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Overview

ID MAG03218
Name PYH3_bin.22
Sample SMP0075
Taxonomy
Kingdom Archaea
Phylum Thermoproteota
Class Bathyarchaeia
Order 40CM-2-53-6
Family 40CM-2-53-6
Genus
Species
Assembly information
Completeness (%) 82.3
Contamination (%) 1.36
GC content (%) 53.0
N50 (bp) 13,243
Genome size (bp) 1,836,494

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1724

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1002061_0 acetoacetate decarboxylase K01574 - 4.1.1.4 0.0000000000000000000000000000000000000003787 159.0
PYH3_k127_1002061_1 CAAX protease self-immunity - - - 0.0000000000000000000000000000009243 131.0
PYH3_k127_1002061_2 Transcriptional regulator K07729 - - 0.000000000000000000000002871 102.0
PYH3_k127_1002061_3 - - - - 0.00005834 50.0
PYH3_k127_1063036_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1034.0
PYH3_k127_1063036_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 3.928e-249 800.0
PYH3_k127_1063036_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0002224 46.0
PYH3_k127_1063036_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 308.0
PYH3_k127_1063036_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.00000000000000000000000000000000000000000000000000000000001847 217.0
PYH3_k127_1063036_4 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000001019 208.0
PYH3_k127_1063036_5 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.000000000000000000000000000000000000000000002289 175.0
PYH3_k127_1063036_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.0000000000000000000000003743 107.0
PYH3_k127_1063036_7 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.0000000000009053 74.0
PYH3_k127_1063036_8 PFAM Ribosomal L18ae LX protein domain K02944 - - 0.00000004277 57.0
PYH3_k127_1063036_9 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.00001872 47.0
PYH3_k127_1126304_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 1.918e-196 631.0
PYH3_k127_1126304_1 SMART Elongator protein 3 MiaB NifB K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 497.0
PYH3_k127_1126304_10 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000002391 71.0
PYH3_k127_1126304_11 snRNP Sm proteins K04796 - - 0.000000000003366 69.0
PYH3_k127_1126304_12 - - - - 0.000000001887 62.0
PYH3_k127_1126304_13 Helix-turn-helix domain - - - 0.000008553 57.0
PYH3_k127_1126304_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 465.0
PYH3_k127_1126304_3 Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006595 415.0
PYH3_k127_1126304_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 404.0
PYH3_k127_1126304_5 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000001809 237.0
PYH3_k127_1126304_6 Major facilitator superfamily K08153,K08221 - - 0.00000000000000000000000000000000000003378 159.0
PYH3_k127_1126304_7 major facilitator superfamily K08153,K08221 - - 0.00000000000000000000000000003202 131.0
PYH3_k127_1126304_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006886,GO:0008104,GO:0008150,GO:0008320,GO:0008565,GO:0009977,GO:0015031,GO:0015291,GO:0015399,GO:0015405,GO:0015450,GO:0015833,GO:0016020,GO:0022804,GO:0022857,GO:0022884,GO:0032991,GO:0033036,GO:0033281,GO:0034613,GO:0042886,GO:0042887,GO:0043953,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0046907,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0055085,GO:0065002,GO:0070727,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0098796,GO:0098797,GO:1904680 - 0.0000000000000000000006456 106.0
PYH3_k127_1126304_9 - - - - 0.000000000000000000001089 100.0
PYH3_k127_11607_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000003168 214.0
PYH3_k127_11607_2 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000000000000000004838 125.0
PYH3_k127_11607_3 PFAM amino acid-binding ACT domain protein - - - 0.000000000000000004259 89.0
PYH3_k127_11607_4 PFAM Metallophosphoesterase K03547 - - 0.000000000000001679 89.0
PYH3_k127_11607_5 Protein of unknown function (DUF998) - - - 0.00000000008752 65.0
PYH3_k127_11607_6 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0000098,GO:0003674,GO:0003824,GO:0004122,GO:0004124,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006555,GO:0006563,GO:0006790,GO:0006807,GO:0008134,GO:0008144,GO:0008150,GO:0008152,GO:0008284,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009066,GO:0009068,GO:0009069,GO:0009070,GO:0009087,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016740,GO:0016765,GO:0016829,GO:0016835,GO:0016836,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0022607,GO:0030170,GO:0032991,GO:0032993,GO:0036094,GO:0042127,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043388,GO:0043436,GO:0043933,GO:0044085,GO:0044093,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044272,GO:0044273,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0048518,GO:0048522,GO:0050662,GO:0050789,GO:0050794,GO:0051098,GO:0051099,GO:0051101,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051291,GO:0065003,GO:0065007,GO:0065009,GO:0070279,GO:0071704,GO:0071840,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607,GO:1904796,GO:1904798,GO:2000677,GO:2000679 2.5.1.47 0.0000179 51.0
PYH3_k127_125408_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 2.729e-197 625.0
PYH3_k127_125408_2 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000002331 90.0
PYH3_k127_125408_3 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000001543 61.0
PYH3_k127_1256250_0 Beta-eliminating lyase K01667 - 4.1.99.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008358 601.0
PYH3_k127_1256250_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 583.0
PYH3_k127_1256250_10 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000009248 160.0
PYH3_k127_1256250_11 Belongs to the UPF0273 family - - - 0.000000000000000000000000000000000002538 148.0
PYH3_k127_1256250_12 Pfam:DUF385 - - - 0.0000000000000000000000000000000006663 134.0
PYH3_k127_1256250_13 DJ-1/PfpI family K18199 - 4.2.1.103 0.0000000000000000000000000005284 121.0
PYH3_k127_1256250_14 Transcriptional regulator, TrmB - - - 0.0000000000000000000000004204 116.0
PYH3_k127_1256250_15 membrane protein domain - - - 0.000000000000000000001944 101.0
PYH3_k127_1256250_16 COG1522 Transcriptional regulators - - - 0.00000000000000005005 82.0
PYH3_k127_1256250_2 Aldo/keto reductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 450.0
PYH3_k127_1256250_3 Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). HdrE may be responsible for anchoring the complex to the membrane K08265,K16887 GO:0003674,GO:0003824,GO:0005575,GO:0006091,GO:0008150,GO:0008152,GO:0009058,GO:0009061,GO:0009987,GO:0015947,GO:0015948,GO:0015975,GO:0015980,GO:0016020,GO:0016021,GO:0016491,GO:0016667,GO:0031224,GO:0043446,GO:0043447,GO:0044237,GO:0044249,GO:0044425,GO:0045333,GO:0051912,GO:0055114,GO:0071704,GO:1901576 1.8.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 392.0
PYH3_k127_1256250_4 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004397 380.0
PYH3_k127_1256250_5 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009318 317.0
PYH3_k127_1256250_6 Histone deacetylase domain K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 302.0
PYH3_k127_1256250_7 TatD related DNase K03424 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 290.0
PYH3_k127_1256250_8 helix_turn_helix ASNC type - - - 0.00000000000000000000000000000000000000000002462 166.0
PYH3_k127_1256250_9 Protein of unknown function (DUF4013) - - - 0.00000000000000000000000000000000000000000008109 170.0
PYH3_k127_1280193_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008826 478.0
PYH3_k127_1280193_1 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000001852 228.0
PYH3_k127_1280348_0 Transketolase, central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007334 384.0
PYH3_k127_1280348_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 310.0
PYH3_k127_1280348_2 Dehydrogenase K00008 - 1.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 306.0
PYH3_k127_1280348_3 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 291.0
PYH3_k127_1280348_4 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009876 286.0
PYH3_k127_137707_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 1.485e-218 692.0
PYH3_k127_137707_1 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 1.555e-213 683.0
PYH3_k127_137707_10 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034,K15582 - - 0.000000000000000000000000000000000000000000000000000000000000000000004425 236.0
PYH3_k127_137707_11 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.00000000000000000000000000000000000000000000000000000000000000000001191 246.0
PYH3_k127_137707_12 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000000000000000019 222.0
PYH3_k127_137707_13 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000001456 226.0
PYH3_k127_137707_14 - - - - 0.00000000000000000000000000000000000000000000000002249 188.0
PYH3_k127_137707_15 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000208 123.0
PYH3_k127_137707_16 PFAM Cupin 2, conserved barrel domain protein K11312 - - 0.0000000000000711 75.0
PYH3_k127_137707_17 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000005411 72.0
PYH3_k127_137707_18 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases - - - 0.00000000003763 74.0
PYH3_k127_137707_2 Amidohydrolase family K06015 - 3.5.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 452.0
PYH3_k127_137707_3 Leucyl aminopeptidase (Aminopeptidase t) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 387.0
PYH3_k127_137707_4 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003689 382.0
PYH3_k127_137707_5 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 356.0
PYH3_k127_137707_6 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003851 327.0
PYH3_k127_137707_7 Extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006458 288.0
PYH3_k127_137707_8 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002802 280.0
PYH3_k127_137707_9 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002866 269.0
PYH3_k127_1401093_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 389.0
PYH3_k127_1451196_0 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008818 622.0
PYH3_k127_1451196_1 radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004793 268.0
PYH3_k127_1451196_2 Rubrerythrin - - - 0.00000000000001146 74.0
PYH3_k127_1476084_0 bacterial OsmY and nodulation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000006929 231.0
PYH3_k127_1476084_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000001274 212.0
PYH3_k127_1477814_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 3.169e-197 625.0
PYH3_k127_1477814_1 PFAM PfkB domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000003928 230.0
PYH3_k127_1477814_2 ribosomal protein K02976 - - 0.000000000000000000000000001307 114.0
PYH3_k127_1478264_0 ABC transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002284 265.0
PYH3_k127_1478264_1 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000001345 194.0
PYH3_k127_1478264_2 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000002032 162.0
PYH3_k127_1478264_3 TCP-1/cpn60 chaperonin family K22447 - - 0.000000000000000000575 89.0
PYH3_k127_152001_0 alcohol dehydrogenase K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000002972 263.0
PYH3_k127_152001_1 Nitroreductase family - - - 0.0000000000000000000000000000000000000001729 158.0
PYH3_k127_152001_2 - - - - 0.0000000000000000000005831 104.0
PYH3_k127_152001_3 - - - - 0.00000000000001803 78.0
PYH3_k127_152001_4 - - - - 0.00000000005825 64.0
PYH3_k127_1528644_0 Heat shock 70 kDa protein K04043 - - 2.704e-231 731.0
PYH3_k127_1528644_1 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008922 477.0
PYH3_k127_1528644_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 385.0
PYH3_k127_1528644_3 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000006785 181.0
PYH3_k127_1528644_4 Thiamine transporter YuaJ K16789 - - 0.0000000000000000000000000000000000000000001431 166.0
PYH3_k127_1528644_5 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000000000007355 123.0
PYH3_k127_1528644_6 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.00000000000000000007515 91.0
PYH3_k127_1536173_0 PFAM aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 501.0
PYH3_k127_1536173_1 PFAM iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 310.0
PYH3_k127_1536173_2 NAD-dependent protein deacetylase which modulates the activities of several proteins which are inactive in their acetylated form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001241 255.0
PYH3_k127_1536173_3 Ankyrin repeats (3 copies) - - - 0.00007398 52.0
PYH3_k127_1540925_0 Binds to the 23S rRNA K02922 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000001207 100.0
PYH3_k127_1540925_1 snRNP Sm proteins K04796 - - 0.00000000000000000000002575 101.0
PYH3_k127_1540925_2 PFAM PUA domain containing protein K07575 - - 0.0000000000000000000002274 103.0
PYH3_k127_1540925_3 Pfam:DUF552 K09152 - - 0.0000000000000005187 82.0
PYH3_k127_1570646_0 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000000000000000005723 194.0
PYH3_k127_1570646_1 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000004584 193.0
PYH3_k127_1570646_2 - K07149 - - 0.00000000000000000000000000000000000001128 153.0
PYH3_k127_1570646_3 Methyltransferase domain K06987 - - 0.0000000000000000000000000000000004967 141.0
PYH3_k127_1594077_0 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 332.0
PYH3_k127_1594077_1 Mn2 dependent serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 301.0
PYH3_k127_1594077_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000002173 171.0
PYH3_k127_1602050_0 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases K01090 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000004335 224.0
PYH3_k127_1602050_1 PFAM Major Facilitator Superfamily - - - 0.000002114 51.0
PYH3_k127_1604327_0 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000691 443.0
PYH3_k127_1604327_1 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000002271 229.0
PYH3_k127_1604327_2 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000265 181.0
PYH3_k127_1604327_3 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000551 170.0
PYH3_k127_1604327_4 EamA-like transporter family - - - 0.000000000000000000000003565 113.0
PYH3_k127_1604327_5 - - - - 0.000000000000000001199 93.0
PYH3_k127_1604327_6 COG1522 Transcriptional regulators - - - 0.00000000000000001369 85.0
PYH3_k127_1604327_7 Heavy metal translocating P-type atpase - - - 0.0000000000002986 79.0
PYH3_k127_1604327_8 Conserved protein implicated in secretion - - - 0.000000000121 64.0
PYH3_k127_165382_0 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002386 255.0
PYH3_k127_165382_1 beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000003462 203.0
PYH3_k127_165382_2 Cobalamin adenosyltransferase K00798 - 2.5.1.17 0.000000000000000000000000000002501 124.0
PYH3_k127_165382_3 extracellular matrix structural constituent - - - 0.0000000000000000000000197 115.0
PYH3_k127_165382_4 PFAM ABC-2 type transporter K01992 - - 0.0000000000000001418 92.0
PYH3_k127_165382_5 ABC-2 family transporter protein K01992 - - 0.00000006124 64.0
PYH3_k127_1674456_0 PFAM oxidoreductase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 428.0
PYH3_k127_1674456_1 PFAM CobQ CobB MinD ParA nucleotide binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000137 261.0
PYH3_k127_1674456_2 Sigma factor PP2C-like phosphatases - - - 0.0000000000000000000000000000000000000000000000000000000002128 213.0
PYH3_k127_1674456_3 Subtilase family - - - 0.000000000000000004119 99.0
PYH3_k127_1674456_4 PFAM protein phosphatase 2C K01090 - 3.1.3.16 0.000004603 51.0
PYH3_k127_1722052_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008707 333.0
PYH3_k127_1722052_1 Catalyzes the GTP-dependent successive addition of two or more gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form coenzyme F420-0-glutamyl-glutamate (F420-2) or polyglutamated F420 derivatives K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000005378 210.0
PYH3_k127_1722052_10 Glycosyltransferase, group 2 family protein - - - 0.00001008 57.0
PYH3_k127_1722052_11 Lipocalin-like domain - - - 0.0001282 46.0
PYH3_k127_1722052_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000004351 210.0
PYH3_k127_1722052_3 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000447 161.0
PYH3_k127_1722052_4 Arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000001451 140.0
PYH3_k127_1722052_5 Belongs to the arginase family K01479,K01480 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009445,GO:0009446,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0030145,GO:0034641,GO:0042401,GO:0043167,GO:0043169,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11,3.5.3.8 0.00000000000000000000128 99.0
PYH3_k127_1722052_6 RNA-binding protein contains TRAM domain - - - 0.0000000000000000004713 88.0
PYH3_k127_1722052_7 - - - - 0.0000000000000168 76.0
PYH3_k127_1722052_8 Domain of unknown function (DUF1508) K09946 - - 0.0000000000005972 70.0
PYH3_k127_1722052_9 Lipocalin-like domain - - - 0.0000000002456 66.0
PYH3_k127_1722242_0 PIN domain - - - 0.0000000000000000000000000000001449 131.0
PYH3_k127_1722242_1 SpoVT / AbrB like domain - - - 0.0000000000000859 74.0
PYH3_k127_1734941_0 Psort location Cytoplasmic, score 8.87 K11358 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 332.0
PYH3_k127_1734941_1 oligoendopeptidase F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 325.0
PYH3_k127_1734941_2 Luciferase-like monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000006324 205.0
PYH3_k127_1734941_3 Aminotransferase K00812,K22457 GO:0003674,GO:0003824,GO:0008483,GO:0016740,GO:0016769,GO:0047297 2.6.1.1,2.6.1.14 0.000000000000000000000000000000000000000000001923 175.0
PYH3_k127_1734941_4 transferase activity, transferring glycosyl groups - - - 0.00000000007831 69.0
PYH3_k127_1840257_0 GlcNAc-PI de-N-acetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000008605 242.0
PYH3_k127_1840257_1 Belongs to the arginase family K01476 - 3.5.3.1 0.000000000000000000000000000000000000000000000006547 183.0
PYH3_k127_1840257_2 MFS_1 like family - - - 0.0000000000000000000000000000000000655 148.0
PYH3_k127_1840257_3 - - - - 0.0000000000000000000000000000000002137 145.0
PYH3_k127_1840257_4 - - - - 0.0000000000000000000000001372 110.0
PYH3_k127_1840257_5 Haloacid dehalogenase-like hydrolase - - - 0.000000000000000195 89.0
PYH3_k127_1840257_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000002719 80.0
PYH3_k127_1842434_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 2.604e-217 677.0
PYH3_k127_1842434_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531 - 3.6.3.2 8.881e-210 680.0
PYH3_k127_1842434_10 pyridoxamine 5-phosphate - - - 0.000000000000652 75.0
PYH3_k127_1842434_11 Dimerisation domain of Zinc Transporter - - - 0.00007871 53.0
PYH3_k127_1842434_12 Staygreen protein - - - 0.0008326 44.0
PYH3_k127_1842434_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004867 580.0
PYH3_k127_1842434_3 Glycine cleavage system P-protein K00281,K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 533.0
PYH3_k127_1842434_4 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 369.0
PYH3_k127_1842434_5 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002487 363.0
PYH3_k127_1842434_6 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 336.0
PYH3_k127_1842434_7 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000134 247.0
PYH3_k127_1842434_8 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000006838 194.0
PYH3_k127_1842434_9 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000442 123.0
PYH3_k127_1961011_0 ERCC4 domain K10896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001777 417.0
PYH3_k127_1961011_1 Protein of unknown function (DUF763) K09003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 406.0
PYH3_k127_1961011_2 Cys/Met metabolism PLP-dependent enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005981 318.0
PYH3_k127_1961011_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000001219 228.0
PYH3_k127_1961011_4 Predicted metal-binding protein (DUF2284) - - - 0.0000000000000000000000000000000000000000000000000000001925 202.0
PYH3_k127_1961011_5 Methionine synthase B12-binding module cap domain protein K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000001428 175.0
PYH3_k127_1961011_6 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000001747 140.0
PYH3_k127_1961011_8 Belongs to the UPF0145 family - - - 0.00000000002393 64.0
PYH3_k127_2087982_0 ABC-type transport system, involved in lipoprotein release, permease component K02004 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002954 275.0
PYH3_k127_2087982_1 PFAM ABC transporter K02003,K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008507 266.0
PYH3_k127_2124226_0 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 338.0
PYH3_k127_2124226_1 - - - - 0.0000002778 52.0
PYH3_k127_2285349_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 1.105e-240 757.0
PYH3_k127_2285349_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.756e-211 666.0
PYH3_k127_2285349_10 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000001108 106.0
PYH3_k127_2285349_11 PFAM 2-nitropropane dioxygenase NPD K00459 - 1.13.12.16 0.000000000000000000000006086 103.0
PYH3_k127_2285349_12 Peptidase C13 family - - - 0.0000000000000000000001491 112.0
PYH3_k127_2285349_13 Contacts the emerging nascent chain on the ribosome K03626 - - 0.000000000000000000001735 98.0
PYH3_k127_2285349_14 Uncharacterized protein conserved in archaea (DUF2110) - - - 0.000000000000000000009136 102.0
PYH3_k127_2285349_15 Transcriptional regulator K07332 - - 0.00000000000000000001026 101.0
PYH3_k127_2285349_16 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000001898 84.0
PYH3_k127_2285349_17 HD domain K07023 - - 0.00000000000008147 82.0
PYH3_k127_2285349_18 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.0000000000001643 78.0
PYH3_k127_2285349_19 Maintenance of mitochondrial structure and function K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000001097 64.0
PYH3_k127_2285349_2 aminopeptidase activity K19689 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000511 278.0
PYH3_k127_2285349_20 Sap, sulfolipid-1-addressing protein - - - 0.0000007293 59.0
PYH3_k127_2285349_3 PFAM Pyridine nucleotide-disulphide oxidoreductase K00529 - 1.18.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000988 275.0
PYH3_k127_2285349_4 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000003643 200.0
PYH3_k127_2285349_5 Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation complexes. Seems to translocate with the RNA polymerase following initiation and acts by binding to the non template strand of the transcription bubble in elongation complexes K03136 - - 0.000000000000000000000000000000000000000001439 162.0
PYH3_k127_2285349_6 PFAM Biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000001064 163.0
PYH3_k127_2285349_7 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000000000008737 159.0
PYH3_k127_2285349_8 PUA domain containing protein K07398 - - 0.000000000000000000000000000000003566 134.0
PYH3_k127_2285349_9 - - - - 0.000000000000000000000000001436 115.0
PYH3_k127_2470660_0 Belongs to the RtcB family K14415 GO:0000394,GO:0003674,GO:0003824,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 6.5.1.3 1.811e-197 628.0
PYH3_k127_2470660_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K09759 - 6.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008949 465.0
PYH3_k127_2470660_10 TIGRFAM geranylgeranyl reductase - - - 0.00000000000000000000000000000000000000004039 166.0
PYH3_k127_2470660_11 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000009512 139.0
PYH3_k127_2470660_12 Transcription elongation factor - - - 0.00000000000000000001636 97.0
PYH3_k127_2470660_13 TIGRFAM DNA-binding protein, Tfx family K09714 - - 0.0000000000000000009225 92.0
PYH3_k127_2470660_14 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07025 - - 0.000000000000003027 85.0
PYH3_k127_2470660_2 Fe-S oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 430.0
PYH3_k127_2470660_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 351.0
PYH3_k127_2470660_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 347.0
PYH3_k127_2470660_5 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002112 290.0
PYH3_k127_2470660_6 Electron transfer flavoprotein domain K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001609 272.0
PYH3_k127_2470660_7 PFAM Electron transfer flavoprotein K03521 - - 0.000000000000000000000000000000000000000000000000000000001 210.0
PYH3_k127_2470660_8 COG1290 Cytochrome b subunit of the bc complex - - - 0.00000000000000000000000000000000000000000000000000000905 208.0
PYH3_k127_2470660_9 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.000000000000000000000000000000000000000001607 167.0
PYH3_k127_2476907_0 PFAM oxidoreductase, molybdopterin binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002656 249.0
PYH3_k127_2476907_1 Uncharacterised protein family (UPF0182) K09118 - - 0.0000000000001056 85.0
PYH3_k127_2476907_2 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.000000002826 63.0
PYH3_k127_2512028_0 COGs COG2141 Coenzyme F420-dependent N5 N10-methylene tetrahydromethanopterin reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 310.0
PYH3_k127_2512028_1 - - - - 0.000000000002818 69.0
PYH3_k127_2512028_2 HNH nucleases - - - 0.00001749 48.0
PYH3_k127_2512028_3 - - - - 0.0000355 51.0
PYH3_k127_2514268_0 Transketolase, central region K00162,K11381,K21417 - 1.2.4.1,1.2.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004318 356.0
PYH3_k127_2514268_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005241 338.0
PYH3_k127_2514268_10 ribonuclease inhibitor activity - - - 0.00000000000000000004985 94.0
PYH3_k127_2514268_2 3-beta hydroxysteroid dehydrogenase/isomerase family K01784,K02473,K03274 - 5.1.3.2,5.1.3.20,5.1.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008574 289.0
PYH3_k127_2514268_3 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627,K00658 - 2.3.1.12,2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000002448 256.0
PYH3_k127_2514268_4 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000003702 249.0
PYH3_k127_2514268_5 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 0.0000000000000000000000000000000000000000000000000000000000005165 218.0
PYH3_k127_2514268_6 PFAM carbohydrate kinase K00848,K00851,K00854,K00862 - 2.7.1.12,2.7.1.17,2.7.1.215,2.7.1.5 0.0000000000000000000000000000000000000000000000000005968 203.0
PYH3_k127_2514268_7 Belongs to the short-chain dehydrogenases reductases (SDR) family K03366 - 1.1.1.304,1.1.1.76 0.0000000000000000000000000000000000000000000000002345 188.0
PYH3_k127_2514268_8 Xylose isomerase-like TIM barrel K10709 - - 0.00000000000000000000000000000000000000000000006702 179.0
PYH3_k127_2514268_9 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000003475 168.0
PYH3_k127_2514784_0 Transketolase, pyrimidine binding domain K21417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005334 406.0
PYH3_k127_2514784_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001969 366.0
PYH3_k127_2514784_2 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 362.0
PYH3_k127_2514784_3 COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases K15510,K21835 - 1.1.98.2,1.1.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 298.0
PYH3_k127_2514784_4 of components of various dehydrogenase complexes K00627 - 2.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001709 289.0
PYH3_k127_2514784_5 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000002143 262.0
PYH3_k127_2514784_6 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000694 187.0
PYH3_k127_2514784_7 myo-inosose-2 dehydratase activity K03079 - 5.1.3.22 0.0000000000000000000001147 101.0
PYH3_k127_2514784_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000001471 90.0
PYH3_k127_2579157_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002708 439.0
PYH3_k127_2579157_1 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 349.0
PYH3_k127_2579157_2 PFAM Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001553 269.0
PYH3_k127_2579157_3 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000002323 184.0
PYH3_k127_2579157_4 Ribosome biogenesis protein, C-terminal K09140 - - 0.00000000000000000000000000000000000003442 151.0
PYH3_k127_2579157_5 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000009049 111.0
PYH3_k127_2579157_6 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.00000000001533 72.0
PYH3_k127_2627601_0 Threonine dehydratase K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002019 377.0
PYH3_k127_2627601_1 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007502 370.0
PYH3_k127_2627601_2 selenocysteine lyase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000186 249.0
PYH3_k127_2627601_3 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000003105 154.0
PYH3_k127_2627601_4 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016846,GO:0034641,GO:0043603,GO:0044237,GO:0051186,GO:0071704,GO:1901564 4.4.1.5 0.000000000000000000000004219 105.0
PYH3_k127_2670876_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006351 380.0
PYH3_k127_2670876_1 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 342.0
PYH3_k127_2670876_2 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 0.000000000000000000000000000000000000000000000000000000000000000004255 230.0
PYH3_k127_2670876_3 PFAM ParB domain protein nuclease - - - 0.000000000000000000000000000000000000000356 162.0
PYH3_k127_2670876_4 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.00000000000000000000000003528 115.0
PYH3_k127_2670876_5 PFAM Like-Sm ribonucleoprotein, core - - - 0.00000000000000000000000006644 112.0
PYH3_k127_2670876_6 PFAM Transcription factor CBF NF-Y histone domain protein - - - 0.00000000000001273 76.0
PYH3_k127_2670876_7 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000005499 77.0
PYH3_k127_2670876_8 Belongs to the eukaryotic ribosomal protein eS17 family K02962 - - 0.00000000001071 69.0
PYH3_k127_2670876_9 - - - - 0.000003296 50.0
PYH3_k127_2672211_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0016829,GO:0016846,GO:0019344,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0080146,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000003342 210.0
PYH3_k127_2672211_1 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000006933 199.0
PYH3_k127_2672211_2 Nitroreductase family - - - 0.000000000000000000000000000000000000001044 155.0
PYH3_k127_2672211_3 - - - - 0.0000000000002844 74.0
PYH3_k127_2681218_0 PFAM Prolyl oligopeptidase family - - - 3.012e-271 848.0
PYH3_k127_2681218_1 COG1529 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL homologs K00087 - 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002385 557.0
PYH3_k127_2681218_10 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000002715 207.0
PYH3_k127_2681218_11 - - - - 0.000000000000000000000000000000000000000000000000000001663 205.0
PYH3_k127_2681218_12 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000003906 189.0
PYH3_k127_2681218_13 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS CutS-like protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000456 177.0
PYH3_k127_2681218_14 methionine synthase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000155 180.0
PYH3_k127_2681218_15 Luciferase-like monooxygenase K04091 - 1.14.14.5 0.000000000000000000000000000000000000000003871 166.0
PYH3_k127_2681218_16 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000465 139.0
PYH3_k127_2681218_17 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000001504 135.0
PYH3_k127_2681218_18 - - - - 0.000000000000000000000000000000001259 140.0
PYH3_k127_2681218_19 - - - - 0.000000000000000000000000000086 122.0
PYH3_k127_2681218_2 COGs COG1331 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 422.0
PYH3_k127_2681218_20 PFAM regulatory protein TetR K03577,K18939 - - 0.0000000000000000000000008588 111.0
PYH3_k127_2681218_21 Transcriptional regulator K07729 - - 0.000000000000000000008504 94.0
PYH3_k127_2681218_22 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000001269 85.0
PYH3_k127_2681218_23 Rubrerythrin - - - 0.0000000000000231 80.0
PYH3_k127_2681218_24 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000001097 66.0
PYH3_k127_2681218_25 Bacterial transcription activator, effector binding domain - - - 0.0000000117 63.0
PYH3_k127_2681218_26 - - - - 0.0000003604 57.0
PYH3_k127_2681218_27 Protein of unknown function (DUF3796) - - - 0.0001238 49.0
PYH3_k127_2681218_28 deoxyhypusine monooxygenase activity - - - 0.0003508 50.0
PYH3_k127_2681218_29 GH3 auxin-responsive promoter - - - 0.0004583 52.0
PYH3_k127_2681218_3 Domain of unknown function (DUF362) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005386 362.0
PYH3_k127_2681218_30 PFAM thiamineS protein - - - 0.00055 46.0
PYH3_k127_2681218_4 PFAM Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002591 312.0
PYH3_k127_2681218_5 Formamidopyrimidine-DNA glycosylase N-terminal domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004085 301.0
PYH3_k127_2681218_6 Zinc-binding dehydrogenase K13953 - 1.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007022 275.0
PYH3_k127_2681218_7 Psort location Cytoplasmic, score - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001197 267.0
PYH3_k127_2681218_8 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001045 256.0
PYH3_k127_2681218_9 COG1319 Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM CutM homologs K00087,K03519 - 1.17.1.4,1.2.5.3 0.00000000000000000000000000000000000000000000000000000000002349 216.0
PYH3_k127_2686882_0 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003545 418.0
PYH3_k127_2686882_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 417.0
PYH3_k127_2686882_2 COG0657 Esterase lipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003118 362.0
PYH3_k127_2686882_3 oxidoreductases (related to aryl-alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000324 231.0
PYH3_k127_2686882_4 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.000000000000000000000000000000000003928 145.0
PYH3_k127_2686882_5 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000007537 115.0
PYH3_k127_2713309_0 aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003362 390.0
PYH3_k127_2713309_1 acetamidase formamidase K01455 - 3.5.1.49 0.000000000000000000000000000000000000000000000000000000000000000000001546 243.0
PYH3_k127_2713309_2 formylmethanofuran dehydrogenase, subunit E - - - 0.00000000000000001293 89.0
PYH3_k127_2796615_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 496.0
PYH3_k127_2796615_1 Penicillin amidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004789 484.0
PYH3_k127_2796615_2 actin actin family protein K18641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 443.0
PYH3_k127_2796615_3 Proline dehydrogenase K00318 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 262.0
PYH3_k127_2796615_4 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000007786 136.0
PYH3_k127_2796615_5 Belongs to the eukaryotic ribosomal protein eL38 family K02923 - - 0.00000000002421 65.0
PYH3_k127_2796615_6 TIGRFAM MoaD family protein K03636 - - 0.00000009259 56.0
PYH3_k127_2796615_7 Thioredoxin K03671 - - 0.0000001767 58.0
PYH3_k127_2796615_8 - - - - 0.0000168 55.0
PYH3_k127_2818287_0 Aminotransferase class-V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 414.0
PYH3_k127_2818287_1 arginine decarboxylase activity K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000292 248.0
PYH3_k127_2818287_10 MEDS: MEthanogen/methylotroph, DcmR Sensory domain - - - 0.000000000002625 74.0
PYH3_k127_2818287_2 cellular alkane metabolic process K16176 - 2.1.1.248 0.000000000000000000000000000000000000000000000000000000000001961 229.0
PYH3_k127_2818287_3 NifU-like N terminal domain K04488 - - 0.000000000000000000000000000000000000000000000000000009997 194.0
PYH3_k127_2818287_4 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000003673 188.0
PYH3_k127_2818287_5 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.00000000000000000000000000000000000000000000000158 181.0
PYH3_k127_2818287_6 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000138 174.0
PYH3_k127_2818287_7 Splits dipeptides with a prolyl in the C-terminal position and a nonpolar amino acid at the N-terminal position K01271 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.4.13.9 0.00000000000000000000000000000001502 134.0
PYH3_k127_2818287_8 Sugar (and other) transporter - - - 0.0000000000000000000000001388 120.0
PYH3_k127_2818287_9 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000004363 77.0
PYH3_k127_285606_0 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000003839 218.0
PYH3_k127_2868388_0 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002628 267.0
PYH3_k127_2868388_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000006729 235.0
PYH3_k127_2868388_2 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000001139 87.0
PYH3_k127_2868428_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00836 - 2.6.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 355.0
PYH3_k127_2868428_1 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002811 254.0
PYH3_k127_2868428_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.0001006 46.0
PYH3_k127_2868428_2 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000000000000000001433 205.0
PYH3_k127_2868428_3 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000001277 198.0
PYH3_k127_2868428_4 pyridoxamine 5-phosphate - - - 0.00000000000000000000000000000000000003099 147.0
PYH3_k127_2868428_5 - - - - 0.000000000000000000000000761 112.0
PYH3_k127_2868428_6 Protein of unknown function (DUF541) K09807 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000009404 106.0
PYH3_k127_2868428_7 COG1522 Transcriptional regulators - - - 0.000000000000000000007513 96.0
PYH3_k127_2868428_8 Rhomboid family K19225 - 3.4.21.105 0.0000000000000000232 87.0
PYH3_k127_2868428_9 transferase activity, transferring glycosyl groups - - - 0.000000003884 65.0
PYH3_k127_287472_0 DEAD DEAH box helicase domain protein K03724 - - 4.855e-247 794.0
PYH3_k127_287472_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 2.035e-211 672.0
PYH3_k127_287472_10 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 - - 0.0000000000000000000000000000000000000000121 156.0
PYH3_k127_287472_11 dipeptide transport K02035 - - 0.00000000000000000000000000000000000000005789 174.0
PYH3_k127_287472_12 PFAM ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000001056 126.0
PYH3_k127_287472_13 Belongs to the eukaryotic ribosomal protein eS6 family K02991 - - 0.0000000000000000000000000004775 121.0
PYH3_k127_287472_14 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.00000000000000000000000004553 109.0
PYH3_k127_287472_15 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.000000000000000000000009713 101.0
PYH3_k127_287472_16 Domain of unknown function (DUF2088) - - - 0.0000000000000000000003789 109.0
PYH3_k127_287472_17 Belongs to the UPF0218 family K09735 - - 0.000000000000000001257 90.0
PYH3_k127_287472_18 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000003749 82.0
PYH3_k127_287472_19 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.0000000000005784 74.0
PYH3_k127_287472_2 Histidine ammonia-lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000692 489.0
PYH3_k127_287472_20 - - - - 0.000000007411 69.0
PYH3_k127_287472_21 Lrp/AsnC ligand binding domain - - - 0.0002307 51.0
PYH3_k127_287472_3 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001433 379.0
PYH3_k127_287472_4 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 359.0
PYH3_k127_287472_5 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002809 252.0
PYH3_k127_287472_6 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
PYH3_k127_287472_7 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000001606 212.0
PYH3_k127_287472_8 Binding-protein-dependent transport system inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000001617 216.0
PYH3_k127_287472_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000004171 179.0
PYH3_k127_2897958_0 Beta-Casp domain K07041 - - 1.456e-214 684.0
PYH3_k127_2897958_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019774,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000973 223.0
PYH3_k127_2897958_2 Peptidyl-prolyl cis-trans K01802 - 5.2.1.8 0.000000000000000000000000000000000000000000000000006351 190.0
PYH3_k127_2897958_3 PFAM aminotransferase class V - GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000138 150.0
PYH3_k127_3023564_0 Phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 316.0
PYH3_k127_3023564_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000539 247.0
PYH3_k127_3028586_0 PFAM AAA ATPase central domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 420.0
PYH3_k127_3028586_1 Conserved protein implicated in secretion - - - 0.00000000000000000000000000000000000002993 151.0
PYH3_k127_3028586_2 Conserved protein implicated in secretion - - - 0.0000000000000000000000000000000006081 140.0
PYH3_k127_3028586_3 Conserved protein implicated in secretion - - - 0.000000000000000000000002865 110.0
PYH3_k127_3028586_4 - - - - 0.0000000000000000002157 97.0
PYH3_k127_3028586_5 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000003269 88.0
PYH3_k127_3028586_6 helix_turn_helix ASNC type - - - 0.00000000009958 71.0
PYH3_k127_3028586_7 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.00006939 52.0
PYH3_k127_3074560_0 pyruvate decarboxylase activity K04103 - 4.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 444.0
PYH3_k127_3074560_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007043 273.0
PYH3_k127_3074560_2 transcriptional - - - 0.000000000000000000000000000001307 123.0
PYH3_k127_3074560_3 Acyl-coenzyme A 6-aminopenicillanic acid acyl-transferase - - - 0.000000000004013 78.0
PYH3_k127_3074560_4 - - - - 0.000000004934 63.0
PYH3_k127_3138697_0 Thi4 family K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003666 431.0
PYH3_k127_3138697_1 Could be a 3Fe-4S cluster-containing protein K03855 - - 0.0000000000000000000000000004604 115.0
PYH3_k127_3138697_2 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.000000000000002108 79.0
PYH3_k127_3138697_3 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000001804 61.0
PYH3_k127_3138697_4 HNH nucleases - - - 0.00000002687 58.0
PYH3_k127_3138697_5 - - - - 0.00002357 51.0
PYH3_k127_3155684_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 1.281e-213 679.0
PYH3_k127_3155684_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.741e-195 620.0
PYH3_k127_3155684_10 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.0000000000000000000000000006112 116.0
PYH3_k127_3155684_11 Protein of unknown function (DUF424) K09148 - - 0.0000000000000001246 83.0
PYH3_k127_3155684_12 TIGRFAM MoaD family protein K03636 - - 0.00000000004264 67.0
PYH3_k127_3155684_2 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 456.0
PYH3_k127_3155684_3 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002764 435.0
PYH3_k127_3155684_4 Serine threonine protein kinase K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000003365 221.0
PYH3_k127_3155684_5 KH domain protein K06961 - - 0.000000000000000000000000000000000000000000000001441 179.0
PYH3_k127_3155684_6 PFAM transferase hexapeptide repeat containing protein - - - 0.0000000000000000000000000000000000000000001836 168.0
PYH3_k127_3155684_7 SMART phosphoesterase PHP domain protein - - - 0.00000000000000000000000000000000000005893 151.0
PYH3_k127_3155684_8 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.0000000000000000000000000000000003299 136.0
PYH3_k127_3155684_9 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000000000000000000001624 134.0
PYH3_k127_3195575_0 CO dehydrogenase flavoprotein C-terminal domain - - - 7.145e-203 653.0
PYH3_k127_3195575_1 COGs COG0076 Glutamate decarboxylase and related PLP-dependent protein K01634 - 4.1.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 567.0
PYH3_k127_3195575_2 xylulokinase activity K11216 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009372,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0042710,GO:0044010,GO:0044237,GO:0044764,GO:0051704,GO:0071518 2.7.1.189 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 547.0
PYH3_k127_3195575_3 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008766 510.0
PYH3_k127_3195575_4 Belongs to the FGGY kinase family K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 372.0
PYH3_k127_3195575_5 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 312.0
PYH3_k127_3195575_6 myo-inosose-2 dehydratase activity K01805 - 5.3.1.5 0.0000000000000000000000000000000001384 144.0
PYH3_k127_3195575_7 HAD-superfamily phosphatase, subfamily IIIC - - - 0.00000000000000000000000000000002809 134.0
PYH3_k127_3195575_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000005958 74.0
PYH3_k127_3195575_9 Transketolase, pyrimidine binding domain K21417 - - 0.0000001111 55.0
PYH3_k127_3223861_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000001924 123.0
PYH3_k127_3223861_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000006186 96.0
PYH3_k127_3246617_0 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000003812 232.0
PYH3_k127_3246617_1 Amino acid permease - - - 0.0000000000000000000000000000000000000000004133 177.0
PYH3_k127_3246617_2 - - - - 0.0000000000000000000000000000001271 129.0
PYH3_k127_3304189_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 - 2.7.7.7 5.682e-300 957.0
PYH3_k127_3304189_1 4-hydroxyphenylacetate 3-hydroxylase C terminal K14534 - 4.2.1.120,5.3.3.3 1.303e-220 692.0
PYH3_k127_3304189_10 FES K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000001724 179.0
PYH3_k127_3304189_11 COG0778 Nitroreductase K10678,K19285 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0010181,GO:0016491,GO:0016651,GO:0016657,GO:0032553,GO:0034567,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.5.1.38 0.000000000000000000000000000000006005 137.0
PYH3_k127_3304189_12 Guanylyltransferase that catalyzes the activation of 2- phospho-L-lactate (LP) as (2S)-lactyl-2-diphospho-5'-guanosine (LPPG), via the condensation of LP with GTP. Is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor K14941 - 2.7.7.68 0.0000000000000000000000000002157 122.0
PYH3_k127_3304189_13 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.00000000000000000000001924 106.0
PYH3_k127_3304189_14 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.0000000000000000000008442 98.0
PYH3_k127_3304189_15 Transcriptional regulator K11924 - - 0.000000000000007218 80.0
PYH3_k127_3304189_16 PFAM Transcription elongation factor Elf1 like - - - 0.000000000004275 70.0
PYH3_k127_3304189_18 Lrp/AsnC ligand binding domain - - - 0.00000294 52.0
PYH3_k127_3304189_19 Lrp/AsnC ligand binding domain - - - 0.00002144 51.0
PYH3_k127_3304189_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 551.0
PYH3_k127_3304189_20 - - - - 0.00006235 53.0
PYH3_k127_3304189_21 Protein of unknown function (DUF2721) - - - 0.0003206 49.0
PYH3_k127_3304189_22 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0004335 47.0
PYH3_k127_3304189_3 dihydrolipoamide dehydrogenase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 469.0
PYH3_k127_3304189_4 TIGRFAM LPPG domain K11212 - 2.7.8.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 363.0
PYH3_k127_3304189_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 356.0
PYH3_k127_3304189_6 carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 340.0
PYH3_k127_3304189_7 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 295.0
PYH3_k127_3304189_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03644,K03801 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0016740,GO:0016746,GO:0016747,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181,2.8.1.8 0.0000000000000000000000000000000000000000000000000000000001301 213.0
PYH3_k127_3304189_9 Hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000000000000000000000000000000008655 183.0
PYH3_k127_3330258_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 500.0
PYH3_k127_3330258_1 Iron-containing alcohol dehydrogenase K00001,K01714,K13954 - 1.1.1.1,4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003265 473.0
PYH3_k127_3330258_2 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002511 345.0
PYH3_k127_3330258_3 Antibiotic biosynthesis monooxygenase K11530 - 5.3.1.32 0.0000000000000000000000000000000000000000006031 159.0
PYH3_k127_3330923_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.02e-242 761.0
PYH3_k127_3330923_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 1.018e-212 677.0
PYH3_k127_3330923_10 HTH DNA binding domain - - - 0.00000001863 59.0
PYH3_k127_3330923_11 PFAM blue (type 1) copper domain protein K00368,K02638 - 1.7.2.1 0.0000001267 58.0
PYH3_k127_3330923_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 613.0
PYH3_k127_3330923_3 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003454 383.0
PYH3_k127_3330923_4 PFAM Thiolase K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 373.0
PYH3_k127_3330923_5 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000001114 188.0
PYH3_k127_3330923_6 Glyoxalase-like domain K05606 - 5.1.99.1 0.0000000000000000000000000000000000004422 143.0
PYH3_k127_3330923_7 - - - - 0.00000000000000000000000000000000008577 139.0
PYH3_k127_3330923_8 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000002805 124.0
PYH3_k127_3330923_9 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.000000000000000003256 91.0
PYH3_k127_3347247_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 5.102e-232 732.0
PYH3_k127_3347247_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 587.0
PYH3_k127_3347247_10 Chorismate mutase type II K00812 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000281 258.0
PYH3_k127_3347247_11 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000008126 182.0
PYH3_k127_3347247_12 TIGRFAM Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000002222 153.0
PYH3_k127_3347247_2 TIGRFAM acetolactate synthase, large subunit, biosynthetic type K01652 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005929 573.0
PYH3_k127_3347247_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 496.0
PYH3_k127_3347247_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 454.0
PYH3_k127_3347247_5 Isocitrate isopropylmalate dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 370.0
PYH3_k127_3347247_6 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 336.0
PYH3_k127_3347247_7 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 308.0
PYH3_k127_3347247_8 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 304.0
PYH3_k127_3347247_9 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000002682 262.0
PYH3_k127_3440561_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 3.228e-287 898.0
PYH3_k127_3440561_1 Pfam:DUF650 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 427.0
PYH3_k127_3440561_10 Domain of unknown function (DUF371) K09738 - - 0.00000000000000000000000000002926 121.0
PYH3_k127_3440561_11 Zn-ribbon RNA-binding protein with a function in translation K07580 - - 0.0000000000000000001014 89.0
PYH3_k127_3440561_12 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.00000000000009308 76.0
PYH3_k127_3440561_13 TIGRFAM geranylgeranyl reductase - - - 0.0000000000002213 73.0
PYH3_k127_3440561_14 - - - - 0.00000009385 57.0
PYH3_k127_3440561_15 - - - - 0.000001851 52.0
PYH3_k127_3440561_2 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into K04799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 399.0
PYH3_k127_3440561_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K13283 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 332.0
PYH3_k127_3440561_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000002105 268.0
PYH3_k127_3440561_5 Calcineurin-like phosphoesterase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001413 264.0
PYH3_k127_3440561_6 PFAM 5-formyltetrahydrofolate cyclo-ligase K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000003639 248.0
PYH3_k127_3440561_7 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000005049 240.0
PYH3_k127_3440561_8 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.000000000000000000000000000000000000000000000000000000004012 213.0
PYH3_k127_3440561_9 - - - - 0.0000000000000000000000000000000078 133.0
PYH3_k127_3694759_0 TIGRFAM TIGR00266 family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001141 251.0
PYH3_k127_3694759_1 Biotin-protein ligase, N terminal - - - 0.00000000000000000000000000000000000000000000007173 180.0
PYH3_k127_3694759_2 PFAM Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000001203 118.0
PYH3_k127_3694759_3 Mut7-C ubiquitin - - - 0.00000001928 60.0
PYH3_k127_3701393_0 Transposase for insertion sequence element - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003933 285.0
PYH3_k127_3713087_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K18020 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0043546,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363 1.2.5.3,1.2.99.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007174 483.0
PYH3_k127_3713087_1 Tetrahydromethanopterin S-methyltransferase MtrH subunit K00584 - 2.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000001592 257.0
PYH3_k127_3713087_2 Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000001478 239.0
PYH3_k127_3713087_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000001892 201.0
PYH3_k127_3713087_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.000000000000000000000004368 110.0
PYH3_k127_3713087_5 - - - - 0.00000000000000003571 89.0
PYH3_k127_3713087_6 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000004537 50.0
PYH3_k127_3713087_7 spore germination - - - 0.000004657 58.0
PYH3_k127_3761936_0 pyruvate phosphate dikinase K01007 - 2.7.9.2 2.943e-216 684.0
PYH3_k127_3761936_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 349.0
PYH3_k127_3763084_0 Fructose-bisphosphate aldolase class-II K01624 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 331.0
PYH3_k127_3763084_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005441 303.0
PYH3_k127_3763084_2 - - - - 0.00000000000000000000000000000000000000000000000000000001525 204.0
PYH3_k127_3763084_3 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000001447 170.0
PYH3_k127_3763084_4 ECF-type riboflavin transporter, S component - - - 0.0000000000000000000000000000000000004332 145.0
PYH3_k127_3763084_5 HIT domain K02503 - - 0.0000000000000000000000001152 111.0
PYH3_k127_3763084_6 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.000006696 52.0
PYH3_k127_3807972_0 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 331.0
PYH3_k127_3807972_1 Protein of unknown function (DUF354) K09726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001358 260.0
PYH3_k127_3807972_2 Trm112p-like protein - - - 0.0000000000000000000000004908 107.0
PYH3_k127_3807972_3 Protease prsW family - - - 0.00006841 50.0
PYH3_k127_3842984_0 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.000000000000000000000000000008989 131.0
PYH3_k127_3842984_1 Protein of unknown function (DUF998) - - - 0.0000003499 59.0
PYH3_k127_3844718_0 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 478.0
PYH3_k127_3844718_1 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00169,K00174 - 1.2.7.1,1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 337.0
PYH3_k127_3844718_2 - - - - 0.000000000000000000000000000001475 128.0
PYH3_k127_3844718_3 - - - - 0.0001645 51.0
PYH3_k127_3881856_0 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.00000000000000000000000000000000000000000000000000000003993 204.0
PYH3_k127_3881856_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.000000000000000000000000000000000000000000000000000007446 196.0
PYH3_k127_3881856_2 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.00000000000000000000000000000000000007902 148.0
PYH3_k127_3881856_3 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 GO:0000154,GO:0000494,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006325,GO:0006364,GO:0006396,GO:0006464,GO:0006479,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008213,GO:0008276,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0016074,GO:0016569,GO:0016570,GO:0016571,GO:0016740,GO:0016741,GO:0018364,GO:0019538,GO:0022613,GO:0031123,GO:0031126,GO:0031167,GO:0032259,GO:0033967,GO:0034470,GO:0034641,GO:0034660,GO:0034963,GO:0036009,GO:0036211,GO:0042054,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043414,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0046483,GO:0051276,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140096,GO:0140098,GO:0140102,GO:1901360,GO:1901363,GO:1901564,GO:1990258,GO:1990259 - 0.000000000000000000000000000000000006095 139.0
PYH3_k127_3881856_4 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 0.0000000000000000000000000004711 120.0
PYH3_k127_3881856_5 COG1522 Transcriptional regulators - - - 0.00000000000000000007224 93.0
PYH3_k127_3910045_0 PFAM TCP-1 cpn60 chaperonin family K22447 - - 8.202e-206 653.0
PYH3_k127_3910045_1 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 340.0
PYH3_k127_3910045_2 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000006895 181.0
PYH3_k127_3910045_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.00000000000000000000000000000000000000001251 155.0
PYH3_k127_3910045_4 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 GO:0003674,GO:0003824,GO:0004596,GO:0005575,GO:0005622,GO:0005623,GO:0006464,GO:0006473,GO:0006474,GO:0006807,GO:0008080,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0031248,GO:0031365,GO:0032991,GO:0034212,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051604,GO:0071704,GO:1901564,GO:1902493,GO:1902494,GO:1990234 2.3.1.128 0.000000000000000000000000000000000000001981 154.0
PYH3_k127_3910045_5 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.00000000000000000000000000000000000005148 149.0
PYH3_k127_3910045_6 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03014,K03055 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000002593 79.0
PYH3_k127_3910045_7 - K02339 - 2.7.7.7 0.00000000000006164 81.0
PYH3_k127_3943969_0 aldo keto reductase K18471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 373.0
PYH3_k127_3943969_1 ATPase component of various ABC-type transport systems with duplicated ATPase domain K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004297 382.0
PYH3_k127_3943969_10 converts alpha-aldose to the beta-anomer - - - 0.00000000000000000000000000000001051 139.0
PYH3_k127_3943969_11 phosphoserine phosphatase K01079 GO:0003674,GO:0003824,GO:0004647,GO:0004721,GO:0004722,GO:0005488,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016597,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0031406,GO:0036094,GO:0036211,GO:0040007,GO:0042578,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 3.1.3.3 0.0000000000001667 78.0
PYH3_k127_3943969_12 PFAM Cobalt transport protein K16785 - - 0.000000000103 72.0
PYH3_k127_3943969_2 FGGY family of carbohydrate kinases, N-terminal domain K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 301.0
PYH3_k127_3943969_3 Psort location Cytoplasmic, score 8.87 K00854 - 2.7.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000557 291.0
PYH3_k127_3943969_4 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000001199 251.0
PYH3_k127_3943969_5 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000003367 198.0
PYH3_k127_3943969_6 Phosphotriesterase family K07048 - - 0.000000000000000000000000000000000000000000000000002975 190.0
PYH3_k127_3943969_7 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000006601 184.0
PYH3_k127_3943969_8 4-Hydroxyphenylpyruvate dioxygenase K05606,K17315 - 5.1.99.1 0.000000000000000000000000000000000004749 142.0
PYH3_k127_3943969_9 Haem-degrading - - - 0.0000000000000000000000000000000001682 136.0
PYH3_k127_3960173_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000001742 245.0
PYH3_k127_3960173_1 - - - - 0.00000000000000000000000000000000000000002797 156.0
PYH3_k127_3960173_2 Sporulation protein YtfJ (Spore_YtfJ) - - - 0.0000000000000000000000003558 108.0
PYH3_k127_3960173_3 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000006732 80.0
PYH3_k127_3962168_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009006 276.0
PYH3_k127_3962168_1 Methyltransferase K15429 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000004552 236.0
PYH3_k127_3989157_0 DEAD DEAH box helicase domain protein K03724 - - 1.207e-200 659.0
PYH3_k127_3989157_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004419 373.0
PYH3_k127_3989157_10 PFAM peptidase M29, aminopeptidase II K19689 - - 0.0000000000000000000000000000001742 138.0
PYH3_k127_3989157_11 AAA domain K12614 GO:0000724,GO:0000725,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022402,GO:0030915,GO:0032991,GO:0033554,GO:0033676,GO:0034641,GO:0035861,GO:0042623,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0046483,GO:0050000,GO:0050896,GO:0051179,GO:0051304,GO:0051640,GO:0051641,GO:0051716,GO:0071139,GO:0071704,GO:0090304,GO:0090734,GO:0097159,GO:0097240,GO:0106068,GO:1901360,GO:1901363,GO:1902494,GO:1990234,GO:1990683 3.6.4.13 0.000000000000000001017 101.0
PYH3_k127_3989157_12 to Saccharomyces cerevisiae SMC5 (YOL034W) - GO:0000166,GO:0000725,GO:0000793,GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003697,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0006139,GO:0006259,GO:0006281,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007049,GO:0007059,GO:0008144,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022402,GO:0030554,GO:0030915,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034641,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051304,GO:0051716,GO:0071139,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0106068,GO:1901265,GO:1901360,GO:1901363,GO:1902494,GO:1990234 - 0.0000000000000006105 92.0
PYH3_k127_3989157_13 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.0000000000000103 79.0
PYH3_k127_3989157_14 COG1361 S-layer domain - - - 0.0000005566 61.0
PYH3_k127_3989157_15 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0003674,GO:0005488,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.000000696 55.0
PYH3_k127_3989157_16 H ACA RNA-protein complex K07569 - - 0.000001689 53.0
PYH3_k127_3989157_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001055 378.0
PYH3_k127_3989157_3 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001223 293.0
PYH3_k127_3989157_4 ABC-type cobalt transport system ATPase component K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000169 282.0
PYH3_k127_3989157_5 ATP-binding protein K16786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006584 254.0
PYH3_k127_3989157_6 PFAM sugar isomerase (SIS) K08094 - 5.3.1.27 0.000000000000000000000000000000000000000000000000000000000000000001629 232.0
PYH3_k127_3989157_7 metal-binding-domain 4Fe-4S-binding-domain containing ABC transporter K06927 - 6.3.1.14 0.000000000000000000000000000000000000000000000000000000000000389 218.0
PYH3_k127_3989157_8 PFAM phosphoesterase, RecJ domain protein - - - 0.0000000000000000000000000000000000000000000000004001 188.0
PYH3_k127_3989157_9 PFAM Cobalt transport protein K16785 - - 0.0000000000000000000000000000000000001321 151.0
PYH3_k127_3999411_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005528 544.0
PYH3_k127_3999411_1 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 - 2.4.2.57 0.00000000000000000000000000000000000000000000000001217 187.0
PYH3_k127_3999411_2 SnoaL-like domain K03088 - - 0.0000005972 53.0
PYH3_k127_4007319_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005414 565.0
PYH3_k127_4007319_1 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K10824,K12372,K13892 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0016020,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044464,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 3.6.3.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004531 394.0
PYH3_k127_4007319_2 oligopeptide dipeptide ABC transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 372.0
PYH3_k127_4007319_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 364.0
PYH3_k127_4007319_4 PFAM binding-protein-dependent transport systems inner membrane component K02034,K15586 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 347.0
PYH3_k127_4007319_5 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000001152 181.0
PYH3_k127_4007319_6 Hydantoin racemase K16841 - 5.1.99.3 0.00000000000003938 76.0
PYH3_k127_4012702_0 PFAM Aminotransferase class I and II K00639,K00652 - 2.3.1.29,2.3.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004649 426.0
PYH3_k127_4012702_1 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 403.0
PYH3_k127_4012702_10 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009014 243.0
PYH3_k127_4012702_11 Fumarase C-terminus K01676 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000009357 233.0
PYH3_k127_4012702_12 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000001425 229.0
PYH3_k127_4012702_13 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000002153 219.0
PYH3_k127_4012702_14 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000002664 201.0
PYH3_k127_4012702_15 Binds the lower part of the 30S subunit head K02982 - - 0.0000000000000000000000000000000000000000000000000000006967 200.0
PYH3_k127_4012702_16 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000009947 190.0
PYH3_k127_4012702_17 Putative RNA methyltransferase K09142 - - 0.00000000000000000000000000000000000000000000000004635 190.0
PYH3_k127_4012702_18 methylase K07446 - 2.1.1.213 0.00000000000000000000000000000000000000000000000009649 190.0
PYH3_k127_4012702_19 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000085 171.0
PYH3_k127_4012702_2 RmlD substrate binding domain K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 397.0
PYH3_k127_4012702_20 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000001061 174.0
PYH3_k127_4012702_21 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000001289 170.0
PYH3_k127_4012702_22 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000004072 146.0
PYH3_k127_4012702_23 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000005464 141.0
PYH3_k127_4012702_24 PFAM Thioredoxin K03671 - - 0.0000000000000000000000000000000306 129.0
PYH3_k127_4012702_25 membrane - - - 0.00000000000000000000000000000009859 135.0
PYH3_k127_4012702_26 PFAM phosphatidate cytidylyltransferase K18678 - 2.7.1.182 0.000000000000000000000000000001947 132.0
PYH3_k127_4012702_27 MoaE protein K03635 - 2.8.1.12 0.000000000000000000000000001113 117.0
PYH3_k127_4012702_28 ribosomal protein K02912 - - 0.00000000000000000000000006229 113.0
PYH3_k127_4012702_29 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000005618 108.0
PYH3_k127_4012702_3 hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 360.0
PYH3_k127_4012702_30 - - - - 0.0000000000000000000004754 101.0
PYH3_k127_4012702_31 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000008859 99.0
PYH3_k127_4012702_32 Peptidase C13 family - - - 0.000000000000000000001299 110.0
PYH3_k127_4012702_33 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000003419 99.0
PYH3_k127_4012702_34 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000006558 88.0
PYH3_k127_4012702_35 Binds 16S rRNA, required for the assembly of 30S particles K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008270,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046872,GO:0046914,GO:1990904 - 0.0000000000000001592 83.0
PYH3_k127_4012702_36 Oxidoreductase family, NAD-binding Rossmann fold K18855 - 1.1.1.374 0.0000000000000007126 89.0
PYH3_k127_4012702_37 Glycosyltransferase family 87 - - - 0.0000000000000007196 90.0
PYH3_k127_4012702_38 COG1522 Transcriptional regulators - - - 0.0000000000003451 73.0
PYH3_k127_4012702_39 Transcriptional regulator PadR-like family - - - 0.00000000000404 71.0
PYH3_k127_4012702_4 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 361.0
PYH3_k127_4012702_40 TIGRFAM peptidase S26B, signal peptidase K13280 - 3.4.21.89 0.000000003555 64.0
PYH3_k127_4012702_5 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009272 312.0
PYH3_k127_4012702_6 Belongs to the peptidase M50B family - GO:0003674,GO:0003824,GO:0003938,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006183,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005752 306.0
PYH3_k127_4012702_7 50S ribosomal protein L4 K02930 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002158 267.0
PYH3_k127_4012702_8 Belongs to the eukaryotic ribosomal protein eS4 family K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000007789 259.0
PYH3_k127_4012702_9 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000004585 254.0
PYH3_k127_4059673_0 Phenazine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 390.0
PYH3_k127_4059673_1 PFAM NmrA family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001579 286.0
PYH3_k127_4059673_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000004914 108.0
PYH3_k127_4059673_11 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.000000000000000000009395 98.0
PYH3_k127_4059673_12 COG0477 Permeases of the major facilitator superfamily - - - 0.0000000009267 70.0
PYH3_k127_4059673_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000003071 198.0
PYH3_k127_4059673_3 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000001378 189.0
PYH3_k127_4059673_4 spore germination K07790 - - 0.00000000000000000000000000000000000000000000000001634 192.0
PYH3_k127_4059673_5 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000007755 166.0
PYH3_k127_4059673_6 TIGRFAM RNA methyltransferase, TrmH family, group 1 - - - 0.00000000000000000000000000000000000000000134 166.0
PYH3_k127_4059673_7 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.0000000000000000000000000000000002567 139.0
PYH3_k127_4059673_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000002664 124.0
PYH3_k127_4059673_9 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.00000000000000000000000001122 113.0
PYH3_k127_4064164_0 TIGRFAM formylmethanofuran dehydrogenase subunit B K00201 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 381.0
PYH3_k127_4064164_1 DNA ligase (ATP) activity K01971 - 6.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000001434 246.0
PYH3_k127_4064164_10 Psort location Cytoplasmic, score K09707 - - 0.00000000000000000000000000000000000005338 145.0
PYH3_k127_4064164_11 SMART Elongator protein 3 MiaB NifB K22227 - - 0.00000000000000000000000000703 124.0
PYH3_k127_4064164_12 PFAM molydopterin dinucleotide-binding region K00203 - 1.2.7.12 0.0000000000000000000000006509 108.0
PYH3_k127_4064164_13 - - - - 0.0000000015 68.0
PYH3_k127_4064164_14 Integron-associated effector binding protein - - - 0.000000008828 63.0
PYH3_k127_4064164_15 Belongs to the ParB family K03497 - - 0.000000295 61.0
PYH3_k127_4064164_16 - - - - 0.0000006753 60.0
PYH3_k127_4064164_17 Cupin - - - 0.000001146 57.0
PYH3_k127_4064164_2 COGs COG1024 Enoyl-CoA hydratase carnithine racemase K15866 - 5.3.3.18 0.00000000000000000000000000000000000000000000000000000000000000001085 234.0
PYH3_k127_4064164_3 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000001262 229.0
PYH3_k127_4064164_4 DNA polymerase Ligase (LigD) K01971 - 6.5.1.1 0.00000000000000000000000000000000000000000000000000000001653 215.0
PYH3_k127_4064164_5 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000001024 204.0
PYH3_k127_4064164_6 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000009995 187.0
PYH3_k127_4064164_7 dna ligase K01971 - 6.5.1.1 0.0000000000000000000000000000000000000000000001849 185.0
PYH3_k127_4064164_8 Acetyltransferase (GNAT) domain K03824 - - 0.0000000000000000000000000000000000000000001611 166.0
PYH3_k127_4064164_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.0000000000000000000000000000000000000007007 158.0
PYH3_k127_4069255_0 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009315 337.0
PYH3_k127_4069255_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007141 248.0
PYH3_k127_4069255_2 Domain of unknown function (DUF4432) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002483 242.0
PYH3_k127_4069255_3 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000005967 132.0
PYH3_k127_4069255_4 COG1063 Threonine dehydrogenase and related Zn-dependent dehydrogenases - - - 0.00002855 51.0
PYH3_k127_4069255_5 SCP-2 sterol transfer family - - - 0.0004861 48.0
PYH3_k127_407045_0 CAAX protease self-immunity K07052 - - 0.00000000000000000000000000000000000000000000000000002961 198.0
PYH3_k127_407045_1 WD40-like Beta Propeller Repeat K03641 - - 0.000000000000000000000000000000000000001049 162.0
PYH3_k127_407045_2 myo-inosose-2 dehydratase activity - - - 0.000000000000000000000000000000007142 138.0
PYH3_k127_407045_4 - - - - 0.00001324 50.0
PYH3_k127_4141352_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 1.287e-239 754.0
PYH3_k127_4141352_1 4Fe-4S single cluster domain K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009484 341.0
PYH3_k127_4141352_10 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 - - 0.000000000000000000000005787 106.0
PYH3_k127_4141352_11 Belongs to the UPF0215 family K09120 - - 0.00000000000000001132 90.0
PYH3_k127_4141352_12 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000227 70.0
PYH3_k127_4141352_13 Ribonuclease III - - - 0.0000001146 59.0
PYH3_k127_4141352_2 Diphthamide K07561 - 2.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000004254 244.0
PYH3_k127_4141352_3 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.0000000000000000000000000000000000000000000000000000000000000545 226.0
PYH3_k127_4141352_4 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 - - 0.00000000000000000000000000000000000000000000000004889 187.0
PYH3_k127_4141352_5 Methyltransferase K07579 - - 0.00000000000000000000000000000000000000001582 160.0
PYH3_k127_4141352_6 Subtilase family - - - 0.000000000000000000000000000000002645 140.0
PYH3_k127_4141352_7 Thioredoxin K03671 - - 0.00000000000000000000000000004269 122.0
PYH3_k127_4141352_8 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000001689 122.0
PYH3_k127_4141352_9 - - - - 0.0000000000000000000000007571 109.0
PYH3_k127_4151489_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 446.0
PYH3_k127_4151489_1 PFAM Homoserine dehydrogenase K00003 - 1.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005391 333.0
PYH3_k127_4151489_10 Protein of unknown function DUF131 - - - 0.000000003532 62.0
PYH3_k127_4151489_11 Protein of unknown function DUF131 - - - 0.0005777 48.0
PYH3_k127_4151489_2 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 329.0
PYH3_k127_4151489_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000002149 242.0
PYH3_k127_4151489_4 amino acid - - - 0.00000000000000000000000000000000000000000000000000000001003 218.0
PYH3_k127_4151489_5 NhaP-type Na H and K H K03316 - - 0.000000000000000000000000000000000000000000000000008617 195.0
PYH3_k127_4151489_6 pyridoxamine 5'-phosphate K07005 - - 0.00000000000000000000000000000002453 132.0
PYH3_k127_4151489_7 PFAM NADPH-dependent FMN reductase - - - 0.000000000000000000000000000006271 128.0
PYH3_k127_4151489_8 - - - - 0.0000000000001108 77.0
PYH3_k127_4151489_9 NUDIX domain - - - 0.000000000007406 69.0
PYH3_k127_418038_0 dihydrodipicolinate reductase K03340,K21672 GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0047530,GO:0055114,GO:0071704,GO:1901564,GO:1901605 1.4.1.12,1.4.1.16,1.4.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 381.0
PYH3_k127_418038_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 313.0
PYH3_k127_418038_2 PFAM Xylose isomerase domain-containing protein TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005081 276.0
PYH3_k127_418038_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000004966 206.0
PYH3_k127_418038_4 PFAM B12 binding domain - - - 0.000000000000000000000000000000000000000000000000007331 188.0
PYH3_k127_418038_5 Creatinine amidohydrolase K01470 - 3.5.2.10 0.0000000000000000000000000000000001328 142.0
PYH3_k127_418038_6 COGs COG1082 Sugar phosphate isomerase epimerase - - - 0.000000000000056 82.0
PYH3_k127_418038_7 PFAM Uncharacterised BCR, COG1649 - - - 0.000213 46.0
PYH3_k127_41982_0 PFAM Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003224 434.0
PYH3_k127_41982_1 - - - - 0.000000000000000000000000005043 121.0
PYH3_k127_431548_0 Electron transfer flavoprotein K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 482.0
PYH3_k127_431548_1 FAD dependent oxidoreductase K00313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 380.0
PYH3_k127_431548_3 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03855 - - 0.000000000000000000000001262 105.0
PYH3_k127_433673_0 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000023 145.0
PYH3_k127_433673_1 peptidase - - - 0.00000000000000000000000000000000001799 145.0
PYH3_k127_433673_2 PFAM Rubrerythrin - - - 0.000000000000000000000000000000001466 134.0
PYH3_k127_433673_3 Belongs to the nitrite and sulfite reductase 4Fe-4S domain family K00362,K02192,K22405 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015044,GO:0016491,GO:0016730,GO:0016731,GO:0017144,GO:0022900,GO:0036094,GO:0043167,GO:0043168,GO:0044237,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0072592,GO:0097159,GO:1901265,GO:1901363 1.6.3.4,1.7.1.15 0.0000000036 62.0
PYH3_k127_433673_4 PFAM beta-lactamase domain protein - - - 0.00000003507 56.0
PYH3_k127_433673_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000002199 53.0
PYH3_k127_433673_6 Short C-terminal domain K08982 - - 0.00003864 50.0
PYH3_k127_4344397_0 adenosylhomocysteinase activity K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 557.0
PYH3_k127_4344397_1 PFAM Acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 556.0
PYH3_k127_4344397_2 AAA-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000392 493.0
PYH3_k127_4344397_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006022 479.0
PYH3_k127_4344397_4 Trypsin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003081 280.0
PYH3_k127_4344397_5 HpcH/HpaI aldolase/citrate lyase family K01630 - 4.1.2.20 0.000000000000000000000000000000000000000000000748 175.0
PYH3_k127_4344397_6 Peptidase family M48 - - - 0.0000000000000000002748 99.0
PYH3_k127_4344397_7 4Fe-4S double cluster binding domain - - - 0.000000000007362 75.0
PYH3_k127_4356804_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 568.0
PYH3_k127_4356804_1 Domain of unknown function (DUF4445) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 490.0
PYH3_k127_4356804_10 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000001094 177.0
PYH3_k127_4356804_11 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000001694 154.0
PYH3_k127_4356804_12 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000447 161.0
PYH3_k127_4356804_13 PFAM amidinotransferase K01478 - 3.5.3.6 0.000000000000000000000000000000001318 141.0
PYH3_k127_4356804_14 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000003342 127.0
PYH3_k127_4356804_15 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000002069 117.0
PYH3_k127_4356804_16 DNA helicase activity. It is involved in the biological process described with DNA replication initiation K02209 GO:0000003,GO:0000082,GO:0000278,GO:0000280,GO:0000712,GO:0000785,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006268,GO:0006275,GO:0006310,GO:0006323,GO:0006725,GO:0006807,GO:0006996,GO:0007049,GO:0007059,GO:0007127,GO:0007131,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010556,GO:0016043,GO:0019219,GO:0019222,GO:0022402,GO:0022414,GO:0030174,GO:0030261,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032392,GO:0032508,GO:0032991,GO:0034641,GO:0034645,GO:0035825,GO:0042023,GO:0042555,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044446,GO:0044464,GO:0044770,GO:0044772,GO:0044786,GO:0044843,GO:0045132,GO:0046483,GO:0048285,GO:0050789,GO:0050794,GO:0051052,GO:0051171,GO:0051276,GO:0051304,GO:0051307,GO:0051321,GO:0060255,GO:0061982,GO:0065007,GO:0070013,GO:0071103,GO:0071704,GO:0071840,GO:0080090,GO:0090304,GO:0090329,GO:0098813,GO:0140013,GO:1901360,GO:1901576,GO:1903046,GO:1903047,GO:2000112 3.6.4.12 0.00000000000000000000284 106.0
PYH3_k127_4356804_17 PAC2 family K07159 - - 0.00000000000000000003636 100.0
PYH3_k127_4356804_18 phosphatase activity K05967 - - 0.00000000000000005571 89.0
PYH3_k127_4356804_19 amino acid activation for nonribosomal peptide biosynthetic process - - - 0.000000000000002084 86.0
PYH3_k127_4356804_2 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 455.0
PYH3_k127_4356804_20 NHL repeat - - - 0.0000000000000614 83.0
PYH3_k127_4356804_21 Psort location CytoplasmicMembrane, score K16927 - - 0.00000000004438 72.0
PYH3_k127_4356804_22 RNA polymerase Rpb4 K03051 - 2.7.7.6 0.00000000007948 67.0
PYH3_k127_4356804_23 ATP-binding domain-containing protein - - - 0.000000003527 61.0
PYH3_k127_4356804_24 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000003294 55.0
PYH3_k127_4356804_25 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00004824 51.0
PYH3_k127_4356804_26 Domain of unknown function (DUF4129) - - - 0.0002199 52.0
PYH3_k127_4356804_3 Glycolate oxidase subunit (GlcD) K00104,K21836 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016614,GO:0036094,GO:0043167,GO:0043168,GO:0047809,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.1.3.15,1.1.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002471 416.0
PYH3_k127_4356804_4 ATPase associated with various cellular activities K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002204 385.0
PYH3_k127_4356804_5 Deoxyhypusine synthase K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000005502 251.0
PYH3_k127_4356804_6 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000001978 206.0
PYH3_k127_4356804_7 Protein of unknown function (DUF655) K07572 - - 0.00000000000000000000000000000000000000000000000000001961 194.0
PYH3_k127_4356804_8 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000405 196.0
PYH3_k127_4356804_9 PFAM PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000001277 185.0
PYH3_k127_4381127_0 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 GO:0003674,GO:0003824,GO:0003963,GO:0009975,GO:0016874,GO:0016886,GO:0140098 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004182 360.0
PYH3_k127_4381127_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000000001068 236.0
PYH3_k127_4381127_10 6-O-methylguanine DNA methyltransferase, DNA binding domain K00567 - 2.1.1.63 0.0000000000000001852 86.0
PYH3_k127_4381127_11 TIGRFAM cytidyltransferase-related domain K14656 - 2.7.7.2 0.000001625 53.0
PYH3_k127_4381127_12 Belongs to the UPF0248 family K09715 - - 0.0000168 51.0
PYH3_k127_4381127_13 aminopeptidase activity K19689 - - 0.0001665 45.0
PYH3_k127_4381127_2 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000001713 237.0
PYH3_k127_4381127_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000002113 208.0
PYH3_k127_4381127_4 PFAM S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000001056 204.0
PYH3_k127_4381127_5 Domain of unknown function DUF120 K07732 - 2.7.1.161 0.0000000000000000000000000000000000000000000000000132 188.0
PYH3_k127_4381127_6 nicotinamide-nucleotide adenylyltransferase activity K00952 - 2.7.7.1 0.0000000000000000000000000000000000000000000000003669 181.0
PYH3_k127_4381127_7 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.000000000000000000000000000000000000000001191 164.0
PYH3_k127_4381127_8 PFAM Translin K07477 - - 0.00000000000000000000000002583 116.0
PYH3_k127_4381127_9 Cytidylyltransferase-like K00980,K14656 - 2.7.7.2,2.7.7.39 0.0000000000000000000000001064 114.0
PYH3_k127_4506727_0 PFAM DNA polymerase, beta domain protein region K09717 - - 0.000000000000000000000000000000000000000000002826 178.0
PYH3_k127_4506727_1 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000007695 109.0
PYH3_k127_4586588_0 Flavin containing amine oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 346.0
PYH3_k127_4586588_1 TIGRFAM succinate dehydrogenase and fumarate reductase iron-sulfur protein K00240 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000001415 230.0
PYH3_k127_4604182_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 0.0 1262.0
PYH3_k127_4604182_1 PFAM amino acid permease-associated region K20265 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 558.0
PYH3_k127_4604182_10 AsnC family - - - 0.0002582 46.0
PYH3_k127_4604182_2 Acetyl-CoA hydrolase/transferase N-terminal domain K18122 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 387.0
PYH3_k127_4604182_3 PFAM photosystem I assembly BtpA K06971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 377.0
PYH3_k127_4604182_4 Penicillin V acylase and related amidases K01442 - 3.5.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 315.0
PYH3_k127_4604182_5 Oxidoreductase family, C-terminal alpha beta domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001221 273.0
PYH3_k127_4604182_6 Domain of unknown function (DUF4872) - - - 0.00000000000000000000000000000000000000000000000001293 193.0
PYH3_k127_4604182_7 cAMP biosynthetic process K01768,K02483 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000178 208.0
PYH3_k127_4604182_8 pfkB family carbohydrate kinase - - - 0.00000000000000000000638 103.0
PYH3_k127_4604182_9 Putative tRNA binding domain - - - 0.000000000000008515 75.0
PYH3_k127_4607814_0 PFAM ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 480.0
PYH3_k127_4607814_1 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 447.0
PYH3_k127_4607814_2 ABC transporter substrate-binding protein PnrA-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 365.0
PYH3_k127_4607814_3 aldehyde ferredoxin oxidoreductase activity K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001462 301.0
PYH3_k127_4607814_4 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 298.0
PYH3_k127_4607814_5 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005712 276.0
PYH3_k127_4607814_6 Psort location Cytoplasmic, score 8.87 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001346 242.0
PYH3_k127_4796264_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 492.0
PYH3_k127_4796264_1 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009867 331.0
PYH3_k127_4796264_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 329.0
PYH3_k127_4796264_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002072 244.0
PYH3_k127_4796264_4 OsmC-like protein - - - 0.0000000000000000000000000000000001087 138.0
PYH3_k127_4796264_5 Methyltransferase domain K02493 - 2.1.1.297 0.00000000000000000000000000046 121.0
PYH3_k127_4796264_6 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000001454 95.0
PYH3_k127_4796264_8 radical SAM domain protein K03639 - 4.1.99.22 0.000001792 50.0
PYH3_k127_4914881_0 PFAM Luciferase-like monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 308.0
PYH3_k127_4914881_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.0003345 45.0
PYH3_k127_4936686_0 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 369.0
PYH3_k127_4936686_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006592 314.0
PYH3_k127_4936686_2 FtsJ-like methyltransferase K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001956 289.0
PYH3_k127_4936686_3 8-oxoguanine DNA glycosylase, N-terminal domain K03660 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000001629 217.0
PYH3_k127_4936686_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000006598 168.0
PYH3_k127_4936686_5 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000006442 150.0
PYH3_k127_4936686_6 GDP-mannose mannosyl hydrolase activity K03207,K12944 - - 0.00000000000000000000000000000000006252 138.0
PYH3_k127_4936686_7 - - - - 0.0000000000001182 74.0
PYH3_k127_4936686_8 PIN domain of ribonuclease K07060 - - 0.0000000003624 63.0
PYH3_k127_4953411_0 ATPase involved in replication control, Cdc46 Mcm family K10726 - - 4.238e-224 732.0
PYH3_k127_4953411_1 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 601.0
PYH3_k127_4953411_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000537 418.0
PYH3_k127_4953411_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002724 380.0
PYH3_k127_4953411_4 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000002785 198.0
PYH3_k127_4953411_5 GINS complex protein K09723 - - 0.00000000000004108 79.0
PYH3_k127_4972612_0 Aspartate carbamoyltransferase K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 363.0
PYH3_k127_4972612_1 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.0000000000000000000000000000000000000000000005535 171.0
PYH3_k127_4972612_2 DNA polymerase Ligase (LigD) - - - 0.000000000000000000000000000000000000000000003917 166.0
PYH3_k127_4972612_3 - - - - 0.000000000000000000000000000006561 126.0
PYH3_k127_4972612_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0008150,GO:0015075,GO:0015399,GO:0015405,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022804,GO:0022853,GO:0022857,GO:0034220,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0051179,GO:0051234,GO:0055085,GO:0090662,GO:0098660,GO:0099131 - 0.000000001183 64.0
PYH3_k127_4972612_5 Hsp20/alpha crystallin family K13993 - - 0.0000000987 60.0
PYH3_k127_4982175_0 Belongs to the peptidase S16 family - - - 5.095e-244 777.0
PYH3_k127_4992902_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K13798 - 2.7.7.6 0.0 1306.0
PYH3_k127_4992902_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 2.979e-286 922.0
PYH3_k127_4992902_10 Branched-chain amino acid transport system / permease component K02057 - - 0.000000000000000000000000000000000000000000000000000000000000000008198 236.0
PYH3_k127_4992902_11 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.000000000000000000000000000000000000000000000000000000000001084 224.0
PYH3_k127_4992902_12 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000004576 207.0
PYH3_k127_4992902_13 Belongs to the complex I 20 kDa subunit family K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000003172 198.0
PYH3_k127_4992902_14 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000003025 196.0
PYH3_k127_4992902_15 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.00000000000000000000000000000000000000000000000005228 182.0
PYH3_k127_4992902_16 Bacterial phospho-glucose isomerase C-terminal SIS domain K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000003615 160.0
PYH3_k127_4992902_17 Participates in transcription termination K02600 - - 0.00000000000000000000000000000000000005027 147.0
PYH3_k127_4992902_18 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000002189 133.0
PYH3_k127_4992902_19 PFAM NADH dehydrogenase (ubiquinone), 30 kDa subunit K00332 - 1.6.5.3 0.00000000000000000000000000000009247 131.0
PYH3_k127_4992902_2 PFAM basic membrane lipoprotein K07335 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 528.0
PYH3_k127_4992902_20 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000000000000002467 111.0
PYH3_k127_4992902_21 Belongs to the eukaryotic ribosomal protein eL30 family K02908 - - 0.000000000000000000000003781 108.0
PYH3_k127_4992902_22 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.00000000000000000000001378 106.0
PYH3_k127_4992902_23 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000007737 96.0
PYH3_k127_4992902_24 DUF72 domain containing protein - - - 0.00000000000000002848 90.0
PYH3_k127_4992902_25 Thiamine-phosphate synthase K22206 - - 0.00000000478 62.0
PYH3_k127_4992902_26 Parallel beta-helix repeats - - - 0.0000006526 57.0
PYH3_k127_4992902_27 protein conserved in archaea K09723 - - 0.000002617 57.0
PYH3_k127_4992902_29 - - - - 0.000467 52.0
PYH3_k127_4992902_3 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004339 509.0
PYH3_k127_4992902_4 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003355 472.0
PYH3_k127_4992902_5 TIGRFAM anaerobic ribonucleoside-triphosphate reductase K21636 - 1.1.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 360.0
PYH3_k127_4992902_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 313.0
PYH3_k127_4992902_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002488 333.0
PYH3_k127_4992902_8 PFAM inner-membrane translocator K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 299.0
PYH3_k127_4992902_9 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000001612 259.0
PYH3_k127_4997016_0 PFAM aspartate ornithine carbamoyltransferase, Asp Orn-binding region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 417.0
PYH3_k127_4997016_1 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006611 304.0
PYH3_k127_4997016_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000022 272.0
PYH3_k127_4997016_3 ABC transporter (ATP-binding protein)-putative sodium extrusion ABC transporter K09697 - 3.6.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000002704 251.0
PYH3_k127_4997016_4 PFAM ABC-2 type transporter K09696 - - 0.000000000000000000000000000000000000000005579 169.0
PYH3_k127_4997016_5 Transport permease protein K01992 - - 0.00000000000000000000000000000000000001537 149.0
PYH3_k127_4997016_6 DHHA1 domain K07463 - - 0.000000000000000000000000000000007513 141.0
PYH3_k127_4997016_7 Sodium/hydrogen exchanger family K03316 - - 0.000000000000000000006794 100.0
PYH3_k127_4997016_8 Transcriptional regulator K11924 - - 0.00000001304 59.0
PYH3_k127_5016175_0 Monomethylamine methyltransferase MtmB K16176 - 2.1.1.248 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 440.0
PYH3_k127_5016175_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000954 216.0
PYH3_k127_5016175_2 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K14084 - - 0.0000000000000000000000000000000000000000000000006893 182.0
PYH3_k127_5016175_3 - - - - 0.00000000000000000000000615 110.0
PYH3_k127_5019842_0 Transketolase, pyrimidine binding domain K11381,K21416 - 1.2.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001613 612.0
PYH3_k127_5019842_1 Catalyzes the condensation of formaldehyde with tetrahydromethanopterin (H(4)MPT) to 5,10- methylenetetrahydromethanopterin K13812 - 4.1.2.43,4.2.1.147 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 469.0
PYH3_k127_5019842_10 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 337.0
PYH3_k127_5019842_11 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001951 328.0
PYH3_k127_5019842_12 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004225 320.0
PYH3_k127_5019842_13 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 304.0
PYH3_k127_5019842_14 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004868 312.0
PYH3_k127_5019842_15 TIGRFAM 2-hydroxy-3-oxopropionate reductase K00042 GO:0003674,GO:0003824,GO:0005975,GO:0006082,GO:0008150,GO:0008152,GO:0008679,GO:0009056,GO:0009987,GO:0016052,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0019392,GO:0019394,GO:0019577,GO:0019579,GO:0019580,GO:0019752,GO:0042737,GO:0042836,GO:0042838,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0046392,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 294.0
PYH3_k127_5019842_16 Enoyl-(Acyl carrier protein) reductase K00046,K00065 - 1.1.1.127,1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 291.0
PYH3_k127_5019842_17 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004734 299.0
PYH3_k127_5019842_18 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001297 290.0
PYH3_k127_5019842_19 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002592 269.0
PYH3_k127_5019842_2 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005514 408.0
PYH3_k127_5019842_20 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000004931 279.0
PYH3_k127_5019842_21 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000007404 266.0
PYH3_k127_5019842_22 Glucose dehydrogenase C-terminus - - - 0.000000000000000000000000000000000000000000000000000000000000000000002617 248.0
PYH3_k127_5019842_23 Oligosaccharyl transferase STT3 subunit K07151 - 2.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000007671 254.0
PYH3_k127_5019842_24 KR domain K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000002669 232.0
PYH3_k127_5019842_25 PFAM Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000004454 238.0
PYH3_k127_5019842_26 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000116 215.0
PYH3_k127_5019842_27 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000007918 208.0
PYH3_k127_5019842_28 Redoxin K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000001003 195.0
PYH3_k127_5019842_29 - - - - 0.000000000000000000000000000000000000000000000000000003502 199.0
PYH3_k127_5019842_3 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002306 409.0
PYH3_k127_5019842_30 Methionine synthase B12-binding module cap domain protein K00548,K14084 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000002773 197.0
PYH3_k127_5019842_31 - - - - 0.0000000000000000000000000000000000000000000000000004749 194.0
PYH3_k127_5019842_32 Translation initiation factor 2 K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000001999 192.0
PYH3_k127_5019842_33 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K14084 - - 0.000000000000000000000000000000000000000000000000008542 188.0
PYH3_k127_5019842_34 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000005975 184.0
PYH3_k127_5019842_35 enzyme involved in inositol metabolism K03337 - 5.3.1.30 0.00000000000000000000000000000000000000000002098 171.0
PYH3_k127_5019842_36 amino acid - - - 0.00000000000000000000000000000000000007546 161.0
PYH3_k127_5019842_37 Catalyzes the conversion of L-arabinose to L-ribulose K01804 - 5.3.1.4 0.0000000000000000000000000003624 130.0
PYH3_k127_5019842_38 binds to the 23S rRNA K02929 - - 0.00000000000000000000000000256 115.0
PYH3_k127_5019842_39 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000001976 91.0
PYH3_k127_5019842_4 Aminotransferase class-III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006736 398.0
PYH3_k127_5019842_40 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.000000000000007913 76.0
PYH3_k127_5019842_41 structural constituent of ribosome K02978 - - 0.0000000000003049 72.0
PYH3_k127_5019842_42 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.0000000000006978 73.0
PYH3_k127_5019842_43 PFAM Cupin - - - 0.00000009913 58.0
PYH3_k127_5019842_44 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 GO:0003674,GO:0003824,GO:0004462,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005777,GO:0005829,GO:0005886,GO:0006081,GO:0006082,GO:0006089,GO:0006950,GO:0006970,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009507,GO:0009526,GO:0009536,GO:0009628,GO:0009651,GO:0009941,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016151,GO:0016829,GO:0016846,GO:0019243,GO:0019752,GO:0019863,GO:0019865,GO:0031967,GO:0031975,GO:0032787,GO:0042180,GO:0042182,GO:0042221,GO:0042579,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0044877,GO:0046185,GO:0046686,GO:0046872,GO:0046914,GO:0050896,GO:0051596,GO:0061727,GO:0071704,GO:0071944,GO:1901575,GO:1901615 4.4.1.5 0.0000002186 59.0
PYH3_k127_5019842_45 SIS domain K13831 - 4.1.2.43,5.3.1.27 0.00002072 49.0
PYH3_k127_5019842_46 Luciferase-like monooxygenase K14728 - - 0.00003317 47.0
PYH3_k127_5019842_47 - - - - 0.0001368 47.0
PYH3_k127_5019842_5 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850,K21071 - 2.7.1.11,2.7.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001828 390.0
PYH3_k127_5019842_6 ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004112 362.0
PYH3_k127_5019842_7 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 355.0
PYH3_k127_5019842_8 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004435 338.0
PYH3_k127_5019842_9 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007927 339.0
PYH3_k127_5028774_0 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.000000000000000000000000000000000000000000000000000000003804 208.0
PYH3_k127_5028774_1 - - - - 0.000000000000000000000000004251 121.0
PYH3_k127_5028774_2 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000002553 72.0
PYH3_k127_5028774_3 dihydroorotate dehydrogenase activity - - - 0.0006139 49.0
PYH3_k127_5033677_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 379.0
PYH3_k127_5033677_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002489 289.0
PYH3_k127_5033677_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002735 281.0
PYH3_k127_5033677_3 TIGRFAM Shikimate kinase K00891 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004413,GO:0006082,GO:0006520,GO:0006555,GO:0006566,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009069,GO:0009086,GO:0009088,GO:0009092,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019202,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000001227 214.0
PYH3_k127_5033677_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.0000000000000000000000000000000000000000000000000000000001861 212.0
PYH3_k127_5061797_0 PFAM Transketolase domain protein K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004763 293.0
PYH3_k127_5061797_1 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000002433 179.0
PYH3_k127_5061797_2 Transketolase K00615 - 2.2.1.1 0.0000000000000000425 83.0
PYH3_k127_5061797_3 Universal stress protein family - - - 0.000000000003149 67.0
PYH3_k127_5082763_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 589.0
PYH3_k127_5082763_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 496.0
PYH3_k127_5082763_10 Spermidine putrescine-binding periplasmic protein K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000015 267.0
PYH3_k127_5082763_11 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007018 250.0
PYH3_k127_5082763_12 COG1177 ABC-type spermidine putrescine transport system, permease component II K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 237.0
PYH3_k127_5082763_13 AMMECR1 K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000003025 228.0
PYH3_k127_5082763_14 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.000000000000000000000000000000000000000000000000000000001152 216.0
PYH3_k127_5082763_15 Nitroreductase family K04719 - 1.13.11.79 0.000000000000000000000000000000000000000000000000000000006747 204.0
PYH3_k127_5082763_16 Cleaves both 3' and 5' ssDNA extremities of branched DNA structures K07503 - - 0.0000000000000000000000000000000000000000000000000002793 195.0
PYH3_k127_5082763_17 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000001465 196.0
PYH3_k127_5082763_18 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000004046 175.0
PYH3_k127_5082763_19 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.000000000000000000000000000000000000000002908 164.0
PYH3_k127_5082763_2 amino acid K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 391.0
PYH3_k127_5082763_20 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000001056 169.0
PYH3_k127_5082763_21 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000000000000001247 156.0
PYH3_k127_5082763_22 VIT family - - - 0.000000000000000000000000000000000000003137 159.0
PYH3_k127_5082763_23 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.00000000000000000000000000000008971 132.0
PYH3_k127_5082763_24 PFAM CBS domain containing protein - - - 0.000000000000000000000000000000271 130.0
PYH3_k127_5082763_25 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000003734 128.0
PYH3_k127_5082763_26 - - - - 0.000000000000000000000000005886 117.0
PYH3_k127_5082763_28 Domain of unknown function (DUF4342) - - - 0.00000000000005626 76.0
PYH3_k127_5082763_29 Peptidyl-prolyl cis-trans isomerase K01802,K03767,K03768,K07151 - 2.4.99.18,5.2.1.8 0.000000000002298 81.0
PYH3_k127_5082763_3 SMART zinc finger, RanBP2-type - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 377.0
PYH3_k127_5082763_30 PFAM 4Fe-4S binding domain K00338 - 1.6.5.3 0.0000000001528 64.0
PYH3_k127_5082763_31 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA - - - 0.0000000004742 69.0
PYH3_k127_5082763_32 Putative zinc- or iron-chelating domain - - - 0.0000000006438 64.0
PYH3_k127_5082763_33 - - - - 0.000000188 58.0
PYH3_k127_5082763_34 Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis K03816 GO:0003674,GO:0003824,GO:0006139,GO:0006166,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046128,GO:0046129,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.22 0.000001794 59.0
PYH3_k127_5082763_35 - - - - 0.00006094 49.0
PYH3_k127_5082763_36 - - - - 0.0004618 50.0
PYH3_k127_5082763_37 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0005102 43.0
PYH3_k127_5082763_4 Domain of unknown function (DUF814) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000383 392.0
PYH3_k127_5082763_5 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 355.0
PYH3_k127_5082763_6 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000044 342.0
PYH3_k127_5082763_7 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 332.0
PYH3_k127_5082763_8 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003803 304.0
PYH3_k127_5082763_9 Nucleotidyl transferase K00966,K16881 - 2.7.7.13,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003145 285.0
PYH3_k127_5092697_0 PFAM YHS domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004741 602.0
PYH3_k127_5092697_1 Alpha beta hydrolase - - - 0.00000000000000000000000000003354 122.0
PYH3_k127_5092697_2 TIGRFAM cysteine desulfurase family protein - - - 0.0000000000001963 76.0
PYH3_k127_5092697_3 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00034,K00059,K04708 - 1.1.1.100,1.1.1.102,1.1.1.47 0.0008996 43.0
PYH3_k127_5125211_0 serine-type peptidase activity K01278 - 3.4.14.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 570.0
PYH3_k127_5147570_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 371.0
PYH3_k127_5147570_1 Acyl-CoA dehydrogenase, N-terminal domain K04117 - - 0.000000000000000000000000000000000000000000000000000000000000000138 229.0
PYH3_k127_5147570_2 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.00009303 49.0
PYH3_k127_5197180_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 516.0
PYH3_k127_5197180_1 PFAM natural resistance-associated macrophage protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 473.0
PYH3_k127_5197180_10 PFAM Mov34 MPN PAD-1 family - - - 0.000000000000003133 81.0
PYH3_k127_5197180_11 - - - - 0.0000417 51.0
PYH3_k127_5197180_2 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 474.0
PYH3_k127_5197180_3 Putative modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 371.0
PYH3_k127_5197180_4 CBS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008988 299.0
PYH3_k127_5197180_5 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000813 223.0
PYH3_k127_5197180_6 Methylpurine-DNA glycosylase (MPG) K03652 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000002442 200.0
PYH3_k127_5197180_7 PFAM Glycosyl transferase family 2 K00721,K00786 - 2.4.1.83 0.0000000000000000000000000000000000000000000000001605 185.0
PYH3_k127_5197180_8 Catalyzes the transfer of a methyl group to L- homocysteine resulting in methionine formation. The physiological methyl donor is K00549 - 2.1.1.14 0.00000000000000000000000000000000000004472 155.0
PYH3_k127_5197180_9 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K03658,K07466 - 3.6.4.12 0.0000000000000000000000000000004811 127.0
PYH3_k127_5199000_0 alcohol dehydrogenase K00008 - 1.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006657 290.0
PYH3_k127_5199000_1 Trimethylamine methyltransferase K14083 - 2.1.1.250 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001021 290.0
PYH3_k127_5199000_2 metal-dependent hydrolase with the TIM-barrel fold K07048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002207 274.0
PYH3_k127_5199000_3 amino acid K03294 - - 0.0000000000000000000000000000000000000000001162 178.0
PYH3_k127_5199000_4 Succinyl-CoA ligase like flavodoxin domain K01905,K22224 - 6.2.1.13 0.000000000000000000000000000000000001878 141.0
PYH3_k127_5199000_5 PFAM SNARE associated Golgi protein - - - 0.000000000000000000006193 99.0
PYH3_k127_5302279_0 PFAM CoA-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003805 474.0
PYH3_k127_5302279_1 TIGRFAM hydrogenase expression formation protein HypE K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 377.0
PYH3_k127_5302279_2 PFAM Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000009305 239.0
PYH3_k127_5302279_3 Belongs to the RimK family K05827,K05844 - 6.3.2.43 0.000000000000000000000000000000000000000000000000000000000000005235 227.0
PYH3_k127_5302279_4 TIGRFAM Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000206 216.0
PYH3_k127_5302279_5 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000004513 162.0
PYH3_k127_5302279_6 DNA polymerase beta domain protein region K09717 - - 0.0000000000000000000000000000000000000001642 165.0
PYH3_k127_5302279_7 F420-0:Gamma-glutamyl ligase - - - 0.00000000000000000000000000000000001153 143.0
PYH3_k127_5302279_8 Fibronectin type III domain K03933 - - 0.00000000001423 74.0
PYH3_k127_5302279_9 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000002525 68.0
PYH3_k127_530720_0 Nucleotidyltransferase domain K07076 - - 0.00000000000000000000000000000000000000000000295 185.0
PYH3_k127_530720_1 - - - - 0.000000000000000000000000000000000000000001471 169.0
PYH3_k127_530720_2 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000001414 129.0
PYH3_k127_530720_3 phosphatidylinositol metabolic process - - - 0.00000000000000000000000000002571 132.0
PYH3_k127_530720_5 Protein of unknown function (DUF1349) - - - 0.000005479 60.0
PYH3_k127_530720_6 - - - - 0.00002449 54.0
PYH3_k127_5349590_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 8.827e-223 699.0
PYH3_k127_5349590_1 Aminotransferase class-III K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000004331 239.0
PYH3_k127_5349590_2 Coenzyme F420-reducing hydrogenase, gamma subunit K14128 - 1.8.98.5 0.00000000000000000000000000000000000003008 145.0
PYH3_k127_5349590_3 spore germination K00442,K03605,K04656,K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.0000000000000006957 84.0
PYH3_k127_5393490_0 Sulfatase K01130 - 3.1.6.1 0.0 1033.0
PYH3_k127_5393490_1 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 314.0
PYH3_k127_5393490_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000000000000000000000000000000000000000002749 169.0
PYH3_k127_5393490_3 Short repeat of unknown function (DUF308) - - - 0.00000000000000000000000000000000005208 139.0
PYH3_k127_5393490_4 membrane - - - 0.000002292 58.0
PYH3_k127_5476583_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 356.0
PYH3_k127_5476583_1 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K19591,K22491 - - 0.00000000000000000000000000000000000002424 148.0
PYH3_k127_5476583_2 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000002679 87.0
PYH3_k127_5490085_0 Involved in regulation of DNA replication K10725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006767 418.0
PYH3_k127_5490085_1 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 349.0
PYH3_k127_5490085_2 Protein of unknown function DUF116 K09729 - - 0.0000000000000000000000000000000000000000000000000000000008646 208.0
PYH3_k127_5490085_3 PFAM NUDIX hydrolase K01515 - 3.6.1.13 0.00000000000000000000000000000000000000001576 159.0
PYH3_k127_5490085_4 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000001802 156.0
PYH3_k127_5490085_5 Protein of unknown function DUF99 K09120 - - 0.000000000000000000000009157 109.0
PYH3_k127_5490085_6 - - - - 0.00000000005728 68.0
PYH3_k127_5490085_7 - - - - 0.00001639 54.0
PYH3_k127_5525266_0 aspartate-semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 435.0
PYH3_k127_5525266_1 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000003249 179.0
PYH3_k127_5525266_2 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000004662 164.0
PYH3_k127_5525266_3 Acetamidase/Formamidase family K01426 - 3.5.1.4 0.0000000000000002334 80.0
PYH3_k127_5525266_4 PFAM aspartate glutamate uridylate kinase K00928 - 2.7.2.4 0.000000004584 62.0
PYH3_k127_5557189_0 Protein of unknown function (DUF998) - - - 0.00000000000000000000000000000000001422 148.0
PYH3_k127_5557189_1 - - - - 0.000000000000000000000001256 111.0
PYH3_k127_5557189_2 CAAX protease self-immunity K07052 - - 0.0000000000004809 71.0
PYH3_k127_5590447_0 formate C-acetyltransferase glycine radical - - - 7.154e-224 719.0
PYH3_k127_5590447_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004988 316.0
PYH3_k127_5590447_10 antibiotic catabolic process K13277,K20276 - - 0.00001331 59.0
PYH3_k127_5590447_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 299.0
PYH3_k127_5590447_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007002 293.0
PYH3_k127_5590447_4 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000004078 271.0
PYH3_k127_5590447_5 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000003497 186.0
PYH3_k127_5590447_6 protein secretion by the type IV secretion system - - - 0.000000000000000000000000000000001147 151.0
PYH3_k127_5590447_7 RNA-binding protein contains TRAM domain - - - 0.000000000000000003419 85.0
PYH3_k127_5590447_8 Pyridoxamine 5'-phosphate oxidase K01768 - 4.6.1.1 0.000000000000005948 84.0
PYH3_k127_5657453_0 alpha-L-fucosidase K01206 - 3.2.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 533.0
PYH3_k127_5657453_1 PFAM carbohydrate kinase K00854 - 2.7.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 389.0
PYH3_k127_5657453_10 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000005034 198.0
PYH3_k127_5657453_11 - - - - 0.000000000000000000000000000000000000000000000000004821 190.0
PYH3_k127_5657453_12 amino acid - - - 0.0000000000000000000000000000000000000000000000009862 196.0
PYH3_k127_5657453_13 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000001635 134.0
PYH3_k127_5657453_14 Domain of unknown function (DUF4349) - - - 0.000000000000000000000000000003072 130.0
PYH3_k127_5657453_15 Catalyzes the dephosphorylation of 2-phosphoglycolate K22223 - 3.1.3.18 0.000000000000000000000004943 110.0
PYH3_k127_5657453_16 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03539 - 3.1.26.5 0.000000008146 65.0
PYH3_k127_5657453_17 phosphoserine phosphatase K01079 - 3.1.3.3 0.00000002762 63.0
PYH3_k127_5657453_18 PFAM Major Facilitator Superfamily - - - 0.00000003381 65.0
PYH3_k127_5657453_19 RNA binding K07581 - - 0.00005664 47.0
PYH3_k127_5657453_2 metallophosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 322.0
PYH3_k127_5657453_20 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.00007813 49.0
PYH3_k127_5657453_3 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 295.0
PYH3_k127_5657453_4 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005637 246.0
PYH3_k127_5657453_5 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0019773,GO:0032991,GO:0044424,GO:0044464,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000002503 245.0
PYH3_k127_5657453_6 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004062 243.0
PYH3_k127_5657453_7 TIGRFAM acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000001043 222.0
PYH3_k127_5657453_8 - - - - 0.000000000000000000000000000000000000000000000000000015 198.0
PYH3_k127_5657453_9 2-Nitropropane dioxygenase - - - 0.00000000000000000000000000000000000000000000000000007757 194.0
PYH3_k127_5945799_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.11e-244 766.0
PYH3_k127_5945799_1 glutamine synthetase K01915 - 6.3.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009061 373.0
PYH3_k127_5945799_2 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000001928 276.0
PYH3_k127_5945799_3 Belongs to the mandelate racemase muconate lactonizing enzyme family K19802 - 5.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000002969 266.0
PYH3_k127_5945799_4 creatinase K01262,K01271 - 3.4.11.9,3.4.13.9 0.0006012 50.0
PYH3_k127_5995948_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 4.245e-312 982.0
PYH3_k127_5995948_1 GTPase of K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 437.0
PYH3_k127_5995948_10 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.000000000000000000000000000000000000001598 160.0
PYH3_k127_5995948_11 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.0000000000000000000000000000000000001502 145.0
PYH3_k127_5995948_12 Peptidase C13 family - - - 0.0000000005978 71.0
PYH3_k127_5995948_13 RNA binding K07581 - - 0.0000000009469 65.0
PYH3_k127_5995948_14 Belongs to the eukaryotic ribosomal protein eL13 family K02873 - - 0.000002134 56.0
PYH3_k127_5995948_2 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009299 365.0
PYH3_k127_5995948_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37 K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 354.0
PYH3_k127_5995948_4 DHHA1 domain K07463 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002898 320.0
PYH3_k127_5995948_5 serine threonine protein kinase K08851 GO:0000408,GO:0002949,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.7.11.1 0.00000000000000000000000000000000000000000000000000000007731 203.0
PYH3_k127_5995948_6 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000000001944 186.0
PYH3_k127_5995948_7 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000008221 181.0
PYH3_k127_5995948_8 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035870,GO:0036222,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.00000000000000000000000000000000000000000183 162.0
PYH3_k127_5995948_9 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000002244 160.0
PYH3_k127_6065065_0 Beta-lactamase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 523.0
PYH3_k127_6065065_1 2-oxoacid dehydrogenases acyltransferase (catalytic domain) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000585 267.0
PYH3_k127_6065065_2 Protein of unknown function (DUF998) - - - 0.0000000000000000000000000000000000000001312 159.0
PYH3_k127_6065065_3 - - - - 0.000000000000000000000000000000000002938 141.0
PYH3_k127_6065065_4 pyridoxamine 5'-phosphate - - - 0.0000000000000001633 85.0
PYH3_k127_6065065_5 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000001388 76.0
PYH3_k127_6065065_7 - - - - 0.0003676 45.0
PYH3_k127_6152821_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000002326 272.0
PYH3_k127_6152821_1 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000002648 273.0
PYH3_k127_6152821_10 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.0000000000000000000000000004394 123.0
PYH3_k127_6152821_11 binding-protein-dependent transport systems inner membrane component - - - 0.000000000000000000003235 101.0
PYH3_k127_6152821_12 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000003809 92.0
PYH3_k127_6152821_13 Belongs to the UPF0201 family K09736 - - 0.000000000000000001058 92.0
PYH3_k127_6152821_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000001505 65.0
PYH3_k127_6152821_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000057 237.0
PYH3_k127_6152821_3 Ser thr protein kinase K07176 - - 0.000000000000000000000000000000000000000000000000000000152 203.0
PYH3_k127_6152821_4 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000000000768 180.0
PYH3_k127_6152821_5 Belongs to the UPF0200 family - - - 0.00000000000000000000000000000000000000000000007608 174.0
PYH3_k127_6152821_6 - - - - 0.0000000000000000000000000000000000000000000229 177.0
PYH3_k127_6152821_7 transport system permease component - - - 0.0000000000000000000000000000000000000001636 161.0
PYH3_k127_6152821_8 Succinylglutamate desuccinylase / Aspartoacylase family K06987 - - 0.0000000000000000000000000000000000003139 154.0
PYH3_k127_6152821_9 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000002437 133.0
PYH3_k127_6172973_0 Sulfatase K01130 - 3.1.6.1 0.0 1024.0
PYH3_k127_6172973_1 COG2015 Alkyl sulfatase and related hydrolases - - - 1.778e-271 844.0
PYH3_k127_6172973_2 Sulfate permease family K03321 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005814 313.0
PYH3_k127_6172973_3 Short repeat of unknown function (DUF308) - - - 0.0000000000000000000000000000000004722 136.0
PYH3_k127_6172973_4 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 0.000000261 53.0
PYH3_k127_6172973_5 membrane - - - 0.000001602 58.0
PYH3_k127_620246_0 Aconitase family (aconitate hydratase) K01681 - 4.2.1.3 1.738e-256 805.0
PYH3_k127_620246_1 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000003881 227.0
PYH3_k127_620246_2 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000006257 102.0
PYH3_k127_6220362_0 FAD dependent oxidoreductase K03388,K16885 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 3.489e-240 760.0
PYH3_k127_6220362_1 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239,K00244,K17363 - 1.3.5.1,1.3.5.4,1.3.99.33 1.111e-219 694.0
PYH3_k127_6220362_10 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000001727 171.0
PYH3_k127_6220362_11 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000009853 132.0
PYH3_k127_6220362_12 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.00000000000000000001554 95.0
PYH3_k127_6220362_2 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 462.0
PYH3_k127_6220362_3 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 358.0
PYH3_k127_6220362_4 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 337.0
PYH3_k127_6220362_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 306.0
PYH3_k127_6220362_6 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00175 - 1.2.7.1,1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 306.0
PYH3_k127_6220362_7 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001165 260.0
PYH3_k127_6220362_8 Protein of unknown function (DUF554) K07150 - - 0.000000000000000000000000000000000000000000000000000000000000005937 223.0
PYH3_k127_6220362_9 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000003628 186.0
PYH3_k127_6246513_0 Sulfatase K01130 - 3.1.6.1 0.0 1019.0
PYH3_k127_6251660_0 Protein of unknown function (DUF917) K09703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 384.0
PYH3_k127_6251660_1 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 324.0
PYH3_k127_6251660_2 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 299.0
PYH3_k127_6251660_3 Hydantoin racemase K16841 - 5.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003555 283.0
PYH3_k127_6251660_4 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003235 260.0
PYH3_k127_6251660_5 Hydantoin racemase K16841 - 5.1.99.3 0.000000000000000000000000000000000000000000000000002856 190.0
PYH3_k127_6251660_6 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000005116 145.0
PYH3_k127_6251660_7 Binding-protein-dependent transport system inner membrane component K02053 - - 0.000006327 51.0
PYH3_k127_6273212_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 580.0
PYH3_k127_6273212_1 Belongs to the HMG-CoA reductase family K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 530.0
PYH3_k127_6273212_10 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000003383 254.0
PYH3_k127_6273212_11 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000368 243.0
PYH3_k127_6273212_12 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000002298 213.0
PYH3_k127_6273212_13 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000001967 206.0
PYH3_k127_6273212_14 PFAM UbiA prenyltransferase K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000005135 188.0
PYH3_k127_6273212_15 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000001805 187.0
PYH3_k127_6273212_16 membrane K08979 - - 0.0000000000000000000000000000000000000000000001907 189.0
PYH3_k127_6273212_17 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.0000000000000000000000000000000000000000000009017 177.0
PYH3_k127_6273212_18 Belongs to the UPF0107 family K09128 - - 0.0000000000000000000000000000000000000004832 153.0
PYH3_k127_6273212_19 Acid phosphatase homologues K19302 - 3.6.1.27 0.0000000000000000000000000000000001305 144.0
PYH3_k127_6273212_2 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 467.0
PYH3_k127_6273212_20 Rieske-like [2Fe-2S] domain K05710,K14578 - - 0.00000000000000000002575 94.0
PYH3_k127_6273212_21 Ferric reductase like transmembrane component - - - 0.000000000000000007908 96.0
PYH3_k127_6273212_22 AraC-like ligand binding domain - - - 0.000000000000005314 79.0
PYH3_k127_6273212_23 Family 4 glycosyl hydrolase K07406 - 3.2.1.22 0.0000000000002434 72.0
PYH3_k127_6273212_24 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000004342 71.0
PYH3_k127_6273212_25 Thiamine pyrophosphate enzyme, central domain K01652,K16787 - 2.2.1.6 0.00000000001044 67.0
PYH3_k127_6273212_26 CBS domain - - - 0.000000001361 70.0
PYH3_k127_6273212_27 Belongs to the class-I aminoacyl-tRNA synthetase family K01874 - 6.1.1.10 0.0000003196 57.0
PYH3_k127_6273212_28 P-type ATPase K17686 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0042802,GO:0044464,GO:0071944 3.6.3.54 0.0000138 49.0
PYH3_k127_6273212_3 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004127 383.0
PYH3_k127_6273212_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 362.0
PYH3_k127_6273212_5 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 333.0
PYH3_k127_6273212_6 TIGRFAM UbiD family decarboxylase - GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016829,GO:0016830,GO:0016831,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 323.0
PYH3_k127_6273212_7 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 310.0
PYH3_k127_6273212_8 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 295.0
PYH3_k127_6273212_9 GHMP kinases C terminal K00869 - 2.7.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000001133 259.0
PYH3_k127_6280047_0 Protein of unknown function (DUF1116) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 478.0
PYH3_k127_6280047_1 CoA-ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001246 247.0
PYH3_k127_6280047_2 Membrane - - - 0.0000000000000855 74.0
PYH3_k127_6280047_3 Protein of unknown function (DUF2877) - - - 0.00000007528 64.0
PYH3_k127_6280450_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 0.0 1064.0
PYH3_k127_6280450_1 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000007317 254.0
PYH3_k127_6280450_2 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000001882 129.0
PYH3_k127_6285815_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004952 539.0
PYH3_k127_6285815_1 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis K04479 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 357.0
PYH3_k127_6285815_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001357 232.0
PYH3_k127_6285815_3 PFAM nucleic acid binding, OB-fold, tRNA helicase-type K07466 - - 0.000000000000000000000000000000000000000001503 177.0
PYH3_k127_6285815_4 amino acid-binding ACT domain protein K07103 - - 0.0000000000000000000000000000000000002777 147.0
PYH3_k127_6285815_5 Fructose-1-6-bisphosphatase, N-terminal domain K01092 GO:0003674,GO:0003824,GO:0005975,GO:0006020,GO:0006066,GO:0006793,GO:0006796,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0008934,GO:0009056,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019637,GO:0019751,GO:0023052,GO:0042578,GO:0043647,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0046164,GO:0046174,GO:0046434,GO:0046838,GO:0046855,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0052745,GO:0052834,GO:0065007,GO:0071545,GO:0071704,GO:1901575,GO:1901615,GO:1901616 3.1.3.25 0.00000000000000000000000000000000007478 143.0
PYH3_k127_6285815_6 peptidase U32 - - - 0.00000000000000000006856 91.0
PYH3_k127_6285815_7 arylsulfatase activity - - - 0.000000001 63.0
PYH3_k127_6285815_8 Thioredoxin - GO:0003674,GO:0003824,GO:0004791,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0016671,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0047134,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 - 0.00002978 52.0
PYH3_k127_6303601_0 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
PYH3_k127_6303601_1 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000000000000008832 166.0
PYH3_k127_6303601_2 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000001069 134.0
PYH3_k127_6475301_0 TIGRFAM Hopanoid biosynthesis associated radical SAM protein HpnJ K04034 - 1.21.98.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 336.0
PYH3_k127_6475301_1 Glycosyl transferase, family 2 - - - 0.00006996 53.0
PYH3_k127_6560842_0 DNA Topoisomerase I (eukaryota) K03163 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 422.0
PYH3_k127_6560842_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003594 369.0
PYH3_k127_6560842_10 helix_turn_helix ASNC type K03719 - - 0.0000000000000000002769 93.0
PYH3_k127_6560842_11 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide K01574 - 4.1.1.4 0.00000000003168 72.0
PYH3_k127_6560842_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 366.0
PYH3_k127_6560842_3 PFAM Metallophosphoesterase K07096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008778 314.0
PYH3_k127_6560842_4 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 GO:0003674,GO:0003824,GO:0004795,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008144,GO:0016829,GO:0016835,GO:0016838,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 294.0
PYH3_k127_6560842_5 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002922 296.0
PYH3_k127_6560842_6 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000004214 265.0
PYH3_k127_6560842_7 PFAM Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000007393 221.0
PYH3_k127_6560842_8 - - - - 0.000000000000000000000000000000000000000000001483 174.0
PYH3_k127_6560842_9 COG0006 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.00000000000000000000000000000001535 142.0
PYH3_k127_6564655_0 Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family K01486 GO:0003674,GO:0003824,GO:0006040,GO:0006044,GO:0006046,GO:0008150,GO:0008152,GO:0008448,GO:0009056,GO:0016787,GO:0016810,GO:0016811,GO:0019213,GO:0046348,GO:0071704,GO:1901071,GO:1901072,GO:1901135,GO:1901136,GO:1901575 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 473.0
PYH3_k127_6564655_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III - - - 0.0000000000000000000000000000000000000000000000000000000000000005659 232.0
PYH3_k127_6564655_2 PFAM Threonyl alanyl tRNA synthetase, SAD K07050 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000002716 227.0
PYH3_k127_6605508_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.145e-196 630.0
PYH3_k127_6605508_1 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 5.523e-196 622.0
PYH3_k127_6605508_10 TIGRFAM molybdenum ABC transporter, periplasmic molybdate-binding protein K02020 - - 0.000000000000000000000000000000000000000000000006519 177.0
PYH3_k127_6605508_11 pfam yhs - - - 0.000000000002317 70.0
PYH3_k127_6605508_12 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.000008388 56.0
PYH3_k127_6605508_13 Uroporphyrinogen decarboxylase (URO-D) - - - 0.0001086 45.0
PYH3_k127_6605508_2 C-terminal domain of alpha-glycerophosphate oxidase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 537.0
PYH3_k127_6605508_3 PFAM Radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 459.0
PYH3_k127_6605508_4 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004945 362.0
PYH3_k127_6605508_5 Asp Glu hydantoin racemase - - - 0.0000000000000000000000000000000000000000000000000000000000000003266 228.0
PYH3_k127_6605508_6 ATPases associated with a variety of cellular activities K02017,K15497 - 3.6.3.29,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000005266 235.0
PYH3_k127_6605508_7 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000006011 218.0
PYH3_k127_6605508_8 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000006078 213.0
PYH3_k127_6605508_9 DeoC/LacD family aldolase - - - 0.000000000000000000000000000000000000000000000000000005194 202.0
PYH3_k127_6638139_0 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000000000000000000000000000000009063 233.0
PYH3_k127_6638139_1 Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000001074 212.0
PYH3_k127_6638139_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000002234 190.0
PYH3_k127_6638139_3 Tellurite resistance protein TehB - - - 0.0000000000000000000009447 106.0
PYH3_k127_6638139_4 YoaP-like - - - 0.000000004772 64.0
PYH3_k127_6638139_5 Pyridoxamine 5'-phosphate oxidase like - - - 0.000004204 52.0
PYH3_k127_6638139_6 Pyridoxamine 5'-phosphate oxidase - - - 0.00002182 49.0
PYH3_k127_6641852_0 TIGRFAM proton-translocating NADH-quinone oxidoreductase, chain L K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002408 596.0
PYH3_k127_6641852_1 Iron-sulfur cluster-binding domain K06871 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 556.0
PYH3_k127_6641852_10 UbiA prenyltransferase family K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 297.0
PYH3_k127_6641852_11 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
PYH3_k127_6641852_12 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000706 278.0
PYH3_k127_6641852_13 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000674 277.0
PYH3_k127_6641852_14 NADH dehydrogenase K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002481 270.0
PYH3_k127_6641852_15 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000116 233.0
PYH3_k127_6641852_16 Sap, sulfolipid-1-addressing protein - - - 0.0000000000000000000000000000000000000000000000000000009841 199.0
PYH3_k127_6641852_17 Pyruvate kinase, alpha/beta domain K09126 - - 0.00000000000000000000000000000000000000000000000000008682 192.0
PYH3_k127_6641852_18 pyruvate synthase activity K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000001963 182.0
PYH3_k127_6641852_19 V-type ATPase 116kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000002365 186.0
PYH3_k127_6641852_2 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 GO:0000287,GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006740,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0016829,GO:0016830,GO:0016832,GO:0019203,GO:0019318,GO:0019319,GO:0019362,GO:0019637,GO:0034641,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0046364,GO:0046483,GO:0046496,GO:0046872,GO:0050308,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072524,GO:1901360,GO:1901564,GO:1901576 3.1.3.11,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 531.0
PYH3_k127_6641852_20 Phosphate uptake regulator - - - 0.00000000000000000000000000000000000000000001569 176.0
PYH3_k127_6641852_21 Glyoxalase-like domain K06996 - - 0.000000000000000000000000000000000000000144 153.0
PYH3_k127_6641852_22 - - - - 0.000000000000000000000000000000000000363 147.0
PYH3_k127_6641852_23 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.000000000000000000000000000000000001815 150.0
PYH3_k127_6641852_24 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K02201 - 2.7.7.3 0.000000000000000000000000000000004528 134.0
PYH3_k127_6641852_25 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000001459 138.0
PYH3_k127_6641852_26 VIT family - - - 0.00000000000000000000000000000002543 136.0
PYH3_k127_6641852_27 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate family K00171 - 1.2.7.1 0.0000000000000000000000000000009434 123.0
PYH3_k127_6641852_28 Putative tRNA binding domain K06878 - - 0.000000000000000000000000000003315 127.0
PYH3_k127_6641852_29 - - - - 0.00000000000000000000000000004399 126.0
PYH3_k127_6641852_3 plastoquinone (complex I) K00342,K12137,K12141 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000614 445.0
PYH3_k127_6641852_30 PGAP1-like protein - - - 0.0000000000000000000000000001004 118.0
PYH3_k127_6641852_31 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.000000000000000000000871 102.0
PYH3_k127_6641852_32 UPF0056 membrane protein K05595 - - 0.000000000000000000001474 103.0
PYH3_k127_6641852_33 NADH ubiquinone oxidoreductase subunit 11 or 4L (chain K) K00340 - 1.6.5.3 0.00000000000000000007464 92.0
PYH3_k127_6641852_34 PFAM NADH-ubiquinone plastoquinone oxidoreductase chain 3 K00330 - 1.6.5.3 0.0000000000000001417 84.0
PYH3_k127_6641852_35 Periplasmic copper-binding protein (NosD) - - - 0.0000000000000001914 89.0
PYH3_k127_6641852_36 transporter K07238,K11021,K16267 - - 0.0000000000000002583 88.0
PYH3_k127_6641852_37 - - - - 0.0000000000001897 76.0
PYH3_k127_6641852_38 F0F1-type ATP synthase, subunit c archaeal vacuolar-type H -ATPase, subunit K K02124 - - 0.0000000000007908 73.0
PYH3_k127_6641852_39 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.000000000005662 74.0
PYH3_k127_6641852_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 443.0
PYH3_k127_6641852_40 Domain of unknown function (DUF4382) - - - 0.0000007445 57.0
PYH3_k127_6641852_41 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.000001545 57.0
PYH3_k127_6641852_42 - - - - 0.00005258 49.0
PYH3_k127_6641852_43 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00007329 54.0
PYH3_k127_6641852_5 PFAM pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00169 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005049 420.0
PYH3_k127_6641852_6 NADH ubiquinone oxidoreductase subunit 2 (Chain N) K22169 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 412.0
PYH3_k127_6641852_7 Oxidoreductase family, NAD-binding Rossmann fold K10219 - 1.1.1.312 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000676 393.0
PYH3_k127_6641852_8 PFAM Thiamine pyrophosphate K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008304 362.0
PYH3_k127_6641852_9 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342,K05575 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007483 345.0
PYH3_k127_6689332_0 Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1- phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis K00757 - 2.4.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004001 275.0
PYH3_k127_6689332_1 ABC-type cobalt transport system ATPase component K16787 - - 0.000000000000000000000000000000000000000000000000000000000000000000000456 246.0
PYH3_k127_6689332_2 ATP-binding protein K16786 - - 0.0000000000000000000000000000000000000000000000000000000000000005173 230.0
PYH3_k127_6689332_3 Psort location CytoplasmicMembrane, score K16923 - - 0.000000000000000000000000000000001495 136.0
PYH3_k127_6689332_4 Cobalt transport protein K16785 - - 0.0000000000000000000000000001017 125.0
PYH3_k127_6689332_5 Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway K00852 - 2.7.1.15 0.00000000000000000000000002725 120.0
PYH3_k127_6689332_6 membrane - - - 0.000000000003067 74.0
PYH3_k127_6689332_7 Catalytic component of the COP9 signalosome (CSN) complex that acts as an regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunit of SCF-type E3 ubiquitin-protein ligase complexes K09613 GO:0000003,GO:0000338,GO:0000749,GO:0000754,GO:0000909,GO:0003006,GO:0003674,GO:0003824,GO:0004175,GO:0004222,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006464,GO:0006508,GO:0006807,GO:0007275,GO:0008150,GO:0008152,GO:0008180,GO:0008233,GO:0008234,GO:0008237,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009987,GO:0010033,GO:0010646,GO:0010893,GO:0016787,GO:0019216,GO:0019218,GO:0019222,GO:0019236,GO:0019538,GO:0019783,GO:0019784,GO:0019953,GO:0022414,GO:0023051,GO:0023058,GO:0030447,GO:0030448,GO:0030582,GO:0030584,GO:0031136,GO:0031137,GO:0031139,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032443,GO:0032446,GO:0032501,GO:0032502,GO:0032991,GO:0036211,GO:0040007,GO:0042221,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043900,GO:0043902,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0044703,GO:0045116,GO:0045834,GO:0045940,GO:0046889,GO:0046890,GO:0046999,GO:0048518,GO:0048522,GO:0048583,GO:0048608,GO:0048731,GO:0048856,GO:0050789,GO:0050794,GO:0050810,GO:0050896,GO:0051704,GO:0051716,GO:0061458,GO:0062012,GO:0062013,GO:0065007,GO:0070011,GO:0070452,GO:0070646,GO:0070647,GO:0070791,GO:0070887,GO:0071310,GO:0071444,GO:0071704,GO:0075259,GO:0080090,GO:0106118,GO:0106120,GO:0140096,GO:1901564,GO:1902930,GO:1902932,GO:2000241,GO:2000243 - 0.000001385 61.0
PYH3_k127_6689332_8 AsnC family K03718 - - 0.00007796 47.0
PYH3_k127_6788490_0 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 372.0
PYH3_k127_6788490_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K01735,K13829 - 2.7.1.71,4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 340.0
PYH3_k127_6788490_2 Transketolase, pyridine binding domain protein K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 289.0
PYH3_k127_6788490_3 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000042 135.0
PYH3_k127_6788490_4 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.00000000000000000000000142 112.0
PYH3_k127_679064_0 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007292 372.0
PYH3_k127_679064_1 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 341.0
PYH3_k127_679064_10 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000001312 70.0
PYH3_k127_679064_11 Maintenance of mitochondrial structure and function K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.000000001864 67.0
PYH3_k127_679064_12 Belongs to the UPF0200 family - - - 0.00000006263 54.0
PYH3_k127_679064_2 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 322.0
PYH3_k127_679064_3 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000004067 201.0
PYH3_k127_679064_4 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000002547 190.0
PYH3_k127_679064_5 Flavodoxin domain K00230 - 1.3.5.3 0.00000000000000000000000000000000000000000000003218 175.0
PYH3_k127_679064_6 flavodoxin nitric oxide synthase - - - 0.000000000000000000000000001115 118.0
PYH3_k127_679064_7 PFAM transposase IS116 IS110 IS902 family - - - 0.0000000000000000001808 93.0
PYH3_k127_679064_9 PFAM Dak phosphatase K05879 - 2.7.1.121 0.000000000006257 74.0
PYH3_k127_6792050_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000551 488.0
PYH3_k127_6792050_1 small GTP-binding protein K06944 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 407.0
PYH3_k127_6792050_2 Beta-galactosidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 364.0
PYH3_k127_6792050_3 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008944 348.0
PYH3_k127_6792050_4 peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 343.0
PYH3_k127_6792050_5 peptidase activity K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001134 307.0
PYH3_k127_6792050_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000001043 246.0
PYH3_k127_6792050_7 Formaldehyde-activating enzyme (Fae) K10713 - 4.2.1.147 0.0000000000000000000000000000000000000000000001065 186.0
PYH3_k127_6792050_8 PFAM low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.0000000000000000000000000000000001157 137.0
PYH3_k127_6792050_9 Flavodoxin - - - 0.000000000000000000008359 99.0
PYH3_k127_7018777_0 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 343.0
PYH3_k127_7018777_1 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.000000000000000000000000000000000002312 145.0
PYH3_k127_7036955_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 2.275e-263 836.0
PYH3_k127_7036955_1 S-adenosylmethionine synthetase (AdoMet synthetase) K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 507.0
PYH3_k127_7036955_10 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000009067 239.0
PYH3_k127_7036955_11 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000003139 240.0
PYH3_k127_7036955_12 Helix-turn-helix domain - - - 0.00000000000000000000000000000003608 132.0
PYH3_k127_7036955_13 CAAX protease self-immunity - - - 0.000000000000000000002071 108.0
PYH3_k127_7036955_14 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000007138 89.0
PYH3_k127_7036955_15 Belongs to the UPF0292 family - - - 0.000000000000002993 81.0
PYH3_k127_7036955_16 metalloendopeptidase activity - - - 0.000001522 55.0
PYH3_k127_7036955_2 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 470.0
PYH3_k127_7036955_3 GTPase of unknown function C-terminal K06942 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005807 458.0
PYH3_k127_7036955_4 TIGRFAM Glyceraldehyde-3-phosphate dehydrogenase, type I K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 442.0
PYH3_k127_7036955_5 Phenylalanyl-tRNA synthetase beta subunit K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001275 445.0
PYH3_k127_7036955_6 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 435.0
PYH3_k127_7036955_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 383.0
PYH3_k127_7036955_8 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005282 338.0
PYH3_k127_7036955_9 Protein of unknown function (DUF1512) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006442 321.0
PYH3_k127_704285_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 524.0
PYH3_k127_704285_1 Isochorismatase family - - - 0.0000000000000000000000000000000000000000004454 166.0
PYH3_k127_704285_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.0000004498 53.0
PYH3_k127_7098004_0 AIR synthase related protein, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008687 313.0
PYH3_k127_7098004_1 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007346 284.0
PYH3_k127_7098004_2 PFAM Coenzyme F420 hydrogenase dehydrogenase beta subunit K00441,K22174 - 1.1.98.4,1.12.98.1 0.00000000000000000000000000000000000000000000001449 186.0
PYH3_k127_7098004_3 COG2015 Alkyl sulfatase and related hydrolases - - - 0.0000000000000000000000000000000000008003 142.0
PYH3_k127_7165566_0 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000004397 150.0
PYH3_k127_7165566_1 PFAM Molybdopterin guanine dinucleotide synthesis protein B K06947 - - 0.00000000000000000000000000000000001088 151.0
PYH3_k127_7165566_2 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000001019 136.0
PYH3_k127_7165566_3 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000002919 105.0
PYH3_k127_7224571_0 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.000000000000000000000000000000000000000000000000000000000003275 218.0
PYH3_k127_7224571_1 Uncharacterised protein family UPF0066 - - - 0.000000000000000000000000000000001635 134.0
PYH3_k127_7224571_2 COG0433 Predicted ATPase K06915 - - 0.000000000000000002917 86.0
PYH3_k127_727112_0 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 611.0
PYH3_k127_727112_1 Dihydroorotate dehydrogenase, electron transfer subunit, iron-sulphur cluster binding domain K00528,K16951 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 352.0
PYH3_k127_727112_2 DEAD DEAH box helicase domain protein K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
PYH3_k127_727112_3 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000000000000000000006338 177.0
PYH3_k127_727112_4 - - - - 0.00000001334 62.0
PYH3_k127_728726_0 ERCC4 domain K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 615.0
PYH3_k127_728726_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003441 265.0
PYH3_k127_728726_2 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000005152 234.0
PYH3_k127_728726_3 phosphoesterase RecJ domain protein K07463 - - 0.000000000000000000000000000000000000000000000004443 184.0
PYH3_k127_728726_4 thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.00000000000000000000000000000000000000002542 159.0
PYH3_k127_728726_5 Belongs to the UPF0147 family K09721 - - 0.000000000000000000000003274 105.0
PYH3_k127_728726_6 PFAM Sjogrens syndrome scleroderma autoantigen 1 K07143 - - 0.000000000000129 75.0
PYH3_k127_7385772_0 Glycine radical enzyme that catalyzes the cleavage of a C-N bond in choline, producing trimethylamine (TMA) and acetaldehyde K00656,K20038 - 2.3.1.54,4.3.99.4 0.0 1201.0
PYH3_k127_7385772_1 PFAM ABC transporter related K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004856 419.0
PYH3_k127_7385772_10 KR domain K00065 - 1.1.1.127 0.00000000000000000000000000000000000000000000000000000000000006282 222.0
PYH3_k127_7385772_11 Binding-protein-dependent transport system inner membrane component K02025 - - 0.0000000000000000000000000000000000000000000000000000000002236 213.0
PYH3_k127_7385772_12 Putative TM nitroreductase - - - 0.00000000000000000000000000000000000000000009891 166.0
PYH3_k127_7385772_13 Alcohol dehydrogenase GroES domain protein K00004 - 1.1.1.303,1.1.1.4 0.0000000000000000000000000000000000000004666 158.0
PYH3_k127_7385772_14 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000000000000000000000000000002005 154.0
PYH3_k127_7385772_15 COG0508 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes K00627 - 2.3.1.12 0.000000000000000000000000000000000005328 139.0
PYH3_k127_7385772_16 Bacterial extracellular solute-binding protein K02027 - - 0.00000000000000000000000000000001882 143.0
PYH3_k127_7385772_17 Pyridoxamine 5'-phosphate - - - 0.0000000000000000000000000000001884 130.0
PYH3_k127_7385772_18 - - - - 0.0000000000000000000000224 107.0
PYH3_k127_7385772_19 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000007784 104.0
PYH3_k127_7385772_2 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007535 422.0
PYH3_k127_7385772_20 TIGRFAM C_GCAxxG_C_C family protein - - - 0.0000000000000000000006033 101.0
PYH3_k127_7385772_21 Leucyl aminopeptidase (Aminopeptidase t) K19689 - - 0.000000000000000002467 97.0
PYH3_k127_7385772_23 WD-40 repeat - - - 0.000007468 59.0
PYH3_k127_7385772_24 PRC-barrel domain - - - 0.00001178 51.0
PYH3_k127_7385772_25 - - - - 0.00005384 51.0
PYH3_k127_7385772_26 Universal stress protein - - - 0.00008068 48.0
PYH3_k127_7385772_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009274 394.0
PYH3_k127_7385772_4 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 342.0
PYH3_k127_7385772_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004661 277.0
PYH3_k127_7385772_6 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 - 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003503 278.0
PYH3_k127_7385772_7 Domain of unknown function (DUF2088) K22373 - 5.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000008052 267.0
PYH3_k127_7385772_8 UV damage endonuclease UvdE K13281 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001462 252.0
PYH3_k127_7385772_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000008253 231.0
PYH3_k127_7457919_0 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000004395 203.0
PYH3_k127_7457919_1 ATP-dependent DNA helicase K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000006233 203.0
PYH3_k127_7457919_2 - - - - 0.00000009774 59.0
PYH3_k127_7457919_3 - - - - 0.0000002191 54.0
PYH3_k127_7464030_0 Ribose-5-phosphate isomerase. Source PGD - - - 0.0000000000000000000000000000000000000000000000003163 183.0
PYH3_k127_7464030_1 COG1522 Transcriptional regulators - - - 0.0000000000000000000001346 105.0
PYH3_k127_7464030_2 Heavy-metal-associated domain K17686 GO:0000041,GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005623,GO:0005886,GO:0006810,GO:0006811,GO:0006812,GO:0006825,GO:0008150,GO:0015677,GO:0016020,GO:0030001,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0051179,GO:0051234,GO:0071944 3.6.3.54 0.00001261 49.0
PYH3_k127_7464030_3 - - - - 0.00004235 54.0
PYH3_k127_7497746_0 Belongs to the carbamoyltransferase HypF family K04656 - - 5.616e-211 679.0
PYH3_k127_7497746_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 9.323e-203 641.0
PYH3_k127_7497746_10 4-phosphoerythronate dehydrogenase activity K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000003802 216.0
PYH3_k127_7497746_11 Phosphoribosyl transferase domain K00759,K09685 - 2.4.2.7 0.000000000000000000000000000000000000000000000000000009329 198.0
PYH3_k127_7497746_12 PFAM SpoVT AbrB - - - 0.000000000000000000000000000000000000000000004298 177.0
PYH3_k127_7497746_13 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate family K00177 - 1.2.7.3 0.0000000000000000000000000000000000001807 148.0
PYH3_k127_7497746_14 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000002473 108.0
PYH3_k127_7497746_15 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000001753 99.0
PYH3_k127_7497746_16 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.0000000000000000000007461 102.0
PYH3_k127_7497746_17 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00176 - 1.2.7.3 0.00000000000001809 76.0
PYH3_k127_7497746_18 Transglutaminase-like superfamily - - - 0.0000000000009794 78.0
PYH3_k127_7497746_2 Aminotransferase K09758 - 4.1.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005947 560.0
PYH3_k127_7497746_3 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009383 457.0
PYH3_k127_7497746_4 PFAM hydrogenase formation HypD protein K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006225 451.0
PYH3_k127_7497746_5 Predicted Permease Membrane Region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004497 447.0
PYH3_k127_7497746_6 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 366.0
PYH3_k127_7497746_7 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007237 347.0
PYH3_k127_7497746_8 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003967 306.0
PYH3_k127_7497746_9 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006788 274.0
PYH3_k127_7516032_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 504.0
PYH3_k127_7516032_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883,K15526 GO:0000166,GO:0001871,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009059,GO:0009986,GO:0009987,GO:0010125,GO:0010126,GO:0010467,GO:0016020,GO:0016070,GO:0016137,GO:0016138,GO:0016874,GO:0016875,GO:0016879,GO:0016880,GO:0017076,GO:0019538,GO:0019752,GO:0030246,GO:0030247,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035446,GO:0035639,GO:0036094,GO:0040007,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659,GO:2001065 6.1.1.16,6.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 492.0
PYH3_k127_7516032_10 PFAM YbaK prolyl-tRNA synthetase associated region - - - 0.00000000000000000000004889 104.0
PYH3_k127_7516032_11 binds to the 23S rRNA K02921 - - 0.000000000000000000002119 99.0
PYH3_k127_7516032_12 Belongs to the UPF0218 family K09735 - - 0.000000000000000000002327 101.0
PYH3_k127_7516032_13 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000003749 82.0
PYH3_k127_7516032_14 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.0000000000000000403 82.0
PYH3_k127_7516032_15 methyltransferase MtaA CmuA family K01599 - 4.1.1.37 0.00000000000000009576 83.0
PYH3_k127_7516032_16 Fcf1 K07158 - - 0.0000000000000008313 82.0
PYH3_k127_7516032_17 KEOPS complex Pcc1-like subunit K09741 - - 0.0002948 47.0
PYH3_k127_7516032_2 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 307.0
PYH3_k127_7516032_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004897 286.0
PYH3_k127_7516032_4 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000001711 221.0
PYH3_k127_7516032_5 DNA-directed RNA polymerase K03049 - 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000003094 213.0
PYH3_k127_7516032_6 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000267 209.0
PYH3_k127_7516032_7 PFAM Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.000000000000000000000000000000000000000000000000000000004076 213.0
PYH3_k127_7516032_8 GlcNAc-PI de-N-acetylase - - - 0.00000000000000000000000000000000000000000000000000004622 196.0
PYH3_k127_7516032_9 PFAM peptidase M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000002466 198.0
PYH3_k127_7530862_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002025 277.0
PYH3_k127_7530862_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002492 265.0
PYH3_k127_7530862_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000003889 246.0
PYH3_k127_7530862_3 Uroporphyrinogen decarboxylase (URO-D) - - - 0.000000000000000698 90.0
PYH3_k127_7530862_4 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000709 68.0
PYH3_k127_7536404_0 TIGRFAM TIGR00266 family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004354 319.0
PYH3_k127_7536404_1 PFAM Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000005344 113.0
PYH3_k127_7567527_0 Belongs to the TCP-1 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 379.0
PYH3_k127_7567527_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.000000000000000000000000000000000000000000000000000000000000000000002643 239.0
PYH3_k127_7567527_2 PFAM NurA domain - - - 0.0000000000000000002249 100.0
PYH3_k127_7567527_4 Transposase IS116/IS110/IS902 family - - - 0.000007312 51.0
PYH3_k127_7609725_0 Carbon-nitrogen hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008764 268.0
PYH3_k127_7609725_1 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003167 265.0
PYH3_k127_7609725_2 Cytochrome b(N-terminal)/b6/petB K03887 - - 0.00000000000000000000000000000000000000000000000000002163 195.0
PYH3_k127_7609725_3 Beta-eliminating lyase K01667 - 4.1.99.1 0.0000000000000000000000000000000000000004551 150.0
PYH3_k127_7609725_4 - - - - 0.00000000000000000000000000000000000000296 159.0
PYH3_k127_7609725_5 PFAM Prenyltransferase squalene oxidase - - - 0.00000000000000000000000000007382 122.0
PYH3_k127_7609725_6 Rieske [2Fe-2S] domain K08355 - 1.20.2.1,1.20.9.1 0.00000000000000000000000003856 114.0
PYH3_k127_7609725_7 Cytochrome b subunit of the bc complex K00412,K15879 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000008694 110.0
PYH3_k127_7609725_8 - - - - 0.000000000000000003467 88.0
PYH3_k127_7642786_0 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.000000000000000000000000000000000000000000000000000000000000000000006049 241.0
PYH3_k127_7642786_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000001646 90.0
PYH3_k127_7642786_2 thiolester hydrolase activity K00627,K06889 - 2.3.1.12 0.0000000000008078 72.0
PYH3_k127_7642786_3 Domain of unknown function (DUF1893) - - - 0.0000000001835 64.0
PYH3_k127_7642786_4 RNA methylase - GO:0003674,GO:0003824,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0016278,GO:0016279,GO:0016740,GO:0016741,GO:0018022,GO:0018193,GO:0018205,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:0140096,GO:1901564 - 0.00009277 45.0
PYH3_k127_7792991_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007008 363.0
PYH3_k127_7792991_1 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004176 361.0
PYH3_k127_7792991_2 xanthine dehydrogenase activity K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000002825 239.0
PYH3_k127_7792991_3 2Fe-2S -binding domain K03518,K18022 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0044424,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540,GO:0055114 1.2.5.3,1.2.99.8 0.0000000000000000000000000000000000000000000000000001082 190.0
PYH3_k127_7830085_0 PFAM UBA THIF-type NAD FAD binding protein - - - 0.00000000000000000000000000006298 130.0
PYH3_k127_7830085_1 Belongs to the ubiquitin-conjugating enzyme family K04649 GO:0000209,GO:0000502,GO:0003674,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006950,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010033,GO:0010243,GO:0010498,GO:0016043,GO:0016050,GO:0016567,GO:0016740,GO:0019538,GO:0019787,GO:0019899,GO:0019941,GO:0030163,GO:0030433,GO:0031625,GO:0032446,GO:0032991,GO:0033554,GO:0034976,GO:0036211,GO:0036503,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044389,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051603,GO:0051716,GO:0061630,GO:0061631,GO:0061650,GO:0061659,GO:0070647,GO:0071704,GO:0071840,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1902494,GO:1905368,GO:1905369 2.3.2.23 0.000000004009 65.0
PYH3_k127_7872941_0 Iron-sulfur cluster-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 378.0
PYH3_k127_7872941_1 Spore germination protein K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004995 296.0
PYH3_k127_7872941_2 ATPases associated with a variety of cellular activities K09817 - - 0.0000000000000000000000000000000000000000000000000000000006147 209.0
PYH3_k127_7872941_3 ABC transporter permease K19976 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0010035,GO:0010038,GO:0010043,GO:0016020,GO:0042221,GO:0044464,GO:0050896,GO:0071944 - 0.00000000000000000000000000002694 128.0
PYH3_k127_7872941_4 - - - - 0.000000000001157 74.0
PYH3_k127_7887444_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 603.0
PYH3_k127_7887444_1 Dihydroxyacetone kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003655 349.0
PYH3_k127_7887444_2 Belongs to the Glu Leu Phe Val dehydrogenases family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007338 278.0
PYH3_k127_7887444_3 Dihydroxyacetone kinase K05879 - 2.7.1.121 0.0000000000000000000000000000000000000001079 158.0
PYH3_k127_7887444_4 Exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000000002384 148.0
PYH3_k127_7887444_5 ZPR1-related zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000008498 138.0
PYH3_k127_7887444_6 - K00960 - 2.7.7.6 0.00000000000000302 76.0
PYH3_k127_7887444_7 Family of unknown function (DUF1028) - - - 0.000000003827 60.0
PYH3_k127_7887444_8 Sec61beta family - - - 0.00000001092 58.0
PYH3_k127_7892804_0 Nickel-dependent hydrogenase - - - 6.548e-209 657.0
PYH3_k127_7892804_1 Aldo/keto reductase family K16950 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005771 526.0
PYH3_k127_7892804_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009948 390.0
PYH3_k127_7892804_3 coenzyme F420 hydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009195 389.0
PYH3_k127_7892804_4 Belongs to the UPF0282 family K07022 - - 0.0000000000000000000000000000000000000000000000000000000000000000004804 241.0
PYH3_k127_7892804_5 radical SAM domain protein K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000004356 229.0
PYH3_k127_7892804_6 cyclic nucleotide binding K10914 - - 0.0000000000000000000000000000000000000000000000000000001518 202.0
PYH3_k127_7892804_7 Hydrogenase maturation protease - - - 0.0000000000000000000000000000000000001684 146.0
PYH3_k127_7892804_8 Catalyzes a proton abstraction reaction that results in 2,5-elimination of pyruvate from 2-succinyl-5-enolpyruvyl-6- hydroxy-3-cyclohexene-1-carboxylate (SEPHCHC) and the formation of 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate (SHCHC) K08680 - 4.2.99.20 0.0000000000000000000000000001323 125.0
PYH3_k127_8004586_0 Sodium Bile acid symporter family K03325 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006444 461.0
PYH3_k127_8004586_1 Radical SAM K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 344.0
PYH3_k127_8004586_2 OsmC-like protein - - - 0.000000000000000000000000000000000000000000166 162.0
PYH3_k127_8004586_3 NOG31153 non supervised orthologous group - - - 0.00000000000000000000000000000000000001242 158.0
PYH3_k127_8004586_4 DGC domain - - - 0.000000000000000000000000000000000007913 140.0
PYH3_k127_8004586_5 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000001434 129.0
PYH3_k127_8004586_6 DGC domain - - - 0.000000000000000000000000003891 115.0
PYH3_k127_8004586_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.00000000000000000000000002524 121.0
PYH3_k127_8004586_8 regulatory protein, arsR K03892 - - 0.00000000000000003243 87.0
PYH3_k127_8004586_9 Lipoate-protein ligase K03800 - 6.3.1.20 0.00000000001198 75.0
PYH3_k127_8023602_0 peptide catabolic process K13722 - - 5.339e-241 767.0
PYH3_k127_8023602_1 P COG3119 Arylsulfatase A and related enzymes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 345.0
PYH3_k127_8023602_2 PFAM Cys Met metabolism K01739,K01760,K01761 - 2.5.1.48,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 323.0
PYH3_k127_8260993_0 TIGRFAM asparagine synthase (glutamine-hydrolyzing) K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 370.0
PYH3_k127_8260993_1 - - - - 0.00000000000000000000000000000000000000000000000001783 196.0
PYH3_k127_8260993_2 - - - - 0.000000000000000000000000000001082 134.0
PYH3_k127_8600751_0 metallophosphoesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000687 314.0
PYH3_k127_8600751_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000002405 215.0
PYH3_k127_8600751_2 amino acid - - - 0.00000000000000000000000000000000000001603 162.0
PYH3_k127_8600751_3 - - - - 0.000000000000000000000000002958 116.0
PYH3_k127_8600751_4 Luciferase-like monooxygenase K21835 - 1.1.98.5 0.00000001594 62.0
PYH3_k127_8607591_0 Catalyzes the reversible transfer of a formyl group from formylmethanofuran (formyl-MFR) to tetrahydromethanopterin (H(4)MPT) so as to produce 5-formyl tetrahydromethanopterin (5- formyl-H(4)MPT) and methanofuran (MFR) K00672 - 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002796 332.0
PYH3_k127_8607591_1 Catalyzes the oxidation of methylene-H(4)MPT to methenyl-H(4)MPT( ) K00319 - 1.5.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 315.0
PYH3_k127_8610851_0 PFAM Chaperonin Cpn60 TCP-1 K22447 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002646 580.0
PYH3_k127_8610851_1 ABC transporter K02056 - 3.6.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001704 480.0
PYH3_k127_8610851_10 ABC-type transport system, periplasmic component surface lipoprotein K02058,K07335 - - 0.00000000000000000000000000000000000000000004671 175.0
PYH3_k127_8610851_11 PFAM ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000004905 159.0
PYH3_k127_8610851_12 Universal stress protein - - - 0.000000000000000000000001799 108.0
PYH3_k127_8610851_13 ABC-2 type transporter - - - 0.00000000000000001202 93.0
PYH3_k127_8610851_14 glycolate biosynthetic process - - - 0.00000000000000003094 90.0
PYH3_k127_8610851_15 Archaeal transcriptional regulator TrmB - - - 0.000000001022 68.0
PYH3_k127_8610851_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 411.0
PYH3_k127_8610851_3 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007524 367.0
PYH3_k127_8610851_4 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 364.0
PYH3_k127_8610851_5 aspartate ornithine carbamoyltransferase, carbamoyl-P binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 364.0
PYH3_k127_8610851_6 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 336.0
PYH3_k127_8610851_7 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009423 256.0
PYH3_k127_8610851_8 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000279 242.0
PYH3_k127_8610851_9 Ribosomal protein L11 methyltransferase (PrmA) K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000002215 217.0
PYH3_k127_861531_0 Sulfate permease K03321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000803 470.0
PYH3_k127_861531_1 COG3547 Transposase and inactivated derivatives - - - 0.000000000002621 76.0
PYH3_k127_861531_2 Major facilitator superfamily - - - 0.0000001429 64.0
PYH3_k127_8639544_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1041.0
PYH3_k127_8639544_1 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005356 464.0
PYH3_k127_8639544_10 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000001359 188.0
PYH3_k127_8639544_11 glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity K00134,K00150,K03340 - 1.2.1.12,1.2.1.59,1.4.1.16 0.00000000000000000000000000000000000000000000007796 172.0
PYH3_k127_8639544_12 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000185 174.0
PYH3_k127_8639544_13 TOBE domain - - - 0.000000000000000000002311 94.0
PYH3_k127_8639544_14 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.00000000000000000000427 104.0
PYH3_k127_8639544_2 l-lactate permease K03303 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 383.0
PYH3_k127_8639544_3 Peptidase M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 327.0
PYH3_k127_8639544_4 PFAM Major facilitator superfamily MFS-1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000345 280.0
PYH3_k127_8639544_5 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000002519 275.0
PYH3_k127_8639544_6 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001437 268.0
PYH3_k127_8639544_7 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000001693 216.0
PYH3_k127_8639544_8 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000026 203.0
PYH3_k127_8639544_9 PBP superfamily domain K03750,K07219 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000004722 207.0
PYH3_k127_8688697_0 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006403 327.0
PYH3_k127_8688697_1 Low molecular weight phosphotyrosine protein phosphatase K01104,K20201 - 3.1.3.48,3.9.1.2 0.000000000000000000003563 100.0
PYH3_k127_8688697_2 Cupin 2, conserved barrel domain protein - - - 0.0001951 44.0
PYH3_k127_8705080_0 Belongs to the ABC transporter superfamily K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003354 394.0
PYH3_k127_8705080_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 361.0
PYH3_k127_8705080_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004792 353.0
PYH3_k127_8705080_3 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008366 298.0
PYH3_k127_8705080_4 PFAM Histone deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 288.0
PYH3_k127_8705080_5 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 291.0
PYH3_k127_8705080_6 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000001558 166.0
PYH3_k127_8728635_0 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001455 374.0
PYH3_k127_8728635_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 357.0
PYH3_k127_8728635_10 PEP-utilising enzyme, mobile domain - - - 0.0000000000000002949 84.0
PYH3_k127_8728635_11 Protein of unknown function DUF47 K07220 - - 0.00000000007459 71.0
PYH3_k127_8728635_12 PFAM 4Fe-4S ferredoxin - - - 0.000000001351 61.0
PYH3_k127_8728635_2 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000535 305.0
PYH3_k127_8728635_3 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001417 291.0
PYH3_k127_8728635_4 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003224 286.0
PYH3_k127_8728635_5 ATPases associated with a variety of cellular activities K10112,K17240 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003278 268.0
PYH3_k127_8728635_6 - - - - 0.0000000000000000000000000000007982 134.0
PYH3_k127_8728635_7 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000006391 116.0
PYH3_k127_8728635_8 PEP-utilising enzyme, mobile domain - - - 0.000000000000000000008476 105.0
PYH3_k127_8728635_9 GIY-YIG catalytic domain K07461 - - 0.00000000000000006382 83.0
PYH3_k127_8730523_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.847e-200 646.0
PYH3_k127_8730523_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 598.0
PYH3_k127_8730523_2 TGS domain K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008257 315.0
PYH3_k127_8730523_3 tRNA intron endonuclease, N-terminal domain K01170 - 4.6.1.16 0.00000000000000000000000000000000000000000000000000002253 195.0
PYH3_k127_8730523_4 Belongs to the SUI1 family K03113 - - 0.00000000000000000000000000000235 122.0
PYH3_k127_8730523_5 PFAM Uncharacterised protein family (UPF0153) K06940 - - 0.00000000001237 72.0
PYH3_k127_8730523_6 Subtilase family - - - 0.0000000000535 76.0
PYH3_k127_8730523_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03059 - 2.7.7.6 0.000000002929 60.0
PYH3_k127_8730523_8 - - - - 0.0005888 46.0
PYH3_k127_8730523_9 Protein of unknown function DUF47 K07220 - - 0.0007093 49.0
PYH3_k127_8813077_0 AAA-like domain K06915 - - 0.0000000000000000000000000000000000000000000000000000000000000000000585 254.0
PYH3_k127_8813077_1 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000134 166.0
PYH3_k127_8829564_0 DNA polymerase K02319 - 2.7.7.7 1.633e-242 777.0
PYH3_k127_8829564_1 F420-0:Gamma-glutamyl ligase K12234 - 6.3.2.31,6.3.2.34 0.0000000000000000000000000000000000000000000000000000000000000000000000005666 256.0
PYH3_k127_8829564_10 PFAM CopG domain protein DNA-binding domain protein - - - 0.000000000002538 68.0
PYH3_k127_8829564_11 S25 ribosomal protein K02975 - - 0.00000001294 60.0
PYH3_k127_8829564_12 - - - - 0.000005058 57.0
PYH3_k127_8829564_13 Peptidase S8 K13277 - - 0.00001772 56.0
PYH3_k127_8829564_2 Glycosyl transferase family 21 - - - 0.0000000000000000000000000000000000000000000000000000000000000000002637 246.0
PYH3_k127_8829564_3 Belongs to the arginase family K01480 - 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000005231 221.0
PYH3_k127_8829564_4 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.00000000000000000000000000000000000000000000000000000000001828 214.0
PYH3_k127_8829564_5 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000008831 194.0
PYH3_k127_8829564_6 Orotidine 5'-phosphate decarboxylase / HUMPS family K01591 - 4.1.1.23 0.0000000000000000000000000000000000001936 150.0
PYH3_k127_8829564_7 Glycosyltransferase like family 2 K00721 - 2.4.1.83 0.000000000000000000000002477 113.0
PYH3_k127_8829564_8 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000001599 100.0
PYH3_k127_8829564_9 - K09143 - - 0.000000000000000001065 90.0
PYH3_k127_8901353_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002613 489.0
PYH3_k127_8901353_1 Staygreen protein K22013 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006787,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009536,GO:0009579,GO:0009892,GO:0009894,GO:0009895,GO:0009987,GO:0010271,GO:0015994,GO:0015996,GO:0016020,GO:0019222,GO:0019439,GO:0031323,GO:0031324,GO:0031329,GO:0031330,GO:0031976,GO:0031984,GO:0033013,GO:0033015,GO:0034357,GO:0034641,GO:0042440,GO:0042651,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044248,GO:0044270,GO:0044422,GO:0044424,GO:0044435,GO:0044436,GO:0044444,GO:0044446,GO:0044464,GO:0046149,GO:0046483,GO:0046700,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051187,GO:0051193,GO:0051195,GO:0055035,GO:0065007,GO:0071704,GO:0090056,GO:1901360,GO:1901361,GO:1901401,GO:1901402,GO:1901404,GO:1901405,GO:1901564,GO:1901565,GO:1901575,GO:1903647 4.99.1.10 0.00000000000000000000000000000000000001414 149.0
PYH3_k127_8949117_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 403.0
PYH3_k127_8949117_1 Belongs to the phosphohexose mutase family K22199 - 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 345.0
PYH3_k127_8949117_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000001637 219.0
PYH3_k127_8953511_0 PFAM Metallophosphoesterase K07096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007626 273.0
PYH3_k127_8953511_1 COG1116 ABC-type nitrate sulfonate bicarbonate transport system, ATPase component K02049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002539 256.0
PYH3_k127_8953511_10 TIGRFAM Na H antiporter K03316 - - 0.0000008961 56.0
PYH3_k127_8953511_11 Zinc finger domain - - - 0.0000009485 55.0
PYH3_k127_8953511_12 - - - - 0.00002753 52.0
PYH3_k127_8953511_13 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0001945 46.0
PYH3_k127_8953511_2 Belongs to the UPF0219 family K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000002634 252.0
PYH3_k127_8953511_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.000000000000000000000000000000000000000000000000000001796 205.0
PYH3_k127_8953511_4 amino acid - - - 0.000000000000000000000000000000000000000000000001337 194.0
PYH3_k127_8953511_5 - - - - 0.00000000000000000000000000000000000000000000008581 178.0
PYH3_k127_8953511_6 PFAM ATPase, BadF BadG BcrA BcrD type - - - 0.00000000000000000000000000000000000005324 157.0
PYH3_k127_8953511_7 PFAM Haloacid dehalogenase-like hydrolase K07025 - - 0.00000000000000000000000000000004263 134.0
PYH3_k127_8953511_8 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000001042 119.0
PYH3_k127_8953511_9 Putative zinc- or iron-chelating domain K06940 - - 0.00000000004592 71.0
PYH3_k127_8954664_0 ABC-type dipeptide transport system periplasmic component K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 312.0
PYH3_k127_8954664_1 Glycosyltransferase Family 4 - - - 0.00000000008252 67.0
PYH3_k127_8954664_2 UDP binding domain K00012 - 1.1.1.22 0.0008316 44.0
PYH3_k127_9007877_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 - 5.99.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 427.0
PYH3_k127_9007877_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000618 368.0
PYH3_k127_9007877_10 Phospholipid methyltransferase - - - 0.00000002154 63.0
PYH3_k127_9007877_11 COG4618 ABC-type protease lipase transport system, ATPase and permease components - - - 0.0001491 49.0
PYH3_k127_9007877_2 Peptidase dimerisation domain K01438 - 3.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 323.0
PYH3_k127_9007877_3 peroxiredoxin activity K03564 - 1.11.1.15 0.000000000000000000000000000000000000000000000000003323 186.0
PYH3_k127_9007877_4 deaminase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000004132 187.0
PYH3_k127_9007877_5 galactose-1-phosphate uridylyltransferase - - - 0.000000000000000000000000000000000000000000000000006326 194.0
PYH3_k127_9007877_6 Lysine exporter protein LysE YggA - - - 0.000000000000000000000000000000000000000000000524 174.0
PYH3_k127_9007877_7 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.000000000000000000000000000000000001506 141.0
PYH3_k127_9007877_8 Transcriptional regulator, TrmB - - - 0.00000000000000000000000000004587 132.0
PYH3_k127_9007877_9 Flavin reductase-like protein - - - 0.0000000000000000000000000000849 122.0
PYH3_k127_9087175_0 Molybdenum cofactor synthesis domain protein K03750,K07219 - 2.10.1.1 4.416e-219 698.0
PYH3_k127_9087175_1 in RNase L inhibitor, RLI K06174 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008 615.0
PYH3_k127_9087175_10 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000003414 214.0
PYH3_k127_9087175_11 xanthine phosphoribosyltransferase activity K00769,K07101 - 2.4.2.22 0.000000000000000000000000000000000000000000000000003347 188.0
PYH3_k127_9087175_12 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000004109 173.0
PYH3_k127_9087175_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.0000000000000000000000000000000000000001028 158.0
PYH3_k127_9087175_14 PFAM THUMP domain protein K06963 - - 0.0000000000000000000000000000000001449 141.0
PYH3_k127_9087175_15 Ribosomal protein S8e K02995 - - 0.00000000000000000000000000000001059 131.0
PYH3_k127_9087175_16 Segregation and condensation complex subunit ScpB K06024 - - 0.000000000000000000000000000001272 129.0
PYH3_k127_9087175_17 signal transduction protein with CBS domains - - - 0.000000000000000000000000000009395 123.0
PYH3_k127_9087175_18 TraB family - - - 0.00000000000000000000000001623 119.0
PYH3_k127_9087175_19 PFAM PAC2 family K06869 - - 0.0000000000000000000000001489 116.0
PYH3_k127_9087175_2 PFAM chaperonin Cpn60 TCP-1 K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0042802,GO:0044183,GO:0051082,GO:0061077 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 509.0
PYH3_k127_9087175_20 - - - - 0.00000000000000000000006807 105.0
PYH3_k127_9087175_21 protein conserved in archaea - - - 0.00000000000000003777 92.0
PYH3_k127_9087175_22 - - - - 0.00000000000003301 74.0
PYH3_k127_9087175_23 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000002003 73.0
PYH3_k127_9087175_24 zinc metalloprotease whose natural substrate is K06974 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 - 0.0000000000003312 75.0
PYH3_k127_9087175_25 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000006746 67.0
PYH3_k127_9087175_26 - - - - 0.00000005622 57.0
PYH3_k127_9087175_27 Domain of unknown function (DUF4443) - - - 0.000001075 57.0
PYH3_k127_9087175_28 archaeal coiled-coil protein - - - 0.000198 53.0
PYH3_k127_9087175_29 chromosome segregation and condensation protein ScpA K05896 - - 0.0007687 49.0
PYH3_k127_9087175_3 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 472.0
PYH3_k127_9087175_4 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 395.0
PYH3_k127_9087175_5 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005005 306.0
PYH3_k127_9087175_6 Catalyzes the reversible phosphorylation of S-methyl-5'- thioinosine (MTI) to hypoxanthine and 5-methylthioribose-1- phosphate. Involved in the breakdown of S-methyl-5'-thioadenosine (MTA), a major by-product of polyamine biosynthesis. Catabolism of (MTA) occurs via deamination to MTI and phosphorolysis to hypoxanthine K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000003911 246.0
PYH3_k127_9087175_7 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002356 242.0
PYH3_k127_9087175_8 Molybdenum cofactor synthesis domain protein K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000001425 229.0
PYH3_k127_9087175_9 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000000000000000000000000000000000000000000000000000007729 227.0
PYH3_k127_9089216_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 4.343e-218 691.0
PYH3_k127_9089216_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 4.28e-204 651.0
PYH3_k127_9089216_10 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003131 276.0
PYH3_k127_9089216_11 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000001508 259.0
PYH3_k127_9089216_12 DUF72 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000004729 238.0
PYH3_k127_9089216_13 Electron transfer flavoprotein domain K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000002066 238.0
PYH3_k127_9089216_14 RIO-like serine threonine protein kinase fused to N-terminal HTH domain K07179 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000001056 226.0
PYH3_k127_9089216_15 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000001957 205.0
PYH3_k127_9089216_16 Rossmann fold nucleotide-binding protein K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000003102 186.0
PYH3_k127_9089216_17 PFAM Pyruvate K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000002421 180.0
PYH3_k127_9089216_18 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000006654 166.0
PYH3_k127_9089216_19 reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000004118 162.0
PYH3_k127_9089216_2 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 543.0
PYH3_k127_9089216_20 Thiamine biosynthesis protein (ThiI) K06920 - 6.3.4.20 0.0000000000000000000000000000000000002209 149.0
PYH3_k127_9089216_21 nUDIX hydrolase K01515,K01518,K01814 - 3.6.1.13,3.6.1.17,5.3.1.16 0.000000000000000000000000000000000004008 143.0
PYH3_k127_9089216_22 Phosphate transporter family K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.00000000000000000000000000000000001768 147.0
PYH3_k127_9089216_24 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000006617 123.0
PYH3_k127_9089216_25 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000003485 106.0
PYH3_k127_9089216_26 - - - - 0.00000000000000000001571 99.0
PYH3_k127_9089216_27 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00176 - 1.2.7.3 0.0000000000000131 78.0
PYH3_k127_9089216_28 Phosphate transport regulator K07220 - - 0.0000000000005735 79.0
PYH3_k127_9089216_29 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000001434 78.0
PYH3_k127_9089216_3 PFAM tRNA synthetase, class II (D, K and N) K01893 - 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007754 445.0
PYH3_k127_9089216_30 DNA polymerase beta domain protein region - - - 0.000000561 59.0
PYH3_k127_9089216_31 Probable zinc-ribbon domain - - - 0.000001984 53.0
PYH3_k127_9089216_32 Limonene-1,2-epoxide hydrolase - - - 0.00001187 53.0
PYH3_k127_9089216_33 ThiS family K03636 - - 0.00001355 51.0
PYH3_k127_9089216_4 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000395 411.0
PYH3_k127_9089216_5 Catalyzes the addition of molecular CO(2) and H(2)O to ribulose 1,5-bisphosphate (RuBP), generating two molecules of 3- phosphoglycerate (3-PGA). Functions in an archaeal AMP degradation pathway, together with AMP phosphorylase and R15P isomerase K01601 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006857 407.0
PYH3_k127_9089216_6 ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003347 388.0
PYH3_k127_9089216_7 Belongs to the eIF-2B alpha beta delta subunits family K18237 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 360.0
PYH3_k127_9089216_8 ferredoxin oxidoreductase, subunit beta K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 335.0
PYH3_k127_9089216_9 TIM-barrel fold metal-dependent hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008219 310.0
PYH3_k127_9099926_0 2-hydroxyglutaryl-CoA dehydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003351 351.0
PYH3_k127_9099926_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 335.0
PYH3_k127_9099926_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000447 228.0
PYH3_k127_9099926_3 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000003541 113.0
PYH3_k127_9143568_0 GDSL-like Lipase/Acylhydrolase - - - 0.000000000000009911 85.0
PYH3_k127_9199546_0 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003124 300.0
PYH3_k127_935874_0 TPP binding domain K01652 - 2.2.1.6 2.965e-212 673.0
PYH3_k127_935874_1 SCP-2 sterol transfer family - - - 0.0000000000000000000000000000000000000009081 152.0
PYH3_k127_935874_2 PFAM iron-containing alcohol dehydrogenase - - - 0.0000000000000000005508 89.0
PYH3_k127_9421948_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 387.0
PYH3_k127_9421948_1 FAD-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003514 328.0
PYH3_k127_9421948_2 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000002427 214.0
PYH3_k127_9421948_3 redox protein regulator of disulfide bond formation - - - 0.0000000000000000000001158 99.0
PYH3_k127_9421948_4 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.000000000000000000004116 97.0
PYH3_k127_9477840_0 formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000203 374.0
PYH3_k127_9477840_1 Catalyzes the reversible interconversion of 5-formyl- H(4)MPT to methenyl-H(4)MPT( K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 325.0
PYH3_k127_9477840_2 PFAM glutamate synthase alpha subunit domain protein K00202 - 1.2.7.12 0.00000000000000000000000000000000000000000000003942 179.0
PYH3_k127_9477840_3 DNA polymerase beta domain protein region K09717 - - 0.0000000000000000000000000000000000000000003917 171.0
PYH3_k127_9477840_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.0000000000000000000000000000000001458 145.0
PYH3_k127_9524034_0 Radical SAM domain protein K06937 - - 1.104e-217 687.0
PYH3_k127_9524034_1 Large family of predicted nucleotide-binding domains K06865 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001582 536.0
PYH3_k127_9524034_2 PFAM thioesterase superfamily K07107 - - 0.00000000000000007723 85.0
PYH3_k127_9611742_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 588.0
PYH3_k127_9611742_1 TIGRFAM DNA polymerase (pol2) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003363 492.0
PYH3_k127_9611742_10 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.00000000000000000000000000000000000000000000000000000000005025 219.0
PYH3_k127_9611742_11 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000003439 206.0
PYH3_k127_9611742_12 Located on the platform of the 30S subunit K02948 GO:0000028,GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0048027,GO:0065003,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000001784 199.0
PYH3_k127_9611742_13 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000003627 208.0
PYH3_k127_9611742_14 Peptidase M28 - - - 0.00000000000000000000000000000000000000002273 171.0
PYH3_k127_9611742_15 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000008048 159.0
PYH3_k127_9611742_16 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000009999 147.0
PYH3_k127_9611742_17 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000005745 126.0
PYH3_k127_9611742_18 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000004039 109.0
PYH3_k127_9611742_19 pyridoxamine 5'-phosphate oxidase-related, FMN-binding - - - 0.0000002051 59.0
PYH3_k127_9611742_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002461 434.0
PYH3_k127_9611742_20 - - - - 0.00008333 51.0
PYH3_k127_9611742_3 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 404.0
PYH3_k127_9611742_4 PFAM Thiolase K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 314.0
PYH3_k127_9611742_5 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003134 308.0
PYH3_k127_9611742_6 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007485 280.0
PYH3_k127_9611742_7 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000179 276.0
PYH3_k127_9611742_8 PFAM PP-loop domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006897 261.0
PYH3_k127_9611742_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000003085 231.0
PYH3_k127_9616469_0 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 496.0
PYH3_k127_9616469_1 Diacylglycerol kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001667 261.0
PYH3_k127_9616469_2 - - - - 0.0000000000000000000000000000000000000000000000000000003604 201.0
PYH3_k127_9616469_3 Membrane - - - 0.00000000000001276 76.0
PYH3_k127_9616469_4 Domain of unknown function (DUF1893) - - - 0.00000000000002536 76.0