Overview

ID MAG03217
Name PYH3_bin.21
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Nitrospiria
Order Nitrospirales
Family Nitrospiraceae
Genus Palsa-1315
Species
Assembly information
Completeness (%) 60.33
Contamination (%) 1.08
GC content (%) 57.0
N50 (bp) 6,640
Genome size (bp) 1,508,615

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1390

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_106836_0 succinyl-diaminopimelate desuccinylase activity - - - 4.3e-255 791.0
PYH3_k127_106836_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 1.015e-214 677.0
PYH3_k127_106836_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009096 440.0
PYH3_k127_106836_3 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 417.0
PYH3_k127_106836_4 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 338.0
PYH3_k127_106836_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 307.0
PYH3_k127_106836_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000003412 205.0
PYH3_k127_106836_8 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000004873 79.0
PYH3_k127_1099886_0 Uncharacterized protein family (UPF0051) K07033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 543.0
PYH3_k127_1099886_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000001561 243.0
PYH3_k127_1099886_2 PFAM ABC transporter K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000001687 240.0
PYH3_k127_1099886_4 Cys-tRNA(Pro) hydrolase activity K03976,K19055 - - 0.0000000000000000000000000000000000000000458 157.0
PYH3_k127_1099886_5 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000001119 70.0
PYH3_k127_1099886_6 Tfp pilus assembly protein FimV - - - 0.00001333 59.0
PYH3_k127_1113951_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 1.645e-229 718.0
PYH3_k127_1113951_1 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000000000000000000000000002033 224.0
PYH3_k127_1113951_2 UDP-4-amino-4-deoxy-L-arabinose aminotransferase K13010 - 2.6.1.102 0.00000000000000000000000000000000000004963 147.0
PYH3_k127_1231473_0 GHKL domain K13598 - 2.7.13.3 0.0 1155.0
PYH3_k127_1231473_1 Bacterial regulatory protein, Fis family K13599 - - 3.972e-208 651.0
PYH3_k127_1231473_2 Domain of unknown function (DUF1844) - - - 0.0000000000000000000000000000000000000282 147.0
PYH3_k127_1231473_3 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000006655 76.0
PYH3_k127_1237131_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0 1124.0
PYH3_k127_1237131_1 FAD binding domain K00239 - 1.3.5.1,1.3.5.4 2.107e-318 977.0
PYH3_k127_1237131_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 6.692e-226 704.0
PYH3_k127_1237131_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009107 460.0
PYH3_k127_1242024_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 589.0
PYH3_k127_1242024_1 Transcriptional regulator K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006673 300.0
PYH3_k127_1242024_2 Replication initiation factor K07467 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001782 283.0
PYH3_k127_1242024_3 3-isopropylmalate dehydrogenase activity K00030 - 1.1.1.41 0.0000000000000000000000000000000000000000004445 160.0
PYH3_k127_1242024_4 Cytochrome c K12263 - - 0.0000000000000000000000000000009519 126.0
PYH3_k127_1278421_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006491 451.0
PYH3_k127_1278421_1 AhpC/TSA family K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000009824 244.0
PYH3_k127_1278421_2 Cyclophilin-like K09143 - - 0.00000000000000000000000000000000000000000000000000000001656 201.0
PYH3_k127_1278421_3 - - - - 0.00000000000000000000000000000000000000000000000001737 184.0
PYH3_k127_1278421_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000005009 156.0
PYH3_k127_1278421_6 Protein of unknown function (DUF507) - - - 0.000000000000000000000000006982 112.0
PYH3_k127_1278421_7 Protein of unknown function (DUF507) - - - 0.00000000000000000000000004675 110.0
PYH3_k127_1278421_8 RNase_H superfamily K07502 - - 0.000000000000000005171 85.0
PYH3_k127_1278421_9 - - - - 0.000000002131 61.0
PYH3_k127_1304375_0 protein catabolic process K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 4.4e-323 995.0
PYH3_k127_1304375_1 O-methyltransferase activity K13571,K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 2.358e-257 799.0
PYH3_k127_1304375_2 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 473.0
PYH3_k127_1304375_3 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 415.0
PYH3_k127_1304375_4 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000008392 201.0
PYH3_k127_1304375_5 ThiS family K03154 - - 0.00000000000000000003022 92.0
PYH3_k127_1304375_6 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.0000000000000000005672 90.0
PYH3_k127_1304375_7 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03432 - 3.4.25.1 0.000000000000000005235 84.0
PYH3_k127_1328268_0 radical SAM domain protein - - - 0.0 998.0
PYH3_k127_1328268_1 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000001413 79.0
PYH3_k127_1337540_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 516.0
PYH3_k127_1337540_1 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003868 503.0
PYH3_k127_1337540_2 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001706 248.0
PYH3_k127_1337540_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000000000001781 229.0
PYH3_k127_1337540_4 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000733 199.0
PYH3_k127_1337540_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000142 199.0
PYH3_k127_1341962_0 pfkB family carbohydrate kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 555.0
PYH3_k127_1341962_1 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003643 415.0
PYH3_k127_1341962_2 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 415.0
PYH3_k127_1341962_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 411.0
PYH3_k127_1341962_4 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 400.0
PYH3_k127_1341962_5 Helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006873 376.0
PYH3_k127_1341962_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001034 280.0
PYH3_k127_1341962_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004461 263.0
PYH3_k127_1363818_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 1.167e-244 758.0
PYH3_k127_1363818_1 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007716 469.0
PYH3_k127_1363818_10 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000009347 161.0
PYH3_k127_1363818_11 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.0000000000000000000000000000000000000000002592 160.0
PYH3_k127_1363818_12 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000004346 130.0
PYH3_k127_1363818_13 Belongs to the universal ribosomal protein uL29 family K02904 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000001106 76.0
PYH3_k127_1363818_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 394.0
PYH3_k127_1363818_3 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 341.0
PYH3_k127_1363818_4 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003654 289.0
PYH3_k127_1363818_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000001809 254.0
PYH3_k127_1363818_6 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006617 229.0
PYH3_k127_1363818_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.0000000000000000000000000000000000000000000000000001256 186.0
PYH3_k127_1363818_8 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000000002421 185.0
PYH3_k127_1363818_9 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000001655 164.0
PYH3_k127_1375612_0 Protein involved in outer membrane biogenesis K07290 - - 9.747e-204 642.0
PYH3_k127_1375612_1 Metallopeptidase family M24 K01262 - 3.4.11.9 5.522e-194 611.0
PYH3_k127_1375612_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000001154 262.0
PYH3_k127_1403719_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 565.0
PYH3_k127_1403719_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 522.0
PYH3_k127_1403719_2 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 467.0
PYH3_k127_1403719_3 Ribosomal L32p protein family K02911 - - 0.0000000000000004637 79.0
PYH3_k127_1403719_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.0000003622 52.0
PYH3_k127_1496211_0 cobalamin synthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005475 424.0
PYH3_k127_1496211_1 Acid phosphatase homologues K19302 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000001002 229.0
PYH3_k127_1534221_0 CHASE3 domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001291 586.0
PYH3_k127_1534221_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004906 305.0
PYH3_k127_1534221_2 cheY-homologous receiver domain - - - 0.00000000000000000004511 89.0
PYH3_k127_1547676_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000000000000001343 192.0
PYH3_k127_1547676_1 regulation of translation K03530 - - 0.000000000000000000000000000000000000001497 151.0
PYH3_k127_1547676_3 PFAM nuclease (SNase domain protein) - - - 0.000000000724 63.0
PYH3_k127_1547676_4 nuclease K01174 - 3.1.31.1 0.00000007661 55.0
PYH3_k127_1547676_5 deoxyribonuclease I activity K01150 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005575,GO:0005576,GO:0005623,GO:0006139,GO:0006259,GO:0006308,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016787,GO:0016788,GO:0016888,GO:0016893,GO:0019439,GO:0034641,GO:0034655,GO:0042597,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360,GO:1901361,GO:1901575 3.1.21.1 0.0000002439 53.0
PYH3_k127_1623810_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K01147,K12573 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 614.0
PYH3_k127_1623810_1 glucose-6-phosphate dehydrogenase activity K00036 - 1.1.1.363,1.1.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005573 512.0
PYH3_k127_1623810_2 Required for a late step of 50S ribosomal subunit assembly. Has GTPase activity K14540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 377.0
PYH3_k127_1623810_3 Copper resistance protein B precursor (CopB) K07233 - - 0.00000000000000000000000000000000000000000000000000000005329 198.0
PYH3_k127_1623810_4 ATPase activity - - - 0.000000000000000000000000000000000000000000000009058 178.0
PYH3_k127_1623810_6 - - - - 0.00000000000000004905 82.0
PYH3_k127_1633198_0 1,4-alpha-glucan branching enzyme activity K00700,K01236 GO:0000271,GO:0003674,GO:0003824,GO:0003844,GO:0005975,GO:0005976,GO:0005977,GO:0005978,GO:0006073,GO:0006091,GO:0006112,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009250,GO:0009987,GO:0015980,GO:0016051,GO:0016740,GO:0016757,GO:0016758,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044042,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0055114,GO:0071704,GO:1901576 2.4.1.18,3.2.1.141 1.219e-309 965.0
PYH3_k127_1633198_1 Peptidase M15 K02395 - - 0.00000000000000000000000000000000000000000000000000000000000065 216.0
PYH3_k127_1633198_2 phosphorelay signal transduction system K02535 - 3.5.1.108 0.000000002666 59.0
PYH3_k127_1646994_0 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1160.0
PYH3_k127_1646994_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 598.0
PYH3_k127_1646994_2 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004294 544.0
PYH3_k127_1646994_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 465.0
PYH3_k127_1646994_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 457.0
PYH3_k127_1646994_5 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 387.0
PYH3_k127_1655192_0 Radical SAM superfamily K04069 - 1.97.1.4 4.424e-201 629.0
PYH3_k127_1655192_1 Protein of unknown function (DUF1614) - - - 0.000000000000000000000000000000000000000000000000000001421 199.0
PYH3_k127_1655192_3 Mut7-C RNAse domain K09122 - - 0.000000000000000000000001036 109.0
PYH3_k127_1656302_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 2.184e-277 859.0
PYH3_k127_1656302_1 Evidence 2b Function of strongly homologous gene - - - 6.018e-210 656.0
PYH3_k127_1656302_2 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 1.395e-206 657.0
PYH3_k127_1656302_3 Histidyl-tRNA synthetase K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 436.0
PYH3_k127_1656302_4 Lysin motif K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 350.0
PYH3_k127_1698978_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000498 331.0
PYH3_k127_1698978_1 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000004575 122.0
PYH3_k127_1698978_2 (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase activity - - - 0.000000000000000000000000001466 112.0
PYH3_k127_1698978_3 - - - - 0.000000000000000000000000004843 115.0
PYH3_k127_170220_0 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.527e-204 640.0
PYH3_k127_170220_1 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005364 351.0
PYH3_k127_170220_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 317.0
PYH3_k127_170220_3 ACT domain K01653 - 2.2.1.6 0.00000000000000000000000000000000000000001764 153.0
PYH3_k127_1709977_0 2-methylcitrate dehydratase activity K01720 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009268,GO:0009628,GO:0009987,GO:0010447,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019679,GO:0019752,GO:0030312,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0046459,GO:0047547,GO:0050896,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.79 1.148e-216 681.0
PYH3_k127_1709977_1 Belongs to the citrate synthase family K01647,K01659 GO:0003674,GO:0003824,GO:0004108,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0016740,GO:0016746,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0032787,GO:0036440,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0046459,GO:0046912,GO:0050440,GO:0055114,GO:0071704 2.3.3.1,2.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 518.0
PYH3_k127_1709977_11 - - - - 0.0000000000000000008529 92.0
PYH3_k127_1709977_12 Cytochrome c K12263 - - 0.0000000000000003626 84.0
PYH3_k127_1709977_13 Protein conserved in bacteria - - - 0.0000000000444 73.0
PYH3_k127_1709977_14 Belongs to the SOS response-associated peptidase family - - - 0.000000001674 62.0
PYH3_k127_1709977_15 Helix-hairpin-helix motif - - - 0.000001973 53.0
PYH3_k127_1709977_2 methylisocitrate lyase activity K03417 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006091,GO:0006113,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0046421,GO:0046459,GO:0046872,GO:0055114,GO:0071704,GO:0072329,GO:1901575 4.1.3.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 362.0
PYH3_k127_1709977_3 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007309 371.0
PYH3_k127_1709977_4 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.0000000000000000000000000000000000000000000000000001501 192.0
PYH3_k127_1709977_5 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000001244 170.0
PYH3_k127_1709977_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000000001194 160.0
PYH3_k127_1709977_7 Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000002209 121.0
PYH3_k127_1709977_8 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000000000000002976 114.0
PYH3_k127_1709977_9 - - - - 0.000000000000000000000005637 104.0
PYH3_k127_1739479_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 3.762e-274 852.0
PYH3_k127_1739479_1 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 423.0
PYH3_k127_1739479_2 Type II/IV secretion system protein K02454,K02652 - - 0.0000000000000000000000008075 106.0
PYH3_k127_1803085_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001922 270.0
PYH3_k127_1803085_1 Glycoprotease family K14742 - - 0.0000000000000000000000000000000000000000000000000001426 192.0
PYH3_k127_1803085_2 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000000000000000000000004965 176.0
PYH3_k127_1803085_3 Protein of unknown function (DUF465) K09794 - - 0.000000000000000005032 87.0
PYH3_k127_1808222_0 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 4.378e-202 638.0
PYH3_k127_1808222_1 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 2.715e-200 629.0
PYH3_k127_1808222_2 NeuB family K03856 - 2.5.1.54 3.268e-200 625.0
PYH3_k127_1808222_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004055 555.0
PYH3_k127_1808222_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 548.0
PYH3_k127_1808222_5 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 436.0
PYH3_k127_1808222_6 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006961 282.0
PYH3_k127_1808222_7 Phosphate acyltransferases K00655 - 2.3.1.51 0.000000000000000000000000005719 111.0
PYH3_k127_1872953_0 Aldehyde dehydrogenase family - - - 3.749e-218 685.0
PYH3_k127_1872953_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 8.892e-197 618.0
PYH3_k127_1872953_2 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004577 553.0
PYH3_k127_1872953_3 arginine decarboxylase activity K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004009 351.0
PYH3_k127_1872953_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 295.0
PYH3_k127_1887690_0 radical SAM domain protein - - - 0.0 1083.0
PYH3_k127_1887690_1 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 352.0
PYH3_k127_1887690_2 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.000000000000000000000000000000000000000000000000000000000000000001627 228.0
PYH3_k127_1887690_3 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.0000000000000001413 79.0
PYH3_k127_1891941_0 transferase activity, transferring hexosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003619 416.0
PYH3_k127_1891941_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000004328 176.0
PYH3_k127_1891941_2 DNA-templated transcription, initiation K03088 - - 0.000000000000000000000000000000000000000954 149.0
PYH3_k127_1940430_0 PFAM Copper resistance D K07245 - - 7.025e-295 918.0
PYH3_k127_1940430_1 transposition, DNA-mediated - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 357.0
PYH3_k127_1940430_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004674 247.0
PYH3_k127_1940430_3 - - - - 0.000000000000000000000000000000000000000000000000000000005267 205.0
PYH3_k127_1940430_4 - - - - 0.0000000000000000000000000000000000000000000000000003264 190.0
PYH3_k127_1940430_5 PFAM Copper resistance protein CopC K07156 - - 0.00000000000000000000000000000000000000000000000002034 183.0
PYH3_k127_1940430_6 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.00000000000000001782 84.0
PYH3_k127_1944194_0 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004822 427.0
PYH3_k127_1944194_1 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 331.0
PYH3_k127_1944194_10 PFAM nuclease (SNase domain protein) - - - 0.0000000000000008636 81.0
PYH3_k127_1944194_11 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.0000000000001556 74.0
PYH3_k127_1944194_12 Sel1-like repeats. - - - 0.00000002137 56.0
PYH3_k127_1944194_14 zinc ion binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000209 51.0
PYH3_k127_1944194_15 Staphylococcal nuclease homologues K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.00003331 46.0
PYH3_k127_1944194_2 Phage integrase, N-terminal SAM-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008259 308.0
PYH3_k127_1944194_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000006676 226.0
PYH3_k127_1944194_4 Transglycosylase SLT domain - - - 0.0000000000000000000000000000000000000000000000000000000002343 212.0
PYH3_k127_1944194_5 - - - - 0.00000000000000000000000000000000001426 143.0
PYH3_k127_1944194_6 - - - - 0.0000000000000000000000000000000003306 136.0
PYH3_k127_1944194_7 Phage integrase SAM-like domain - - - 0.00000000000000000000000001442 111.0
PYH3_k127_1944194_9 Replication initiation factor K07467 - - 0.000000000000000000002918 98.0
PYH3_k127_194483_0 NmrA-like family K00091 - 1.1.1.219 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 570.0
PYH3_k127_194483_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003389 506.0
PYH3_k127_194483_2 Carotenoid biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 373.0
PYH3_k127_194483_3 Cytochrome c K03611 - - 0.0000000000007309 70.0
PYH3_k127_2038050_0 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 483.0
PYH3_k127_2038050_1 pectinesterase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 435.0
PYH3_k127_2038050_2 Zinc-uptake complex component A periplasmic K09815,K09818 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004067 378.0
PYH3_k127_2038050_3 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003542 252.0
PYH3_k127_2038050_4 protein trimerization - - - 0.00000000000000000000000000000000000000000000000000002125 192.0
PYH3_k127_2038050_5 AAA domain, putative AbiEii toxin, Type IV TA system K09817,K09820 - - 0.000000000000000000000000000000000000000568 150.0
PYH3_k127_2064276_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 3.8e-206 657.0
PYH3_k127_2064276_1 Glycosyltransferase like family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007668 409.0
PYH3_k127_2064276_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001295 245.0
PYH3_k127_2064276_3 lipid-A-disaccharide synthase activity - - - 0.0000000000000000000000000000000000000005272 153.0
PYH3_k127_2064276_4 S23 ribosomal protein - - - 0.0000000000000000000000000000000003524 135.0
PYH3_k127_2064276_5 PAP2 superfamily K19302 - 3.6.1.27 0.00000000000000000000000000000000312 138.0
PYH3_k127_2154316_0 metalloendopeptidase activity K08602 - - 1.559e-237 746.0
PYH3_k127_2154316_1 denitrification pathway - - - 6.646e-228 715.0
PYH3_k127_2154316_2 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007575 535.0
PYH3_k127_2154316_3 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 474.0
PYH3_k127_2154316_4 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006663 407.0
PYH3_k127_2154316_5 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005022 286.0
PYH3_k127_2154316_6 HemY protein K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000005384 177.0
PYH3_k127_2154316_8 Small metal-binding protein - - - 0.000000000000000002261 89.0
PYH3_k127_220274_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001721 349.0
PYH3_k127_220274_1 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000002219 220.0
PYH3_k127_2228782_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0 1314.0
PYH3_k127_2228782_1 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 479.0
PYH3_k127_2237254_0 Belongs to the aldehyde dehydrogenase family K00130,K00135,K00146,K22187 - 1.2.1.16,1.2.1.20,1.2.1.39,1.2.1.79,1.2.1.8 2.525e-252 790.0
PYH3_k127_2237254_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 594.0
PYH3_k127_2237254_10 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.000000000000000003107 93.0
PYH3_k127_2237254_2 Protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 554.0
PYH3_k127_2237254_3 nitric oxide reductase activity K03809 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006727 394.0
PYH3_k127_2237254_4 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 372.0
PYH3_k127_2237254_5 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007283 271.0
PYH3_k127_2237254_6 Helix-hairpin-helix domain K04477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006651 281.0
PYH3_k127_2237254_7 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.00000000000000000000000000000000000000000000000000000000000001359 218.0
PYH3_k127_2237254_8 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.0000000000000000000000000000000000007137 153.0
PYH3_k127_2237254_9 Endonuclease containing a URI domain K07461 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004520,GO:0004527,GO:0004529,GO:0004536,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008296,GO:0008408,GO:0009987,GO:0016787,GO:0016788,GO:0016796,GO:0016895,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 - 0.000000000000000000000000003378 113.0
PYH3_k127_226378_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1500.0
PYH3_k127_226378_1 Elongator protein 3, MiaB family, Radical SAM - - - 3.314e-316 973.0
PYH3_k127_226378_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006731 412.0
PYH3_k127_2283847_0 PP-loop family K21947 - 2.8.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 509.0
PYH3_k127_2283847_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 443.0
PYH3_k127_2283847_2 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000001585 239.0
PYH3_k127_2283847_3 ATP-independent chaperone mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000001994 197.0
PYH3_k127_2283847_4 MarC family integral membrane protein K05595 - - 0.0003852 45.0
PYH3_k127_2459166_0 Nadh flavin oxidoreductase nadh oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002468 479.0
PYH3_k127_2459166_1 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007638 466.0
PYH3_k127_2459166_2 PFAM flavin reductase domain protein, FMN-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005112 276.0
PYH3_k127_2459166_4 Domain of unknown function (DUF5069) - - - 0.00001791 49.0
PYH3_k127_2459166_5 - - - - 0.0003912 43.0
PYH3_k127_2470409_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002792 530.0
PYH3_k127_2470409_1 Cation transporter/ATPase, N-terminus - - - 0.000000000000000000000000000000000000000000000000000000000003629 212.0
PYH3_k127_2470409_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000001596 109.0
PYH3_k127_2490979_0 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 1.534e-245 765.0
PYH3_k127_2490979_1 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 2.799e-213 675.0
PYH3_k127_2490979_2 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 1.381e-201 639.0
PYH3_k127_2490979_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 545.0
PYH3_k127_2505383_0 sulfate adenylyltransferase (ATP) activity K00860,K00955,K00956 - 2.7.1.25,2.7.7.4 1.299e-237 740.0
PYH3_k127_2505383_1 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 504.0
PYH3_k127_2505383_2 Glycosyl transferase family, a/b domain K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 437.0
PYH3_k127_2505383_3 sulfate reduction K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001716 372.0
PYH3_k127_2505383_4 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001648 275.0
PYH3_k127_2507301_0 4 iron, 4 sulfur cluster binding K00113,K00176,K05524,K13795,K13796 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0022900,GO:0043167,GO:0043169,GO:0044237,GO:0044464,GO:0045333,GO:0046872,GO:0048037,GO:0051536,GO:0051540,GO:0055114,GO:0071944 1.1.5.3,1.2.7.3 7.214e-214 671.0
PYH3_k127_2507301_1 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 335.0
PYH3_k127_2507301_2 AhpC/TSA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 293.0
PYH3_k127_2507301_3 Protein of unknown function (DUF3501) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005462 265.0
PYH3_k127_2507301_4 cell redox homeostasis K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000000000000003825 205.0
PYH3_k127_2507301_5 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000000000000008195 91.0
PYH3_k127_2507301_6 - - - - 0.00000000006606 64.0
PYH3_k127_251665_0 Rubrerythrin K22405 - 1.6.3.4 0.0 1217.0
PYH3_k127_251665_1 Iron-sulfur cluster-binding domain - - - 1.754e-236 733.0
PYH3_k127_2549115_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002538 244.0
PYH3_k127_2549115_2 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000003151 115.0
PYH3_k127_2576600_0 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 413.0
PYH3_k127_2576600_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000008958 264.0
PYH3_k127_2576600_2 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000149 224.0
PYH3_k127_2576600_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000158 44.0
PYH3_k127_2579003_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1143.0
PYH3_k127_2579003_1 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 384.0
PYH3_k127_2579003_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000000000000004609 247.0
PYH3_k127_2579003_3 photosystem II stabilization K02237 - - 0.00000000000000000000000000000000000000000000000000000000000000000003601 239.0
PYH3_k127_2582922_0 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 491.0
PYH3_k127_2582922_1 tRNA processing K04075,K14058,K21947 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.1.15,6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 387.0
PYH3_k127_2582922_2 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000000000000003303 188.0
PYH3_k127_2582922_3 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000001228 168.0
PYH3_k127_2598290_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005725 331.0
PYH3_k127_2598290_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000003091 227.0
PYH3_k127_2610310_0 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001718 490.0
PYH3_k127_2610310_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000001727 261.0
PYH3_k127_2610310_2 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000002288 174.0
PYH3_k127_2610310_4 coenzyme binding K07071 - - 0.000000000000000001188 88.0
PYH3_k127_2623413_0 Sigma-54 interaction domain K07714 - - 1.795e-217 684.0
PYH3_k127_2623413_1 4-alpha-glucanotransferase K00705,K06044 - 2.4.1.25,5.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 595.0
PYH3_k127_2623413_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 471.0
PYH3_k127_2623413_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005414 256.0
PYH3_k127_2623413_4 Protein of unknown function (DUF2490) - - - 0.0000000000000000000000000000000000000000000000001532 186.0
PYH3_k127_2623413_5 sequence-specific DNA binding - - - 0.000000000000000000000000000002769 124.0
PYH3_k127_268569_0 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 535.0
PYH3_k127_268569_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005579 298.0
PYH3_k127_268569_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001387 190.0
PYH3_k127_2700500_0 Belongs to the carbamoyltransferase HypF family K04656 - - 9.877e-198 635.0
PYH3_k127_2700500_1 TIGRFAM hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004081 521.0
PYH3_k127_2700500_2 AIR synthase related protein, N-terminal domain K04655 - - 0.000000000000000000000000000000000002362 140.0
PYH3_k127_2700500_3 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.00000000000000000008584 91.0
PYH3_k127_271861_0 FAD binding domain K00278 - 1.4.3.16 8.141e-265 824.0
PYH3_k127_271861_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005678 430.0
PYH3_k127_271861_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 292.0
PYH3_k127_271861_3 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002752 265.0
PYH3_k127_271861_4 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046820,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000001002 241.0
PYH3_k127_2764849_0 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1286.0
PYH3_k127_2764849_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 576.0
PYH3_k127_2764849_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003341 349.0
PYH3_k127_2764849_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000001656 221.0
PYH3_k127_2775539_0 phospholipase Carboxylesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 547.0
PYH3_k127_2775539_1 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 436.0
PYH3_k127_2775539_2 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 352.0
PYH3_k127_2808391_0 Lysin motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 521.0
PYH3_k127_2808391_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 457.0
PYH3_k127_2808391_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 382.0
PYH3_k127_2808391_3 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 349.0
PYH3_k127_2808391_4 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 0.0000000000000000000000000000003811 129.0
PYH3_k127_282602_0 Bacterial extracellular solute-binding protein K02048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009426 489.0
PYH3_k127_282602_1 PFAM binding-protein-dependent transport systems inner membrane component K02046,K15496 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 419.0
PYH3_k127_282602_2 Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 420.0
PYH3_k127_282602_3 Sulfate ABC transporter, inner membrane subunit CysW K02047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 414.0
PYH3_k127_282602_4 Uncharacterized protein conserved in bacteria (DUF2325) - - - 0.000000000000000000000000000009948 120.0
PYH3_k127_2868723_0 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 560.0
PYH3_k127_2868723_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 432.0
PYH3_k127_2868723_2 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 385.0
PYH3_k127_2868723_4 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.00000000000000001782 84.0
PYH3_k127_2887192_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798,K04076,K13525,K17681 - 3.4.21.53 6.364e-275 856.0
PYH3_k127_2887192_1 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000895 384.0
PYH3_k127_2887192_10 ACT domain - - - 0.0000002158 56.0
PYH3_k127_2887192_2 two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07713 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006299 307.0
PYH3_k127_2887192_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000006206 238.0
PYH3_k127_2887192_4 cellular manganese ion homeostasis - - - 0.00000000000000000000000000000000000000000000000000000000000000001435 227.0
PYH3_k127_2887192_6 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000003249 146.0
PYH3_k127_2887192_7 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000008187 158.0
PYH3_k127_2887192_8 integral membrane protein - - - 0.0000000000000000000000000000000000001615 146.0
PYH3_k127_2887192_9 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.000000000000000000001521 97.0
PYH3_k127_2945702_0 PhoQ Sensor - - - 2.612e-237 764.0
PYH3_k127_2945702_1 long-chain fatty acid transporting porin activity K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006142 598.0
PYH3_k127_2945702_2 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000008353 150.0
PYH3_k127_2972182_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.596e-228 713.0
PYH3_k127_2972182_1 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 291.0
PYH3_k127_2974772_0 Lipocalin-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002907 463.0
PYH3_k127_2974772_1 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005376 445.0
PYH3_k127_2974772_2 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 297.0
PYH3_k127_2974772_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000001253 224.0
PYH3_k127_297748_0 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 402.0
PYH3_k127_297748_1 biopolymer transport protein K03559 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000001772 182.0
PYH3_k127_297748_2 - K12065 - - 0.000000000000000000000000000000000000001237 154.0
PYH3_k127_297748_3 MotA/TolQ/ExbB proton channel family - - - 0.0000000000000000000000001887 108.0
PYH3_k127_297748_4 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.000008738 57.0
PYH3_k127_297748_5 - - - - 0.000009081 50.0
PYH3_k127_2995060_0 Glycosyl hydrolase family 57 - - - 0.0 1063.0
PYH3_k127_2995060_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007014 585.0
PYH3_k127_2995060_2 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000000000000001899 108.0
PYH3_k127_2995060_3 PP-loop family K21947 - 2.8.1.15 0.00000000006239 63.0
PYH3_k127_3010066_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 3.334e-233 737.0
PYH3_k127_3010066_1 photosynthesis K02453,K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 560.0
PYH3_k127_3010066_2 Dimerisation domain - - - 0.00000000000000000000000000000000000000000000001493 185.0
PYH3_k127_3010066_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000005473 96.0
PYH3_k127_3010066_6 Protein of unknown function, DUF393 - - - 0.00003237 53.0
PYH3_k127_3069316_0 amine dehydrogenase activity K01406 - 3.4.24.40 2.69e-209 655.0
PYH3_k127_3069316_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004518 346.0
PYH3_k127_3069316_10 PFAM nuclease (SNase domain protein) - - - 0.000007112 48.0
PYH3_k127_3069316_2 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000006778 222.0
PYH3_k127_3069316_3 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000004852 97.0
PYH3_k127_3069316_4 Sigma-54 interaction domain K07714 - - 0.0000000000000000001113 90.0
PYH3_k127_3069316_5 Beta-lactamase superfamily domain - - - 0.00000000000000000302 85.0
PYH3_k127_3069316_6 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000162 81.0
PYH3_k127_3069316_7 nuclease K01174 GO:0003674,GO:0003824,GO:0004518,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0090305,GO:1901360,GO:1901361,GO:1901575 3.1.31.1 0.00000000004577 64.0
PYH3_k127_3069316_9 - - - - 0.000003198 55.0
PYH3_k127_3149517_0 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005245 444.0
PYH3_k127_3149517_1 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 356.0
PYH3_k127_3149517_2 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 316.0
PYH3_k127_3149517_3 mannosylglycerate metabolic process K05947,K07026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0050897 2.4.1.217,3.1.3.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 305.0
PYH3_k127_3149517_4 protein conserved in bacteria K09859 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003093 253.0
PYH3_k127_3149517_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000227 243.0
PYH3_k127_316375_0 Lysine-2,3-aminomutase K01843 - 5.4.3.2 4.37e-213 666.0
PYH3_k127_316375_1 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 1.707e-204 640.0
PYH3_k127_316375_2 - - - - 6.704e-194 616.0
PYH3_k127_316375_3 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 410.0
PYH3_k127_316375_4 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008015 298.0
PYH3_k127_316375_5 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 287.0
PYH3_k127_316375_6 protein disulfide oxidoreductase activity K07390 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000003368 197.0
PYH3_k127_316375_9 glutathione transferase activity K00799 - 2.5.1.18 0.00000000000000000000000000002623 118.0
PYH3_k127_319071_0 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 3.282e-264 815.0
PYH3_k127_319071_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 1.403e-226 707.0
PYH3_k127_319071_10 YCII-related domain K09780 - - 0.00000000000000002345 85.0
PYH3_k127_319071_11 Tetratricopeptide repeat - - - 0.0000001202 64.0
PYH3_k127_319071_2 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 7.594e-200 629.0
PYH3_k127_319071_3 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009954 494.0
PYH3_k127_319071_4 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 306.0
PYH3_k127_319071_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
PYH3_k127_319071_6 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000004933 250.0
PYH3_k127_319071_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.0000000000000000000000000000000000000000000000000000001682 195.0
PYH3_k127_319071_8 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000000000004562 178.0
PYH3_k127_319071_9 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000005006 130.0
PYH3_k127_3191314_0 COGs COG0531 Amino acid transporter K03294,K20265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003046 278.0
PYH3_k127_3191314_1 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000007001 252.0
PYH3_k127_3191314_2 Radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000003073 224.0
PYH3_k127_3191314_3 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000003275 218.0
PYH3_k127_33789_0 E1-E2 ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 5.755e-248 780.0
PYH3_k127_33789_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 381.0
PYH3_k127_33789_2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001257 309.0
PYH3_k127_33789_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000245 276.0
PYH3_k127_33789_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.000000000000000000000000000000000000000000000000009655 185.0
PYH3_k127_33789_5 - - - - 0.0000000000000000000000000000001702 132.0
PYH3_k127_3382675_0 exonuclease activity K16899 - 3.6.4.12 4.918e-258 831.0
PYH3_k127_3382675_1 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 473.0
PYH3_k127_341060_0 metallopeptidase activity K01993,K13408,K16922 - - 2.735e-221 708.0
PYH3_k127_341060_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000000000000000000001311 214.0
PYH3_k127_341060_2 domain, Protein K13735,K15125,K15531 - 3.2.1.156 0.0005673 46.0
PYH3_k127_345656_0 Endoribonuclease that initiates mRNA decay K18682 - - 4.131e-256 798.0
PYH3_k127_345656_1 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 480.0
PYH3_k127_345656_2 YmdB-like protein K09769 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 436.0
PYH3_k127_345656_3 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 310.0
PYH3_k127_345656_4 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.0000000000000000000000000001754 116.0
PYH3_k127_345656_5 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000001147 59.0
PYH3_k127_3498176_1 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 443.0
PYH3_k127_3498176_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000004343 104.0
PYH3_k127_3519541_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 1.745e-199 632.0
PYH3_k127_3519541_1 phosphonoacetaldehyde hydrolase activity K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000004873 196.0
PYH3_k127_3519541_3 response regulator - - - 0.000000000000282 76.0
PYH3_k127_3519812_0 Transglycosylase SLT domain K08309 - - 2.766e-249 794.0
PYH3_k127_3519812_1 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001592 285.0
PYH3_k127_3519812_2 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000000698 127.0
PYH3_k127_3712556_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 5.401e-256 790.0
PYH3_k127_3712556_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007433 571.0
PYH3_k127_3712556_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 425.0
PYH3_k127_3712556_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000463 288.0
PYH3_k127_3712556_4 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.00000000000000000000000000000000000000000000000000000000000000004117 230.0
PYH3_k127_3712556_5 Oxidoreductase - - - 0.00000000000000000000000000000000000000000000001124 172.0
PYH3_k127_3712556_7 HNH nucleases - - - 0.00000007699 56.0
PYH3_k127_3721585_0 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002129 284.0
PYH3_k127_3721585_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000647 224.0
PYH3_k127_3721585_3 spore germination - - - 0.0000000000000000000000000003467 115.0
PYH3_k127_3724843_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 6.753e-319 985.0
PYH3_k127_3724843_1 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 1.583e-218 690.0
PYH3_k127_3724843_2 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 338.0
PYH3_k127_3724843_3 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002233 299.0
PYH3_k127_3724843_4 metalloendopeptidase activity - - - 0.00000000000000000000000000000000000000000000002288 174.0
PYH3_k127_3738681_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002831 284.0
PYH3_k127_3738681_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.000000000000000000000000000000000000002317 155.0
PYH3_k127_3738681_2 Zinc-binding dehydrogenase K13979 - - 0.0000000000000000000003186 96.0
PYH3_k127_3738681_3 zinc ion binding K00859,K09862 GO:0003674,GO:0004857,GO:0005488,GO:0008150,GO:0008270,GO:0008657,GO:0010911,GO:0030234,GO:0032780,GO:0042030,GO:0043086,GO:0043167,GO:0043169,GO:0043462,GO:0044092,GO:0046872,GO:0046914,GO:0050790,GO:0051336,GO:0051346,GO:0060589,GO:0060590,GO:0065007,GO:0065009,GO:0072586,GO:0098772,GO:2000371,GO:2000372 2.7.1.24 0.000000000000001256 78.0
PYH3_k127_3767297_0 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2730.0
PYH3_k127_3767297_1 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007567 559.0
PYH3_k127_3767297_2 Polyprenyl synthetase K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 520.0
PYH3_k127_377018_0 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 484.0
PYH3_k127_377018_1 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 356.0
PYH3_k127_377018_2 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003027 309.0
PYH3_k127_377018_3 cellular response to DNA damage stimulus K07340 - - 0.000000000000000000000000000000000000000000000002649 176.0
PYH3_k127_377018_4 peptidyl-tyrosine sulfation - - - 0.000000000000000000005054 97.0
PYH3_k127_3792146_0 NADH-quinone oxidoreductase K00341 - 1.6.5.3 0.0 1014.0
PYH3_k127_3792146_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 2.678e-235 737.0
PYH3_k127_3792146_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.226e-209 663.0
PYH3_k127_3792146_3 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000002576 201.0
PYH3_k127_3792146_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.000000000000000000000000000000000000006185 147.0
PYH3_k127_3792146_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.0000000000154 64.0
PYH3_k127_3814988_0 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002084 510.0
PYH3_k127_3814988_1 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007029 429.0
PYH3_k127_3814988_2 Pfam:DUF989 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004786 259.0
PYH3_k127_3814988_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000002736 230.0
PYH3_k127_3816427_0 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1098.0
PYH3_k127_3816427_1 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 1.397e-282 876.0
PYH3_k127_3816427_2 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 9.157e-219 692.0
PYH3_k127_3816427_3 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 394.0
PYH3_k127_3816427_4 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000003877 128.0
PYH3_k127_3816427_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000000000003138 96.0
PYH3_k127_3816427_6 Bacterial protein of unknown function (DUF898) - - - 0.0008767 48.0
PYH3_k127_3826250_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 491.0
PYH3_k127_3826250_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 387.0
PYH3_k127_382688_0 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 299.0
PYH3_k127_382688_1 Domain of unknown function (DUF4410) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009004 256.0
PYH3_k127_382688_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000004228 183.0
PYH3_k127_382688_3 Sulfatase K01130 - 3.1.6.1 0.0000000000000000000000000000000003646 135.0
PYH3_k127_382688_4 - - - - 0.0000000000000000000000000000001253 127.0
PYH3_k127_382688_5 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000002939 122.0
PYH3_k127_382688_6 Sulfatase-modifying factor enzyme 1 - - - 0.00000000000007755 71.0
PYH3_k127_383293_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787,K15726 - - 0.0 1258.0
PYH3_k127_383293_1 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 1.857e-267 827.0
PYH3_k127_383293_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 311.0
PYH3_k127_383293_3 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003865 248.0
PYH3_k127_3842823_0 Cytochrome c K12263 - - 2.49e-254 789.0
PYH3_k127_3842823_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001794 549.0
PYH3_k127_3842823_2 Cytochrome C oxidase, cbb3-type, subunit III K19713 - 1.8.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006 377.0
PYH3_k127_3842823_3 Cytochrome c K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000638 240.0
PYH3_k127_3842823_4 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000000000000008472 215.0
PYH3_k127_3842823_5 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.00000000000000000000000000000000000000000000000000000000001745 207.0
PYH3_k127_3842823_6 diguanylate cyclase - - - 0.0000000000000000000000000000000000000003964 153.0
PYH3_k127_3891577_0 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002056 490.0
PYH3_k127_3891577_1 signal-transduction protein containing cAMP-binding and CBS domains K00031,K14446 - 1.1.1.42,1.3.1.85 0.0000000000000000000000000000000000000000000000000000000000000000002084 237.0
PYH3_k127_3891577_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.00000000000000000000000000000000000000000000000003322 183.0
PYH3_k127_3919234_0 (ABC) transporter K15738 - - 3.331e-279 869.0
PYH3_k127_3919234_1 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 567.0
PYH3_k127_3919234_10 Acetyltransferase (GNAT) domain - - - 0.00000000000000007997 82.0
PYH3_k127_3919234_12 - - - - 0.00000000004492 69.0
PYH3_k127_3919234_13 acetyltransferase K18816 GO:0003674,GO:0003824,GO:0008080,GO:0008150,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0034069,GO:0042221,GO:0046677,GO:0047663,GO:0050896 2.3.1.82 0.00000004716 54.0
PYH3_k127_3919234_14 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000001356 51.0
PYH3_k127_3919234_2 epimerase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 490.0
PYH3_k127_3919234_3 symporter activity K03307,K14387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 419.0
PYH3_k127_3919234_4 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 331.0
PYH3_k127_3919234_5 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 292.0
PYH3_k127_3919234_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000002069 258.0
PYH3_k127_3919234_7 Serine hydrolase K07002,K19073 - 1.3.1.75 0.000000000000000000000000000000000000000000000000000000000001397 214.0
PYH3_k127_3919234_8 Methylase involved in ubiquinone menaquinone biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000003721 207.0
PYH3_k127_3919234_9 - - - - 0.0000000000000000000000000000000000000000000000001479 180.0
PYH3_k127_3934783_0 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006949 440.0
PYH3_k127_3934783_1 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001856 250.0
PYH3_k127_3934783_2 Cytochrome c K00405 - - 0.000000000000000000000000000000000000000000001085 170.0
PYH3_k127_3935361_0 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 591.0
PYH3_k127_3935361_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 476.0
PYH3_k127_3998999_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138,K19585 - - 0.0 1508.0
PYH3_k127_3998999_1 Major facilitator Superfamily K08218 - - 3.708e-252 788.0
PYH3_k127_3998999_10 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004866 270.0
PYH3_k127_3998999_11 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001634 261.0
PYH3_k127_3998999_12 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001754 246.0
PYH3_k127_3998999_13 protein disulfide oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000124 237.0
PYH3_k127_3998999_14 oxidation-reduction process - - - 0.000000000000000000000000000000000000000000000000000000000000004239 218.0
PYH3_k127_3998999_15 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000004526 189.0
PYH3_k127_3998999_16 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000007428 169.0
PYH3_k127_3998999_17 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.000000000000000000000000000000000000003143 152.0
PYH3_k127_3998999_18 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000000000004134 132.0
PYH3_k127_3998999_2 Sigma-54 interaction domain K15836 - - 3.69e-202 651.0
PYH3_k127_3998999_21 Methyltransferase domain - - - 0.0000000000000000001478 94.0
PYH3_k127_3998999_22 Methyltransferase domain - - - 0.00000004666 56.0
PYH3_k127_3998999_23 Ketosteroid isomerase-related protein - - - 0.000000214 55.0
PYH3_k127_3998999_24 Methyltransferase domain - - - 0.0003345 45.0
PYH3_k127_3998999_3 Evidence 2b Function of strongly homologous gene K18139 - - 1.035e-201 638.0
PYH3_k127_3998999_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002118 485.0
PYH3_k127_3998999_5 Pirin K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 413.0
PYH3_k127_3998999_6 electron transfer activity K03616 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 410.0
PYH3_k127_3998999_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009497 354.0
PYH3_k127_3998999_8 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K00567,K01247 - 2.1.1.63,3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006875 329.0
PYH3_k127_3998999_9 catechol 2,3-dioxygenase activity K07104 - 1.13.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004728 269.0
PYH3_k127_4046894_0 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 360.0
PYH3_k127_4046894_1 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 293.0
PYH3_k127_4046894_2 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007412 289.0
PYH3_k127_4046894_3 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000005543 207.0
PYH3_k127_4046894_4 response regulator K02282 - - 0.0000000000000000000000000008804 118.0
PYH3_k127_4046894_5 Dienelactone hydrolase family - - - 0.00000008406 56.0
PYH3_k127_4046894_6 His Kinase A (phosphoacceptor) domain - - - 0.00002085 55.0
PYH3_k127_4056069_0 His Kinase A (phosphoacceptor) domain - - - 0.0 1531.0
PYH3_k127_4056069_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 8.273e-280 867.0
PYH3_k127_4056069_2 Arginyl tRNA synthetase N terminal dom K01887 - 6.1.1.19 3.215e-209 657.0
PYH3_k127_4056069_3 phosphorelay signal transduction system - - - 6.165e-207 659.0
PYH3_k127_4056069_4 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 562.0
PYH3_k127_4056069_5 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 484.0
PYH3_k127_4056069_6 Preprotein translocase subunit K03210 - - 0.000000000000000000000000000000000006985 139.0
PYH3_k127_406455_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002558 396.0
PYH3_k127_406455_1 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 361.0
PYH3_k127_406455_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000004055 190.0
PYH3_k127_406455_4 inositol monophosphate 1-phosphatase activity K01092 - 3.1.3.25 0.00000000000000000000000000000000000000005136 159.0
PYH3_k127_409977_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 9.717e-273 859.0
PYH3_k127_409977_1 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 447.0
PYH3_k127_409977_10 Cytochrome c K00406 - - 0.0000000000000009873 82.0
PYH3_k127_409977_12 Helix-turn-helix XRE-family like proteins K21498 - - 0.0002207 45.0
PYH3_k127_409977_2 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002078 274.0
PYH3_k127_409977_3 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000003368 231.0
PYH3_k127_409977_5 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000000000000000000000000000000000000008403 209.0
PYH3_k127_409977_6 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.00000000000000000000000000000000000000000000000000008123 188.0
PYH3_k127_409977_7 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000000000000000000000000000000000000006228 183.0
PYH3_k127_409977_8 Cytochrome c K02305,K17223 - - 0.00000000000000000000000000001344 124.0
PYH3_k127_409977_9 Phosphoribosyl transferase domain - - - 0.0000000000000000000000001704 106.0
PYH3_k127_4102172_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 5.445e-320 985.0
PYH3_k127_4102172_1 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 437.0
PYH3_k127_4102172_2 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000148 266.0
PYH3_k127_4102172_3 bacterial (prokaryotic) histone like domain K05788 - - 0.000000000000000000000000000000000000000000000003782 175.0
PYH3_k127_41033_0 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000000000000000000000000000000000000000000000452 206.0
PYH3_k127_41033_1 PFAM multiple antibiotic resistance (MarC)-related protein K05595 - - 0.000000000000000000000000000000000000000000000000001093 190.0
PYH3_k127_41033_2 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000001385 179.0
PYH3_k127_41033_4 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000001 136.0
PYH3_k127_41033_5 hydroperoxide reductase activity - - - 0.000000000000000000000000000002124 136.0
PYH3_k127_41033_7 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00003588 48.0
PYH3_k127_4112798_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 591.0
PYH3_k127_4112798_1 mannose-ethanolamine phosphotransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 460.0
PYH3_k127_4112798_2 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 462.0
PYH3_k127_4112798_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 363.0
PYH3_k127_4130680_0 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003705 600.0
PYH3_k127_4130680_1 methyltransferase K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003873 581.0
PYH3_k127_4130680_2 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 544.0
PYH3_k127_4146592_0 alpha-ribazole phosphatase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0 1159.0
PYH3_k127_4146592_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 2.326e-220 694.0
PYH3_k127_4146592_2 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 297.0
PYH3_k127_4146592_4 (Barnase) inhibitor - - - 0.00000000000000000000000000000000000000000001301 168.0
PYH3_k127_4146592_5 endoribonuclease activity K03628,K15125 GO:0005575,GO:0005576 - 0.000000000000000000000000001069 117.0
PYH3_k127_4153171_0 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 408.0
PYH3_k127_4153171_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01665 GO:0000162,GO:0003674,GO:0003824,GO:0004049,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005950,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0016829,GO:0016830,GO:0016833,GO:0018130,GO:0019438,GO:0019752,GO:0032991,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0046820,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 2.6.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 385.0
PYH3_k127_4153171_2 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.000000000000000000000000000006302 121.0
PYH3_k127_415605_0 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 607.0
PYH3_k127_415605_1 Cell cycle protein K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001788 531.0
PYH3_k127_415605_2 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 416.0
PYH3_k127_415605_3 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000003729 98.0
PYH3_k127_4157391_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001442 567.0
PYH3_k127_4157391_1 proline dipeptidase activity K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002693 552.0
PYH3_k127_4157391_2 Peptidase C26 K07010 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007275 317.0
PYH3_k127_4157391_3 protein secretion K03116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 316.0
PYH3_k127_4157391_4 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001173 268.0
PYH3_k127_4157391_5 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000000000000000000002835 216.0
PYH3_k127_4157391_8 PBS lyase HEAT-like repeat - - - 0.000000000004599 76.0
PYH3_k127_4166158_0 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 572.0
PYH3_k127_4166158_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007199 559.0
PYH3_k127_4166158_2 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000002063 194.0
PYH3_k127_4166158_3 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000002306 104.0
PYH3_k127_4220691_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 551.0
PYH3_k127_4220691_1 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008733 539.0
PYH3_k127_4277609_0 efflux transmembrane transporter activity K03287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 479.0
PYH3_k127_4277609_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007833 274.0
PYH3_k127_4277609_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993,K16922 - - 0.000000000000000000000000000000000000000000000000000000000000000000001046 246.0
PYH3_k127_4300057_0 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001723 228.0
PYH3_k127_4300057_1 positive regulation of type IV pilus biogenesis K07343 - - 0.00000000000000000000000000000001352 130.0
PYH3_k127_4376510_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 3.46e-283 897.0
PYH3_k127_4376510_1 amino acid - - - 0.00000000000000000000000000000289 124.0
PYH3_k127_45068_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 5.049e-277 856.0
PYH3_k127_45068_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 1.032e-200 633.0
PYH3_k127_45068_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 1.501e-195 617.0
PYH3_k127_45068_3 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000001849 265.0
PYH3_k127_45068_4 Telomere recombination K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000001366 210.0
PYH3_k127_45068_5 Putative regulatory protein - - - 0.0000000000000000000000000007615 117.0
PYH3_k127_4525194_0 Animal haem peroxidase - - - 0.0 1403.0
PYH3_k127_4525194_1 PFAM Integrase catalytic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001659 275.0
PYH3_k127_4525194_2 PIN domain - - - 0.000000000000000000000000001779 117.0
PYH3_k127_4525194_3 toxin-antitoxin pair type II binding - - - 0.00000000000000000000007774 99.0
PYH3_k127_4525194_4 transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000009301 63.0
PYH3_k127_4746522_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000196 447.0
PYH3_k127_4746522_1 dTDP biosynthetic process K00560,K00943,K01585 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0004798,GO:0005488,GO:0005515,GO:0005524,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009129,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009161,GO:0009165,GO:0009173,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009218,GO:0009219,GO:0009221,GO:0009259,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0017076,GO:0018130,GO:0019001,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0019693,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046044,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046872,GO:0046940,GO:0046983,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.1.1.45,2.7.4.9,4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004917 280.0
PYH3_k127_4746522_2 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000002545 112.0
PYH3_k127_486886_0 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 9.225e-194 607.0
PYH3_k127_486886_1 protein complex oligomerization - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008568 531.0
PYH3_k127_486886_2 peptidase K02557,K21471 - - 0.0000000000000000000000000000000000000000000002868 178.0
PYH3_k127_486886_3 4 iron, 4 sulfur cluster binding K02573 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000001769 157.0
PYH3_k127_486886_4 YHYH protein - - - 0.00000000000000000000000000000000000001326 149.0
PYH3_k127_486886_5 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000003088 69.0
PYH3_k127_486886_6 COG1943 Transposase and inactivated derivatives K07491 - - 0.00000003092 56.0
PYH3_k127_4930454_0 phosphorelay sensor kinase activity K02668 - 2.7.13.3 4.376e-249 780.0
PYH3_k127_4930454_1 Type II secretion system (T2SS), protein F K02455,K02653 - - 4.034e-204 640.0
PYH3_k127_4930454_10 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000004411 147.0
PYH3_k127_4930454_11 YGGT family K02221 - - 0.00000000000000000000000000000000000006205 148.0
PYH3_k127_4930454_12 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000001996 53.0
PYH3_k127_4930454_13 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0001562 45.0
PYH3_k127_4930454_2 response regulator K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006676 507.0
PYH3_k127_4930454_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 481.0
PYH3_k127_4930454_4 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 426.0
PYH3_k127_4930454_5 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 331.0
PYH3_k127_4930454_6 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 286.0
PYH3_k127_4930454_7 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000000000000000000000004522 222.0
PYH3_k127_4930454_8 DivIVA protein K04074 - - 0.0000000000000000000000000000000000000000000000000000000007039 205.0
PYH3_k127_4936694_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 519.0
PYH3_k127_4936694_1 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 334.0
PYH3_k127_4936694_2 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003134 280.0
PYH3_k127_4936694_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000002963 240.0
PYH3_k127_4936694_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.000000000000000000000000271 106.0
PYH3_k127_4937128_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1663.0
PYH3_k127_4937128_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 489.0
PYH3_k127_4937128_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.0000000000000000000000000000000000000000000000000000000003747 209.0
PYH3_k127_4937128_11 peptidyl-lysine modification to peptidyl-hypusine - - - 0.0000000000000000000000000000000000000000000000000000000004567 202.0
PYH3_k127_4937128_12 SprT-like family K02742 - - 0.000000000000000000000000000000000000000000000000000000001961 209.0
PYH3_k127_4937128_13 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000000000000000000000000000000003489 187.0
PYH3_k127_4937128_14 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.000000000000000000000000000000000000000000000007378 178.0
PYH3_k127_4937128_2 SurA N-terminal domain K03771 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 356.0
PYH3_k127_4937128_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 348.0
PYH3_k127_4937128_4 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 330.0
PYH3_k127_4937128_5 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
PYH3_k127_4937128_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 321.0
PYH3_k127_4937128_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009554 301.0
PYH3_k127_4937128_8 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose - - - 0.0000000000000000000000000000000000000000000000000000000000000000001016 234.0
PYH3_k127_4937128_9 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000003022 216.0
PYH3_k127_4968673_0 Glycogen debranching enzyme - - - 1.847e-267 826.0
PYH3_k127_4968673_1 alpha amylase, catalytic region - - - 2.385e-249 777.0
PYH3_k127_4968673_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 540.0
PYH3_k127_4968673_3 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000000000002667 156.0
PYH3_k127_4968673_4 alpha amylase, catalytic region - - - 0.0003504 44.0
PYH3_k127_4994044_0 chlorophyll binding K03640 - - 0.0000000000000000000000000000000000000000000000000000000000000000000101 242.0
PYH3_k127_4994044_1 PFAM nuclease (SNase domain protein) - - - 0.0000000000000000000000000000785 120.0
PYH3_k127_4994044_2 PFAM YcfA-like protein - - - 0.00000000002475 65.0
PYH3_k127_4994366_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 537.0
PYH3_k127_4994366_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 516.0
PYH3_k127_4994366_2 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003686 482.0
PYH3_k127_4994366_3 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000727 440.0
PYH3_k127_4994366_4 Rhomboid family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004207 369.0
PYH3_k127_4994366_5 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000006395 236.0
PYH3_k127_4994366_6 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000000000003071 188.0
PYH3_k127_5001539_0 helicase activity - - - 0.0 1285.0
PYH3_k127_5001539_1 Uncharacterized protein family, UPF0114 K03535 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005257 296.0
PYH3_k127_5001539_2 Product type r regulator - - - 0.000000000000000000000000000000000000000000000000000000008345 205.0
PYH3_k127_5001539_3 SMART PAS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000002014 209.0
PYH3_k127_5001539_4 - - - - 0.0000000000000000000000000000000000000000000000000003371 199.0
PYH3_k127_5001539_5 Protein conserved in bacteria K09922 - - 0.0000000000000000000000000000007911 121.0
PYH3_k127_5001539_6 Histidine kinase K07682 GO:0000166,GO:0000287,GO:0001666,GO:0003032,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0005488,GO:0005509,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0009593,GO:0009628,GO:0009987,GO:0016020,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0017076,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0019825,GO:0019826,GO:0020037,GO:0030312,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0036293,GO:0040007,GO:0042165,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0046872,GO:0046906,GO:0048037,GO:0050896,GO:0051606,GO:0051775,GO:0051776,GO:0070025,GO:0070026,GO:0070482,GO:0070483,GO:0071704,GO:0071944,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564 2.7.13.3 0.00000000000000000000001151 108.0
PYH3_k127_5001539_7 cheY-homologous receiver domain - - - 0.000000001312 64.0
PYH3_k127_5034249_0 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 3.036e-246 766.0
PYH3_k127_5034249_1 phosphorelay sensor kinase activity K02038,K02282,K07018,K07315 - 3.1.3.3 2.363e-205 689.0
PYH3_k127_5034249_3 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 393.0
PYH3_k127_5034249_5 RNase_H superfamily K07502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 299.0
PYH3_k127_5034249_6 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000002877 199.0
PYH3_k127_5043271_0 Tetratricopeptide repeat - - - 5.467e-232 724.0
PYH3_k127_5043271_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 543.0
PYH3_k127_5043271_2 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000000000000000000000000000000000000000000000002754 256.0
PYH3_k127_5043271_3 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000000000000000000834 161.0
PYH3_k127_5043271_4 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000001864 121.0
PYH3_k127_5043271_5 toxin-antitoxin pair type II binding - - - 0.00000000000000003702 84.0
PYH3_k127_5043271_6 LemA family K03744 - - 0.00000000000001168 78.0
PYH3_k127_5043271_7 E3 Ubiquitin ligase - - - 0.0000000000002393 82.0
PYH3_k127_5043271_8 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.0000008455 51.0
PYH3_k127_505521_0 ATPase, AAA K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000678 447.0
PYH3_k127_505521_1 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 325.0
PYH3_k127_505521_2 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006792 327.0
PYH3_k127_505521_3 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000000000003158 209.0
PYH3_k127_505521_4 Belongs to the HesB IscA family K15724 - - 0.000000000000000000000000000000000000000000000000000000003467 201.0
PYH3_k127_505521_5 synthase K01737 - 4.1.2.50,4.2.3.12 0.00000000000000000000000000000000000000000000000000000001008 201.0
PYH3_k127_505521_7 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.00000000000000000000000001888 109.0
PYH3_k127_50617_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 398.0
PYH3_k127_50617_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007662 343.0
PYH3_k127_50617_2 Phosphoserine phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 287.0
PYH3_k127_5064278_0 AAA domain - - - 0.0 1058.0
PYH3_k127_5064278_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002547 535.0
PYH3_k127_5064278_2 regulation of translation K03704,K05809 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000079 257.0
PYH3_k127_5064278_3 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.000000000000000000000000000000000000000000000000000000000000000000021 236.0
PYH3_k127_507221_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 1.588e-232 728.0
PYH3_k127_507221_1 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003861 387.0
PYH3_k127_507221_2 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 360.0
PYH3_k127_507221_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009014 316.0
PYH3_k127_507221_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001088 280.0
PYH3_k127_507221_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000001191 256.0
PYH3_k127_5081927_0 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 549.0
PYH3_k127_5081927_1 PFAM DNA photolyase, FAD-binding K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009639 350.0
PYH3_k127_5081927_2 sirohydrochlorin cobaltochelatase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 297.0
PYH3_k127_5081927_3 - - - - 0.000000000000000000000000000000000000000000000000001156 184.0
PYH3_k127_5081927_4 PFAM Ammonia monooxygenase particulate methane monooxygenase, subunit C K10946 - - 0.000000000000000000000000000000000000003825 147.0
PYH3_k127_5159804_0 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 385.0
PYH3_k127_5159804_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000002181 181.0
PYH3_k127_5173378_0 PFAM Mammalian cell entry related domain protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 561.0
PYH3_k127_5173378_1 Paraquat-inducible protein A K03808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008803 262.0
PYH3_k127_5173378_2 ABC-type transport auxiliary lipoprotein component - - - 0.0000000000000000000000000000000000000002032 157.0
PYH3_k127_5173378_3 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000000000000000000000000000003881 134.0
PYH3_k127_5173378_4 PFAM Paraquat-inducible protein A K03808 - - 0.0000000000000000009777 87.0
PYH3_k127_5177798_0 TIGRFAM DNA polymerase III, alpha subunit K02337 - 2.7.7.7 0.0 1068.0
PYH3_k127_5177798_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 527.0
PYH3_k127_5192884_0 PFAM type II secretion system protein E K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 330.0
PYH3_k127_5192884_1 COGs COG3485 Protocatechuate 3 4-dioxygenase beta subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002036 285.0
PYH3_k127_5192884_2 - - - - 0.0000000000000000000000009174 104.0
PYH3_k127_5192884_4 Outer membrane lipoprotein Slp family K07285 - - 0.000008623 55.0
PYH3_k127_5218304_0 metallopeptidase activity K03568 - - 1.738e-258 803.0
PYH3_k127_5218304_1 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004389 617.0
PYH3_k127_5218304_2 metallopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 593.0
PYH3_k127_5218304_3 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 287.0
PYH3_k127_5218304_4 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000005112 177.0
PYH3_k127_5218304_5 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.0000000000000000000000000000000000002054 143.0
PYH3_k127_5218304_6 Transglycosylase SLT domain - - - 0.00000000000000000000000001047 115.0
PYH3_k127_521986_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 8.394e-263 815.0
PYH3_k127_521986_1 TIGRFAM formate dehydrogenase, alpha subunit, archaeal-type K00123 - 1.17.1.9 3.419e-249 798.0
PYH3_k127_521986_2 fructose-bisphosphate aldolase activity K01622 - 3.1.3.11,4.1.2.13 4.315e-228 709.0
PYH3_k127_521986_4 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000004616 254.0
PYH3_k127_521986_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000003871 178.0
PYH3_k127_521986_6 formate transmembrane transporter activity K02598,K06212,K21993 - - 0.000000000000000000000000000000000005233 141.0
PYH3_k127_521986_7 Belongs to the universal stress protein A family - - - 0.00000000000000007795 81.0
PYH3_k127_5275132_0 Trypsin K04771 - 3.4.21.107 1e-233 733.0
PYH3_k127_5275132_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000308 610.0
PYH3_k127_5275132_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 509.0
PYH3_k127_5275132_3 Probable molybdopterin binding domain K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 375.0
PYH3_k127_5275132_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 289.0
PYH3_k127_5275132_6 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000005818 220.0
PYH3_k127_5299201_0 Aminotransferase class I and II K14261 - - 8.179e-235 729.0
PYH3_k127_5299201_1 Homoserine dehydrogenase K00003 - 1.1.1.3 6.89e-223 696.0
PYH3_k127_5299201_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 592.0
PYH3_k127_5299201_3 Metalloenzyme superfamily K15635 - 5.4.2.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002852 394.0
PYH3_k127_5299201_4 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000002177 180.0
PYH3_k127_5308822_0 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006872 469.0
PYH3_k127_5308822_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009412 394.0
PYH3_k127_5308822_2 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH3_k127_5308822_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000369 237.0
PYH3_k127_5367610_0 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 368.0
PYH3_k127_5367610_2 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
PYH3_k127_5367610_3 photosynthesis K02453,K02660 - - 0.00000000000000000000000000000000000000000000000000000001367 205.0
PYH3_k127_5382765_0 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 359.0
PYH3_k127_5382765_1 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 348.0
PYH3_k127_5382765_10 PFAM Glycosyl transferase family 2 - - - 0.0000103 53.0
PYH3_k127_5382765_11 Protein of unknown function (DUF2441) - - - 0.0006279 48.0
PYH3_k127_5382765_2 Protein of unknown function (DUF1810) - - - 0.000000000000000000000000000000000000000000000008761 177.0
PYH3_k127_5382765_3 Aminoacyl-tRNA editing domain K19055 - - 0.0000000000000000000000000000000000000008231 156.0
PYH3_k127_5382765_4 PFAM response regulator receiver - - - 0.0000000000000000000000000008708 116.0
PYH3_k127_5382765_5 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000004885 109.0
PYH3_k127_5382765_6 PFAM nuclease (SNase domain protein) - - - 0.00000000000007929 75.0
PYH3_k127_5382765_7 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.000000000000112 71.0
PYH3_k127_5382765_9 - - - - 0.000000387 56.0
PYH3_k127_545033_0 response to oxidative stress K04063 - - 0.000000000000000000000000000000000000000000000000000000000000000000008319 235.0
PYH3_k127_545033_1 - - - - 0.0000000000000000000000000000000000000000000000000000000001477 209.0
PYH3_k127_545033_2 Cytochrome c K12263 - - 0.00000000000000000000000000003506 120.0
PYH3_k127_545033_3 Cytochrome c K12263 - - 0.0000000000209 65.0
PYH3_k127_546438_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1658.0
PYH3_k127_546438_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 567.0
PYH3_k127_546438_4 Cytochrome P450 - - - 0.00000003734 60.0
PYH3_k127_5556767_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008914,GO:0016740,GO:0016746,GO:0016755,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0044424,GO:0044464,GO:0071704,GO:0140096,GO:1901564 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002667 273.0
PYH3_k127_5556767_2 AntiSigma factor - - - 0.0000000000000000000000004693 107.0
PYH3_k127_5556767_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000004453 61.0
PYH3_k127_5601916_0 Type II/IV secretion system protein K02454,K02652 - - 8.641e-228 719.0
PYH3_k127_5601916_1 PFAM Nickel transport complex, NikM subunit, transmembrane - - - 0.0007747 43.0
PYH3_k127_5617662_0 transcription factor binding K02584,K12146,K15836 - - 2.993e-278 874.0
PYH3_k127_5617662_1 efflux transmembrane transporter activity K02004 - - 1.186e-208 655.0
PYH3_k127_5617662_2 actin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 513.0
PYH3_k127_5617662_4 Evidence 2b Function of strongly homologous gene K02003,K09810,K09814 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 372.0
PYH3_k127_5617662_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K01993 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 307.0
PYH3_k127_5675450_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 5.934e-297 913.0
PYH3_k127_5675450_1 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003256 248.0
PYH3_k127_5675450_2 cysteine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000007791 215.0
PYH3_k127_5675450_3 - - - - 0.000000000000000000000000000000000000000000001831 168.0
PYH3_k127_5675450_4 Conserved region in glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.000000000000008832 74.0
PYH3_k127_5767489_0 Flagellar Motor Protein K02557 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 410.0
PYH3_k127_5767489_1 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 350.0
PYH3_k127_5767489_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 344.0
PYH3_k127_577755_0 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 1.769e-240 753.0
PYH3_k127_577755_1 Uncharacterized conserved protein (DUF2294) - - - 0.00000000000000000000000000000000000761 137.0
PYH3_k127_5904538_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 6.718e-215 678.0
PYH3_k127_5904538_1 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009184 540.0
PYH3_k127_5904538_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 435.0
PYH3_k127_5904538_3 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003663 383.0
PYH3_k127_5904538_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000005459 254.0
PYH3_k127_5904538_5 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000002156 216.0
PYH3_k127_5904538_6 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000004908 172.0
PYH3_k127_5907615_0 lipopolysaccharide transport K22110 - - 0.0 1466.0
PYH3_k127_5907615_1 Cytochrome c mono- and diheme variants - - - 0.00000000000000000000000000000000000000000000000000000000005328 211.0
PYH3_k127_5907615_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.00000000000000000004354 94.0
PYH3_k127_5907615_3 - - - - 0.0000000007609 63.0
PYH3_k127_5907615_4 Sigma-54 interaction domain - - - 0.0000009448 51.0
PYH3_k127_5907615_5 PFAM nuclease (SNase domain protein) - - - 0.00003569 48.0
PYH3_k127_5907615_6 SMP-30/Gluconolaconase/LRE-like region K01053 - 3.1.1.17 0.0002677 46.0
PYH3_k127_6023514_1 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003626 450.0
PYH3_k127_6023514_2 Glycine-zipper domain - - - 0.000000000000000000000000000000000000000000000000001034 186.0
PYH3_k127_6023514_3 phosphorelay signal transduction system K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000001166 160.0
PYH3_k127_6023514_4 - - - - 0.000000000000000001399 92.0
PYH3_k127_6107961_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 431.0
PYH3_k127_6107961_1 thiolester hydrolase activity K06889,K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 318.0
PYH3_k127_6107961_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 248.0
PYH3_k127_6107961_4 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.00000000000000000002038 90.0
PYH3_k127_6138968_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000001462 183.0
PYH3_k127_6138968_1 Transposase IS116/IS110/IS902 family - - - 0.0000000000000004383 90.0
PYH3_k127_6142198_0 Molydopterin dinucleotide binding domain K00302,K10814 - 1.4.99.5,1.5.3.1 0.0 1174.0
PYH3_k127_6142198_1 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 0.0 1060.0
PYH3_k127_6142198_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 8.117e-264 819.0
PYH3_k127_6142198_3 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342,K05575 - 1.6.5.3 4.312e-212 666.0
PYH3_k127_6142198_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004052 369.0
PYH3_k127_6142198_5 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000004624 249.0
PYH3_k127_6142198_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000001743 167.0
PYH3_k127_6152398_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1118.0
PYH3_k127_6165433_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 2.092e-235 734.0
PYH3_k127_6165433_1 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
PYH3_k127_6165433_10 Domain of unknown function (DUF4321) - - - 0.000000000000000000000000000000004346 130.0
PYH3_k127_6165433_2 ABC transporter K09812 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 332.0
PYH3_k127_6165433_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000168 288.0
PYH3_k127_6165433_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001156 285.0
PYH3_k127_6165433_5 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000003405 203.0
PYH3_k127_6165433_6 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000003226 191.0
PYH3_k127_6165433_7 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000000006197 171.0
PYH3_k127_6165433_8 Uncharacterised protein family UPF0102 K07460 - - 0.000000000000000000000000000000000000000000003543 169.0
PYH3_k127_6165433_9 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000001703 160.0
PYH3_k127_6171321_0 polyphosphate kinase activity K22468 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 560.0
PYH3_k127_6171321_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 332.0
PYH3_k127_6171321_10 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000008515 75.0
PYH3_k127_6171321_11 DnaK suppressor protein - - - 0.0000000001861 66.0
PYH3_k127_6171321_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000009347 228.0
PYH3_k127_6171321_3 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000004546 195.0
PYH3_k127_6171321_5 ATP-independent chaperone mediated protein folding - - - 0.00000000000000000000000000000000000000000000000006165 184.0
PYH3_k127_6171321_6 IMP dehydrogenase activity K09137 - - 0.00000000000000000000000000000000000000002287 157.0
PYH3_k127_6171321_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000003874 123.0
PYH3_k127_6171321_8 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000009234 99.0
PYH3_k127_6171321_9 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE K06039,K07235 - - 0.000000000000000000009717 91.0
PYH3_k127_6186530_0 Pup-ligase protein K20814 - 3.5.1.119 1.789e-275 853.0
PYH3_k127_6186530_1 Pup-ligase protein K13571 - 6.3.1.19 1.473e-240 753.0
PYH3_k127_6186530_2 Proteasomal ATPase OB/ID domain K13527 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 438.0
PYH3_k127_6186530_3 Proteasome subunit K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 437.0
PYH3_k127_6186530_4 Proteasome subunit K03432 - 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 344.0
PYH3_k127_6186530_5 poly(3-hydroxybutyrate) depolymerase activity K07019 GO:0003674,GO:0003824,GO:0006629,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016788,GO:0044237,GO:0044238,GO:0044255,GO:0071704 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004096 260.0
PYH3_k127_6186530_6 May function as a protein modifier covalently attached to lysine residues of substrate proteins. This may serve to target the modified proteins for degradation by proteasomes - - - 0.000000000000000000000002342 107.0
PYH3_k127_6190187_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 6.775e-218 677.0
PYH3_k127_6190187_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 465.0
PYH3_k127_6190187_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.0000000000000000000000000000000000000000000000000000000000000000009813 229.0
PYH3_k127_6217050_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 523.0
PYH3_k127_6217050_1 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002278 515.0
PYH3_k127_6217050_2 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003862 353.0
PYH3_k127_6217050_3 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 297.0
PYH3_k127_6217050_5 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000003213 233.0
PYH3_k127_6217050_6 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000001663 209.0
PYH3_k127_6217050_7 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000006327 190.0
PYH3_k127_623077_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1040.0
PYH3_k127_623077_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 2.249e-257 801.0
PYH3_k127_623077_2 B3/4 domain K01890 - 6.1.1.20 8.728e-246 770.0
PYH3_k127_623077_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004396 341.0
PYH3_k127_623077_4 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005209 287.0
PYH3_k127_623077_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000426 196.0
PYH3_k127_623077_6 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000002829 168.0
PYH3_k127_623077_7 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000002613 80.0
PYH3_k127_6267373_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 346.0
PYH3_k127_6267373_2 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000824 316.0
PYH3_k127_6267373_4 Iron-sulfur cluster-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009295 242.0
PYH3_k127_6267373_5 zinc ion binding - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000001033 237.0
PYH3_k127_6267373_6 Iron-binding zinc finger CDGSH type - - - 0.0000000000000000000000000001781 116.0
PYH3_k127_6290760_0 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 1.756e-206 656.0
PYH3_k127_6290760_1 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 369.0
PYH3_k127_6290760_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000001646 212.0
PYH3_k127_6292950_0 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000226 271.0
PYH3_k127_6292950_1 histidine kinase A domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003678 242.0
PYH3_k127_6292950_2 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.0000000000000000000000000000000000000000000000000000000241 205.0
PYH3_k127_6310033_0 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009534 582.0
PYH3_k127_6310033_1 Signal transducing histidine kinase, homodimeric domain K02487,K03407,K06596 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009584 489.0
PYH3_k127_6310033_2 nuclear chromosome segregation K02666,K03497,K19622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005642 278.0
PYH3_k127_6310033_3 PFAM metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000002159 185.0
PYH3_k127_6310033_5 chemotaxis K02659,K03408,K03415,K11524 - - 0.000000000000000000000000000007584 124.0
PYH3_k127_6323819_0 phosphorelay signal transduction system - - - 1.105e-203 642.0
PYH3_k127_6323819_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 509.0
PYH3_k127_6323819_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 375.0
PYH3_k127_6323819_3 similarity to OMNI NTL01RS2573 K07485 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 339.0
PYH3_k127_6323819_4 - - - - 0.000000000000000000000000000001057 125.0
PYH3_k127_6323819_5 AMP binding - - - 0.0000000000000000000000000005486 115.0
PYH3_k127_6323819_6 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000005853 113.0
PYH3_k127_6323819_7 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000001106 102.0
PYH3_k127_6323819_8 mRNA binding K07339 - - 0.0000000001219 64.0
PYH3_k127_6335863_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 6.185e-317 981.0
PYH3_k127_6335863_1 Rieske (2fe-2S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002795 549.0
PYH3_k127_6335863_2 Male sterility protein K08679 - 5.1.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 406.0
PYH3_k127_6335863_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 316.0
PYH3_k127_6335863_4 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000305 289.0
PYH3_k127_6335863_6 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000006625 149.0
PYH3_k127_6348420_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 344.0
PYH3_k127_6348420_1 Adenosine specific kinase K09129 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001884 251.0
PYH3_k127_6348420_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000000000000000003137 228.0
PYH3_k127_6348420_3 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000000001239 179.0
PYH3_k127_6348420_4 DNA polymerase X family K02347 - - 0.0000000000000000000002126 96.0
PYH3_k127_6348420_5 Dodecin K09165 - - 0.000000000000000000008799 93.0
PYH3_k127_6348420_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000009344 54.0
PYH3_k127_6348420_7 THUMP - - - 0.0001125 48.0
PYH3_k127_6381056_0 Ftsk_gamma K03466 - - 6.606e-204 646.0
PYH3_k127_6387672_0 spermidine synthase activity K00797 - 2.5.1.16 1.469e-219 690.0
PYH3_k127_6392276_0 HlyD family secretion protein K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 591.0
PYH3_k127_6392276_1 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 583.0
PYH3_k127_6392276_2 Belongs to the TPP enzyme family K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 348.0
PYH3_k127_6392276_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003527 278.0
PYH3_k127_6392276_6 AcrB/AcrD/AcrF family - - - 0.000000000000000000000000000000000000000000000000000000006793 199.0
PYH3_k127_6392276_7 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000002714 175.0
PYH3_k127_6392276_8 Nucleotidyl transferase - - - 0.00000000000000000000000001705 110.0
PYH3_k127_6396762_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 2.856e-254 823.0
PYH3_k127_6396762_1 self proteolysis - - - 0.0000000000000000217 89.0
PYH3_k127_6479101_0 carboxylic acid catabolic process K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0016855,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 513.0
PYH3_k127_6479101_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 434.0
PYH3_k127_6479101_3 - - - - 0.00000000000000000000000000000000000000000000000000000000001147 222.0
PYH3_k127_6479101_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000148 185.0
PYH3_k127_6479101_5 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0000000000000000000000000008966 114.0
PYH3_k127_6489208_0 NHL repeat - - - 7.897e-240 744.0
PYH3_k127_6489208_1 denitrification pathway - - - 3.803e-222 694.0
PYH3_k127_6489208_2 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006894 454.0
PYH3_k127_6489208_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000005847 61.0
PYH3_k127_6489208_5 denitrification pathway - - - 0.000001952 52.0
PYH3_k127_6509512_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1091.0
PYH3_k127_6509512_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 356.0
PYH3_k127_6509512_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000000000000000000000009806 177.0
PYH3_k127_6509512_3 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000444 153.0
PYH3_k127_6509512_4 Protein conserved in bacteria K09764 - - 0.00000000000000000000000000000000001392 137.0
PYH3_k127_6509512_5 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000001119 80.0
PYH3_k127_6532774_0 AcrB/AcrD/AcrF family K07787 - - 0.0 1520.0
PYH3_k127_6532774_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001965 376.0
PYH3_k127_6532774_2 Metallo-beta-lactamase superfamily K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005977 368.0
PYH3_k127_6532774_3 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 322.0
PYH3_k127_6532774_4 Transposase, Mutator family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001722 273.0
PYH3_k127_6532774_5 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000001293 77.0
PYH3_k127_6532774_6 - - - - 0.000001796 54.0
PYH3_k127_659872_0 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1033.0
PYH3_k127_659872_4 - - - - 0.0004566 43.0
PYH3_k127_6620552_0 Homeodomain-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001177 258.0
PYH3_k127_6620552_1 AAA domain - - - 0.000000000000000000000000000000000000000000000001248 184.0
PYH3_k127_6742442_0 von Willebrand factor (vWF) type A domain K02448 - - 2.108e-232 741.0
PYH3_k127_6742442_1 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000008786 250.0
PYH3_k127_6742442_2 Winged helix-turn-helix DNA-binding - - - 0.00000002064 58.0
PYH3_k127_6742442_3 - - - - 0.00000878 56.0
PYH3_k127_6769461_0 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 344.0
PYH3_k127_6769461_1 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002294 233.0
PYH3_k127_6769461_2 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.000000000000000000000000000000000000000000000000000000000000000000167 244.0
PYH3_k127_6769461_3 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000003539 113.0
PYH3_k127_6812903_0 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003683 261.0
PYH3_k127_6812903_1 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000000000000295 199.0
PYH3_k127_6812903_2 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.00000000000000000000000000000000000000000297 159.0
PYH3_k127_6824680_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 467.0
PYH3_k127_6824680_1 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004304 458.0
PYH3_k127_6824680_2 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009192 378.0
PYH3_k127_6877380_0 FtsX-like permease family K02004 - - 7.398e-272 852.0
PYH3_k127_6877380_1 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 355.0
PYH3_k127_6877380_2 Peptidase family M1 domain K08776 - - 0.00000000000000000000000000000001848 127.0
PYH3_k127_6963513_0 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 422.0
PYH3_k127_6963513_1 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 415.0
PYH3_k127_6963513_3 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0000000000000000000000000000000000000000000002653 168.0
PYH3_k127_6963513_6 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.000000000002877 68.0
PYH3_k127_6989008_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 377.0
PYH3_k127_6989008_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 325.0
PYH3_k127_6989008_2 TPM domain K06872 - - 0.00000000000000000000000000000000000000000000000000000000000000003466 233.0
PYH3_k127_6989008_3 Membrane K08988 - - 0.00000000000000000000000000000000000000000000000000000006127 202.0
PYH3_k127_7055241_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1161.0
PYH3_k127_7055241_1 PFAM SNF2-related protein - - - 2.958e-239 782.0
PYH3_k127_7055241_2 DHH family K07462 - - 3.548e-225 708.0
PYH3_k127_7055241_3 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001026 263.0
PYH3_k127_7055241_4 metalloendopeptidase activity K08602 - - 0.00000000000000000000000000000000000000000000000000000000004952 206.0
PYH3_k127_7055241_5 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000000002241 188.0
PYH3_k127_7055241_7 2 iron, 2 sulfur cluster binding K02192 GO:0003674,GO:0005488,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.000000000000000005855 85.0
PYH3_k127_7055241_8 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.0001668 44.0
PYH3_k127_7276263_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1399.0
PYH3_k127_7276263_1 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 4.312e-232 729.0
PYH3_k127_7276263_11 sequence-specific DNA binding - - - 0.000000000000000000000000000002832 123.0
PYH3_k127_7276263_2 Alpha/beta hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 393.0
PYH3_k127_7276263_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009765 349.0
PYH3_k127_7276263_5 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002797 285.0
PYH3_k127_7276263_8 Protein of unknown function (DUF423) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000004906 158.0
PYH3_k127_7386536_0 Phosphoglycerate kinase K00927 - 2.7.2.3 8.771e-220 687.0
PYH3_k127_7386536_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002518 376.0
PYH3_k127_7386536_2 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 286.0
PYH3_k127_7386536_3 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000000000633 144.0
PYH3_k127_7392087_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 447.0
PYH3_k127_7392087_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 437.0
PYH3_k127_7392087_2 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000003121 224.0
PYH3_k127_7392087_4 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.000000000000000000000008838 103.0
PYH3_k127_7403787_0 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 469.0
PYH3_k127_7403787_1 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005844 419.0
PYH3_k127_7403787_2 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000000000000000000000000000000000000001939 212.0
PYH3_k127_7403787_3 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000002961 189.0
PYH3_k127_7403787_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000001802 95.0
PYH3_k127_7411612_0 pyruvate decarboxylase activity K04103 - 4.1.1.74 1.205e-274 857.0
PYH3_k127_7411612_1 transferase activity, transferring glycosyl groups K13693 - 2.4.1.266 1.235e-217 681.0
PYH3_k127_7411612_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 482.0
PYH3_k127_7411612_3 Glycosyl transferase, family 2 K21349 - 2.4.1.268 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009951 370.0
PYH3_k127_7411612_4 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000001107 172.0
PYH3_k127_7448526_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 1.678e-237 738.0
PYH3_k127_7448526_2 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000007377 231.0
PYH3_k127_7448526_3 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000445 228.0
PYH3_k127_7448526_4 Histidine kinase K00060,K07777 - 1.1.1.103,2.7.13.3 0.00000000000000000000000000000000000001443 149.0
PYH3_k127_7456076_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 2.747e-222 693.0
PYH3_k127_7456076_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 391.0
PYH3_k127_7456076_2 Major Facilitator Superfamily K02575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001043 250.0
PYH3_k127_7456076_3 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000001888 231.0
PYH3_k127_7456076_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000000000000000006199 207.0
PYH3_k127_7472043_0 mismatched DNA binding K03555 - - 3.662e-209 667.0
PYH3_k127_7472043_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 438.0
PYH3_k127_7472043_2 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008741 289.0
PYH3_k127_7472043_3 Phosphate acyltransferases K01897,K05939 - 2.3.1.40,6.2.1.20,6.2.1.3 0.000000000000000000000000000000000000000000000000001809 187.0
PYH3_k127_7472043_4 MOSC domain - - - 0.00000000000000000000000000000000000000000000003164 173.0
PYH3_k127_7511136_0 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 4.92e-278 859.0
PYH3_k127_7511136_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002483 570.0
PYH3_k127_7511136_2 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 512.0
PYH3_k127_7511136_3 Carbon-nitrogen hydrolase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005211 507.0
PYH3_k127_7512212_0 RNA polymerase beta subunit external 1 domain K03043 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1612.0
PYH3_k127_7512212_1 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1241.0
PYH3_k127_7512212_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000000000000000000000000000000000000001429 197.0
PYH3_k127_7512212_11 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.0000000000000000000001866 97.0
PYH3_k127_7512212_12 P-P-bond-hydrolysis-driven protein transmembrane transporter activity K03073 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00000000000000001398 86.0
PYH3_k127_7512212_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.63e-245 759.0
PYH3_k127_7512212_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006321 460.0
PYH3_k127_7512212_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 408.0
PYH3_k127_7512212_5 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 390.0
PYH3_k127_7512212_6 Participates in transcription elongation, termination and antitermination K02601 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 325.0
PYH3_k127_7512212_7 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009302 258.0
PYH3_k127_7512212_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000004523 233.0
PYH3_k127_7512212_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000004581 219.0
PYH3_k127_7523579_0 arylsulfatase A K01130 - 3.1.6.1 7.491e-233 724.0
PYH3_k127_7523579_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 511.0
PYH3_k127_7523579_2 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.000000000000000000000000000000000000000000004354 168.0
PYH3_k127_7523579_3 - - - - 0.000000000000001047 80.0
PYH3_k127_7523579_4 Patatin-like phospholipase K07001 - - 0.000000001291 61.0
PYH3_k127_7529629_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 6.195e-319 983.0
PYH3_k127_7529629_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 8.415e-219 681.0
PYH3_k127_7529629_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 304.0
PYH3_k127_7529629_3 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 304.0
PYH3_k127_7548727_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007107 561.0
PYH3_k127_7548727_1 ABC transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004334 385.0
PYH3_k127_7548727_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 347.0
PYH3_k127_7548727_3 Protein conserved in bacteria K11719 - - 0.000000000000000000000000000000000000000000000000000000000000000000001467 240.0
PYH3_k127_7548727_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.000000000000000000000000000000000000000000000000000000000000000000001638 236.0
PYH3_k127_7548727_5 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000001264 206.0
PYH3_k127_7548727_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000002911 201.0
PYH3_k127_7548727_7 OstA-like protein K09774 - - 0.00000000000000000000000000000000000000000001653 169.0
PYH3_k127_7548727_8 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000005954 71.0
PYH3_k127_7554603_0 DDE superfamily endonuclease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 458.0
PYH3_k127_7554603_1 PFAM TrkA-C domain protein K11105 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 404.0
PYH3_k127_7554603_2 Glutathione S-transferase, N-terminal domain K07393 - 1.8.5.7 0.00000000000000000000000000000000000000000003911 162.0
PYH3_k127_7555444_0 peptidyl-tyrosine sulfation - - - 8.342e-211 703.0
PYH3_k127_7555444_1 Amidohydrolase K07045 - - 0.0000000000000000000000000179 117.0
PYH3_k127_7555444_2 Type II and III secretion system protein K02453 - - 0.00000000000000005975 92.0
PYH3_k127_7591831_0 silver ion transport K15726 - - 0.0 1379.0
PYH3_k127_7591831_1 Multicopper oxidase type 1 - - - 7.143e-261 816.0
PYH3_k127_7591831_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 432.0
PYH3_k127_7591831_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 379.0
PYH3_k127_7591831_4 AMP binding - - - 0.000000000000000000000000000753 114.0
PYH3_k127_7619586_0 Histidine kinase K07638 - 2.7.13.3 8.066e-313 980.0
PYH3_k127_7619586_1 Transglycosylase K05365,K05366 - 2.4.1.129,3.4.16.4 4.04e-255 798.0
PYH3_k127_7619586_2 Histidine kinase K03406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001303 259.0
PYH3_k127_7619586_3 Histidine kinase K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000268 228.0
PYH3_k127_7619586_4 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000000002662 182.0
PYH3_k127_7639028_0 AcrB/AcrD/AcrF family K15726 - - 4.887e-234 746.0
PYH3_k127_7639028_1 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 400.0
PYH3_k127_7643416_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 1.934e-260 808.0
PYH3_k127_7643416_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004133 574.0
PYH3_k127_7643416_2 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 413.0
PYH3_k127_7643416_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 331.0
PYH3_k127_7643416_4 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000783 264.0
PYH3_k127_7655612_0 DNA topoisomerase II activity K03167 - 5.99.1.3 0.0 1007.0
PYH3_k127_7655612_1 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 2.56e-222 691.0
PYH3_k127_7667235_0 polyribonucleotide nucleotidyltransferase activity K00962 GO:0000166,GO:0000175,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004518,GO:0004527,GO:0004532,GO:0004540,GO:0004654,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0006950,GO:0008144,GO:0008150,GO:0008152,GO:0008408,GO:0009056,GO:0009057,GO:0009266,GO:0009408,GO:0009628,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016020,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0016787,GO:0016788,GO:0016796,GO:0016896,GO:0017076,GO:0019001,GO:0019222,GO:0019439,GO:0030312,GO:0030551,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0034655,GO:0035438,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0050896,GO:0060255,GO:0065007,GO:0071704,GO:0071944,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 1.056e-208 665.0
PYH3_k127_7721953_0 PFAM glycosyl transferase family 51 K05366 - 2.4.1.129,3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 576.0
PYH3_k127_7721953_1 Elongation factor G C-terminus K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 312.0
PYH3_k127_7729953_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 9.344e-232 724.0
PYH3_k127_7735326_0 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
PYH3_k127_7735326_1 phosphoprotein phosphatase activity K01525 GO:0003674,GO:0003824,GO:0004551,GO:0004721,GO:0006139,GO:0006464,GO:0006470,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008138,GO:0008150,GO:0008152,GO:0008796,GO:0008803,GO:0009314,GO:0009628,GO:0009987,GO:0010165,GO:0010212,GO:0015949,GO:0016311,GO:0016462,GO:0016787,GO:0016788,GO:0016791,GO:0016817,GO:0016818,GO:0019538,GO:0034641,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0050896,GO:0055086,GO:0071704,GO:0140096,GO:1901360,GO:1901564 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 292.0
PYH3_k127_7735326_2 Methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003298 233.0
PYH3_k127_7735326_3 Domain of unknown function (DUF309) K09763 - - 0.0000000000000000000000000000000000000000000000001046 183.0
PYH3_k127_7813440_0 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 GO:0003674,GO:0003824,GO:0003849,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019438,GO:0019752,GO:0042802,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008194 516.0
PYH3_k127_7813440_1 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 443.0
PYH3_k127_7813440_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000002022 184.0
PYH3_k127_7813440_3 YacP-like NYN domain K06962 - - 0.0000000000000000000000000007335 119.0
PYH3_k127_7821078_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 1663.0
PYH3_k127_7821078_1 rRNA (guanine-N2-)-methyltransferase activity K09846,K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.210,2.1.1.304,2.1.1.333 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007421 483.0
PYH3_k127_7821078_11 Integrase core domain K07497 - - 0.0000000001439 63.0
PYH3_k127_7821078_12 Evidence 2b Function of strongly homologous gene - - - 0.000001301 51.0
PYH3_k127_7821078_13 HTH-like domain K07497 - - 0.000006437 49.0
PYH3_k127_7821078_2 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003784 454.0
PYH3_k127_7821078_3 membrane K08976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 359.0
PYH3_k127_7821078_4 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 345.0
PYH3_k127_7821078_5 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000002099 232.0
PYH3_k127_7821078_7 antisigma factor binding K03598 - - 0.0000000000000000000000000000896 123.0
PYH3_k127_7821078_8 similarity to OMNI NTL01RS2573 K07485 - - 0.000000000000000000005958 94.0
PYH3_k127_7841426_0 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 451.0
PYH3_k127_7841426_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 444.0
PYH3_k127_7841426_2 Protein of unknown function (DUF1009) K09949 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007994 425.0
PYH3_k127_7841426_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000009751 171.0
PYH3_k127_7841426_4 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.000000000000000000000000000000000006909 137.0
PYH3_k127_7884322_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K15726 - - 0.0 1067.0
PYH3_k127_7884322_1 GAF domain - - - 5.383e-300 931.0
PYH3_k127_7884322_2 Bacterial regulatory protein, Fis family K07714 - - 1.427e-219 689.0
PYH3_k127_7884322_3 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 432.0
PYH3_k127_7884322_4 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005691 302.0
PYH3_k127_7884322_5 AMP binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006224 290.0
PYH3_k127_7884322_6 serine-type endopeptidase activity K08372 - - 0.0000000000000000000000000000000000000000000000000000000001809 220.0
PYH3_k127_7884322_7 Evidence 2b Function of strongly homologous gene K04752 - - 0.0000000000000000000000004908 107.0
PYH3_k127_7884322_8 response regulator K02667 - - 0.0000000000000002168 84.0
PYH3_k127_7884322_9 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.0000000003595 63.0
PYH3_k127_7915002_0 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000001783 181.0
PYH3_k127_7915002_1 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000001156 132.0
PYH3_k127_7915002_3 PFAM nuclease (SNase domain protein) - - - 0.000000003417 59.0
PYH3_k127_792091_0 Sugar (and other) transporter K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 565.0
PYH3_k127_792091_1 imidazolonepropionase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002039 531.0
PYH3_k127_792091_2 heat shock protein binding K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006817 306.0
PYH3_k127_7974946_0 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006241 530.0
PYH3_k127_7974946_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 368.0
PYH3_k127_7974946_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008285 340.0
PYH3_k127_7974946_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000000000000000000000000000000000000000000000001249 225.0
PYH3_k127_7974946_4 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000003417 216.0
PYH3_k127_8066432_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007367 595.0
PYH3_k127_8066432_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006289 378.0
PYH3_k127_8066432_2 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003071 264.0
PYH3_k127_8066432_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008117 264.0
PYH3_k127_8066432_4 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005194 240.0
PYH3_k127_8066432_5 CoA binding domain K06929 - - 0.00000000000000000000000000000000000000000000003021 173.0
PYH3_k127_8066432_6 Domain of unknown function (DUF4112) - - - 0.00000000000000000000000007076 113.0
PYH3_k127_8071418_0 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 4.518e-269 833.0
PYH3_k127_8071418_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 4.528e-197 619.0
PYH3_k127_8071418_11 Universal stress protein family - - - 0.00000000000000000000000000000000000006317 146.0
PYH3_k127_8071418_12 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.00000000000000000000000000000004829 139.0
PYH3_k127_8071418_14 Uncharacterized conserved protein (DUF2294) - - - 0.0000000000000000000000001313 108.0
PYH3_k127_8071418_15 Belongs to the UPF0753 family K09822 - - 0.00000001803 58.0
PYH3_k127_8071418_17 Evidence 2b Function of strongly homologous gene - - - 0.00000105 61.0
PYH3_k127_8071418_18 Belongs to the UPF0753 family K09822 - - 0.00001751 57.0
PYH3_k127_8071418_19 Belongs to the UPF0753 family K09822 - - 0.0002803 51.0
PYH3_k127_8071418_2 Histidyl-tRNA synthetase K01892 - 6.1.1.21 1.727e-196 620.0
PYH3_k127_8071418_3 Sulfate permease family - - - 3.458e-194 616.0
PYH3_k127_8071418_4 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 593.0
PYH3_k127_8071418_5 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007106 477.0
PYH3_k127_8071418_6 Carboxysome Shell Carbonic Anhydrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 472.0
PYH3_k127_8071418_7 Evidence 5 No homology to any previously reported sequences - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 451.0
PYH3_k127_8071418_8 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.000000000000000000000000000000000000000009446 155.0
PYH3_k127_8071418_9 Sua5 YciO YrdC YwlC family protein K07566 - 2.7.7.87 0.0000000000000000000000000000000000000004427 153.0
PYH3_k127_8099026_0 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 338.0
PYH3_k127_8099026_1 cytochrome p450 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 317.0
PYH3_k127_8099026_2 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000002323 215.0
PYH3_k127_8099026_4 Protein of unknown function (DUF2934) - - - 0.00006785 48.0
PYH3_k127_81546_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.517e-194 625.0
PYH3_k127_81546_10 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001237 280.0
PYH3_k127_81546_11 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000152 268.0
PYH3_k127_81546_12 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000007724 265.0
PYH3_k127_81546_13 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000503 256.0
PYH3_k127_81546_14 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000001072 250.0
PYH3_k127_81546_15 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000000000000007674 198.0
PYH3_k127_81546_17 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000001178 123.0
PYH3_k127_81546_18 Mo-molybdopterin cofactor metabolic process K03636 - - 0.000000000000000000000000006429 120.0
PYH3_k127_81546_19 domain, Protein K18491 - - 0.000000000000000000084 97.0
PYH3_k127_81546_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 476.0
PYH3_k127_81546_3 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 466.0
PYH3_k127_81546_4 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 417.0
PYH3_k127_81546_5 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003392 398.0
PYH3_k127_81546_6 tRNA (guanine(37)-N(1))-methyltransferase activity K01091,K01633,K15429 - 1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 374.0
PYH3_k127_81546_7 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 327.0
PYH3_k127_81546_8 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009149 314.0
PYH3_k127_81546_9 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000138 280.0
PYH3_k127_8191506_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1085.0
PYH3_k127_8191506_1 cellulose binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 509.0
PYH3_k127_8191506_2 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 419.0
PYH3_k127_8191506_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003929 363.0
PYH3_k127_8191506_4 Protein of unknown function (DUF520) K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003251 261.0
PYH3_k127_8191506_5 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 0.0000000000000000000000000000000000001441 144.0
PYH3_k127_8191506_6 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000001967 116.0
PYH3_k127_8195588_0 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 6.204e-227 707.0
PYH3_k127_8195588_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 524.0
PYH3_k127_8195588_2 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000285 251.0
PYH3_k127_8284997_1 COG NOG29403 non supervised orthologous group - - - 0.000000000002954 72.0
PYH3_k127_8284997_2 - - - - 0.0002404 51.0
PYH3_k127_8382625_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1013.0
PYH3_k127_8382625_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 4.312e-298 924.0
PYH3_k127_8382625_10 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 358.0
PYH3_k127_8382625_11 Cytochrome c K17052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002457 331.0
PYH3_k127_8382625_12 Cytochrome c K08738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005812 315.0
PYH3_k127_8382625_13 UbiA prenyltransferase family K03179 - 2.5.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 307.0
PYH3_k127_8382625_15 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000878 259.0
PYH3_k127_8382625_17 - - - - 0.0000000000000000000000000000000000000000000319 166.0
PYH3_k127_8382625_2 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 5.711e-219 683.0
PYH3_k127_8382625_3 Cytochrome b/b6/petB K00412 - - 1.566e-212 662.0
PYH3_k127_8382625_4 Domain of unknown function (DUF3463) - - - 1.118e-205 642.0
PYH3_k127_8382625_5 Evidence 5 No homology to any previously reported sequences K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 540.0
PYH3_k127_8382625_6 oxidoreductase activity, acting on diphenols and related substances as donors K00240,K03886 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 489.0
PYH3_k127_8382625_7 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 419.0
PYH3_k127_8382625_8 Cytochrome c K02305,K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006779 425.0
PYH3_k127_8382625_9 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007779 380.0
PYH3_k127_855285_0 ATPase activity K01990,K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 471.0
PYH3_k127_855285_1 peptidoglycan binding K03642 - - 0.00000000000000000000000000000000000000000000000001723 186.0
PYH3_k127_855285_2 - K01992 - - 0.000000000000000000000000000007873 120.0
PYH3_k127_8597550_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004295 419.0
PYH3_k127_8597550_1 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 323.0
PYH3_k127_8597550_2 Belongs to the peptidase M50B family - - - 0.000000000003369 68.0
PYH3_k127_8597550_3 phosphorelay sensor kinase activity K16923 - - 0.0000001464 64.0
PYH3_k127_8599192_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003765 406.0
PYH3_k127_8599192_1 Isochorismatase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007842 257.0
PYH3_k127_8599192_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000000001791 169.0
PYH3_k127_8599192_3 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000001866 143.0
PYH3_k127_8599192_4 Putative prokaryotic signal transducing protein - - - 0.0000000000000000004688 92.0
PYH3_k127_8599192_5 Protein of unknown function (DUF3703) - - - 0.000000002415 60.0
PYH3_k127_8613762_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 523.0
PYH3_k127_8613762_1 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 434.0
PYH3_k127_8613762_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000155 292.0
PYH3_k127_8613762_4 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000008514 235.0
PYH3_k127_8613762_5 recombinase XerD K04763 - - 0.00000000000000000000000000000000000000000000000000000873 201.0
PYH3_k127_8613762_6 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.000000004149 59.0
PYH3_k127_8617228_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 394.0
PYH3_k127_8617228_1 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 291.0
PYH3_k127_8617228_2 Glycoprotease family K14742 - - 0.000000000000000000000000002273 115.0
PYH3_k127_8665009_0 MacB-like periplasmic core domain K02004 - - 7.568e-266 844.0
PYH3_k127_8665009_1 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 514.0
PYH3_k127_8665009_2 lipoprotein transporter activity K02003 - - 0.000000000000000000000001062 104.0
PYH3_k127_8665009_3 response regulator - - - 0.00000000000000000001288 94.0
PYH3_k127_8684371_0 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004235 500.0
PYH3_k127_8684371_1 Pentapeptide repeats (9 copies) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007905 437.0
PYH3_k127_8684371_2 ErfK ybiS ycfS ynhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008677 314.0
PYH3_k127_8684371_3 IMP dehydrogenase activity K07182 - - 0.00000000000000000000000000000000000000000000000000000000000007102 215.0
PYH3_k127_8684371_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000002493 54.0
PYH3_k127_8687671_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 544.0
PYH3_k127_8687671_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 514.0
PYH3_k127_8687671_2 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008136 399.0
PYH3_k127_8687671_3 Peptidase C26 K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 342.0
PYH3_k127_8687671_4 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000006599 252.0
PYH3_k127_8691441_0 Represses a number of genes involved in the response to DNA damage (SOS response) K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000267 222.0
PYH3_k127_8691441_1 Bacterial regulatory protein, Fis family K07715 - - 0.00000000000000000000000000000000000004909 144.0
PYH3_k127_8691441_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage - - - 0.00000000000000008707 89.0
PYH3_k127_8691441_3 - - - - 0.000009161 49.0
PYH3_k127_8713813_0 TIGRFAM Polyphosphate nucleotide phosphotransferase, PPK2 K00937 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004546 451.0
PYH3_k127_8713813_1 Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity K06188 - - 0.000000000000000000000000000000000000000000000000001694 185.0
PYH3_k127_8713813_2 Methyltransferase domain - - - 0.000000000000000000000000000006211 124.0
PYH3_k127_8733846_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 4.183e-223 696.0
PYH3_k127_8733846_1 Cell wall formation K01921 - 6.3.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 457.0
PYH3_k127_8733846_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005289 416.0
PYH3_k127_8733846_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000001322 214.0
PYH3_k127_8733846_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.000000000000000000000000000000000000000000000000000000284 205.0
PYH3_k127_8733846_5 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.0000000000000000000000000000000000000000000000000001048 187.0
PYH3_k127_8735197_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 4.45e-263 815.0
PYH3_k127_8735197_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 376.0
PYH3_k127_8735197_2 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002478 253.0
PYH3_k127_8735197_3 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009071 249.0
PYH3_k127_8735197_4 nitric oxide dioxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000002655 230.0
PYH3_k127_8759958_0 AcrB/AcrD/AcrF family - - - 5.143e-314 970.0
PYH3_k127_8759958_2 Protein of unknown function (DUF2914) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 475.0
PYH3_k127_8759958_3 Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine K00797,K01611 - 2.5.1.16,4.1.1.50 0.000000000000000000000000000000000000000000000000000001495 196.0
PYH3_k127_8759958_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000001516 170.0
PYH3_k127_8759958_6 Sterol carrier protein - - - 0.0000000000000000000000000000000000000000101 156.0
PYH3_k127_8759958_8 Binds the second messenger bis-(3'-5') cyclic dimeric guanosine monophosphate (c-di-GMP). Can bind two c-di-GMP molecules per monomer. May play a role in bacterial second- messenger regulated processes. Binding to c-di-GMP induces a conformational change of the C- and N-termini resulting in the exposure of a highly negative surface on one side of the protein to a - - - 0.0009359 48.0
PYH3_k127_8768317_0 WD40-like Beta Propeller Repeat K03641 - - 4.193e-224 702.0
PYH3_k127_8768317_1 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000415 279.0
PYH3_k127_8768317_2 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004624 274.0
PYH3_k127_8768317_3 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000000000000000001532 219.0
PYH3_k127_8768317_4 energy transducer activity K03646,K03832 - - 0.000000000000000000000000000000000000000000000000009581 195.0
PYH3_k127_8798532_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K08070 - 1.3.1.74 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 534.0
PYH3_k127_8798532_1 Proteasomal ATPase OB/ID domain K13527 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005483 475.0
PYH3_k127_8798532_2 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 417.0
PYH3_k127_8798532_3 Evidence 5 No homology to any previously reported sequences K02450,K07126 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 299.0
PYH3_k127_8798532_4 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000005295 263.0
PYH3_k127_8798532_6 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000004236 197.0
PYH3_k127_8798532_7 bis(5'-adenosyl)-triphosphatase activity - - - 0.0000000000000000000000000000000000000000000000000006636 189.0
PYH3_k127_8798532_8 acetyltransferase - - - 0.0000000000000000000000000000000001959 136.0
PYH3_k127_8805989_0 DNA-directed DNA polymerase activity K02347,K04477 - - 2.457e-202 638.0
PYH3_k127_8805989_1 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005263 608.0
PYH3_k127_8805989_2 signal-transduction protein containing cAMP-binding and CBS domains K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 311.0
PYH3_k127_8805989_3 Phosphoribosyl transferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001568 252.0
PYH3_k127_8805989_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000000002296 240.0
PYH3_k127_8832932_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 9.541e-277 859.0
PYH3_k127_8832932_1 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 6.861e-207 655.0
PYH3_k127_8832932_2 Histidyl-tRNA synthetase K02502 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007291 439.0
PYH3_k127_8832932_3 Evidence 2b Function of strongly homologous gene - - - 0.0000000000000000003946 87.0
PYH3_k127_8876036_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1337.0
PYH3_k127_8876036_1 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1114.0
PYH3_k127_8876036_10 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000006807 263.0
PYH3_k127_8876036_11 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000002889 216.0
PYH3_k127_8876036_12 adenosylhomocysteine nucleosidase activity K01243,K03527 - 1.17.7.4,3.2.2.9 0.00000000000000000000000000000000000000000000000000000006034 211.0
PYH3_k127_8876036_2 Surface antigen - - - 6.474e-197 620.0
PYH3_k127_8876036_3 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008009 555.0
PYH3_k127_8876036_4 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 416.0
PYH3_k127_8876036_5 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001812 393.0
PYH3_k127_8876036_6 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000312 393.0
PYH3_k127_8876036_7 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004078 368.0
PYH3_k127_8876036_8 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005687 364.0
PYH3_k127_8876036_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005972 272.0
PYH3_k127_8882095_0 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004839 638.0
PYH3_k127_8882095_1 Alpha/beta hydrolase family K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001411 347.0
PYH3_k127_8882095_2 thiolester hydrolase activity K06889,K07000 - - 0.000000000000000000000000000004592 121.0
PYH3_k127_8989865_0 Sigma-54 interaction domain K07714 - - 1.036e-242 754.0
PYH3_k127_8989865_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K00384,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 490.0
PYH3_k127_8989865_2 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001921 317.0
PYH3_k127_8989865_3 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008008 256.0
PYH3_k127_8989865_4 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000002942 213.0
PYH3_k127_8989865_5 cellulase activity - - - 0.0000000000000000000000004265 120.0
PYH3_k127_8992776_0 Transposase IS116 IS110 IS902 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 514.0
PYH3_k127_8992776_1 cobalamin binding K21089,K21972,K22491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005507 460.0
PYH3_k127_8992776_2 PFAM NapC NirT cytochrome c K02569 - - 0.0000000000000000000000000000000000000000000000000000002313 196.0
PYH3_k127_8992776_3 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000005712 178.0
PYH3_k127_8992776_4 Oxidoreductase FAD-binding domain K16246 GO:0003674,GO:0003824,GO:0004497,GO:0006725,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016491,GO:0016705,GO:0016709,GO:0018662,GO:0018958,GO:0018959,GO:0019336,GO:0019439,GO:0044237,GO:0044248,GO:0046191,GO:0055114,GO:0071704,GO:1901360,GO:1901361,GO:1901575,GO:1901615,GO:1901616 - 0.00000000000000000000000000000000000001389 157.0
PYH3_k127_8992776_5 PFAM NapC NirT cytochrome c K02569 - - 0.0000000000000000001846 91.0
PYH3_k127_8992776_7 cobalamin binding K21089,K21972,K22491 - - 0.00000000002762 68.0
PYH3_k127_9019277_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009498 353.0
PYH3_k127_9019277_1 Transposase K01991,K02557,K07161,K07484 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 316.0
PYH3_k127_9019277_2 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 294.0
PYH3_k127_9019277_3 Belongs to the ompA family K03640 - - 0.000000000000000002392 84.0
PYH3_k127_9175447_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 3.13e-230 719.0
PYH3_k127_9175447_1 Aminotransferase class-III K03918,K07250,K20428 - 2.6.1.19,2.6.1.22,2.6.1.33,2.6.1.36 8.829e-216 676.0
PYH3_k127_9175447_10 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K05305,K16881 - 2.7.1.52,2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000001773 211.0
PYH3_k127_9175447_11 PIN domain - - - 0.000000000000000000000000000000000000000000008111 166.0
PYH3_k127_9175447_12 Protein export membrane protein K03296,K18138 - - 0.0000000000000000000000000000000005207 140.0
PYH3_k127_9175447_13 response to nickel cation K07723 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000004852 97.0
PYH3_k127_9175447_15 Regulator of microtubule dynamics protein 1 - - - 0.000000004675 66.0
PYH3_k127_9175447_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella K18691 GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007941 471.0
PYH3_k127_9175447_3 Biotin-lipoyl like K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004161 398.0
PYH3_k127_9175447_4 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 330.0
PYH3_k127_9175447_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 332.0
PYH3_k127_9175447_6 lysyltransferase activity K07027 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007287 277.0
PYH3_k127_9175447_7 Glutathione synthase Ribosomal protein S6 modification enzyme (Glutaminyl transferase) K03802,K05844 - 6.3.2.29,6.3.2.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000248 261.0
PYH3_k127_9175447_8 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01560,K07025,K20862 - 3.1.3.102,3.1.3.104,3.8.1.2 0.00000000000000000000000000000000000000000000000000000000008519 213.0
PYH3_k127_9175447_9 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000002579 205.0
PYH3_k127_9358596_0 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000339 409.0
PYH3_k127_9358596_1 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007011 353.0
PYH3_k127_9358596_2 Protein of unknown function (DUF502) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002748 246.0
PYH3_k127_9358596_3 acetyltransferase - - - 0.00000000000000000000000000000000000000000000003255 184.0
PYH3_k127_9358596_5 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000000000000007285 133.0
PYH3_k127_9358596_8 - - - - 0.000000000000135 73.0
PYH3_k127_9374891_0 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.0 1041.0
PYH3_k127_9374891_1 2 iron, 2 sulfur cluster binding K04487,K13643 - 2.8.1.7 0.000000000000000000000000000000000000000000000000003665 185.0
PYH3_k127_9374891_2 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000003299 173.0
PYH3_k127_9397431_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 3.013e-238 739.0
PYH3_k127_9397431_1 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 552.0
PYH3_k127_9397431_2 ThiF family K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 470.0
PYH3_k127_9397431_4 thiamine diphosphate biosynthetic process K03154 - - 0.00000000000000000000000000263 112.0
PYH3_k127_9470716_0 helicase activity K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002238 568.0
PYH3_k127_9470716_2 RNA recognition motif - - - 0.0000000000000000000000000000000000000000005382 160.0
PYH3_k127_9470716_3 PFAM NapC NirT cytochrome c K02569 - - 0.00000000000000000000004082 99.0
PYH3_k127_9470716_4 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.00002387 48.0
PYH3_k127_9483158_1 DNA-binding transcription factor activity - - - 0.000000000000000000000000000000000000002747 160.0
PYH3_k127_9546120_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004243 359.0
PYH3_k127_9546120_3 cell adhesion K02650 - - 0.000000000000000000000000007283 113.0
PYH3_k127_9573538_0 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000302 577.0
PYH3_k127_9573538_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007289 407.0
PYH3_k127_9573538_2 Zincin-like metallopeptidase - - - 0.00000000000000000000000000000000000000000003436 164.0
PYH3_k127_9573538_3 gas vesicle protein - - - 0.0000000000000000000007405 98.0
PYH3_k127_961852_0 belongs to the aldehyde dehydrogenase family K00128 GO:0003674,GO:0003824,GO:0004029,GO:0006081,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016620,GO:0016903,GO:0044237,GO:0055114,GO:0071704 1.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 490.0
PYH3_k127_961852_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 481.0
PYH3_k127_961852_2 Transcriptional regulatory protein, C terminal K07658 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003239 355.0
PYH3_k127_961852_3 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004245 305.0
PYH3_k127_961852_4 CHAD - - - 0.0000000000000000000000000000000000000000000000000000007172 211.0
PYH3_k127_9666434_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 3.467e-212 664.0
PYH3_k127_9666434_1 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004247 458.0
PYH3_k127_9666434_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008387 422.0
PYH3_k127_9666434_3 PFAM TrkA-C domain protein K11105 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 408.0
PYH3_k127_9666434_4 lipid binding K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 296.0
PYH3_k127_9666434_7 Protein of unknown function DUF72 - - - 0.0002075 48.0
PYH3_k127_9693352_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 473.0
PYH3_k127_9693352_1 Belongs to the enoyl-CoA hydratase isomerase family K07515 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003857,GO:0003985,GO:0003988,GO:0004300,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005743,GO:0005759,GO:0005777,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0007275,GO:0007568,GO:0008150,GO:0008152,GO:0008340,GO:0009056,GO:0009062,GO:0009295,GO:0009605,GO:0009611,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010259,GO:0016020,GO:0016042,GO:0016054,GO:0016407,GO:0016408,GO:0016453,GO:0016491,GO:0016507,GO:0016508,GO:0016509,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0016829,GO:0016835,GO:0016836,GO:0017076,GO:0019395,GO:0019752,GO:0019866,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032501,GO:0032502,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032868,GO:0032991,GO:0033218,GO:0034440,GO:0036094,GO:0036125,GO:0042060,GO:0042221,GO:0042493,GO:0042579,GO:0042594,GO:0042645,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043434,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046395,GO:0048037,GO:0048856,GO:0050662,GO:0050896,GO:0051287,GO:0055114,GO:0070013,GO:0071704,GO:0072329,GO:0097159,GO:0097367,GO:0098798,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901652,GO:1901681,GO:1901698,GO:1901700 1.1.1.211,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 383.0
PYH3_k127_9693352_2 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.00000000000000000000000000000000000000000000000005952 193.0
PYH3_k127_9693352_3 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000002039 64.0
PYH3_k127_9693352_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000001179 53.0
PYH3_k127_9693352_5 Alpha-beta hydrolase superfamily - - - 0.00003785 56.0
PYH3_k127_99151_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002509 514.0
PYH3_k127_99151_2 Preprotein translocase SecG subunit K03075 - - 0.000003296 50.0