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Overview

ID MAG03219
Name PYH3_bin.23
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family UBA6910
Genus UBA6910
Species
Assembly information
Completeness (%) 60.41
Contamination (%) 0.01
GC content (%) 70.0
N50 (bp) 4,090
Genome size (bp) 1,893,815

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes2034

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1002221_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 541.0
PYH3_k127_1002221_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000004169 214.0
PYH3_k127_1003903_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 2.288e-202 634.0
PYH3_k127_1003903_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 497.0
PYH3_k127_1003903_2 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001609 387.0
PYH3_k127_1003903_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000001086 57.0
PYH3_k127_1013730_0 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 532.0
PYH3_k127_1013730_1 PFAM Adenylyl cyclase class-3 4 guanylyl cyclase K01769 - 4.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 441.0
PYH3_k127_1013730_2 Zinc-finger domain - - - 0.0000000000000000000000000002722 114.0
PYH3_k127_1019103_0 Phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000231 540.0
PYH3_k127_1019103_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000001055 62.0
PYH3_k127_1040796_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 462.0
PYH3_k127_1040796_1 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 356.0
PYH3_k127_1040796_2 Alpha beta hydrolase superfamily - - - 0.000000000000000000000000000000000000002881 154.0
PYH3_k127_1040796_3 Single cache domain 3 - - - 0.0000000000002486 69.0
PYH3_k127_1046128_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 9.083e-214 670.0
PYH3_k127_1046128_1 TIGRFAM DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 332.0
PYH3_k127_1046128_2 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 0.000000000000000000000000000000000008032 141.0
PYH3_k127_1053213_0 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 1.33e-269 839.0
PYH3_k127_1053213_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 615.0
PYH3_k127_1053213_2 dehydrogenase reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002021 286.0
PYH3_k127_1053213_3 Thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000006027 149.0
PYH3_k127_1062301_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006609 541.0
PYH3_k127_1062301_1 Lumazine binding domain K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000001489 261.0
PYH3_k127_1062301_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.000000000000000000000000000000000000000000000000000000000000000003104 230.0
PYH3_k127_1062301_3 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003837 228.0
PYH3_k127_1062301_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000000000000000000000000000000001784 184.0
PYH3_k127_1067938_0 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 504.0
PYH3_k127_1067938_1 Mechanosensitive ion channel K05802,K22051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 389.0
PYH3_k127_1075631_0 Peptidase U32 K08303 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 524.0
PYH3_k127_1075631_1 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 381.0
PYH3_k127_1084741_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.534e-204 649.0
PYH3_k127_1084741_1 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005382 356.0
PYH3_k127_1084741_2 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001629 269.0
PYH3_k127_1084741_3 Protein of unknown function DUF45 K07043 - - 0.000000000000000003584 97.0
PYH3_k127_1091408_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 548.0
PYH3_k127_1091408_1 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000000338 146.0
PYH3_k127_110094_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000016 445.0
PYH3_k127_110094_1 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003032 342.0
PYH3_k127_110094_2 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001371 335.0
PYH3_k127_110094_3 Formaldehyde-activating enzyme (Fae) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001799 303.0
PYH3_k127_110094_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000003775 239.0
PYH3_k127_110094_5 ThiS family K03154 - - 0.000000000000000000002249 95.0
PYH3_k127_1109242_0 formate dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000005471 203.0
PYH3_k127_1109242_1 anaerobic respiration - - - 0.00000000000000000000000000000001588 134.0
PYH3_k127_1146142_0 synthetase, class II (G H P K01892 - 6.1.1.21 4.67e-197 622.0
PYH3_k127_1146142_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002676 353.0
PYH3_k127_1146142_2 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000001005 233.0
PYH3_k127_1146142_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.000000000000000000000000000000000000000000000000001889 189.0
PYH3_k127_1149666_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 492.0
PYH3_k127_1149666_1 Prephenate dehydratase K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 484.0
PYH3_k127_1149666_2 Prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000002815 125.0
PYH3_k127_1154326_0 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 496.0
PYH3_k127_1154326_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000001251 53.0
PYH3_k127_1164986_0 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 389.0
PYH3_k127_1164986_2 import inner membrane translocase subunit Tim44 - - - 0.0004857 43.0
PYH3_k127_1191993_0 FAD binding domain K00394 - 1.8.99.2 0.0 1002.0
PYH3_k127_1191993_1 PFAM AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001784 396.0
PYH3_k127_1191993_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006288 384.0
PYH3_k127_1191993_3 PFAM von Willebrand factor type A K02448 - - 0.0000000000000000000000000000000000000000003027 167.0
PYH3_k127_1201216_0 PFAM Fructosamine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001601 379.0
PYH3_k127_1201216_1 Domain of unknown function (DUF4124) - - - 0.0000000003012 68.0
PYH3_k127_1202259_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000002979 131.0
PYH3_k127_1205374_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 4.685e-250 782.0
PYH3_k127_1205374_1 Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 3.487e-195 620.0
PYH3_k127_1205374_2 Mediates influx of magnesium ions K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 408.0
PYH3_k127_1205374_3 SCO1 SenC K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 356.0
PYH3_k127_1205374_4 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 321.0
PYH3_k127_1205374_5 Hint domain - - - 0.0000000004379 68.0
PYH3_k127_121849_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K21307 - 1.8.5.6 0.0 1709.0
PYH3_k127_121849_1 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 497.0
PYH3_k127_121849_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002441 450.0
PYH3_k127_121849_3 DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005402 266.0
PYH3_k127_121849_4 Iron/manganese superoxide dismutases, C-terminal domain K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000001362 212.0
PYH3_k127_121849_5 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01758,K01761 - 4.4.1.1,4.4.1.11 0.0000000000002244 70.0
PYH3_k127_1233476_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1116.0
PYH3_k127_1233476_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 347.0
PYH3_k127_1233476_2 Metallo-beta-lactamase superfamily K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 320.0
PYH3_k127_1254326_0 Virulence factor BrkB K07058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 332.0
PYH3_k127_1254326_1 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 297.0
PYH3_k127_1254326_2 - - - - 0.00000006674 57.0
PYH3_k127_1258996_0 PFAM Alanine dehydrogenase PNT K00324 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 459.0
PYH3_k127_1258996_1 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006272 351.0
PYH3_k127_1258996_2 4TM region of pyridine nucleotide transhydrogenase, mitoch K00322,K00324 - 1.6.1.1,1.6.1.2 0.00000000000000000000000000000000000002224 145.0
PYH3_k127_1277617_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 2466.0
PYH3_k127_1277617_1 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 522.0
PYH3_k127_1277617_2 glutamate synthase K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009893 285.0
PYH3_k127_1299996_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006717 338.0
PYH3_k127_1299996_1 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 306.0
PYH3_k127_1299996_2 - - - - 0.000000000000000000000000000003694 126.0
PYH3_k127_1302923_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.575e-223 710.0
PYH3_k127_1302923_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005704 331.0
PYH3_k127_1305552_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00956 - 2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005101 567.0
PYH3_k127_1305552_1 Phosphoadenosine phosphosulfate reductase family K00957 - 2.7.7.4 0.000000000000000000000000001916 112.0
PYH3_k127_1357648_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1252.0
PYH3_k127_1357648_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000429 580.0
PYH3_k127_1357648_2 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000001912 149.0
PYH3_k127_1357648_3 - - - - 0.000000000000000000000002052 112.0
PYH3_k127_1357648_4 Belongs to the CinA family K03743 GO:0003674,GO:0003824,GO:0016787,GO:0016810,GO:0016811,GO:0019159 3.5.1.42 0.0002688 44.0
PYH3_k127_1399323_0 FAD linked oxidases, C-terminal domain K18930 - - 0.0 1295.0
PYH3_k127_1399323_1 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 608.0
PYH3_k127_1399323_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004805 582.0
PYH3_k127_1399323_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 466.0
PYH3_k127_1399323_4 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007342 339.0
PYH3_k127_1399323_5 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 312.0
PYH3_k127_1399323_6 Protein of unknown function (DUF3530) - - - 0.00000000000000000000000000000000000000000000000000000000000000001184 247.0
PYH3_k127_1399323_7 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000005387 178.0
PYH3_k127_1399323_8 nitrogen regulatory protein P-II - - - 0.0000000000000266 73.0
PYH3_k127_1399323_9 enoyl-CoA hydratase - - - 0.00000000000003535 86.0
PYH3_k127_1405753_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.197e-266 835.0
PYH3_k127_1427665_0 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 401.0
PYH3_k127_1427665_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001691 267.0
PYH3_k127_1427665_2 Universal stress protein - - - 0.00000000000000000000000000000000001151 144.0
PYH3_k127_1427665_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000117 119.0
PYH3_k127_1429382_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1051.0
PYH3_k127_1429382_1 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.0000000000000000000000000625 108.0
PYH3_k127_1482298_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006098 518.0
PYH3_k127_1482298_1 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002538 469.0
PYH3_k127_1482298_2 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
PYH3_k127_1504799_0 glutaminyl-tRNA K01886 - 6.1.1.18 3.82e-273 850.0
PYH3_k127_1504799_1 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 9.644e-225 709.0
PYH3_k127_1504799_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000814 360.0
PYH3_k127_1504799_3 Pfam:Pyridox_oxidase K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007197 245.0
PYH3_k127_1504799_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000102 233.0
PYH3_k127_1504799_5 Protein of unknown function (DUF3617) - - - 0.00000000000000000009725 94.0
PYH3_k127_1510677_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 8.401e-272 852.0
PYH3_k127_1510677_1 Acyl-CoA dehydrogenase, middle domain K00252 - 1.3.8.6 3.022e-217 679.0
PYH3_k127_1510677_2 acyl-CoA transferases carnitine dehydratase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 584.0
PYH3_k127_1510677_3 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 356.0
PYH3_k127_1510677_4 addiction module antidote protein - - - 0.00000000000000000000000000000000000000000001152 164.0
PYH3_k127_1510677_5 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000009457 127.0
PYH3_k127_1510677_6 toxin-antitoxin pair type II binding - - - 0.0000000000000008445 79.0
PYH3_k127_1510677_7 - - - - 0.0002172 51.0
PYH3_k127_1539466_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 6.723e-249 774.0
PYH3_k127_1539466_2 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000003113 55.0
PYH3_k127_1561134_0 Peptidase family M13 K01415,K07386 - 3.4.24.71 3.408e-202 641.0
PYH3_k127_1567833_0 signal transduction histidine kinase K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000003251 252.0
PYH3_k127_1567833_1 PFAM response regulator receiver K15012 - - 0.0000000000000000000000000000000000000000000000000000000007536 209.0
PYH3_k127_1567833_2 LuxR family transcriptional regulator K13041 - - 0.000000000000006343 76.0
PYH3_k127_1581687_0 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 388.0
PYH3_k127_1581687_1 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007957 322.0
PYH3_k127_1620684_0 UDP binding domain K02474 - - 2.234e-202 646.0
PYH3_k127_1620684_1 Nucleotidyl transferase K00978 - 2.7.7.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004624 427.0
PYH3_k127_1620684_2 PFAM NAD-dependent epimerase dehydratase K01709 - 4.2.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 407.0
PYH3_k127_1620684_3 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000001885 253.0
PYH3_k127_1642744_0 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 477.0
PYH3_k127_1642744_1 serine threonine protein kinase - - - 0.00000000000000000000000000000003331 131.0
PYH3_k127_1650667_0 PFAM ATPase associated with various cellular activities AAA_3 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 434.0
PYH3_k127_1654090_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 2.028e-293 909.0
PYH3_k127_1654090_1 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006925 463.0
PYH3_k127_1654090_2 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008622 372.0
PYH3_k127_1654090_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002358 250.0
PYH3_k127_1654090_4 Protein conserved in bacteria - - - 0.0000000000000912 84.0
PYH3_k127_1659662_0 Formyl transferase K19640 - - 2.182e-203 643.0
PYH3_k127_1659662_1 Belongs to the HypD family K04654 - - 9.138e-199 628.0
PYH3_k127_1659662_2 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003658 580.0
PYH3_k127_1659662_3 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000000000000000000000000000000000000000000000004933 218.0
PYH3_k127_1659662_4 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000001621 116.0
PYH3_k127_1662951_0 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003305 264.0
PYH3_k127_1662951_1 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000003215 223.0
PYH3_k127_1662951_2 Pyridine nucleotide-disulphide oxidoreductase K05297,K12265 - 1.18.1.1 0.00000000000000000000000000000000000000000000000000002727 200.0
PYH3_k127_1662951_3 Transcriptional regulator K04761 - - 0.00000000000000000000000000000000001481 137.0
PYH3_k127_1662951_4 Rubredoxin - - - 0.000000000000000000000000009988 119.0
PYH3_k127_1671_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006359 386.0
PYH3_k127_1671_1 HD domain K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000007177 254.0
PYH3_k127_1671_2 Putative heavy-metal chelation - - - 0.00000000000000000000000000000000000000000000000000000397 197.0
PYH3_k127_1671_3 - - - - 0.000000000000000000000001386 106.0
PYH3_k127_1672811_0 Transcriptional regulator, Crp Fnr family K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 300.0
PYH3_k127_1672811_1 biotin lipoate A B protein ligase K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009925 270.0
PYH3_k127_1672811_2 His Kinase A (phosphoacceptor) domain - - - 0.0000747 47.0
PYH3_k127_1694378_0 His Kinase A (phospho-acceptor) domain - - - 4.342e-280 870.0
PYH3_k127_1696211_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 7.173e-234 727.0
PYH3_k127_1696211_1 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 420.0
PYH3_k127_1696211_2 Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC) K02551 - 2.2.1.9 0.00000000000000000000000000000000000000000000000000000208 197.0
PYH3_k127_1696211_3 TIGRFAM phasin family protein - - - 0.000000000000000000000000000000007399 132.0
PYH3_k127_1747217_0 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002906 348.0
PYH3_k127_1747217_1 PFAM NADH flavin oxidoreductase NADH oxidase K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000005459 229.0
PYH3_k127_1747217_2 2'-5' RNA ligase superfamily - - - 0.0000000000000000000000000000000000000000000004655 173.0
PYH3_k127_1747217_3 Uncharacterized protein conserved in bacteria (DUF2322) - - - 0.00000000000000000000000000000000000000001774 164.0
PYH3_k127_1747217_4 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000000000000000000000000007979 149.0
PYH3_k127_1765436_0 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003132 591.0
PYH3_k127_1765436_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 320.0
PYH3_k127_1765436_2 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001387 267.0
PYH3_k127_177122_0 Peptidase family M28 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 313.0
PYH3_k127_177122_1 Belongs to the MtfA family K09933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001004 288.0
PYH3_k127_1771383_0 PFAM HupH hydrogenase expression protein K03618 - - 0.00000000000000000000000000000000000000000000000000000000000000000002816 241.0
PYH3_k127_1771383_1 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000009769 133.0
PYH3_k127_1771383_2 Rubredoxin - - - 0.00000000000000000000002218 109.0
PYH3_k127_1784935_0 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000000000000000000000004313 126.0
PYH3_k127_1784935_1 - - - - 0.000000000000000000003181 99.0
PYH3_k127_1784935_2 - - - - 0.00006775 53.0
PYH3_k127_1804960_0 Binding-protein-dependent transport system inner membrane component K02018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 313.0
PYH3_k127_1804960_1 Molybdenum ABC transporter K02020 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007728 283.0
PYH3_k127_1804960_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02045 - 3.6.3.25 0.000000000000002702 79.0
PYH3_k127_1814241_0 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 482.0
PYH3_k127_1814241_1 Signal transduction histidine kinase, subgroup 1, dimerisation phosphoacceptor K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000313 313.0
PYH3_k127_1821120_0 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 433.0
PYH3_k127_1821120_1 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008381 428.0
PYH3_k127_1821120_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006192 303.0
PYH3_k127_1821120_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000001556 218.0
PYH3_k127_1821120_4 Domain of unknown function (DUF4124) - - - 0.00000000000000000000000002042 119.0
PYH3_k127_1839049_0 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 355.0
PYH3_k127_1839049_1 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007752 269.0
PYH3_k127_1851025_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 511.0
PYH3_k127_1851025_1 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 383.0
PYH3_k127_1851025_2 FR47-like protein - - - 0.00000000000000000000000002051 123.0
PYH3_k127_1857809_0 Biotin carboxylase C-terminal domain K01965,K01968,K13777 - 6.4.1.3,6.4.1.4,6.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 437.0
PYH3_k127_1857809_1 COG0119 Isopropylmalate homocitrate citramalate synthases K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000002449 196.0
PYH3_k127_186370_0 PFAM Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 547.0
PYH3_k127_186370_1 PFAM Bacterial extracellular solute-binding proteins, family 3 K09969 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008584 319.0
PYH3_k127_186370_2 - - - - 0.0009404 51.0
PYH3_k127_1869026_0 Esterase, phb depolymerase family - - - 0.000000000000000000000000000000000000001893 150.0
PYH3_k127_1869026_2 - - - - 0.0000000003943 71.0
PYH3_k127_1927092_0 HELICc2 K03722 - 3.6.4.12 5.713e-274 857.0
PYH3_k127_1927092_1 Cytochrome c bacterial - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005692 611.0
PYH3_k127_1927092_2 PFAM Pyridoxal-dependent decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001248 542.0
PYH3_k127_1927092_3 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001749 328.0
PYH3_k127_1927092_4 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008008 311.0
PYH3_k127_1927092_5 - - - - 0.00000000000000000000000000000217 136.0
PYH3_k127_1927092_6 Universal stress protein family - - - 0.00000000000000000000003164 104.0
PYH3_k127_2001692_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007631 571.0
PYH3_k127_2001692_1 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 448.0
PYH3_k127_2001692_2 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 395.0
PYH3_k127_2001692_3 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 377.0
PYH3_k127_2001692_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003736 354.0
PYH3_k127_2001692_5 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007532 243.0
PYH3_k127_2001692_6 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000003111 207.0
PYH3_k127_2067247_0 Pyridine nucleotide-disulphide oxidoreductase K00528 - 1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005173 484.0
PYH3_k127_2067247_1 Molybdopterin oxidoreductase K00201 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001308 464.0
PYH3_k127_2067247_2 4Fe-4S binding domain K05524 - - 0.0000000000000000000000000000000000008361 142.0
PYH3_k127_2067247_3 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.000000000000000000000000000000001437 132.0
PYH3_k127_2067247_4 PFAM molydopterin dinucleotide-binding region K00203,K00336 - 1.2.7.12,1.6.5.3 0.00000000000000003861 85.0
PYH3_k127_2108828_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 509.0
PYH3_k127_2108828_1 TGS domain K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003753 377.0
PYH3_k127_2108828_2 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003971 353.0
PYH3_k127_2108828_3 Specifically methylates the adenine in position 2030 of 23S rRNA K07115 - 2.1.1.266 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000055 292.0
PYH3_k127_2108828_4 methionine sulfoxide reductase K07305,K12267 GO:0003674,GO:0003824,GO:0008113,GO:0008150,GO:0008152,GO:0009405,GO:0016491,GO:0016667,GO:0016671,GO:0044419,GO:0051704,GO:0055114 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000004964 242.0
PYH3_k127_2108828_5 Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate K01619 - 4.1.2.4 0.0000000000000000000000000000000000000000000000000000000000003011 220.0
PYH3_k127_2108828_6 PBP superfamily domain K02040 - - 0.000000000000000000000000000000000000000000000000004911 192.0
PYH3_k127_2108828_7 MazG-like family - - - 0.00000000000000000000000000000000002819 138.0
PYH3_k127_2108828_8 GDSL-like Lipase/Acylhydrolase - - - 0.000001662 61.0
PYH3_k127_2121365_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 4.328e-218 685.0
PYH3_k127_2121365_1 - - - - 0.000000001047 66.0
PYH3_k127_2121365_2 PFAM Cytochrome c assembly protein - - - 0.00000001129 57.0
PYH3_k127_2122554_0 Bacterial DNA polymerase III alpha subunit K14162 - 2.7.7.7 2.649e-294 913.0
PYH3_k127_2178074_0 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 9.927e-209 655.0
PYH3_k127_2178074_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 533.0
PYH3_k127_2180334_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 595.0
PYH3_k127_2180334_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000005439 134.0
PYH3_k127_2180334_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000004576 117.0
PYH3_k127_2180478_0 Iron-sulfur cluster-binding domain K06139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 554.0
PYH3_k127_2180478_1 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002033 389.0
PYH3_k127_2180478_2 pfam abc K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001228 352.0
PYH3_k127_2180478_3 Transport Permease Protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001119 285.0
PYH3_k127_2180478_4 May be involved in the transport of PQQ or its precursor to the periplasm K06136 - - 0.0000000000000000000000000000000000000000000000000000000000000000003194 231.0
PYH3_k127_2180478_5 amidohydrolase - - - 0.00000000000000000000000000000000000000000000000003516 186.0
PYH3_k127_2180478_6 Phasin protein - - - 0.000000000000000000000000000000000002402 145.0
PYH3_k127_2184069_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007377 527.0
PYH3_k127_2184069_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004186 443.0
PYH3_k127_2184069_2 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.000000000000000000000004235 117.0
PYH3_k127_2190851_0 - - - - 0.000000000009173 77.0
PYH3_k127_2190851_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.000009186 53.0
PYH3_k127_2190851_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0006363 46.0
PYH3_k127_2198908_0 Lactoylglutathione lyase and related lyases K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001047 267.0
PYH3_k127_2198908_1 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000000000000000000001057 237.0
PYH3_k127_2198908_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000002945 193.0
PYH3_k127_2198908_3 Domain of unknown function (DUF1924) - - - 0.000000000000000000000000000000000000000000008028 167.0
PYH3_k127_2198908_4 PFAM Di-haem cytochrome c - - - 0.00000000000000000000000000000000000000000004707 172.0
PYH3_k127_2198908_5 Muconolactone delta-isomerase K03464 - 5.3.3.4 0.0000000000000000000000000000000000000000005108 160.0
PYH3_k127_2198908_6 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000001818 70.0
PYH3_k127_2210986_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 585.0
PYH3_k127_2210986_1 Elongation factor P K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001201 246.0
PYH3_k127_2211180_0 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007784 299.0
PYH3_k127_2211180_1 Predicted membrane protein (DUF2157) - - - 0.00000000000000000000000000000000001446 140.0
PYH3_k127_2224107_0 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 508.0
PYH3_k127_2224107_1 ABC transporter K06158 - - 0.00008235 46.0
PYH3_k127_2233111_0 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007159 305.0
PYH3_k127_2233111_1 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000001283 240.0
PYH3_k127_2233111_2 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000008176 168.0
PYH3_k127_2244959_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000001399 181.0
PYH3_k127_2244959_1 - - - - 0.00000000241 59.0
PYH3_k127_2244959_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000001246 60.0
PYH3_k127_2249876_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.47e-220 689.0
PYH3_k127_2249876_1 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005314 426.0
PYH3_k127_2249876_2 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003135 252.0
PYH3_k127_2249876_3 Phasin protein - - - 0.00000000000000000000000000000000000000003474 159.0
PYH3_k127_2249876_4 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000987 48.0
PYH3_k127_2266754_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 2.369e-287 886.0
PYH3_k127_2266754_1 Beta-Casp domain K07576 - - 4.135e-195 625.0
PYH3_k127_2266754_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 552.0
PYH3_k127_2266754_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 573.0
PYH3_k127_2266754_4 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 414.0
PYH3_k127_2266754_5 Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway K03181 - 4.1.3.40 0.00000000000000000000000000000000000000000000000000000002818 202.0
PYH3_k127_2266754_6 membrane - - - 0.0000000000000000000000000000000000000000008664 162.0
PYH3_k127_2266754_7 Bacterial protein of unknown function (DUF883) - - - 0.0000000000000000000000000000003372 128.0
PYH3_k127_2266754_8 Psort location Cytoplasmic, score 8.96 - - - 0.0000000000000000000000000000004242 125.0
PYH3_k127_2266754_9 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000135 75.0
PYH3_k127_2290591_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 9.642e-274 854.0
PYH3_k127_2290591_1 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 2.138e-194 617.0
PYH3_k127_2290591_10 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006484 290.0
PYH3_k127_2290591_11 preprotein translocase subunit YajC K03210 - - 0.0000000000000000000000000000000006199 135.0
PYH3_k127_2290591_12 response regulator - - - 0.0000000000000000001348 94.0
PYH3_k127_2290591_13 PFAM Thioredoxin K05838 - - 0.000000000002177 68.0
PYH3_k127_2290591_14 Alginate export - - - 0.000949 51.0
PYH3_k127_2290591_2 GDP-mannose 4,6 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 606.0
PYH3_k127_2290591_3 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 604.0
PYH3_k127_2290591_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 500.0
PYH3_k127_2290591_5 NmrA-like family K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 486.0
PYH3_k127_2290591_6 Catalyzes the two-step NADP-dependent conversion of GDP- 4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction K02377 - 1.1.1.271 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004706 480.0
PYH3_k127_2290591_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008087 476.0
PYH3_k127_2290591_8 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 390.0
PYH3_k127_2290591_9 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 371.0
PYH3_k127_2295192_0 Methylmalonyl-CoA mutase K01847 - 5.4.99.2 0.0 1139.0
PYH3_k127_2295192_1 Biotin carboxylase C-terminal domain K01965 - 6.4.1.3 1.583e-301 937.0
PYH3_k127_2295192_2 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 1.057e-292 902.0
PYH3_k127_2295192_3 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 461.0
PYH3_k127_2295192_4 Histidine kinase K07645 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 2.7.13.3 0.00000000000003107 74.0
PYH3_k127_2298763_0 Belongs to the peptidase S16 family - - - 2.279e-255 805.0
PYH3_k127_2315454_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 9.314e-269 834.0
PYH3_k127_2315454_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 327.0
PYH3_k127_2323451_0 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001362 284.0
PYH3_k127_2323451_1 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008283 281.0
PYH3_k127_2323451_2 COG2010 Cytochrome c, mono- and diheme variants - - - 0.00000000000000000000000000000000001472 144.0
PYH3_k127_2327891_0 Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.0 1022.0
PYH3_k127_2327891_1 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002736 251.0
PYH3_k127_2327891_2 Lipocalin-like domain K03098 - - 0.00000000000000000000000000000000000000000000008667 190.0
PYH3_k127_2327891_3 - - - - 0.0000000000000000000000000009809 119.0
PYH3_k127_2327891_4 YMGG-like Gly-zipper - - - 0.000000006705 57.0
PYH3_k127_2345237_0 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 521.0
PYH3_k127_2345237_1 dihydroorotase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000365 312.0
PYH3_k127_2345237_2 Phosphoribosyl transferase domain K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000005496 217.0
PYH3_k127_2368435_0 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 6.528e-220 705.0
PYH3_k127_2368435_1 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000000000174 234.0
PYH3_k127_2368435_2 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000002291 183.0
PYH3_k127_2368435_3 Divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000000000006307 144.0
PYH3_k127_2368435_4 Nad-dependent epimerase dehydratase - - - 0.0000000000000007761 78.0
PYH3_k127_2368435_5 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.00000000001471 65.0
PYH3_k127_2385327_0 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 495.0
PYH3_k127_2385327_1 Protein of unknown function (DUF4197) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 267.0
PYH3_k127_2385327_2 Thioredoxin-like - - - 0.00000000000000000000000000007437 124.0
PYH3_k127_2385327_3 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009249,GO:0009987,GO:0010467,GO:0018065,GO:0018193,GO:0018205,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0071704,GO:1901564 2.3.1.181 0.000000000000000000001007 95.0
PYH3_k127_2389469_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 4.101e-262 826.0
PYH3_k127_2389469_1 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 299.0
PYH3_k127_2389469_2 Aerobic-type carbon monoxide dehydrogenase small subunit CoxS K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000000000000002673 241.0
PYH3_k127_2389469_3 COG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000003104 224.0
PYH3_k127_2389469_4 - - - - 0.000000000000001389 79.0
PYH3_k127_2408565_0 von Willebrand factor (vWF) type A domain K02448 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 426.0
PYH3_k127_2408565_1 Belongs to the Nudix hydrolase family. NudC subfamily K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005938 278.0
PYH3_k127_2408565_2 MaoC like domain - - - 0.000000000000000000000000000000000000000007041 171.0
PYH3_k127_2455185_0 Glucose / Sorbosone dehydrogenase - - - 2.371e-234 730.0
PYH3_k127_2455185_1 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 1.112e-215 684.0
PYH3_k127_2455185_2 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005432 264.0
PYH3_k127_2455185_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000000000000000000000000000000000000000004524 209.0
PYH3_k127_2455185_4 Cytochrome c - - - 0.00000000000000000000008307 109.0
PYH3_k127_248950_0 Prokaryotic N-terminal methylation motif K02456 - - 0.0000000000000000000000000000000000000000000000000000001628 206.0
PYH3_k127_248950_1 Type II secretion system protein G K02456 - - 0.0000000000000000000000000000000000000000000002515 170.0
PYH3_k127_248950_2 Type II secretory pathway pseudopilin - - - 0.00000000000000000000000000000000000000000007433 171.0
PYH3_k127_248950_3 Secretin and TonB N terminus short domain K02453 - - 0.0000000002074 66.0
PYH3_k127_249324_0 SNARE associated Golgi protein - - - 0.0 1041.0
PYH3_k127_249324_1 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 561.0
PYH3_k127_249324_2 Protein of unknown function (DUF3641) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 471.0
PYH3_k127_249324_3 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 326.0
PYH3_k127_249324_4 ABC transporter K06158 - - 0.00000000000000000004142 93.0
PYH3_k127_2529726_0 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001606 537.0
PYH3_k127_2529726_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 293.0
PYH3_k127_2529726_2 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000003115 104.0
PYH3_k127_2529726_3 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000001185 93.0
PYH3_k127_2532724_0 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008935 416.0
PYH3_k127_2532724_1 squalene-associated FAD-dependent desaturase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000002546 188.0
PYH3_k127_2532724_2 Fe-S metabolism associated domain K02426 - - 0.000009944 49.0
PYH3_k127_2556027_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002942 589.0
PYH3_k127_2556027_1 Branched-chain amino acid ATP-binding cassette transporter K06861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 392.0
PYH3_k127_2556027_2 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000000000000000000000000003325 191.0
PYH3_k127_2556027_3 protein conserved in bacteria K11719 - - 0.00000000000000000000000000000000000000000001924 169.0
PYH3_k127_2556027_4 Sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000006814 145.0
PYH3_k127_2556027_5 Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate K03270 - 3.1.3.45 0.00000003135 55.0
PYH3_k127_2575317_0 PFAM glycosyl transferase, family 35 K00688 - 2.4.1.1 0.0 1260.0
PYH3_k127_2575317_1 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 284.0
PYH3_k127_2575317_2 Peptidase, M48 K06013 - 3.4.24.84 0.000000000000003438 78.0
PYH3_k127_2575317_3 Protein of unknown function (DUF2934) - - - 0.000001373 50.0
PYH3_k127_2580285_0 Alpha/beta hydrolase of unknown function (DUF915) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 386.0
PYH3_k127_2580285_1 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 369.0
PYH3_k127_2580285_2 DsrC like protein K11179 - - 0.000000000000000000000000000000739 126.0
PYH3_k127_2580285_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000001235 123.0
PYH3_k127_2586349_0 GGDEF domain - - - 4.699e-219 696.0
PYH3_k127_2589231_0 Belongs to the CarB family K01955 - 6.3.5.5 2.739e-273 846.0
PYH3_k127_2589231_1 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 606.0
PYH3_k127_2589231_2 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007956 408.0
PYH3_k127_2589231_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002578 258.0
PYH3_k127_2589231_4 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000001003 237.0
PYH3_k127_2589231_5 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.00000000000000000000000000000000002307 143.0
PYH3_k127_2590187_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1244.0
PYH3_k127_2590187_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 2.583e-198 627.0
PYH3_k127_2590187_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 488.0
PYH3_k127_2590187_3 N-terminal domain of oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 432.0
PYH3_k127_2590187_4 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000002813 232.0
PYH3_k127_2590187_5 Belongs to the SfsA family K01892,K06206 - 6.1.1.21 0.00000000000000000000000000000007329 129.0
PYH3_k127_2590187_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0008565,GO:0009987,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016043,GO:0031224,GO:0031226,GO:0032977,GO:0033036,GO:0034613,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051205,GO:0051234,GO:0051641,GO:0061024,GO:0070727,GO:0071702,GO:0071705,GO:0071840,GO:0071944,GO:0072657,GO:0090150 - 0.00000000000000000000000009513 113.0
PYH3_k127_2590187_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000007081 75.0
PYH3_k127_2590187_8 MerR HTH family regulatory protein K18997 - - 0.00000000004978 68.0
PYH3_k127_2590187_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.000000001097 64.0
PYH3_k127_2597835_0 PFAM FMN-binding domain protein K19339 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004527 442.0
PYH3_k127_2597835_1 TraB family K09973 - - 0.0000000000000000000000000000000000000000000000000008421 193.0
PYH3_k127_2597835_2 - - - - 0.0000000000000000000000000000000000000000000002661 175.0
PYH3_k127_2597835_3 - - - - 0.000000000000005965 81.0
PYH3_k127_2628919_0 Homospermidine synthase K00808 - 2.5.1.44 1.624e-217 687.0
PYH3_k127_2628919_1 Spermine/spermidine synthase domain K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002184 272.0
PYH3_k127_2628919_2 aminopeptidase N K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000002169 254.0
PYH3_k127_2653219_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1469.0
PYH3_k127_2653219_1 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001295 263.0
PYH3_k127_2653219_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
PYH3_k127_2653219_3 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000009989 113.0
PYH3_k127_2653219_4 YCII-related domain K09780 - - 0.0000000006061 59.0
PYH3_k127_2654526_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 1.817e-207 653.0
PYH3_k127_2654526_1 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 288.0
PYH3_k127_2654526_2 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000001708 76.0
PYH3_k127_2656594_0 Phospholipase, patatin family K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006674 419.0
PYH3_k127_2656594_1 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000001403 136.0
PYH3_k127_2656594_2 Domain of Unknown Function (DUF748) - - - 0.0000000000000000000000000000004298 128.0
PYH3_k127_2656594_3 Polymer-forming cytoskeletal - - - 0.00000000000005592 73.0
PYH3_k127_2659995_0 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004242 459.0
PYH3_k127_2659995_1 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000001406 207.0
PYH3_k127_2664303_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009339 310.0
PYH3_k127_2664303_1 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000001406 191.0
PYH3_k127_2667459_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 1.668e-204 657.0
PYH3_k127_2668870_0 HNH nucleases - - - 0.00000000000000000000000000000000000000000000001097 177.0
PYH3_k127_2668870_1 - - - - 0.000000000000000000000000000000002363 138.0
PYH3_k127_2668870_2 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.000000000000000000000000000003363 128.0
PYH3_k127_2674028_0 rhodanese-related sulfurtransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000004587 222.0
PYH3_k127_2674028_1 protein histidine kinase activity K02660,K03406,K07716,K13924 - 2.1.1.80,2.7.13.3,3.1.1.61 0.00000000000000000000004119 108.0
PYH3_k127_2682115_0 PFAM multicopper oxidase type 2 K22350 - 1.16.3.3 0.0 1019.0
PYH3_k127_2682115_1 PFAM Bacterial pre-peptidase C-terminal domain - - - 0.00000000001922 78.0
PYH3_k127_268495_0 Iron-containing alcohol dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 610.0
PYH3_k127_268495_1 PFAM multicopper oxidase type 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 578.0
PYH3_k127_268495_2 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.000000000000000000000000000000000000000000000002934 174.0
PYH3_k127_268495_3 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000001446 153.0
PYH3_k127_2715256_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009788 465.0
PYH3_k127_2715256_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006922 333.0
PYH3_k127_2715256_2 Forms part of the polypeptide exit tunnel K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008607 307.0
PYH3_k127_2715256_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000001431 192.0
PYH3_k127_2715256_4 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000000000002402 155.0
PYH3_k127_2715256_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000001028 79.0
PYH3_k127_2721086_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 535.0
PYH3_k127_2721086_1 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 355.0
PYH3_k127_2721086_2 HAD-superfamily hydrolase, subfamily IA, variant 1 K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007995 297.0
PYH3_k127_2721086_3 - - - - 0.000001737 56.0
PYH3_k127_2729340_0 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 1.448e-281 871.0
PYH3_k127_2729340_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 382.0
PYH3_k127_2729340_2 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000003145 259.0
PYH3_k127_2729340_3 Protein of unknown function (DUF2905) - - - 0.000000000000000000000099 99.0
PYH3_k127_2738942_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.937e-265 822.0
PYH3_k127_2738942_1 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K07712 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005234 575.0
PYH3_k127_2738942_2 SMART ATP-binding region ATPase domain protein K07708 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 427.0
PYH3_k127_2738942_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002589 409.0
PYH3_k127_2738942_4 - - - - 0.0000000000001209 78.0
PYH3_k127_2738942_5 - - - - 0.000000000000278 81.0
PYH3_k127_2738942_6 Major facilitator Superfamily - - - 0.000000000002234 74.0
PYH3_k127_2740804_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001506 548.0
PYH3_k127_2740804_1 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000003217 186.0
PYH3_k127_2744125_0 FeS assembly protein SufB K09014 - - 5.252e-275 851.0
PYH3_k127_2744125_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002963 589.0
PYH3_k127_2744125_10 NnrU protein - - - 0.000000418 53.0
PYH3_k127_2744125_2 Uncharacterized protein family (UPF0051) K09015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 456.0
PYH3_k127_2744125_3 TIGRFAM FeS assembly ATPase SufC K09013 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006459 396.0
PYH3_k127_2744125_4 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 340.0
PYH3_k127_2744125_5 SUF system FeS assembly protein, NifU family K04488 - - 0.000000000000000000000000000000000000000000000000000000008604 203.0
PYH3_k127_2744125_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000001036 173.0
PYH3_k127_2744125_7 Rieske-like [2Fe-2S] domain K05710,K18087 - - 0.00000000000000000000000000000000000000006405 154.0
PYH3_k127_2744125_8 PaaD-like protein - - - 0.00000000000000000000000000000000000002592 146.0
PYH3_k127_2744125_9 Domain of unknown function (DUF1992) - - - 0.00000000000000000000000003005 122.0
PYH3_k127_2775604_0 Sodium:solute symporter family - - - 6.102e-284 889.0
PYH3_k127_2775604_1 Two-component sensor kinase N-terminal K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 482.0
PYH3_k127_2775604_2 Protein of unknown function, DUF485 - - - 0.000000000000000000000000000000000000000005619 157.0
PYH3_k127_2784539_0 Belongs to the malate synthase family K01638 - 2.3.3.9 5.902e-279 867.0
PYH3_k127_2784539_1 Lipoprotein releasing system transmembrane protein LolC K09808 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008104,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0033036,GO:0034613,GO:0044425,GO:0044459,GO:0044464,GO:0044872,GO:0044873,GO:0044874,GO:0051179,GO:0051641,GO:0070727,GO:0071944,GO:0072657,GO:0098796,GO:0098797 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002002 565.0
PYH3_k127_2784539_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005389 354.0
PYH3_k127_2784539_3 (ABC) transporter K05685,K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 301.0
PYH3_k127_2784539_4 Uncharacterized protein family UPF0016 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007522 244.0
PYH3_k127_2784539_5 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000003481 170.0
PYH3_k127_2789291_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0 1635.0
PYH3_k127_2789291_1 NADH:flavin oxidoreductase / NADH oxidase family K10680 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 304.0
PYH3_k127_2834587_0 protein synthesis factor, GTP-binding K06207 - - 1.358e-307 951.0
PYH3_k127_2845952_0 Transport of potassium into the cell K03549 - - 3.288e-273 853.0
PYH3_k127_2845952_1 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000053 151.0
PYH3_k127_286078_0 ATPase family associated with various cellular activities (AAA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 421.0
PYH3_k127_286078_1 Nudix N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002173 278.0
PYH3_k127_286078_2 lipid carrier protein - - - 0.0000000000000000000000000000000001716 136.0
PYH3_k127_2882208_0 Belongs to the peptidase S11 family K01286,K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005602 517.0
PYH3_k127_2882208_1 PFAM Aminotransferase, class IV K00824 - 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009233 445.0
PYH3_k127_2882208_2 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000003268 201.0
PYH3_k127_2882208_3 Protein of unknown function (DUF493) K09158 - - 0.0000000000000000000000000000001326 125.0
PYH3_k127_2898325_0 Bacterial membrane protein YfhO - - - 0.00000007367 65.0
PYH3_k127_2910010_0 4Fe-4S double cluster binding domain K11473 - - 0.00000000000000000000000000000000000000000000000006569 181.0
PYH3_k127_2910010_1 COG0695 Glutaredoxin and related proteins - - - 0.0000000000000000000000000000002785 129.0
PYH3_k127_2910010_2 SdpI/YhfL protein family - - - 0.000000000000000002185 96.0
PYH3_k127_2933345_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 1.254e-209 657.0
PYH3_k127_2933345_1 Helix-turn-helix type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 417.0
PYH3_k127_2933345_2 AAA ATPase central domain protein K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 380.0
PYH3_k127_2935873_0 Multicopper oxidase K22349 - 1.16.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 517.0
PYH3_k127_2935873_1 PFAM Metal-dependent phosphohydrolase, HD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000607 337.0
PYH3_k127_2935873_2 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 327.0
PYH3_k127_2950935_0 ribonuclease II K01147 - 3.1.13.1 2.444e-251 789.0
PYH3_k127_2950935_1 TIGRFAM TonB family protein K03832 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 319.0
PYH3_k127_2950935_2 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000001569 228.0
PYH3_k127_2950935_3 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000001967 175.0
PYH3_k127_2955947_0 pyruvate phosphate dikinase K01006 - 2.7.9.1 0.0 1428.0
PYH3_k127_2955947_1 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661 - 4.1.3.36 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000352 475.0
PYH3_k127_2955947_2 Divalent cation transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 471.0
PYH3_k127_2955947_3 benzoyl-CoA oxygenase K00528,K02641,K15511 - 1.14.13.208,1.18.1.2,1.19.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006046 383.0
PYH3_k127_2955947_4 Part of a membrane complex involved in electron transport K03617 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004005 293.0
PYH3_k127_2955947_5 - - - - 0.000000005706 59.0
PYH3_k127_2971106_0 Transport of potassium into the cell K03549 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006813,GO:0008150,GO:0008324,GO:0009987,GO:0015075,GO:0015077,GO:0015079,GO:0015318,GO:0015672,GO:0016020,GO:0022857,GO:0022890,GO:0030001,GO:0034220,GO:0046873,GO:0051179,GO:0051234,GO:0055085,GO:0071804,GO:0071805,GO:0098655,GO:0098660,GO:0098662 - 1.174e-234 735.0
PYH3_k127_2971106_1 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0000000000000000000000000000000000000000000000000000001891 197.0
PYH3_k127_2984854_0 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000004681 188.0
PYH3_k127_2984854_1 Phasin protein - - - 0.0000000000000000000000000000000000009384 145.0
PYH3_k127_2984854_2 Dioxygenase - - - 0.000000000000000000000003938 106.0
PYH3_k127_3010472_0 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001519 534.0
PYH3_k127_3010472_1 polysaccharide catabolic process - - - 0.000000000000000000000000000000008746 130.0
PYH3_k127_3042491_0 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002918 270.0
PYH3_k127_3042491_1 SOS response associated peptidase (SRAP) - - - 0.00000000000000000000000000000000000000000000000000000000001547 213.0
PYH3_k127_3042491_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000007422 180.0
PYH3_k127_3042491_3 Protein of unknown function (DUF3567) - - - 0.00000000001197 68.0
PYH3_k127_3045558_0 Malic enzyme K00029 - 1.1.1.40 0.0 1077.0
PYH3_k127_3045558_1 elongation factor G K02355 - - 5e-324 1005.0
PYH3_k127_3045558_10 - - - - 0.00000000000000000000000000000001337 128.0
PYH3_k127_3045558_11 Lipase maturation factor - - - 0.000000000000000000000000004047 117.0
PYH3_k127_3045558_12 - - - - 0.00000000000001998 80.0
PYH3_k127_3045558_13 Outer membrane lipoprotein K07285 - - 0.0005152 51.0
PYH3_k127_3045558_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008215 348.0
PYH3_k127_3045558_3 phosphoserine phosphatase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
PYH3_k127_3045558_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007972 284.0
PYH3_k127_3045558_5 Protein of unknown function, DUF599 - - - 0.000000000000000000000000000000000000000000000000000000000000003585 224.0
PYH3_k127_3045558_6 Cyclophilin-like K09143 - - 0.0000000000000000000000000000000000000000000000000007399 189.0
PYH3_k127_3045558_7 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000002265 153.0
PYH3_k127_3045558_8 Transglycosylase SLT domain - - - 0.00000000000000000000000000000000001151 144.0
PYH3_k127_3045558_9 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000008404 145.0
PYH3_k127_3046681_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000353 258.0
PYH3_k127_3046681_1 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000916 267.0
PYH3_k127_3046681_2 Metal-sensitive transcriptional repressor K21600 - - 0.000000000000000000000000000000001836 135.0
PYH3_k127_3046681_3 Heavy metal-associated domain protein K07213 - - 0.00000000000000000001244 93.0
PYH3_k127_310885_0 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 509.0
PYH3_k127_310885_1 coenzyme F390 K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006801 400.0
PYH3_k127_310885_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004526 352.0
PYH3_k127_310885_3 PFAM FecR protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000812 240.0
PYH3_k127_3122878_0 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002081 572.0
PYH3_k127_3122878_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003557 430.0
PYH3_k127_3122878_2 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007771 388.0
PYH3_k127_3146703_0 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 446.0
PYH3_k127_3146703_1 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003416 256.0
PYH3_k127_3146703_2 Prokaryotic N-terminal methylation motif - - - 0.00000000000000000000000000000000000000000000003852 180.0
PYH3_k127_3146703_3 - - - - 0.000000000000000000000000000000000000001803 161.0
PYH3_k127_3244942_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 7.57e-280 867.0
PYH3_k127_3244942_1 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.00000000000000000000000000000000000000000000000000000000000002124 219.0
PYH3_k127_3244942_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000003364 111.0
PYH3_k127_3249326_0 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006958 360.0
PYH3_k127_3249326_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008712 314.0
PYH3_k127_3249326_2 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000001956 252.0
PYH3_k127_3249326_3 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001089 254.0
PYH3_k127_3249326_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000173 206.0
PYH3_k127_3270084_0 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000008216 194.0
PYH3_k127_3270084_1 ThiS family K03636 - - 0.00000003376 61.0
PYH3_k127_3274633_0 mechanosensitive ion channel K03442 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 367.0
PYH3_k127_3274633_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000006069 220.0
PYH3_k127_3274633_2 Divalent cation transporter K06213 - - 0.000000000000000000000000000000000000000000000000115 182.0
PYH3_k127_329197_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001498 253.0
PYH3_k127_329197_1 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000000000000000000000004705 205.0
PYH3_k127_329197_2 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000003675 161.0
PYH3_k127_329197_3 Histidine kinase K19661 - 2.7.13.3 0.000000000000000000000000000000004146 140.0
PYH3_k127_3310865_0 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 578.0
PYH3_k127_3310865_1 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000002628 211.0
PYH3_k127_3310865_2 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.000000000000000000000007059 103.0
PYH3_k127_3314324_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 312.0
PYH3_k127_3314324_1 Belongs to the thioredoxin family K03671,K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000000000003606 181.0
PYH3_k127_3314324_2 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000003026 87.0
PYH3_k127_3314324_3 transcriptional regulator - - - 0.0000000000000004637 79.0
PYH3_k127_3322852_0 Cation transporter/ATPase, N-terminus - - - 6.12e-208 655.0
PYH3_k127_3324938_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 520.0
PYH3_k127_3324938_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 399.0
PYH3_k127_3337302_0 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008063 457.0
PYH3_k127_3337302_1 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007051 350.0
PYH3_k127_3337302_2 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000002603 261.0
PYH3_k127_3337302_3 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000001354 203.0
PYH3_k127_3337302_4 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.00000000000000000002304 107.0
PYH3_k127_3379514_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1230.0
PYH3_k127_3379514_1 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 1.594e-294 914.0
PYH3_k127_3379514_2 DAHP synthetase I family K01627 - 2.5.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002416 437.0
PYH3_k127_3379514_3 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001361 356.0
PYH3_k127_3379514_4 helix_turn_helix, cAMP Regulatory protein K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001507 266.0
PYH3_k127_3381523_0 Pfam Fatty acid - - - 0.0 1020.0
PYH3_k127_3381523_1 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 426.0
PYH3_k127_3381523_2 ABC transporter K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000111 417.0
PYH3_k127_3381523_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001165 289.0
PYH3_k127_3381523_4 Sodium Bile acid symporter family K03453 - - 0.000000000000000000000000000000000000002582 158.0
PYH3_k127_3394254_0 Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT K01499 - 3.5.4.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008095 413.0
PYH3_k127_3394254_1 COG0189 Glutathione synthase Ribosomal protein S6 modification enzyme (glutaminyl transferase) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000594 291.0
PYH3_k127_3425403_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004463 513.0
PYH3_k127_3425403_1 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000004212 242.0
PYH3_k127_3436017_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002448 587.0
PYH3_k127_3436017_1 Cytochrome P460 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002418 246.0
PYH3_k127_3436017_2 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000000000000001935 226.0
PYH3_k127_3440678_0 Acts as a magnesium transporter K06213 - - 2.61e-210 663.0
PYH3_k127_3440678_1 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000004244 209.0
PYH3_k127_3454538_0 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 462.0
PYH3_k127_3454538_1 Sodium/calcium exchanger protein K07301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 420.0
PYH3_k127_3454538_2 Sodium/hydrogen exchanger family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005057 317.0
PYH3_k127_3454538_3 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003346 248.0
PYH3_k127_3454538_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000322 120.0
PYH3_k127_3464368_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1162.0
PYH3_k127_3464368_1 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 237.0
PYH3_k127_3465329_0 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 340.0
PYH3_k127_3465329_1 COG0526 Thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000002777 136.0
PYH3_k127_3465329_2 Biopolymer transport protein K03559 - - 0.000000000000000000000000000001344 128.0
PYH3_k127_3481993_0 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 541.0
PYH3_k127_3481993_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 296.0
PYH3_k127_3481993_2 PFAM membrane protein of K08972 - - 0.0000000000000000000000000000000000000253 148.0
PYH3_k127_3492486_0 Sigma-54 interaction domain K07715 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009921 604.0
PYH3_k127_3492486_1 Belongs to the UPF0337 (CsbD) family - - - 0.000000776 55.0
PYH3_k127_3492486_2 - - - - 0.00005108 51.0
PYH3_k127_3493916_0 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007718 553.0
PYH3_k127_3493916_1 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 551.0
PYH3_k127_3493916_2 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000008489 109.0
PYH3_k127_351109_0 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 456.0
PYH3_k127_351109_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
PYH3_k127_351109_2 Belongs to the ABC transporter superfamily K06857 - 3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 291.0
PYH3_k127_351109_3 Histidine kinase K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004856 289.0
PYH3_k127_351109_4 - - - - 0.0000000000000000000000000000000000000007986 154.0
PYH3_k127_351109_5 PFAM TOBE domain protein - - - 0.000000000000000001779 87.0
PYH3_k127_3511514_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.461e-254 791.0
PYH3_k127_3511514_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 4.412e-194 611.0
PYH3_k127_3511514_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005533 522.0
PYH3_k127_3511514_3 Major facilitator Superfamily K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005449 466.0
PYH3_k127_3511514_4 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009413 403.0
PYH3_k127_3511514_5 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000757 360.0
PYH3_k127_3511514_6 pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000002109 148.0
PYH3_k127_3523137_0 PFAM MoeA domain protein domain I and II K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 540.0
PYH3_k127_3523137_1 Cytochrome c554 and c-prime - - - 0.0000000000000000000000000000000000000000000000008131 179.0
PYH3_k127_3523373_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 2.239e-208 677.0
PYH3_k127_3523373_1 cytochrome c biogenesis protein K07399 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008495 351.0
PYH3_k127_3530588_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002044 252.0
PYH3_k127_3530588_1 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000000000000001157 168.0
PYH3_k127_3530588_2 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000000000000000008235 150.0
PYH3_k127_3530588_3 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000000000001391 143.0
PYH3_k127_3530588_4 Belongs to the anti-sigma-factor antagonist family - - - 0.0000000000000000000000000431 116.0
PYH3_k127_3544809_0 von Willebrand factor, type A - - - 0.0 1188.0
PYH3_k127_3544809_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008293 567.0
PYH3_k127_3544809_2 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005373 499.0
PYH3_k127_3544809_3 CbbQ/NirQ/NorQ C-terminal K04748 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 488.0
PYH3_k127_3544809_4 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001751 267.0
PYH3_k127_3544809_5 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.000000000000000000000000000000000000000000000000000000000000006292 217.0
PYH3_k127_3544809_6 - - - - 0.000000000000000001754 91.0
PYH3_k127_3544809_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000001194 80.0
PYH3_k127_3557228_0 Large family of predicted nucleotide-binding domains K07175 - - 6.661e-253 785.0
PYH3_k127_3557228_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 493.0
PYH3_k127_3557228_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 415.0
PYH3_k127_3557228_3 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005467 326.0
PYH3_k127_3557228_4 PFAM lipolytic protein G-D-S-L family K10804 - 3.1.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000008748 267.0
PYH3_k127_3557228_5 PFAM Alkyl hydroperoxide reductase K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000007663 256.0
PYH3_k127_357216_0 Bacterial regulatory protein, Fis family K19641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 448.0
PYH3_k127_357216_1 NiFe/NiFeSe hydrogenase small subunit C-terminal K00534 - 1.12.7.2 0.000000000000000000000000000000000000000000000000001475 185.0
PYH3_k127_3586007_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1569.0
PYH3_k127_3586007_1 Sugar (and other) transporter - - - 5.996e-202 642.0
PYH3_k127_3586007_2 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000658 462.0
PYH3_k127_3586007_3 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000003315 216.0
PYH3_k127_3586007_4 MOFRL family K11529 - 2.7.1.165 0.0000000000000000002948 104.0
PYH3_k127_3614006_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1165.0
PYH3_k127_3614006_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0003674,GO:0003824,GO:0004365,GO:0005488,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0036094,GO:0043891,GO:0048037,GO:0050662,GO:0051287,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006954 595.0
PYH3_k127_3614006_2 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005123 539.0
PYH3_k127_3614006_3 Signal transduction histidine kinase - - - 0.0000000009356 60.0
PYH3_k127_3632529_0 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000000000000000000000000002892 241.0
PYH3_k127_3632529_1 Response regulator with CheY-like receiver, AAA-type ATPase, and DNA-binding domains - - - 0.0000000000000000000000000000000000000000000001188 180.0
PYH3_k127_3632529_2 Sigma-54 interaction domain - - - 0.00000000000004946 73.0
PYH3_k127_3636108_0 COG2202 FOG PAS PAC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002722 328.0
PYH3_k127_3636108_1 response regulator K11712 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005107 260.0
PYH3_k127_3636108_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000001328 112.0
PYH3_k127_3638214_0 Outer membrane efflux protein K18139 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 484.0
PYH3_k127_3638214_1 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000001598 200.0
PYH3_k127_3644826_0 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 600.0
PYH3_k127_3644826_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008598 347.0
PYH3_k127_3644826_2 peptidase U62, modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007273 335.0
PYH3_k127_3644826_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003661 244.0
PYH3_k127_3644826_4 protein secretion by the type IV secretion system K00564,K02026,K10716,K11070,K13924,K14393 - 2.1.1.172,2.1.1.80,3.1.1.61 0.000000000000000000000000000000000000000000000000000000000000002567 228.0
PYH3_k127_3695262_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000227 299.0
PYH3_k127_3695262_1 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000003347 194.0
PYH3_k127_3695262_2 Iron-sulphur cluster biosynthesis K13628 - - 0.000000000000000000000001799 108.0
PYH3_k127_372860_0 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 9.275e-202 632.0
PYH3_k127_372860_1 PFAM FAD linked oxidase domain protein K11472 - - 0.000000000000000000000000000005924 120.0
PYH3_k127_3737699_0 Belongs to the thiolase family K00632 - 2.3.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004158 594.0
PYH3_k127_3737699_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 570.0
PYH3_k127_3737699_2 3-hydroxyacyl-CoA dehydrogenase K07516 - 1.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 509.0
PYH3_k127_3737699_3 Long-chain fatty acid transport protein K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 368.0
PYH3_k127_3737699_4 amp-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004124 237.0
PYH3_k127_3737699_5 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
PYH3_k127_3749220_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1438.0
PYH3_k127_3749220_1 type II secretion system protein E K02454,K02652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003095 256.0
PYH3_k127_375223_0 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 357.0
PYH3_k127_3765361_0 Biotin-lipoyl like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003907 385.0
PYH3_k127_3765361_1 Outer membrane efflux protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001335 235.0
PYH3_k127_3765361_2 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000000001744 154.0
PYH3_k127_3765361_3 Outer membrane protein transport protein, Ompp1 FadL TodX K06076 - - 0.0000000009027 68.0
PYH3_k127_3770944_0 Domain of unknown function (DUF3400) - - - 0.0 1958.0
PYH3_k127_3770944_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002567 338.0
PYH3_k127_3770944_2 Protein of unknown function (DUF971) - - - 0.00000000000000000000000000000000000000000000000000000000001059 213.0
PYH3_k127_3770944_3 Histidine triad (Hit) protein - - - 0.000000000000000000000000000000000000000000000001285 177.0
PYH3_k127_3771691_0 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 422.0
PYH3_k127_3771691_1 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000136 262.0
PYH3_k127_3771691_2 Phosphoglycerate mutase family K15634 - 5.4.2.12 0.00003317 47.0
PYH3_k127_3800439_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.379e-263 822.0
PYH3_k127_3800439_1 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000005137 229.0
PYH3_k127_3800439_2 PFAM Sporulation domain protein - - - 0.000000000000000000000000000000000000000000000001118 180.0
PYH3_k127_3800439_3 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.000000000001289 68.0
PYH3_k127_3800439_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000005163 61.0
PYH3_k127_3825563_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 4.513e-267 832.0
PYH3_k127_3825563_1 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005982 365.0
PYH3_k127_3825563_2 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000002752 236.0
PYH3_k127_3832153_0 Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP K02837 - - 4.103e-253 791.0
PYH3_k127_3832153_1 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003687 236.0
PYH3_k127_3832153_2 Sulfur oxidation protein SoxY K17226 - - 0.00000000000000000000000000000001044 129.0
PYH3_k127_3832153_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000000000000000000000000000538 126.0
PYH3_k127_3832153_4 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000007236 118.0
PYH3_k127_3859722_0 Tellurite resistance protein TerB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 375.0
PYH3_k127_3859722_1 Belongs to the GST superfamily K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000007735 247.0
PYH3_k127_3859722_2 Ammonium transporter K03320,K06580 - - 0.0000000000000000000000007677 104.0
PYH3_k127_3859722_3 TIR domain - - - 0.000000000000001087 84.0
PYH3_k127_3867640_0 Formylmethanofuran dehydrogenase subunit A K00200 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0044237,GO:0044281 1.2.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 409.0
PYH3_k127_3867640_1 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 GO:0003674,GO:0003824,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0044281,GO:0071704 2.3.1.101 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 379.0
PYH3_k127_3869465_0 Belongs to the GPI family K01810 - 5.3.1.9 2.04e-266 828.0
PYH3_k127_3869465_1 TIGRFAM RND efflux system, outer membrane lipoprotein, NodT family K18139 - - 0.0000000000000000000000000000000000000000000001578 174.0
PYH3_k127_3869465_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000001559 92.0
PYH3_k127_3878640_0 Magnesium transport protein CorA - - - 3.854e-229 721.0
PYH3_k127_3878640_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001688 283.0
PYH3_k127_3878640_2 MOFRL family K11529 - 2.7.1.165 0.000000000000000000000000000000000000000000000000000000000000000007016 228.0
PYH3_k127_3878640_3 Phosphotransferase enzyme family - - - 0.0003927 49.0
PYH3_k127_3895557_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1124.0
PYH3_k127_3895557_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 1.523e-206 663.0
PYH3_k127_3895557_2 Periplasmic binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002319 303.0
PYH3_k127_3895557_3 protein SCO1 SenC PrrC involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000001926 218.0
PYH3_k127_3909547_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 5.9e-221 690.0
PYH3_k127_3909547_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006071 552.0
PYH3_k127_3909547_2 TIGRFAM squalene synthase HpnC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
PYH3_k127_3909547_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 353.0
PYH3_k127_3909547_4 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000003767 268.0
PYH3_k127_3909547_5 - - - - 0.0005122 52.0
PYH3_k127_3927889_0 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001398 379.0
PYH3_k127_3927889_1 PFAM Aminotransferase, class V K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000041 300.0
PYH3_k127_3927889_2 Iron-sulfur cluster assembly transcription factor IscR K13643 - - 0.000000000000000000000000000000000000000000000000000000000000001707 221.0
PYH3_k127_3927889_3 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000152 162.0
PYH3_k127_3933849_1 6-bladed beta-propeller - - - 0.000000000000000000000000000000008239 132.0
PYH3_k127_3938440_0 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 423.0
PYH3_k127_3938440_1 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003195 389.0
PYH3_k127_3938440_2 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2 K02806 - - 0.00000000000000000000000000000000000000000000000000000000000006683 218.0
PYH3_k127_3938440_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.000000000000000000000000000000000000000001366 156.0
PYH3_k127_3938440_4 sigma 54 modulation protein ribosomal protein S30EA K05808 - - 0.000000000000000000000000000000000000006426 152.0
PYH3_k127_3949907_0 Sulfate transporter antisigma-factor antagonist STAS - - - 6.065e-299 932.0
PYH3_k127_3949907_1 STAS domain K03321 - - 1.505e-231 733.0
PYH3_k127_3949907_2 Chromate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
PYH3_k127_3949907_3 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 323.0
PYH3_k127_3962348_0 Membrane transport protein K07088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 397.0
PYH3_k127_3962348_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) - - - 0.000000000000000000000000000000363 129.0
PYH3_k127_3962348_2 dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000002763 70.0
PYH3_k127_3966735_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1105.0
PYH3_k127_3966735_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 415.0
PYH3_k127_3966735_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000041 194.0
PYH3_k127_3966735_3 Peptidyl-prolyl cis-trans isomerase K03774 - 5.2.1.8 0.00000000000000000000000000002506 125.0
PYH3_k127_3997364_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.5e-281 878.0
PYH3_k127_4007609_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0 1009.0
PYH3_k127_4007609_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002158 395.0
PYH3_k127_4007609_2 - - - - 0.0008302 46.0
PYH3_k127_4014576_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1557.0
PYH3_k127_4014576_1 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 405.0
PYH3_k127_4014576_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 377.0
PYH3_k127_4014576_3 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.000000000000000000000000000000000000000000000003974 176.0
PYH3_k127_4014576_4 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000003018 173.0
PYH3_k127_4014576_5 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000958 164.0
PYH3_k127_4014576_6 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000000001434 132.0
PYH3_k127_4014576_7 Peptidase family M23 - - - 0.00004021 52.0
PYH3_k127_4107677_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 486.0
PYH3_k127_4107677_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 300.0
PYH3_k127_4107677_2 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.000000000000000000000000000000000000000008865 175.0
PYH3_k127_4173496_0 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 9.542e-225 704.0
PYH3_k127_4173496_1 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000007775 211.0
PYH3_k127_4173496_2 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000008011 178.0
PYH3_k127_4173496_3 Ribosomal protein S18 K02963 - - 0.000000000000000000000000000002383 120.0
PYH3_k127_4213592_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 605.0
PYH3_k127_4213592_1 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000007252 200.0
PYH3_k127_4213592_2 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000705 196.0
PYH3_k127_4213592_3 Hsp20/alpha crystallin family - - - 0.0000000000000000000000000000000000000000000003854 180.0
PYH3_k127_4213592_4 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000000000000000002591 149.0
PYH3_k127_4213592_5 Putative zinc-finger - - - 0.000000000001084 72.0
PYH3_k127_4213592_6 - - - - 0.00000001124 63.0
PYH3_k127_4235010_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002173 369.0
PYH3_k127_4235010_1 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000006344 209.0
PYH3_k127_4235010_2 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000007303 117.0
PYH3_k127_4238388_0 DAHP synthetase I family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007228 595.0
PYH3_k127_4238388_1 Transcriptional regulator, Crp Fnr family - - - 0.0000000000000000000000000000005046 128.0
PYH3_k127_4280296_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000256 505.0
PYH3_k127_4280296_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 419.0
PYH3_k127_4280296_2 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000005483 181.0
PYH3_k127_4290040_0 Male sterility - - - 5.132e-284 887.0
PYH3_k127_4290040_1 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 402.0
PYH3_k127_4290040_2 Bacterial transcriptional repressor - - - 0.00000000000000000000000000000000000009046 146.0
PYH3_k127_4290040_3 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000000004819 138.0
PYH3_k127_4290040_4 Poly(hydroxyalcanoate) granule associated protein (phasin) - - - 0.00000000000000000000000000003032 136.0
PYH3_k127_4309167_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1150.0
PYH3_k127_4309167_1 Periplasmic binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006503 298.0
PYH3_k127_4309167_2 ABC-type amino acid transport signal transduction systems periplasmic component domain K10001 GO:0003333,GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0006835,GO:0006836,GO:0006855,GO:0006865,GO:0008150,GO:0015711,GO:0015740,GO:0015800,GO:0015807,GO:0015813,GO:0015849,GO:0015893,GO:0016595,GO:0016597,GO:0030288,GO:0030313,GO:0031406,GO:0031975,GO:0034220,GO:0036094,GO:0042221,GO:0042493,GO:0042597,GO:0043167,GO:0043168,GO:0043177,GO:0044464,GO:0046942,GO:0050896,GO:0051179,GO:0051234,GO:0055085,GO:0070335,GO:0070778,GO:0071702,GO:0071705,GO:0098656,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000003835 237.0
PYH3_k127_4333696_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.202e-226 705.0
PYH3_k127_4333696_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.293e-214 674.0
PYH3_k127_4333696_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 353.0
PYH3_k127_4340100_0 COG0412 Dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003774 427.0
PYH3_k127_4340100_1 Peptidyl-prolyl cis-trans K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000001041 185.0
PYH3_k127_4357584_0 acyl-CoA dehydrogenase K06445 - - 6.611e-313 972.0
PYH3_k127_4357584_1 Acyl-CoA dehydrogenase N terminal K20035 - - 5.701e-259 810.0
PYH3_k127_4357584_2 electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000003703 227.0
PYH3_k127_4357584_3 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000004159 224.0
PYH3_k127_4386880_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003143 447.0
PYH3_k127_4386880_1 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 400.0
PYH3_k127_4386880_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 356.0
PYH3_k127_4386880_3 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 325.0
PYH3_k127_4386880_4 TIGRFAM cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005344 318.0
PYH3_k127_4386880_5 PFAM acyl-coA-binding protein, ACBP - - - 0.00000000000000000000000002484 111.0
PYH3_k127_4417822_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 550.0
PYH3_k127_4417822_1 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005406 351.0
PYH3_k127_4417822_2 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 290.0
PYH3_k127_4417822_3 NlpC/P60 family - - - 0.0000000000000000000000000000000000000000000000001592 182.0
PYH3_k127_4417822_4 Belongs to the UPF0145 family - - - 0.000000000000000000000000000000000000000113 156.0
PYH3_k127_4427367_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K06281 - 1.12.99.6 5.222e-320 986.0
PYH3_k127_4427367_1 PFAM Cysteine-rich - - - 6.584e-218 713.0
PYH3_k127_4427367_2 NiFe/NiFeSe hydrogenase small subunit C-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 521.0
PYH3_k127_4427367_3 nitrate reductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000004178 220.0
PYH3_k127_4427367_4 - - - - 0.000000000000008436 77.0
PYH3_k127_4427367_5 glycolate oxidase subunit GlcD - - - 0.0000000000000615 75.0
PYH3_k127_4437189_0 Enoyl-(Acyl carrier protein) reductase K00059,K00076 - 1.1.1.100,1.1.1.159 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 313.0
PYH3_k127_4437189_1 Belongs to the 'phage' integrase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 305.0
PYH3_k127_4437189_2 ErfK YbiS YcfS YnhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002973 248.0
PYH3_k127_4437189_3 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.00000000000000000000000000000000000000000000000000000000000000004652 226.0
PYH3_k127_4437189_4 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000005322 241.0
PYH3_k127_4437189_5 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000001203 205.0
PYH3_k127_4437189_6 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000001446 154.0
PYH3_k127_4437189_7 Belongs to the 'phage' integrase family - - - 0.00000000006531 63.0
PYH3_k127_4455115_0 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 292.0
PYH3_k127_4455115_1 probably involved in intracellular septation K06190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000054 259.0
PYH3_k127_4455115_2 YCII-related domain K09780 - - 0.0000000000000000000000000138 119.0
PYH3_k127_4455229_0 MASE1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 312.0
PYH3_k127_4455229_1 Flagellar regulatory protein FleQ - - - 0.000000000000000000000000000000000004686 150.0
PYH3_k127_4463851_0 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.83e-253 784.0
PYH3_k127_4463851_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.101e-235 744.0
PYH3_k127_4463851_2 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 4.053e-215 672.0
PYH3_k127_4463851_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 327.0
PYH3_k127_4463851_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
PYH3_k127_4463851_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000002122 244.0
PYH3_k127_4521270_0 Belongs to the glycosyl hydrolase 57 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 529.0
PYH3_k127_4521270_1 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0000000000000000000000000000000000000000000000000000000000000601 216.0
PYH3_k127_4531577_0 Domain of unknown function (DUF3329) K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 381.0
PYH3_k127_4531577_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000004288 190.0
PYH3_k127_4531577_2 Transcriptional regulatory protein, C terminal K07657 - - 0.000000000000000000000000000002555 122.0
PYH3_k127_4533165_0 Amp-dependent synthetase and ligase K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 354.0
PYH3_k127_4533165_1 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 333.0
PYH3_k127_4561301_0 SMART Elongator protein 3 MiaB NifB K09711 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 493.0
PYH3_k127_4561301_1 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 292.0
PYH3_k127_4561301_2 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000000000004977 211.0
PYH3_k127_4561301_3 DsrE/DsrF-like family K07092 - - 0.0000000000000000000000000000000000000000000000002649 179.0
PYH3_k127_4561301_4 lipoate-protein ligase A K03800 - 6.3.1.20 0.00000000000000000000000000000000000000000002391 164.0
PYH3_k127_4561301_5 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000007935 138.0
PYH3_k127_4561301_6 Rhodanese Homology Domain - - - 0.0000000000000000000000000002589 117.0
PYH3_k127_4561301_7 PFAM DMSO reductase anchor subunit (DmsC) K21309 - - 0.000000000000000000000005707 102.0
PYH3_k127_4564933_0 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 1.898e-200 637.0
PYH3_k127_4590686_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 1.42e-242 754.0
PYH3_k127_4590686_1 Belongs to the peptidase S1C family K04771 - 3.4.21.107 1.476e-204 648.0
PYH3_k127_4590686_2 COG0526 Thiol-disulfide isomerase and thioredoxins K00384 - 1.8.1.9 0.000000000000000000004211 96.0
PYH3_k127_4606595_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1371.0
PYH3_k127_4606595_1 UvrD REP K03657 - 3.6.4.12 0.0 1011.0
PYH3_k127_4606595_2 PFAM Phosphoribulokinase uridine kinase K00855 - 2.7.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003007 480.0
PYH3_k127_4606595_3 TIGRFAM cation diffusion facilitator family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002972 409.0
PYH3_k127_4606595_4 Belongs to the pseudouridine synthase RsuA family K06182 - 5.4.99.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002363 391.0
PYH3_k127_4606595_5 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000006078 250.0
PYH3_k127_4606595_6 - - - - 0.0000000000000000000000000000000000000000004858 167.0
PYH3_k127_4606595_7 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000006542 147.0
PYH3_k127_464517_0 TIGRFAM Formylmethanofuran dehydrogenase, subunit A K00200 - 1.2.7.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 560.0
PYH3_k127_464517_1 formylmethanofuran dehydrogenase activity K00202 GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0044237,GO:0044281 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004364 272.0
PYH3_k127_464517_2 Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT) K00672 - 2.3.1.101 0.0000000000000000000000000000000000000009194 151.0
PYH3_k127_4740345_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007868 556.0
PYH3_k127_4740345_1 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000227 237.0
PYH3_k127_4740345_2 Ribosomal protein S9/S16 K02996 - - 0.0000000000000000000000000000000000000000000000000000000009928 203.0
PYH3_k127_4740345_3 Required for insertion of 4Fe-4S clusters K15724 - - 0.0000000000000000000000000000000000000000000000000000009448 201.0
PYH3_k127_4740345_4 - - - - 0.0000000000000000000000000000000000000000000000000001242 194.0
PYH3_k127_4740345_5 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000000000000000000000000001183 182.0
PYH3_k127_4740345_6 DUF218 domain - - - 0.0000000000000000000000000000000000001082 148.0
PYH3_k127_4740345_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000305 77.0
PYH3_k127_4742941_0 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 616.0
PYH3_k127_4742941_1 PFAM Zinc iron permease K16267 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 362.0
PYH3_k127_4742941_2 - - - - 0.0000000001057 66.0
PYH3_k127_4772458_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 578.0
PYH3_k127_4772458_1 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000002591 107.0
PYH3_k127_4787894_0 B12 binding domain K00548 - 2.1.1.13 0.0 1718.0
PYH3_k127_4787894_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 420.0
PYH3_k127_4787894_2 Belongs to the pseudouridine synthase RsuA family K06181 - 5.4.99.20 0.0000000000000000000000000000000000000000001901 160.0
PYH3_k127_4794033_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 1268.0
PYH3_k127_4809095_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1154.0
PYH3_k127_4809095_1 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 5.47e-298 923.0
PYH3_k127_4809095_10 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000000000005587 151.0
PYH3_k127_4809095_11 Prokaryotic N-terminal methylation motif K02650 - - 0.0000000000000000000000004558 110.0
PYH3_k127_4809095_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 5.913e-295 923.0
PYH3_k127_4809095_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01120 - 3.1.4.17 1.707e-220 733.0
PYH3_k127_4809095_4 COG0626 Cystathionine beta-lyases cystathionine gamma-synthases K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 569.0
PYH3_k127_4809095_5 peptidase m48, ste24p - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 508.0
PYH3_k127_4809095_6 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 391.0
PYH3_k127_4809095_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002006 238.0
PYH3_k127_4809095_8 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000001016 224.0
PYH3_k127_4809095_9 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000007614 195.0
PYH3_k127_4814254_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 565.0
PYH3_k127_4814254_1 Belongs to the peptidase M48B family K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 407.0
PYH3_k127_4814254_2 Histidine kinase K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005594 371.0
PYH3_k127_4814254_3 Alpha beta hydrolase K00433 - 1.11.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000004924 251.0
PYH3_k127_4835662_0 - - - - 0.000000000000000000000000000002832 123.0
PYH3_k127_4835662_1 Transcriptional regulator - - - 0.00000000000000008817 84.0
PYH3_k127_4835662_2 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000008283 72.0
PYH3_k127_4835662_3 - - - - 0.0000001649 59.0
PYH3_k127_4835662_4 Beta-lactamase - - - 0.00014 47.0
PYH3_k127_4848786_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007229 565.0
PYH3_k127_4848786_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 444.0
PYH3_k127_4848786_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009225 330.0
PYH3_k127_4848786_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000007735 72.0
PYH3_k127_4859137_0 hemolysin iii K11068 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 289.0
PYH3_k127_4859137_1 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000001049 230.0
PYH3_k127_4859137_2 - - - - 0.0002146 48.0
PYH3_k127_4860357_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 1.001e-204 643.0
PYH3_k127_4860357_1 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 417.0
PYH3_k127_4860357_2 Short-chain dehydrogenase reductase SDR K00059,K03793 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008667,GO:0009058,GO:0009237,GO:0009238,GO:0009239,GO:0009712,GO:0009713,GO:0009987,GO:0016043,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0018958,GO:0019184,GO:0019290,GO:0019438,GO:0019540,GO:0019748,GO:0022607,GO:0034641,GO:0042802,GO:0043043,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044550,GO:0046189,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 316.0
PYH3_k127_4860357_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002422 266.0
PYH3_k127_4860357_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003007 263.0
PYH3_k127_4860357_5 Large-conductance mechanosensitive channel, MscL K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.000000000000000000000000000000000000000000000000000000000000007891 220.0
PYH3_k127_4860357_6 Rhodanese-like domain - - - 0.000000000000000000000000000799 125.0
PYH3_k127_4860357_7 Bacterial SH3 domain - - - 0.000000008694 59.0
PYH3_k127_4872369_0 TIGRFAM ferredoxin-type protein, NapH MauN family K02574 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 450.0
PYH3_k127_4872369_1 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000000000000000001025 144.0
PYH3_k127_487517_0 Glycosyltransferase like family K07011 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 312.0
PYH3_k127_487517_1 epimerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002338 264.0
PYH3_k127_4901232_0 Putative diguanylate phosphodiesterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 400.0
PYH3_k127_4901232_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005607 366.0
PYH3_k127_4920184_0 Polysaccharide biosynthesis protein - - - 2.535e-255 799.0
PYH3_k127_4956315_0 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000001532 237.0
PYH3_k127_4956315_1 redox protein, regulator of disulfide bond formation - - - 0.00000000000000000000000000000000000000000000007438 172.0
PYH3_k127_4956315_2 methyltransferase activity - - - 0.000000000000000000000000000000005086 134.0
PYH3_k127_4964294_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 383.0
PYH3_k127_4964294_1 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002383 340.0
PYH3_k127_4964294_2 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 323.0
PYH3_k127_4964294_3 plastoquinol--plastocyanin reductase activity - - - 0.0000000000000000000000000000000001711 134.0
PYH3_k127_4964667_0 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 2.633e-226 707.0
PYH3_k127_4964667_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 420.0
PYH3_k127_4964667_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.00000000000000000000000000000000000000000000000002117 180.0
PYH3_k127_4964667_3 - - - - 0.000000000000000003142 100.0
PYH3_k127_4964667_4 - - - - 0.00000000461 58.0
PYH3_k127_4964787_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 6.912e-287 891.0
PYH3_k127_4964787_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002644 419.0
PYH3_k127_4964787_2 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005836 367.0
PYH3_k127_4964787_3 protein complex oligomerization - GO:0001539,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006928,GO:0006950,GO:0006974,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0019897,GO:0019898,GO:0031234,GO:0033554,GO:0040011,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0048870,GO:0050896,GO:0051179,GO:0051674,GO:0051716,GO:0071944,GO:0071973,GO:0071978,GO:0097588,GO:0098552,GO:0098562 - 0.0000000000000000000000000000000000000000000002905 179.0
PYH3_k127_4964787_5 Anti-anti-sigma regulatory factor (Antagonist of anti-sigma factor) K17763 - - 0.00007625 54.0
PYH3_k127_5022086_0 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005653 448.0
PYH3_k127_5022086_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001966 279.0
PYH3_k127_5047363_0 Sulphur oxidation protein SoxZ K17226 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 348.0
PYH3_k127_5047363_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009177 325.0
PYH3_k127_505029_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 6.437e-219 688.0
PYH3_k127_505029_1 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000000002278 232.0
PYH3_k127_505029_2 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000007601 89.0
PYH3_k127_5065529_0 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 306.0
PYH3_k127_5065529_1 TIGRFAM Phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 293.0
PYH3_k127_5065529_2 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000001826 242.0
PYH3_k127_5070623_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1423.0
PYH3_k127_5070623_1 FecR protein - - - 0.000004541 57.0
PYH3_k127_510716_0 Nitronate monooxygenase K00459 - 1.13.12.16 6.932e-224 701.0
PYH3_k127_510716_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 563.0
PYH3_k127_510716_2 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 391.0
PYH3_k127_510716_3 - - - - 0.0000002164 56.0
PYH3_k127_510716_4 Membrane-bound lysozyme-inhibitor of c-type lysozyme - - - 0.0006269 47.0
PYH3_k127_5116063_0 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 337.0
PYH3_k127_5116063_1 SpoIIAA-like - - - 0.000000000000000000000000000000000000006911 153.0
PYH3_k127_5116063_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000000000000003137 101.0
PYH3_k127_5176419_0 AMP-binding enzyme C-terminal domain - - - 4.51e-237 744.0
PYH3_k127_5176419_1 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000003243 228.0
PYH3_k127_5176419_2 Ion channel - - - 0.0000000000000002405 88.0
PYH3_k127_520180_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 3.592e-251 784.0
PYH3_k127_520180_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 395.0
PYH3_k127_520180_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001089 323.0
PYH3_k127_520180_3 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.000000000000000000000000000000000000000000000000000000000000000001797 229.0
PYH3_k127_520180_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.00000000000003256 73.0
PYH3_k127_520180_5 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000000000004456 77.0
PYH3_k127_5211389_0 Cysteine-rich domain - - - 2.95e-228 717.0
PYH3_k127_5211389_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001811 282.0
PYH3_k127_5211389_2 Protein of unknown function (DUF3501) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002431 268.0
PYH3_k127_5211389_3 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006119 265.0
PYH3_k127_5211389_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000002537 214.0
PYH3_k127_5226539_0 aminopeptidase N K01256 - 3.4.11.2 2.251e-267 834.0
PYH3_k127_5226539_1 Divalent cation transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000002734 232.0
PYH3_k127_5226539_2 - - - - 0.0000000000000000000000000000000000000001052 169.0
PYH3_k127_5227146_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.237e-224 699.0
PYH3_k127_5227146_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 464.0
PYH3_k127_5227146_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 374.0
PYH3_k127_5227146_3 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000005877 271.0
PYH3_k127_5227146_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000009884 83.0
PYH3_k127_5261609_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 374.0
PYH3_k127_5261609_1 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001855 270.0
PYH3_k127_5261609_2 DNA polymerase III, delta' K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000001148 224.0
PYH3_k127_5273893_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.242e-260 815.0
PYH3_k127_5273893_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002403 263.0
PYH3_k127_5273893_2 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000003183 190.0
PYH3_k127_5273893_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000006179 111.0
PYH3_k127_5315093_0 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 323.0
PYH3_k127_5315093_1 response regulator K07684 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 312.0
PYH3_k127_5315093_2 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.000005453 57.0
PYH3_k127_5336835_0 response - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003889 301.0
PYH3_k127_539999_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006668 612.0
PYH3_k127_539999_1 Protein of unknown function (DUF465) K09794 - - 0.000000006148 63.0
PYH3_k127_5404573_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008993 518.0
PYH3_k127_5404573_1 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 473.0
PYH3_k127_5404573_2 Glutamine amidotransferase of anthranilate synthase K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005513 327.0
PYH3_k127_5404573_3 PIN domain - - - 0.00000000000000000000000000000000000000000000009327 172.0
PYH3_k127_5404573_4 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000000003339 155.0
PYH3_k127_5404573_5 positive regulation of growth K01081 - 3.1.3.5 0.00000000000000000000000001165 110.0
PYH3_k127_5404573_6 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000003598 107.0
PYH3_k127_5406953_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family - - - 5.483e-261 812.0
PYH3_k127_5406953_1 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 1.168e-227 721.0
PYH3_k127_5406953_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009617 409.0
PYH3_k127_5406953_3 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000004232 211.0
PYH3_k127_5406953_4 Addiction module toxin RelE StbE family - - - 0.00000000000000000000000000000442 127.0
PYH3_k127_5406953_5 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000002041 78.0
PYH3_k127_5406953_6 protein conserved in bacteria K03690 - - 0.000000001415 61.0
PYH3_k127_5426896_0 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
PYH3_k127_5426896_1 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000001303 143.0
PYH3_k127_5426896_2 SpoIIAA-like - - - 0.00000000000000000000000000000000002158 138.0
PYH3_k127_5426896_3 Protein of unknown function (DUF3106) - - - 0.00002855 51.0
PYH3_k127_5448154_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006087 488.0
PYH3_k127_5466410_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000875 610.0
PYH3_k127_5466410_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009809 468.0
PYH3_k127_5466410_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 478.0
PYH3_k127_5466410_3 integral membrane protein - - - 0.0000000000000000000002388 97.0
PYH3_k127_5466410_4 Predicted integral membrane protein (DUF2269) - - - 0.00000000004248 67.0
PYH3_k127_5466410_5 integral membrane protein - - - 0.00002196 47.0
PYH3_k127_5467202_0 Binding-protein-dependent transport system inner membrane component K02054,K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 384.0
PYH3_k127_5467202_1 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000001312 159.0
PYH3_k127_5467202_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.0000000000000001943 79.0
PYH3_k127_550852_0 cytochrome - - - 1.679e-254 795.0
PYH3_k127_550852_1 4Fe-4S single cluster domain - - - 8.715e-226 703.0
PYH3_k127_550852_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 563.0
PYH3_k127_550852_3 transcriptional regulator AsnC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006628 254.0
PYH3_k127_550852_4 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000000000000000000000000000000004706 207.0
PYH3_k127_550852_5 overlaps another CDS with the same product name - - - 0.000000000000000000000000000000000000000000000000000003418 196.0
PYH3_k127_5542953_0 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 436.0
PYH3_k127_5542953_1 serine threonine protein kinase K11912,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000003449 225.0
PYH3_k127_5542953_2 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000753 167.0
PYH3_k127_557316_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1052.0
PYH3_k127_557316_1 Thermostable hemolysin - - - 0.000000000000000000000000000000000000000000001508 173.0
PYH3_k127_557316_2 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.000000000000000000000000000000000000000000009103 163.0
PYH3_k127_557316_3 CHAD - - - 0.0000004965 54.0
PYH3_k127_558585_0 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 467.0
PYH3_k127_558585_1 Belongs to the hyi family K01816 - 5.3.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 405.0
PYH3_k127_558585_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 304.0
PYH3_k127_558585_3 FAD linked oxidases, C-terminal domain K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 0.0000000000000000000000001621 109.0
PYH3_k127_5586097_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1065.0
PYH3_k127_5586097_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001093 567.0
PYH3_k127_5586097_2 TIGRFAM phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 420.0
PYH3_k127_5586097_3 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005155 259.0
PYH3_k127_5586097_4 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000009482 229.0
PYH3_k127_5586097_5 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000000000006447 197.0
PYH3_k127_5586097_6 Protein of unknown function (DUF541) - - - 0.00000000000000000000000000002592 127.0
PYH3_k127_5586097_7 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000000006835 94.0
PYH3_k127_55991_0 Poly-beta-hydroxybutyrate K03821 - - 6.723e-212 673.0
PYH3_k127_55991_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 5.66e-211 665.0
PYH3_k127_55991_2 TrkA-N domain protein K03499 - - 7.984e-205 647.0
PYH3_k127_55991_3 Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001794 226.0
PYH3_k127_55991_4 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000000000002247 198.0
PYH3_k127_55991_5 PFAM CheW domain protein K02659 - - 0.000000000000000000000000000000000000000000004014 171.0
PYH3_k127_55991_6 Inositol-1-monophosphatase K01082,K01092 - 3.1.3.25,3.1.3.7 0.0000000000000000000000000000000000000000004994 159.0
PYH3_k127_5649928_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 396.0
PYH3_k127_5649928_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008134 406.0
PYH3_k127_5649928_2 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005972 249.0
PYH3_k127_566490_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 3.006e-198 647.0
PYH3_k127_566490_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005429 314.0
PYH3_k127_566490_2 - - - - 0.0000000000000000000001172 104.0
PYH3_k127_566490_3 Glycine-zipper domain - - - 0.00000000000000002059 84.0
PYH3_k127_5677182_0 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 556.0
PYH3_k127_5677182_1 - - - - 0.000000003827 60.0
PYH3_k127_5710839_0 Peptidase, M50 family K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000156 445.0
PYH3_k127_5710839_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 316.0
PYH3_k127_5710839_2 membrane K02451,K03832,K13735,K20276,K21449 - - 0.0000004958 55.0
PYH3_k127_5744299_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 1.24e-249 783.0
PYH3_k127_5744299_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.062e-196 617.0
PYH3_k127_5744299_2 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006793 545.0
PYH3_k127_5744299_3 PFAM Methionine biosynthesis MetW - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 303.0
PYH3_k127_5744299_4 system, fructose subfamily IIA component K02821 - 2.7.1.194 0.00000000000000000000000000000000000000000000000001033 183.0
PYH3_k127_5744299_5 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000002387 156.0
PYH3_k127_5744299_6 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000003956 136.0
PYH3_k127_5744299_7 - - - - 0.000000000000000000000000000000008954 132.0
PYH3_k127_5744299_8 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000002347 92.0
PYH3_k127_577899_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0 1043.0
PYH3_k127_577899_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 4.107e-301 928.0
PYH3_k127_577899_10 TIGRFAM pyruvate ketoisovalerate oxidoreductase, gamma subunit K00172,K18357 - 1.2.1.58,1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 296.0
PYH3_k127_577899_11 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001168 261.0
PYH3_k127_577899_12 4Fe-4S dicluster domain K18930 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001731 273.0
PYH3_k127_577899_2 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 2.458e-219 687.0
PYH3_k127_577899_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K18356 - 1.2.1.58,1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004957 576.0
PYH3_k127_577899_4 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 454.0
PYH3_k127_577899_5 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005425 410.0
PYH3_k127_577899_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
PYH3_k127_577899_7 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 383.0
PYH3_k127_577899_8 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 362.0
PYH3_k127_577899_9 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 392.0
PYH3_k127_5837077_0 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 379.0
PYH3_k127_5837077_1 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 359.0
PYH3_k127_5837077_2 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000829 327.0
PYH3_k127_5837077_3 Glyoxalase K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000001698 236.0
PYH3_k127_5837077_4 Rubredoxin - - - 0.0000000000000000000000007224 118.0
PYH3_k127_5837077_5 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.0000000000000006607 81.0
PYH3_k127_5837077_6 Lactoylglutathione lyase K01759 - 4.4.1.5 0.00000002274 59.0
PYH3_k127_5988214_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000252 400.0
PYH3_k127_5988214_1 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000002764 239.0
PYH3_k127_5988214_2 PFAM periplasmic binding protein K02016 - - 0.00000000009453 63.0
PYH3_k127_5989356_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 0.0 1065.0
PYH3_k127_5989356_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.985e-235 732.0
PYH3_k127_5989356_2 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.0000000000006473 69.0
PYH3_k127_5989356_3 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.000000003769 61.0
PYH3_k127_5992934_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 9.013e-223 696.0
PYH3_k127_5992934_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 312.0
PYH3_k127_5992934_2 haloacid dehalogenase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001146 244.0
PYH3_k127_6013444_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 531.0
PYH3_k127_6013444_1 - - - - 0.0000000000000000000000000000000004636 138.0
PYH3_k127_6018946_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 567.0
PYH3_k127_6018946_1 Glycosyl transferase family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 412.0
PYH3_k127_6018946_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 344.0
PYH3_k127_6018946_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000151 225.0
PYH3_k127_6018946_4 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000000000001636 208.0
PYH3_k127_6018946_5 Heparinase II/III N-terminus - - - 0.000000000000000000000000000000000000000000000000000000001755 213.0
PYH3_k127_60362_0 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 432.0
PYH3_k127_60362_1 Bacterial SH3 domain - - - 0.000000000000000000000000000000000000000001591 161.0
PYH3_k127_6045654_0 DNA polymerase X family K02347 - - 1.544e-256 802.0
PYH3_k127_6045654_1 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000000000005802 143.0
PYH3_k127_6045654_2 gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000002149 139.0
PYH3_k127_6050141_0 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 7.482e-229 712.0
PYH3_k127_6050141_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008799 338.0
PYH3_k127_6050141_2 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 315.0
PYH3_k127_6050141_3 Peptidase M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 303.0
PYH3_k127_6050141_4 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004952 262.0
PYH3_k127_6051418_0 MotA TolQ ExbB proton channel K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002481 320.0
PYH3_k127_6051418_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000004635 187.0
PYH3_k127_6051418_2 Biopolymer transport protein ExbD TolR K03560 - - 0.000000000000000000000000000000000000000000000002408 187.0
PYH3_k127_6051418_3 4-hydroxybenzoyl-CoA thioesterase K07107 - - 0.000000000000000000000000000000000000000002703 164.0
PYH3_k127_6051418_4 TolA C-terminal K03646 - - 0.00000000004033 72.0
PYH3_k127_6062792_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 552.0
PYH3_k127_6062792_1 6-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000001175 240.0
PYH3_k127_6070031_0 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006239 608.0
PYH3_k127_6070031_1 PFAM AMMECR1 domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002849 233.0
PYH3_k127_6070031_2 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000002072 150.0
PYH3_k127_6104568_0 serine threonine protein kinase K12132 - 2.7.11.1 1.429e-312 978.0
PYH3_k127_6104568_1 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008117 360.0
PYH3_k127_6104568_2 (FHA) domain - - - 0.00000000000000000000000000000000000000000000001254 173.0
PYH3_k127_6122645_0 TonB-dependent receptor K02014 - - 1.041e-216 702.0
PYH3_k127_6122645_1 Lactonase, 7-bladed beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 385.0
PYH3_k127_6122645_2 Transcriptional activator of acetoin glycerol metabolism K21405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003359 275.0
PYH3_k127_6122645_3 PFAM response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003938 261.0
PYH3_k127_6122645_4 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001831 262.0
PYH3_k127_6122645_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000009152 199.0
PYH3_k127_6122645_6 Cytochrome b/b6/petB - - - 0.0000000000000000000000000000000000000000000000000001168 192.0
PYH3_k127_6122645_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000004232 51.0
PYH3_k127_612621_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 9.327e-283 875.0
PYH3_k127_612621_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.458e-278 868.0
PYH3_k127_612621_10 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000000002549 199.0
PYH3_k127_612621_11 PFAM PemK family protein K07171 - - 0.000000000000000000000000000000000000000004182 160.0
PYH3_k127_612621_12 - - - - 0.0000000000000000000000000000000000008742 141.0
PYH3_k127_612621_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 GO:0003674,GO:0003824,GO:0005215,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0008324,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015075,GO:0015077,GO:0015078,GO:0015318,GO:0015399,GO:0015405,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016021,GO:0016462,GO:0016469,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0019829,GO:0022804,GO:0022853,GO:0022857,GO:0022890,GO:0031224,GO:0032991,GO:0033177,GO:0034220,GO:0034641,GO:0034654,GO:0036442,GO:0042623,GO:0042625,GO:0042626,GO:0043492,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0044769,GO:0045259,GO:0045263,GO:0046034,GO:0046390,GO:0046483,GO:0046933,GO:0046961,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0090662,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:0099131,GO:0099132,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000309 138.0
PYH3_k127_612621_14 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000002506 129.0
PYH3_k127_612621_15 Transcriptional regulator antitoxin, MazE K07172 - - 0.00000000000002891 75.0
PYH3_k127_612621_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.049e-267 829.0
PYH3_k127_612621_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 6.394e-207 651.0
PYH3_k127_612621_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 557.0
PYH3_k127_612621_5 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009771 432.0
PYH3_k127_612621_6 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004459 391.0
PYH3_k127_612621_7 Belongs to the ParB family K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001008 255.0
PYH3_k127_612621_8 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000000000000000008326 203.0
PYH3_k127_612621_9 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000002339 190.0
PYH3_k127_6146879_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 565.0
PYH3_k127_6146879_1 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000002661 199.0
PYH3_k127_6146879_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000006941 150.0
PYH3_k127_6146879_3 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.0000000000000000000000000000002113 124.0
PYH3_k127_6173188_0 Malic enzyme K00029 - 1.1.1.40 0.0 1044.0
PYH3_k127_6210179_0 Belongs to the short-chain dehydrogenases reductases (SDR) family K05886,K16066 - 1.1.1.276,1.1.1.381 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 322.0
PYH3_k127_6210179_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 288.0
PYH3_k127_6210179_2 Thioredoxin K07396 - - 0.0000000000000000000000000000000000000000002706 174.0
PYH3_k127_6213772_0 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 389.0
PYH3_k127_6213772_1 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000000000000177 128.0
PYH3_k127_6213772_2 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000003021 89.0
PYH3_k127_6215154_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008203 378.0
PYH3_k127_6215154_1 Copper resistance protein D - - - 0.0000000000000000000000000000000000000000000000000000005582 196.0
PYH3_k127_6220190_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 2.48e-253 787.0
PYH3_k127_6220190_1 Lipocalin-like domain - - - 0.0000000000000000000000000000000006509 132.0
PYH3_k127_6220190_2 - - - - 0.00000000000000000003934 94.0
PYH3_k127_6221120_0 Predicted membrane protein (DUF2207) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 464.0
PYH3_k127_6221120_1 PFAM LemA family K03744 - - 0.00000000000000000000000000002342 119.0
PYH3_k127_6250396_0 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006131 372.0
PYH3_k127_6250396_1 Phage integrase family - - - 0.00000000000000000000000000000000000000006801 168.0
PYH3_k127_6264256_0 Outer membrane protein beta-barrel family - - - 1.613e-206 653.0
PYH3_k127_6283277_0 Bacterial periplasmic substrate-binding proteins K10001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
PYH3_k127_6283277_1 ABC-type polar amino acid transport system, ATPase component K10004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 411.0
PYH3_k127_6283277_2 Binding-protein-dependent transport system inner membrane component K02029,K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001008 331.0
PYH3_k127_6283277_3 Binding-protein-dependent transport system inner membrane component K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006364 319.0
PYH3_k127_6283277_4 Protein of unknown function (DUF456) K09793 - - 0.00000000000000000000000000000000000000000004957 168.0
PYH3_k127_6283277_5 Catalyzes the alpha,beta-elimination reaction of D- cysteine and of several D-cysteine derivatives. It could be a defense mechanism against D-cysteine K05396,K17950 - 4.4.1.15,4.4.1.25 0.0000000000000000000000000001278 116.0
PYH3_k127_6283277_6 Serine aminopeptidase, S33 - - - 0.000000000000000000000000002963 113.0
PYH3_k127_6283730_0 ATPase associated with various cellular activities, AAA_5 K04748 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 436.0
PYH3_k127_6283730_1 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 350.0
PYH3_k127_6283730_2 TPM domain K08988 - - 0.00000000000000000000000000000000000000003851 154.0
PYH3_k127_6332923_0 TIGRFAM Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 426.0
PYH3_k127_6332923_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003157 419.0
PYH3_k127_6332923_2 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.000000000000000000000000000000000000000000000000000000000000005999 219.0
PYH3_k127_6332923_3 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.000000000000000000000000000000000000000000000005727 186.0
PYH3_k127_6332923_4 phosphoribosyl-ATP diphosphatase activity K01523 - 3.6.1.31 0.00000000000000000000000000000000000000009941 153.0
PYH3_k127_6332923_5 CobB/CobQ-like glutamine amidotransferase domain K02501 - - 0.000000000000000000000000000000000000001712 148.0
PYH3_k127_6332923_6 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000002653 118.0
PYH3_k127_6332923_7 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.000000000000000000000003504 108.0
PYH3_k127_6350780_0 L,D-transpeptidase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 425.0
PYH3_k127_6350780_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000003038 259.0
PYH3_k127_6350780_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009502 261.0
PYH3_k127_6350780_3 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.00000000000000000000000000000000000000000000000000000005068 202.0
PYH3_k127_6399395_0 Involved in the TonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 578.0
PYH3_k127_6399395_1 Cell division and transport-associated protein TolA K03646 - - 0.000000000000000000000000000000000007831 143.0
PYH3_k127_6400542_0 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 535.0
PYH3_k127_6400542_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006401 276.0
PYH3_k127_6400542_2 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005131 256.0
PYH3_k127_6421534_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 9.619e-209 658.0
PYH3_k127_6427985_0 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 6.189e-269 833.0
PYH3_k127_6427985_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003189 564.0
PYH3_k127_6427985_2 4Fe-4S single cluster domain K18006 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 370.0
PYH3_k127_6427985_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 319.0
PYH3_k127_6427985_4 membrane protein (DUF2238) K08984 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005706 267.0
PYH3_k127_6427985_5 Poly(R)-hydroxyalkanoic acid synthase, class III, PhaC subunit K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009058,GO:0016234,GO:0042618,GO:0042619,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464,GO:0070088,GO:0071704,GO:1901440,GO:1901441,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000004512 244.0
PYH3_k127_6427985_6 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000007576 234.0
PYH3_k127_6427985_7 maturation - - - 0.0000000000000000000000000000000000000000000009241 171.0
PYH3_k127_6427985_8 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.000000000000000000000000000000000000000000947 165.0
PYH3_k127_6427985_9 Protein of unknown function (DUF504) - - - 0.00000000000000000003838 101.0
PYH3_k127_6431465_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1011.0
PYH3_k127_6431465_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 3.427e-194 617.0
PYH3_k127_6431465_2 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 579.0
PYH3_k127_6431465_3 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 513.0
PYH3_k127_6431465_4 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006245 454.0
PYH3_k127_6431465_5 ABC-type branched-chain amino acid transport systems, ATPase component K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002661 437.0
PYH3_k127_6431465_6 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008466 419.0
PYH3_k127_6431465_7 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 384.0
PYH3_k127_6431465_8 PFAM 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002212 385.0
PYH3_k127_6431465_9 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00007287 49.0
PYH3_k127_6454499_0 Response regulator receiver K07714,K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003869 598.0
PYH3_k127_6454499_1 PFAM Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 536.0
PYH3_k127_6454499_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000002447 106.0
PYH3_k127_6454499_3 Sel1-like repeats. K07126 - - 0.000000000000001363 86.0
PYH3_k127_645815_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 372.0
PYH3_k127_645815_1 PIN domain - - - 0.000000000000000000000000000000000005473 145.0
PYH3_k127_6488708_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.943e-265 824.0
PYH3_k127_6488708_1 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006184 502.0
PYH3_k127_6488708_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009145 477.0
PYH3_k127_6488708_3 Pfam:Pyridox_oxidase - - - 0.0000000000000000000000000000000000000000000002872 171.0
PYH3_k127_6488708_4 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000002254 128.0
PYH3_k127_6489656_0 Heavy metal transport detoxification protein K17686,K19597 - 3.6.3.54 1.514e-221 697.0
PYH3_k127_6489656_1 Trypsin K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001758 542.0
PYH3_k127_6489656_2 Histidine kinase A domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004148 295.0
PYH3_k127_6489656_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002224 258.0
PYH3_k127_6489656_4 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000833 249.0
PYH3_k127_6489656_5 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000005514 171.0
PYH3_k127_6489656_6 Cold-shock DNA-binding domain protein K03704 - - 0.000000000000000000000000000000001169 131.0
PYH3_k127_6489656_7 Protein of unknown function (DUF3460) - - - 0.0000000000003698 73.0
PYH3_k127_6513650_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 5.867e-230 719.0
PYH3_k127_6513650_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 327.0
PYH3_k127_6513650_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000865 240.0
PYH3_k127_6513650_3 helix_turn_helix, Arsenical Resistance Operon Repressor K03892 - - 0.0000000000000000000000000009255 120.0
PYH3_k127_6519496_0 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 317.0
PYH3_k127_6519496_1 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K00042 - 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000001285 213.0
PYH3_k127_6519496_2 - - - - 0.000000000000000000000000000001446 128.0
PYH3_k127_6522428_0 abc transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 428.0
PYH3_k127_6522428_1 MlaD protein K02067 - - 0.00000000000000000000000000000000000000000000000000000007389 206.0
PYH3_k127_6542885_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.925e-308 952.0
PYH3_k127_6542885_1 alpha beta hydrolase fold K03821 - - 1.051e-236 743.0
PYH3_k127_6542885_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 4.426e-195 612.0
PYH3_k127_6542885_3 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003567 321.0
PYH3_k127_6542885_4 PFAM Endonuclease exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000002633 241.0
PYH3_k127_6542885_5 NUDIX domain K08310 - 3.6.1.67 0.00000000000000000000000000000000000000000000000000000000244 205.0
PYH3_k127_6542885_6 Putative regulatory protein - - - 0.00000000000000000000000000001192 121.0
PYH3_k127_6542885_7 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000001761 116.0
PYH3_k127_6565202_0 belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002776 452.0
PYH3_k127_6565202_1 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007847 313.0
PYH3_k127_6565202_2 PFAM cytochrome c, class I K08738 - - 0.0000000001854 70.0
PYH3_k127_6565202_3 SAF K00003 - 1.1.1.3 0.000000002194 59.0
PYH3_k127_6565202_4 PFAM cytochrome c, class I K08738 - - 0.000000003721 66.0
PYH3_k127_6571891_0 Protein of unknown function (DUF3141) - - - 0.0 1032.0
PYH3_k127_6571891_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 508.0
PYH3_k127_6571891_2 phosphate K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 460.0
PYH3_k127_6571891_3 - - - - 0.00000000000000002774 87.0
PYH3_k127_6571891_4 - - - - 0.000000002622 63.0
PYH3_k127_6578918_0 deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K11645 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 568.0
PYH3_k127_6578918_1 Diguanylate cyclase K02488 - 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 307.0
PYH3_k127_6581995_0 Periplasmic lysozyme inhibitor of I-type lysozyme - - - 0.0000000000000000000000000001757 125.0
PYH3_k127_6581995_1 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000001046 89.0
PYH3_k127_6581995_2 PFAM HPP family protein K07168 - - 0.000000000000009422 78.0
PYH3_k127_6581995_3 - - - - 0.0000000000008255 72.0
PYH3_k127_6588328_0 pfkB family carbohydrate kinase K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 490.0
PYH3_k127_6588328_1 COG1368 Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily K01002 - 2.7.8.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 455.0
PYH3_k127_6588328_2 17 kDa surface antigen K06077 - - 0.000004706 51.0
PYH3_k127_6593215_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003496 505.0
PYH3_k127_6593215_1 Belongs to the UPF0758 family K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003551 294.0
PYH3_k127_6593215_2 Ribosomal L28 family K02902 - - 0.000000000000000000000000000000001255 132.0
PYH3_k127_6593215_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 0.0000000000000000000000000000001285 125.0
PYH3_k127_6593215_4 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.000000000000000002148 90.0
PYH3_k127_6593215_5 Desaturase K00507 - 1.14.19.1 0.0000000000000001757 87.0
PYH3_k127_6607628_0 MBOAT, membrane-bound O-acyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 505.0
PYH3_k127_6607628_1 - - - - 0.000000000000000000000000000000000000000000000000000000000007907 231.0
PYH3_k127_6629351_0 sulfide dehydrogenase K05301 - 1.8.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009833 514.0
PYH3_k127_6629351_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000002479 192.0
PYH3_k127_6629351_2 Protein of Unknown function (DUF2784) - - - 0.00000000000000000000000000000000000005352 149.0
PYH3_k127_6629351_3 cytochrome - - - 0.000000000001839 70.0
PYH3_k127_664937_0 argininosuccinate lyase K01755 - 4.3.2.1 1.238e-228 716.0
PYH3_k127_664937_1 Histidine kinase K08082 - 2.7.13.3 0.000000000001533 73.0
PYH3_k127_6683775_0 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 339.0
PYH3_k127_6683775_1 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000001976 151.0
PYH3_k127_6683775_2 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.0000000000000000144 87.0
PYH3_k127_669720_0 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 454.0
PYH3_k127_669720_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 311.0
PYH3_k127_669720_2 Tetrapyrrole (Corrin/Porphyrin) Methylases K07056 - 2.1.1.198 0.0000000000000000000000000000000000000000000000000000000000000000000000000006849 262.0
PYH3_k127_669720_3 HAD-superfamily hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000004832 256.0
PYH3_k127_669720_4 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000003999 182.0
PYH3_k127_669720_5 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000002447 132.0
PYH3_k127_6715014_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 451.0
PYH3_k127_6715014_1 - - - - 0.000000000000000000000000000000003408 133.0
PYH3_k127_6715014_2 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00001857 47.0
PYH3_k127_6731929_0 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001129 260.0
PYH3_k127_6731929_1 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000003692 194.0
PYH3_k127_6731929_2 DDE superfamily endonuclease K07494 - - 0.000000001775 61.0
PYH3_k127_6739277_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006336 539.0
PYH3_k127_6739277_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 397.0
PYH3_k127_6787468_0 3-beta hydroxysteroid dehydrogenase/isomerase family K08678 - 4.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008734 554.0
PYH3_k127_6787468_1 PFAM Glycosyl transferase family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 325.0
PYH3_k127_6787468_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003906 308.0
PYH3_k127_6787468_3 GtrA-like protein - - - 0.000000000000000000000000178 112.0
PYH3_k127_6799492_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 573.0
PYH3_k127_6799492_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
PYH3_k127_6799492_2 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000007803 189.0
PYH3_k127_6799492_3 Trypsin - - - 0.0000000000000000000000000000000000000000000000004805 193.0
PYH3_k127_6799492_4 - - - - 0.00000000000000000000000000000000000000001651 160.0
PYH3_k127_6799492_5 DsrC like protein - - - 0.00000000000000000000000000000000000000002531 157.0
PYH3_k127_6799492_6 Uncharacterized conserved protein (DUF2249) - - - 0.000000000000000000000000000000000000904 145.0
PYH3_k127_6799492_7 Protein of unknown function (DUF2892) - - - 0.0000000000000000000000003768 109.0
PYH3_k127_6799492_8 Bacterial protein of unknown function (DUF853) K06915 - - 0.0000000000000000000001739 98.0
PYH3_k127_6799492_9 PFAM Cyclic nucleotide-binding - - - 0.000000000000000000361 93.0
PYH3_k127_680473_0 Isocitrate/isopropylmalate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 567.0
PYH3_k127_680473_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006876 517.0
PYH3_k127_680473_2 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002143 463.0
PYH3_k127_680473_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 454.0
PYH3_k127_680473_4 Protein of unknown function DUF47 K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002787 273.0
PYH3_k127_680473_5 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000007174 263.0
PYH3_k127_680473_6 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000003811 220.0
PYH3_k127_680473_7 Protein of unknown function (DUF2788) - - - 0.000000000000000000000006778 102.0
PYH3_k127_680473_8 - - - - 0.0000004668 61.0
PYH3_k127_6815457_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 2.573e-201 637.0
PYH3_k127_6815457_1 peptidase - - - 0.0000000000000000000000001655 108.0
PYH3_k127_684575_0 ABC transporter - - - 3.312e-292 904.0
PYH3_k127_684575_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 1.407e-265 832.0
PYH3_k127_684575_2 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 374.0
PYH3_k127_684575_3 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000005104 253.0
PYH3_k127_684575_4 PilZ domain K02676 - - 0.00000000000000000000000000000000000000000000003272 172.0
PYH3_k127_684575_5 Ankyrin repeat K06867 - - 0.0000000000000000000000000000000000000000000001369 176.0
PYH3_k127_684575_6 protein conserved in bacteria - - - 0.0000000000000000000000000002291 121.0
PYH3_k127_684575_7 Tautomerase enzyme K01821 - 5.3.2.6 0.0000000000000000000000000011 115.0
PYH3_k127_684575_8 UreE urease accessory protein, C-terminal domain K21929 - 3.2.2.27 0.00000000000000003745 81.0
PYH3_k127_684575_9 TIGRFAM DNA polymerase III, delta prime subunit K02341 - 2.7.7.7 0.0000000001717 63.0
PYH3_k127_6946281_0 PFAM ABC-1 domain protein K03688 - - 2.384e-248 777.0
PYH3_k127_6946281_1 Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K18005 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.00000000000000000000000000000000000000000000000000000000000001403 222.0
PYH3_k127_6946281_2 - - - - 0.000000000000000000000000000000000000000000000000000005079 197.0
PYH3_k127_6946281_3 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000002222 184.0
PYH3_k127_6971715_0 Protein of unknown function (DUF3422) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009471 463.0
PYH3_k127_6971715_1 Belongs to the UPF0502 family K09915 - - 0.0000000000000000000000000000000000000000000000000000000000000001762 232.0
PYH3_k127_6971715_2 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000000000006888 168.0
PYH3_k127_6971715_3 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000003504 85.0
PYH3_k127_6979977_0 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000007065 169.0
PYH3_k127_6979977_1 - - - - 0.000000000000000000000000000000000000000001338 172.0
PYH3_k127_6979977_2 YMGG-like Gly-zipper - - - 0.000000000000000000000000004748 119.0
PYH3_k127_6979977_3 - - - - 0.000000000000000001499 89.0
PYH3_k127_7003047_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004347 401.0
PYH3_k127_7003047_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004306 325.0
PYH3_k127_7003047_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 284.0
PYH3_k127_7003047_3 ApaG domain - - - 0.000000000000000000000000000000000000000000000000000000006919 200.0
PYH3_k127_7003047_4 ubiE/COQ5 methyltransferase family K00570 - 2.1.1.17,2.1.1.71 0.00000525 50.0
PYH3_k127_7009481_0 Cytochrome c oxidase subunit III K02276,K02299 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 399.0
PYH3_k127_7009481_1 PFAM Cytochrome c oxidase assembly protein CtaG Cox11 K02258 - - 0.000000000000000000000000000000000000000000001596 168.0
PYH3_k127_7020158_0 PFAM ATPase associated with various cellular activities, AAA_3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 480.0
PYH3_k127_7020158_1 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000003338 133.0
PYH3_k127_7044934_0 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002135 300.0
PYH3_k127_7044934_1 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000006193 182.0
PYH3_k127_7044934_2 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.00000000000000001188 83.0
PYH3_k127_7045_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.224e-224 702.0
PYH3_k127_7045_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 553.0
PYH3_k127_7045_2 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000001661 229.0
PYH3_k127_7052972_0 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005436 462.0
PYH3_k127_7052972_1 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000009324 168.0
PYH3_k127_7061774_0 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 367.0
PYH3_k127_7061774_1 Caspase domain - - - 0.00000000000000000000000000000000000000002972 156.0
PYH3_k127_7062633_0 methyltransferase - - - 3.611e-194 616.0
PYH3_k127_7062633_1 NAD dependent epimerase dehydratase family K19180 - 1.1.1.339 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 309.0
PYH3_k127_7062633_2 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K00067,K01790 - 1.1.1.133,5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000154 255.0
PYH3_k127_7062633_3 - - - - 0.00000000000000000000000000000000000000000005781 173.0
PYH3_k127_7062633_4 Polysaccharide biosynthesis protein K01709 - 4.2.1.45 0.0000000000000002848 79.0
PYH3_k127_7065149_0 TRANSFER OF ELECTRONS FROM NADH TO THE RESPIRATORY CHAIN. THE IMMEDIATE ELECTRON ACCEPTOR FOR THE ENZYME IS BELIEVED TO BE UBIQUINONE. DOES NOT COUPLE THE REDOX REACTION TO PROTON TRANSLOCATION. Interpro FAD-dependent pyridine K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001306 572.0
PYH3_k127_7065149_1 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 363.0
PYH3_k127_7065149_2 Polyketide cyclase / dehydrase and lipid transport - - - 0.0000000000000000000000000000000000000000000000000000000000000000002442 248.0
PYH3_k127_7067054_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 295.0
PYH3_k127_7067054_1 LemA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000841 280.0
PYH3_k127_7067054_2 Cytochrome b561 K12262 - - 0.0000000000000000000000000000000000000000000000000000000000000000004481 233.0
PYH3_k127_7067054_3 Belongs to the UPF0312 family - - - 0.00000000000000000000000000000000000000000000000000000000006896 212.0
PYH3_k127_7067054_4 Belongs to the UPF0312 family - - - 0.0000000000000000001326 89.0
PYH3_k127_7068034_0 extracellular solute-binding protein - - - 0.0 1028.0
PYH3_k127_7068034_1 Peptidyl-prolyl cis-trans isomerase K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 598.0
PYH3_k127_7068034_2 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005124 520.0
PYH3_k127_7068034_3 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001387 429.0
PYH3_k127_7068034_4 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000001792 197.0
PYH3_k127_7068034_5 bacterial (prokaryotic) histone like domain K03530 - - 0.0000000000000000000000000000002566 125.0
PYH3_k127_7068034_6 - - - - 0.00000000004237 65.0
PYH3_k127_7071797_0 ABC transporter transmembrane region K06147 - - 2.927e-303 938.0
PYH3_k127_7071797_1 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 606.0
PYH3_k127_7071797_2 Methyltransferase K18911 - 2.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004854 349.0
PYH3_k127_7071797_3 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 345.0
PYH3_k127_7071797_4 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 308.0
PYH3_k127_7071797_5 Beta-lactamase enzyme family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002568 307.0
PYH3_k127_7071797_6 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000005978 145.0
PYH3_k127_7071797_7 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 0.00000002041 57.0
PYH3_k127_7092196_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 469.0
PYH3_k127_7092196_1 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006449 447.0
PYH3_k127_7092196_2 tellurite resistance protein - - - 0.000000000000000000000000000000000000000000000000000000000000193 216.0
PYH3_k127_7092196_3 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000002281 169.0
PYH3_k127_7092196_4 MarC family integral membrane protein - - - 0.00000000000000000000000000000000000001978 149.0
PYH3_k127_7099852_0 Cytochrome b(N-terminal)/b6/petB - - - 1.96e-253 797.0
PYH3_k127_7099852_1 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008896 318.0
PYH3_k127_7099852_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003773 288.0
PYH3_k127_7099852_3 PFAM electron transport protein SCO1 SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001618 262.0
PYH3_k127_7099852_4 - - - - 0.0000000000000000000000000000000000000003371 155.0
PYH3_k127_7109362_0 acetyltransferase - - - 0.00000000000000000000000000000000000003334 149.0
PYH3_k127_7109362_1 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.00000000000000000000000000000000004971 138.0
PYH3_k127_7109362_2 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.000000000000000000000000005167 121.0
PYH3_k127_711789_0 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1005.0
PYH3_k127_711789_1 dihydroorotase K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000004942 218.0
PYH3_k127_711789_2 Pfam Glutaredoxin - - - 0.000000000000000000000000000001461 141.0
PYH3_k127_7121100_0 PFAM Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005506 323.0
PYH3_k127_7121100_1 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000000000000000000000000000000001124 240.0
PYH3_k127_7121100_2 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.000000000002419 68.0
PYH3_k127_7130026_0 Tripartite tricarboxylate transporter TctA family K07793 - - 6.552e-256 796.0
PYH3_k127_7130026_1 AMP-binding enzyme C-terminal domain K18661 - - 2.818e-207 655.0
PYH3_k127_7130026_10 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003109 254.0
PYH3_k127_7130026_11 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000003318 160.0
PYH3_k127_7130026_12 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.00000000000000000000000000008933 132.0
PYH3_k127_7130026_2 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 578.0
PYH3_k127_7130026_3 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008162 544.0
PYH3_k127_7130026_4 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003804 527.0
PYH3_k127_7130026_5 Tripartite tricarboxylate transporter family receptor K07795 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006493 486.0
PYH3_k127_7130026_6 2-dehydropantoate 2-reductase K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 463.0
PYH3_k127_7130026_7 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 379.0
PYH3_k127_7130026_8 membrane transporter protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 347.0
PYH3_k127_7130026_9 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 345.0
PYH3_k127_7133631_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 2.42e-208 655.0
PYH3_k127_7133631_1 phosphate starvation-inducible protein PhoH K06217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 325.0
PYH3_k127_7133631_2 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 K03185 - - 0.00000000000000000000000000000000000000000000006274 174.0
PYH3_k127_7135477_0 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001149 275.0
PYH3_k127_7135477_1 COG2755 Lysophospholipase L1 and related esterases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006129 261.0
PYH3_k127_7141204_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006849 482.0
PYH3_k127_7141204_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002664 411.0
PYH3_k127_7141204_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001762 283.0
PYH3_k127_7179421_0 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000003181 217.0
PYH3_k127_7179421_1 - - - - 0.000000000000000000000000001036 125.0
PYH3_k127_7193577_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 3.63e-237 741.0
PYH3_k127_7193577_1 PFAM permease YjgP YjgQ family protein K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 369.0
PYH3_k127_7193577_2 Permease, YjgP YjgQ family K11720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 342.0
PYH3_k127_7193577_3 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000118 199.0
PYH3_k127_7227231_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 529.0
PYH3_k127_7227231_1 L-cysteine cystine lyase K04127,K11325 - 5.1.1.17 0.0000000000000000000000000000000000000002822 166.0
PYH3_k127_7227231_2 Telomere recombination K07566 - 2.7.7.87 0.000000002313 58.0
PYH3_k127_7235947_0 membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K05685 - - 2.102e-239 762.0
PYH3_k127_7235947_1 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 585.0
PYH3_k127_7235947_10 Resolvase, N terminal domain - - - 0.000000001134 65.0
PYH3_k127_7235947_11 - - - - 0.0003573 49.0
PYH3_k127_7235947_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007895 472.0
PYH3_k127_7235947_3 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006746 408.0
PYH3_k127_7235947_4 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003888 373.0
PYH3_k127_7235947_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 330.0
PYH3_k127_7235947_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 320.0
PYH3_k127_7235947_7 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.000000000000000000000000000000000000000000000000000000000000000000000244 251.0
PYH3_k127_7235947_8 Protein of unknown function (DUF1318) K09978 - - 0.000000000000000000000000000000000000000000000000001049 190.0
PYH3_k127_7235947_9 - - - - 0.0000000001393 64.0
PYH3_k127_7240639_0 Flavocytochrome c sulphide dehydrogenase, flavin-binding K17218,K17229 - 1.8.2.3,1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001578 459.0
PYH3_k127_7240639_1 Histone deacetylase domain - - - 0.00000001339 56.0
PYH3_k127_7240639_2 response to hydrogen peroxide K08985 - - 0.0000001592 61.0
PYH3_k127_7292333_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000001572 231.0
PYH3_k127_7292333_1 COG2515 1-aminocyclopropane-1-carboxylate deaminase K05396,K17950 - 4.4.1.15,4.4.1.25 0.00000000000000000000000000000000000000000000000000000000000000002443 230.0
PYH3_k127_7292333_2 - - - - 0.000000000000004295 84.0
PYH3_k127_7301115_0 Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate K08289 - 2.1.2.2 7.078e-207 650.0
PYH3_k127_7301115_1 Glycine zipper - - - 0.00000000000000000000000000000000000000000000000000000003133 203.0
PYH3_k127_7301115_2 - - - - 0.0000000000000000000000000000000000007623 139.0
PYH3_k127_7301115_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000002963 123.0
PYH3_k127_7315238_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 491.0
PYH3_k127_7315238_1 (ABC) transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 397.0
PYH3_k127_7315238_2 NADH dehydrogenase K03885 - 1.6.99.3 0.000000004935 59.0
PYH3_k127_7318820_0 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000004742 226.0
PYH3_k127_7318820_1 Protein of unknown function (DUF3301) - - - 0.0000000000000000009257 99.0
PYH3_k127_7336726_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1011.0
PYH3_k127_7336726_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 1.5e-323 997.0
PYH3_k127_7336726_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 313.0
PYH3_k127_7336726_3 Planctomycete cytochrome C - - - 0.0000000000000000000000000000001809 128.0
PYH3_k127_7336726_4 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000002591 76.0
PYH3_k127_7336726_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000128 88.0
PYH3_k127_7358013_0 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001075 271.0
PYH3_k127_7358013_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000003467 199.0
PYH3_k127_7358013_2 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000000000000000000000001031 218.0
PYH3_k127_7358013_3 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000003377 157.0
PYH3_k127_7380119_0 Von Willebrand factor A K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 598.0
PYH3_k127_7380119_1 AAA domain (Cdc48 subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000003232 235.0
PYH3_k127_7380119_2 FR47-like protein - - - 0.000000000000000000000000000000000000000000006053 168.0
PYH3_k127_7380119_3 diguanylate cyclase - - - 0.000000000000000000000000000000003566 134.0
PYH3_k127_7380395_0 24 kD subunit K00122 - 1.17.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 510.0
PYH3_k127_7380395_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000006831 96.0
PYH3_k127_738485_0 Neisseria PilC beta-propeller domain K02674 - - 0.0 1067.0
PYH3_k127_738485_1 Type IV Pilus-assembly protein W K02672 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 302.0
PYH3_k127_738485_10 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000001177 80.0
PYH3_k127_738485_2 Major facilitator Superfamily K06902 - - 0.0000000000000000000000000000000000000000000000000000000000008403 215.0
PYH3_k127_738485_3 Belongs to the Fur family K09826 - - 0.00000000000000000000000000000000000000000000000004183 182.0
PYH3_k127_738485_4 Pilus assembly protein PilX - - - 0.000000000000000000000000000000000000000004284 175.0
PYH3_k127_738485_5 Type II transport protein GspH K08084 - - 0.00000000000000000000000000000000001109 143.0
PYH3_k127_738485_6 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000000000004627 139.0
PYH3_k127_738485_7 CBS domain - - - 0.0000000000000000000000000000002324 134.0
PYH3_k127_738485_8 type IV pilus modification protein PilV K02671 - - 0.00000000000000000000000000001849 126.0
PYH3_k127_738485_9 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.000000000000000000000000005082 113.0
PYH3_k127_7393585_0 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 515.0
PYH3_k127_7393585_1 Cytochrome C oxidase, cbb3-type, subunit III K17222 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003201 439.0
PYH3_k127_7393585_2 phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001564 248.0
PYH3_k127_7393585_3 COG1335 Amidases related to nicotinamidase - - - 0.0000000000000000000000000000000000000000000000000002934 193.0
PYH3_k127_7405248_0 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 327.0
PYH3_k127_7405248_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000006723 125.0
PYH3_k127_7405248_2 amine dehydrogenase activity - - - 0.00000000000000003446 94.0
PYH3_k127_7407501_0 Patatin-like phospholipase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000887 545.0
PYH3_k127_7407501_1 Mechanosensitive ion channel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002274 336.0
PYH3_k127_7439426_0 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000711 498.0
PYH3_k127_7439426_1 HAD-superfamily hydrolase, subfamily IA, variant 3 K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 295.0
PYH3_k127_7439426_2 Bacterial regulatory proteins, tetR family K05501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 282.0
PYH3_k127_7470342_0 protein containing a von Willebrand factor type A (vWA) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 412.0
PYH3_k127_7470342_1 Peptidoglycan-binding domain 1 protein K02450,K03791,K17733 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001279 384.0
PYH3_k127_7470342_2 Sigma-54 interaction domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 299.0
PYH3_k127_7476454_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 536.0
PYH3_k127_7476454_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000001519 169.0
PYH3_k127_7476778_0 COG0834 ABC-type amino acid transport signal transduction systems, periplasmic component domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 382.0
PYH3_k127_7476778_1 PFAM glutamate synthase alpha subunit K00202 - 1.2.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000005713 252.0
PYH3_k127_7476778_2 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000177 254.0
PYH3_k127_7476778_3 - - - - 0.0000000000000000000000000000000000000000000000000000006431 203.0
PYH3_k127_7476778_4 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000002771 154.0
PYH3_k127_7476778_5 Cytochrome c - - - 0.00000000000000000000000000003808 132.0
PYH3_k127_7476778_6 PQQ-like domain - - - 0.00000000000000000000000000004632 116.0
PYH3_k127_7479341_0 Esterase of the alpha-beta hydrolase superfamily - - - 3.85e-232 747.0
PYH3_k127_7497404_0 transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 539.0
PYH3_k127_7497404_1 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004174 278.0
PYH3_k127_7497404_2 ABC transporter K01990 - - 0.000000000926 60.0
PYH3_k127_7497404_3 Domain of unknown function (DUF4340) - - - 0.0001828 53.0
PYH3_k127_7538442_0 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 3.575e-223 710.0
PYH3_k127_7567299_0 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006282 412.0
PYH3_k127_7567299_1 SurA N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 300.0
PYH3_k127_7567299_2 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000001154 218.0
PYH3_k127_7567299_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000001964 196.0
PYH3_k127_7637381_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 2.728e-240 747.0
PYH3_k127_7637381_1 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000003462 173.0
PYH3_k127_7641197_0 ABC transporter K01999 - - 4.343e-198 624.0
PYH3_k127_7641197_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005869 493.0
PYH3_k127_7641197_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 444.0
PYH3_k127_7641197_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007379 415.0
PYH3_k127_7641197_4 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 393.0
PYH3_k127_7641197_5 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 380.0
PYH3_k127_7641197_6 N-terminal half of MaoC dehydratase K17865 - 4.2.1.55 0.0000000000000000000000000000000000000000000000000006571 188.0
PYH3_k127_7641197_7 Electron transfer flavoprotein alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000003961 187.0
PYH3_k127_7641197_8 AMP-binding enzyme K00666,K02182 - 6.2.1.48 0.00000000000000000000000001349 109.0
PYH3_k127_7692206_0 Putative ATP-binding cassette K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 503.0
PYH3_k127_7721328_0 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 296.0
PYH3_k127_7721328_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
PYH3_k127_7721328_2 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001619 243.0
PYH3_k127_7721328_3 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000000000000000007072 171.0
PYH3_k127_7721328_4 Uncharacterized ACR, COG1993 - - - 0.0000000000000000000000000000002155 132.0
PYH3_k127_7754411_0 HAD-superfamily subfamily IB hydrolase, TIGR01490 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 334.0
PYH3_k127_7754411_1 Psort location CytoplasmicMembrane, score 10.00 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000713 289.0
PYH3_k127_7754411_2 Belongs to the DnaA family K10763 - - 0.0000000000000009201 78.0
PYH3_k127_7758109_0 Tetratricopeptide repeat - - - 2.752e-198 640.0
PYH3_k127_7758109_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000595 225.0
PYH3_k127_7758109_2 - - - - 0.0000000000000000000000004433 115.0
PYH3_k127_7758109_3 transcriptional regulator, SARP family - - - 0.000002324 59.0
PYH3_k127_7758109_4 TIR domain - - - 0.00009022 54.0
PYH3_k127_7767339_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000009884 213.0
PYH3_k127_7767339_1 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.0000000000000000000000000000000000000000000000000000002032 199.0
PYH3_k127_7767339_2 Domain of unknown function (DUF4390) - - - 0.000000000000000000000000000000000000000000000003473 185.0
PYH3_k127_7787420_0 RF-1 domain K15034 - - 0.00000000000000000000000000000000000000000000000009813 180.0
PYH3_k127_7787420_1 Uncharacterised protein family (UPF0149) K07039 - - 0.00000000000000000000000000000001548 143.0
PYH3_k127_78018_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 8.502e-207 649.0
PYH3_k127_78018_1 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 313.0
PYH3_k127_78018_2 CoA-binding protein K06929 - - 0.000000000000000000000000000000000000000000000000000000000000000000007831 246.0
PYH3_k127_7830878_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0 2228.0
PYH3_k127_7830878_1 Fructose-bisphosphate aldolase, class II, Calvin cycle subtype K01624 - 4.1.2.13 6.239e-212 660.0
PYH3_k127_7830878_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 3.042e-211 665.0
PYH3_k127_7830878_3 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 575.0
PYH3_k127_7830878_4 Fe-S cluster K03616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 397.0
PYH3_k127_7830878_5 Iron-binding zinc finger CDGSH type - - - 0.000000000000000000000000000002936 121.0
PYH3_k127_7830878_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000005877 89.0
PYH3_k127_7859_0 Hydrogenase accessory protein HypB K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 488.0
PYH3_k127_7859_1 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000000000000000000000000006142 175.0
PYH3_k127_7859_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.00000000000000000001694 106.0
PYH3_k127_7859_3 Nickel-dependent hydrogenase - - - 0.0000000000003197 72.0
PYH3_k127_7862944_0 homoserine dehydrogenase K00003 - 1.1.1.3 7.614e-229 714.0
PYH3_k127_7862944_1 Aminotransferase K14260 - 2.6.1.2,2.6.1.66 3.103e-221 694.0
PYH3_k127_7862944_10 Signal Transduction Histidine Kinase - - - 0.0000000000009468 82.0
PYH3_k127_7862944_2 Aminotransferase class I and II K14261 - - 2.565e-209 655.0
PYH3_k127_7862944_3 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 473.0
PYH3_k127_7862944_4 Haloacid dehalogenase-like hydrolase K20881 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003325 311.0
PYH3_k127_7862944_5 CoA-binding domain protein K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004886 297.0
PYH3_k127_7862944_6 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000001877 237.0
PYH3_k127_7862944_7 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000000009987 142.0
PYH3_k127_7862944_8 Threonine synthase K01733 - 4.2.3.1 0.000000000000000000000077 98.0
PYH3_k127_7862944_9 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000002378 94.0
PYH3_k127_7874134_0 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008154 406.0
PYH3_k127_7874134_1 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772,K03815 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 349.0
PYH3_k127_7874134_2 4Fe-4S ferredoxin K18930 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005708 331.0
PYH3_k127_7874134_3 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000002998 263.0
PYH3_k127_7874134_4 phosphoribosyltransferase K00760 - 2.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000001169 248.0
PYH3_k127_7874134_5 DsrE/DsrF-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002583 224.0
PYH3_k127_7874134_6 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.00000000000000000000000000000001123 128.0
PYH3_k127_7876789_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 4.606e-247 773.0
PYH3_k127_7876789_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000001505 227.0
PYH3_k127_7878395_0 Hydrogenase maturation protease K03605 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002839 243.0
PYH3_k127_7878395_1 Helix-turn-helix K21498 - - 0.0000000000000000000000000002147 116.0
PYH3_k127_7878395_2 Hydrogenase assembly chaperone hypC hupF K04653 - - 0.0000000000000000000000000005334 115.0
PYH3_k127_7878395_3 Hydrogenase-1 expression protein HyaE K03619 - - 0.000000000000000000000006399 117.0
PYH3_k127_7899397_0 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004494 501.0
PYH3_k127_7899397_1 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005338 344.0
PYH3_k127_7899397_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein K00184 - - 0.0000000000000000000000000000000000000000000000000000000002943 203.0
PYH3_k127_7941018_0 Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 501.0
PYH3_k127_7941018_1 Transketolase, pyrimidine binding domain K00162 - 1.2.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006471 498.0
PYH3_k127_7941018_2 TIR domain - - - 0.000000000000000000000000000000000000000003603 160.0
PYH3_k127_7980575_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009035 329.0
PYH3_k127_7980575_1 MMPL family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000546 267.0
PYH3_k127_7980575_2 transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002568 252.0
PYH3_k127_7988780_0 DNA internalization-related competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003624 269.0
PYH3_k127_7988780_1 PFAM glycosyl transferase family 9 K02841 - - 0.000000000000000000000000000000000000000000000000000000000007424 211.0
PYH3_k127_7988780_2 Phospholipid methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000004858 201.0
PYH3_k127_7988780_3 - - - - 0.00000000000000000000009116 101.0
PYH3_k127_7992440_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001067 533.0
PYH3_k127_7992440_1 Polysaccharide biosynthesis protein - - - 0.00000152 50.0
PYH3_k127_8012410_0 ABC-2 family transporter protein K19341 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001072 427.0
PYH3_k127_8012410_1 AAA domain, putative AbiEii toxin, Type IV TA system K19340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002116 241.0
PYH3_k127_8012410_2 NosL K19342 - - 0.00000000000000000000000000000000000000000000000000000000000003527 231.0
PYH3_k127_8012410_3 - - - - 0.000000000002662 68.0
PYH3_k127_8017870_0 Belongs to the CarB family K01955 - 6.3.5.5 2.645e-292 904.0
PYH3_k127_8017870_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008589 260.0
PYH3_k127_8017870_2 Domain of unknown function (DUF4149) - - - 0.00000000000003419 74.0
PYH3_k127_807073_0 PFAM MgtC SapB transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 494.0
PYH3_k127_807073_1 Single-stranded-DNA-specific exonuclease RecJ K07462 - - 0.0000000000000000000000000000000000000000000000000000000000001939 215.0
PYH3_k127_807073_2 Pfam:DUF1446 - - - 0.00000002357 66.0
PYH3_k127_8134106_0 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004575 421.0
PYH3_k127_8134106_1 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000000000000000000000000000000000000000000002861 216.0
PYH3_k127_8134106_2 Predicted nucleotide-binding protein containing TIR-like domain - - - 0.000000006488 68.0
PYH3_k127_8134106_3 - - - - 0.0000001141 58.0
PYH3_k127_8140732_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 4.634e-261 816.0
PYH3_k127_8140732_1 Exodeoxyribonuclease III K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 393.0
PYH3_k127_8140732_3 Nitrogen metabolism transcriptional regulator, NtrC, Fis Family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000008923 68.0
PYH3_k127_8140732_4 Subtilase family - - - 0.00000002436 63.0
PYH3_k127_8141279_0 ribonuclease, Rne Rng family K08301 - - 6.955e-233 739.0
PYH3_k127_8141279_1 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000575 271.0
PYH3_k127_8141279_2 integral membrane protein K02221 - - 0.00000000000000000000000000000000000000000000000000000000002962 211.0
PYH3_k127_8141279_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000007505 138.0
PYH3_k127_8141279_4 DUF167 K09131 - - 0.00000000000000000000000006413 110.0
PYH3_k127_8157845_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 529.0
PYH3_k127_8157845_1 aldo-keto reductase (NADP) activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001551 357.0
PYH3_k127_8157845_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000009029 219.0
PYH3_k127_8157845_3 PFAM peptidase M48 Ste24p - - - 0.0000000000000000000000000000000000000000000000000000000471 211.0
PYH3_k127_8184349_0 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 526.0
PYH3_k127_8184349_1 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 450.0
PYH3_k127_8184349_2 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009115 314.0
PYH3_k127_8184349_3 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000002033 160.0
PYH3_k127_8184349_4 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.0000000000000000000000000000000000002024 141.0
PYH3_k127_8184349_5 - - - - 0.000002905 53.0
PYH3_k127_8184480_0 ATP-grasp domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000278 328.0
PYH3_k127_8184480_1 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.00000000000000000000000000000000000000000001851 166.0
PYH3_k127_8185962_0 CoA-binding domain protein K09181 - - 1.814e-244 767.0
PYH3_k127_8201695_0 Part of a membrane complex involved in electron transport K03614 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003344 464.0
PYH3_k127_8201695_1 Part of a membrane complex involved in electron transport K03615 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000991 443.0
PYH3_k127_8201695_2 FMN_bind K03612 - - 0.0000000000000000000000000000000000000000000000000000000000000000005272 249.0
PYH3_k127_8201695_3 Part of a membrane complex involved in electron transport K03613 - - 0.0000000000000000000000000000000000000000000000000000000000000000009541 243.0
PYH3_k127_821733_0 Radical SAM K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 597.0
PYH3_k127_821733_1 long-chain fatty acid transport protein K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 473.0
PYH3_k127_821733_2 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000000000000002265 231.0
PYH3_k127_821733_3 FecR protein - - - 0.000000000000000000000000000001329 133.0
PYH3_k127_821733_4 Protein of unknown function (DUF560) - - - 0.00000000000001125 87.0
PYH3_k127_821733_5 geranylgeranyl reductase - - - 0.00000000000141 68.0
PYH3_k127_823057_0 Molecular chaperone. Has ATPase activity K04079 - - 1.542e-293 914.0
PYH3_k127_823057_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003215 357.0
PYH3_k127_823057_2 PFAM MaoC domain protein dehydratase K14449 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009436,GO:0009987,GO:0015977,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0019752,GO:0032787,GO:0043427,GO:0043436,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0046395,GO:0046487,GO:0071704,GO:0072329,GO:1901575 4.2.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 305.0
PYH3_k127_823057_3 Belongs to the enoyl-CoA hydratase isomerase family K13816 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001028 265.0
PYH3_k127_823057_4 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000136 246.0
PYH3_k127_823057_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000921 212.0
PYH3_k127_823057_6 Ribonuclease T2 family - - - 0.00000000000000000000000000000000000000000001353 179.0
PYH3_k127_8267899_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001256 591.0
PYH3_k127_8267899_1 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002908 255.0
PYH3_k127_8267899_2 molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000006684 196.0
PYH3_k127_8294439_0 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001338 444.0
PYH3_k127_8294439_1 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002763 273.0
PYH3_k127_8294629_0 4Fe-4S dicluster domain - - - 2.296e-231 745.0
PYH3_k127_8294629_1 Protein of unknown function (DUF3305) - - - 0.00000000000000000000000000000000000000298 152.0
PYH3_k127_8294629_2 Protein of unknown function (DUF3306) - - - 0.00000000000000000000001422 113.0
PYH3_k127_833273_0 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 347.0
PYH3_k127_833273_1 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000008641 256.0
PYH3_k127_833273_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000834 130.0
PYH3_k127_833273_3 Glycine zipper 2TM domain - - - 0.0000000000000000000608 91.0
PYH3_k127_8336983_0 Aminoacyl-tRNA editing domain K03976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008554 242.0
PYH3_k127_8336983_1 PFAM transcription elongation factor GreA GreB - - - 0.00000000000000000000000000000000000000000000007137 178.0
PYH3_k127_8336983_2 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000008242 116.0
PYH3_k127_8336983_3 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.000000002142 59.0
PYH3_k127_8390079_0 Polysaccharide biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 525.0
PYH3_k127_8390079_1 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 494.0
PYH3_k127_8390079_2 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 359.0
PYH3_k127_8390079_3 Glycosyl transferases group 1 K03208 - - 0.0000000000000000000000000000000000002476 143.0
PYH3_k127_8390079_4 PIN domain K07065 - - 0.0000000000000000000000000000000001078 137.0
PYH3_k127_8407358_0 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.099e-293 912.0
PYH3_k127_8407358_1 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 1.862e-200 627.0
PYH3_k127_8407358_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 516.0
PYH3_k127_8407358_3 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000857 322.0
PYH3_k127_8407358_4 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000218 219.0
PYH3_k127_8407358_5 shape-determining protein MreD K03571 - - 0.000000000000000000000000000000000000000003127 164.0
PYH3_k127_8407358_6 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000008188 135.0
PYH3_k127_8420504_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 1.102e-278 884.0
PYH3_k127_8420504_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 433.0
PYH3_k127_8420504_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003317 361.0
PYH3_k127_8420504_3 Protein of unknown function (DUF2782) - - - 0.0000000000000000000000000001875 118.0
PYH3_k127_8420504_4 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000003116 111.0
PYH3_k127_8430802_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 3.049e-251 781.0
PYH3_k127_8430802_1 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 4.094e-218 685.0
PYH3_k127_8430802_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000003844 265.0
PYH3_k127_8430802_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000000006927 192.0
PYH3_k127_8430802_4 - - - - 0.0000000000000000000000000000000000000000000000009068 184.0
PYH3_k127_8430802_5 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000002016 177.0
PYH3_k127_8430802_6 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.1.2.10 0.000000000000000000000000008467 110.0
PYH3_k127_8431202_0 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 433.0
PYH3_k127_8431202_1 NmrA-like family K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001663 362.0
PYH3_k127_8431202_2 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000003 251.0
PYH3_k127_8444246_0 PFAM Peptidase M16 K07263 - - 1.044e-210 662.0
PYH3_k127_8444246_1 Peptidase M16 inactive domain K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007855 535.0
PYH3_k127_8444246_2 methyltransferase K08316 - 2.1.1.171 0.00000000000000000000000000000000000009694 143.0
PYH3_k127_8449065_0 Phosphatidate cytidylyltransferase K00981 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0009273,GO:0009987,GO:0016020,GO:0042546,GO:0044085,GO:0044464,GO:0071554,GO:0071840,GO:0071944 2.7.7.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005744 424.0
PYH3_k127_8449065_1 Acyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001845 270.0
PYH3_k127_8453745_0 overlaps another CDS with the same product name K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 538.0
PYH3_k127_8453745_1 CP COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K05577 - 1.6.5.3 0.000000000003587 68.0
PYH3_k127_8468494_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 591.0
PYH3_k127_8471288_0 O-acetylhomoserine K01740 - 2.5.1.49 1.159e-230 719.0
PYH3_k127_8471288_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008796 338.0
PYH3_k127_8471288_2 Surface antigen K07278 - - 0.000000000000000000000000002712 119.0
PYH3_k127_8472352_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 2.562e-210 664.0
PYH3_k127_8472352_1 PFAM UBA THIF-type NAD FAD binding protein K21029 - 2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005621 374.0
PYH3_k127_8472352_2 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 339.0
PYH3_k127_8475265_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1089.0
PYH3_k127_8475265_1 Aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 559.0
PYH3_k127_8475265_2 PFAM Protein-tyrosine phosphatase, low molecular weight K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000001233 199.0
PYH3_k127_8475265_3 Belongs to the GcvT family K06980 - - 0.00000000000000000000000000000000000000003132 162.0
PYH3_k127_8476009_0 Tetratricopeptide repeat K02200 - - 0.000000000000000000000000000000000000006402 148.0
PYH3_k127_8476009_1 PFAM Cytochrome c assembly protein - - - 0.0000000000000000003326 100.0
PYH3_k127_8491014_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 598.0
PYH3_k127_8491014_1 ArgJ family K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000336 136.0
PYH3_k127_8499752_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1120.0
PYH3_k127_8499752_1 PFAM aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 610.0
PYH3_k127_8499752_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003455 561.0
PYH3_k127_8499752_3 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 365.0
PYH3_k127_8504508_0 DNA topoisomerase, type IA, central K03169 - 5.99.1.2 0.0 1150.0
PYH3_k127_8504508_1 DnaJ C terminal domain K05516 - - 0.0000000000000000000000000000000000000000000000000000000000002256 217.0
PYH3_k127_8504508_2 DNA recombination-mediator protein A K04096 - - 0.00000000000005343 72.0
PYH3_k127_8519092_0 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001301 542.0
PYH3_k127_8519092_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 300.0
PYH3_k127_8524983_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 2.103e-274 848.0
PYH3_k127_8524983_1 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 602.0
PYH3_k127_8524983_2 Cytochrome c oxidase, subunit K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 387.0
PYH3_k127_8524983_3 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000495 337.0
PYH3_k127_8524983_4 Putative metal-binding domain of cation transport ATPase K01533 - 3.6.3.4 0.0000000000000000000000000000000000003242 143.0
PYH3_k127_8524983_5 FixH K09926 - - 0.000000000000000000000002141 113.0
PYH3_k127_8524983_6 cytochrome oxidase maturation protein cbb3-type - - - 0.0000000000000001559 79.0
PYH3_k127_8524983_7 Cbb3-type cytochrome oxidase K00407 - - 0.00000000001071 69.0
PYH3_k127_852760_0 PFAM ABC transporter related K01990,K09695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 351.0
PYH3_k127_852760_1 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 358.0
PYH3_k127_8528617_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 2459.0
PYH3_k127_8528617_1 PFAM Ankyrin K10799 - 2.4.2.30 0.00000000004488 68.0
PYH3_k127_8535036_0 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004887 260.0
PYH3_k127_8535036_1 SCO1/SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000172 221.0
PYH3_k127_8535036_2 Cytochrome C and Quinol oxidase polypeptide I - - - 0.0000000000000000000000000000000004722 136.0
PYH3_k127_8552367_0 Belongs to the peptidase S8 family - - - 7.676e-208 655.0
PYH3_k127_8552367_1 Protein of unknown function (DUF447) K09154 - - 0.00000000000000000000000000000000000000000000000000000000000000000006754 238.0
PYH3_k127_8552367_2 Flavoprotein - - - 0.00000000000000000000000000000000000000000000000000000000002011 209.0
PYH3_k127_8562429_0 GIY-YIG type nucleases (URI domain) K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009431 582.0
PYH3_k127_8562429_1 Belongs to the globin family - - - 0.000000000000000000000000008218 117.0
PYH3_k127_8562429_2 Cytochrome c - - - 0.000009161 49.0
PYH3_k127_8595734_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 1.265e-239 746.0
PYH3_k127_8606237_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.461e-301 936.0
PYH3_k127_8606237_1 DNA polymerase III K02342 - 2.7.7.7 1.222e-238 757.0
PYH3_k127_8606237_10 Domain of unknown function (DUF4212) - - - 0.000000000000000000000000000000001848 131.0
PYH3_k127_8606237_11 - - - - 0.00000000000000002335 88.0
PYH3_k127_8606237_12 Recombinase zinc beta ribbon domain K06400 - - 0.000000002296 62.0
PYH3_k127_8606237_13 Radical SAM superfamily - - - 0.0000001316 53.0
PYH3_k127_8606237_2 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 1.003e-214 672.0
PYH3_k127_8606237_3 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 5.21e-205 686.0
PYH3_k127_8606237_4 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 474.0
PYH3_k127_8606237_5 His Kinase A (phospho-acceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003616 440.0
PYH3_k127_8606237_6 PFAM Ion transport K08714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000777 315.0
PYH3_k127_8606237_7 Response regulator receiver domain - - - 0.000000000000000000000000000000000000000000000008179 175.0
PYH3_k127_8606237_8 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000000000000000000000000000002298 175.0
PYH3_k127_8606237_9 transcriptional regulator, XRE family - - - 0.0000000000000000000000000000000000000007192 150.0
PYH3_k127_8622257_0 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 362.0
PYH3_k127_8622257_1 - - - - 0.00000000000000000000000000000000000000008518 162.0
PYH3_k127_8622257_2 glycosyl transferase family - - - 0.0000000000001705 71.0
PYH3_k127_8622425_0 PFAM glycosyl transferase, family 51 K05366 - 2.4.1.129,3.4.16.4 0.0 1069.0
PYH3_k127_8622425_1 mRNA catabolic process - - - 0.000000000000000000000000000000000000000000001376 190.0
PYH3_k127_8644791_0 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009545 265.0
PYH3_k127_8644791_1 OsmC-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000003369 216.0
PYH3_k127_8644791_2 Glycine zipper 2TM domain - - - 0.0000551 49.0
PYH3_k127_8657354_0 UDP-glucoronosyl and UDP-glucosyl transferase - - - 0.00000000000000000000004162 110.0
PYH3_k127_8657354_1 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.0000124 58.0
PYH3_k127_8683529_0 Transmembrane secretion effector - - - 2.522e-234 743.0
PYH3_k127_8683529_1 AsmA family K07289,K07290 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006136 317.0
PYH3_k127_8689484_0 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 9.192e-312 970.0
PYH3_k127_8689484_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 8.571e-196 621.0
PYH3_k127_8689484_2 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 453.0
PYH3_k127_8689484_3 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001862 422.0
PYH3_k127_8689484_4 PFAM AFG1-family ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007582 402.0
PYH3_k127_8689484_5 blue (type 1) copper - - - 0.000000000000000004474 85.0
PYH3_k127_8707837_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1026.0
PYH3_k127_8707837_1 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 0.000000002705 58.0
PYH3_k127_8708799_0 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006561 562.0
PYH3_k127_8708799_1 CNP1-like family - - - 0.000000000000000000000000000000000000000003018 161.0
PYH3_k127_8708799_2 Protein of unknown function (DUF3617) - - - 0.0000000000000001184 92.0
PYH3_k127_8710014_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 2.436e-251 781.0
PYH3_k127_8710014_1 ATPsynthase alpha/beta subunit N-term extension K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001782 269.0
PYH3_k127_8710014_2 ATP synthase subunit D K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002756 275.0
PYH3_k127_8710014_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.0000005916 60.0
PYH3_k127_8718216_0 Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate K00381,K00392 - 1.8.1.2,1.8.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000322 364.0
PYH3_k127_8718216_1 Reduction of activated sulfate into sulfite K00390 - 1.8.4.10,1.8.4.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003235 316.0
PYH3_k127_8760955_0 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004909 462.0
PYH3_k127_8760955_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004239 359.0
PYH3_k127_8763683_0 Thiamine pyrophosphate enzyme, central domain K01608 - 4.1.1.47 2.385e-268 837.0
PYH3_k127_8763683_1 to the hyi family K01816 - 5.3.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 379.0
PYH3_k127_8784816_0 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 302.0
PYH3_k127_8863147_0 AsmA family K07289 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001454 353.0
PYH3_k127_8863147_1 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000001304 222.0
PYH3_k127_8871836_0 Domain of unknown function (DUF3473) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001995 278.0
PYH3_k127_8871836_1 3-demethylubiquinone-9 3-O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000008633 215.0
PYH3_k127_8871836_2 HPP family K07168 - - 0.000000001871 59.0
PYH3_k127_889931_0 Aminotransferase K01845 - 5.4.3.8 7.588e-214 670.0
PYH3_k127_889931_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001016 543.0
PYH3_k127_889931_2 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003914 274.0
PYH3_k127_889931_3 PFAM Cytochrome c, class I - - - 0.0000000000000000000000000000000000000000000000000000000000000000001681 235.0
PYH3_k127_8938306_0 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000198 582.0
PYH3_k127_8938306_1 PFAM type II secretion system protein E K02670 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000793 467.0
PYH3_k127_8938306_2 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001336 448.0
PYH3_k127_8938306_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006472 444.0
PYH3_k127_8938306_4 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 306.0
PYH3_k127_8938306_5 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000000000000005469 230.0
PYH3_k127_8938306_6 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008652,GO:0009014,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016811,GO:0019752,GO:0032153,GO:0042802,GO:0043167,GO:0043169,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0046872,GO:0046914,GO:0050897,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.1.18 0.000000000000000218 89.0
PYH3_k127_8958201_0 chemotaxis K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005254 531.0
PYH3_k127_8958201_1 Histidine kinase K02487,K06596 - - 0.000000000000000000002479 98.0
PYH3_k127_8966201_0 GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000009659 159.0
PYH3_k127_8966201_2 chelatase subunit ChlI K07391 - - 0.00001929 46.0
PYH3_k127_8984214_0 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000000000000000002196 236.0
PYH3_k127_8984214_1 PGAP1-like protein - - - 0.00000000000000000000000000000000001011 140.0
PYH3_k127_8984214_2 Histidine phosphatase superfamily (branch 1) - - - 0.00000000000000000000000000000001254 129.0
PYH3_k127_9006042_0 PQQ-like domain K00114 - 1.1.2.8 1.434e-318 985.0
PYH3_k127_9006042_1 TonB-dependent Receptor Plug K02014 - - 3.011e-251 798.0
PYH3_k127_9006042_10 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000003776 213.0
PYH3_k127_9006042_11 Transposase IS200 like - - - 0.0000000000000000000000000000000000000000000000003388 181.0
PYH3_k127_9006042_12 - - - - 0.00000000000000001518 97.0
PYH3_k127_9006042_13 - - - - 0.0000000000000002644 89.0
PYH3_k127_9006042_2 COG0491 Zn-dependent hydrolases, including glyoxylases K01138 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 374.0
PYH3_k127_9006042_3 histidine kinase HAMP region domain protein K07675 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005668 328.0
PYH3_k127_9006042_4 Sulphur oxidation protein SoxZ K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000317 298.0
PYH3_k127_9006042_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K05796 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004842 284.0
PYH3_k127_9006042_6 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003327 269.0
PYH3_k127_9006042_7 PFAM sigma-54 factor interaction domain-containing protein K21405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002685 247.0
PYH3_k127_9006042_8 helix_turn_helix, Lux Regulon K07689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005841 266.0
PYH3_k127_9006042_9 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000004452 247.0
PYH3_k127_9078608_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000961 523.0
PYH3_k127_9078608_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.00000000000000000000000000000000000000000000000000000000006003 215.0
PYH3_k127_9078608_2 FtsK SpoIIIE K03466 - - 0.0000000000000000000000000000000000000000000000000000000002987 207.0
PYH3_k127_9078608_3 Small MutS-related domain - - - 0.0000000000000000000000000000000000000000000000000002637 191.0
PYH3_k127_9078608_4 Belongs to the P(II) protein family K04751 - - 0.000000000000000000000000001764 111.0
PYH3_k127_9082174_0 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 4.682e-212 662.0
PYH3_k127_9082174_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 406.0
PYH3_k127_9082174_2 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004474 301.0
PYH3_k127_9082174_3 poly(R)-hydroxyalkanoic acid synthase K03821 - - 0.000000000000000000000000000000000000000001609 162.0
PYH3_k127_9082174_4 transcriptional - - - 0.0000000000000000000000000000000000000000187 157.0
PYH3_k127_9106165_0 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 434.0
PYH3_k127_9106165_1 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 350.0
PYH3_k127_9106165_2 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.00000000000000000000000000006163 117.0
PYH3_k127_9106165_3 - - - - 0.00000000000000000000003926 101.0
PYH3_k127_9154200_0 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 433.0
PYH3_k127_9154200_1 glycosyl transferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009691 239.0
PYH3_k127_9154200_2 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000002141 208.0
PYH3_k127_918087_0 Multicopper oxidase K22349 - 1.16.3.3 0.0 2571.0
PYH3_k127_9195071_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 7.105e-251 782.0
PYH3_k127_9195071_1 Belongs to the GARS family K01945 - 6.3.4.13 1.86e-204 644.0
PYH3_k127_9195071_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002692 543.0
PYH3_k127_9195071_3 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.0000000000000000000000000000000001559 134.0
PYH3_k127_9195071_4 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000000001586 117.0
PYH3_k127_9246060_0 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.000000000000000000000000000000000000000000000000000000000000001198 227.0
PYH3_k127_9246060_1 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.00000000000000000000000000000000000000000000000001733 187.0
PYH3_k127_9246060_2 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.000000000000000000000000000000003507 132.0
PYH3_k127_9248616_0 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 359.0
PYH3_k127_9248616_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007031 289.0
PYH3_k127_9248616_2 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000004024 69.0
PYH3_k127_9283052_0 Transporter associated domain K06189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 429.0
PYH3_k127_9283052_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000006662 180.0
PYH3_k127_9283052_2 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000008736 104.0
PYH3_k127_9294294_0 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 446.0
PYH3_k127_9294294_1 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 366.0
PYH3_k127_9294294_2 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001573 271.0
PYH3_k127_9294294_3 Helix-turn-helix XRE-family like proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000007148 243.0
PYH3_k127_9294294_4 - - - - 0.000000000000000000000000000000000000000000000003008 182.0
PYH3_k127_9294294_5 regulation of methylation-dependent chromatin silencing K03684,K09968 - 3.1.13.5 0.00000000000000000000000000000000000000005082 155.0
PYH3_k127_9294294_7 Domain of unknown function (DUF1330) - - - 0.000000000000000000000327 99.0
PYH3_k127_9294294_8 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000008739 86.0
PYH3_k127_9295406_0 MMPL family - - - 0.0 1161.0
PYH3_k127_9295406_1 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family K10680 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009117 495.0
PYH3_k127_9295406_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003641 332.0
PYH3_k127_9295406_3 Substrate binding domain of ABC-type glycine betaine transport system K02002 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003083 262.0
PYH3_k127_9295406_4 SNARE associated Golgi protein - - - 0.0001659 47.0
PYH3_k127_9325354_0 Participates in both transcription termination and antitermination K02600 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 417.0
PYH3_k127_9325354_1 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000000000004171 188.0
PYH3_k127_9325354_2 Translation, ribosomal structure and biogenesis K01886 - 6.1.1.18 0.00001405 51.0
PYH3_k127_9353433_0 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 1.972e-196 620.0
PYH3_k127_9353433_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 440.0
PYH3_k127_9353433_10 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.000000000000004123 78.0
PYH3_k127_9353433_2 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001616 422.0
PYH3_k127_9353433_3 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
PYH3_k127_9353433_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 365.0
PYH3_k127_9353433_5 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006842 352.0
PYH3_k127_9353433_6 MlaC protein K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000002668 246.0
PYH3_k127_9353433_7 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000003503 222.0
PYH3_k127_9353433_8 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000002145 126.0
PYH3_k127_9353433_9 response to antibiotic K07122 - - 0.0000000000000005701 89.0
PYH3_k127_9359655_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.175e-292 910.0
PYH3_k127_9359655_1 GTP cyclohydrolase K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 314.0
PYH3_k127_9359655_2 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000559 152.0
PYH3_k127_9359655_3 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00003453 46.0
PYH3_k127_9370371_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 519.0
PYH3_k127_9370371_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001417 389.0
PYH3_k127_9370371_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000004611 274.0
PYH3_k127_9370371_3 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.00000000000000000000000000000000000000000000000001539 184.0
PYH3_k127_9384396_0 Heat shock 70 kDa protein K04043 - - 2.036e-321 993.0
PYH3_k127_9384396_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006524 606.0
PYH3_k127_9384396_2 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000001121 178.0
PYH3_k127_9384396_3 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000002409 63.0
PYH3_k127_9389947_0 Family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001404 329.0
PYH3_k127_9389947_1 heptosyltransferase K02849 GO:0000271,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005976,GO:0006629,GO:0008150,GO:0008152,GO:0008610,GO:0008653,GO:0008713,GO:0008920,GO:0009058,GO:0009059,GO:0009103,GO:0009244,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016740,GO:0016757,GO:0033692,GO:0034637,GO:0034645,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044264,GO:0044424,GO:0044444,GO:0044464,GO:0046401,GO:0071704,GO:0071967,GO:1901135,GO:1901137,GO:1901576,GO:1903509 - 0.00000000000000000000000000000000000000000000000000001002 199.0
PYH3_k127_9389947_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 GO:0000166,GO:0000271,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005975,GO:0005976,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008460,GO:0009058,GO:0009059,GO:0009225,GO:0009226,GO:0009987,GO:0016051,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019305,GO:0019438,GO:0030312,GO:0033692,GO:0034637,GO:0034641,GO:0034645,GO:0034654,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044271,GO:0044281,GO:0044464,GO:0045226,GO:0046379,GO:0046383,GO:0046483,GO:0048037,GO:0050662,GO:0051287,GO:0055086,GO:0070404,GO:0071704,GO:0071944,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901576 4.2.1.46 0.00003926 48.0
PYH3_k127_9413516_0 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009943 343.0
PYH3_k127_9413516_1 Adenylate cyclase K01768 - 4.6.1.1 0.000000000000000000000000001041 119.0
PYH3_k127_9484216_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1433.0
PYH3_k127_9484216_1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 456.0
PYH3_k127_9484216_2 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.00000000001885 74.0
PYH3_k127_9522756_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005267 511.0
PYH3_k127_9522756_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000123 499.0
PYH3_k127_9522756_2 Bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 369.0
PYH3_k127_9522756_3 Protein conserved in bacteria - - - 0.0000000007375 66.0
PYH3_k127_9537427_0 Diguanylate cyclase K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 501.0
PYH3_k127_9537427_1 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.000000000003325 68.0
PYH3_k127_9546355_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008985 355.0
PYH3_k127_9546355_1 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 327.0
PYH3_k127_9546355_2 Aspartyl protease K06985 - - 0.0000000000000000000000000000000000000000000000000000000000001597 219.0
PYH3_k127_9546355_3 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.0000000000000000611 81.0
PYH3_k127_9572189_0 Transcriptional regulatory protein, C terminal K07665 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 313.0
PYH3_k127_9572189_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 293.0
PYH3_k127_9572189_2 Member of a two-component regulatory system K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009729 291.0
PYH3_k127_9572189_3 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002087 267.0
PYH3_k127_9572189_4 - K09004 - - 0.00000000000000000000000000000000000003154 145.0
PYH3_k127_9572189_5 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0000000000000000000000000000000001025 144.0
PYH3_k127_9572189_6 - K09004 - - 0.00000000008223 66.0
PYH3_k127_9580157_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002924 284.0
PYH3_k127_9580157_1 Gene 25-like lysozyme K06903 - - 0.00000000000000000000000000000008263 143.0
PYH3_k127_9590542_0 Protein of unknown function (DUF3422) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 440.0
PYH3_k127_9590542_1 Belongs to the UPF0502 family K09915 - - 0.00000000000000000000000000008012 118.0
PYH3_k127_9598457_0 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 2.137e-242 755.0
PYH3_k127_9598457_1 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes K03651 - 3.1.4.53 0.000000000000000000000000000000000000000000000000000006998 199.0
PYH3_k127_9598457_2 PFAM CBS domain containing protein - - - 0.0000000000000000000000000000000000000000001392 168.0
PYH3_k127_9598457_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.0000000000000000000000000000000000003609 152.0
PYH3_k127_9598457_4 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000805 83.0
PYH3_k127_9598457_5 KTSC domain - - - 0.000000000000000009446 85.0
PYH3_k127_9598457_6 psiF repeat - - - 0.000000002081 59.0
PYH3_k127_9600338_0 AcrB/AcrD/AcrF family K03296 - - 0.0 1258.0
PYH3_k127_9600338_1 type I secretion outer membrane protein, TolC K12340 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003489 418.0
PYH3_k127_9600338_2 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 318.0
PYH3_k127_9600338_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000004134 152.0
PYH3_k127_9600338_4 Protein of unknown function (DUF559) - - - 0.0000000000000000000000000000000000005675 144.0
PYH3_k127_9611616_0 DNA polymerase III alpha subunit K02337 - 2.7.7.7 0.0 1307.0
PYH3_k127_9616868_0 Formylmethanofuran-tetrahydromethanopterin formyltransferase K00672 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0009987,GO:0015947,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0030270,GO:0043446,GO:0044237,GO:0071704 2.3.1.101 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 447.0
PYH3_k127_9655288_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.999e-213 668.0
PYH3_k127_9655288_1 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH3_k127_9655288_2 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000000000000000000001465 210.0
PYH3_k127_9658216_0 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 357.0
PYH3_k127_9658216_1 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003247 293.0
PYH3_k127_9658216_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000005068 241.0
PYH3_k127_9658216_3 Pyridine nucleotide-disulphide oxidoreductase K05297 - 1.18.1.1 0.00000000000000000000000000000000000000000000000001737 184.0
PYH3_k127_9658216_4 DsrC like protein - - - 0.000000000000000000000000000000000000000009118 156.0
PYH3_k127_966334_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1384.0
PYH3_k127_966334_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 5.219e-297 926.0
PYH3_k127_966334_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.115e-232 728.0
PYH3_k127_966334_3 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006107,GO:0006108,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009060,GO:0009117,GO:0009987,GO:0015980,GO:0016491,GO:0016614,GO:0016615,GO:0016616,GO:0016999,GO:0017144,GO:0019362,GO:0019637,GO:0019674,GO:0019752,GO:0030060,GO:0034641,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044464,GO:0045333,GO:0046483,GO:0046496,GO:0051186,GO:0055086,GO:0055114,GO:0071704,GO:0072350,GO:0072524,GO:1901360,GO:1901564 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007899 549.0
PYH3_k127_966334_4 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 442.0
PYH3_k127_966334_5 GntR family K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003427 267.0
PYH3_k127_966334_6 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.000000000000000000000000000000000000000000004513 166.0
PYH3_k127_966334_7 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00242 - - 0.00000000000000000000000000009741 128.0
PYH3_k127_966334_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000002004 123.0
PYH3_k127_966334_9 Flavinator of succinate dehydrogenase K09159 - - 0.000000000000005172 77.0
PYH3_k127_9678341_0 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004219 544.0
PYH3_k127_9678341_1 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002015 381.0
PYH3_k127_9678341_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001827 383.0
PYH3_k127_9717222_0 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 6.941e-241 756.0
PYH3_k127_9717222_1 Protein of unknown function (DUF1298) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 443.0
PYH3_k127_9717222_2 Belongs to the GMC oxidoreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006144 324.0
PYH3_k127_9717222_3 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000669 261.0
PYH3_k127_9717222_4 Bacterial transcriptional repressor - - - 0.00000006963 55.0
PYH3_k127_9717222_5 - - - - 0.000001937 61.0
PYH3_k127_9732026_0 Ammonium Transporter K03320 - - 3.086e-219 687.0
PYH3_k127_9732026_1 Glutamate-cysteine ligase K01919 - 6.3.2.2 1.278e-216 679.0
PYH3_k127_9732026_2 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 435.0
PYH3_k127_9732026_3 Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) K01433 - 3.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 427.0
PYH3_k127_9732026_4 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000008388 105.0
PYH3_k127_9736100_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 510.0
PYH3_k127_9736100_1 ABC-type transport system involved in lysophospholipase L1 biosynthesis permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009442 458.0
PYH3_k127_9782931_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1638.0
PYH3_k127_9782931_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004118 541.0
PYH3_k127_9782931_2 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000002059 171.0
PYH3_k127_978844_0 Bacterial type II and III secretion system protein K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008679 434.0
PYH3_k127_978844_1 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000004981 221.0