3_k127_7656920_0 Amino acid permease - - - 0.00000000000000000000000000000000000000000000000000000003731 200.0
PYH3_k127_7659208_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455,K11747 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 496.0
PYH3_k127_7659208_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000005293 64.0
PYH3_k127_7681414_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.1e-205 647.0
PYH3_k127_7681414_1 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000005285 209.0
PYH3_k127_7683850_0 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005457 366.0
PYH3_k127_7683850_1 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 329.0
PYH3_k127_7683850_2 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000128 264.0
PYH3_k127_7683850_3 WbqC-like protein family - - - 0.000000000000000000000000000000000000000000000000000000000000000005784 234.0
PYH3_k127_7683850_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.0000000000004431 70.0
PYH3_k127_769734_0 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000594 481.0
PYH3_k127_769734_1 - - - - 0.0000000000000000000000000000003813 133.0
PYH3_k127_769734_2 Lipid A biosynthesis K02517 - 2.3.1.241 0.00009243 46.0
PYH3_k127_7711381_0 PAS fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 349.0
PYH3_k127_7712889_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 576.0
PYH3_k127_7712889_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 453.0
PYH3_k127_7712889_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 362.0
PYH3_k127_7712889_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007265 312.0
PYH3_k127_7712889_4 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000000002608 175.0
PYH3_k127_7730451_0 PFAM Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 376.0
PYH3_k127_7730451_1 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 297.0
PYH3_k127_7730451_2 TIGRFAM methylmalonyl-CoA mutase C-terminal domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000002901 214.0
PYH3_k127_7741042_0 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 299.0
PYH3_k127_7741042_1 Glycosyl transferase, family 2 - - - 0.0000000000002588 81.0
PYH3_k127_7741042_2 HEAT repeats - - - 0.00000008886 58.0
PYH3_k127_7741042_3 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.0000007814 57.0
PYH3_k127_7741102_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 4.585e-309 972.0
PYH3_k127_7754834_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 389.0
PYH3_k127_7754834_1 3'(2'),5'-bisphosphate nucleotidase activity K01082 - 3.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001119 281.0
PYH3_k127_7754834_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000003078 164.0
PYH3_k127_7754834_3 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000008556 147.0
PYH3_k127_7754834_4 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0001907 45.0
PYH3_k127_7769431_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 289.0
PYH3_k127_7769431_1 MOSC domain containing protein - - - 0.00000000000000000000000000000000000000000000000000001929 193.0
PYH3_k127_7769431_2 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000001063 173.0
PYH3_k127_7769431_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000001409 60.0
PYH3_k127_7775535_0 Signal transduction response regulator, receiver domain K02030 - - 1.289e-203 666.0
PYH3_k127_7775535_1 - - - - 0.000000008682 65.0
PYH3_k127_7783940_0 PFAM Type II secretion system protein E K02454,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 476.0
PYH3_k127_7783940_1 ATP-binding region, ATPase domain protein K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 443.0
PYH3_k127_7783940_2 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005237 421.0
PYH3_k127_7783940_3 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003336 352.0
PYH3_k127_7783940_4 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000024 259.0
PYH3_k127_7783940_5 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000363 239.0
PYH3_k127_7783940_6 PFAM MCP methyltransferase CheR-type K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000002892 234.0
PYH3_k127_7783940_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.000000000000000000000000000000000000000000000000004724 205.0
PYH3_k127_7783940_8 COGs COG0835 Chemotaxis signal transduction protein K03408 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006935,GO:0007154,GO:0007165,GO:0008150,GO:0009605,GO:0009893,GO:0009987,GO:0010604,GO:0016020,GO:0019222,GO:0019904,GO:0023052,GO:0031323,GO:0031325,GO:0031399,GO:0031401,GO:0032268,GO:0032270,GO:0032991,GO:0040011,GO:0042221,GO:0042330,GO:0044424,GO:0044444,GO:0044464,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051246,GO:0051247,GO:0051641,GO:0051649,GO:0051716,GO:0060255,GO:0065007,GO:0071944,GO:0080090,GO:0098561,GO:1901873,GO:1901875 - 0.000000000000000007805 91.0
PYH3_k127_7789759_0 PIN domain - - - 0.0000000000000000000000000000000000000000000000003606 181.0
PYH3_k127_7789759_1 RES - - - 0.0000000000000000000000000000000006853 137.0
PYH3_k127_7789759_2 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000009527 123.0
PYH3_k127_7789759_3 - - - - 0.000000000000001517 79.0
PYH3_k127_7789759_4 Protein of unknown function (DUF2384) - - - 0.0004566 43.0
PYH3_k127_7813207_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 5.199e-243 773.0
PYH3_k127_7813207_1 Scavenger mRNA decapping enzyme C-term binding K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000445 258.0
PYH3_k127_7813207_2 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000003908 236.0
PYH3_k127_7856510_0 SMART metal-dependent phosphohydrolase HD region K01129 - 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 481.0
PYH3_k127_7856510_1 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000166 122.0
PYH3_k127_7856510_2 nUDIX hydrolase K01515 - 3.6.1.13 0.0000000000000000000000000642 117.0
PYH3_k127_7868183_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 327.0
PYH3_k127_7889808_0 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002277 394.0
PYH3_k127_7889808_1 FtsX-like permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000144 272.0
PYH3_k127_7889808_2 PFAM Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003228 258.0
PYH3_k127_7889808_3 Glycosyltransferase family 28 C-terminal domain - - - 0.000000000594 62.0
PYH3_k127_7907467_0 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000005922 234.0
PYH3_k127_7907467_1 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16783,K16785 - - 0.000000000000000000000000000000000000000006593 164.0
PYH3_k127_7907467_2 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000000000009485 160.0
PYH3_k127_7957438_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005248 555.0
PYH3_k127_7957438_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000003957 216.0
PYH3_k127_7957438_2 4Fe-4S dicluster domain K00184 - - 0.0000000001623 62.0
PYH3_k127_79739_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 507.0
PYH3_k127_7975381_0 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 300.0
PYH3_k127_7975381_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000008448 260.0
PYH3_k127_7975381_2 PFAM DivIVA family protein K04074 - - 0.0000000000000000000000000000000000002872 146.0
PYH3_k127_7975381_3 integral membrane protein K02221 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000547 138.0
PYH3_k127_7975381_4 Belongs to the UPF0235 family K09131 - - 0.00000000000000000000429 97.0
PYH3_k127_7975381_5 - - - - 0.000000000000003747 77.0
PYH3_k127_8005580_0 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 - 2.10.1.1 3.936e-231 732.0
PYH3_k127_8005580_1 TIGRFAM molybdenum cofactor synthesis domain K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 433.0
PYH3_k127_8005580_2 metal-dependent phosphohydrolase HD region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007255 307.0
PYH3_k127_8005594_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 603.0
PYH3_k127_8005594_1 protein phosphatase 2C domain protein K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 575.0
PYH3_k127_8005594_2 Thi4 family K03146 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005139 379.0
PYH3_k127_8005594_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007245 381.0
PYH3_k127_8005594_4 PFAM Alcohol dehydrogenase GroES domain protein K00008 - 1.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007552 282.0
PYH3_k127_8005594_5 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000000000004113 206.0
PYH3_k127_8010256_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 8.636e-202 645.0
PYH3_k127_8010256_1 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 304.0
PYH3_k127_8010256_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003918 273.0
PYH3_k127_8010256_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000001555 214.0
PYH3_k127_8010256_4 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000003863 180.0
PYH3_k127_8010256_5 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000001016 147.0
PYH3_k127_8010256_6 KH domain K06960 - - 0.0000000000000000000000000000001114 128.0
PYH3_k127_8010256_7 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000000009128 126.0
PYH3_k127_8010256_8 Phosphocarrier protein HPr K08485,K11189 - - 0.00000000000000000000003241 102.0
PYH3_k127_8010256_9 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0004845 45.0
PYH3_k127_8031112_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 406.0
PYH3_k127_8031112_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000009939 84.0
PYH3_k127_8031112_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.00000000000004331 72.0
PYH3_k127_8032542_0 PFAM binding-protein-dependent transport systems inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 480.0
PYH3_k127_8032542_1 Nucleoside recognition - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 474.0
PYH3_k127_8032542_2 O-acyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008319 294.0
PYH3_k127_8032542_3 peptidyl-tyrosine sulfation - - - 0.0000000000000002257 90.0
PYH3_k127_8035345_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 480.0
PYH3_k127_8035345_1 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000002715 216.0
PYH3_k127_8046158_0 PFAM Bacterial regulatory protein, Fis family - - - 1.078e-204 645.0
PYH3_k127_8046158_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 411.0
PYH3_k127_8046158_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000002898 138.0
PYH3_k127_8046158_3 Roadblock/LC7 domain K07131 - - 0.00000000006405 64.0
PYH3_k127_8046158_4 Roadblock/LC7 domain K07131 - - 0.00001442 55.0
PYH3_k127_8066415_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 489.0
PYH3_k127_8066415_1 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 362.0
PYH3_k127_8066415_2 PHP domain protein K07053 - 3.1.3.97 0.0000000000000000000000000000000000000003406 152.0
PYH3_k127_8068531_0 PFAM Major Facilitator Superfamily K08218 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005274 484.0
PYH3_k127_8068531_1 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 461.0
PYH3_k127_8068531_2 Thymidylate synthase K00560 - 2.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006956 285.0
PYH3_k127_8068531_3 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001849 276.0
PYH3_k127_8068531_4 PFAM Prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 0.0000000000608 67.0
PYH3_k127_8068531_5 - - - - 0.00002242 48.0
PYH3_k127_8075303_0 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 615.0
PYH3_k127_8075303_1 aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 543.0
PYH3_k127_8075303_2 ATP phosphoribosyltransferase K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 464.0
PYH3_k127_8075303_3 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 314.0
PYH3_k127_8075303_4 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 279.0
PYH3_k127_8075303_5 Necessary for normal cell division and for the maintenance of normal septation K03978 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000002792 220.0
PYH3_k127_8075303_6 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000007311 196.0
PYH3_k127_8075303_7 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496 - 3.5.4.19 0.000000000000000000000000000000000000000000000000000007973 192.0
PYH3_k127_8075303_8 Protein of unknown function (DUF1285) K09986 - - 0.00000000000000000000000000000002652 132.0
PYH3_k127_8075303_9 Tetratricopeptide repeat - - - 0.0000000000000000000000001898 117.0
PYH3_k127_8096265_0 aminotransferase, class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 527.0
PYH3_k127_8096265_1 PFAM Radical SAM K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 411.0
PYH3_k127_8096265_11 Protein of unknown function (DUF3365) - - - 0.0005507 48.0
PYH3_k127_8096265_2 Calcineurin-like phosphoesterase K07313 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000002038 257.0
PYH3_k127_8096265_3 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001554 245.0
PYH3_k127_8096265_4 S-layer homology domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002102 236.0
PYH3_k127_8096265_5 DNA photolyase activity K03716 - 4.1.99.14 0.00000000000000000000000000000000000000000000000000000004567 211.0
PYH3_k127_8096265_6 Thiamine-binding protein - - - 0.00000000000000000000000000000000001966 138.0
PYH3_k127_8096265_7 GDP-mannose 4,6 dehydratase K01784,K08678 - 4.1.1.35,5.1.3.2 0.0000000000000000000000000009593 115.0
PYH3_k127_8096265_8 SMART Water Stress and Hypersensitive response - - - 0.0000000000000000000000004361 110.0
PYH3_k127_8119078_0 heat shock protein DnaJ domain protein K03686,K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 320.0
PYH3_k127_8119078_1 Protein of unknown function (DUF434) - - - 0.0000000000000000000000000000000000000000000001329 175.0
PYH3_k127_8119078_2 Alpha beta hydrolase - - - 0.00000000000000000000000002442 113.0
PYH3_k127_8126544_0 Phosphate acyltransferases K03928 - 3.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 559.0
PYH3_k127_8126544_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006311 270.0
PYH3_k127_8126544_2 Belongs to the enoyl-CoA hydratase isomerase family K01715,K13766 - 4.2.1.17,4.2.1.18 0.000000000000000000000000000000000000000000000000000000000000000000001428 245.0
PYH3_k127_8126544_3 Receptor family ligand binding region - - - 0.00000000000000000000000000000000000000000000000000004941 193.0
PYH3_k127_8126544_4 membrane K08978 - - 0.0000000000000000000000000000000000000000001519 162.0
PYH3_k127_8126544_5 Tetratricopeptide repeat - - - 0.00001286 54.0
PYH3_k127_814534_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 478.0
PYH3_k127_8151222_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009406 347.0
PYH3_k127_8151222_1 PFAM RimK domain protein ATP-grasp K05844 - - 0.000000000000000000000000000000000000000000000000000000000000000001522 235.0
PYH3_k127_8151222_2 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000002192 226.0
PYH3_k127_815178_0 Major facilitator Superfamily K03292 - - 4.515e-196 622.0
PYH3_k127_815178_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 422.0
PYH3_k127_815178_2 3-oxo-5-alpha-steroid 4-dehydrogenase K12343 - 1.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 372.0
PYH3_k127_822784_0 Belongs to the 'phage' integrase family - - - 0.0000000000001699 79.0
PYH3_k127_822784_1 - - - - 0.000009181 51.0
PYH3_k127_822784_2 Belongs to the 'phage' integrase family - - - 0.00009733 46.0
PYH3_k127_825891_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007599 392.0
PYH3_k127_825891_1 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009097 267.0
PYH3_k127_825891_2 Transglycosylase SLT domain K08305 - - 0.00000000000000000000000000000000000000000000000000001221 204.0
PYH3_k127_825891_3 low molecular weight K01104,K20201 - 3.1.3.48,3.9.1.2 0.0000000000000000000000000000003277 128.0
PYH3_k127_825891_4 PFAM YbaK prolyl-tRNA synthetases associated domain - - - 0.0000000000000000000000000000007886 128.0
PYH3_k127_825891_5 Histone deacetylase domain K04768 - - 0.0000000000000000000003154 98.0
PYH3_k127_8338780_0 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 587.0
PYH3_k127_8338780_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003388 485.0
PYH3_k127_8338780_2 Pterin binding enzyme K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 396.0
PYH3_k127_8344428_0 TIGRFAM glutamine synthetase, type I K01915 - 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 467.0
PYH3_k127_8344428_1 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 371.0
PYH3_k127_8344428_2 AIR carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 305.0
PYH3_k127_8344428_3 PFAM Three-deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 296.0
PYH3_k127_8344428_4 PFAM thioesterase superfamily protein K07107 - - 0.00000000000000000000000003438 117.0
PYH3_k127_8344428_5 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.0000000000000000000008859 99.0
PYH3_k127_8344428_6 B12 binding domain - - - 0.000000000000000002475 92.0
PYH3_k127_8345666_0 cyclopropane-fatty-acyl-phospholipid synthase K00574,K20238 - 2.1.1.317,2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 564.0
PYH3_k127_8345666_1 Membrane - - - 0.000000000000000000000000000000000000000000000567 169.0
PYH3_k127_8345666_2 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000001203 151.0
PYH3_k127_8345666_3 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.0000000000000000000000000000000000002425 142.0
PYH3_k127_8345666_4 lipid a biosynthesis K02517 - 2.3.1.241 0.0001025 46.0
PYH3_k127_8357356_0 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000004864 232.0
PYH3_k127_8357356_1 - - - - 0.0000000000000000000000000000000000000000000000002458 181.0
PYH3_k127_8357356_2 TIGRFAM phosphoesterase, MJ0936 family K07095 - - 0.000000000000000000000000000000000000000000000000313 183.0
PYH3_k127_8357356_3 HI0933-like protein K07007 - - 0.0000000000000000000000000000000000000000008044 159.0
PYH3_k127_8357356_4 Protein of Unknown function (DUF2784) - - - 0.0000000000000000000000000000000000001392 146.0
PYH3_k127_8357356_5 Histidine kinase K11383 - 2.7.13.3 0.0000000000000000000000000000000000006662 140.0
PYH3_k127_8369946_0 PFAM SPFH domain Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003029 312.0
PYH3_k127_8369946_1 Psort location Cytoplasmic, score - - - 0.00000000003804 74.0
PYH3_k127_8378867_0 secondary active sulfate transmembrane transporter activity K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004191 528.0
PYH3_k127_8422275_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.277e-203 642.0
PYH3_k127_8422275_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 422.0
PYH3_k127_8422275_2 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000004201 254.0
PYH3_k127_8422275_3 Belongs to the 'phage' integrase family K03733,K04763 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000002836 112.0
PYH3_k127_8484495_0 PFAM Integrase core domain - - - 0.00000000000000005071 94.0
PYH3_k127_8486529_0 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00124,K00335,K00355,K18331 - 1.12.1.3,1.6.5.2,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 313.0
PYH3_k127_8486529_1 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001679 187.0
PYH3_k127_8491682_0 pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 319.0
PYH3_k127_8491682_1 PFAM Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000000002757 270.0
PYH3_k127_8491682_2 LmbE homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005034 251.0
PYH3_k127_8491682_3 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000007562 161.0
PYH3_k127_8491682_4 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000002081 127.0
PYH3_k127_850245_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002763 512.0
PYH3_k127_850245_1 PFAM AMP-dependent synthetase and ligase K01912 - 6.2.1.30 0.00000000000000002659 88.0
PYH3_k127_850245_2 Protein of unknown function DUF89 - - - 0.00000000000001491 79.0
PYH3_k127_8511087_0 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 551.0
PYH3_k127_8523394_0 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000005115 226.0
PYH3_k127_8523394_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000001891 218.0
PYH3_k127_8523394_2 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000001867 177.0
PYH3_k127_8587578_0 Pyridoxal-phosphate dependent enzyme K01738,K01883,K12339 - 2.5.1.47,6.1.1.16 9.005e-210 666.0
PYH3_k127_8587578_1 TIGRFAM threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 466.0
PYH3_k127_8587578_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000002686 230.0
PYH3_k127_8617488_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 615.0
PYH3_k127_8617488_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 293.0
PYH3_k127_8617488_2 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000006575 133.0
PYH3_k127_8617488_3 PFAM nitrogen-fixing NifU - - - 0.00000000000000000000000002946 109.0
PYH3_k127_8617488_4 Exopolysaccharide biosynthesis protein YbjH - - - 0.00000001029 61.0
PYH3_k127_8619052_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 1.939e-203 660.0
PYH3_k127_8619052_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001343 275.0
PYH3_k127_8643348_0 Biotin-protein ligase, N terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005922 310.0
PYH3_k127_8643348_1 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001011 266.0
PYH3_k127_8643348_2 Belongs to the bacterial histone-like protein family K05788 - - 0.0000000000000000000000000000000103 131.0
PYH3_k127_8643348_3 - - - - 0.0000000000000000002062 89.0
PYH3_k127_8649975_0 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1021.0
PYH3_k127_8649975_1 4Fe-4S dicluster domain K16887 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 355.0
PYH3_k127_8649975_2 binding domain K16885 - - 0.00000000000000000000000000000000000000000000000000000000000000000003945 235.0
PYH3_k127_8656120_0 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003622 447.0
PYH3_k127_8656120_2 Phosphonate ABC transporter, periplasmic K02044 - - 0.0000000000000000000000000000000000000001153 154.0
PYH3_k127_8656120_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000001722 79.0
PYH3_k127_8690818_0 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000007254 146.0
PYH3_k127_8690818_1 Domain of unknown function (DUF4388) - - - 0.000000000000003438 84.0
PYH3_k127_8691206_0 ABC-Type Dipeptide Transport System Periplasmic Component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 597.0
PYH3_k127_8691206_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009822 302.0
PYH3_k127_8691206_2 nitrogen compound transport K02033,K13894 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001732 260.0
PYH3_k127_8691206_3 Transposase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004255 255.0
PYH3_k127_8695363_0 PFAM nitrite and sulphite reductase 4Fe-4S K11180 - 1.8.99.5 1.153e-240 747.0
PYH3_k127_8695363_1 TIGRFAM sulfite reductase, dissimilatory-type beta subunit K11181 - 1.8.99.5 4.031e-200 627.0
PYH3_k127_8695363_2 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007108 609.0
PYH3_k127_8695363_3 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 548.0
PYH3_k127_8695363_4 FCD K05799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003763 292.0
PYH3_k127_8695363_5 TIGRFAM sulfur relay protein, TusE DsrC DsvC family K11179 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000001527 195.0
PYH3_k127_8695363_6 - - - - 0.0000000000000000000000000000000002359 134.0
PYH3_k127_8695363_7 PFAM Dissimilatory sulfite reductase D - - - 0.000000000000000000000000000001836 122.0
PYH3_k127_8699937_0 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000001438 168.0
PYH3_k127_8699937_1 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000000000007869 141.0
PYH3_k127_8699937_2 - - - - 0.0000000000000000000000000000002912 126.0
PYH3_k127_8700389_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.43e-322 1004.0
PYH3_k127_8756875_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 413.0
PYH3_k127_8756875_1 Permease family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008038 389.0
PYH3_k127_8756875_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 GO:0003674,GO:0003824,GO:0004595,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000005922 234.0
PYH3_k127_8756875_3 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000001653 198.0
PYH3_k127_8756875_4 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.0000000000000000000000000000000002621 137.0
PYH3_k127_8756875_5 Thioredoxin-like - - - 0.00000000000000002132 93.0
PYH3_k127_8764833_0 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003373 260.0
PYH3_k127_8764833_1 Binding-protein-dependent transport system inner membrane component K02025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003403 259.0
PYH3_k127_8764833_2 Bacterial extracellular solute-binding protein K02027 - - 0.0000000000000000000000000000000000000000000000000000003262 209.0
PYH3_k127_8776597_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 4.877e-240 752.0
PYH3_k127_8776597_1 competence protein ComEA helix-hairpin-helix repeat protein K02237 - - 0.0005125 49.0
PYH3_k127_8789671_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 458.0
PYH3_k127_8789671_1 DHH family K07462 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 355.0
PYH3_k127_8789671_2 PFAM transglutaminase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005147 294.0
PYH3_k127_8789671_3 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002427 275.0
PYH3_k127_8789671_4 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000008033 228.0
PYH3_k127_8799221_0 DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000006002 242.0
PYH3_k127_8799221_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000006802 210.0
PYH3_k127_8799221_2 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.00000000000000000000001664 103.0
PYH3_k127_8807860_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 3.526e-214 672.0
PYH3_k127_8807860_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 333.0
PYH3_k127_8807860_2 Bacterial trigger factor protein (TF) C-terminus K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005512 297.0
PYH3_k127_8807860_3 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000000000000006478 101.0
PYH3_k127_8807860_4 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 0.0000004342 53.0
PYH3_k127_8825764_0 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
PYH3_k127_8825764_1 Cupin - - - 0.00000000002107 73.0
PYH3_k127_8825764_2 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000007668 58.0
PYH3_k127_8829066_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 1.993e-284 890.0
PYH3_k127_8829066_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 511.0
PYH3_k127_8829066_2 Belongs to the bacterial histone-like protein family K05788 - - 0.000000000000000000000000000002652 124.0
PYH3_k127_8829066_3 Sporulation and spore germination - - - 0.0000000000000000000000001216 114.0
PYH3_k127_8829066_4 production of miRNAs involved in gene silencing by miRNA K04459,K13108,K21278 GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0006139,GO:0006396,GO:0006397,GO:0006403,GO:0006405,GO:0006406,GO:0006611,GO:0006725,GO:0006807,GO:0006810,GO:0006886,GO:0006913,GO:0008104,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0015031,GO:0015833,GO:0015931,GO:0016070,GO:0016071,GO:0031503,GO:0032991,GO:0033036,GO:0034613,GO:0034641,GO:0042886,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045184,GO:0046483,GO:0046907,GO:0050657,GO:0050658,GO:0051028,GO:0051168,GO:0051169,GO:0051179,GO:0051234,GO:0051235,GO:0051236,GO:0051237,GO:0051641,GO:0051649,GO:0065007,GO:0065008,GO:0070274,GO:0070727,GO:0071166,GO:0071426,GO:0071427,GO:0071702,GO:0071704,GO:0071705,GO:0090304,GO:0097159,GO:1901360,GO:1901363 3.1.3.16,3.1.3.48 0.00000003493 64.0
PYH3_k127_8829066_5 Integral membrane protein CcmA involved in cell shape determination - - - 0.000002909 51.0
PYH3_k127_8838154_0 Uncharacterized protein conserved in bacteria (DUF2344) - - - 1.654e-233 749.0
PYH3_k127_8838154_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 2.572e-199 633.0
PYH3_k127_8838154_2 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000003171 138.0
PYH3_k127_8838154_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000001146 127.0
PYH3_k127_8838154_4 - - - - 0.00000000000000000002316 93.0
PYH3_k127_8838154_5 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006996,GO:0007059,GO:0008150,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0022607,GO:0022611,GO:0022613,GO:0022618,GO:0032502,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034622,GO:0035639,GO:0036094,GO:0042254,GO:0042255,GO:0043021,GO:0043023,GO:0043167,GO:0043168,GO:0043933,GO:0044085,GO:0044087,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0065003,GO:0065007,GO:0070925,GO:0071826,GO:0071840,GO:0090069,GO:0090071,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000001685 82.0
PYH3_k127_8838154_6 DNA polymerase A domain K02335 - 2.7.7.7 0.000000000000002971 76.0
PYH3_k127_8838154_7 Transposase K07483 - - 0.0005899 51.0
PYH3_k127_8842112_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.731e-289 916.0
PYH3_k127_8842112_1 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 2.789e-276 866.0
PYH3_k127_8842112_10 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.000000000000000000000000000000000000000000000002334 179.0
PYH3_k127_8842112_11 - - - - 0.000000000000000000000000000000000000000000007548 170.0
PYH3_k127_8842112_12 Required for maturation of 30S ribosomal subunits K09748 - - 0.00000000000000000000000000000000001078 141.0
PYH3_k127_8842112_13 Ribosomal_S15 K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000003956 136.0
PYH3_k127_8842112_14 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000007393 121.0
PYH3_k127_8842112_15 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000009254 103.0
PYH3_k127_8842112_16 - - - - 0.00000000000000000000429 97.0
PYH3_k127_8842112_17 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000278 96.0
PYH3_k127_8842112_18 Protein of unknown function (DUF448) - - - 0.000000000003095 73.0
PYH3_k127_8842112_19 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000002025 60.0
PYH3_k127_8842112_2 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 564.0
PYH3_k127_8842112_21 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0001643 45.0
PYH3_k127_8842112_3 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003541 515.0
PYH3_k127_8842112_4 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006132 511.0
PYH3_k127_8842112_5 PFAM Peptidase M16 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 486.0
PYH3_k127_8842112_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 373.0
PYH3_k127_8842112_7 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009668 263.0
PYH3_k127_8842112_8 DHH family K06881 - 3.1.13.3,3.1.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000002717 261.0
PYH3_k127_8842112_9 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016556,GO:0016853,GO:0016866,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1990481 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000001609 221.0
PYH3_k127_8937273_0 transport system involved in gliding motility auxiliary component-like K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008624 410.0
PYH3_k127_8937273_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002975 382.0
PYH3_k127_8937273_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002707 286.0
PYH3_k127_8937273_3 Serine aminopeptidase, S33 K06889 - - 0.00000000000000000000000000000000000000000000000000000000000002359 224.0
PYH3_k127_8937273_4 Histidine kinase - - - 0.000000000000000000000000000000001144 134.0
PYH3_k127_8937273_5 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.0000000000000000000002307 100.0
PYH3_k127_8937273_6 - - - - 0.000000000000000004397 86.0
PYH3_k127_8937273_7 Domain of unknown function (DUF4340) - - - 0.00000000000001162 87.0
PYH3_k127_8938270_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 4.221e-218 690.0
PYH3_k127_8938270_1 response regulator - - - 0.0000000000000000000000000000000000000000000000000000000002742 205.0
PYH3_k127_8938270_2 Histidine kinase - - - 0.00000000005845 66.0
PYH3_k127_8938270_3 Histidine kinase - - - 0.0000000003932 62.0
PYH3_k127_8960069_0 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 553.0
PYH3_k127_8960069_1 Cupin domain K11312 - - 0.0000000000000000000000000000000000003384 147.0
PYH3_k127_8960069_2 4Fe-4S binding domain - - - 0.000000005344 57.0
PYH3_k127_8965356_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.842e-277 870.0
PYH3_k127_8965356_1 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000296 78.0
PYH3_k127_8991539_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.371e-320 998.0
PYH3_k127_8991539_1 CO dehydrogenase/acetyl-CoA synthase delta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 344.0
PYH3_k127_8991539_2 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007414 291.0
PYH3_k127_8991539_3 Archaea-specific editing domain of threonyl-tRNA synthetase - - - 0.00000000000000000000000000000000000000000000002413 173.0
PYH3_k127_8991539_4 4Fe-4S binding domain - - - 0.000000000000000000000000007666 113.0
PYH3_k127_8991539_5 Heavy-metal-associated domain - - - 0.000000000000000000000002427 103.0
PYH3_k127_8991539_6 Putative diguanylate phosphodiesterase - - - 0.00000000000000004585 94.0
PYH3_k127_8991539_7 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000002177 80.0
PYH3_k127_8995816_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 5.98e-319 979.0
PYH3_k127_8995816_1 COG1132 ABC-type multidrug transport system, ATPase and permease components K11085 GO:0003674,GO:0003824,GO:0005215,GO:0005319,GO:0006810,GO:0006869,GO:0008150,GO:0010876,GO:0015399,GO:0015405,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022857,GO:0033036,GO:0034040,GO:0042623,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0071702 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005532 422.0
PYH3_k127_8995816_2 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 296.0
PYH3_k127_8995816_3 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.000000000000000000000000000000000000000000000000000000000000000000000000008013 256.0
PYH3_k127_8995816_4 Ferric uptake regulator family K09825 - - 0.00000000000000000000000000000000000000000000000000001195 192.0
PYH3_k127_8995816_5 YCII-related domain - - - 0.0000000000000000000000001516 108.0
PYH3_k127_8995816_6 Catalase K03781 - 1.11.1.6 0.000007225 49.0
PYH3_k127_8996430_0 Appr-1'-p processing enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000002273 230.0
PYH3_k127_8996430_1 PFAM Yip1 domain - - - 0.000000000000000002895 91.0
PYH3_k127_9008805_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006335 567.0
PYH3_k127_9008805_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 572.0
PYH3_k127_9008805_10 PFAM Radical SAM superfamily - - - 0.000000003016 68.0
PYH3_k127_9008805_11 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000191 60.0
PYH3_k127_9008805_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 370.0
PYH3_k127_9008805_3 PFAM Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 365.0
PYH3_k127_9008805_4 ResB-like family K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 368.0
PYH3_k127_9008805_5 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000007781 227.0
PYH3_k127_9008805_6 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000003172 115.0
PYH3_k127_9008805_7 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000001069 118.0
PYH3_k127_9008805_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000243 111.0
PYH3_k127_9008805_9 Fe-S oxidoreductase K04034 - 1.21.98.3 0.00000000000007161 76.0
PYH3_k127_9010224_0 Conserved region in glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 601.0
PYH3_k127_9010224_1 ANTAR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003353 283.0
PYH3_k127_9010224_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001307 272.0
PYH3_k127_9010224_3 Type IV pilus assembly protein PilM; K02662 - - 0.0003507 45.0
PYH3_k127_9015733_0 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0 1096.0
PYH3_k127_9015733_1 gluconolactonase activity K01053 - 3.1.1.17 5.669e-204 649.0
PYH3_k127_9015733_2 PFAM GMC oxidoreductase - - - 1.25e-201 639.0
PYH3_k127_9015733_3 gluconolactonase K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007816 434.0
PYH3_k127_9015733_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000516 432.0
PYH3_k127_9015733_5 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 355.0
PYH3_k127_9015733_6 Cupin 2, conserved barrel domain protein K11477 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 304.0
PYH3_k127_9015733_7 Haem-degrading - - - 0.00000000000000000000000000000000000005194 148.0
PYH3_k127_9015733_8 alcohol dehydrogenase - - - 0.00000000003298 64.0
PYH3_k127_9033714_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005534 514.0
PYH3_k127_9033714_1 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 326.0
PYH3_k127_9033714_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000001689 265.0
PYH3_k127_9033714_3 acetyl-CoA catabolic process K00197,K03616 - 2.1.1.245 0.0000000000000000001517 98.0
PYH3_k127_9033714_4 metal cluster binding K06940,K18475 - - 0.000000000004019 76.0
PYH3_k127_9033714_5 Putative transmembrane protein (PGPGW) - - - 0.00000008695 57.0
PYH3_k127_9033714_6 Putative regulatory protein - - - 0.0000003824 52.0
PYH3_k127_9034657_0 Belongs to the DEAD box helicase family K03732 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002612 474.0
PYH3_k127_9034657_1 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003724 253.0
PYH3_k127_9034657_2 ATP adenylyltransferase K00988 - 2.7.7.53 0.00000000000000000000000000000000000000000000002656 175.0
PYH3_k127_9041042_0 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000995 520.0
PYH3_k127_9041042_1 integrase domain protein SAM domain protein K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004208 320.0
PYH3_k127_9041042_2 PFAM phosphoesterase, RecJ domain protein - - - 0.000000000000000000000000000004307 124.0
PYH3_k127_9052772_0 antitermination protein NusG K05785 - - 0.000000000000000000000000000000000000000000000000001298 190.0
PYH3_k127_9052772_1 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000001204 62.0
PYH3_k127_9052772_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0003194 52.0
PYH3_k127_906358_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000003865 138.0
PYH3_k127_906358_1 - - - - 0.000000000000000000000000000000199 132.0
PYH3_k127_9066591_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 3.716e-240 754.0
PYH3_k127_90733_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004126 449.0
PYH3_k127_90733_1 ACT domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001684 223.0
PYH3_k127_9074725_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 409.0
PYH3_k127_9074725_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000004435 75.0
PYH3_k127_9076856_0 Transglycosylase K05366,K21464 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 614.0
PYH3_k127_9076856_1 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 425.0
PYH3_k127_9076856_10 DUF218 domain - - - 0.000005261 52.0
PYH3_k127_9076856_2 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 294.0
PYH3_k127_9076856_3 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000001015 273.0
PYH3_k127_9076856_4 DJ-1/PfpI family K03152,K05520,K05687,K12132 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006464,GO:0006517,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009100,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0019538,GO:0022613,GO:0030091,GO:0033554,GO:0034599,GO:0036211,GO:0036524,GO:0036525,GO:0042026,GO:0042221,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051716,GO:0070887,GO:0071704,GO:0071840,GO:0140096,GO:1901135,GO:1901564 2.7.11.1,3.5.1.124 0.000000000000000000000000000000000000000000000000000000000000000000000000001201 260.0
PYH3_k127_9076856_5 Trypsin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001055 259.0
PYH3_k127_9076856_6 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840,K15778 - 5.4.2.2,5.4.2.8 0.0000000000000000000000000000002815 125.0
PYH3_k127_9076856_7 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000007641 127.0
PYH3_k127_9076856_8 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000648 78.0
PYH3_k127_9076856_9 Protein of unknown function (DUF1285) K09986 - - 0.00000000000132 76.0
PYH3_k127_9088092_0 His Kinase A (phosphoacceptor) domain K10819 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000987 511.0
PYH3_k127_9088092_1 PFAM Extracellular ligand-binding receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004336 495.0
PYH3_k127_9088092_2 Periplasmic binding protein domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 321.0
PYH3_k127_9088092_3 response regulator, receiver - - - 0.0000000000000005499 79.0
PYH3_k127_9089904_0 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006632 360.0
PYH3_k127_9089904_1 PFAM aminotransferase, class IV K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000328 331.0
PYH3_k127_9089904_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000005222 211.0
PYH3_k127_9089904_3 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000004395 148.0
PYH3_k127_9089904_4 Putative regulatory protein - - - 0.000000000000003382 76.0
PYH3_k127_9091565_0 extracellular solute-binding protein, family 5 - - - 3.434e-254 790.0
PYH3_k127_9091565_1 Saccharopine dehydrogenase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000867 497.0
PYH3_k127_9091565_2 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369,K13890 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 459.0
PYH3_k127_9091565_3 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
PYH3_k127_9091565_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000868 441.0
PYH3_k127_9091565_5 Dihydrodipicolinate reductase, N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004373 420.0
PYH3_k127_9091565_6 Belongs to the ABC transporter superfamily K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 414.0
PYH3_k127_9097746_0 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000125 252.0
PYH3_k127_9097746_1 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000000000000000000000001088 225.0
PYH3_k127_9097746_3 PFAM Integral membrane protein TerC - - - 0.0000000000000000001141 89.0
PYH3_k127_9097746_4 membrane protein TerC - - - 0.00000007649 60.0
PYH3_k127_9097746_5 positive regulation of growth - GO:0008150,GO:0040008,GO:0045927,GO:0048518,GO:0050789,GO:0065007 - 0.0000008334 55.0
PYH3_k127_9097746_6 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00001808 52.0
PYH3_k127_909856_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic K00058 - 1.1.1.399,1.1.1.95 2.386e-228 718.0
PYH3_k127_909856_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000401 223.0
PYH3_k127_909856_2 Domain of unknown function (DUF1844) - - - 0.000000000000000000000000000000002421 133.0
PYH3_k127_909856_3 - - - - 0.000000000000000000001032 104.0
PYH3_k127_9119260_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 528.0
PYH3_k127_9119260_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003451 411.0
PYH3_k127_9119260_2 Major Facilitator Superfamily K08177 - - 0.0000000000000000000000000000000000000000000423 162.0
PYH3_k127_9119260_3 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000004229 164.0
PYH3_k127_9119260_4 Branched-chain amino acid ATP-binding cassette transporter K01995,K01998 - - 0.000000000000000000000000000000000004917 148.0
PYH3_k127_9119260_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000003746 142.0
PYH3_k127_9119260_7 - - - - 0.000000000000000000000003828 111.0
PYH3_k127_9119260_8 metal cluster binding K06940,K18475 - - 0.00003018 54.0
PYH3_k127_9138777_0 Glycoside hydrolase family 3 domain protein K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000002352 254.0
PYH3_k127_9138777_1 Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000001096 231.0
PYH3_k127_9138777_2 Nucleotidyl transferase - - - 0.000000000000000000000000000000000000000000000000000000013 211.0
PYH3_k127_9138777_3 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000002568 106.0
PYH3_k127_9181548_0 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000048 217.0
PYH3_k127_9181548_1 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000263 64.0
PYH3_k127_9186216_0 Sigma factor PP2C-like phosphatases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 437.0
PYH3_k127_9233707_0 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 6.741e-310 992.0
PYH3_k127_9233707_1 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000001808 252.0
PYH3_k127_9233707_2 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000001274 209.0
PYH3_k127_9275173_0 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000009879 205.0
PYH3_k127_9275173_1 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.000000000000000000000000000000000000000000000003157 177.0
PYH3_k127_9288910_0 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 464.0
PYH3_k127_9288910_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 300.0
PYH3_k127_9288910_2 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.000000002845 59.0
PYH3_k127_929468_0 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004677 480.0
PYH3_k127_929468_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 413.0
PYH3_k127_9318635_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007756 416.0
PYH3_k127_9318635_1 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 398.0
PYH3_k127_9318635_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000002449 220.0
PYH3_k127_9318635_3 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000009551 126.0
PYH3_k127_9321754_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 446.0
PYH3_k127_9321754_1 Gaf domain K13590,K21084 - 2.7.7.65 0.0000000000000000005803 100.0
PYH3_k127_9355884_0 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003175 305.0
PYH3_k127_9355884_1 Belongs to the LOG family K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000008875 215.0
PYH3_k127_9376456_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008199 606.0
PYH3_k127_9376456_1 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004152 269.0
PYH3_k127_9376456_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000201 141.0
PYH3_k127_9376456_3 FAD dependent oxidoreductase - - - 0.00000000000000000000002306 99.0
PYH3_k127_9376456_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.00000000000000001446 83.0
PYH3_k127_9394083_0 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 4.929e-292 905.0
PYH3_k127_9394083_1 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 350.0
PYH3_k127_9394083_2 PFAM ABC transporter related K01995 - - 0.0000000000000000000002693 97.0
PYH3_k127_9414151_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 1.577e-204 679.0
PYH3_k127_9414151_1 MASE1 - - - 0.00004851 50.0
PYH3_k127_94197_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.25e-252 786.0
PYH3_k127_94197_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 372.0
PYH3_k127_94197_2 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000002626 216.0
PYH3_k127_94197_3 Saccharopine dehydrogenase C-terminal domain - - - 0.00001025 51.0
PYH3_k127_9465432_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000006895 214.0
PYH3_k127_9465432_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.0000000000000000000000000000000000000000000117 168.0
PYH3_k127_9465432_2 protein conserved in bacteria (DUF2062) K09928 - - 0.0000000000000000000000000002815 120.0
PYH3_k127_9465432_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000001663 100.0
PYH3_k127_9465432_4 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000004734 52.0
PYH3_k127_9474180_0 Mechanosensitive ion channel K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 500.0
PYH3_k127_9511344_0 PFAM major facilitator superfamily MFS_1 K03446 - - 8.046e-231 725.0
PYH3_k127_9511344_1 PFAM secretion protein HlyD K03543 - - 0.000000000000000000000000000000000000000000000000000000000002129 217.0
PYH3_k127_9511344_2 - - - - 0.0000000000000000000001058 102.0
PYH3_k127_9593724_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004996 480.0
PYH3_k127_9593724_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003453 293.0
PYH3_k127_9593724_2 TIGRFAM siroheme synthase K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000002816 205.0
PYH3_k127_9593724_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000001888 172.0
PYH3_k127_9593724_4 - - - - 0.0000000000000000000000000000006386 126.0
PYH3_k127_9593724_5 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000005534 86.0
PYH3_k127_9593724_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.00000000000001888 76.0
PYH3_k127_96083_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 594.0
PYH3_k127_96083_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000003008 209.0
PYH3_k127_9646967_0 3-dehydroquinate synthase (EC 4.6.1.3) K11646 - 1.4.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 386.0
PYH3_k127_9646967_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000004079 235.0
PYH3_k127_9681304_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 471.0
PYH3_k127_9681304_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 301.0
PYH3_k127_9681304_2 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000000001262 229.0
PYH3_k127_969801_0 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009498 270.0
PYH3_k127_969801_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000002858 164.0
PYH3_k127_9708179_0 Domain of unknown function (DUF1992) - - - 0.000000000000000000000000000000000000000000003279 168.0
PYH3_k127_9708179_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000003549 122.0
PYH3_k127_9708179_2 HD domain - - - 0.000000000000000000000000002319 113.0
PYH3_k127_9708179_3 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.0000000000000000000003014 99.0
PYH3_k127_9742695_0 B-1 B cell differentiation - - - 1.042e-281 896.0
PYH3_k127_9750082_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1035.0
PYH3_k127_9750082_1 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 GO:0003674,GO:0003824,GO:0004042,GO:0004358,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006592,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.1,2.3.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009527 397.0
PYH3_k127_9750082_2 Fis Family K02584 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 362.0
PYH3_k127_9750082_3 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000006366 193.0
PYH3_k127_9750082_4 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000004394 178.0
PYH3_k127_9750082_5 Polymer-forming cytoskeletal - - - 0.00000000000000000000000002036 113.0
PYH3_k127_9750082_6 Initiation factor 2 subunit family K03680 - - 0.0000000000000000000001205 106.0
PYH3_k127_9759261_0 Zinc-binding dehydrogenase K12957 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000259 392.0
PYH3_k127_9759261_1 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.0000000000000000000000000000000000001334 146.0
PYH3_k127_9759261_2 Outer membrane lipoprotein Slp family K07285 - - 0.000000000000000000000000000000005262 140.0
PYH3_k127_9759261_3 Outer membrane lipoprotein Slp family K07285 - - 0.0000000000000000000000000001298 122.0
PYH3_k127_9777907_0 type II secretion system K02454 - - 9.189e-210 666.0
PYH3_k127_9777907_1 ABC-type uncharacterized transport system - - - 0.000000000001613 80.0
PYH3_k127_9777907_2 domain protein - - - 0.00001387 57.0
PYH3_k127_97855_0 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 6.247e-225 706.0
PYH3_k127_97855_1 pfam abc K02028 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 408.0
PYH3_k127_97855_2 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 336.0
PYH3_k127_97855_3 PFAM Extracellular solute-binding protein, family 3 K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008352 322.0
PYH3_k127_97855_4 PFAM binding-protein-dependent transport systems inner membrane component K02029 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006615 316.0
PYH3_k127_97855_5 DsrE/DsrF/DrsH-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002809 247.0
PYH3_k127_97855_6 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.00000001854 57.0
PYH3_k127_9788745_0 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 357.0
PYH3_k127_9788745_1 PFAM ThiJ PfpI domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008017 317.0
PYH3_k127_9788745_2 PFAM Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000445 258.0
PYH3_k127_9788745_3 Belongs to the rubredoxin family - GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0006091,GO:0008150,GO:0008152,GO:0008199,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0055114 - 0.0000000000000000000000000000000595 125.0
PYH3_k127_9788745_4 - - - - 0.000000000000000000000364 101.0
PYH3_k127_9788745_5 - - - - 0.0000000000000002168 81.0
PYH3_k127_9788745_6 - - - - 0.00000000001504 66.0
PYH3_k127_9788745_7 - - - - 0.0000000001803 62.0