Overview

ID MAG03214
Name PYH3_bin.16
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum BMS3Abin14
Class BMS3Abin14
Order BMS3Abin14
Family
Genus
Species
Assembly information
Completeness (%) 99.94
Contamination (%) 2.11
GC content (%) 66.0
N50 (bp) 16,128
Genome size (bp) 2,193,304

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2001

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1104510_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 8.275e-202 637.0
PYH3_k127_1104510_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 387.0
PYH3_k127_1104510_10 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000001401 193.0
PYH3_k127_1104510_11 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000003738 192.0
PYH3_k127_1104510_12 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000005954 177.0
PYH3_k127_1104510_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000007442 171.0
PYH3_k127_1104510_14 PFAM ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000008362 164.0
PYH3_k127_1104510_15 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000002266 156.0
PYH3_k127_1104510_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000001507 144.0
PYH3_k127_1104510_17 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000001958 131.0
PYH3_k127_1104510_18 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005591 104.0
PYH3_k127_1104510_19 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.000000000000000000000001536 109.0
PYH3_k127_1104510_2 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003695 295.0
PYH3_k127_1104510_20 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000001785 70.0
PYH3_k127_1104510_21 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000001058 75.0
PYH3_k127_1104510_22 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000001928 71.0
PYH3_k127_1104510_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 291.0
PYH3_k127_1104510_4 TIGRFAM methionine aminopeptidase, type I K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006003 292.0
PYH3_k127_1104510_5 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001037 274.0
PYH3_k127_1104510_6 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000003889 237.0
PYH3_k127_1104510_7 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.000000000000000000000000000000000000000000000000000000000000009625 217.0
PYH3_k127_1104510_8 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000007702 211.0
PYH3_k127_1104510_9 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000002551 201.0
PYH3_k127_1212090_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 566.0
PYH3_k127_1212090_1 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791 - 5.1.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006432 392.0
PYH3_k127_1212090_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009421 308.0
PYH3_k127_1212090_3 TIGRFAM lipopolysaccharide heptosyltransferase II K02843 - - 0.000000000000000000000000000000000000000000000000000000004181 224.0
PYH3_k127_1212090_4 heptosyltransferase K02841 - - 0.000000000000000000000000000000000000000000000000006127 194.0
PYH3_k127_1212090_5 Phospholipid methyltransferase - - - 0.00000000000000000000000001085 117.0
PYH3_k127_1212090_6 Protein of unknown function (DUF3108) - - - 0.0000344 48.0
PYH3_k127_1241657_0 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 541.0
PYH3_k127_1241657_1 Proposed homoserine kinase K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005174 442.0
PYH3_k127_1241657_2 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005426 413.0
PYH3_k127_1241657_3 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005886 407.0
PYH3_k127_1241657_4 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000001063 71.0
PYH3_k127_1254623_0 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000494 383.0
PYH3_k127_1254623_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005798 338.0
PYH3_k127_1254623_2 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000415 323.0
PYH3_k127_1254623_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 294.0
PYH3_k127_1254623_4 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000001763 267.0
PYH3_k127_1254623_5 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000365 263.0
PYH3_k127_1254623_6 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000002097 230.0
PYH3_k127_1254623_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 GO:0002181,GO:0002184,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006415,GO:0006518,GO:0006807,GO:0008079,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022411,GO:0030312,GO:0032984,GO:0034641,GO:0034645,GO:0040007,GO:0043021,GO:0043023,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000003663 224.0
PYH3_k127_1254623_8 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000005519 210.0
PYH3_k127_1275604_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 576.0
PYH3_k127_1275604_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 541.0
PYH3_k127_1275604_2 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 447.0
PYH3_k127_1275604_3 Histidyl-tRNA synthetase K00765,K01892,K02502 - 2.4.2.17,6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000004095 271.0
PYH3_k127_1275604_4 Putative MetA-pathway of phenol degradation - - - 0.000000007884 65.0
PYH3_k127_1294256_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 356.0
PYH3_k127_1294256_1 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008813 280.0
PYH3_k127_1301638_0 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000056 199.0
PYH3_k127_1301638_1 SMART Tetratricopeptide domain protein - - - 0.000000000000000000000000000000000000000000001775 185.0
PYH3_k127_1301638_2 ABC transporter K02006 - - 0.000000000000000000000000000000005468 128.0
PYH3_k127_1335894_0 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000003439 224.0
PYH3_k127_1335894_1 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000003603 201.0
PYH3_k127_1335894_2 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000000001778 136.0
PYH3_k127_1345183_0 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005591 551.0
PYH3_k127_1345183_1 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 527.0
PYH3_k127_1345183_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 390.0
PYH3_k127_1345183_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 325.0
PYH3_k127_1345183_4 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 307.0
PYH3_k127_1345183_5 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000859 288.0
PYH3_k127_1345183_6 TonB-dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005282 260.0
PYH3_k127_1345183_7 - - - - 0.00000000000000000000000000000000005032 138.0
PYH3_k127_1345183_8 Uncharacterised ArCR, COG2043 - - - 0.0000000000001051 76.0
PYH3_k127_1437415_0 response regulator K07814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 535.0
PYH3_k127_1437415_1 Protein of unknown function DUF116 - - - 0.0000001179 61.0
PYH3_k127_1443112_0 SMART Elongator protein 3 MiaB NifB - - - 1.686e-197 646.0
PYH3_k127_1443112_1 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 317.0
PYH3_k127_1443112_2 PFAM PHP domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005356 274.0
PYH3_k127_1443112_3 protein kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000002337 221.0
PYH3_k127_1443112_4 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000004881 162.0
PYH3_k127_1443112_5 FmdB family - - - 0.00000000000001109 77.0
PYH3_k127_1451866_0 two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003135 520.0
PYH3_k127_1451866_1 PAS domain K13598 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008022 498.0
PYH3_k127_1451866_10 Domain of unknown function (DUF4390) - - - 0.00000000000001148 81.0
PYH3_k127_1451866_11 PFAM metal-dependent phosphohydrolase, HD sub domain K02030 - - 0.0000000000435 76.0
PYH3_k127_1451866_12 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000001223 71.0
PYH3_k127_1451866_2 RnfC Barrel sandwich hybrid domain K03615 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 357.0
PYH3_k127_1451866_3 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001852 295.0
PYH3_k127_1451866_4 Part of a membrane complex involved in electron transport K03614 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007019 291.0
PYH3_k127_1451866_5 UDP-3-O-acyl N-acetylglycosamine deacetylase K02535 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008270,GO:0008610,GO:0008654,GO:0008759,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0019637,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044464,GO:0046467,GO:0046493,GO:0046872,GO:0046914,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001763 282.0
PYH3_k127_1451866_6 TIGRFAM electron transport complex, RnfABCDGE type, B subunit K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004755 275.0
PYH3_k127_1451866_7 Part of a membrane complex involved in electron transport K03613 - - 0.00000000000000000000000000000000000000000000000000000000006101 216.0
PYH3_k127_1451866_8 Rnf-Nqr subunit, membrane protein K03617 - - 0.000000000000000000000000000000000000000000000000000003115 199.0
PYH3_k127_1451866_9 Part of a membrane complex involved in electron transport K03612 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000002564 111.0
PYH3_k127_1452953_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 9.369e-272 863.0
PYH3_k127_1452953_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 381.0
PYH3_k127_1452953_2 PFAM ABC transporter related K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 361.0
PYH3_k127_1452953_3 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004725 257.0
PYH3_k127_1452953_4 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.000000000000000000000000000000000000006344 153.0
PYH3_k127_1474894_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 2.083e-246 777.0
PYH3_k127_1474894_1 Belongs to the KdsA family K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006314 329.0
PYH3_k127_1474894_2 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016301,GO:0016310,GO:0016740,GO:0016757,GO:0016772,GO:0019200,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0046835,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 300.0
PYH3_k127_1474894_3 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000003363 237.0
PYH3_k127_1474894_4 Sulfatase K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000509 247.0
PYH3_k127_1474894_5 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000005168 177.0
PYH3_k127_1507970_0 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004882 606.0
PYH3_k127_1507970_1 response regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 488.0
PYH3_k127_1507970_10 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000005806 104.0
PYH3_k127_1507970_11 PFAM ResB family protein K07399 - - 0.00000002746 56.0
PYH3_k127_1507970_2 Histidine kinase HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 459.0
PYH3_k127_1507970_4 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005046 342.0
PYH3_k127_1507970_5 4Fe-4S binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002359 329.0
PYH3_k127_1507970_6 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 321.0
PYH3_k127_1507970_7 cellulase activity K01181 - 3.2.1.8 0.0000000000000000000000000000000000000000003635 177.0
PYH3_k127_1507970_8 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000002467 169.0
PYH3_k127_1507970_9 Thioredoxin-like - - - 0.0000000000000000000000000000000000000546 157.0
PYH3_k127_1604292_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006023 607.0
PYH3_k127_1604292_1 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 595.0
PYH3_k127_1604292_10 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000003202 201.0
PYH3_k127_1604292_11 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000074 190.0
PYH3_k127_1604292_12 beta-propeller repeat - - - 0.0000000000000000000000000000000000007358 156.0
PYH3_k127_1604292_13 Met-10+ like-protein - - - 0.000000000000000000000000006894 117.0
PYH3_k127_1604292_14 protein kinase related protein - - - 0.000000000000000000000001837 119.0
PYH3_k127_1604292_15 toxin-antitoxin pair type II binding K19159 - - 0.00000000000000001655 86.0
PYH3_k127_1604292_16 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000002213 73.0
PYH3_k127_1604292_17 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000001651 74.0
PYH3_k127_1604292_2 PQQ-like domain K17713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 507.0
PYH3_k127_1604292_3 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 419.0
PYH3_k127_1604292_4 PQQ-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003475 391.0
PYH3_k127_1604292_5 Lysine-2,3-aminomutase K01843 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009013 368.0
PYH3_k127_1604292_6 FMN-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 364.0
PYH3_k127_1604292_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 362.0
PYH3_k127_1604292_8 cation diffusion facilitator family transporter K16264 GO:0000041,GO:0003674,GO:0005215,GO:0005385,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006829,GO:0008150,GO:0008324,GO:0015075,GO:0015318,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0044464,GO:0046873,GO:0046915,GO:0051179,GO:0051234,GO:0055085,GO:0070838,GO:0071577,GO:0071944,GO:0072509,GO:0072511,GO:0098655,GO:0098660,GO:0098662 - 0.000000000000000000000000000000000000000000000000000000000000000000000008423 256.0
PYH3_k127_1604292_9 - K03616 - - 0.00000000000000000000000000000000000000000000000000000000002734 214.0
PYH3_k127_1615217_0 potassium uptake protein TrkH K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 510.0
PYH3_k127_1615217_1 PFAM Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003998 325.0
PYH3_k127_1615217_2 binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002353 276.0
PYH3_k127_1615217_3 PFAM cation transporter K03498 - - 0.000000000000000000000000000000000000000000000000000000000000000000001872 242.0
PYH3_k127_1615217_4 TrkA-N domain K03499 - - 0.0000000000000000000000000000000000000000000000000000002626 201.0
PYH3_k127_1615217_5 domain protein K03499 - - 0.00000000000000000000000000000000000000000000000002191 186.0
PYH3_k127_1615217_6 - - - - 0.000000000000000000002678 102.0
PYH3_k127_175890_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 514.0
PYH3_k127_1787134_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 372.0
PYH3_k127_1787134_1 PFAM UvrB UvrC protein - - - 0.0000000000000000000000000000000000000001285 173.0
PYH3_k127_1787134_11 Photosynthesis system II assembly factor YCF48 - - - 0.00007729 56.0
PYH3_k127_1787134_2 Thioredoxin-like - - - 0.000000000000000000000000000000000000001811 154.0
PYH3_k127_1787134_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000007639 157.0
PYH3_k127_1787134_4 Thioredoxin-like - - - 0.000000000000000000000000000000000181 140.0
PYH3_k127_1787134_6 PFAM glycoside hydrolase, family 13 domain protein - - - 0.000000000000000000000000000001994 130.0
PYH3_k127_1787134_7 NHL repeat - - - 0.0000000000000000000000625 115.0
PYH3_k127_1787134_8 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000003698 76.0
PYH3_k127_1787134_9 GDSL-like Lipase/Acylhydrolase - - - 0.0000000000781 76.0
PYH3_k127_1907427_0 ABC transporter K02017,K06857 - 3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 413.0
PYH3_k127_1907427_1 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001434 396.0
PYH3_k127_1907427_2 PFAM Ketose-bisphosphate aldolase, class-II K01624 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 389.0
PYH3_k127_1907427_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 331.0
PYH3_k127_1907427_4 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009666 258.0
PYH3_k127_1907427_5 LysM domain - - - 0.000000000000000000000000000000000000000000000000000000000009153 213.0
PYH3_k127_1907427_7 Protein of unknown function (DUF1761) - - - 0.0000000009595 64.0
PYH3_k127_1917341_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 1.168e-240 777.0
PYH3_k127_1917341_1 Arginosuccinate synthase K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002276 588.0
PYH3_k127_1917341_10 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 GO:0003674,GO:0003824,GO:0003991,GO:0005488,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016597,GO:0016740,GO:0016772,GO:0016774,GO:0019752,GO:0031406,GO:0034618,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043177,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002531 363.0
PYH3_k127_1917341_11 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003043 313.0
PYH3_k127_1917341_12 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 317.0
PYH3_k127_1917341_13 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611,K09065,K13252 - 2.1.3.3,2.1.3.6,2.1.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 325.0
PYH3_k127_1917341_14 Cobalt transport protein K02008 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 303.0
PYH3_k127_1917341_15 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 294.0
PYH3_k127_1917341_16 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001591 274.0
PYH3_k127_1917341_17 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001509 258.0
PYH3_k127_1917341_18 Belongs to the 'phage' integrase family. XerC subfamily K03733,K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000235 263.0
PYH3_k127_1917341_19 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004346 255.0
PYH3_k127_1917341_2 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007214 541.0
PYH3_k127_1917341_20 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000003644 246.0
PYH3_k127_1917341_21 Helix-turn-helix XRE-family like proteins K21498 - - 0.0000000000000000000000000000000000000001497 152.0
PYH3_k127_1917341_22 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000003859 145.0
PYH3_k127_1917341_23 RelE-like toxin of type II toxin-antitoxin system HigB K07334 - - 0.0000000000000000000000000000001802 126.0
PYH3_k127_1917341_24 PFAM 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK K00950,K13940 - 2.7.6.3,4.1.2.25 0.00000000000000000000000000000563 132.0
PYH3_k127_1917341_25 Belongs to the Nudix hydrolase family K01515,K03574 - 3.6.1.13,3.6.1.55 0.000000000000000000000000000454 125.0
PYH3_k127_1917341_26 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains - GO:0003674,GO:0003700,GO:0004857,GO:0006355,GO:0008073,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010967,GO:0019219,GO:0019222,GO:0030234,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0033238,GO:0042979,GO:0043086,GO:0044092,GO:0045893,GO:0045935,GO:0048518,GO:0048522,GO:0050789,GO:0050790,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0065009,GO:0080090,GO:0098772,GO:0140110,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000001216 85.0
PYH3_k127_1917341_3 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003841 517.0
PYH3_k127_1917341_4 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003034 488.0
PYH3_k127_1917341_5 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 447.0
PYH3_k127_1917341_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 380.0
PYH3_k127_1917341_7 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 387.0
PYH3_k127_1917341_8 Cobalt uptake substrate-specific transmembrane region K02007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 371.0
PYH3_k127_1917341_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 366.0
PYH3_k127_1947353_0 Protein of unknown function, DUF255 K06888 - - 5.25e-198 634.0
PYH3_k127_1947353_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002657 578.0
PYH3_k127_1947353_2 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 381.0
PYH3_k127_1947353_3 Lycopene cyclase protein K10960,K21401 - 1.3.1.111,1.3.1.83,1.3.99.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000005626 275.0
PYH3_k127_1947353_4 6-phosphogluconolactonase K01057 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009051,GO:0009117,GO:0009987,GO:0016787,GO:0016788,GO:0017057,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0052689,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 3.1.1.31 0.00000000000000000000000000000000000000000000000000001092 197.0
PYH3_k127_1947353_5 Putative TM nitroreductase - - - 0.000000000000000000000000000000006961 134.0
PYH3_k127_1947353_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0007555 45.0
PYH3_k127_1956153_0 Zn-dependent protease - - - 0.0004457 53.0
PYH3_k127_1977426_0 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000484 276.0
PYH3_k127_1977426_1 Outer membrane lipoprotein-sorting protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002831 262.0
PYH3_k127_1977426_2 MacB-like periplasmic core domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000635 244.0
PYH3_k127_1977426_3 ABC-type transport system involved in lipoprotein release permease component - - - 0.000000000000000000000000000000000000000000000000000000002669 216.0
PYH3_k127_1977426_4 - - - - 0.00000000000003185 86.0
PYH3_k127_2135979_0 Belongs to the UPF0234 family K09767 - - 0.0000000000000000000000000000000000000000000000000008187 188.0
PYH3_k127_2135979_1 Domain of unknown function (DUF4349) - - - 0.0000000000000000000007606 107.0
PYH3_k127_2135979_2 - - - - 0.000000000000001017 91.0
PYH3_k127_2175845_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004279 415.0
PYH3_k127_2175845_1 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001628 270.0
PYH3_k127_2175845_2 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000006383 117.0
PYH3_k127_2186598_0 SMART Nucleotide binding protein PINc K07175 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 468.0
PYH3_k127_2186598_1 PFAM Integrase, catalytic core - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 430.0
PYH3_k127_2186598_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000719 180.0
PYH3_k127_2186598_3 TIGRFAM tol-pal system protein YbgF - - - 0.00003723 56.0
PYH3_k127_2196912_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 357.0
PYH3_k127_2196912_1 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000002188 199.0
PYH3_k127_2196912_2 - - - - 0.0000000000000000000000000000000000000000000000001186 184.0
PYH3_k127_2196912_3 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000003157 188.0
PYH3_k127_2196912_4 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.0000000000000000000000000000000000000000000000003414 183.0
PYH3_k127_2245378_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 3.071e-228 712.0
PYH3_k127_2245378_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 445.0
PYH3_k127_2245378_2 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007272 289.0
PYH3_k127_2245378_3 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002763 254.0
PYH3_k127_2245378_4 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.0000000000000000000000000006561 117.0
PYH3_k127_2245378_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000008022 70.0
PYH3_k127_2247992_0 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 321.0
PYH3_k127_2247992_1 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000001001 218.0
PYH3_k127_2247992_2 - - - - 0.0000000007051 59.0
PYH3_k127_2331322_0 Belongs to the CarB family K01955 - 6.3.5.5 2.27e-205 648.0
PYH3_k127_2331322_1 Cytochrome c552 K03385 - 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 447.0
PYH3_k127_2331322_2 Catalyzes the conversion of dihydroorotate to orotate with NAD( ) as electron acceptor K00254,K02823,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 358.0
PYH3_k127_2331322_3 metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007654 293.0
PYH3_k127_2331322_4 orotate phosphoribosyltransferase activity K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000006276 197.0
PYH3_k127_2331322_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 GO:0003674,GO:0003824,GO:0004590,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006207,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019856,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046112,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.0000000000000000000000000000000000000000000000000003144 194.0
PYH3_k127_2331322_6 Oxidoreductase NAD-binding domain K02823 - - 0.0000000000000000000000000000000000000000000009937 177.0
PYH3_k127_2331322_7 cheY-homologous receiver domain - - - 0.0000000000000000000000003768 109.0
PYH3_k127_2331322_8 Transglutaminase/protease-like homologues - - - 0.0000000000000000000008584 110.0
PYH3_k127_238214_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0000502,GO:0002020,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009376,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0019899,GO:0019904,GO:0030163,GO:0030164,GO:0030312,GO:0030554,GO:0031333,GO:0031597,GO:0032271,GO:0032272,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0043254,GO:0043335,GO:0044087,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051301,GO:0051704,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0097718,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1904949,GO:1905368,GO:1905369 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 463.0
PYH3_k127_238214_1 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003724 295.0
PYH3_k127_238214_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000001893 255.0
PYH3_k127_2481680_0 Domain of unknown function (DUF3552) K18682 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003277 614.0
PYH3_k127_2481680_1 Carbamoyl-phosphate synthetase large chain domain protein K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 587.0
PYH3_k127_2481680_10 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000000000000001825 222.0
PYH3_k127_2481680_11 type IV pilus secretin PilQ K02666 - - 0.0000000000000000000000000000000000000000000000000006816 196.0
PYH3_k127_2481680_12 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000001638 171.0
PYH3_k127_2481680_13 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000339 151.0
PYH3_k127_2481680_14 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.0000000000000000000000000000007998 128.0
PYH3_k127_2481680_15 5-Formyltetrahydrofolate Cyclo-Ligase K01934 GO:0003674,GO:0003824,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0018130,GO:0019438,GO:0019752,GO:0022611,GO:0030272,GO:0032502,GO:0034641,GO:0035999,GO:0042398,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046653,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.2 0.00000000000000000000000007843 114.0
PYH3_k127_2481680_16 Roadblock/LC7 domain - - - 0.0000000000000000000002072 101.0
PYH3_k127_2481680_17 biosynthesis protein K01104 - 3.1.3.48 0.00000000000000000009299 102.0
PYH3_k127_2481680_18 Tetratricopeptide repeat - - - 0.0000000000000000001924 104.0
PYH3_k127_2481680_19 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000003016 79.0
PYH3_k127_2481680_2 TIGRFAM Arginyl-tRNA synthetase K01887 GO:0003674,GO:0003824,GO:0004812,GO:0004814,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006420,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 588.0
PYH3_k127_2481680_20 Sporulation related domain - - - 0.00003751 56.0
PYH3_k127_2481680_3 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 526.0
PYH3_k127_2481680_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000765 437.0
PYH3_k127_2481680_5 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008834 338.0
PYH3_k127_2481680_6 OB-fold nucleic acid binding domain K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003414 325.0
PYH3_k127_2481680_7 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 315.0
PYH3_k127_2481680_8 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000001049 252.0
PYH3_k127_2481680_9 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000002206 257.0
PYH3_k127_2548078_0 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 288.0
PYH3_k127_2548078_1 TIGRFAM TIGR00268 family protein K06864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004479 256.0
PYH3_k127_2548078_2 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000000000000000000000005738 202.0
PYH3_k127_2548078_3 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000004396 172.0
PYH3_k127_2548078_4 Tetratricopeptide repeat - - - 0.0000009457 60.0
PYH3_k127_2548078_5 PAP2 superfamily - - - 0.000001104 61.0
PYH3_k127_2548078_6 - - - - 0.0002915 49.0
PYH3_k127_2601414_0 DNA polymerase K02347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 574.0
PYH3_k127_2657747_0 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000002012 168.0
PYH3_k127_2659388_0 Ammonium transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001768 534.0
PYH3_k127_2659388_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000003104 230.0
PYH3_k127_2659388_2 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000005909 205.0
PYH3_k127_2659388_3 Belongs to the P(II) protein family K04752 - - 0.0000000000000000000000000000000000000005059 151.0
PYH3_k127_2659388_4 - - - - 0.0000003102 57.0
PYH3_k127_2669917_0 TonB dependent receptor K02014,K16092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 415.0
PYH3_k127_2669917_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 349.0
PYH3_k127_2669917_2 COG1032 Fe-S oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 295.0
PYH3_k127_2669917_3 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000004978 268.0
PYH3_k127_2669917_4 PFAM periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006017 249.0
PYH3_k127_2669917_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000004067 201.0
PYH3_k127_2669917_6 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000142 82.0
PYH3_k127_2702451_0 methionyl-tRNA aminoacylation K01874 GO:0003674,GO:0003824,GO:0004812,GO:0004825,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006431,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 7.781e-212 688.0
PYH3_k127_2702451_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006366 418.0
PYH3_k127_2702451_10 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000008445 180.0
PYH3_k127_2702451_11 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000002621 137.0
PYH3_k127_2702451_12 cheY-homologous receiver domain - - - 0.00000000000000000000000000000005596 131.0
PYH3_k127_2702451_13 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000007605 137.0
PYH3_k127_2702451_14 PFAM Class I peptide chain release factor K15034 - - 0.00000000000000000021 93.0
PYH3_k127_2702451_15 - - - - 0.0000000000000000003582 96.0
PYH3_k127_2702451_16 Heptaprenyl diphosphate synthase component I K00805 - 2.5.1.30 0.0000000000001089 81.0
PYH3_k127_2702451_17 PFAM Positive regulator of sigma(E) RseC MucC K03803 - - 0.00000000004025 69.0
PYH3_k127_2702451_18 NusG domain II - - - 0.00000001048 67.0
PYH3_k127_2702451_2 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002119 368.0
PYH3_k127_2702451_3 S4 RNA-binding domain K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003713 309.0
PYH3_k127_2702451_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000001062 251.0
PYH3_k127_2702451_5 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000009167 250.0
PYH3_k127_2702451_6 PSP1 C-terminal conserved region - - - 0.0000000000000000000000000000000000000000000000000000000000001154 236.0
PYH3_k127_2702451_7 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000008353 216.0
PYH3_k127_2702451_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000000000000000114 194.0
PYH3_k127_2702451_9 molybdenum cofactor - - - 0.00000000000000000000000000000000000000000000000003917 185.0
PYH3_k127_2719371_0 A G-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002917 269.0
PYH3_k127_2719371_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002687 259.0
PYH3_k127_2719371_2 Serine aminopeptidase, S33 K06889 - - 0.000000000000000000000000000000000000000000000000000000000000001497 228.0
PYH3_k127_2719371_3 phosphatase activity K01560,K07025,K20866,K21063 GO:0003674,GO:0003824,GO:0006766,GO:0006767,GO:0006771,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042578,GO:0042726,GO:0042727,GO:0043726,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 3.1.3.10,3.1.3.104,3.8.1.2 0.0000000000000000000000000000003918 130.0
PYH3_k127_2719371_4 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000006074 112.0
PYH3_k127_2719371_5 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.0000000000000000249 91.0
PYH3_k127_2719371_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000003341 87.0
PYH3_k127_2719371_7 - - - - 0.00000000000004652 84.0
PYH3_k127_2719371_8 Protein of unknown function (DUF1003) - - - 0.00000005839 63.0
PYH3_k127_2720134_0 alginic acid biosynthetic process K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004546 278.0
PYH3_k127_2720134_1 oligosaccharyl transferase activity - - - 0.00000000000000000000000006282 124.0
PYH3_k127_2720134_2 PQQ-like domain - - - 0.00000000000000003135 97.0
PYH3_k127_2720134_3 Predicted permease - - - 0.00000000000002488 74.0
PYH3_k127_2860188_0 ASPIC and UnbV - - - 8.915e-196 623.0
PYH3_k127_2860188_1 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 497.0
PYH3_k127_2860188_10 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000009061 238.0
PYH3_k127_2860188_11 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000000000000000000000000000000000000000000000000002232 233.0
PYH3_k127_2860188_12 domain protein - - - 0.0000000000000000000000000000000000000000000000000000002746 208.0
PYH3_k127_2860188_14 Tetrapyrrole (Corrin/Porphyrin) Methylases - - - 0.000000000000000000000000000000000000000000000000001126 197.0
PYH3_k127_2860188_15 PQQ-like domain - - - 0.000000000000000000000000000000000000000000000000001263 210.0
PYH3_k127_2860188_16 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000000000000000000000000000002063 196.0
PYH3_k127_2860188_17 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000009693 163.0
PYH3_k127_2860188_18 - - - - 0.000000000000000000000000000000000000002377 163.0
PYH3_k127_2860188_2 denitrification pathway K02569,K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 492.0
PYH3_k127_2860188_20 nitric oxide dioxygenase activity - - - 0.000000000000000000000000001648 119.0
PYH3_k127_2860188_21 Substrate binding domain of ABC-type glycine betaine transport system - - - 0.00000000000000000000000006741 124.0
PYH3_k127_2860188_22 - - - - 0.000000000000000000000001497 115.0
PYH3_k127_2860188_23 amine dehydrogenase activity - - - 0.0000000000000002739 92.0
PYH3_k127_2860188_25 - - - - 0.00000000005622 67.0
PYH3_k127_2860188_26 formylmethanofuran dehydrogenase, subunit E K11261 - 1.2.7.12 0.0000000001018 69.0
PYH3_k127_2860188_27 ResB protein required for cytochrome c biosynthesis K07399 - - 0.000000122 59.0
PYH3_k127_2860188_28 peptidase U32 - - - 0.00004106 56.0
PYH3_k127_2860188_3 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 397.0
PYH3_k127_2860188_4 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 409.0
PYH3_k127_2860188_5 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 379.0
PYH3_k127_2860188_6 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001727 289.0
PYH3_k127_2860188_7 Predicted permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009154 267.0
PYH3_k127_2860188_8 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
PYH3_k127_2860188_9 PFAM ATP-binding region, ATPase domain protein K07709 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000003127 254.0
PYH3_k127_286451_0 D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase K01621 - 4.1.2.22,4.1.2.9 3.534e-313 989.0
PYH3_k127_286451_1 DEAD-box RNA helicase involved in RNA degradation. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K03732 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 392.0
PYH3_k127_286451_10 MaoC like domain - - - 0.000000000000000000000000000000000000000000000000000003684 194.0
PYH3_k127_286451_11 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000005005 195.0
PYH3_k127_286451_12 - - - - 0.0000000000000000000000000000000000000000000008091 178.0
PYH3_k127_286451_13 Calcineurin-like phosphoesterase superfamily domain - - - 0.00000000000000000000000000000000000001913 161.0
PYH3_k127_286451_14 - - - - 0.0000000000003428 75.0
PYH3_k127_286451_15 Pentapeptide repeats (9 copies) - - - 0.0001606 53.0
PYH3_k127_286451_2 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006195 280.0
PYH3_k127_286451_3 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003007 292.0
PYH3_k127_286451_4 anaerobic respiration - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001264 275.0
PYH3_k127_286451_5 mRNA cleavage and polyadenylation factor CLP1 P-loop K06947 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001379 262.0
PYH3_k127_286451_6 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000001301 258.0
PYH3_k127_286451_7 TIGRFAM phosphate binding protein K02040 - - 0.0000000000000000000000000000000000000000000000000000000001677 213.0
PYH3_k127_286451_8 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000108 206.0
PYH3_k127_286451_9 TIGRFAM phosphate binding protein K02040 - - 0.00000000000000000000000000000000000000000000000000000005469 209.0
PYH3_k127_2974377_0 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.0 1056.0
PYH3_k127_2974377_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000851 537.0
PYH3_k127_2974377_2 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002271 248.0
PYH3_k127_2974377_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 GO:0000287,GO:0003674,GO:0003824,GO:0004170,GO:0005488,GO:0006139,GO:0006220,GO:0006221,GO:0006226,GO:0006244,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009141,GO:0009143,GO:0009147,GO:0009149,GO:0009157,GO:0009162,GO:0009165,GO:0009166,GO:0009176,GO:0009177,GO:0009200,GO:0009204,GO:0009211,GO:0009213,GO:0009219,GO:0009221,GO:0009223,GO:0009262,GO:0009263,GO:0009264,GO:0009265,GO:0009394,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046078,GO:0046080,GO:0046081,GO:0046385,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0046872,GO:0047429,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0072529,GO:0090407,GO:1901135,GO:1901136,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.6.1.23 0.00000004781 54.0
PYH3_k127_3010417_0 Participates in both transcription termination and antitermination K02600 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009766 384.0
PYH3_k127_3010417_1 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070039,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.185 0.000000000000000000000000000000000007761 144.0
PYH3_k127_3010417_2 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000002785 138.0
PYH3_k127_3010417_3 ribosomal protein L7Ae L30e S12e Gadd45 K07742 - - 0.0000000000000000005937 94.0
PYH3_k127_3010417_4 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0002962 49.0
PYH3_k127_3026462_0 Bacterial DNA polymerase III alpha subunit K02337,K14162 GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0031668,GO:0033554,GO:0050896,GO:0051716,GO:0071496 2.7.7.7 0.0 1189.0
PYH3_k127_3026462_1 Predicted permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 427.0
PYH3_k127_3026462_2 impB/mucB/samB family K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001642 405.0
PYH3_k127_3026462_3 Represses a number of genes involved in the response to DNA damage (SOS response) K01356,K03503 - 3.4.21.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 301.0
PYH3_k127_3026462_4 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001176 233.0
PYH3_k127_3026462_5 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000004867 105.0
PYH3_k127_3026462_6 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000000000001178 109.0
PYH3_k127_3074305_0 AcrB/AcrD/AcrF family K03296 - - 1.246e-269 846.0
PYH3_k127_3074305_1 AcrB/AcrD/AcrF family K03296 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 415.0
PYH3_k127_3074305_2 - - - - 0.0000000000000000000000000000000002799 136.0
PYH3_k127_3232071_0 D-isomer specific 2-hydroxyacid dehydrogenase catalytic region K00018 - 1.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 396.0
PYH3_k127_3232071_1 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000001113 154.0
PYH3_k127_3232071_2 GDYXXLXY protein - - - 0.0000000000000000005238 97.0
PYH3_k127_3232071_3 TIGRFAM C_GCAxxG_C_C family - - - 0.000000000000004443 81.0
PYH3_k127_3232071_5 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.00005272 48.0
PYH3_k127_3296091_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009967 510.0
PYH3_k127_3296091_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 501.0
PYH3_k127_3296091_10 RDD family - - - 0.000000001403 64.0
PYH3_k127_3296091_2 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 334.0
PYH3_k127_3296091_3 NAD-dependent glycerol-3-phosphate dehydrogenase domain protein K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 321.0
PYH3_k127_3296091_4 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 0.000000000000000000000000000000000000000000000000000001122 194.0
PYH3_k127_3296091_5 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000001789 142.0
PYH3_k127_3296091_6 PFAM Phosphatidylglycerophosphatase A K01095 - 3.1.3.27 0.000000000000000000000000000007015 124.0
PYH3_k127_3296091_7 Belongs to the CinA family K03742,K03743 - 3.5.1.42 0.0000000000000000000000000007493 126.0
PYH3_k127_3296091_8 - - - - 0.000000000000000002941 90.0
PYH3_k127_3296091_9 Modulates RecA activity K03565 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000004538 82.0
PYH3_k127_3317790_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007314 406.0
PYH3_k127_3317790_1 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 312.0
PYH3_k127_3317790_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000001487 147.0
PYH3_k127_33229_0 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006385 510.0
PYH3_k127_33229_1 Penicillin-binding protein 2 K05515 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005626 515.0
PYH3_k127_33229_10 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000001363 175.0
PYH3_k127_33229_11 SPTR CopG domain protein DNA-binding domain protein - - - 0.0000000000000000000000000001474 116.0
PYH3_k127_33229_12 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.0000000000000000000000000008966 114.0
PYH3_k127_33229_14 - - - - 0.00000752 52.0
PYH3_k127_33229_2 Flavin containing amine oxidoreductase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005677 503.0
PYH3_k127_33229_3 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008954 447.0
PYH3_k127_33229_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008018 378.0
PYH3_k127_33229_5 Transposase IS200 like K07491 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000406 325.0
PYH3_k127_33229_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009318 284.0
PYH3_k127_33229_7 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000000000378 245.0
PYH3_k127_33229_8 6-phosphofructokinase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000001991 208.0
PYH3_k127_33229_9 - - - - 0.000000000000000000000000000000000000000000000000001537 189.0
PYH3_k127_3493575_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 3.031e-244 782.0
PYH3_k127_3493575_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and metabolism K00990 - 2.7.7.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 595.0
PYH3_k127_3493575_10 AI-2E family transporter - - - 0.000000000000000000000000000000000000002589 160.0
PYH3_k127_3493575_11 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000005222 137.0
PYH3_k127_3493575_12 nucleotidyltransferase activity K01154,K07076,K18842 - 3.1.21.3 0.00000000000000000000000000000005046 128.0
PYH3_k127_3493575_13 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.00000000000000000000000000000007401 133.0
PYH3_k127_3493575_14 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000005583 115.0
PYH3_k127_3493575_16 - - - - 0.0000000000000003211 79.0
PYH3_k127_3493575_17 HicA toxin of bacterial toxin-antitoxin, - - - 0.00000000000004481 75.0
PYH3_k127_3493575_18 - - - - 0.00000000007293 70.0
PYH3_k127_3493575_19 HEPN domain K09132 - - 0.000000000451 67.0
PYH3_k127_3493575_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052,K07246 - 1.1.1.83,1.1.1.85,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005864 558.0
PYH3_k127_3493575_20 COG NOG15344 non supervised orthologous group - - - 0.00001857 47.0
PYH3_k127_3493575_3 AAA ATPase, central domain protein K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 476.0
PYH3_k127_3493575_4 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 376.0
PYH3_k127_3493575_5 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003875 357.0
PYH3_k127_3493575_6 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000001154 278.0
PYH3_k127_3493575_7 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000008707 229.0
PYH3_k127_3493575_8 COG NOG14600 non supervised orthologous group - - - 0.00000000000000000000000000000000000000000000000000000000001157 207.0
PYH3_k127_3493575_9 Bis-adenosyl-polyphosphate hydrolase, FHIT domain-containing K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000001831 184.0
PYH3_k127_354626_0 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 370.0
PYH3_k127_354626_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000003349 195.0
PYH3_k127_354626_3 Protein kinase domain - - - 0.000000001756 60.0
PYH3_k127_3556031_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 2.977e-195 619.0
PYH3_k127_3556031_1 PFAM Cytochrome C assembly protein K02198 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 556.0
PYH3_k127_3556031_10 ABC transporter K02193 - 3.6.3.41 0.00000000000000000000000000000000000000000000000000000008167 207.0
PYH3_k127_3556031_11 Cytochrome C assembly protein K02195 - - 0.0000000000000000000000000000000000000000000000000000003976 211.0
PYH3_k127_3556031_12 Extradiol ring-cleavage dioxygenase, class III K06990,K09141 - - 0.00000000000000000000000000000000000000000000000000000142 196.0
PYH3_k127_3556031_13 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000001953 171.0
PYH3_k127_3556031_14 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000001572 167.0
PYH3_k127_3556031_15 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000009853 161.0
PYH3_k127_3556031_16 CcmB protein K02194 - - 0.0000000000000000000000000000000000000002249 159.0
PYH3_k127_3556031_17 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000001983 143.0
PYH3_k127_3556031_18 cell redox homeostasis K02199 - - 0.00000000000000000000000000000000003705 141.0
PYH3_k127_3556031_19 lyase activity - - - 0.0000000000000000000000000000001085 143.0
PYH3_k127_3556031_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 513.0
PYH3_k127_3556031_20 phosphorelay signal transduction system - - - 0.0000000000000000000000000008496 119.0
PYH3_k127_3556031_21 Tetratricopeptide repeat - - - 0.00000000000000000000001299 113.0
PYH3_k127_3556031_22 Helix-turn-helix domain - - - 0.0000000000000000000002785 105.0
PYH3_k127_3556031_23 PASTA K12132 - 2.7.11.1 0.000000000000000000005704 108.0
PYH3_k127_3556031_24 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000006785 94.0
PYH3_k127_3556031_25 YacP-like NYN domain K06962 - - 0.000000000000072 78.0
PYH3_k127_3556031_26 conserved protein UCP033563 - - - 0.000000001513 59.0
PYH3_k127_3556031_27 Cell envelope-related transcriptional attenuator domain - - - 0.0009433 51.0
PYH3_k127_3556031_3 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 353.0
PYH3_k127_3556031_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 314.0
PYH3_k127_3556031_5 NUBPL iron-transfer P-loop NTPase K04562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 295.0
PYH3_k127_3556031_6 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000977 280.0
PYH3_k127_3556031_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001045 281.0
PYH3_k127_3556031_8 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000007871 255.0
PYH3_k127_3556031_9 Protein of unknown function DUF116 K09729 - - 0.00000000000000000000000000000000000000000000000000000000000000000008081 244.0
PYH3_k127_3590203_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 496.0
PYH3_k127_3763676_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 604.0
PYH3_k127_3763676_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000763 367.0
PYH3_k127_3763676_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 338.0
PYH3_k127_3763676_3 ABC-2 type transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 310.0
PYH3_k127_3763676_4 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007247 308.0
PYH3_k127_3763676_5 Barrel-sandwich domain of CusB or HlyD membrane-fusion K01993 - - 0.0000000000000000000000000000000000000000000000000006014 204.0
PYH3_k127_3763676_6 transcriptional regulator - GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043565,GO:0044212,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1903506,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000000000000001983 121.0
PYH3_k127_3763676_7 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT - - - 0.000000000000006916 89.0
PYH3_k127_3763676_8 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000007862 78.0
PYH3_k127_3784573_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 4.043e-246 775.0
PYH3_k127_3784573_1 ATPase with chaperone activity K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 479.0
PYH3_k127_3784573_10 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000001602 147.0
PYH3_k127_3784573_11 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000003311 102.0
PYH3_k127_3784573_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
PYH3_k127_3784573_3 Belongs to the ABC transporter superfamily K02031,K02032,K15583 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006571 381.0
PYH3_k127_3784573_4 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007179 372.0
PYH3_k127_3784573_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 355.0
PYH3_k127_3784573_6 HrcA protein C terminal domain K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 321.0
PYH3_k127_3784573_7 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001404 264.0
PYH3_k127_3784573_8 SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000738 194.0
PYH3_k127_3784573_9 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000003219 210.0
PYH3_k127_3791114_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 4.666e-265 831.0
PYH3_k127_3791114_1 Conserved protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007472 267.0
PYH3_k127_3791114_2 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000915 198.0
PYH3_k127_3791114_3 PFAM FMN-binding domain - - - 0.000000000000000000000000000000000000000000000000003245 193.0
PYH3_k127_3791114_4 DUF218 domain - - - 0.000000000000002189 87.0
PYH3_k127_3791114_6 - - - - 0.000002271 54.0
PYH3_k127_3819035_0 PFAM aminotransferase, class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 482.0
PYH3_k127_3819035_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 406.0
PYH3_k127_3819035_10 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000001944 227.0
PYH3_k127_3819035_11 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000007737 184.0
PYH3_k127_3819035_12 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000001382 166.0
PYH3_k127_3819035_13 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0000000000000000000000000000000000000000004511 162.0
PYH3_k127_3819035_14 Conserved hypothetical protein 95 K08316 - 2.1.1.171 0.000000000000000000000000000000000003863 143.0
PYH3_k127_3819035_15 DNA polymerase III, delta' subunit K02340 - 2.7.7.7 0.000000000000000000000000000000005161 141.0
PYH3_k127_3819035_16 Amidohydrolase - - - 0.0000000000000000000000000006298 123.0
PYH3_k127_3819035_17 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000388 113.0
PYH3_k127_3819035_18 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000005336 109.0
PYH3_k127_3819035_19 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02487 - - 0.00000000000000000005662 98.0
PYH3_k127_3819035_2 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K01598,K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 392.0
PYH3_k127_3819035_20 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000003498 79.0
PYH3_k127_3819035_21 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000005818 56.0
PYH3_k127_3819035_22 TamB, inner membrane protein subunit of TAM complex K09800 - - 0.00005442 57.0
PYH3_k127_3819035_3 peptidase M42 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 381.0
PYH3_k127_3819035_4 PFAM Phosphate acetyl butaryl transferase K00625 GO:0006082,GO:0006083,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016053,GO:0016999,GO:0017000,GO:0017144,GO:0019413,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002712 347.0
PYH3_k127_3819035_5 surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004062 311.0
PYH3_k127_3819035_6 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006296 279.0
PYH3_k127_3819035_7 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000178 280.0
PYH3_k127_3819035_8 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000001447 250.0
PYH3_k127_3819035_9 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000003201 244.0
PYH3_k127_3819312_0 PFAM Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 612.0
PYH3_k127_3819312_1 PFAM Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 432.0
PYH3_k127_3819312_2 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 357.0
PYH3_k127_3819312_3 PFAM metal-dependent phosphohydrolase HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002112 279.0
PYH3_k127_3819312_4 HEAT repeats - - - 0.00000000000000000000000000000001983 145.0
PYH3_k127_3819312_5 PFAM SAICAR synthetase K01923,K13713 - 6.3.2.6,6.3.4.13 0.00000000000000000001367 92.0
PYH3_k127_3819312_6 deoxyhypusine monooxygenase activity - - - 0.000009376 56.0
PYH3_k127_3831906_0 Domain of unknown function (DUF4143) K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 576.0
PYH3_k127_3831906_1 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000363 574.0
PYH3_k127_3831906_10 transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000001047 176.0
PYH3_k127_3831906_11 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 GO:0000309,GO:0003674,GO:0003824,GO:0004515,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.7.18 0.000000000000000000000000000000000000000000000873 173.0
PYH3_k127_3831906_12 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000002064 169.0
PYH3_k127_3831906_13 PFAM Phosphoribosyltransferase - - - 0.000000000000000000000000000000000002423 149.0
PYH3_k127_3831906_14 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000001803 133.0
PYH3_k127_3831906_15 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000002394 130.0
PYH3_k127_3831906_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000003848 117.0
PYH3_k127_3831906_17 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000001572 109.0
PYH3_k127_3831906_18 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000005288 111.0
PYH3_k127_3831906_19 PBS lyase HEAT domain protein repeat-containing protein - - - 0.0000000000000007167 92.0
PYH3_k127_3831906_2 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 573.0
PYH3_k127_3831906_20 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.000000000000004197 84.0
PYH3_k127_3831906_3 Aldehyde dehydrogenase family K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 497.0
PYH3_k127_3831906_4 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003562 382.0
PYH3_k127_3831906_5 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 382.0
PYH3_k127_3831906_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 GO:0003674,GO:0003824,GO:0004349,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0018130,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 376.0
PYH3_k127_3831906_7 Inositol monophosphatase family K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000000000000000000000000000000005784 260.0
PYH3_k127_3831906_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000002297 207.0
PYH3_k127_3831906_9 LysE type translocator - - - 0.000000000000000000000000000000000000000000000000001453 190.0
PYH3_k127_3840108_0 HWE histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006164 295.0
PYH3_k127_3840108_1 TIGRFAM phosphonate ABC transporter, periplasmic phosphonate-binding protein K02044 - - 0.00000000000000000000000007777 116.0
PYH3_k127_3840108_2 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000189 85.0
PYH3_k127_3840108_3 Protein of unknown function (DUF2934) - - - 0.0000000000001393 74.0
PYH3_k127_3840108_4 Rubrerythrin - - - 0.0000000000004556 78.0
PYH3_k127_3840108_5 PilZ domain - - - 0.0000003712 55.0
PYH3_k127_3862615_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 537.0
PYH3_k127_3862615_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 316.0
PYH3_k127_3862615_2 COG0767 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005072 290.0
PYH3_k127_3862615_3 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001129 264.0
PYH3_k127_3862615_4 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000003259 133.0
PYH3_k127_3928729_0 Belongs to the glutamate synthase family - - - 1.164e-245 766.0
PYH3_k127_3928729_1 PFAM glutamate synthase alpha subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001116 276.0
PYH3_k127_3928729_2 PFAM Glutamine amidotransferase, class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003198 244.0
PYH3_k127_3930018_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657,K01665 - 2.6.1.85,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 355.0
PYH3_k127_3930018_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009309 301.0
PYH3_k127_3930018_2 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000005845 233.0
PYH3_k127_3930018_3 Belongs to the TrpC family K01609,K13498 GO:0003674,GO:0003824,GO:0004425,GO:0016829,GO:0016830,GO:0016831 4.1.1.48,5.3.1.24 0.00000000000000000002895 99.0
PYH3_k127_3934874_0 Elongation factor G C-terminus K06207 - - 4.299e-297 921.0
PYH3_k127_3934874_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 2.121e-201 647.0
PYH3_k127_3934874_10 Aminoacyl-tRNA editing domain K19055 - - 0.00000000000000000000000000000000000001203 154.0
PYH3_k127_3934874_11 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000005214 126.0
PYH3_k127_3934874_12 Protein of Unknown function (DUF2784) - - - 0.0000000002632 71.0
PYH3_k127_3934874_13 Tetratricopeptide repeat-like domain - - - 0.000000003013 66.0
PYH3_k127_3934874_14 GXGXG motif - - - 0.0007318 42.0
PYH3_k127_3934874_2 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 557.0
PYH3_k127_3934874_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K13015 - 1.1.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 537.0
PYH3_k127_3934874_4 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 377.0
PYH3_k127_3934874_5 Bacterial regulatory protein, Fis family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 368.0
PYH3_k127_3934874_6 GDP-mannose 4,6 dehydratase K01784,K17947 - 5.1.3.2,5.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007829 353.0
PYH3_k127_3934874_7 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000009355 231.0
PYH3_k127_3934874_8 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000004826 192.0
PYH3_k127_3934874_9 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000001081 188.0
PYH3_k127_3953583_0 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331 - 1.12.1.3,1.6.5.3 2.221e-240 757.0
PYH3_k127_3953583_1 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 5.069e-210 670.0
PYH3_k127_3953583_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 324.0
PYH3_k127_3953583_11 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002879 280.0
PYH3_k127_3953583_12 it plays a direct role in the translocation of protons across the membrane K02108 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0031226,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042777,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
PYH3_k127_3953583_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000002471 225.0
PYH3_k127_3953583_14 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000004673 183.0
PYH3_k127_3953583_15 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000004647 173.0
PYH3_k127_3953583_16 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000003035 149.0
PYH3_k127_3953583_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338,K03941 GO:0003674,GO:0003824,GO:0003954,GO:0008150,GO:0008152,GO:0016491,GO:0016651,GO:0016655,GO:0050136,GO:0055114 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000007698 141.0
PYH3_k127_3953583_18 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000001615 135.0
PYH3_k127_3953583_19 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000007881 126.0
PYH3_k127_3953583_2 TIGRFAM formate dehydrogenase, alpha subunit K00123,K00336,K05299 - 1.17.1.10,1.17.1.9,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005324 626.0
PYH3_k127_3953583_20 COG1905 NADH ubiquinone oxidoreductase 24 kD subunit K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000008037 130.0
PYH3_k127_3953583_21 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.00000000000000000000000000004621 118.0
PYH3_k127_3953583_22 Belongs to the P(II) protein family - - - 0.0000000000000000000000002129 109.0
PYH3_k127_3953583_23 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000003173 92.0
PYH3_k127_3953583_24 Tetratricopeptide repeat - - - 0.000000000000002014 91.0
PYH3_k127_3953583_25 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000005743 69.0
PYH3_k127_3953583_26 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter K02116 - - 0.00000002713 57.0
PYH3_k127_3953583_3 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 587.0
PYH3_k127_3953583_4 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008548 554.0
PYH3_k127_3953583_5 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003826 561.0
PYH3_k127_3953583_6 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 538.0
PYH3_k127_3953583_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 501.0
PYH3_k127_3953583_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 392.0
PYH3_k127_3953583_9 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 353.0
PYH3_k127_3978109_0 NIL - - - 0.000000000000000000000000000000000005158 141.0
PYH3_k127_3978109_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000003565 136.0
PYH3_k127_3978109_2 long-chain fatty acid transport protein - - - 0.000000002863 58.0
PYH3_k127_3978109_3 Domain of unknown function (DUF4440) - - - 0.0004277 49.0
PYH3_k127_3994572_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 471.0
PYH3_k127_3994572_1 SOUL heme-binding protein - - - 0.000000000000000000000000000000000000000001668 164.0
PYH3_k127_3994572_2 - K07341 - - 0.000000000000000002882 90.0
PYH3_k127_4035963_0 YceI-like domain - - - 0.00000000000000009176 82.0
PYH3_k127_4036072_0 Heat shock 70 kDa protein K04043 - - 5.927e-265 829.0
PYH3_k127_4036072_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970,K00974 - 2.7.7.19,2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007766 302.0
PYH3_k127_4036072_2 peroxiredoxin activity - - - 0.000000000000000000000000004715 126.0
PYH3_k127_4036072_3 Thioredoxin-like - - - 0.000000000000000001563 98.0
PYH3_k127_4036072_4 YceI-like domain - - - 0.000000000000000003852 86.0
PYH3_k127_4036072_5 Thiamine-binding protein - - - 0.00000000000002565 77.0
PYH3_k127_4036072_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00009891 54.0
PYH3_k127_4038746_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1690.0
PYH3_k127_4038746_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 393.0
PYH3_k127_4038746_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 342.0
PYH3_k127_4038746_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003737 297.0
PYH3_k127_4038746_4 Uncharacterised ArCR, COG2043 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001557 271.0
PYH3_k127_4038746_5 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001055 270.0
PYH3_k127_4038746_6 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000004628 266.0
PYH3_k127_4038746_7 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009405,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0015036,GO:0016209,GO:0016491,GO:0016667,GO:0016671,GO:0016684,GO:0019725,GO:0020012,GO:0030312,GO:0030682,GO:0032843,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0071944,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
PYH3_k127_4038746_8 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K01256,K02563,K02652,K08776,K12132 - 2.4.1.227,2.7.11.1,3.4.11.2 0.0000000001675 69.0
PYH3_k127_4051615_0 Belongs to the CarB family K01955 - 6.3.5.5 1.266e-301 934.0
PYH3_k127_4051615_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 GO:0003674,GO:0003824,GO:0004038,GO:0004151,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009112,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046390,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004816 446.0
PYH3_k127_4051615_2 Belongs to the CarA family K01956 - 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 449.0
PYH3_k127_4051615_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000006759 166.0
PYH3_k127_4116080_0 Conserved carboxylase domain K01958 - 6.4.1.1 0.0 1055.0
PYH3_k127_4116080_1 acetyl-CoA carboxylase, biotin carboxylase K01965 - 6.4.1.3 2.883e-236 738.0
PYH3_k127_4116080_2 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 2.22e-230 751.0
PYH3_k127_4116080_3 PFAM ABC transporter K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004754 602.0
PYH3_k127_4116080_4 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 349.0
PYH3_k127_4116080_5 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002476 275.0
PYH3_k127_4126060_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.287e-261 851.0
PYH3_k127_4126060_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 343.0
PYH3_k127_4126060_10 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000005897 167.0
PYH3_k127_4126060_11 SurA N-terminal domain K03769 - 5.2.1.8 0.00000000000000000000000000000000000000001386 165.0
PYH3_k127_4126060_12 Type II secretion system (T2SS), protein E, N-terminal domain - - - 0.000000000000000000000000000000000001149 151.0
PYH3_k127_4126060_13 peptidyl-prolyl cis-trans isomerase activity K02597,K03769,K03771 - 5.2.1.8 0.0000000000000000000009574 107.0
PYH3_k127_4126060_14 Rhodanese Homology Domain - - - 0.0000000000005062 70.0
PYH3_k127_4126060_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116,K03117 - - 0.00000000001654 68.0
PYH3_k127_4126060_16 PFAM RNA-binding S4 domain protein - - - 0.00000000007033 68.0
PYH3_k127_4126060_17 PilZ domain - - - 0.0000000007749 64.0
PYH3_k127_4126060_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 320.0
PYH3_k127_4126060_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005408 276.0
PYH3_k127_4126060_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002192 256.0
PYH3_k127_4126060_5 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000002232 212.0
PYH3_k127_4126060_6 Modulates transcription in response to changes in cellular NADH NAD( ) redox state K01926 - - 0.00000000000000000000000000000000000000000000000000000002816 203.0
PYH3_k127_4126060_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000001685 189.0
PYH3_k127_4126060_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000001178 189.0
PYH3_k127_4126060_9 denitrification pathway K02569,K15876 - - 0.0000000000000000000000000000000000000000000000001777 188.0
PYH3_k127_416399_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169,K00170 - 1.2.7.1 1.211e-299 940.0
PYH3_k127_416399_1 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 GO:0003674,GO:0003824,GO:0004611,GO:0004612,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0008150,GO:0008152,GO:0009058,GO:0016051,GO:0016829,GO:0016830,GO:0016831,GO:0019318,GO:0019319,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0071704,GO:1901576 4.1.1.49 1.38e-241 758.0
PYH3_k127_416399_10 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 304.0
PYH3_k127_416399_11 PQQ-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001332 284.0
PYH3_k127_416399_12 Cytochrome b5-like Heme/Steroid binding domain K07245,K14166 - - 0.0000000000000000000000000000000000000000000000000000000000000004271 232.0
PYH3_k127_416399_13 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000001516 215.0
PYH3_k127_416399_14 Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates K16785 - - 0.0000000000000000000000000000000000000000000000000000001406 205.0
PYH3_k127_416399_15 Putative zinc- or iron-chelating domain - - - 0.000000000000000000000000000000000000000000000001961 178.0
PYH3_k127_416399_16 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000001822 175.0
PYH3_k127_416399_17 PFAM Transglycosylase SLT domain K08309 - - 0.0000000000000000000000000000000000000003517 159.0
PYH3_k127_416399_18 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000001912 143.0
PYH3_k127_416399_19 Molybdopterin-guanine dinucleotide biosynthesis K03753 - - 0.00000000000000000000000000000003217 132.0
PYH3_k127_416399_2 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702,K08999 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009314,GO:0009380,GO:0009628,GO:0032991,GO:0042802,GO:0044424,GO:0044464,GO:0050896,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 517.0
PYH3_k127_416399_20 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000006367 114.0
PYH3_k127_416399_21 QueT transporter - - - 0.0000000000000000000007077 103.0
PYH3_k127_416399_22 Thioesterase superfamily - - - 0.000000000000000001199 93.0
PYH3_k127_416399_23 Integrin alpha (beta-propellor repeats). - - - 0.0000000003082 72.0
PYH3_k127_416399_24 - - - - 0.0001288 50.0
PYH3_k127_416399_3 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 497.0
PYH3_k127_416399_4 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0005575,GO:0005622,GO:0005623,GO:0006950,GO:0006974,GO:0008150,GO:0009380,GO:0009987,GO:0032991,GO:0033554,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:1902494,GO:1905347,GO:1905348,GO:1990391 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008897 445.0
PYH3_k127_416399_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 424.0
PYH3_k127_416399_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 401.0
PYH3_k127_416399_7 PFAM ABC transporter related - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 369.0
PYH3_k127_416399_8 ferredoxin K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 348.0
PYH3_k127_416399_9 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007605 317.0
PYH3_k127_4244463_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008347 556.0
PYH3_k127_4244463_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006978 460.0
PYH3_k127_4244463_11 PFAM OmpA MotB domain protein K03640 - - 0.0000000000000000000000000000000000000005412 156.0
PYH3_k127_4244463_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000005347 144.0
PYH3_k127_4244463_13 - - - - 0.000000000000000000000000000000001237 130.0
PYH3_k127_4244463_14 Biopolymer transport protein ExbD/TolR K03560 - - 0.00000000000000000000000004503 111.0
PYH3_k127_4244463_15 energy transducer activity K03646,K03832 - - 0.000000000000000000000004354 112.0
PYH3_k127_4244463_16 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000000000000000007127 98.0
PYH3_k127_4244463_17 Diguanylate cyclase - - - 0.0000000000000112 86.0
PYH3_k127_4244463_19 all-trans-retinol 13,14-reductase activity - - - 0.000005878 59.0
PYH3_k127_4244463_2 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005817 377.0
PYH3_k127_4244463_3 cysteine protease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 350.0
PYH3_k127_4244463_4 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000261 334.0
PYH3_k127_4244463_5 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004922 338.0
PYH3_k127_4244463_6 TolB amino-terminal domain K03641 GO:0003674,GO:0005215,GO:0006810,GO:0008150,GO:0019534,GO:0022857,GO:0051179,GO:0051234,GO:0055085,GO:1901998 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001142 295.0
PYH3_k127_4244463_7 Formyl transferase K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001796 260.0
PYH3_k127_4244463_8 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004428 255.0
PYH3_k127_4244463_9 PFAM MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000005254 217.0
PYH3_k127_4248732_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454,K02504,K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 576.0
PYH3_k127_4248732_1 twitching motility protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005081 533.0
PYH3_k127_4248732_10 Prokaryotic N-terminal methylation motif - - - 0.0000003045 59.0
PYH3_k127_4248732_11 Pfam:N_methyl_2 - - - 0.000002846 60.0
PYH3_k127_4248732_2 response regulator K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 471.0
PYH3_k127_4248732_3 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 454.0
PYH3_k127_4248732_4 Type II secretion system (T2SS), protein F K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003151 402.0
PYH3_k127_4248732_5 His Kinase A (phosphoacceptor) domain K02668,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 325.0
PYH3_k127_4248732_6 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
PYH3_k127_4248732_7 histidine kinase, HAMP - - - 0.0000000000000000000000000000000000000000000000000000000000000000001623 256.0
PYH3_k127_4248732_8 Prokaryotic N-terminal methylation motif K02456,K02650,K02655 - - 0.0000000005743 66.0
PYH3_k127_4248732_9 Prokaryotic N-terminal methylation motif K02671 - - 0.00000003778 65.0
PYH3_k127_4255313_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002108 580.0
PYH3_k127_4255313_1 pyridine nucleotide-disulphide oxidoreductase dimerisation K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001814 295.0
PYH3_k127_4255313_2 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000005417 271.0
PYH3_k127_4255313_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002976 271.0
PYH3_k127_4255313_4 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domain of GcvH, an intermediate carrier during protein lipoylation K03800 - 6.3.1.20 0.000000000000000000000000000000000000000000002829 187.0
PYH3_k127_4257086_0 HI0933-like protein K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 303.0
PYH3_k127_4257086_1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.0000000000000000000000007749 113.0
PYH3_k127_4257086_2 cellulase activity K12287 - - 0.000000000000000001711 100.0
PYH3_k127_4257086_3 TonB-dependent receptor K02014,K02456,K02457,K02458,K10926,K10930,K10931 GO:0003674,GO:0005198,GO:0005575,GO:0005623,GO:0008150,GO:0009289,GO:0009405,GO:0009987,GO:0016043,GO:0030030,GO:0042995,GO:0044419,GO:0044464,GO:0051704,GO:0071840 - 0.000000000000007208 89.0
PYH3_k127_4257086_4 Amb_all K01728 - 4.2.2.2 0.00001353 58.0
PYH3_k127_4311775_0 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001428 272.0
PYH3_k127_4311775_1 Single-strand binding protein family K03111 - - 0.0000000000000000000000000000000000000000005106 161.0
PYH3_k127_4311775_2 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000004912 100.0
PYH3_k127_4311775_3 Binds together with S18 to 16S ribosomal RNA K02990 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000021 93.0
PYH3_k127_4311775_4 Predicted membrane protein (DUF2232) K16785,K16786,K16787 - - 0.0001284 54.0
PYH3_k127_4360756_0 Tetratricopeptide repeat - - - 0.0000000000000003345 88.0
PYH3_k127_4360756_1 Peptidase family M28 - - - 0.0000001906 63.0
PYH3_k127_4360756_2 - - - - 0.0000007104 57.0
PYH3_k127_4360756_3 - - - - 0.000001615 60.0
PYH3_k127_4459035_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 GO:0003674,GO:0005488,GO:0005543,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0019637,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001782 286.0
PYH3_k127_4459035_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000001301 222.0
PYH3_k127_4459035_10 Belongs to the UPF0434 family K09791 - - 0.00000000000003378 76.0
PYH3_k127_4459035_2 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000003005 215.0
PYH3_k127_4459035_3 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000122 183.0
PYH3_k127_4459035_4 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000002579 181.0
PYH3_k127_4459035_5 Protein of unknown function (DUF1009) K09949 - - 0.0000000000000000000000000000000000000000009682 173.0
PYH3_k127_4459035_6 Polynucleotide kinase 3 phosphatase K03273 - 3.1.3.82,3.1.3.83 0.000000000000000000000000000000000000000001891 179.0
PYH3_k127_4459035_7 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000002191 154.0
PYH3_k127_4459035_8 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000006546 143.0
PYH3_k127_4459035_9 Domain of unknown function (DUF374) K02527,K09778 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000005351 138.0
PYH3_k127_4557809_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 2.355e-262 823.0
PYH3_k127_4557809_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 582.0
PYH3_k127_4567522_0 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004414,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008374,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009092,GO:0009987,GO:0016053,GO:0016407,GO:0016413,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.3.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 462.0
PYH3_k127_4567522_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000002048 252.0
PYH3_k127_4567522_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000000000008236 229.0
PYH3_k127_4567522_3 TIGRFAM methionine biosynthesis protein MetW - - - 0.0000000000000000000000000000000000000000000000000000000001137 222.0
PYH3_k127_4567522_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000005303 144.0
PYH3_k127_4634130_0 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 7.048e-242 774.0
PYH3_k127_4634130_1 Belongs to the glycosyl hydrolase 57 family K03406,K16149 - 2.4.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 595.0
PYH3_k127_4634130_10 Domain of unknown function (DUF4912) K09942 - - 0.000000005347 66.0
PYH3_k127_4634130_2 Glycosyl hydrolase family 57 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 550.0
PYH3_k127_4634130_3 Domain of unknown function (DUF1925) K22451 - 2.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 517.0
PYH3_k127_4634130_4 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 488.0
PYH3_k127_4634130_5 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 411.0
PYH3_k127_4634130_6 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0000271,GO:0003674,GO:0003824,GO:0004373,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0008194,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0035251,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046527,GO:0055114,GO:0071704,GO:1901576 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 390.0
PYH3_k127_4634130_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 364.0
PYH3_k127_4634130_8 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03072,K03074,K12257 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004902 285.0
PYH3_k127_4634130_9 response regulator - - - 0.000000000000000000000000000000501 127.0
PYH3_k127_4915681_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K07788,K07789,K18138 - - 0.0 1189.0
PYH3_k127_4915681_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 2.729e-206 662.0
PYH3_k127_4915681_10 PFAM GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002514 293.0
PYH3_k127_4915681_11 GHKL domain K07315 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003133 292.0
PYH3_k127_4915681_12 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002423 274.0
PYH3_k127_4915681_13 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000002428 239.0
PYH3_k127_4915681_14 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000000000004394 222.0
PYH3_k127_4915681_15 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000003071 224.0
PYH3_k127_4915681_16 Bacterial protein of unknown function (DUF882) - - - 0.0000000000000000000000000000000000000000000000001432 185.0
PYH3_k127_4915681_17 3-beta hydroxysteroid dehydrogenase isomerase K21793 - - 0.00000000000000000000000000000000000000000000001488 193.0
PYH3_k127_4915681_18 Acyl-ACP thioesterase K01071 - 3.1.2.21 0.00000000000000000000000000000000000000000000004664 179.0
PYH3_k127_4915681_19 regulation of response to stimulus K01126,K21449 - 3.1.4.46 0.000000000000000000000000000000000000000000009079 187.0
PYH3_k127_4915681_2 TIGRFAM phosphoenolpyruvate-protein phosphotransferase K08484 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008002 616.0
PYH3_k127_4915681_20 Methyltransferase domain - - - 0.000000000000000000000000000000000000000001741 168.0
PYH3_k127_4915681_21 Flagellar hook protein flgE - - - 0.000000000000000000000000000000000000000004277 179.0
PYH3_k127_4915681_22 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000000006336 143.0
PYH3_k127_4915681_23 Phospholipase D. Active site motifs. K06131 - - 0.00000000000000000000000000000000001072 142.0
PYH3_k127_4915681_24 PAP2 superfamily - - - 0.000000000000000000000000000000004021 140.0
PYH3_k127_4915681_25 Smr domain - - - 0.00000000000000000000000000000002652 132.0
PYH3_k127_4915681_26 PFAM AzlC family protein - - - 0.00000000000000000000000000004337 130.0
PYH3_k127_4915681_27 CAAX protease self-immunity - - - 0.000000000000000001249 99.0
PYH3_k127_4915681_28 Putative prokaryotic signal transducing protein - - - 0.0000000000001549 73.0
PYH3_k127_4915681_29 Domain of unknown function DUF302 - - - 0.00000000002627 67.0
PYH3_k127_4915681_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005835 580.0
PYH3_k127_4915681_30 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000004826 70.0
PYH3_k127_4915681_4 Required for the activity of the bacterial periplasmic transport system of putrescine K11069 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0015695,GO:0015696,GO:0015846,GO:0015847,GO:0015848,GO:0019808,GO:0019809,GO:0019810,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0051179,GO:0051234,GO:0070405,GO:0071702,GO:0071705 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 415.0
PYH3_k127_4915681_5 TIGRFAM cysteine K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 352.0
PYH3_k127_4915681_6 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 347.0
PYH3_k127_4915681_7 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006515 314.0
PYH3_k127_4915681_8 SNARE associated Golgi protein K01077 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 308.0
PYH3_k127_4915681_9 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004433 321.0
PYH3_k127_4921838_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1230.0
PYH3_k127_4921838_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 4.571e-213 678.0
PYH3_k127_4921838_10 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006844 355.0
PYH3_k127_4921838_11 Mechanosensitive ion channel K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 337.0
PYH3_k127_4921838_12 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 328.0
PYH3_k127_4921838_13 regulation of RNA biosynthetic process - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009843 316.0
PYH3_k127_4921838_14 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K02945,K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000003273 265.0
PYH3_k127_4921838_15 Prephenate dehydratase K14170 GO:0003674,GO:0003824,GO:0004664,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006558,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009094,GO:0009095,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0019438,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902221,GO:1902223 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000000007053 262.0
PYH3_k127_4921838_16 Peptidase family S49 K04773 - - 0.00000000000000000000000000000000000000000000000000000000000002093 241.0
PYH3_k127_4921838_17 cytidylate kinase activity K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000005646 224.0
PYH3_k127_4921838_18 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000004961 218.0
PYH3_k127_4921838_19 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000011 202.0
PYH3_k127_4921838_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 2.034e-205 653.0
PYH3_k127_4921838_20 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000001152 213.0
PYH3_k127_4921838_21 DIM6 NTAB family - - - 0.00000000000000000000000000000000000000000000000000004583 194.0
PYH3_k127_4921838_22 TIGR00255 family - - - 0.0000000000000000000000000000000000000000000000007932 185.0
PYH3_k127_4921838_23 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000001337 171.0
PYH3_k127_4921838_24 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000006109 179.0
PYH3_k127_4921838_25 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 GO:0000217,GO:0000400,GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003678,GO:0003824,GO:0004386,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0007154,GO:0008150,GO:0008152,GO:0009314,GO:0009378,GO:0009379,GO:0009432,GO:0009605,GO:0009628,GO:0009987,GO:0009991,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017111,GO:0022607,GO:0031668,GO:0032392,GO:0032508,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0042802,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0048476,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051276,GO:0051289,GO:0051716,GO:0065003,GO:0071103,GO:0071496,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140097,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 0.00000000000000000000000000000000000388 152.0
PYH3_k127_4921838_26 Domain of unknown function (DUF4416) - - - 0.000000000000000000000000000000001243 138.0
PYH3_k127_4921838_27 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000004779 131.0
PYH3_k127_4921838_28 regulation of translation K05788 - - 0.000000000000000000000000000009136 121.0
PYH3_k127_4921838_29 - - - - 0.000000000000000000000003427 119.0
PYH3_k127_4921838_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 583.0
PYH3_k127_4921838_30 oligosaccharyl transferase activity - - - 0.00000000000000000000003006 115.0
PYH3_k127_4921838_31 peroxiredoxin activity - - - 0.00000000000000000000006685 113.0
PYH3_k127_4921838_32 phosphorelay signal transduction system - - - 0.000000000000000000004299 110.0
PYH3_k127_4921838_33 response regulator, receiver K03413 - - 0.00000000000000009307 95.0
PYH3_k127_4921838_34 photosynthesis K02453,K02660 - - 0.00000001103 67.0
PYH3_k127_4921838_35 Tetratricopeptide repeat - - - 0.000002371 57.0
PYH3_k127_4921838_36 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00002552 51.0
PYH3_k127_4921838_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 454.0
PYH3_k127_4921838_5 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001062 444.0
PYH3_k127_4921838_6 PFAM DAHP synthetase I KDSA K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 434.0
PYH3_k127_4921838_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 404.0
PYH3_k127_4921838_8 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962,K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 395.0
PYH3_k127_4921838_9 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004275 354.0
PYH3_k127_4945754_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1330.0
PYH3_k127_4945754_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 5.285e-261 822.0
PYH3_k127_4945754_10 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002766 283.0
PYH3_k127_4945754_11 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004642 288.0
PYH3_k127_4945754_12 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004546 291.0
PYH3_k127_4945754_13 Putative ATP-binding cassette K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006478 272.0
PYH3_k127_4945754_14 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000007682 199.0
PYH3_k127_4945754_15 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0006355,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032991,GO:0032993,GO:0033554,GO:0043565,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001141 3.4.21.88 0.000000000000000000000000000000000000000000000000063 185.0
PYH3_k127_4945754_16 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000001992 172.0
PYH3_k127_4945754_17 oxidation-reduction process K09022 - 3.5.99.10 0.000000000000000000000000000000000000007665 148.0
PYH3_k127_4945754_18 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.000000000000000000000000000000000000009425 155.0
PYH3_k127_4945754_19 Tetratricopeptide repeat - - - 0.0000000000000000000000001162 119.0
PYH3_k127_4945754_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.021e-216 692.0
PYH3_k127_4945754_20 Belongs to the bacterial ribosomal protein bL28 family K02902 GO:0003674,GO:0003735,GO:0005198 - 0.0000000000000000004316 90.0
PYH3_k127_4945754_21 Recombination protein O C terminal K03584 - - 0.00000000000000004356 95.0
PYH3_k127_4945754_23 - - - - 0.0000000000001147 75.0
PYH3_k127_4945754_24 Domain of unknown function (DUF4115) - - - 0.0000000000002345 81.0
PYH3_k127_4945754_25 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000006531 63.0
PYH3_k127_4945754_27 PFAM Chorismate mutase, type II - - - 0.0000004229 57.0
PYH3_k127_4945754_28 - - - - 0.00005459 55.0
PYH3_k127_4945754_29 Cytochrome c - - - 0.0005687 47.0
PYH3_k127_4945754_3 glycyl-tRNA aminoacylation K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 626.0
PYH3_k127_4945754_4 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 608.0
PYH3_k127_4945754_5 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 511.0
PYH3_k127_4945754_6 Belongs to the dGTPase family. Type 2 subfamily K01129 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 3.1.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005151 426.0
PYH3_k127_4945754_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 340.0
PYH3_k127_4945754_8 Belongs to the GPI family K01810 - 5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 312.0
PYH3_k127_4945754_9 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 293.0
PYH3_k127_4969319_0 Sensor sigma-54-dependent transcriptional regulator, GAF and GAF domain-containing - - - 3.424e-218 718.0
PYH3_k127_4969319_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007882 604.0
PYH3_k127_4969319_10 AMMECR1 K06990,K09141 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 347.0
PYH3_k127_4969319_11 Chitobiase/beta-hexosaminidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005715 358.0
PYH3_k127_4969319_12 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001041 293.0
PYH3_k127_4969319_13 Belongs to the arginase family K01480 - 3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000003052 271.0
PYH3_k127_4969319_14 xylanase chitin deacetylase K22278 - 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000006481 240.0
PYH3_k127_4969319_15 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000004869 213.0
PYH3_k127_4969319_16 Helix-turn-helix transcriptional regulator PuuR, cupin domain-containing - - - 0.00000000000000000000000000000000000000000000000000005373 193.0
PYH3_k127_4969319_17 PFAM Pyruvate kinase, alpha beta domain K09126 - - 0.0000000000000000000000000000000000000000000000000001381 192.0
PYH3_k127_4969319_18 Single cache domain 3 - - - 0.0000000000000000000000000000000000000000000000000009113 201.0
PYH3_k127_4969319_19 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000007569 186.0
PYH3_k127_4969319_2 Short chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008545 612.0
PYH3_k127_4969319_20 acetyltransferase K00661 - 2.3.1.79 0.0000000000000000000000000000000000000000000000000218 190.0
PYH3_k127_4969319_21 Polysaccharide deacetylase K22278 GO:0005575,GO:0005623,GO:0016020,GO:0042763,GO:0044464 3.5.1.104 0.0000000000000000000000000000000000000000000000002385 198.0
PYH3_k127_4969319_22 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000001314 180.0
PYH3_k127_4969319_23 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000002198 170.0
PYH3_k127_4969319_24 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 2.5.1.16 0.0000000000000000000000000000000000000002335 171.0
PYH3_k127_4969319_25 PFAM GGDEF domain containing protein - - - 0.000000000000000000000000000000000008746 148.0
PYH3_k127_4969319_26 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000002608 156.0
PYH3_k127_4969319_27 Stage II sporulation protein E (SpoIIE) - - - 0.0000000000000000000000000000000002516 151.0
PYH3_k127_4969319_28 - K16923 - - 0.000000000000000000000000000002511 141.0
PYH3_k127_4969319_29 Histidine kinase K07711 - 2.7.13.3 0.0000000000000000000000009832 110.0
PYH3_k127_4969319_3 COG1830 DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes K08321,K11645 - 2.3.1.245,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 434.0
PYH3_k127_4969319_30 PFAM FMN-binding domain K21559 - - 0.00000000000000000000319 107.0
PYH3_k127_4969319_31 TfoX N-terminal domain - - - 0.00000000000000004282 89.0
PYH3_k127_4969319_32 Psort location Cytoplasmic, score 8.96 - - - 0.00000000000002272 77.0
PYH3_k127_4969319_34 (FHA) domain - GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944,GO:0097159,GO:1901363 - 0.000000001797 69.0
PYH3_k127_4969319_4 Aminotransferase class IV K03342 - 2.6.1.85,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 442.0
PYH3_k127_4969319_5 carboxynorspermidine decarboxylase K13747 - 4.1.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002423 412.0
PYH3_k127_4969319_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 414.0
PYH3_k127_4969319_7 Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000176 385.0
PYH3_k127_4969319_8 PRTRC system protein D K18640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007261 344.0
PYH3_k127_4969319_9 Forkhead associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 339.0
PYH3_k127_497062_0 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000001917 201.0
PYH3_k127_497062_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000003109 166.0
PYH3_k127_497062_2 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000336 158.0
PYH3_k127_4987033_0 Domain of unknown function (DUF4445) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001063 258.0
PYH3_k127_4987033_1 SMART PAS domain containing protein - - - 0.0000000000001879 75.0
PYH3_k127_4987033_2 Solute carrier family 16, member 13 K08189 GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0012505,GO:0015075,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071944,GO:0098656,GO:1903825,GO:1905039 - 0.0000000000004379 81.0
PYH3_k127_5049218_0 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.000000000000000000000005012 113.0
PYH3_k127_5049218_1 UvrD/REP helicase N-terminal domain K16898 - 3.6.4.12 0.0000000004458 63.0
PYH3_k127_5054611_0 UvrD/REP helicase N-terminal domain - - - 1.239e-233 761.0
PYH3_k127_5054611_1 exonuclease activity K16899 - 3.6.4.12 3.776e-205 675.0
PYH3_k127_5054611_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 356.0
PYH3_k127_5054611_3 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.00000000000000000000000000000000000000000000000000000000000001658 224.0
PYH3_k127_5054611_4 PFAM aldo keto reductase K07079 - - 0.00004286 49.0
PYH3_k127_5105690_0 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 310.0
PYH3_k127_5105690_1 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004783 310.0
PYH3_k127_5105690_2 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001116 255.0
PYH3_k127_5105690_3 Belongs to the LarC family K09121 - 4.99.1.12 0.000000000000000000000000000000000000000000000000000000000000000000005311 250.0
PYH3_k127_5105690_4 PFAM 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000001218 237.0
PYH3_k127_5105690_5 diguanylate cyclase K02488 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000001591 194.0
PYH3_k127_5105690_6 Signal transducing histidine kinase, homodimeric domain K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000002184 169.0
PYH3_k127_5105690_7 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000032 145.0
PYH3_k127_5105690_8 CheC-like family K03410 - - 0.000000000000000000000000000001539 130.0
PYH3_k127_5107659_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1116.0
PYH3_k127_5107659_1 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 542.0
PYH3_k127_5107659_10 - - - - 0.00000000000000000000000000000001987 139.0
PYH3_k127_5107659_11 Uncharacterized protein conserved in bacteria (DUF2155) - - - 0.000000000000000000000000000001874 127.0
PYH3_k127_5107659_12 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000001955 113.0
PYH3_k127_5107659_13 cyclic nucleotide binding K10914 GO:0000166,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005515,GO:0006355,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0017076,GO:0019219,GO:0019222,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0045893,GO:0045935,GO:0046983,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902680,GO:1903506,GO:1903508,GO:2000112,GO:2001141 - 0.000000000000000004752 94.0
PYH3_k127_5107659_14 - - - - 0.000000000000001444 77.0
PYH3_k127_5107659_15 PFAM Bacterial regulatory proteins, crp family K10914 - - 0.000000000008377 75.0
PYH3_k127_5107659_17 cellulose binding K07279 - - 0.0005883 50.0
PYH3_k127_5107659_2 PFAM MOFRL domain protein K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003221 429.0
PYH3_k127_5107659_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 376.0
PYH3_k127_5107659_4 ADP-ribosylation factor family K06883 GO:0008150,GO:0032879,GO:0032880,GO:0050789,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009037 339.0
PYH3_k127_5107659_5 4Fe-4S binding domain K00124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002778 259.0
PYH3_k127_5107659_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.0000000000000000000000000000000000000000000000000000000000000001543 226.0
PYH3_k127_5107659_7 PFAM Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000009053 219.0
PYH3_k127_5107659_8 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000005687 215.0
PYH3_k127_5107659_9 Protein involved in formate dehydrogenase formation K02380 - - 0.00000000000000000000000000000000000002681 156.0
PYH3_k127_5110172_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 4.585e-290 911.0
PYH3_k127_5110172_1 Bifunctional purine biosynthesis protein PurH K00602 GO:0003674,GO:0003824,GO:0004643,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016742,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 567.0
PYH3_k127_5110172_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 319.0
PYH3_k127_5110172_3 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001739 280.0
PYH3_k127_5110172_4 PFAM Creatininase K01470 - 3.5.2.10 0.00000000000000000000000000000000000000000000000000000000000002567 222.0
PYH3_k127_5110172_5 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000008905 157.0
PYH3_k127_5110172_6 Belongs to the thioredoxin family K03671 - - 0.00000000000000000000000000000000000001574 147.0
PYH3_k127_5110172_7 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000004763 123.0
PYH3_k127_5110172_8 4Fe-4S binding domain - GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0022900,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 - 0.0000000000000000003095 93.0
PYH3_k127_5110172_9 Tetratricopeptide repeat - - - 0.00000000001448 78.0
PYH3_k127_513115_0 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008028 288.0
PYH3_k127_513115_1 ResB-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001042 287.0
PYH3_k127_513115_2 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K20881 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000004405 264.0
PYH3_k127_513115_3 YCII-related domain - - - 0.00000000000000000000000000007684 117.0
PYH3_k127_513115_4 Isoprenylcysteine carboxyl methyltransferase (ICMT) family - - - 0.00000004913 61.0
PYH3_k127_5187240_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007003 439.0
PYH3_k127_5187240_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009469 328.0
PYH3_k127_5187240_2 AAA domain, putative AbiEii toxin, Type IV TA system K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 312.0
PYH3_k127_5187240_3 NosL - - - 0.0000000000000000000000000000000000000004671 151.0
PYH3_k127_5187240_4 PFAM NosL family protein - - - 0.0000000000000000000000000000000000001736 150.0
PYH3_k127_5187240_5 - - - - 0.00000000000000000000003533 102.0
PYH3_k127_5187240_6 Tetratricopeptide repeat - - - 0.0000002959 63.0
PYH3_k127_520203_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000862 476.0
PYH3_k127_520203_1 response regulator K07712 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 442.0
PYH3_k127_520203_2 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006562 281.0
PYH3_k127_520203_3 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001235 266.0
PYH3_k127_520203_4 His Kinase A (phosphoacceptor) domain K02668,K07708,K07709 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000002049 222.0
PYH3_k127_520203_5 ABC-type transport system involved in resistance to organic solvents, ATPase component K02065 - - 0.00000000000000000000000000000000000000000000000000000003262 199.0
PYH3_k127_520203_6 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000002913 156.0
PYH3_k127_520203_7 nitric oxide dioxygenase activity - - - 0.0000000002217 64.0
PYH3_k127_5225291_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0000166,GO:0003674,GO:0003824,GO:0004175,GO:0004176,GO:0004222,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0008270,GO:0009056,GO:0009057,GO:0010468,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019222,GO:0019538,GO:0030145,GO:0030163,GO:0030554,GO:0031224,GO:0031226,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0035639,GO:0036094,GO:0040007,GO:0042623,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043273,GO:0044238,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0098796,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 1.355e-279 871.0
PYH3_k127_5225291_1 heavy metal translocating P-type ATPase K17686 - 3.6.3.54 1.351e-210 685.0
PYH3_k127_5225291_10 PFAM CBS domain - - - 0.00000000000000000000000000000000001977 148.0
PYH3_k127_5225291_11 PFAM YbbR family protein - - - 0.0000000000000000000000000000000086 135.0
PYH3_k127_5225291_12 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000005474 118.0
PYH3_k127_5225291_13 PFAM Uncharacterised P-loop hydrolase UPF0079 K06925 - - 0.000000000000000000000000003651 123.0
PYH3_k127_5225291_14 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.00002338 53.0
PYH3_k127_5225291_2 Aminotransferase class I and II K10206,K14261 GO:0003674,GO:0003824,GO:0004021,GO:0006082,GO:0006090,GO:0006520,GO:0006522,GO:0006523,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009078,GO:0009079,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0019272,GO:0019752,GO:0030632,GO:0032787,GO:0042851,GO:0042852,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046144,GO:0046145,GO:0046394,GO:0046416,GO:0046436,GO:0046437,GO:0047635,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000362 565.0
PYH3_k127_5225291_3 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 467.0
PYH3_k127_5225291_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004073,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006549,GO:0006553,GO:0006555,GO:0006566,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009081,GO:0009082,GO:0009085,GO:0009086,GO:0009088,GO:0009089,GO:0009097,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0019752,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 428.0
PYH3_k127_5225291_5 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006653 396.0
PYH3_k127_5225291_6 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 327.0
PYH3_k127_5225291_7 Pterin binding enzyme K00796,K13941 - 2.5.1.15,2.7.6.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 302.0
PYH3_k127_5225291_8 Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria K18672 - 2.7.7.85 0.000000000000000000000000000000000000000000000000000000000000000000004514 250.0
PYH3_k127_5225291_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000006768 213.0
PYH3_k127_5251900_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 531.0
PYH3_k127_5251900_1 COG0618 Exopolyphosphatase-related proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 297.0
PYH3_k127_5251900_2 Belongs to the peptidase M50B family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004836 291.0
PYH3_k127_5251900_3 Pfam Anion-transporting ATPase K01551,K19171 - 3.6.3.16 0.000000000000000000000000000000000000000000000000000000000000000007249 235.0
PYH3_k127_5251900_4 PFAM heat shock protein DnaJ domain protein - - - 0.00000000000000000000000000000000000000004742 162.0
PYH3_k127_5251900_5 PFAM ApbE family K09740 - - 0.00000000005326 75.0
PYH3_k127_5260782_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 539.0
PYH3_k127_5260782_1 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 409.0
PYH3_k127_5260782_10 Coenzyme PQQ synthesis protein D (PqqD) - - - 0.0000000000000002013 85.0
PYH3_k127_5260782_11 peptidyl-tyrosine sulfation - - - 0.0001892 51.0
PYH3_k127_5260782_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 338.0
PYH3_k127_5260782_3 ABC transporter, phosphonate, periplasmic substrate-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002903 288.0
PYH3_k127_5260782_4 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002474 272.0
PYH3_k127_5260782_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000001318 246.0
PYH3_k127_5260782_6 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000008134 237.0
PYH3_k127_5260782_7 HEAT repeat - - - 0.0000000000000000000000000000000000000001239 162.0
PYH3_k127_5260782_9 ResB-like family - - - 0.000000000000000000000000000000004777 141.0
PYH3_k127_5287481_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 1.826e-243 771.0
PYH3_k127_5287481_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 3.084e-219 699.0
PYH3_k127_5287481_2 PFAM peptidase M16 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000675 369.0
PYH3_k127_5287481_3 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000001336 215.0
PYH3_k127_5287481_4 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000001089 193.0
PYH3_k127_5287481_5 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006139,GO:0006378,GO:0006396,GO:0006397,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016020,GO:0016043,GO:0016070,GO:0016071,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0031123,GO:0031124,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043631,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000001891 127.0
PYH3_k127_5287481_6 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000001993 95.0
PYH3_k127_5287481_7 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000004446 97.0
PYH3_k127_5323426_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1156.0
PYH3_k127_5323426_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007708 389.0
PYH3_k127_5323426_2 PFAM Transposase IS200 like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 320.0
PYH3_k127_5323426_3 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 302.0
PYH3_k127_5323426_4 Peptidase U62 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002707 258.0
PYH3_k127_5323426_5 PFAM peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000003129 235.0
PYH3_k127_5323426_6 PFAM Acetyltransferase (GNAT) family K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000002183 203.0
PYH3_k127_5323426_7 Ribosomal RNA methyltransferase RrmJ FtsJ K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000001575 102.0
PYH3_k127_5323426_8 Two-component system response regulator K07715 GO:0000156,GO:0000160,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0001130,GO:0001150,GO:0001151,GO:0001158,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009891,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0023052,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0035326,GO:0035556,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0045893,GO:0045935,GO:0046483,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051252,GO:0051254,GO:0051716,GO:0060089,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902680,GO:1903506,GO:1903508,GO:1990837,GO:2000112,GO:2001141 - 0.000000000000000001013 94.0
PYH3_k127_5340559_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 444.0
PYH3_k127_5340559_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 421.0
PYH3_k127_5340559_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000004438 215.0
PYH3_k127_5340559_3 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000008976 177.0
PYH3_k127_5340559_4 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.0000000000000000000000000005626 127.0
PYH3_k127_5340559_5 YceI-like domain - - - 0.00000000000000000000000001778 115.0
PYH3_k127_5340559_6 Histidine kinase - - - 0.00000000000000000000000002675 115.0
PYH3_k127_5340559_7 Cytochrome b5-like Heme/Steroid binding domain - - - 0.000000000000000008817 89.0
PYH3_k127_5340559_9 Thioredoxin-like - - - 0.0000000000007173 75.0
PYH3_k127_538093_0 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 1.878e-210 680.0
PYH3_k127_538093_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000412 592.0
PYH3_k127_538093_10 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007523 267.0
PYH3_k127_538093_11 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001843 256.0
PYH3_k127_538093_12 Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ) K00878 - 2.7.1.50 0.00000000000000000000000000000000000000000000000000000000000000000000000004487 258.0
PYH3_k127_538093_13 Tetratricopeptide TPR_2 repeat protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001271 250.0
PYH3_k127_538093_14 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000007469 242.0
PYH3_k127_538093_15 Belongs to the pseudouridine synthase RsuA family K06178,K06183 - 5.4.99.19,5.4.99.22 0.000000000000000000000000000000000000000000000000000000000000003256 228.0
PYH3_k127_538093_16 Domain of unknown function (DUF4388) - - - 0.00000000000000000000000000000000000000000000000000000000000002627 233.0
PYH3_k127_538093_17 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000002359 226.0
PYH3_k127_538093_18 PFAM peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000009879 203.0
PYH3_k127_538093_19 Curli production assembly transport component CsgG K04087 - - 0.000000000000000000000000000000000000000000000000000000308 207.0
PYH3_k127_538093_2 CBS domain containing protein K00974 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008318 554.0
PYH3_k127_538093_20 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000000000000000000000000000000000000000003911 200.0
PYH3_k127_538093_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000002453 190.0
PYH3_k127_538093_22 - - - - 0.0000000000000000000000000000000000000000000002252 178.0
PYH3_k127_538093_23 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000006556 174.0
PYH3_k127_538093_24 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.000000000000000000000000000000000000000003397 164.0
PYH3_k127_538093_25 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000003792 158.0
PYH3_k127_538093_26 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000001406 151.0
PYH3_k127_538093_27 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000000000001373 139.0
PYH3_k127_538093_28 hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000106 136.0
PYH3_k127_538093_29 Cytochrome b/b6/petB K03620 - - 0.00000000000000000000000000003634 124.0
PYH3_k127_538093_3 TIGRFAM tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004489 401.0
PYH3_k127_538093_30 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000006014 124.0
PYH3_k127_538093_31 Histidine kinase - - - 0.000000000000000000005344 102.0
PYH3_k127_538093_32 PFAM Pentapeptide repeats (8 copies) - - - 0.00000000000000000001441 106.0
PYH3_k127_538093_33 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000007135 93.0
PYH3_k127_538093_34 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000001237 81.0
PYH3_k127_538093_35 HD domain - - - 0.0000000000000001583 84.0
PYH3_k127_538093_36 FHA Domain - - - 0.000000000000001543 89.0
PYH3_k127_538093_37 metal-dependent phosphoesterases (PHP family) - - - 0.000000000003094 75.0
PYH3_k127_538093_38 Sensor diguanylate cyclase, GAF domain-containing - - - 0.00000000003314 76.0
PYH3_k127_538093_39 VanZ like family - - - 0.0000006197 60.0
PYH3_k127_538093_4 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 404.0
PYH3_k127_538093_40 Mitochondrial domain of unknown function (DUF1713) - - - 0.00003666 47.0
PYH3_k127_538093_5 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000555 398.0
PYH3_k127_538093_6 TIGRFAM hydrogenase (NiFe) small subunit (hydA) K06282 - 1.12.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008958 394.0
PYH3_k127_538093_7 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 390.0
PYH3_k127_538093_8 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000798 398.0
PYH3_k127_538093_9 AIR synthase related protein, C-terminal domain K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002571 377.0
PYH3_k127_5415688_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 3.599e-225 728.0
PYH3_k127_5415688_1 Signal transduction histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 446.0
PYH3_k127_5415688_10 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000000000005325 145.0
PYH3_k127_5415688_11 COG1392 Phosphate transport regulator (distant homolog of PhoU) K07220 - - 0.000000000000000000000000000005512 128.0
PYH3_k127_5415688_2 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 418.0
PYH3_k127_5415688_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 394.0
PYH3_k127_5415688_4 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002057 402.0
PYH3_k127_5415688_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008325 362.0
PYH3_k127_5415688_6 TIGRFAM phosphate ABC transporter K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 366.0
PYH3_k127_5415688_7 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002841 348.0
PYH3_k127_5415688_8 cheY-homologous receiver domain K07657 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
PYH3_k127_5415688_9 PhoU domain K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000004701 226.0
PYH3_k127_5449449_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 2.106e-232 735.0
PYH3_k127_5449449_1 Isocitrate/isopropylmalate dehydrogenase K00031 GO:0003674,GO:0003824,GO:0003862,GO:0004448,GO:0004450,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0022900,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 1.712e-228 714.0
PYH3_k127_5449449_10 TIGRFAM hydro-lyases, Fe-S type, tartrate fumarate subfamily, alpha region K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000926 362.0
PYH3_k127_5449449_11 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 343.0
PYH3_k127_5449449_12 potassium uptake protein TrkH K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 327.0
PYH3_k127_5449449_13 Hydro-lyase, Fe-S type, tartrate fumarate subfamily, beta subunit K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 258.0
PYH3_k127_5449449_14 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000332 258.0
PYH3_k127_5449449_15 ADP-ribosylation factor family K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000009517 239.0
PYH3_k127_5449449_16 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000007702 218.0
PYH3_k127_5449449_17 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000003562 216.0
PYH3_k127_5449449_18 Competence protein K02238 - - 0.000000000000000000000000000002204 139.0
PYH3_k127_5449449_19 - - - - 0.00000000000000000000001177 114.0
PYH3_k127_5449449_2 succinate dehydrogenase, flavoprotein subunit K00239 GO:0000104,GO:0000166,GO:0001539,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006113,GO:0006928,GO:0006950,GO:0006974,GO:0006996,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016043,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022607,GO:0022900,GO:0030030,GO:0030031,GO:0032991,GO:0033554,GO:0036094,GO:0040011,GO:0043167,GO:0043168,GO:0043436,GO:0044085,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0044780,GO:0044781,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045283,GO:0045284,GO:0045333,GO:0048037,GO:0048870,GO:0050660,GO:0050662,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0055114,GO:0070469,GO:0070470,GO:0070925,GO:0071704,GO:0071840,GO:0071944,GO:0071949,GO:0071973,GO:0072350,GO:0097159,GO:0097588,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 7.895e-201 640.0
PYH3_k127_5449449_20 succinate dehydrogenase K00241 - - 0.000000000000000000001971 97.0
PYH3_k127_5449449_21 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.0000000000000000003222 91.0
PYH3_k127_5449449_22 GIY-YIG catalytic domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.00000000000000002042 89.0
PYH3_k127_5449449_23 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000001873 69.0
PYH3_k127_5449449_24 His Kinase A (phosphoacceptor) domain - - - 0.0000002084 64.0
PYH3_k127_5449449_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 495.0
PYH3_k127_5449449_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 472.0
PYH3_k127_5449449_5 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002565 475.0
PYH3_k127_5449449_6 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 456.0
PYH3_k127_5449449_7 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 438.0
PYH3_k127_5449449_8 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 410.0
PYH3_k127_5449449_9 PFAM thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 395.0
PYH3_k127_5469856_0 GMP synthase C terminal domain K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009021 372.0
PYH3_k127_5469856_1 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 288.0
PYH3_k127_5469856_2 TIGRFAM Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 264.0
PYH3_k127_5469856_3 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000006795 147.0
PYH3_k127_5542352_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 604.0
PYH3_k127_5542352_1 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.00000000000000000000000000000000000000000000000000000000000000000001733 235.0
PYH3_k127_5542352_2 ATP cone domain K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000005207 224.0
PYH3_k127_5542352_3 Part of a membrane complex involved in electron transport K03615 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000001062 191.0
PYH3_k127_5542352_4 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.0000000000000000000000000000000000000000000000000001709 189.0
PYH3_k127_5542352_5 ribose 5-phosphate isomerase B K01808 - 5.3.1.6 0.0000000000000000000000000000000000000000000000003564 180.0
PYH3_k127_5553564_0 Winged helix-turn helix - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 389.0
PYH3_k127_5553564_1 PFAM ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 340.0
PYH3_k127_5553564_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001616 286.0
PYH3_k127_5553564_3 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000007147 207.0
PYH3_k127_5553564_4 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000287 185.0
PYH3_k127_5553564_5 PFAM Respiratory-chain NADH dehydrogenase 24 Kd subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000003328 176.0
PYH3_k127_5669873_0 PFAM NAD-dependent epimerase dehydratase K08678 - 4.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 467.0
PYH3_k127_5669873_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 412.0
PYH3_k127_5669873_2 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003319 347.0
PYH3_k127_5669873_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 315.0
PYH3_k127_5669873_4 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005643 321.0
PYH3_k127_5669873_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 303.0
PYH3_k127_5669873_6 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000002102 178.0
PYH3_k127_5669873_7 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000004487 166.0
PYH3_k127_5669873_8 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000004938 115.0
PYH3_k127_5669873_9 cell redox homeostasis - - - 0.000000000000000000000296 109.0
PYH3_k127_5726079_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006523 571.0
PYH3_k127_5726079_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 569.0
PYH3_k127_5726079_10 acetate kinase activity K00925 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 355.0
PYH3_k127_5726079_11 Electron transfer flavoprotein K03521 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016020,GO:0016491,GO:0022900,GO:0030312,GO:0040007,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 340.0
PYH3_k127_5726079_12 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 329.0
PYH3_k127_5726079_13 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006749 333.0
PYH3_k127_5726079_14 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 321.0
PYH3_k127_5726079_15 TIGRFAM malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 334.0
PYH3_k127_5726079_16 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016746,GO:0016747,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004689 325.0
PYH3_k127_5726079_17 prohibitin homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 312.0
PYH3_k127_5726079_18 Udp N-acetylglucosamine O-acyltransferase; Domain 2 K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003081 310.0
PYH3_k127_5726079_19 PFAM Histone deacetylase K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 301.0
PYH3_k127_5726079_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004547 518.0
PYH3_k127_5726079_20 Phosphonate ABC transporter, periplasmic K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 296.0
PYH3_k127_5726079_21 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001134 280.0
PYH3_k127_5726079_22 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000001079 269.0
PYH3_k127_5726079_23 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006243 269.0
PYH3_k127_5726079_24 PAS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003936 273.0
PYH3_k127_5726079_25 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004946 258.0
PYH3_k127_5726079_26 tRNA methylthiotransferase YqeV K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000001165 259.0
PYH3_k127_5726079_27 FeS cluster assembly scaffold protein NifU K04488 - - 0.0000000000000000000000000000000000000000000000000000000000005494 212.0
PYH3_k127_5726079_28 OmpA family K02557 - - 0.0000000000000000000000000000000000000000000000000000000001458 217.0
PYH3_k127_5726079_29 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000002864 194.0
PYH3_k127_5726079_3 surface antigen (D15) K07277 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002562 484.0
PYH3_k127_5726079_30 Zn-dependent hydrolases of the - - - 0.000000000000000000000000000000000000000000000000006563 194.0
PYH3_k127_5726079_31 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000002075 150.0
PYH3_k127_5726079_32 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000008812 119.0
PYH3_k127_5726079_33 Mut7-C ubiquitin K09122 - - 0.00000000000000000000000001507 115.0
PYH3_k127_5726079_34 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000004822 108.0
PYH3_k127_5726079_35 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008289,GO:0008610,GO:0008654,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016053,GO:0019637,GO:0019752,GO:0019842,GO:0031177,GO:0032787,GO:0033218,GO:0036094,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046493,GO:0048037,GO:0050896,GO:0051192,GO:0071704,GO:0072330,GO:0072341,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.00000000000000000002026 103.0
PYH3_k127_5726079_37 acylphosphatase activity K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.0000000000000000004198 89.0
PYH3_k127_5726079_38 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0003674,GO:0003735,GO:0005198 - 0.00000000000000001933 83.0
PYH3_k127_5726079_39 Protein of unknown function (DUF2905) - - - 0.0000000000000001575 83.0
PYH3_k127_5726079_4 Electron transfer flavoprotein K03522,K22432 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009055,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016491,GO:0019395,GO:0019752,GO:0022900,GO:0030258,GO:0032787,GO:0033539,GO:0034440,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0071704,GO:0072329,GO:0097159,GO:1901265,GO:1901363,GO:1901575 1.3.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002455 449.0
PYH3_k127_5726079_40 Outer membrane protein (OmpH-like) K06142 - - 0.00000000009055 70.0
PYH3_k127_5726079_41 Protein of unknown function (DUF1009) K09949 GO:0003674,GO:0003824,GO:0005975,GO:0006629,GO:0006643,GO:0006644,GO:0006664,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0008758,GO:0009058,GO:0009245,GO:0009247,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0019637,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0046467,GO:0046493,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901576,GO:1903509 - 0.0000001343 59.0
PYH3_k127_5726079_42 Helix-hairpin-helix motif K02237 - - 0.00001152 56.0
PYH3_k127_5726079_43 - - - - 0.0002558 52.0
PYH3_k127_5726079_5 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000181 434.0
PYH3_k127_5726079_6 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 411.0
PYH3_k127_5726079_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 400.0
PYH3_k127_5726079_8 TIGRFAM Lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 384.0
PYH3_k127_5726079_9 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000423 364.0
PYH3_k127_5921485_0 Predicted membrane protein (DUF2157) - - - 0.0000000000000000000000000000000003551 151.0
PYH3_k127_5921485_1 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000007307 114.0
PYH3_k127_5921485_2 GDYXXLXY protein - - - 0.00000004187 64.0
PYH3_k127_6139303_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 6.651e-294 923.0
PYH3_k127_6139303_1 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003916 278.0
PYH3_k127_6139303_2 Response regulator receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000005641 177.0
PYH3_k127_6139303_3 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000001824 177.0
PYH3_k127_6164679_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 1.876e-293 919.0
PYH3_k127_6164679_1 Natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000092 310.0
PYH3_k127_6164679_2 MgtE intracellular N domain K02000,K05847 - 3.6.3.32 0.0000000000000000000000000000000000000000000000000008538 205.0
PYH3_k127_6196821_0 pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for K15987 - 3.6.1.1 1.29e-262 824.0
PYH3_k127_6196821_1 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 3.127e-235 755.0
PYH3_k127_6196821_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.0000000000000000000000000000000000000000000000000000005376 203.0
PYH3_k127_6196821_11 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000482 203.0
PYH3_k127_6196821_12 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000001586 192.0
PYH3_k127_6196821_13 Peptidase family M23 K21471 - - 0.000000000000000000000000000000000000000000000006575 189.0
PYH3_k127_6196821_14 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000001272 173.0
PYH3_k127_6196821_15 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000004662 166.0
PYH3_k127_6196821_16 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000183 162.0
PYH3_k127_6196821_17 Could be involved in septation K06412 - - 0.00000000000000000000000000000001653 136.0
PYH3_k127_6196821_18 - - - - 0.0000000000000000000000003879 109.0
PYH3_k127_6196821_19 protein secretion K03116 - - 0.000000000000000003419 85.0
PYH3_k127_6196821_2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.792e-230 720.0
PYH3_k127_6196821_20 regulatory protein, arsR - - - 0.00000000000000000605 86.0
PYH3_k127_6196821_21 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.000159 53.0
PYH3_k127_6196821_3 PFAM Aminotransferase class I and II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 474.0
PYH3_k127_6196821_4 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 439.0
PYH3_k127_6196821_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008121 419.0
PYH3_k127_6196821_6 Glycoprotease family K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 311.0
PYH3_k127_6196821_7 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009247 257.0
PYH3_k127_6196821_8 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000003628 246.0
PYH3_k127_6196821_9 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000003162 225.0
PYH3_k127_6210919_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 545.0
PYH3_k127_6210919_1 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 482.0
PYH3_k127_6210919_2 OST-HTH/LOTUS domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004368 333.0
PYH3_k127_6210919_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 324.0
PYH3_k127_6210919_4 Domain of unknown function (DUF814) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 312.0
PYH3_k127_6210919_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000001241 268.0
PYH3_k127_6210919_6 PFAM GGDEF domain containing protein, response regulator receiver - - - 0.00000000000000000000000000000000001422 148.0
PYH3_k127_6210919_7 THIoesterase K18700 - 3.1.2.29 0.00000000000000003751 89.0
PYH3_k127_6210919_8 Glutaredoxin K03676 - - 0.000000002038 59.0
PYH3_k127_6237632_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 392.0
PYH3_k127_6237632_1 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001198 284.0
PYH3_k127_6237632_2 Doxx family K15977 - - 0.0000000000000000000000000000000000000000000139 166.0
PYH3_k127_6253189_0 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 523.0
PYH3_k127_6253189_1 NeuB family K03856,K04516 - 2.5.1.54,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002316 473.0
PYH3_k127_6253189_10 Response regulator receiver K02485 - - 0.000000000000008687 81.0
PYH3_k127_6253189_11 Tetratricopeptide repeat - - - 0.000000000009416 78.0
PYH3_k127_6253189_12 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.00000002735 61.0
PYH3_k127_6253189_13 Tetratricopeptide repeat - - - 0.000001078 62.0
PYH3_k127_6253189_2 Parallel beta-helix repeats - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 463.0
PYH3_k127_6253189_3 PFAM Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 434.0
PYH3_k127_6253189_4 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009379 240.0
PYH3_k127_6253189_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000004803 185.0
PYH3_k127_6253189_6 Flagellar hook protein flgE - - - 0.000000000000000000000000000002854 140.0
PYH3_k127_6253189_7 Transporter, MotA TolQ ExbB proton channel family protein K03561 - - 0.0000000000000000000000000003889 121.0
PYH3_k127_6253189_8 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.00000000000000000000000008358 110.0
PYH3_k127_6253189_9 Tetratricopeptide repeat - - - 0.000000000000000000000004433 119.0
PYH3_k127_6356897_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 402.0
PYH3_k127_6356897_1 - - - - 0.0001033 54.0
PYH3_k127_6356897_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0003618 51.0
PYH3_k127_6360575_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002094 564.0
PYH3_k127_6360575_1 PFAM ResB family protein K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006122 328.0
PYH3_k127_6360575_2 TIGRFAM cytochrome c-type biogenesis protein CcsB - - - 0.00000000000000000000000000000000000000000006205 177.0
PYH3_k127_6360575_3 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000002556 157.0
PYH3_k127_6360575_4 Class III cytochrome C family - - - 0.00000000004492 69.0
PYH3_k127_6360575_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0002535 46.0
PYH3_k127_6374976_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.938e-234 741.0
PYH3_k127_6374976_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003858 359.0
PYH3_k127_6374976_2 Belongs to the FPP GGPP synthase family K00795,K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001563 298.0
PYH3_k127_6374976_3 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000119 316.0
PYH3_k127_6374976_4 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000002627 67.0
PYH3_k127_6445994_0 PFAM glutamine synthetase catalytic region K01915 - 6.3.1.2 5.434e-237 741.0
PYH3_k127_6445994_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 GO:0003674,GO:0003824,GO:0004812,GO:0004822,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006428,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.5 4.37e-196 624.0
PYH3_k127_6445994_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000028 243.0
PYH3_k127_6445994_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000001285 218.0
PYH3_k127_6445994_4 Belongs to the P(II) protein family K04751 - - 0.0000000000000000000000000000000000000000000000000008263 186.0
PYH3_k127_6445994_5 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000001874 144.0
PYH3_k127_6445994_6 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000006695 138.0
PYH3_k127_6510623_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 497.0
PYH3_k127_6510623_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 427.0
PYH3_k127_6510623_2 Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.000000000000001229 76.0
PYH3_k127_6535318_0 Threonyl and Alanyl tRNA synthetase second additional domain K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 3.149e-273 853.0
PYH3_k127_6535318_1 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005737 512.0
PYH3_k127_6535318_10 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000004686 167.0
PYH3_k127_6535318_11 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000004438 137.0
PYH3_k127_6535318_12 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.00000000000000000000000000002312 119.0
PYH3_k127_6535318_13 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000001064 114.0
PYH3_k127_6535318_14 PFAM S23 ribosomal protein - - - 0.00000000000000000001424 104.0
PYH3_k127_6535318_15 Ribosomal protein L35 K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000003428 91.0
PYH3_k127_6535318_16 Helix-turn-helix domain - - - 0.0000000000001579 79.0
PYH3_k127_6535318_17 Chain length determinant protein K16692 - - 0.00000007907 61.0
PYH3_k127_6535318_2 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 432.0
PYH3_k127_6535318_3 Helix-hairpin-helix domain K04477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 332.0
PYH3_k127_6535318_4 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 291.0
PYH3_k127_6535318_5 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000001627 265.0
PYH3_k127_6535318_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000002286 261.0
PYH3_k127_6535318_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000198 204.0
PYH3_k127_6535318_8 Secreted repeat of unknown function - - - 0.00000000000000000000000000000000000000000006978 165.0
PYH3_k127_6535318_9 Polysaccharide biosynthesis/export protein K01991 - - 0.000000000000000000000000000000000000000000459 170.0
PYH3_k127_6595208_0 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000002212 184.0
PYH3_k127_6595208_1 Biopolymer transport protein ExbD/TolR - - - 0.0000000000000000000000000000000000007685 146.0
PYH3_k127_6595208_2 PFAM MotA TolQ ExbB proton channel K03561 - - 0.000000000000000000000000000000002786 130.0
PYH3_k127_6595208_3 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000003992 129.0
PYH3_k127_6595208_4 Bacterial regulatory proteins, crp family K10914 - - 0.00000000007033 68.0
PYH3_k127_6595208_5 Biopolymer transport protein ExbD/TolR - - - 0.000000000323 68.0
PYH3_k127_6595208_6 iron ion homeostasis - - - 0.00002146 55.0
PYH3_k127_6595208_7 fumarate reductase K00239 - 1.3.5.1,1.3.5.4 0.00004236 55.0
PYH3_k127_6616285_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 549.0
PYH3_k127_6616285_1 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 354.0
PYH3_k127_6616285_2 regulatory protein IclR - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 303.0
PYH3_k127_6616285_3 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000002628 269.0
PYH3_k127_6616285_4 regulatory protein IclR - - - 0.000000000000000000000000000000000000000000000000000000000000000001235 240.0
PYH3_k127_6616285_5 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000001042 174.0
PYH3_k127_6616285_6 COG COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00180 - 1.2.7.8 0.000000000000000000000001478 111.0
PYH3_k127_6616285_7 UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase SEC K09667 - 2.4.1.255 0.000000000000000000008184 101.0
PYH3_k127_6637634_0 PFAM ferredoxin-dependent glutamate synthase - - - 9.159e-286 883.0
PYH3_k127_6637634_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 7.394e-239 753.0
PYH3_k127_6637634_10 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000002728 149.0
PYH3_k127_6637634_11 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000007691 149.0
PYH3_k127_6637634_12 SMART regulatory protein ArsR - - - 0.00000000000000000000000000000832 122.0
PYH3_k127_6637634_13 oligosaccharyl transferase activity - - - 0.000000000000000000000000009863 126.0
PYH3_k127_6637634_14 - - - - 0.0000000000000000000000003638 121.0
PYH3_k127_6637634_15 Thioredoxin domain - - - 0.000000000000000000000004033 103.0
PYH3_k127_6637634_2 Predicted permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 559.0
PYH3_k127_6637634_3 Sodium Bile acid symporter family K03325,K03741 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015104,GO:0015105,GO:0015291,GO:0015297,GO:0015318,GO:0015698,GO:0015699,GO:0015700,GO:0016020,GO:0022804,GO:0022857,GO:0034220,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656 1.20.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 477.0
PYH3_k127_6637634_4 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003261 346.0
PYH3_k127_6637634_5 peptide catabolic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 328.0
PYH3_k127_6637634_6 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005033 284.0
PYH3_k127_6637634_7 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000006221 244.0
PYH3_k127_6637634_8 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000001542 220.0
PYH3_k127_6637634_9 Cytochrome C biogenesis protein - - - 0.00000000000000000000000000000000000000000000000000000007188 203.0
PYH3_k127_6648227_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 3.486e-203 639.0
PYH3_k127_6648227_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 531.0
PYH3_k127_6648227_10 PTS system sorbose subfamily IIB component K02794 - 2.7.1.191 0.00000000000000000000001692 116.0
PYH3_k127_6648227_11 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000006803 115.0
PYH3_k127_6648227_12 system, mannose fructose sorbose family IID component K02795,K02796,K10986 - - 0.0000000000000000000001236 111.0
PYH3_k127_6648227_13 PTS HPr component phosphorylation site K11189 - - 0.0000000000003163 83.0
PYH3_k127_6648227_14 Permease, YjgP YjgQ - - - 0.00000000002908 75.0
PYH3_k127_6648227_15 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.000000001101 65.0
PYH3_k127_6648227_16 PA14 domain - - - 0.00000001523 64.0
PYH3_k127_6648227_17 PTS system sorbose-specific iic component K02795 - - 0.000002024 59.0
PYH3_k127_6648227_18 PFAM CheW domain protein K03408 - - 0.0001095 50.0
PYH3_k127_6648227_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 437.0
PYH3_k127_6648227_3 PFAM ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003251 299.0
PYH3_k127_6648227_4 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005615 259.0
PYH3_k127_6648227_5 - - - - 0.00000000000000000000000000000000000000000000000002162 190.0
PYH3_k127_6648227_6 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000000000000002083 173.0
PYH3_k127_6648227_7 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.000000000000000000000000000000000000003042 153.0
PYH3_k127_6648227_8 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000001999 151.0
PYH3_k127_6648227_9 PTS system fructose IIA component K02793 - 2.7.1.191 0.0000000000000000000000000000002217 127.0
PYH3_k127_6679425_0 PFAM Integrase catalytic region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 507.0
PYH3_k127_6679425_1 glycosyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 391.0
PYH3_k127_6679425_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005699 294.0
PYH3_k127_6679425_3 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003964 280.0
PYH3_k127_6679425_4 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004827 254.0
PYH3_k127_6679425_5 PFAM glycosyl transferase family 9 K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000109 267.0
PYH3_k127_6679425_6 lipopolysaccharide heptosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000003683 239.0
PYH3_k127_6679425_7 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000003991 231.0
PYH3_k127_6693188_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01533 - 3.6.3.4 7.521e-283 886.0
PYH3_k127_6693188_1 - - - - 0.000000000000000000001975 100.0
PYH3_k127_6693188_2 - - - - 0.0000000000000147 80.0
PYH3_k127_6693188_3 Short C-terminal domain K08982 - - 0.000000000005994 69.0
PYH3_k127_6739617_0 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 552.0
PYH3_k127_6739617_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000004543 168.0
PYH3_k127_6739617_2 Belongs to the SUA5 family K07566 - 2.7.7.87 0.0000000000000000000000000000000000209 149.0
PYH3_k127_6774186_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 2.299e-226 720.0
PYH3_k127_6774186_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 437.0
PYH3_k127_6774186_10 Catalyzes the 2'-O methylation of guanosine at position 18 in tRNA K00556 - 2.1.1.34 0.00000000000000000000000000000000003254 148.0
PYH3_k127_6774186_11 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000000000008698 141.0
PYH3_k127_6774186_12 alkyl hydroperoxide reductase activity - - - 0.00000000001044 67.0
PYH3_k127_6774186_13 Thioredoxin domain - - - 0.000003689 56.0
PYH3_k127_6774186_14 - - - - 0.0003146 50.0
PYH3_k127_6774186_2 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001957 217.0
PYH3_k127_6774186_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000001438 207.0
PYH3_k127_6774186_4 PFAM iron dependent repressor K03709 - - 0.000000000000000000000000000000000000000000000000000006011 199.0
PYH3_k127_6774186_5 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.00000000000000000000000000000000000000000000001693 190.0
PYH3_k127_6774186_6 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000003752 169.0
PYH3_k127_6774186_7 Belongs to the carbohydrate kinase PfkB family K21056 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0019200,GO:0044237,GO:0044238,GO:0044262,GO:0044424,GO:0044464,GO:0046835,GO:0071704 2.7.1.212 0.000000000000000000000000000000000000004095 157.0
PYH3_k127_6774186_8 Capsule assembly protein Wzi - - - 0.0000000000000000000000000000000000002599 160.0
PYH3_k127_6774186_9 NIL - - - 0.000000000000000000000000000000000003763 141.0
PYH3_k127_6856156_0 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 619.0
PYH3_k127_6856156_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005724 559.0
PYH3_k127_6856156_2 methylglyoxal synthase activity K01734 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0008150,GO:0008152,GO:0008929,GO:0009058,GO:0009438,GO:0009987,GO:0016829,GO:0016835,GO:0016838,GO:0019242,GO:0042180,GO:0042181,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0071704,GO:1901576 4.2.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000006045 246.0
PYH3_k127_6856156_3 PFAM Rhomboid family K07059 - - 0.0000000000000000000000000000000000000000000000000000000000000001422 228.0
PYH3_k127_6856156_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000006847 197.0
PYH3_k127_6856156_5 phosphinothricin N-acetyltransferase activity - - - 0.000000000000000000000000000000000003042 158.0
PYH3_k127_6856156_6 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000001137 105.0
PYH3_k127_6856156_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03116 - - 0.0000000000002072 74.0
PYH3_k127_6870692_0 response regulator - - - 9.88e-204 644.0
PYH3_k127_6870692_1 PFAM Polysulphide reductase, NrfD - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 569.0
PYH3_k127_6870692_10 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000008144 151.0
PYH3_k127_6870692_11 TIGRFAM diguanylate cyclase K02488 - 2.7.7.65 0.0000000000000000000000000000000001654 137.0
PYH3_k127_6870692_12 - - - - 0.000000000000000000000000000004911 125.0
PYH3_k127_6870692_13 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000003725 99.0
PYH3_k127_6870692_14 phosphorelay signal transduction system K03413,K07315,K13924 - 2.1.1.80,3.1.1.61,3.1.3.3 0.00000000003316 67.0
PYH3_k127_6870692_15 - - - - 0.0000007855 53.0
PYH3_k127_6870692_2 4Fe-4S dicluster domain - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 466.0
PYH3_k127_6870692_3 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 475.0
PYH3_k127_6870692_4 PFAM ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002137 376.0
PYH3_k127_6870692_5 Periplasmic binding protein K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 377.0
PYH3_k127_6870692_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 357.0
PYH3_k127_6870692_7 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001362 249.0
PYH3_k127_6870692_8 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000001188 191.0
PYH3_k127_6870692_9 Class III cytochrome C family - - - 0.000000000000000000000000000000000000000000000000006697 186.0
PYH3_k127_6936094_0 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174,K00186 - 1.2.7.11,1.2.7.3,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003976 446.0
PYH3_k127_6936094_1 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003102 371.0
PYH3_k127_6936094_2 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000000000000002144 219.0
PYH3_k127_6936094_3 PFAM Pyruvate ketoisovalerate oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000001119 197.0
PYH3_k127_6936094_4 Histidine kinase K03406,K13487 - - 0.0000000000000000000000000000000000000000000000000002418 193.0
PYH3_k127_6936094_5 PFAM Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000001528 82.0
PYH3_k127_6936094_6 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000001635 85.0
PYH3_k127_6955145_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0003674,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.354e-263 832.0
PYH3_k127_7036003_0 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000008704 211.0
PYH3_k127_7036003_1 ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000001211 188.0
PYH3_k127_7036003_2 B12 binding domain K01849 - 5.4.99.2 0.00000000000000000000000000000000000000000000001531 178.0
PYH3_k127_7036003_3 - - - - 0.00000000000000000000000000000000000000000000007332 173.0
PYH3_k127_7036003_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000005893 151.0
PYH3_k127_7036003_5 GTPase activity K07588 - - 0.00000000000000000000176 96.0
PYH3_k127_706869_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1566.0
PYH3_k127_706869_1 Multicopper oxidase K06324 - 1.16.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 568.0
PYH3_k127_706869_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004114 366.0
PYH3_k127_706869_3 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.00000000000000000000000000000000000000000008245 178.0
PYH3_k127_706869_4 NosL - - - 0.000000000000000000000002466 104.0
PYH3_k127_706869_5 Thioredoxin-like - - - 0.000000000000000000000003103 109.0
PYH3_k127_706869_6 PFAM Isoprenylcysteine carboxyl methyltransferase - - - 0.0000000000006346 75.0
PYH3_k127_7096078_0 PFAM Type II secretion system protein E K02454 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003443 624.0
PYH3_k127_7096078_1 Type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 508.0
PYH3_k127_7096078_10 Prokaryotic N-terminal methylation motif K02457 - - 0.0000007159 60.0
PYH3_k127_7096078_11 overlaps another CDS with the same product name K02458 - - 0.0006192 51.0
PYH3_k127_7096078_12 Belongs to the peptidase S8 family K13274,K20276 - - 0.0008714 46.0
PYH3_k127_7096078_2 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 306.0
PYH3_k127_7096078_3 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000247 194.0
PYH3_k127_7096078_4 Domain present in PSD-95, Dlg, and ZO-1/2. K02452 - - 0.000000000000000000000000000000000000000000004353 178.0
PYH3_k127_7096078_5 PFAM General secretion pathway protein K K02460 - - 0.0000000000000000000000000000001097 141.0
PYH3_k127_7096078_6 Involved in a type II secretion system (T2SS, formerly general secretion pathway, GSP) for the export of proteins - - - 0.00000000000009228 78.0
PYH3_k127_7096078_7 Fimbrial assembly family protein K02461 - - 0.0000000004215 72.0
PYH3_k127_7096078_8 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.00000005301 63.0
PYH3_k127_7096078_9 general secretion pathway protein K02459 GO:0002790,GO:0006810,GO:0008104,GO:0008150,GO:0009306,GO:0009987,GO:0015031,GO:0015628,GO:0015833,GO:0032940,GO:0033036,GO:0042886,GO:0045184,GO:0046903,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0098776 - 0.0000004619 61.0
PYH3_k127_7103577_0 TIGRFAM type IV pilus assembly protein PilM K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 354.0
PYH3_k127_7103577_1 type IV pilus secretin PilQ K02666 - - 0.000000000000000000000000000000000000000000000000000000000000002853 241.0
PYH3_k127_7103577_2 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000151 149.0
PYH3_k127_7103577_3 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000005033 106.0
PYH3_k127_7103577_4 PFAM helix-turn-helix domain protein - - - 0.0000000000000003099 80.0
PYH3_k127_7103577_5 Pilus assembly protein PilX - - - 0.000000000000001111 91.0
PYH3_k127_7103577_6 Pilus assembly protein, PilP K02665 - - 0.000000000000611 76.0
PYH3_k127_7103577_7 COG2931, RTX toxins and related Ca2 -binding proteins K20276 - - 0.00000002316 68.0
PYH3_k127_7218388_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1675.0
PYH3_k127_7218388_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1452.0
PYH3_k127_7328902_0 Alpha-tubulin suppressor and related RCC1 domain-containing - - - 5.739e-269 848.0
PYH3_k127_7328902_1 HELICc2 K03722 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 595.0
PYH3_k127_7328902_10 histidine kinase A domain protein - - - 0.0000000003647 70.0
PYH3_k127_7328902_2 ABC1 family K03688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 458.0
PYH3_k127_7328902_3 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007687 281.0
PYH3_k127_7328902_4 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000009317 231.0
PYH3_k127_7328902_5 Membrane transport protein K07088 - - 0.000000000000000000000000000000000000000000000000000000000000001043 229.0
PYH3_k127_7328902_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000001449 181.0
PYH3_k127_7328902_7 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000263 164.0
PYH3_k127_7328902_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000003519 143.0
PYH3_k127_7328902_9 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000003444 116.0
PYH3_k127_7337575_0 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 451.0
PYH3_k127_7337575_1 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 298.0
PYH3_k127_7337575_2 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000003056 95.0
PYH3_k127_7377133_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 6.038e-223 705.0
PYH3_k127_7377133_1 Uncharacterized conserved protein (DUF2075) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 389.0
PYH3_k127_7377133_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000003821 83.0
PYH3_k127_7377133_4 - - - - 0.00007729 48.0
PYH3_k127_7413532_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 1.366e-239 768.0
PYH3_k127_7413532_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000896 566.0
PYH3_k127_7413532_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000048 372.0
PYH3_k127_7413532_3 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004257 354.0
PYH3_k127_7413532_4 SurA N-terminal domain K03769 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000005224 197.0
PYH3_k127_7413532_5 4Fe-4S dicluster domain K00196 - - 0.00000000000000000000000000000000000000000000004257 174.0
PYH3_k127_7413532_6 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.00000000000000000000000000215 124.0
PYH3_k127_7413532_7 - - - - 0.0002962 43.0
PYH3_k127_7438153_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 2.736e-284 883.0
PYH3_k127_7438153_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000001559 79.0
PYH3_k127_7453364_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.021e-239 761.0
PYH3_k127_7453364_1 UvrD/REP helicase N-terminal domain K03656,K03657 GO:0000018,GO:0000166,GO:0000287,GO:0003674,GO:0003678,GO:0003824,GO:0004003,GO:0004386,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0006996,GO:0008026,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009411,GO:0009416,GO:0009628,GO:0009650,GO:0009892,GO:0009987,GO:0010605,GO:0016020,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0030312,GO:0030554,GO:0031323,GO:0031324,GO:0032392,GO:0032508,GO:0032552,GO:0032554,GO:0032558,GO:0032564,GO:0032991,GO:0033202,GO:0033554,GO:0034641,GO:0036094,GO:0040007,GO:0042623,GO:0043138,GO:0043140,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0045910,GO:0045934,GO:0046483,GO:0046872,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051053,GO:0051171,GO:0051172,GO:0051276,GO:0051716,GO:0060255,GO:0060542,GO:0060543,GO:0065007,GO:0070035,GO:0071103,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0090304,GO:0097159,GO:0097367,GO:0140097,GO:1901265,GO:1901360,GO:1901363,GO:1902494 3.6.4.12 7.609e-200 647.0
PYH3_k127_7453364_10 TPR repeat-containing protein - - - 0.000000000000000000000006507 114.0
PYH3_k127_7453364_11 translation initiation factor activity K03646 - - 0.000000000000002424 89.0
PYH3_k127_7453364_12 Kelch - - - 0.000000000000003428 87.0
PYH3_k127_7453364_13 Membrane - - - 0.00000000000002925 81.0
PYH3_k127_7453364_14 domain, Protein - - - 0.0000000002976 68.0
PYH3_k127_7453364_15 - - - - 0.00000008232 65.0
PYH3_k127_7453364_16 Tetratricopeptide repeat - - - 0.0000001923 64.0
PYH3_k127_7453364_17 Thioredoxin - - - 0.000001271 57.0
PYH3_k127_7453364_18 - - - - 0.000001995 50.0
PYH3_k127_7453364_19 Uncharacterized protein family, UPF0114 - - - 0.0008049 50.0
PYH3_k127_7453364_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 574.0
PYH3_k127_7453364_3 Nucleotidyl transferase K04042,K11528 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 423.0
PYH3_k127_7453364_4 PFAM 6-phosphogluconate dehydrogenase NAD-binding K00033 - 1.1.1.343,1.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009097 364.0
PYH3_k127_7453364_5 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 370.0
PYH3_k127_7453364_6 PFAM SPFH domain Band 7 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 333.0
PYH3_k127_7453364_7 AAA domain, putative AbiEii toxin, Type IV TA system K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 324.0
PYH3_k127_7453364_8 Psort location Extracellular, score - - - 0.0000000000000000000000000000000000000000000000000000000000000001188 231.0
PYH3_k127_7453364_9 TIGRFAM ABC-2 type transporter, NodJ K09694 - - 0.00000000000000000000000000000000000000000000000000000000000009734 229.0
PYH3_k127_7508129_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.474e-258 810.0
PYH3_k127_7508129_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 4.64e-207 652.0
PYH3_k127_7508129_10 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000239 126.0
PYH3_k127_7508129_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008012 443.0
PYH3_k127_7508129_3 Carboxyl transferase domain K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002516 380.0
PYH3_k127_7508129_4 transferase activity, transferring glycosyl groups K00720 - 2.4.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 313.0
PYH3_k127_7508129_5 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009336 296.0
PYH3_k127_7508129_6 Belongs to the ATCase OTCase family K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001804 279.0
PYH3_k127_7508129_7 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000001082 221.0
PYH3_k127_7508129_8 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000001259 212.0
PYH3_k127_7508129_9 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000328 216.0
PYH3_k127_7556331_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 326.0
PYH3_k127_7556331_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000003399 188.0
PYH3_k127_7556331_2 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000004599 174.0
PYH3_k127_7556331_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000006093 126.0
PYH3_k127_7556331_4 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000001343 87.0
PYH3_k127_7557805_0 Histidine kinase - - - 0.000000000000000000000000008058 127.0
PYH3_k127_7557805_1 - - - - 0.00000000004744 70.0
PYH3_k127_7557805_2 lyase activity - - - 0.000000002339 70.0
PYH3_k127_7611547_0 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.0 1092.0
PYH3_k127_7611547_1 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.332e-282 892.0
PYH3_k127_7611547_10 metal-dependent phosphohydrolase HD region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 491.0
PYH3_k127_7611547_11 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 GO:0003674,GO:0003824,GO:0004125,GO:0006139,GO:0006399,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016785,GO:0018130,GO:0019438,GO:0032774,GO:0034641,GO:0034654,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097056,GO:0140098,GO:0140101,GO:1901360,GO:1901362,GO:1901576 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001232 447.0
PYH3_k127_7611547_12 phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 427.0
PYH3_k127_7611547_13 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006049 398.0
PYH3_k127_7611547_14 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 381.0
PYH3_k127_7611547_15 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009049 385.0
PYH3_k127_7611547_16 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006768 365.0
PYH3_k127_7611547_17 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 365.0
PYH3_k127_7611547_18 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 327.0
PYH3_k127_7611547_19 Type I restriction enzyme R protein N terminus (HSDR_N) K07504 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 302.0
PYH3_k127_7611547_2 DNA polymerase A domain K02335 - 2.7.7.7 6.059e-274 871.0
PYH3_k127_7611547_20 PFAM EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 296.0
PYH3_k127_7611547_21 beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003613 276.0
PYH3_k127_7611547_22 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006814 265.0
PYH3_k127_7611547_23 Formate dehydrogenase N, transmembrane K00124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007295 261.0
PYH3_k127_7611547_24 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.00000000000000000000000000000000000000000000000000000000000000000000000001942 261.0
PYH3_k127_7611547_25 cAMP phosphodiesterases class-II K01120 - 3.1.4.17 0.0000000000000000000000000000000000000000000000000000000000000000000000003526 254.0
PYH3_k127_7611547_26 PFAM Molybdopterin oxidoreductase Fe4S4 region K00123 - 1.17.1.9 0.0000000000000000000000000000000000000000000000000000000000000000001876 235.0
PYH3_k127_7611547_27 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors - - - 0.000000000000000000000000000000000000000000000000000000000000000000398 239.0
PYH3_k127_7611547_28 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.00000000000000000000000000000000000000000000000000000000000000008472 245.0
PYH3_k127_7611547_29 NAD(P)H-binding K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000004623 211.0
PYH3_k127_7611547_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 2.429e-226 719.0
PYH3_k127_7611547_30 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000005039 218.0
PYH3_k127_7611547_31 regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000108 200.0
PYH3_k127_7611547_32 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000007638 195.0
PYH3_k127_7611547_33 CoA binding domain K01740,K06929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.5.1.49 0.000000000000000000000000000000000000000000000888 169.0
PYH3_k127_7611547_34 formate dehydrogenase K00127,K08350 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006082,GO:0006091,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009055,GO:0009061,GO:0009326,GO:0009987,GO:0015942,GO:0015944,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016903,GO:0016999,GO:0017144,GO:0019752,GO:0020037,GO:0022900,GO:0031224,GO:0031226,GO:0032787,GO:0032991,GO:0033554,GO:0036397,GO:0043436,GO:0044237,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045333,GO:0046906,GO:0048037,GO:0050896,GO:0051716,GO:0052738,GO:0055114,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.00000000000000000000000000000000000000000005776 167.0
PYH3_k127_7611547_35 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000009843 177.0
PYH3_k127_7611547_36 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000000002253 143.0
PYH3_k127_7611547_37 Necessary for formate dehydrogenase activity K02380 - - 0.000000000000000000000000004585 122.0
PYH3_k127_7611547_38 PFAM Cold-shock protein, DNA-binding K03704 - - 0.00000000000000000000000004885 109.0
PYH3_k127_7611547_39 DNA-binding transcription factor activity K03892 - - 0.00000000000000003888 94.0
PYH3_k127_7611547_4 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 3.439e-212 698.0
PYH3_k127_7611547_40 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000002358 88.0
PYH3_k127_7611547_41 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP - - - 0.000000000000002056 84.0
PYH3_k127_7611547_42 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000003879 78.0
PYH3_k127_7611547_43 Putative regulatory protein - - - 0.00000000000176 69.0
PYH3_k127_7611547_44 - - - - 0.00000001969 67.0
PYH3_k127_7611547_45 peptidyl-tyrosine sulfation - - - 0.00000002656 66.0
PYH3_k127_7611547_46 RNA-binding protein - - - 0.0000004006 56.0
PYH3_k127_7611547_47 Transcriptional regulator - - - 0.0001792 48.0
PYH3_k127_7611547_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 614.0
PYH3_k127_7611547_6 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 609.0
PYH3_k127_7611547_7 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002479 590.0
PYH3_k127_7611547_8 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002142 563.0
PYH3_k127_7611547_9 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 508.0
PYH3_k127_7624948_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 397.0
PYH3_k127_7624948_1 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000001173 158.0
PYH3_k127_7624948_2 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000001248 148.0
PYH3_k127_7624948_3 Ribosomal protein L22p/L17e K02890 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000004466 126.0
PYH3_k127_7624948_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000007308 107.0
PYH3_k127_7624948_5 Forms part of the polypeptide exit tunnel K02926 - - 0.0000000000005641 72.0
PYH3_k127_7656669_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 583.0
PYH3_k127_7688888_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 366.0
PYH3_k127_7688888_1 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 357.0
PYH3_k127_7688888_2 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006138 268.0
PYH3_k127_7688888_3 Nitroreductase family - - - 0.000000000000000000000000000000000000000000002366 170.0
PYH3_k127_7710954_0 Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA K12297 - 2.1.1.173,2.1.1.264 4.047e-249 789.0
PYH3_k127_7710954_1 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006508 482.0
PYH3_k127_7710954_2 PFAM YeeE YedE family (DUF395) K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004376 481.0
PYH3_k127_7710954_3 Cold-shock protein - - - 0.0000000000000000000000008736 104.0
PYH3_k127_7710954_4 - - - - 0.00000000000004984 74.0
PYH3_k127_7710954_5 Flavodoxin domain - - - 0.000001864 56.0
PYH3_k127_7730915_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 511.0
PYH3_k127_7730915_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 389.0
PYH3_k127_7730915_2 Periplasmic binding protein K07121 - - 0.0000000000000000000000000000000000000000000000000000003196 216.0
PYH3_k127_7730915_3 Bacitracin resistance protein BacA K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000001466 188.0
PYH3_k127_7730915_4 Ribosomal RNA adenine dimethylases K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000003461 175.0
PYH3_k127_7730915_5 TPR repeat-containing protein - - - 0.000000000000000000000001782 114.0
PYH3_k127_7730915_6 - - - - 0.000000000000000000000246 103.0
PYH3_k127_7732519_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003371 471.0
PYH3_k127_7732519_1 ATP phosphoribosyltransferase K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 398.0
PYH3_k127_7732519_2 Radical SAM superfamily K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000752 359.0
PYH3_k127_7732519_3 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000001187 248.0
PYH3_k127_7732519_4 SMART Elongator protein 3 MiaB NifB K07139 - - 0.0000000000000000000000000000000000000000000000000002424 198.0
PYH3_k127_7732519_5 PilZ domain - - - 0.0000000000000000000000000000000000002132 149.0
PYH3_k127_7732519_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000003105 81.0
PYH3_k127_7732519_7 - - - - 0.0000001573 61.0
PYH3_k127_7865629_0 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 5.067e-237 748.0
PYH3_k127_7865629_1 Dehydratase family K01687 - 4.2.1.9 2.855e-216 686.0
PYH3_k127_7865629_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000009464 179.0
PYH3_k127_7865629_11 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000004312 187.0
PYH3_k127_7865629_12 ROK family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000001344 165.0
PYH3_k127_7865629_14 FR47-like protein K03789 - 2.3.1.128 0.0000000000000000000000000000007314 133.0
PYH3_k127_7865629_15 - - - - 0.00000000000000000000000000002567 133.0
PYH3_k127_7865629_16 glycoprotease K14742 - - 0.00000000000000000000002573 114.0
PYH3_k127_7865629_17 - - - - 0.00000000000000000000005449 108.0
PYH3_k127_7865629_18 Protein of unknown function (DUF465) K09794 - - 0.0000001111 55.0
PYH3_k127_7865629_19 - - - - 0.0000001845 61.0
PYH3_k127_7865629_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 3.954e-204 647.0
PYH3_k127_7865629_20 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589,K13052 - - 0.0000001848 56.0
PYH3_k127_7865629_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 605.0
PYH3_k127_7865629_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005361 440.0
PYH3_k127_7865629_5 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K01835,K01840 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003241 426.0
PYH3_k127_7865629_6 Carbon-nitrogen hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000492 260.0
PYH3_k127_7865629_7 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000005049 240.0
PYH3_k127_7865629_8 TIGRFAM Acetolactate synthase, small subunit K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000001933 219.0
PYH3_k127_7865629_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000005268 213.0
PYH3_k127_7905544_0 COG1032 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000169 217.0
PYH3_k127_7905544_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000004183 179.0
PYH3_k127_7905544_2 nucleotide phosphatase activity, acting on free nucleotides K00943,K02013,K02017,K03574,K03752,K06928 - 2.7.4.9,2.7.7.77,3.6.1.15,3.6.1.55,3.6.3.29,3.6.3.34 0.0000000000000000000000000000005892 128.0
PYH3_k127_7905544_3 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000004501 117.0
PYH3_k127_7905544_4 Transmembrane and - - - 0.00000000000000108 87.0
PYH3_k127_7933741_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 464.0
PYH3_k127_7933741_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000001146 118.0
PYH3_k127_8003159_0 Bacterial capsule synthesis protein PGA_cap K07282 - - 0.000000000000000000000000000000000000000000000000000000000000000001517 240.0
PYH3_k127_8003159_1 - - - - 0.000000000000000000000000000000000000000000000000001037 202.0
PYH3_k127_8003159_2 - - - - 0.0000000000000000000000000000000000000000001497 163.0
PYH3_k127_8003159_3 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000001949 141.0
PYH3_k127_8003159_4 PFAM Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000006838 117.0
PYH3_k127_8037839_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 6.362e-300 942.0
PYH3_k127_8037839_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 6.273e-268 839.0
PYH3_k127_8037839_10 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000003886 123.0
PYH3_k127_8037839_11 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000003326 109.0
PYH3_k127_8037839_12 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.170 0.0000000000000000000000113 109.0
PYH3_k127_8037839_13 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000001097 85.0
PYH3_k127_8037839_14 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000005781 74.0
PYH3_k127_8037839_15 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.0000000001294 74.0
PYH3_k127_8037839_2 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 1.759e-215 687.0
PYH3_k127_8037839_3 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 468.0
PYH3_k127_8037839_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 348.0
PYH3_k127_8037839_5 PFAM Cobyrinic acid ac-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003987 324.0
PYH3_k127_8037839_6 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 298.0
PYH3_k127_8037839_7 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000004036 271.0
PYH3_k127_8037839_8 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000001192 239.0
PYH3_k127_8037839_9 it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP K03629 GO:0000731,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009295,GO:0009987,GO:0018130,GO:0019438,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043590,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:1901360,GO:1901362,GO:1901576 - 0.00000000000000000000000000000000000000000000000000006939 200.0
PYH3_k127_8129996_0 phosphatidate phosphatase activity K03975,K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 402.0
PYH3_k127_8129996_1 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000003686 207.0
PYH3_k127_8129996_10 anaerobic respiration - - - 0.000005504 54.0
PYH3_k127_8129996_11 Resolvase, N terminal domain - - - 0.00006785 48.0
PYH3_k127_8129996_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000002473 144.0
PYH3_k127_8129996_3 GIY-YIG catalytic domain - - - 0.00000000000000000000000000003173 121.0
PYH3_k127_8129996_4 Protein of unknown function (DUF2628) - - - 0.00000000000000000000000000046 121.0
PYH3_k127_8129996_5 Protein of unknown function (DUF2628) - - - 0.0000000000000000000009136 102.0
PYH3_k127_8129996_8 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000001118 78.0
PYH3_k127_8129996_9 GIY-YIG catalytic domain K07461 - - 0.00000000106 62.0
PYH3_k127_8170669_0 Threonine synthase K01733 - 4.2.3.1 3.145e-199 634.0
PYH3_k127_8170669_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0008684 44.0
PYH3_k127_8231070_0 Belongs to the RtcB family K14415 GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008747 579.0
PYH3_k127_8231070_1 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0010467,GO:0016485,GO:0016540,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0051604,GO:0071704,GO:1901564 4.1.1.11 0.00000000000000000000000000000000006673 136.0
PYH3_k127_8231070_2 Archease protein family (MTH1598/TM1083) - - - 0.000000000000000000035 95.0
PYH3_k127_8237258_0 Penicillin-binding protein 1A K05366,K21464 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 548.0
PYH3_k127_8237258_1 TIGRFAM cytochrome C family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 383.0
PYH3_k127_8237258_2 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 324.0
PYH3_k127_8237258_3 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003095 250.0
PYH3_k127_8237258_4 HD domain K07814 - - 0.00000000000000000000000000000000000002242 166.0
PYH3_k127_8237258_5 Flavin containing amine oxidoreductase K09835 - 5.2.1.13 0.0000000000000000000000000000000007966 148.0
PYH3_k127_8237258_6 - - - - 0.00000000000000000000000000000006092 128.0
PYH3_k127_8237258_7 amine dehydrogenase activity K21449 - - 0.0000000000000000000000000002018 121.0
PYH3_k127_8237258_8 denitrification pathway - - - 0.000000000000007028 89.0
PYH3_k127_8238964_0 TIGRFAM penicillin-binding protein, 1A family K05366 - 2.4.1.129,3.4.16.4 7.23e-210 680.0
PYH3_k127_8238964_1 IMP dehydrogenase / GMP reductase domain K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001618 517.0
PYH3_k127_8238964_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000001663 234.0
PYH3_k127_8238964_11 Probable RNA and SrmB- binding site of polymerase A K00970 - 2.7.7.19 0.0000000000000000000000000000000000000000000000000000000002166 220.0
PYH3_k127_8238964_12 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000002146 203.0
PYH3_k127_8238964_13 Ami_3 K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000002153 189.0
PYH3_k127_8238964_14 Belongs to the GSP D family K02280 - - 0.00000000000000000000000000000000000000000001449 177.0
PYH3_k127_8238964_15 Protein of unknown function (DUF3187) - - - 0.000000000000000000000000000000000000000006012 168.0
PYH3_k127_8238964_16 Ribosomal protein L11 methyltransferase K02687 - - 0.00000000000000000000000000000000000000001849 168.0
PYH3_k127_8238964_17 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.000000000000000000000000000000000000001325 165.0
PYH3_k127_8238964_18 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000002463 131.0
PYH3_k127_8238964_19 - - - - 0.00000000000000000000006186 115.0
PYH3_k127_8238964_2 Secretion system protein K02283 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002356 446.0
PYH3_k127_8238964_20 Sporulation and spore germination - - - 0.0000000000000000000001169 108.0
PYH3_k127_8238964_21 RDD family - - - 0.00000000000000003465 89.0
PYH3_k127_8238964_22 Transmembrane and - - - 0.00000000000001056 86.0
PYH3_k127_8238964_23 Flp pilus assembly protein RcpC/CpaB K02279 - - 0.0000000000009393 79.0
PYH3_k127_8238964_24 Type II secretion system K12510 - - 0.0000000000009794 78.0
PYH3_k127_8238964_27 - - - - 0.000001036 51.0
PYH3_k127_8238964_28 Belongs to the pirin family K06911 - - 0.00000182 56.0
PYH3_k127_8238964_29 Uncharacterized ACR, COG1430 K09005 - - 0.0000263 52.0
PYH3_k127_8238964_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K07138 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 400.0
PYH3_k127_8238964_31 Type II secretion system K12511 - - 0.0001225 55.0
PYH3_k127_8238964_32 - - - - 0.0006129 51.0
PYH3_k127_8238964_4 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 386.0
PYH3_k127_8238964_5 anaerobic respiration - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001761 347.0
PYH3_k127_8238964_6 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989,K02428 - 2.7.7.56,3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 288.0
PYH3_k127_8238964_7 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007452 282.0
PYH3_k127_8238964_8 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001838 268.0
PYH3_k127_8238964_9 endonuclease III K07457 - - 0.00000000000000000000000000000000000000000000000000000000000002659 229.0
PYH3_k127_8252433_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.408e-199 634.0
PYH3_k127_8252433_1 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007675 358.0
PYH3_k127_8252433_2 Phosphoribosylformylglycinamidine (FGAM) synthase K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000005981 246.0
PYH3_k127_8278682_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 1.143e-300 949.0
PYH3_k127_8278682_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 527.0
PYH3_k127_8278682_10 TPR repeat - - - 0.00000000000000000000000000000000000000000000000008744 195.0
PYH3_k127_8278682_11 regulator - - - 0.0000000000000000000000000000000000000000000000001887 200.0
PYH3_k127_8278682_12 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000000000000003972 184.0
PYH3_k127_8278682_13 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000004145 198.0
PYH3_k127_8278682_14 Lysin motif - - - 0.0000000000000000000000000000000000004966 154.0
PYH3_k127_8278682_15 Ferric uptake regulator family K09825 - - 0.0000000000000000000000000000000000007177 144.0
PYH3_k127_8278682_16 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 - - 0.000000000000000000003159 110.0
PYH3_k127_8278682_17 Preprotein translocase SecG subunit K03075 - - 0.0000000000000000001539 92.0
PYH3_k127_8278682_18 Hsp20/alpha crystallin family K13993 - - 0.0000000000000001633 87.0
PYH3_k127_8278682_19 Two component signalling adaptor domain K03408 - - 0.00000000009339 69.0
PYH3_k127_8278682_2 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004664 473.0
PYH3_k127_8278682_20 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0006768 50.0
PYH3_k127_8278682_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 441.0
PYH3_k127_8278682_4 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 332.0
PYH3_k127_8278682_5 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 301.0
PYH3_k127_8278682_6 transmembrane signaling receptor activity K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006521 276.0
PYH3_k127_8278682_7 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor domain - - - 0.000000000000000000000000000000000000000000000000002409 203.0
PYH3_k127_8278682_8 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K13924 - 2.1.1.80,3.1.1.61 0.00000000000000000000000000000000000000000000000002335 190.0
PYH3_k127_8278682_9 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000004077 205.0
PYH3_k127_8316733_0 PFAM Radical SAM domain protein K22227 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 521.0
PYH3_k127_8316733_1 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 392.0
PYH3_k127_8316733_10 Forms part of a two-component regulatory system AfsQ1 AfsQ2 involved in secondary metabolism - - - 0.0000008848 60.0
PYH3_k127_8316733_11 LppC putative lipoprotein - - - 0.0000418 49.0
PYH3_k127_8316733_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 342.0
PYH3_k127_8316733_3 Ferrochelatase K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 291.0
PYH3_k127_8316733_4 SMART CBS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008659 267.0
PYH3_k127_8316733_5 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000009127 240.0
PYH3_k127_8316733_6 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000004078 172.0
PYH3_k127_8316733_7 tRNA (adenine(22)-N(1))-methyltransferase K06967 - 2.1.1.217 0.000000000000000000000000000002377 128.0
PYH3_k127_8316733_8 - - - - 0.00000000000000000000004906 102.0
PYH3_k127_8316733_9 C4-type zinc ribbon domain K07164 - - 0.000000002076 58.0
PYH3_k127_83280_0 flavodoxin nitric oxide synthase K22405 - 1.6.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 432.0
PYH3_k127_83280_1 glutamine amidotransferase K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000006236 183.0
PYH3_k127_83280_2 Peptidase family M23 - - - 0.000000000000000000000000000000000000000003237 167.0
PYH3_k127_83280_3 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.0000000000000000000009386 94.0
PYH3_k127_83280_4 PFAM nitrogen-fixing NifU domain protein - - - 0.0000000000000000004729 98.0
PYH3_k127_83280_5 Zn peptidase - - - 0.000000000000001269 82.0
PYH3_k127_83280_6 Belongs to the N(4) N(6)-methyltransferase family K00571,K13581 - 2.1.1.72 0.0000184 48.0
PYH3_k127_8346506_0 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000000000000000000135 199.0
PYH3_k127_8346506_1 RNA polymerase sigma factor K03088 - - 0.000000000000000000000000000002094 127.0
PYH3_k127_8346506_2 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000002696 120.0
PYH3_k127_8346506_3 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0001993 51.0
PYH3_k127_8353760_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 6.589e-249 781.0
PYH3_k127_8353760_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 4.099e-236 738.0
PYH3_k127_8353760_10 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045263,GO:0045264,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000419 68.0
PYH3_k127_8353760_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000002829 63.0
PYH3_k127_8353760_12 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0006014 51.0
PYH3_k127_8353760_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.746e-231 723.0
PYH3_k127_8353760_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 1.121e-217 704.0
PYH3_k127_8353760_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0030312,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0040007,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0044769,GO:0045259,GO:0045260,GO:0045261,GO:0045262,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0071944,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0098797,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002001 306.0
PYH3_k127_8353760_5 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002742 257.0
PYH3_k127_8353760_6 ATP hydrolysis coupled proton transport K02110,K02124 GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0042623,GO:0042625,GO:0042626,GO:0042802,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000000000000002179 143.0
PYH3_k127_8353760_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000007607 135.0
PYH3_k127_8353760_8 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000004141 128.0
PYH3_k127_8353760_9 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.0000000000000000000002672 107.0
PYH3_k127_8377037_0 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 434.0
PYH3_k127_8377037_1 GDP-mannose 4,6 dehydratase K15856 - 1.1.1.281 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005353 360.0
PYH3_k127_8377037_10 NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000001486 231.0
PYH3_k127_8377037_11 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000146 215.0
PYH3_k127_8377037_12 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000000000000000003001 226.0
PYH3_k127_8377037_13 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000002167 193.0
PYH3_k127_8377037_14 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000001422 203.0
PYH3_k127_8377037_15 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000006681 195.0
PYH3_k127_8377037_16 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966,K03273,K15669 - 2.7.7.13,2.7.7.71,3.1.3.82,3.1.3.83 0.00000000000000000000000000000000000000000000001074 181.0
PYH3_k127_8377037_17 Methyltransferase domain - - - 0.000000000000000000000000000000001561 139.0
PYH3_k127_8377037_18 dTDP-4-dehydrorhamnose 3,5-epimerase K01790 - 5.1.3.13 0.0000000000000000000000000000005247 128.0
PYH3_k127_8377037_19 Polysaccharide biosynthesis C-terminal domain K03328 - - 0.000000000000000000000000000001482 139.0
PYH3_k127_8377037_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008191 356.0
PYH3_k127_8377037_20 Glycosyl transferases group 1 K16150 GO:0000271,GO:0003674,GO:0003824,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0009058,GO:0009059,GO:0009103,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0040007,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.4.1.11 0.00000000000000000002261 104.0
PYH3_k127_8377037_21 methyltransferase K16215 - 2.1.1.243 0.000000000000000004973 93.0
PYH3_k127_8377037_22 Methyltransferase - - - 0.00000000000000001829 91.0
PYH3_k127_8377037_23 cell redox homeostasis K03671 - - 0.00000000000009402 77.0
PYH3_k127_8377037_24 - - - - 0.000001918 60.0
PYH3_k127_8377037_25 SurA N-terminal domain K01802,K03770 - 5.2.1.8 0.00006288 56.0
PYH3_k127_8377037_26 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.0001635 54.0
PYH3_k127_8377037_3 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005283 309.0
PYH3_k127_8377037_4 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002778 307.0
PYH3_k127_8377037_5 dTDP-4-dehydrorhamnose reductase activity K00067,K01790,K19997 - 1.1.1.133,5.1.3.13,5.1.3.26 0.00000000000000000000000000000000000000000000000000000000000000000000002368 269.0
PYH3_k127_8377037_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005004 252.0
PYH3_k127_8377037_7 Dehydrogenase E1 component K00161 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000001811 247.0
PYH3_k127_8377037_8 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.00000000000000000000000000000000000000000000000000000000000000002741 229.0
PYH3_k127_8377037_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000001324 230.0
PYH3_k127_8405673_0 UDP-N-acetylmuramate-L-alanine ligase activity K01924 - 6.3.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006185 544.0
PYH3_k127_8405673_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 538.0
PYH3_k127_8405673_10 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001822 264.0
PYH3_k127_8405673_11 Cell cycle protein K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003086 259.0
PYH3_k127_8405673_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000003545 256.0
PYH3_k127_8405673_13 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000004601 213.0
PYH3_k127_8405673_14 Belongs to the MraZ family K03925 GO:0000976,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0043254,GO:0043565,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000000000000000000000000000234 151.0
PYH3_k127_8405673_15 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000004668 140.0
PYH3_k127_8405673_16 Essential cell division protein K03589 - - 0.00000000002394 75.0
PYH3_k127_8405673_17 anaphase-promoting complex binding - - - 0.00000363 55.0
PYH3_k127_8405673_2 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 447.0
PYH3_k127_8405673_3 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 421.0
PYH3_k127_8405673_4 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 413.0
PYH3_k127_8405673_5 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007848 362.0
PYH3_k127_8405673_6 Predicted permease - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002848 322.0
PYH3_k127_8405673_7 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009737 316.0
PYH3_k127_8405673_8 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 295.0
PYH3_k127_8405673_9 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000009672 292.0
PYH3_k127_8465543_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009132 400.0
PYH3_k127_8465543_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.0005693 43.0
PYH3_k127_8591663_0 General secretory system II, protein E domain protein K02652 - - 3.032e-209 665.0
PYH3_k127_8591663_1 PFAM aminotransferase class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 385.0
PYH3_k127_8591663_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000003048 217.0
PYH3_k127_8591663_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.0000000000000000000000000000000000000000000000000448 194.0
PYH3_k127_8591663_4 radical SAM domain protein K06137,K06138 - 1.3.3.11 0.0000000000000283 79.0
PYH3_k127_8591663_5 Protein of unknown function (DUF3343) - - - 0.0002242 50.0
PYH3_k127_8634615_0 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 350.0
PYH3_k127_8634615_1 Belongs to the WrbA family K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008977 288.0
PYH3_k127_8634615_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000001825 228.0
PYH3_k127_8634615_3 Leucine carboxyl methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000004457 232.0
PYH3_k127_8634615_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K03406 - - 0.0000000000000000000000000000000000000000000000000000000001639 221.0
PYH3_k127_8634615_5 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000004325 183.0
PYH3_k127_8634615_6 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000007799 153.0
PYH3_k127_8634615_7 PFAM Cold-shock protein, DNA-binding K03704 - - 0.0000000000000000000000001621 109.0
PYH3_k127_8634615_8 ABC-type uncharacterized transport system - - - 0.00005188 48.0
PYH3_k127_8653197_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 2.241e-207 661.0
PYH3_k127_8653197_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002823 562.0
PYH3_k127_8653197_10 tRNA (Guanine-1)-methyltransferase K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 289.0
PYH3_k127_8653197_11 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003174 276.0
PYH3_k127_8653197_12 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001751 278.0
PYH3_k127_8653197_13 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000004322 231.0
PYH3_k127_8653197_14 Ribonuclease HII K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000751 204.0
PYH3_k127_8653197_15 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K07651 - 2.7.13.3 0.0000000000000000000000000000000000000000001408 184.0
PYH3_k127_8653197_16 Beta-lactamase K17836 - 3.5.2.6 0.000000000000000000000000000000000000004116 158.0
PYH3_k127_8653197_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000001386 158.0
PYH3_k127_8653197_18 large ribosomal subunit rRNA binding K02884 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070180,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001797 146.0
PYH3_k127_8653197_19 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000001215 142.0
PYH3_k127_8653197_2 surface antigen variable number repeat protein K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 531.0
PYH3_k127_8653197_20 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000005097 119.0
PYH3_k127_8653197_21 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000001354 126.0
PYH3_k127_8653197_22 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000000000000000000000001161 117.0
PYH3_k127_8653197_23 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000005272 110.0
PYH3_k127_8653197_24 PFAM FecR protein - - - 0.000000000000000000000001096 119.0
PYH3_k127_8653197_25 Belongs to the precorrin methyltransferase family K02302,K02303,K13542 - 1.3.1.76,2.1.1.107,4.2.1.75,4.99.1.4 0.000000000000000000001334 108.0
PYH3_k127_8653197_26 PFAM H transporting two-sector ATPase C subunit K02124 - - 0.0000000000000000006171 88.0
PYH3_k127_8653197_27 PFAM GGDEF domain containing protein - - - 0.00000000000006155 87.0
PYH3_k127_8653197_28 NhaP-type Na H and K H - - - 0.00000000001275 77.0
PYH3_k127_8653197_29 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000001945 74.0
PYH3_k127_8653197_3 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 458.0
PYH3_k127_8653197_30 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000001112 70.0
PYH3_k127_8653197_31 Part of a membrane complex involved in electron transport K03617 - - 0.000000007211 60.0
PYH3_k127_8653197_32 - - - - 0.0000405 53.0
PYH3_k127_8653197_33 sequence-specific DNA binding K15539 - - 0.00004662 53.0
PYH3_k127_8653197_34 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000551 49.0
PYH3_k127_8653197_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007123 449.0
PYH3_k127_8653197_5 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 449.0
PYH3_k127_8653197_6 Peptidase U62 modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003593 448.0
PYH3_k127_8653197_7 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 GO:0003674,GO:0003824,GO:0004418,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016740,GO:0016765,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 361.0
PYH3_k127_8653197_8 PFAM V-type ATPase 116 kDa K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 328.0
PYH3_k127_8653197_9 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 304.0
PYH3_k127_8697710_0 COG0058 Glucan phosphorylase - - - 7.112e-242 760.0
PYH3_k127_8697710_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 364.0
PYH3_k127_8697710_10 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000002954 117.0
PYH3_k127_8697710_11 AsmA family K07289,K07290 - - 0.0000000000000022 89.0
PYH3_k127_8697710_12 - - - - 0.000000001244 72.0
PYH3_k127_8697710_13 oxidoreductase activity - - - 0.00000171 61.0
PYH3_k127_8697710_2 Associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 341.0
PYH3_k127_8697710_3 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001551 275.0
PYH3_k127_8697710_4 tRNA synthetases class II (D, K and N) K04568 - - 0.0000000000000000000000000000000000000000000000000000000000000246 228.0
PYH3_k127_8697710_5 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000007522 211.0
PYH3_k127_8697710_6 Contains one ATP-binding region, ATPase-like domain (IPR003594) - - - 0.0000000000000000000000000000000000000000000000000000001056 219.0
PYH3_k127_8697710_7 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000000000000000000000000006215 169.0
PYH3_k127_8697710_8 Putative glutamine amidotransferase K07114 - - 0.000000000000000000000000000008609 138.0
PYH3_k127_8697710_9 GYD domain - - - 0.0000000000000000000000008819 118.0
PYH3_k127_8698036_0 SIS domain K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 329.0
PYH3_k127_8698036_1 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008781,GO:0009058,GO:0009059,GO:0009103,GO:0009987,GO:0016051,GO:0016311,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016791,GO:0019143,GO:0033692,GO:0034637,GO:0034645,GO:0042578,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0070567,GO:0071704,GO:1901135,GO:1901137,GO:1901576,GO:1903509 3.1.3.45 0.00000000000000000000000000000000000000002333 169.0
PYH3_k127_8698036_2 Methyltransferase domain - - - 0.00000000000000000002356 100.0
PYH3_k127_8698036_3 Lipopolysaccharide-assembly, LptC-related - - - 0.000001036 57.0
PYH3_k127_8700908_0 Belongs to the bacterial solute-binding protein 9 family K09815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004557 250.0
PYH3_k127_8700908_1 ATPases associated with a variety of cellular activities K09817 - - 0.000000000000000000000000000000000000000000000000000000000001011 216.0
PYH3_k127_8725371_0 oligosaccharyl transferase activity K07151 - 2.4.99.18 0.00000000000000000000000000001468 135.0
PYH3_k127_8725371_1 membrane protein, required for N-linked glycosylation K07151 GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016740,GO:0016757,GO:0045229,GO:0045232,GO:0071840 2.4.99.18 0.00000000002855 77.0
PYH3_k127_8727260_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.011e-198 629.0
PYH3_k127_8727260_1 Belongs to the EPSP synthase family. MurA subfamily K00790 - 2.5.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 488.0
PYH3_k127_8727260_10 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000084 258.0
PYH3_k127_8727260_11 imidazoleglycerol-phosphate dehydratase activity K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000103 245.0
PYH3_k127_8727260_12 Phosphoribosyl-AMP cyclohydrolase K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000000000000001553 240.0
PYH3_k127_8727260_13 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000006051 236.0
PYH3_k127_8727260_14 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.00000000000000000000000000000000000000000000000000000000000002838 232.0
PYH3_k127_8727260_15 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000009519 239.0
PYH3_k127_8727260_16 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000003535 216.0
PYH3_k127_8727260_17 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0004140,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032552,GO:0032553,GO:0032554,GO:0032557,GO:0032558,GO:0032564,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.24 0.00000000000000000000000000000000000000003725 160.0
PYH3_k127_8727260_18 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000003716 143.0
PYH3_k127_8727260_19 Yqey-like protein K09117 - - 0.000000000000000000000000000000000003613 142.0
PYH3_k127_8727260_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 461.0
PYH3_k127_8727260_20 PFAM BioY K03523 - - 0.00000000000000000000000000000006543 131.0
PYH3_k127_8727260_21 Binds the 23S rRNA K02909 - - 0.0000000000000000000000005365 105.0
PYH3_k127_8727260_22 diguanylate cyclase - - - 0.0000000000000000003481 100.0
PYH3_k127_8727260_23 Ribosomal protein S21 K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000001188 88.0
PYH3_k127_8727260_24 PIN domain - - - 0.000000000000003545 85.0
PYH3_k127_8727260_25 - K21495 - - 0.00000009573 56.0
PYH3_k127_8727260_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006166 439.0
PYH3_k127_8727260_4 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 440.0
PYH3_k127_8727260_5 alpha/beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 400.0
PYH3_k127_8727260_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 392.0
PYH3_k127_8727260_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 362.0
PYH3_k127_8727260_8 Protein of unknown function (DUF1385) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 322.0
PYH3_k127_8727260_9 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005508 281.0
PYH3_k127_8742765_0 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000001878 201.0
PYH3_k127_8742765_1 spermidine putrescine K02054 - - 0.0000000000000000000000000000000000000001266 158.0
PYH3_k127_8745854_0 lysine 2,3-aminomutase activity K01843,K19810 - 5.4.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 561.0
PYH3_k127_8745854_1 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 483.0
PYH3_k127_8745854_2 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006683 364.0
PYH3_k127_8745854_3 dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 327.0
PYH3_k127_8745854_4 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 302.0
PYH3_k127_8745854_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001634 252.0
PYH3_k127_8745854_6 acetyltransferase K18815 - 2.3.1.82 0.0000000000000000000000000000000000000000000006336 171.0
PYH3_k127_8745854_7 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000002424 91.0
PYH3_k127_8745854_8 helix_turn_helix multiple antibiotic resistance protein - - - 0.000003126 53.0
PYH3_k127_8745854_9 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00003771 48.0
PYH3_k127_8749504_0 Elongation factor Tu domain 2 K02355 - - 5.383e-222 707.0
PYH3_k127_8755612_0 Uncharacterized protein family, UPF0114 - - - 0.00000000000000000000000000000000000000000000000007234 195.0
PYH3_k127_8755612_1 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000004662 175.0
PYH3_k127_8755612_2 - - - - 0.0000000000000000000000000000000000000000001052 177.0
PYH3_k127_8755612_3 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000001157 145.0
PYH3_k127_8755612_4 Protein of unknown function (DUF1622) - - - 0.00000000000000001139 87.0
PYH3_k127_8755612_5 - - - - 0.00000004833 63.0
PYH3_k127_8782479_0 DivIVA protein K04074 - - 0.0000000000000000000000000000000001323 139.0
PYH3_k127_8782479_1 Belongs to the UPF0235 family K09131 - - 0.0000000000000001502 85.0
PYH3_k127_8782479_2 YGGT family K02221 - - 0.00000000000001871 77.0
PYH3_k127_8782479_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000123 68.0
PYH3_k127_8782479_4 Peptidase MA superfamily - - - 0.000000001767 70.0
PYH3_k127_8782479_5 PEGA domain - - - 0.00002038 57.0
PYH3_k127_8888432_0 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 297.0
PYH3_k127_8888432_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 293.0
PYH3_k127_8888432_2 In Spt5p, this domain may confer affinity for Spt4p. It possesses a RNP-like fold. K02601 - - 0.0000000000000000000000000000000000000000000000000000000000000000006109 233.0
PYH3_k127_8888432_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000006232 224.0
PYH3_k127_8888432_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000000000007078 169.0
PYH3_k127_8888432_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006417,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0015934,GO:0017148,GO:0019222,GO:0019538,GO:0022625,GO:0022626,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032268,GO:0032269,GO:0032991,GO:0034248,GO:0034249,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0044877,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051246,GO:0051248,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1990904,GO:2000112,GO:2000113 - 0.00000000000000000000000000000000000000000721 160.0
PYH3_k127_8888432_6 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000001778 88.0
PYH3_k127_8888432_7 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000006082 74.0
PYH3_k127_8888432_8 SecE/Sec61-gamma subunits of protein translocation complex K03073 - - 0.00000000008752 65.0
PYH3_k127_8924273_0 PFAM filamentation induced by cAMP protein Fic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009344 438.0
PYH3_k127_8924273_1 PIN domain - - - 0.000000000000000000000000000001146 129.0
PYH3_k127_8924273_2 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.0000000000000000000000007282 109.0
PYH3_k127_8924273_3 positive regulation of growth - - - 0.0000000000000000007119 88.0
PYH3_k127_8924273_4 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000711 75.0
PYH3_k127_8981714_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004251 576.0
PYH3_k127_8981714_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000206 506.0
PYH3_k127_8981714_10 Uncharacterised conserved protein (DUF2156) K01163 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 294.0
PYH3_k127_8981714_11 SNARE associated Golgi protein K19302 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000001155 274.0
PYH3_k127_8981714_12 regulator, PATAN and FRGAF domain-containing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004892 274.0
PYH3_k127_8981714_13 Protein of unknown function (DUF554) K07150 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001164 255.0
PYH3_k127_8981714_14 TIGRFAM MazG family protein K02499 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008636 254.0
PYH3_k127_8981714_15 PFAM CBS domain containing protein K06189 - - 0.000000000000000000000000000000000000000000000000000000000000000001995 237.0
PYH3_k127_8981714_16 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000001056 235.0
PYH3_k127_8981714_17 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000002355 217.0
PYH3_k127_8981714_18 Domain of unknown function (DUF4388) - - - 0.0000000000000000000000000000000000000000000000000000000000002565 240.0
PYH3_k127_8981714_19 MgtC family K07507 - - 0.0000000000000000000000000000000000000000000000000000000000004342 218.0
PYH3_k127_8981714_2 Signal transducing histidine kinase homodimeric K03407 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 509.0
PYH3_k127_8981714_20 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000002127 209.0
PYH3_k127_8981714_21 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000003223 191.0
PYH3_k127_8981714_22 HEAT repeat - - - 0.000000000000000000000000000000000000000000000000433 198.0
PYH3_k127_8981714_23 LemA family K03744 - - 0.000000000000000000000000000000000000000000000002644 179.0
PYH3_k127_8981714_24 Prokaryotic diacylglycerol kinase K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000007331 184.0
PYH3_k127_8981714_25 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000001078 189.0
PYH3_k127_8981714_26 PFAM CheW domain protein K03408 - - 0.00000000000000000000000000000000000000005231 166.0
PYH3_k127_8981714_27 PFAM response regulator receiver K03413 - - 0.000000000000000000000000000000000000003235 150.0
PYH3_k127_8981714_28 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000005598 139.0
PYH3_k127_8981714_29 PFAM Membrane protein of K08972 - - 0.00000000000000000000000000000002542 130.0
PYH3_k127_8981714_3 7TM-HD extracellular K07037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 469.0
PYH3_k127_8981714_30 E3 Ubiquitin ligase - - - 0.00000000000000000000000000000021 137.0
PYH3_k127_8981714_31 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000437 127.0
PYH3_k127_8981714_32 Redoxin - - - 0.0000000000000000000000000000339 119.0
PYH3_k127_8981714_33 zinc-ribbon domain - - - 0.0000000000000000000000000001592 126.0
PYH3_k127_8981714_34 Domain of unknown function (DUF305) - - - 0.000000000000000000001336 99.0
PYH3_k127_8981714_35 Thioredoxin - - - 0.00000000000000000002377 100.0
PYH3_k127_8981714_36 Uncharacterized protein family UPF0054 - - - 0.00000000000000000009967 95.0
PYH3_k127_8981714_37 Domain of unknown function (DUF1844) - - - 0.0000000000000001533 84.0
PYH3_k127_8981714_38 peptidyl-tyrosine sulfation - - - 0.00000000002708 77.0
PYH3_k127_8981714_39 Cytosol aminopeptidase family, N-terminal domain - - - 0.000000007445 66.0
PYH3_k127_8981714_4 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 400.0
PYH3_k127_8981714_40 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000005734 63.0
PYH3_k127_8981714_5 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005009 389.0
PYH3_k127_8981714_6 PhoH-like protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 353.0
PYH3_k127_8981714_7 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 336.0
PYH3_k127_8981714_8 Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP K00575 - 2.1.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 316.0
PYH3_k127_8981714_9 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001844 323.0
PYH3_k127_9004889_0 Carboxyl transferase domain K01966,K17489 - 2.1.3.1,2.1.3.15,6.4.1.3 1.086e-245 768.0
PYH3_k127_9004889_1 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 4.073e-236 741.0
PYH3_k127_9004889_2 Biotin carboxylase C-terminal domain K01961,K01965 - 6.3.4.14,6.4.1.2,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002428 547.0
PYH3_k127_9004889_3 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 355.0
PYH3_k127_9004889_4 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000001481 199.0
PYH3_k127_9004889_5 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.0000000000000000000000000000000000007421 145.0
PYH3_k127_9004889_6 lysyltransferase activity - - - 0.000000000000000000000000001077 125.0
PYH3_k127_9004889_7 Biotin-requiring enzyme - - - 0.000000000000000000000000004215 117.0
PYH3_k127_9004889_8 Membrane-associated phospholipid phosphatase K19302 - 3.6.1.27 0.000000000000002854 87.0
PYH3_k127_9052081_0 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 426.0
PYH3_k127_9052081_1 Calcineurin-like phosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004349 289.0
PYH3_k127_9052081_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000005007 211.0
PYH3_k127_9052081_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.00000000000000000000000000000000000000000004662 166.0
PYH3_k127_9052081_4 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000000006566 171.0
PYH3_k127_9157911_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 328.0
PYH3_k127_9157911_1 nitric oxide dioxygenase activity - - - 0.00000000000000000000000002542 123.0
PYH3_k127_9157911_2 Nucleotidyltransferase - - - 0.0000000000000000006661 96.0
PYH3_k127_9157911_3 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000002298 64.0
PYH3_k127_9241014_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001419 601.0
PYH3_k127_9241014_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006264 270.0
PYH3_k127_9241014_2 Roadblock/LC7 domain - - - 0.0000007732 61.0
PYH3_k127_9267643_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 0.0000000000000000000000000000000000000000000000000000000001037 226.0
PYH3_k127_9267643_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.0000000000000000000000000000000000000000000000001446 181.0
PYH3_k127_9267643_2 domain, Protein - - - 0.000000000000000000000001207 121.0
PYH3_k127_9297911_0 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009336 430.0
PYH3_k127_9297911_1 metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 333.0
PYH3_k127_9297911_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008833 330.0
PYH3_k127_9297911_3 PFAM Stage II sporulation K06381 - - 0.000000000000000000000000000000000000000000000000000000000001478 224.0
PYH3_k127_9297911_4 His Kinase A (phospho-acceptor) domain - - - 0.00000000000000000000000000000000000000000000000000001767 210.0
PYH3_k127_9297911_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072,K12257 - - 0.0000000000000000000000000000000000000000000000000003609 194.0
PYH3_k127_9297911_6 cheY-homologous receiver domain K02657 - - 0.0000000000000000000000000005418 118.0
PYH3_k127_9297911_7 Preprotein translocase subunit K03210 - - 0.00000000000000000000001579 103.0
PYH3_k127_9297911_8 ATP-binding region ATPase domain protein - - - 0.000009978 57.0
PYH3_k127_935008_0 response to heat K03694,K03695 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 605.0
PYH3_k127_9435014_0 malic protein domain protein K00027,K00029 - 1.1.1.38,1.1.1.40 2.224e-281 890.0
PYH3_k127_9435014_1 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 1.083e-218 700.0
PYH3_k127_9435014_2 FAD linked oxidase domain protein K00102,K00104 - 1.1.2.4,1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 486.0
PYH3_k127_9435014_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 424.0
PYH3_k127_9435014_4 ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 319.0
PYH3_k127_9435014_5 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 311.0
PYH3_k127_9435014_6 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000234 297.0
PYH3_k127_9435014_7 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001849 278.0
PYH3_k127_9435014_8 CO dehydrogenase acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000001667 239.0
PYH3_k127_9435014_9 CO dehydrogenase acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000005428 229.0
PYH3_k127_9731356_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016875,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 490.0
PYH3_k127_9731356_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 375.0
PYH3_k127_9731356_2 Transglycosylase SLT domain K08307 - - 0.0000000000000000000000000000000000000000000000000005811 207.0
PYH3_k127_9731356_3 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000001555 188.0
PYH3_k127_9731356_4 - - - - 0.00000000000000000000000000001185 123.0
PYH3_k127_9731356_5 PFAM MotA TolQ ExbB proton channel K03561 - - 0.00000000000000000000000001935 113.0
PYH3_k127_9731356_6 Uncharacterized protein conserved in bacteria (DUF2135) - - - 0.000000000000000003513 98.0
PYH3_k127_9731356_7 TPR repeat - - - 0.000000009711 68.0
PYH3_k127_9731356_8 - - - - 0.000006373 49.0
PYH3_k127_9731356_9 OmpA family - - - 0.00002407 57.0
PYH3_k127_9738701_0 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 608.0
PYH3_k127_9738701_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 600.0
PYH3_k127_9738701_10 Periplasmic binding protein domain K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 389.0
PYH3_k127_9738701_11 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 348.0
PYH3_k127_9738701_12 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 334.0
PYH3_k127_9738701_13 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 289.0
PYH3_k127_9738701_14 PFAM ABC transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
PYH3_k127_9738701_15 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001042 261.0
PYH3_k127_9738701_16 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008599 243.0
PYH3_k127_9738701_17 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000000000000000000000000000000000000000000000005662 212.0
PYH3_k127_9738701_18 lysyltransferase activity K07027 - - 0.00000000000000000000000000000001957 141.0
PYH3_k127_9738701_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 601.0
PYH3_k127_9738701_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005109 539.0
PYH3_k127_9738701_4 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 521.0
PYH3_k127_9738701_5 Aldehyde dehydrogenase family K00128,K00131 - 1.2.1.3,1.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 445.0
PYH3_k127_9738701_6 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 441.0
PYH3_k127_9738701_7 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001953 435.0
PYH3_k127_9738701_8 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004834 439.0
PYH3_k127_9738701_9 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 399.0