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Overview

ID MAG03220
Name PYH3_bin.25
Sample SMP0075
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order JAUWGG01
Family
Genus
Species
Assembly information
Completeness (%) 93.13
Contamination (%) 1.81
GC content (%) 60.0
N50 (bp) 12,063
Genome size (bp) 1,715,347

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1499

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1102632_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 479.0
PYH3_k127_1102632_1 PFAM Biotin lipoate A B protein ligase family K03800 - 6.3.1.20 0.0000000000000000000000000000000000000000002119 168.0
PYH3_k127_1102632_2 Thioredoxin - - - 0.00000000000000000000005309 104.0
PYH3_k127_1102632_3 Glycosyl hydrolases family 16 K01179 - 3.2.1.4 0.00000000000001807 87.0
PYH3_k127_1102632_4 Acetyltransferase GNAT Family - - - 0.0000000009168 66.0
PYH3_k127_1234835_0 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 539.0
PYH3_k127_1234835_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 377.0
PYH3_k127_1234835_2 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 347.0
PYH3_k127_1234835_3 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 325.0
PYH3_k127_1234835_4 Fibronectin type III domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 326.0
PYH3_k127_1234835_5 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000000000000000000000000000135 202.0
PYH3_k127_1234835_6 Protein of unknown function (DUF357) K09728 - - 0.0000000000000000000000000009582 115.0
PYH3_k127_1234835_7 Parallel beta-helix repeats - - - 0.000000000003213 80.0
PYH3_k127_1234835_8 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.000000004609 59.0
PYH3_k127_1255735_0 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 586.0
PYH3_k127_1255735_1 Fe-S cluster K04488 - - 0.0000000000000000000000000000000000000000000000000001086 195.0
PYH3_k127_1279542_0 HELICc2 K03722,K10844 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 508.0
PYH3_k127_1279542_1 PFAM PQQ enzyme repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 522.0
PYH3_k127_1279542_10 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000001122 168.0
PYH3_k127_1279542_11 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.000000000000000000000000000000000000000003043 162.0
PYH3_k127_1279542_12 SIS domain K08094 - 5.3.1.27 0.00000000000000000000000000000000000000002073 159.0
PYH3_k127_1279542_13 - - - - 0.0000000000000000000000000000000000000001718 154.0
PYH3_k127_1279542_14 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000001498 153.0
PYH3_k127_1279542_15 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000000006143 154.0
PYH3_k127_1279542_16 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000004819 153.0
PYH3_k127_1279542_17 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 0.000000000000000000000000000000000001369 144.0
PYH3_k127_1279542_18 Pfam:DUF552 K09152 - - 0.00000000000000000000000001539 113.0
PYH3_k127_1279542_19 - - - - 0.00000000000000000000000001935 113.0
PYH3_k127_1279542_2 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006669 475.0
PYH3_k127_1279542_20 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.0000000000000005145 88.0
PYH3_k127_1279542_21 nucleic acid-binding protein, contains PIN domain - - - 0.000001064 52.0
PYH3_k127_1279542_22 NUDIX domain - - - 0.000003265 58.0
PYH3_k127_1279542_23 PIN domain - - - 0.0000663 50.0
PYH3_k127_1279542_24 PFAM SpoVT AbrB - - - 0.0007219 46.0
PYH3_k127_1279542_3 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 332.0
PYH3_k127_1279542_4 PFAM Phosphomethylpyrimidine kinase K00941,K21219,K21220 - 2.5.1.3,2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 295.0
PYH3_k127_1279542_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000004881 221.0
PYH3_k127_1279542_6 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000000008504 221.0
PYH3_k127_1279542_7 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000001366 199.0
PYH3_k127_1279542_8 PFAM Forkhead-associated protein - - - 0.000000000000000000000000000000000000000000000000000001532 213.0
PYH3_k127_1279542_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000001717 199.0
PYH3_k127_1315638_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 448.0
PYH3_k127_1315638_1 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 386.0
PYH3_k127_1315638_10 - - - - 0.00000000000000000000000000000000000001519 154.0
PYH3_k127_1315638_11 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000002039 124.0
PYH3_k127_1315638_12 cytochrome c biogenesis protein K06196 - - 0.000000000000116 84.0
PYH3_k127_1315638_13 Thioredoxin-like - - - 0.0000001288 64.0
PYH3_k127_1315638_14 Tetratricopeptide repeat - - - 0.000009482 57.0
PYH3_k127_1315638_15 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0001009 55.0
PYH3_k127_1315638_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 334.0
PYH3_k127_1315638_3 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003232 334.0
PYH3_k127_1315638_4 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003041 265.0
PYH3_k127_1315638_5 TIGRFAM TIGR00268 family protein K06864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002165 263.0
PYH3_k127_1315638_6 Iron permease FTR1 family K07243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003373 259.0
PYH3_k127_1315638_7 Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000581 240.0
PYH3_k127_1315638_8 - - - - 0.00000000000000000000000000000000000000000002933 173.0
PYH3_k127_1315638_9 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000359 167.0
PYH3_k127_1316906_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006121 521.0
PYH3_k127_1316906_1 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000000000002145 134.0
PYH3_k127_1316906_2 PFAM PKD domain containing protein - - - 0.000000000000000000000001508 123.0
PYH3_k127_1316906_3 Fibronectin type III domain - - - 0.0000000000000002538 96.0
PYH3_k127_1316906_4 ig-like, plexins, transcription factors - - - 0.00000000000002698 89.0
PYH3_k127_1316906_5 domain, Protein - - - 0.0000000003609 74.0
PYH3_k127_1316906_6 OmpA family - - - 0.0000000224 68.0
PYH3_k127_1316906_7 - - - - 0.0000001276 67.0
PYH3_k127_1316906_8 40-residue YVTN family beta-propeller repeat - - - 0.00001355 60.0
PYH3_k127_1409895_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005272 506.0
PYH3_k127_1409895_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006441 459.0
PYH3_k127_1409895_10 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000001408 181.0
PYH3_k127_1409895_11 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000001572 167.0
PYH3_k127_1409895_12 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000007272 124.0
PYH3_k127_1409895_13 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000000000000000000004301 106.0
PYH3_k127_1409895_14 PIN domain - - - 0.000000000000000000001021 101.0
PYH3_k127_1409895_15 - - - - 0.00000000000000000007426 97.0
PYH3_k127_1409895_16 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K07342 - - 0.0000000000000167 75.0
PYH3_k127_1409895_17 FR47-like protein - - - 0.000000000001732 76.0
PYH3_k127_1409895_18 Integrin alpha (beta-propellor repeats). - - - 0.000000001922 72.0
PYH3_k127_1409895_19 von Willebrand factor, type A K07114 - - 0.00000001005 69.0
PYH3_k127_1409895_2 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002213 411.0
PYH3_k127_1409895_20 Protein of unknown function DUF131 - - - 0.00000006243 61.0
PYH3_k127_1409895_21 - - - - 0.0000001832 57.0
PYH3_k127_1409895_22 membrane K08981 - - 0.0000007594 58.0
PYH3_k127_1409895_23 SpoVT / AbrB like domain - - - 0.000001063 55.0
PYH3_k127_1409895_24 primary miRNA processing - GO:0000375,GO:0000377,GO:0000398,GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006351,GO:0006355,GO:0006366,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0006950,GO:0006952,GO:0007275,GO:0007399,GO:0008150,GO:0008152,GO:0008283,GO:0008380,GO:0009058,GO:0009059,GO:0009301,GO:0009605,GO:0009607,GO:0009617,GO:0009889,GO:0009892,GO:0009987,GO:0010033,GO:0010467,GO:0010468,GO:0010556,GO:0010605,GO:0010608,GO:0010629,GO:0010720,GO:0014070,GO:0016070,GO:0016071,GO:0016073,GO:0016246,GO:0016441,GO:0016458,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019827,GO:0022008,GO:0030154,GO:0030422,GO:0031047,GO:0031050,GO:0031053,GO:0031323,GO:0031326,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032774,GO:0032991,GO:0033168,GO:0034470,GO:0034641,GO:0034645,GO:0034654,GO:0034660,GO:0035194,GO:0035195,GO:0035196,GO:0036404,GO:0040029,GO:0042221,GO:0042742,GO:0042795,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043331,GO:0043900,GO:0043901,GO:0043903,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0045069,GO:0045071,GO:0045595,GO:0045597,GO:0046483,GO:0046685,GO:0048518,GO:0048519,GO:0048522,GO:0048525,GO:0048699,GO:0048731,GO:0048856,GO:0048869,GO:0050767,GO:0050769,GO:0050789,GO:0050792,GO:0050793,GO:0050794,GO:0050829,GO:0050896,GO:0051094,GO:0051171,GO:0051239,GO:0051240,GO:0051252,GO:0051704,GO:0051707,GO:0051716,GO:0051960,GO:0051962,GO:0060255,GO:0060284,GO:0065007,GO:0070013,GO:0070887,GO:0070918,GO:0071310,GO:0071359,GO:0071407,GO:0071704,GO:0080090,GO:0090304,GO:0097150,GO:0097159,GO:0097659,GO:0098542,GO:0098727,GO:0098781,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1901698,GO:1901699,GO:1903506,GO:1903900,GO:1903901,GO:2000026,GO:2000112,GO:2001141 - 0.0003276 44.0
PYH3_k127_1409895_3 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009716 312.0
PYH3_k127_1409895_4 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 311.0
PYH3_k127_1409895_5 Helix-turn-helix XRE-family like proteins K07728 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004966 267.0
PYH3_k127_1409895_6 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000001581 242.0
PYH3_k127_1409895_7 Pfam:DUF137 K09722 - 6.3.2.36 0.0000000000000000000000000000000000000000000000000000000000000000001405 239.0
PYH3_k127_1409895_8 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000002097 213.0
PYH3_k127_1409895_9 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.00000000000000000000000000000000000000000000000000001229 200.0
PYH3_k127_1417689_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 4.7e-225 711.0
PYH3_k127_1417689_1 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006102 368.0
PYH3_k127_1417689_2 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0009451,GO:0009987,GO:0016070,GO:0016740,GO:0016741,GO:0032259,GO:0034641,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:1901360 2.1.1.166 0.0000000000000000000000000000000000000000000000006657 182.0
PYH3_k127_1417689_3 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000003122 160.0
PYH3_k127_1417689_4 PFAM Glyoxalase bleomycin resistance protein dioxygenase K01759,K05606 - 4.4.1.5,5.1.99.1 0.0000000000000000000000000000001192 127.0
PYH3_k127_1417689_5 - - - - 0.00000000000000001217 84.0
PYH3_k127_1417689_6 PFAM extracellular solute-binding protein, family 5 - - - 0.0000003997 62.0
PYH3_k127_1446931_0 Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin K17488 GO:0003674,GO:0003824,GO:0003933,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044682 3.5.4.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 311.0
PYH3_k127_1446931_1 PFAM Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000006986 205.0
PYH3_k127_1446931_2 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000000000008429 203.0
PYH3_k127_1446931_3 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000005212 162.0
PYH3_k127_1446931_4 Thiol-disulfide oxidoreductase which is required in disulfide reduction during c-type cytochrome synthesis. May accept reducing equivalents from CcdA, leading to breakage of disulfide bonds in apocytochrome c - GO:0008150,GO:0009987,GO:0016043,GO:0017004,GO:0022607,GO:0034622,GO:0043933,GO:0044085,GO:0065003,GO:0071840 - 0.000000000004123 76.0
PYH3_k127_1446931_5 transcriptional regulators - - - 0.000000000005943 71.0
PYH3_k127_1446931_6 Vitamin k epoxide reductase - - - 0.00000000006862 70.0
PYH3_k127_1446931_7 transcriptional regulators - - - 0.00000008886 58.0
PYH3_k127_1540346_0 GMP synthase C terminal domain K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 446.0
PYH3_k127_1540346_1 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 452.0
PYH3_k127_1540346_10 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000003597 133.0
PYH3_k127_1540346_11 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000003392 121.0
PYH3_k127_1540346_12 - - - - 0.0000000000000000000000000002817 119.0
PYH3_k127_1540346_13 Protein of unknown function DUF72 - - - 0.000000000000000001626 94.0
PYH3_k127_1540346_14 archaeal coiled-coil protein - - - 0.000000000000002874 86.0
PYH3_k127_1540346_15 extracellular matrix structural constituent K02035 - - 0.0002521 51.0
PYH3_k127_1540346_2 Sugar (and other) transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 411.0
PYH3_k127_1540346_3 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 GO:0002097,GO:0002101,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016879,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 6.3.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000549 390.0
PYH3_k127_1540346_4 COG1055 Na H antiporter NhaD and related arsenite permeases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000204 297.0
PYH3_k127_1540346_5 Nucleotidyl transferase K00966 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001788 289.0
PYH3_k127_1540346_6 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000007071 234.0
PYH3_k127_1540346_7 Ribosomal RNA adenine dimethylases K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000006262 223.0
PYH3_k127_1540346_8 - - - - 0.000000000000000000000000000000000000000000000000009674 196.0
PYH3_k127_1540346_9 cellular water homeostasis K05802,K16052 - - 0.0000000000000000000000000000000000003677 154.0
PYH3_k127_162089_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 1.476e-279 874.0
PYH3_k127_162089_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005397 609.0
PYH3_k127_162089_10 Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006566 323.0
PYH3_k127_162089_11 ABC-type multidrug transport system, ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 311.0
PYH3_k127_162089_12 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 317.0
PYH3_k127_162089_13 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006966 297.0
PYH3_k127_162089_14 DNA alkylation repair enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001252 278.0
PYH3_k127_162089_15 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000002446 267.0
PYH3_k127_162089_16 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000001131 266.0
PYH3_k127_162089_17 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001744 278.0
PYH3_k127_162089_18 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008066 269.0
PYH3_k127_162089_19 4Fe-4S ferredoxin iron-sulfur binding domain protein K00124 - - 0.000000000000000000000000000000000000000000000000000000000000001324 224.0
PYH3_k127_162089_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000976 534.0
PYH3_k127_162089_20 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.0000000000000000000000000000000000000000000000000000000000000613 218.0
PYH3_k127_162089_21 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000001207 225.0
PYH3_k127_162089_22 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000003628 166.0
PYH3_k127_162089_23 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000000000000000000000001855 173.0
PYH3_k127_162089_24 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000001416 165.0
PYH3_k127_162089_25 GCN5 family acetyltransferase - - - 0.00000000000000000000000000000000000002484 160.0
PYH3_k127_162089_26 Nitrous oxide-stimulated promoter - - - 0.000000000000000000000000000000000296 134.0
PYH3_k127_162089_27 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000004488 138.0
PYH3_k127_162089_28 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000005858 147.0
PYH3_k127_162089_29 - - - - 0.00000000000000003206 83.0
PYH3_k127_162089_3 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000374 491.0
PYH3_k127_162089_30 - - - - 0.00000000000001033 74.0
PYH3_k127_162089_31 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.0000000001254 72.0
PYH3_k127_162089_32 TIGRFAM Outer membrane protein K13735,K20276 - - 0.0000000001441 76.0
PYH3_k127_162089_33 PA14 domain - - - 0.000000006767 70.0
PYH3_k127_162089_35 transcriptional K03718,K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016597,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031406,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043177,GO:0043200,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.000001241 60.0
PYH3_k127_162089_36 Molybdopterin converting factor, small subunit K03636,K21142 - 2.8.1.12 0.00002366 51.0
PYH3_k127_162089_37 - - - - 0.00003556 54.0
PYH3_k127_162089_39 CopG Arc MetJ family K07746 - - 0.0006148 46.0
PYH3_k127_162089_4 Coenzyme A transferase K01039 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002165 401.0
PYH3_k127_162089_5 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006188 411.0
PYH3_k127_162089_6 CoA-transferase family III K18702 - 2.8.3.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 392.0
PYH3_k127_162089_7 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003893 428.0
PYH3_k127_162089_8 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002407 366.0
PYH3_k127_162089_9 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004101 359.0
PYH3_k127_1656644_0 amino acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005851 449.0
PYH3_k127_1656644_1 4Fe-4S single cluster domain K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 348.0
PYH3_k127_1656644_10 - - - - 0.000000000000001327 79.0
PYH3_k127_1656644_11 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.00000000000002224 84.0
PYH3_k127_1656644_12 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.000000000001668 78.0
PYH3_k127_1656644_13 PFAM MscS Mechanosensitive ion channel K16052 - - 0.00000000001765 76.0
PYH3_k127_1656644_2 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000695 288.0
PYH3_k127_1656644_3 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001954 274.0
PYH3_k127_1656644_4 snoRNA binding domain, fibrillarin K14564 GO:0000154,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030515,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000003573 214.0
PYH3_k127_1656644_5 - - - - 0.00000000000000000000000000000000000000000000000000275 190.0
PYH3_k127_1656644_6 Functions by promoting the formation of the first peptide bond K03263 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000003821 181.0
PYH3_k127_1656644_7 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000006781 168.0
PYH3_k127_1656644_8 PFAM Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000005428 156.0
PYH3_k127_1656644_9 SMART PAS domain containing protein - - - 0.0000000000000001084 94.0
PYH3_k127_1746401_0 ABC-type multidrug transport system ATPase component K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000005792 230.0
PYH3_k127_1746401_1 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.000000000000000000008757 97.0
PYH3_k127_1746401_2 ABC-2 type transporter K01992 - - 0.00000000000000001468 96.0
PYH3_k127_1769973_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 4.367e-214 677.0
PYH3_k127_1769973_1 KH domain K07041 - - 1.177e-209 660.0
PYH3_k127_1769973_12 - - - - 0.000000001481 60.0
PYH3_k127_1769973_13 protein Sb1211s002020 source - - - 0.00000009817 57.0
PYH3_k127_1769973_16 - - - - 0.0002801 46.0
PYH3_k127_1769973_2 Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp) K09759,K22503 - 6.1.1.12,6.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004972 508.0
PYH3_k127_1769973_3 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 400.0
PYH3_k127_1769973_4 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K06879,K09457 - 1.7.1.13 0.000000000000000000000000000000000003058 142.0
PYH3_k127_1769973_6 OB-fold nucleic acid binding domain - - - 0.00000000000000000002577 97.0
PYH3_k127_1769973_7 Uncharacterised protein family UPF0066 - - - 0.0000000000000000005079 93.0
PYH3_k127_1769973_8 von Willebrand factor, type A K07114 - - 0.000000000000000001327 103.0
PYH3_k127_1769973_9 Sugar-specific transcriptional regulator TrmB - - - 0.0000000000000002 88.0
PYH3_k127_1789019_0 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 8.36e-228 721.0
PYH3_k127_1789019_1 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004298 460.0
PYH3_k127_1789019_2 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 300.0
PYH3_k127_1789019_3 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000068 245.0
PYH3_k127_1789019_4 beta-lactamase domain protein - - - 0.000000000000000000000000000000000000000000000000000002104 199.0
PYH3_k127_1789019_5 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000004305 139.0
PYH3_k127_1789019_6 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000007812 123.0
PYH3_k127_1789019_7 zinc finger - - - 0.0000000001163 64.0
PYH3_k127_1794891_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002115 258.0
PYH3_k127_1794891_1 Uncharacterised protein family (UPF0175) - - - 0.0000000000000000000000000000000000000000000000000000000002414 209.0
PYH3_k127_1794891_2 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000006037 136.0
PYH3_k127_1794891_3 nucleic acid-binding protein contains PIN domain - - - 0.000000000000000000000000000006043 127.0
PYH3_k127_1794891_4 PFAM DNA polymerase beta domain protein region K07075 - - 0.0000000000000000000001099 101.0
PYH3_k127_1794891_5 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007,K21787 - 2.7.9.2 0.000000000000419 75.0
PYH3_k127_1895613_0 Beta-Casp domain K07577 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 460.0
PYH3_k127_1895613_1 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 461.0
PYH3_k127_1895613_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K00333 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004146 371.0
PYH3_k127_1895613_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000002454 263.0
PYH3_k127_1895613_4 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342,K22168 - 1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000005742 171.0
PYH3_k127_1895613_5 ATP synthesis coupled electron transport K00340,K05576 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:0098797,GO:0098803,GO:1901135,GO:1901360,GO:1901564,GO:1902494,GO:1990204 1.6.5.3 0.00000000000000000000008456 101.0
PYH3_k127_1895613_6 NADH ubiquinone oxidoreductase subunit 3 (Chain a) K00330,K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3,1.6.5.3 0.0000000000000000001997 94.0
PYH3_k127_1895613_7 Belongs to the complex I subunit 6 family K00339,K05578 - 1.6.5.3 0.0000000000000007041 80.0
PYH3_k127_1972585_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 8.53e-211 664.0
PYH3_k127_1972585_1 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002464 379.0
PYH3_k127_1972585_2 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 354.0
PYH3_k127_1972585_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 310.0
PYH3_k127_1972585_4 metallopeptidase activity K06974 - - 0.000000000000000000000000000001458 126.0
PYH3_k127_1972585_5 PFAM metallophosphoesterase K06953 - - 0.000000000000000000000000000001761 127.0
PYH3_k127_2057385_0 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000000000001614 187.0
PYH3_k127_2057385_1 Heavy metal translocating P-type atpase - - - 0.00000000000000000000001508 109.0
PYH3_k127_2057385_2 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.000000000000000005405 100.0
PYH3_k127_2057385_3 cellulase activity - - - 0.00000000000001613 89.0
PYH3_k127_2057385_4 cellulase activity - - - 0.000000000004065 80.0
PYH3_k127_2057385_5 Major Facilitator Superfamily K08222 - - 0.000004017 59.0
PYH3_k127_2057385_6 protein conserved in archaea K09723 - - 0.0004832 51.0
PYH3_k127_2135215_0 Archaeal holliday junction resolvase (hjc) - - - 0.0000000000000000000000000000000000000000000006897 173.0
PYH3_k127_2135215_1 helix_turn_helix ASNC type K03718 - - 0.00000000000000000000000000000000000000000001475 168.0
PYH3_k127_2135215_2 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000003641 158.0
PYH3_k127_2135215_3 - - - - 0.0000000098 58.0
PYH3_k127_2244421_0 Phosphoadenosine phosphosulfate reductase family K00390 - 1.8.4.10,1.8.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 565.0
PYH3_k127_2244421_1 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 392.0
PYH3_k127_2244421_10 exo-alpha-(2->6)-sialidase activity - - - 0.00000003835 66.0
PYH3_k127_2244421_2 Dimethylates a single guanine residue at position 26 of a number of tRNAs using S-adenosyl-L-methionine as donor of the methyl groups K00555 GO:0001510,GO:0002940,GO:0003674,GO:0003824,GO:0004809,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.215,2.1.1.216 0.0000000000000000000000000000000000000000000000000000000000000000000001018 260.0
PYH3_k127_2244421_3 Has nucleotide phosphatase activity towards ATP, GTP, CTP, TTP and UTP. May hydrolyze nucleoside diphosphates with lower efficiency K06928 - 3.6.1.15 0.0000000000000000000000000000000000000000000000000000000000000000001331 234.0
PYH3_k127_2244421_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000000000001843 177.0
PYH3_k127_2244421_5 Involved in allosteric regulation of aspartate carbamoyltransferase K00610 - - 0.00000000000000000000000000000000000000000003792 178.0
PYH3_k127_2244421_6 von Willebrand factor, type A K07114 - - 0.0000000000000000000000000000000000007113 162.0
PYH3_k127_2244421_7 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000001168 112.0
PYH3_k127_2244421_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000001272 101.0
PYH3_k127_2244421_9 protein contain chitin-binding domain type 3 - - - 0.000000000000009719 87.0
PYH3_k127_2249478_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.0 1088.0
PYH3_k127_2258679_0 Heat shock 70 kDa protein K04043 - - 1.101e-241 762.0
PYH3_k127_2258679_1 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 406.0
PYH3_k127_2258679_10 phosphoprotein phosphatase activity K07313 - 3.1.3.16 0.00000000000000000000000000000000000000003285 164.0
PYH3_k127_2258679_11 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.0000000000000000000000000000000009656 134.0
PYH3_k127_2258679_12 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000004105 137.0
PYH3_k127_2258679_13 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000002243 126.0
PYH3_k127_2258679_14 - - - - 0.000000000000000000000000000003404 131.0
PYH3_k127_2258679_15 Belongs to the peptidase S16 family K06870 GO:0003674,GO:0003824,GO:0004176,GO:0006508,GO:0006515,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0000001936 63.0
PYH3_k127_2258679_16 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000004916 57.0
PYH3_k127_2258679_17 - - - - 0.00001464 57.0
PYH3_k127_2258679_2 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 382.0
PYH3_k127_2258679_3 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008755 352.0
PYH3_k127_2258679_4 Fic/DOC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002027 258.0
PYH3_k127_2258679_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000003122 245.0
PYH3_k127_2258679_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000007354 239.0
PYH3_k127_2258679_7 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000002543 224.0
PYH3_k127_2258679_8 Beta-lactamase superfamily domain K06136 - - 0.000000000000000000000000000000000000000000000000000005638 203.0
PYH3_k127_2258679_9 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000000000000005504 187.0
PYH3_k127_2366678_0 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000137 296.0
PYH3_k127_2366678_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03047 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000005888 239.0
PYH3_k127_2366678_10 toxin activity - - - 0.000004704 52.0
PYH3_k127_2366678_11 extracellular matrix structural constituent K02035 - - 0.0009053 54.0
PYH3_k127_2366678_2 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.000000000000000000000000000000000000000000000000000000000004505 216.0
PYH3_k127_2366678_3 Located on the platform of the 30S subunit K02948 - - 0.000000000000000000000000000000000000000000000000000000006521 200.0
PYH3_k127_2366678_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.00000000000000000000000000000000000000000000000000000118 198.0
PYH3_k127_2366678_5 Proprotein convertase P-domain - - - 0.0000000000000000000000000000000000000000000000000000029 221.0
PYH3_k127_2366678_6 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000852 144.0
PYH3_k127_2366678_7 Papain family cysteine protease - - - 0.00000000000000000000000106 121.0
PYH3_k127_2366678_8 UbiA prenyltransferase family K17105 - 2.5.1.42 0.000000000000000008646 87.0
PYH3_k127_2366678_9 - - - - 0.00000002263 57.0
PYH3_k127_2484604_0 AAA domain - - - 0.0000000000000000000000000000000000000001924 158.0
PYH3_k127_2484604_1 Belongs to the UPF0107 family K09128 - - 0.000000000000000000000000000000000000005975 157.0
PYH3_k127_2484604_2 RNA binding K07581 - - 0.00000000000000000000003532 109.0
PYH3_k127_2484604_3 - - - - 0.0000003067 65.0
PYH3_k127_256773_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 334.0
PYH3_k127_256773_1 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 340.0
PYH3_k127_256773_10 Integral membrane protein DUF106 - - - 0.00000009866 63.0
PYH3_k127_256773_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 290.0
PYH3_k127_256773_3 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006039 270.0
PYH3_k127_256773_4 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000001021 179.0
PYH3_k127_256773_5 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000001919 152.0
PYH3_k127_256773_6 50S ribosomal protein L37Ae K02921 - - 0.00000000000000000002215 93.0
PYH3_k127_256773_7 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 - - 0.0000000000000001359 84.0
PYH3_k127_256773_8 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.0000000001623 62.0
PYH3_k127_256773_9 Transcription factor Pcc1 K09741 - - 0.000000009758 59.0
PYH3_k127_2591459_0 phenylalanyl-tRNA synthetase, beta subunit K01890 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 466.0
PYH3_k127_2591459_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 326.0
PYH3_k127_2591459_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 329.0
PYH3_k127_2591459_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.000000000000000000000000000000000000000000000000000000000000000000001018 249.0
PYH3_k127_2591459_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.00000000000000000000005898 101.0
PYH3_k127_2591459_5 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.0000000000000000002729 95.0
PYH3_k127_2591459_6 ATP synthase subunit C K02124 - - 0.000000001351 61.0
PYH3_k127_2591459_7 TIGRFAM ATP synthase K02107 - - 0.0002532 48.0
PYH3_k127_2596053_0 metal-binding domain in RNase L inhibitor, RLI K06174 GO:0000166,GO:0003674,GO:0005488,GO:0005506,GO:0005524,GO:0006412,GO:0006413,GO:0006415,GO:0006518,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0017076,GO:0019538,GO:0022411,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032984,GO:0034641,GO:0034645,GO:0035639,GO:0036094,GO:0043021,GO:0043024,GO:0043043,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0043603,GO:0043604,GO:0043624,GO:0043933,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044877,GO:0046872,GO:0046914,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 7.385e-235 741.0
PYH3_k127_2596053_1 Aldehyde ferredoxin oxidoreductase, N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001982 609.0
PYH3_k127_2596053_10 signal transduction protein with CBS domains - - - 0.00000000000000000000000000000003014 134.0
PYH3_k127_2596053_11 4Fe-4S binding domain - - - 0.0000000000000000000000001457 111.0
PYH3_k127_2596053_12 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000000000000000008777 108.0
PYH3_k127_2596053_13 Contacts the emerging nascent chain on the ribosome K03626 - - 0.00000000000000000000001212 104.0
PYH3_k127_2596053_14 Belongs to the UPF0248 family K09715 - - 0.00000000000000003059 83.0
PYH3_k127_2596053_15 Roadblock LC7 family protein K07131 - - 0.000000001595 63.0
PYH3_k127_2596053_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009261 332.0
PYH3_k127_2596053_3 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465,K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.2,3.5.2.3,3.5.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002701 322.0
PYH3_k127_2596053_4 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000005023 244.0
PYH3_k127_2596053_5 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000001556 239.0
PYH3_k127_2596053_6 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000005233 243.0
PYH3_k127_2596053_7 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000000000000000000000000000000000001592 234.0
PYH3_k127_2596053_8 Protein of unknown function (DUF1385) - - - 0.0000000000000000000000000000000000000000000000000000000000000000651 234.0
PYH3_k127_2596053_9 protein conserved in archaea K09746 - - 0.00000000000000000000000000000000000000000000000000000001986 214.0
PYH3_k127_2680113_0 phosphoenolpyruvate carboxykinase (GTP) activity K01596,K01610 - 4.1.1.32,4.1.1.49 1.504e-254 805.0
PYH3_k127_2680113_1 Type II/IV secretion system protein K07332 - - 1.739e-221 698.0
PYH3_k127_2680113_10 Double zinc ribbon - - - 0.000000000000000000000000000001984 142.0
PYH3_k127_2680113_11 AAA ATPase domain K12132 - 2.7.11.1 0.000000000000005222 88.0
PYH3_k127_2680113_12 Parallel beta-helix repeats - - - 0.0000004681 65.0
PYH3_k127_2680113_2 Type II/IV secretion system protein K07332 - - 6.549e-207 659.0
PYH3_k127_2680113_3 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 478.0
PYH3_k127_2680113_4 PFAM ABC transporter related K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 349.0
PYH3_k127_2680113_5 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001415 347.0
PYH3_k127_2680113_6 PFAM ABC-2 type transporter K09694 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000403 291.0
PYH3_k127_2680113_7 Type II secretion system K07333 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007727 278.0
PYH3_k127_2680113_8 Type II secretion system K07333 - - 0.000000000000000000000000000000000000000000000000000000000000001825 230.0
PYH3_k127_2680113_9 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000007297 225.0
PYH3_k127_2714407_0 Belongs to the UPF0273 family - - - 0.0000000000000000000000000000001118 133.0
PYH3_k127_2714407_1 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.000000001233 61.0
PYH3_k127_2748420_0 Glycosyl transferase 4-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 361.0
PYH3_k127_2748420_1 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.0000000000000000000000000000000006155 143.0
PYH3_k127_2748420_3 - - - - 0.00000004475 55.0
PYH3_k127_2781877_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 4.896e-198 643.0
PYH3_k127_2781877_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 353.0
PYH3_k127_2781877_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000029 352.0
PYH3_k127_2781877_3 ATP-grasp domain K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002804 338.0
PYH3_k127_2781877_4 phosphoribosylaminoimidazolesuccinocarboxamide synthase activity K01923 - 6.3.2.6 0.000000000000000000000000000000000000000000000000000009991 192.0
PYH3_k127_2781877_5 Belongs to the eukaryotic ribosomal protein eL40 family K02927 - - 0.00000000001245 66.0
PYH3_k127_2784424_0 Elongator protein 3, MiaB family, Radical SAM K06936 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 300.0
PYH3_k127_2784424_1 - - - - 0.000000000006371 69.0
PYH3_k127_2832051_0 Periplasmic or secreted lipoprotein - - - 0.000008435 60.0
PYH3_k127_2880559_0 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 7.579e-198 631.0
PYH3_k127_2880559_1 Sodium hydrogen exchanger K03455 - - 0.00000000000000000000000000000000000000000008999 180.0
PYH3_k127_2896839_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1568.0
PYH3_k127_2896839_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1239.0
PYH3_k127_2896839_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 372.0
PYH3_k127_2896839_3 Participates in transcription termination K02600 - - 0.0000000000000000000000000000000000001542 147.0
PYH3_k127_2896839_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000002986 95.0
PYH3_k127_2896839_5 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000006072 93.0
PYH3_k127_2977489_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 GO:0003674,GO:0003824,GO:0003916,GO:0003918,GO:0005575,GO:0006139,GO:0006259,GO:0006265,GO:0006725,GO:0006807,GO:0006996,GO:0007059,GO:0008094,GO:0008150,GO:0008152,GO:0009295,GO:0009987,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0051276,GO:0061505,GO:0071103,GO:0071704,GO:0071840,GO:0090304,GO:0140097,GO:1901360 5.99.1.3 6.472e-252 791.0
PYH3_k127_2977489_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 509.0
PYH3_k127_2977489_2 cysteinyl-tRNA synthetase K01883 - 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 445.0
PYH3_k127_2977489_3 cystathionine K01739,K01758,K01760 - 2.5.1.48,4.4.1.1,4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 430.0
PYH3_k127_2977489_4 - - - - 0.0000000000000000000000000000000000005194 150.0
PYH3_k127_2977489_5 transcriptional regulators - - - 0.000000000000000002648 96.0
PYH3_k127_2977489_6 MFS_1 like family - - - 0.0000001179 64.0
PYH3_k127_301136_0 PQQ enzyme repeat K05889,K12132 - 1.1.2.6,2.7.11.1 0.000000000000000000000000000000000000000000000000005541 201.0
PYH3_k127_301136_1 WD-40 repeat - - - 0.00000000000000000000000000000000000000000000000008496 194.0
PYH3_k127_301136_2 4Fe-4S binding domain - - - 0.00000000000000000000000000001564 130.0
PYH3_k127_301136_3 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000009402 106.0
PYH3_k127_3016901_0 - - - - 0.00000000000000000000000000000000000000000000000000001027 194.0
PYH3_k127_3016901_1 Fibronectin type III domain - - - 0.00000000000000000000000000000000000000008761 173.0
PYH3_k127_3016901_2 Staphylococcal nuclease homologue - - - 0.000000000000000000000000000000000000004082 151.0
PYH3_k127_3016901_3 3'-5' exonuclease activity K03546,K03547 - - 0.000000000000000000000001265 118.0
PYH3_k127_3016901_4 translation release factor activity K03265 - - 0.000000000000000722 86.0
PYH3_k127_3016901_5 PFAM SMC domain protein K03546 - - 0.0000000000003502 82.0
PYH3_k127_3016901_6 Tfp pilus assembly protein FimV - - - 0.0000003292 64.0
PYH3_k127_3042441_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 542.0
PYH3_k127_3042441_1 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007857 505.0
PYH3_k127_3042441_10 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.00000000001104 68.0
PYH3_k127_3042441_11 Belongs to the peptidase S8 family K13276,K17734 - - 0.0000000002645 74.0
PYH3_k127_3042441_12 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.000005767 60.0
PYH3_k127_3042441_2 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 497.0
PYH3_k127_3042441_3 Beta propeller domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005072 453.0
PYH3_k127_3042441_4 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004399 380.0
PYH3_k127_3042441_5 Purine nucleoside phosphorylase involved in purine salvage K00772 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007176 338.0
PYH3_k127_3042441_6 ATPase, AAA superfamily - - - 0.00000000000000000000000000000000000000000000000000000009063 216.0
PYH3_k127_3042441_7 Involved in the catabolism of quinolinic acid (QA) K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000001409 180.0
PYH3_k127_3042441_8 archaeal coiled-coil protein - - - 0.0000000000000000000000000000000000000000000297 171.0
PYH3_k127_3042441_9 Transcriptional regulator - - - 0.000000000000000000003433 100.0
PYH3_k127_3112973_0 Belongs to the DEAD box helicase family K11927 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008813 450.0
PYH3_k127_3112973_1 sulfur carrier activity K00549,K04085,K04487,K08363 GO:0002097,GO:0002098,GO:0002143,GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006732,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019538,GO:0019637,GO:0019720,GO:0019725,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042592,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048878,GO:0051186,GO:0051188,GO:0051189,GO:0055082,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0090407,GO:0097163,GO:0140104,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.14,2.8.1.7 0.000000000000000000003634 97.0
PYH3_k127_3112973_2 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000003753 88.0
PYH3_k127_3112973_3 4Fe-4S binding domain protein - - - 0.0000009381 53.0
PYH3_k127_3121127_0 Transglutaminase-like superfamily - - - 0.0000000000000000000000000005536 128.0
PYH3_k127_3121127_1 - - - - 0.0000000000000062 84.0
PYH3_k127_3233608_0 NADH:flavin oxidoreductase / NADH oxidase family K00219 - 1.3.1.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 589.0
PYH3_k127_3233608_1 NADPH-dependent FMN reductase - - - 0.00000000000000000000000000000000000000000000000006331 185.0
PYH3_k127_3233608_2 - - - - 0.000000000000001345 84.0
PYH3_k127_3233608_3 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388,K16885,K16886 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000003088 57.0
PYH3_k127_3233608_4 NADPH-dependent FMN reductase - - - 0.00009889 48.0
PYH3_k127_3250216_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 622.0
PYH3_k127_3250216_1 KEOPS complex Cgi121-like subunit K09119 - - 0.000000001721 70.0
PYH3_k127_3250216_2 Subtilase family K13274,K14645 - - 0.0000000172 64.0
PYH3_k127_3264680_0 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004963 417.0
PYH3_k127_3264680_1 Binds the lower part of the 30S subunit head K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003067 290.0
PYH3_k127_3264680_2 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002179 271.0
PYH3_k127_3264680_3 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000008598 243.0
PYH3_k127_3264680_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000007755 166.0
PYH3_k127_3264680_5 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000902 158.0
PYH3_k127_3264680_6 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 - - 0.00000000000000000000000339 116.0
PYH3_k127_3350403_0 ABC-type multidrug transport system, ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 341.0
PYH3_k127_3350403_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000003597 162.0
PYH3_k127_3350403_2 protein conserved in archaea - - - 0.000000001975 69.0
PYH3_k127_3350403_3 ABC transporter K01990 - - 0.0005346 44.0
PYH3_k127_3368335_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 514.0
PYH3_k127_3368335_1 - - - - 0.0000000000000000000000000000007137 128.0
PYH3_k127_3368335_2 Phosphate transport regulator K07220 - - 0.0000000000000000000000000002536 123.0
PYH3_k127_3368335_3 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.00000000000000000002623 94.0
PYH3_k127_3376345_0 MCM OB domain K10726 - - 4.635e-199 644.0
PYH3_k127_3376345_1 NMD3 family K07562 - - 0.000000000000000000000000000000000000001517 155.0
PYH3_k127_3376345_2 Protein of unknown function (DUF424) K09148 - - 0.0000000000000000000007986 102.0
PYH3_k127_3376345_3 - - - - 0.0000000000000006551 82.0
PYH3_k127_3376345_4 SPFH domain-Band 7 family - - - 0.0004026 45.0
PYH3_k127_3418365_0 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 465.0
PYH3_k127_3418365_1 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.000000000000000000000000000000000000000000000001153 179.0
PYH3_k127_3418365_2 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.00000000000000002198 87.0
PYH3_k127_3418365_3 aminopeptidase activity K09612,K19701,K19702 GO:0003674,GO:0003824,GO:0004177,GO:0005575,GO:0005623,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0036211,GO:0042597,GO:0043170,GO:0043412,GO:0043687,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.11.10,3.4.11.24,3.4.11.6 0.0000000002462 72.0
PYH3_k127_3420895_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001233 410.0
PYH3_k127_3420895_1 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 406.0
PYH3_k127_3420895_10 - - - - 0.0000000000000000000000009174 104.0
PYH3_k127_3420895_11 Protein of unknown function (DUF1634) - - - 0.0001185 49.0
PYH3_k127_3420895_2 helicase superfamily c-terminal domain K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007125 361.0
PYH3_k127_3420895_3 SMART Elongator protein 3 MiaB NifB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 333.0
PYH3_k127_3420895_4 PFAM glycosyl transferase group 1 K12995 - 2.4.1.348 0.000000000000000000000000000000000000000000000000001234 197.0
PYH3_k127_3420895_5 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000218 190.0
PYH3_k127_3420895_6 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.00000000000000000000000000000000000000000002358 174.0
PYH3_k127_3420895_7 PFAM SOUL heme-binding protein - - - 0.0000000000000000000000000000006613 128.0
PYH3_k127_3420895_8 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000073 109.0
PYH3_k127_3420895_9 - - - - 0.0000000000000000000000001272 107.0
PYH3_k127_3458797_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.061e-238 749.0
PYH3_k127_3458797_1 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009398 259.0
PYH3_k127_3458797_2 Subtilase family K01342 - 3.4.21.62 0.00000000000000000000000000000000000000000000000000000000000000000007659 243.0
PYH3_k127_353739_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009456 505.0
PYH3_k127_353739_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000002697 138.0
PYH3_k127_353739_2 Antidote-toxin recognition MazE, bacterial antitoxin - - - 0.00000000000005947 74.0
PYH3_k127_353739_3 Citrate transporter - - - 0.000000000001516 68.0
PYH3_k127_353739_4 - - - - 0.0000000001766 65.0
PYH3_k127_353739_5 - - - - 0.00000001436 58.0
PYH3_k127_353739_6 FR47-like protein - - - 0.000001851 59.0
PYH3_k127_353739_7 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0002875 51.0
PYH3_k127_3549459_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K05996,K07752 - 3.4.17.18,3.4.17.22 0.00000000000000000000000000000000000000000000000000000000000000000000001315 272.0
PYH3_k127_3549459_1 Diphthamide synthase K06927 - 6.3.1.14 0.0000000000000000000000000000000000000000000000000000007524 201.0
PYH3_k127_3588572_0 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000000000183 225.0
PYH3_k127_3588572_1 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000289 187.0
PYH3_k127_3588572_2 Pfam:KaiC - - - 0.0000000000000000000000000000000000000001812 153.0
PYH3_k127_3703488_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 2.509e-290 910.0
PYH3_k127_3703488_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 561.0
PYH3_k127_3703488_10 DNA ligase D, 3-phosphoesterase domain - - - 0.000000000000000000000000000000000000002267 149.0
PYH3_k127_3703488_11 Ribosomal protein S8e K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.000000000000000000000000000000002242 132.0
PYH3_k127_3703488_12 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000306 129.0
PYH3_k127_3703488_13 PFAM Aminotransferase class I and II K00812,K10907 - 2.6.1.1 0.000000000000000000000000000002664 136.0
PYH3_k127_3703488_14 - - - - 0.000000000000000000000000006318 119.0
PYH3_k127_3703488_15 Uncharacterized ArCR, COG1888 K09732 - - 0.000000000000000000000000208 108.0
PYH3_k127_3703488_16 hydrolase K01560 - 3.8.1.2 0.00000000000000000002073 101.0
PYH3_k127_3703488_17 PFAM Nickel cobalt transporter, high-affinity - - - 0.0000000000000000001249 101.0
PYH3_k127_3703488_18 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.00000000000000001174 93.0
PYH3_k127_3703488_19 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.000000000002126 70.0
PYH3_k127_3703488_2 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 443.0
PYH3_k127_3703488_20 Protein of unknown function (DUF3198) - - - 0.00000002801 60.0
PYH3_k127_3703488_3 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000006804 247.0
PYH3_k127_3703488_4 Cysteine-rich domain - - - 0.000000000000000000000000000000000000000000000000000000000000000002046 231.0
PYH3_k127_3703488_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043021,GO:0043022,GO:0044424,GO:0044464,GO:0044877 - 0.00000000000000000000000000000000000000000000000000000000000000001635 239.0
PYH3_k127_3703488_6 8-oxoguanine DNA glycosylase domain protein K03660 - 4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000006652 224.0
PYH3_k127_3703488_7 PFAM Appr-1-p processing - - - 0.000000000000000000000000000000000000000000000000000000007789 203.0
PYH3_k127_3703488_8 Predicted metal-binding protein (DUF2284) - - - 0.000000000000000000000000000000000000000000000000000000009793 203.0
PYH3_k127_3703488_9 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000001089 160.0
PYH3_k127_3794858_1 Transglutaminase-like superfamily - - - 0.0000000000000000003823 102.0
PYH3_k127_3832508_0 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.0000000000000000000000000000000000000000000000000000000000000000743 233.0
PYH3_k127_3832508_1 Cadherin repeats. - - - 0.0000000000000000000000000000000000000000001161 186.0
PYH3_k127_3832508_2 PFAM NHL repeat containing protein - - - 0.00000000000000000000000000007521 137.0
PYH3_k127_3832508_3 protein conserved in archaea - - - 0.00000000000000000000001055 104.0
PYH3_k127_3832508_4 PFAM Peptidase C1A, papain C-terminal - - - 0.000000004859 71.0
PYH3_k127_3832508_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000001108 70.0
PYH3_k127_3867331_0 conserved protein related to pyruvate formate-lyase activating enzyme K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002167 351.0
PYH3_k127_3867331_1 Belongs to the alpha-IPM synthase homocitrate synthase family K10977 - 2.3.3.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 328.0
PYH3_k127_3867331_10 but it may be involved in stabilization of the trimeric complex - - - 0.00000006157 55.0
PYH3_k127_3867331_11 ThiS family K03154 - - 0.0005723 46.0
PYH3_k127_3867331_2 Protein of unknown function (DUF1003) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001208 261.0
PYH3_k127_3867331_3 Phosphoribosyl transferase domain K00769,K07101 - 2.4.2.22 0.0000000000000000000000000000000000000000000000000000000000000000001188 237.0
PYH3_k127_3867331_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000005859 231.0
PYH3_k127_3867331_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family K04088,K06897 - 2.5.1.105 0.00000000000000000000000000000000000000000000000000000000001484 213.0
PYH3_k127_3867331_6 Belongs to the UPF0173 family - - - 0.00000000000000000000000000000000004545 142.0
PYH3_k127_3867331_7 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000005322 141.0
PYH3_k127_3867331_8 membrane - - - 0.00000000000000000000000000168 118.0
PYH3_k127_3867331_9 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000002395 90.0
PYH3_k127_3943259_0 PFAM Transketolase K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 388.0
PYH3_k127_3943259_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005751 385.0
PYH3_k127_3943259_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002231 376.0
PYH3_k127_3943259_3 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 321.0
PYH3_k127_3943259_4 Pyridoxal-dependent decarboxylase, pyridoxal binding domain K01581 - 4.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004385 321.0
PYH3_k127_3943259_5 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000002655 235.0
PYH3_k127_3943259_6 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000000009901 134.0
PYH3_k127_3943259_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000002516 127.0
PYH3_k127_3959534_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0 1026.0
PYH3_k127_3959534_1 PFAM Pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 4.823e-218 689.0
PYH3_k127_3959534_10 regulator of chromosome condensation, RCC1 - - - 0.0000002335 66.0
PYH3_k127_3959534_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002867 578.0
PYH3_k127_3959534_3 4-Hydroxyphenylpyruvate dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005997 410.0
PYH3_k127_3959534_4 TIGRFAM 2-oxoacid acceptor oxidoreductase, beta subunit, pyruvate 2-ketoisovalerate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 376.0
PYH3_k127_3959534_5 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000000008922 249.0
PYH3_k127_3959534_6 SCO1/SenC - - - 0.0000000000000000000000000000000000000000000000000000000008865 204.0
PYH3_k127_3959534_7 - K07092 - - 0.000000000000000000000000000000000000000000000006142 174.0
PYH3_k127_3959534_8 Rubrerythrin - - - 0.0000000000000000000000000000002579 129.0
PYH3_k127_3959534_9 pfam yhs - - - 0.00000000000000000302 85.0
PYH3_k127_3963015_0 PAC2 family K06869 - - 0.000000000000000000000000000000000000000000000000000000000000000000002086 244.0
PYH3_k127_3963015_1 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000000387 201.0
PYH3_k127_3963015_2 Pfam:KaiC K08482 - - 0.00000000000000000000000000000000000001398 163.0
PYH3_k127_3963015_3 Mut7-C RNAse domain K09122 - - 0.00000000000000000000002042 104.0
PYH3_k127_3990581_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 3.898e-223 704.0
PYH3_k127_3990581_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 594.0
PYH3_k127_3990581_2 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002024 479.0
PYH3_k127_3990581_3 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 447.0
PYH3_k127_3990581_4 Domain of unknown function (DUF4438) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 362.0
PYH3_k127_3990581_5 PP-loop family K21947 - 2.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 291.0
PYH3_k127_3990581_6 Psort location Cytoplasmic, score K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000004009 244.0
PYH3_k127_3990581_7 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000004491 161.0
PYH3_k127_4017426_0 Anticodon-binding domain of tRNA K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 4.212e-311 979.0
PYH3_k127_4017426_1 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001289 269.0
PYH3_k127_4017426_2 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001798 256.0
PYH3_k127_4017426_3 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02869 - - 0.00000000000000000000000000000005526 127.0
PYH3_k127_4017426_4 Periplasmic copper-binding protein (NosD) - - - 0.000000000000000000000009572 117.0
PYH3_k127_4017426_5 cellulase activity K01183,K01728 - 3.2.1.14,4.2.2.2 0.000000005513 69.0
PYH3_k127_4017426_6 ABC-2 type transporter K01992 - - 0.0000002078 56.0
PYH3_k127_4089993_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 1.772e-232 731.0
PYH3_k127_4089993_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005576 492.0
PYH3_k127_4089993_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000014 277.0
PYH3_k127_4089993_3 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000169 257.0
PYH3_k127_4089993_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002116 249.0
PYH3_k127_4089993_5 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000005173 227.0
PYH3_k127_4089993_6 - - - - 0.000000000000000000000000000000000000000000000000000000001122 219.0
PYH3_k127_4089993_7 Periplasmic copper-binding protein (NosD) - - - 0.00002931 57.0
PYH3_k127_4095385_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0 1022.0
PYH3_k127_4095385_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000000000000000000000000000002178 147.0
PYH3_k127_4095385_2 Conserved hypothetical ATP binding protein K06883 - - 0.00000000000000000000000000003027 118.0
PYH3_k127_4095385_3 Acylphosphatase - - - 0.0000001354 61.0
PYH3_k127_4095385_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0003288 50.0
PYH3_k127_4171084_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007225 576.0
PYH3_k127_4171084_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 504.0
PYH3_k127_4171084_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005193 343.0
PYH3_k127_4171084_3 PFAM PHP domain protein - - - 0.00000000000000000000000000000000000000002704 156.0
PYH3_k127_4243387_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1019.0
PYH3_k127_4243387_1 Cell division protein 48 (CDC48) domain 2 K13525 - - 9.524e-292 913.0
PYH3_k127_4243387_10 Membrane protein implicated in regulation of membrane protease activity - - - 0.0000000000000000000000000001235 121.0
PYH3_k127_4243387_11 PRC-barrel domain - - - 0.000000000000000000000006439 103.0
PYH3_k127_4243387_12 COG0589 Universal stress protein UspA and related nucleotide-binding proteins K20989 - - 0.0000000000000001909 84.0
PYH3_k127_4243387_13 von Willebrand factor, type A K07114 - - 0.00000000000004105 88.0
PYH3_k127_4243387_14 Pfam:DUF1628 - - - 0.0000000000006624 74.0
PYH3_k127_4243387_15 - - - - 0.000000000001161 73.0
PYH3_k127_4243387_16 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000004035 51.0
PYH3_k127_4243387_17 Pfam:DUF1628 - - - 0.00002139 53.0
PYH3_k127_4243387_2 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002172 531.0
PYH3_k127_4243387_3 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 433.0
PYH3_k127_4243387_4 Rad51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000048 276.0
PYH3_k127_4243387_5 (AIR) carboxylase K06898 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005228 276.0
PYH3_k127_4243387_6 Pfam:KaiC - - - 0.0000000000000000000000000000000000000000000000000000000001003 219.0
PYH3_k127_4243387_7 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.000000000000000000000000000000000000000000000006465 179.0
PYH3_k127_4243387_8 Membrane - - - 0.0000000000000000000000000000000000000000008544 167.0
PYH3_k127_4243387_9 COG1994 Zn-dependent proteases - - - 0.00000000000000000000000000000001559 135.0
PYH3_k127_4454556_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002689 438.0
PYH3_k127_4454556_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 297.0
PYH3_k127_4454556_2 LemA family K03744 - - 0.000000000000000000000000000000000008987 143.0
PYH3_k127_4454556_3 Methanol dehydrogenase K06872 - - 0.0000000000000000000000000001625 124.0
PYH3_k127_4454556_4 Polyprenyl synthetase K02523,K13787 - 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000001154 95.0
PYH3_k127_4506282_0 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008822 265.0
PYH3_k127_4506282_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000006484 239.0
PYH3_k127_4506282_2 Transcriptional regulator - - - 0.00000000000000000002847 94.0
PYH3_k127_4506282_3 Predicted membrane protein (DUF2318) - - - 0.0000000000000113 80.0
PYH3_k127_4506282_4 - - - - 0.000000000003304 75.0
PYH3_k127_4520257_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 410.0
PYH3_k127_4520257_1 FAD dependent oxidoreductase K00313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002908 356.0
PYH3_k127_4520257_2 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000001261 251.0
PYH3_k127_4520257_3 Electron transfer flavoprotein domain K03521 - - 0.00000000000000000000000000000000000000000000000827 181.0
PYH3_k127_4520257_4 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000004452 165.0
PYH3_k127_4520257_5 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K03855 - - 0.0000000000000000000000001115 116.0
PYH3_k127_4520257_6 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.000000000231 64.0
PYH3_k127_4520257_7 Electron transfer flavoprotein domain K03522 - - 0.0000112 53.0
PYH3_k127_4527875_0 Belongs to the carbamoyltransferase HypF family K04656 - - 7.609e-239 760.0
PYH3_k127_4527875_1 AAA domain K01338 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 598.0
PYH3_k127_4527875_10 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000001661 195.0
PYH3_k127_4527875_11 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.00000000000000000000000000006222 121.0
PYH3_k127_4527875_12 Tetratricopeptide TPR_2 repeat protein - - - 0.0000000000000000000004002 113.0
PYH3_k127_4527875_13 Periplasmic copper-binding protein (NosD) - - - 0.00000000000001939 88.0
PYH3_k127_4527875_14 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.000000000001737 74.0
PYH3_k127_4527875_15 PFAM hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.000000000008435 70.0
PYH3_k127_4527875_16 Acetyltransferase (GNAT) domain - - - 0.0000000009404 66.0
PYH3_k127_4527875_17 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000001149 57.0
PYH3_k127_4527875_18 Pfam:DUF1628 - - - 0.00002238 53.0
PYH3_k127_4527875_2 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 501.0
PYH3_k127_4527875_3 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 467.0
PYH3_k127_4527875_4 Toprim domain K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 432.0
PYH3_k127_4527875_5 hydrogenase expression formation protein HypD K04654 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 332.0
PYH3_k127_4527875_6 PFAM AIR synthase related protein K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 324.0
PYH3_k127_4527875_7 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.000000000000000000000000000000000000000000000000000000000000001762 230.0
PYH3_k127_4527875_8 Helix-turn-helix XRE-family like proteins K07731 - - 0.000000000000000000000000000000000000000000000000000000000000008966 223.0
PYH3_k127_4527875_9 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.000000000000000000000000000000000000000000000009475 176.0
PYH3_k127_4546034_0 aspartate--ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 557.0
PYH3_k127_4546034_1 Alcohol dehydrogenase GroES-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 414.0
PYH3_k127_4546034_2 DeoC/LacD family aldolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 398.0
PYH3_k127_4546034_3 PFAM GAF domain K08968 - 1.8.4.14 0.00000000000000000000000000000000000000000000002111 175.0
PYH3_k127_4546034_4 Thioredoxin K03671 - - 0.0000000000000000000000000000002278 127.0
PYH3_k127_4546034_5 COG1361 S-layer domain - - - 0.00000000000000000001015 102.0
PYH3_k127_4546034_6 PFAM NHL repeat containing protein - - - 0.000000000000000001915 101.0
PYH3_k127_4546034_7 Protein of unknown function (DUF835) - - - 0.00000005498 61.0
PYH3_k127_4546034_8 TIGRFAM RHS repeat-associated core domain - - - 0.000005521 60.0
PYH3_k127_4546034_9 transcriptional regulators - - - 0.0007066 46.0
PYH3_k127_4642444_0 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 318.0
PYH3_k127_4642444_1 Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase K07559 - - 0.000000000000000000000000000000000000000000000000000000000000000000005194 240.0
PYH3_k127_4642444_2 - - - - 0.0000000000000000000000001289 122.0
PYH3_k127_4642444_3 SpoVT / AbrB like domain - - - 0.00000000000000222 81.0
PYH3_k127_4670545_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 310.0
PYH3_k127_4670545_1 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006701 276.0
PYH3_k127_4670545_2 Transposase IS200 like K07491 - - 0.00000000000000000005693 101.0
PYH3_k127_4685642_0 PFAM Hydantoinase B oxoprolinase K01474 - 3.5.2.14 6.421e-285 902.0
PYH3_k127_4685642_1 PFAM Hydantoinase oxoprolinase K01473 - 3.5.2.14 3.039e-283 887.0
PYH3_k127_4685642_2 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002827 365.0
PYH3_k127_4685642_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 310.0
PYH3_k127_4685642_4 Calcineurin-like phosphoesterase superfamily domain K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000002455 239.0
PYH3_k127_4685642_5 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000005957 211.0
PYH3_k127_4685642_6 - - - - 0.000000000000000000000000000000000000000009012 155.0
PYH3_k127_4685642_7 NAD dependent epimerase/dehydratase family K00059 - 1.1.1.100 0.000000000000000000000000005344 113.0
PYH3_k127_4696936_0 DEAD/H associated K03724 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008732 420.0
PYH3_k127_4696936_1 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000955 379.0
PYH3_k127_4696936_2 TPR Domain containing protein - - - 0.000000000000000000000000000001473 139.0
PYH3_k127_4779715_0 pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001451 479.0
PYH3_k127_4779715_1 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003011 425.0
PYH3_k127_4779715_10 transcriptional regulator, ArsR family K07013 - - 0.0000000000007446 80.0
PYH3_k127_4779715_11 cell adhesion - - - 0.00002636 58.0
PYH3_k127_4779715_2 PFAM thiamine pyrophosphate protein domain protein TPP-binding K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 291.0
PYH3_k127_4779715_3 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004393 278.0
PYH3_k127_4779715_4 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000005465 203.0
PYH3_k127_4779715_5 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000000000000009993 215.0
PYH3_k127_4779715_6 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000000005989 215.0
PYH3_k127_4779715_7 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000006658 152.0
PYH3_k127_4779715_8 4Fe-4S dicluster domain K00338 - 1.6.5.3 0.000000000000000000007915 98.0
PYH3_k127_4779715_9 Transcriptional regulator, TrmB - - - 0.00000000000000000002886 104.0
PYH3_k127_4961204_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000505 279.0
PYH3_k127_4961204_1 ABC transporter K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000002271 205.0
PYH3_k127_4961204_2 Regulatory protein Crp K07730 - - 0.000000000000000000000000000000003385 145.0
PYH3_k127_4987453_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 355.0
PYH3_k127_4987453_1 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 318.0
PYH3_k127_4987453_10 Glycosyltransferase Family 4 - - - 0.0000000000000000000000000001118 131.0
PYH3_k127_4987453_11 Transcriptional regulator, ArsR family - - - 0.00000000000000000000001855 108.0
PYH3_k127_4987453_12 Tetratricopeptide repeat - - - 0.00000000000000202 90.0
PYH3_k127_4987453_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000003962 75.0
PYH3_k127_4987453_14 PFAM Ribosomal LX protein K02944 - - 0.0000000000704 65.0
PYH3_k127_4987453_15 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0016272,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0032991,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 0.00001281 53.0
PYH3_k127_4987453_2 D-aminopeptidase K16203 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006045 274.0
PYH3_k127_4987453_3 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0003896,GO:0003899,GO:0005488,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006269,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901363,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002654 277.0
PYH3_k127_4987453_4 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000001715 232.0
PYH3_k127_4987453_5 and related - - - 0.000000000000000000000000000000000000000000000000000000000000006469 227.0
PYH3_k127_4987453_6 Elongator protein 3, MiaB family, Radical SAM K09711 - - 0.000000000000000000000000000000000000000000000000003163 192.0
PYH3_k127_4987453_7 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000000007815 196.0
PYH3_k127_4987453_8 haloacid dehalogenase-like hydrolase K01079 - 3.1.3.3 0.0000000000000000000000000000000000001688 149.0
PYH3_k127_4987453_9 homolog of PrgY (pheromone shutdown protein) - - - 0.00000000000000000000000000000004699 134.0
PYH3_k127_4990875_0 modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005694 452.0
PYH3_k127_4990875_1 modulator of DNA gyrase K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001702 284.0
PYH3_k127_4992259_0 Tetratricopeptide repeat - - - 0.0000000000000000009418 97.0
PYH3_k127_4992259_1 Transcriptional regulators - - - 0.000000001507 63.0
PYH3_k127_4992493_0 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000571 335.0
PYH3_k127_4992493_1 protein conserved in archaea K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.000000000001452 76.0
PYH3_k127_4992493_2 Binds the lower part of the 30S subunit head K02982 - - 0.000475 51.0
PYH3_k127_501286_0 helicase superfamily c-terminal domain K10896 - - 1.777e-220 709.0
PYH3_k127_501286_1 PFAM Aminotransferase, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 302.0
PYH3_k127_501286_2 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009218 274.0
PYH3_k127_501286_3 DnaB-like helicase C terminal domain - - - 0.00000000000000000000009969 106.0
PYH3_k127_501286_4 Sugar (and other) transporter - - - 0.00000000000000007276 93.0
PYH3_k127_501286_5 COGs COG1373 ATPase (AAA superfamily) K07133 - - 0.00000000003148 69.0
PYH3_k127_501286_6 - - - - 0.0000000001164 64.0
PYH3_k127_501286_7 Double zinc ribbon - - - 0.0002358 53.0
PYH3_k127_5047894_0 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 589.0
PYH3_k127_5047894_1 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.000000000000000000000000000000000001069 144.0
PYH3_k127_5062119_0 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000000000000000000000002879 199.0
PYH3_k127_5062119_1 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000004574 182.0
PYH3_k127_5062119_2 Binds to the 50S ribosomal subunit and prevents its association with the 30S ribosomal subunit to form the 70S initiation complex K03264 - - 0.0000000000000000000000000000000000000000000000001134 184.0
PYH3_k127_5062119_3 Belongs to the PDCD5 family K06875 - - 0.00000000000000000000000008798 109.0
PYH3_k127_5062119_4 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000006529 95.0
PYH3_k127_5062119_5 Belongs to the eukaryotic ribosomal protein eL39 family K02924 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000001444 77.0
PYH3_k127_5062119_6 PFAM NHL repeat containing protein - - - 0.00000009774 59.0
PYH3_k127_5072838_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate K07558 - 2.7.7.72 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003839 333.0
PYH3_k127_5072838_1 ribosomal small subunit binding - - - 0.0001952 50.0
PYH3_k127_5111935_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 462.0
PYH3_k127_5111935_1 able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 430.0
PYH3_k127_5111935_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000002844 239.0
PYH3_k127_5111935_3 MobA-like NTP transferase domain K00966 - 2.7.7.13 0.000000000000000000000000000000000000000000000000002342 195.0
PYH3_k127_5111935_4 PAC2 family K06869 - - 0.00000000000000000000000000000000000000000000000004536 187.0
PYH3_k127_5111935_5 Belongs to the eukaryotic ribosomal protein eS1 family K02984 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000001537 173.0
PYH3_k127_5111935_6 snRNP Sm proteins K04796 - - 0.00000000000000000006187 91.0
PYH3_k127_5111935_7 Parallel beta-helix repeats - - - 0.000000000000000001979 94.0
PYH3_k127_5111935_8 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.00000000000000005488 84.0
PYH3_k127_5219975_0 PFAM Glycosyl transferase, group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 325.0
PYH3_k127_5219975_1 Benzoyl-CoA reductase 2-hydroxyglutaryl-CoA dehydratase subunit BcrC BadD HgdB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009098 287.0
PYH3_k127_5219975_2 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000001933 122.0
PYH3_k127_5219975_3 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000001962 109.0
PYH3_k127_5219975_4 4Fe-4S binding domain protein - - - 0.0000000000001756 72.0
PYH3_k127_5237939_0 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000003127 199.0
PYH3_k127_5237939_1 TPR Domain containing protein - - - 0.0000000000000003054 94.0
PYH3_k127_5276618_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.191e-302 957.0
PYH3_k127_5276618_1 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.902e-245 769.0
PYH3_k127_5276618_10 Belongs to the 4-oxalocrotonate tautomerase family K01821 - 5.3.2.6 0.0000000008558 61.0
PYH3_k127_5276618_11 Methyltransferase - - - 0.000000002912 68.0
PYH3_k127_5276618_12 - K07341 - - 0.00000033 57.0
PYH3_k127_5276618_13 - - - - 0.0000004443 56.0
PYH3_k127_5276618_14 Belongs to the glycosyl hydrolase 13 family - - - 0.00002476 56.0
PYH3_k127_5276618_2 Formiminotransferase-cyclodeaminase K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009241 359.0
PYH3_k127_5276618_3 CobB/CobQ-like glutamine amidotransferase domain K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002344 263.0
PYH3_k127_5276618_4 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.00000000000000000000000000000000000000000000000000000000000006674 221.0
PYH3_k127_5276618_5 Bacterial regulatory helix-turn-helix protein, lysR family K03574 - 3.6.1.55 0.000000000000000000000000000000000000000000000000001184 199.0
PYH3_k127_5276618_6 PFAM tRNA methyltransferase complex GCD14 subunit K07442 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0031515,GO:0032991,GO:0034708,GO:0043527,GO:0044424,GO:0044444,GO:0044464,GO:1902494,GO:1990234 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000001013 177.0
PYH3_k127_5276618_7 cyclohydrolase K01746 - 4.3.1.4 0.00000000000000000000000000000000000000000007615 169.0
PYH3_k127_5276618_8 Fcf1 K07158 - - 0.000000000000000001922 89.0
PYH3_k127_5276618_9 Lrp/AsnC ligand binding domain - - - 0.000000000003382 69.0
PYH3_k127_5338352_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 4.859e-247 788.0
PYH3_k127_5338352_1 Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2 K03243 - - 5.009e-219 693.0
PYH3_k127_5338352_10 ParB-like nuclease domain - - - 0.00000000000000000000000008977 111.0
PYH3_k127_5338352_11 Arsenical resistance operon trans-acting repressor ArsD - - - 0.000000000000000000000002822 106.0
PYH3_k127_5338352_12 DGC domain - - - 0.0000000000000000000001796 102.0
PYH3_k127_5338352_13 Belongs to the UPF0218 family K09735 - - 0.0000000000000000000004898 103.0
PYH3_k127_5338352_14 PRC-barrel domain - - - 0.0000000000000000001005 93.0
PYH3_k127_5338352_15 - - - - 0.0000000000000000001378 93.0
PYH3_k127_5338352_16 PFAM regulatory protein, ArsR K21903 - - 0.0000000000000000002554 91.0
PYH3_k127_5338352_17 Acetyltransferase (GNAT) domain - - - 0.0000000000000002547 89.0
PYH3_k127_5338352_18 Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro - - - 0.0000000000000002586 93.0
PYH3_k127_5338352_19 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.0000000000000007111 81.0
PYH3_k127_5338352_2 COG0003 Oxyanion-translocating ATPase K01551 - 3.6.3.16 5.825e-209 670.0
PYH3_k127_5338352_20 cobalamin transport - - - 0.000000000000008454 89.0
PYH3_k127_5338352_21 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000001557 74.0
PYH3_k127_5338352_22 PFAM regulatory protein, ArsR - - - 0.000000000004278 76.0
PYH3_k127_5338352_23 - - - - 0.00000000005491 68.0
PYH3_k127_5338352_24 alginic acid biosynthetic process K01729,K17713 - 4.2.2.3 0.00000002003 68.0
PYH3_k127_5338352_25 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000002173 59.0
PYH3_k127_5338352_3 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002409 419.0
PYH3_k127_5338352_4 Peptidase family M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 379.0
PYH3_k127_5338352_5 COG0488 ATPase components of ABC transporters with duplicated ATPase domains K06158 - - 0.0000000000000000000000000000000000000000000000000000000000000000002412 244.0
PYH3_k127_5338352_6 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000001717 212.0
PYH3_k127_5338352_7 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000001442 169.0
PYH3_k127_5338352_8 PKD domain - - - 0.000000000000000000000000001736 130.0
PYH3_k127_5338352_9 Putative Fe-S cluster - - - 0.0000000000000000000000000027 121.0
PYH3_k127_535288_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007371 610.0
PYH3_k127_535288_1 Glycine cleavage system P-protein K00282 - 1.4.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001234 445.0
PYH3_k127_535288_2 Domain of unknown function (DUF373) K08975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005552 251.0
PYH3_k127_535288_3 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000002993 219.0
PYH3_k127_535288_4 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.000000000000000000000000000000000000000000000003259 193.0
PYH3_k127_535288_5 PFAM GGDEF domain containing protein - - - 0.0003865 49.0
PYH3_k127_5410648_0 UDP-N-acetylglucosamine 2-epimerase K01791 - 5.1.3.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005165 422.0
PYH3_k127_5410648_1 PFAM methyltransferase small K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044464 2.1.1.297 0.0000000000000000000000000001534 124.0
PYH3_k127_5410648_2 PFAM Rhomboid family protein - - - 0.000000000000000001907 96.0
PYH3_k127_5431496_0 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.242e-267 856.0
PYH3_k127_5431496_1 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006481 471.0
PYH3_k127_5431496_10 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000000000175 200.0
PYH3_k127_5431496_11 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.0000000000000000000000000000000000000000000000000000468 203.0
PYH3_k127_5431496_12 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000001328 178.0
PYH3_k127_5431496_13 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000000000002205 106.0
PYH3_k127_5431496_14 Glucose / Sorbosone dehydrogenase - - - 0.0000004067 64.0
PYH3_k127_5431496_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000163 406.0
PYH3_k127_5431496_3 Dehydrogenase K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005298 372.0
PYH3_k127_5431496_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 350.0
PYH3_k127_5431496_5 deoxyribonuclease I activity K06131,K06915 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001681 345.0
PYH3_k127_5431496_6 PFAM Cysteine-rich domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002924 319.0
PYH3_k127_5431496_7 PFAM histone deacetylase superfamily K04768 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 319.0
PYH3_k127_5431496_8 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001141 282.0
PYH3_k127_5431496_9 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.000000000000000000000000000000000000000000000000000000008688 218.0
PYH3_k127_5437253_0 Hydrolyase tartrate alpha subunit fumarate domain protein Fe-S type K01677 - 4.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006946 368.0
PYH3_k127_5437253_1 AP endonuclease family 2 K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 297.0
PYH3_k127_5437253_2 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 315.0
PYH3_k127_5437253_3 PFAM PKD domain containing protein K11751 - 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000002456 277.0
PYH3_k127_5437253_4 Fe-S type, tartrate fumarate subfamily, beta K01678 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000001118 252.0
PYH3_k127_5437253_5 S-adenosyl-L-methionine-dependent transferase that acts as a component of the wyosine derivatives biosynthesis pathway. Catalyzes the transfer of the alpha-amino-alpha-carboxypropyl (acp) group from S-adenosyl-L-methionine to 4-demethylwyosine (imG-14), forming 7-aminocarboxypropyl-demethylwyosine (wybutosine-86) at position 37 of tRNA(Phe) K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.00000000000000000000000000000000000000000000000000000000001754 213.0
PYH3_k127_5437253_6 O-methyltransferase - - - 0.00000000000000000000000000000000000000001668 165.0
PYH3_k127_5437253_7 cellulase activity - - - 0.0001023 56.0
PYH3_k127_5512245_0 Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD) K09739 - 4.1.2.25 0.000000000000000000000000000000000000008407 151.0
PYH3_k127_5512245_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.000000000000000000000000000001588 128.0
PYH3_k127_5512245_2 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.0000000000000000000000000002375 125.0
PYH3_k127_5512245_3 Domain of unknown function - - - 0.000000005303 58.0
PYH3_k127_5522367_0 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 317.0
PYH3_k127_5522367_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007519 275.0
PYH3_k127_5522367_2 COG0110 Acetyltransferase (isoleucine patch superfamily) - - - 0.0000000000000000000000000000000000000000000000002835 181.0
PYH3_k127_5527775_0 Catalyzes the conversion of AMP and phosphate to adenine and ribose 1,5-bisphosphate (R15P). Exhibits phosphorylase activity toward CMP and UMP in addition to AMP. Functions in an archaeal AMP degradation pathway, together with R15P isomerase and RubisCO K18931 GO:0000166,GO:0003674,GO:0003824,GO:0004645,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006195,GO:0006196,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009123,GO:0009125,GO:0009126,GO:0009128,GO:0009150,GO:0009154,GO:0009158,GO:0009161,GO:0009166,GO:0009167,GO:0009169,GO:0009259,GO:0009261,GO:0009987,GO:0016208,GO:0016740,GO:0016757,GO:0016758,GO:0016763,GO:0017076,GO:0017144,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0036094,GO:0042301,GO:0042737,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046033,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:0097159,GO:0097367,GO:1901135,GO:1901136,GO:1901265,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576 2.4.2.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 497.0
PYH3_k127_5527775_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000005271 151.0
PYH3_k127_5527775_2 AAA domain - - - 0.0000000000000000000000000000000000006395 158.0
PYH3_k127_5527775_3 PFAM HhH-GPD K07457 - - 0.00000001411 56.0
PYH3_k127_5543429_0 Involved in regulation of DNA replication K10725 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 438.0
PYH3_k127_5543429_1 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 470.0
PYH3_k127_5543429_10 Signal peptidase K13280 - 3.4.21.89 0.000000000000000000000000000000001622 147.0
PYH3_k127_5543429_11 anaphase-promoting complex binding K03466,K06196,K12132 - 2.7.11.1 0.000000000000000000000000002115 133.0
PYH3_k127_5543429_12 PFAM Methyltransferase type 11 - - - 0.000000000000000000000000006062 120.0
PYH3_k127_5543429_13 Protein of unknown function (DUF402) K09145 - - 0.0000000000000000000013 101.0
PYH3_k127_5543429_14 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000008664 90.0
PYH3_k127_5543429_15 Endonuclease Exonuclease Phosphatase - - - 0.00000000000000002264 94.0
PYH3_k127_5543429_16 PFAM CBS domain containing protein - - - 0.00000000000000007085 94.0
PYH3_k127_5543429_17 PFAM CMP dCMP deaminase zinc-binding K01493 - 3.5.4.12 0.000000000000000297 89.0
PYH3_k127_5543429_18 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000298 79.0
PYH3_k127_5543429_19 PFAM plasmid stabilization system K06218 - - 0.00000000001872 67.0
PYH3_k127_5543429_2 Succinyl-CoA ligase like flavodoxin domain K18594 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 385.0
PYH3_k127_5543429_20 enzyme 1 K12165 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0019538,GO:0019787,GO:0032446,GO:0033554,GO:0034976,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0070647,GO:0071568,GO:0071569,GO:0071704,GO:0140096,GO:1901564,GO:1990564,GO:1990592 - 0.00000000002707 70.0
PYH3_k127_5543429_21 Belongs to the peptidase S8 family K01361,K08652,K14647 GO:0005575,GO:0005576 3.4.21.110,3.4.21.96 0.00000005517 68.0
PYH3_k127_5543429_22 Serine protease with a broad substrate specificity K17734 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005488,GO:0005509,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0046872,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000003374 63.0
PYH3_k127_5543429_23 COG3420 Nitrous oxidase accessory protein K07218 - - 0.000007811 56.0
PYH3_k127_5543429_25 - - - - 0.00002283 49.0
PYH3_k127_5543429_26 amine dehydrogenase activity - - - 0.00009065 58.0
PYH3_k127_5543429_3 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 371.0
PYH3_k127_5543429_4 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 327.0
PYH3_k127_5543429_5 ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000168 287.0
PYH3_k127_5543429_6 ABC-2 type transporter K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008348 269.0
PYH3_k127_5543429_7 ThiF family K12164 - - 0.00000000000000000000000000000000000000000000000000000485 204.0
PYH3_k127_5543429_8 Pkd domain containing protein - - - 0.0000000000000000000000000000000000000000000001716 194.0
PYH3_k127_5543429_9 COG0500 SAM-dependent methyltransferases - - - 0.0000000000000000000000000000000000000000000177 175.0
PYH3_k127_5633153_0 PFAM Radical SAM domain protein K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 390.0
PYH3_k127_5633153_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000002109 229.0
PYH3_k127_5633153_2 aminopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000005537 225.0
PYH3_k127_5633153_3 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000001938 235.0
PYH3_k127_5633153_4 PFAM GvpD gas vesicle - - - 0.00000000000000000000000000000000000000000000000000009591 205.0
PYH3_k127_5633153_5 Roadblock LC7 family protein K07131 - - 0.0000000000000001034 84.0
PYH3_k127_5655996_0 Ferrous iron transport B domain protein K04759 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 580.0
PYH3_k127_5655996_1 FeoA K03709 - - 0.0000000000000000000000000000000000000000000000000000000000000000005162 235.0
PYH3_k127_5655996_2 PFAM ATP corrinoid adenosyltransferase BtuR CobO CobP K19221 - 2.5.1.17 0.000000000000000000000000000000000000000000000000002701 187.0
PYH3_k127_5655996_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000003819 174.0
PYH3_k127_5655996_4 Transcriptional regulator, AbiEi antitoxin - - - 0.0000000000000000000000000000000000009195 148.0
PYH3_k127_5655996_5 Nucleotidyl transferase AbiEii toxin, Type IV TA system K09144 - - 0.000000000000000000000000000000000004523 146.0
PYH3_k127_5655996_6 CAAX protease self-immunity - - - 0.0000000000000000000000000002171 128.0
PYH3_k127_5655996_7 Copper binding proteins, plastocyanin/azurin family - - - 0.0000000000000000000001949 100.0
PYH3_k127_5655996_8 - - - - 0.00000001316 66.0
PYH3_k127_5655996_9 Protein of unknown function (DUF835) - - - 0.0009008 48.0
PYH3_k127_5778245_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 GO:0000502,GO:0003674,GO:0003824,GO:0003924,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0022623,GO:0022624,GO:0030163,GO:0032991,GO:0043170,GO:0043273,GO:0043335,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 492.0
PYH3_k127_5778245_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 330.0
PYH3_k127_5778245_10 Ribosomal protein S27E K02978 - - 0.000000000000437 76.0
PYH3_k127_5778245_11 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.00000000000457 68.0
PYH3_k127_5778245_12 toxin-antitoxin pair type II binding - - - 0.000000313 56.0
PYH3_k127_5778245_2 PAC2 family K07159 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001131 282.0
PYH3_k127_5778245_3 Binds to the 23S rRNA K02929 - - 0.00000000000000000000000000000000001265 137.0
PYH3_k127_5778245_4 Transcriptional regulator, ArsR family - - - 0.000000000000000000000000009095 117.0
PYH3_k127_5778245_5 Uncharacterized protein conserved in archaea (DUF2240) - - - 0.00000000000000000000402 101.0
PYH3_k127_5778245_6 PAS domain K02488 - 2.7.7.65 0.000000000000001804 85.0
PYH3_k127_5778245_7 nucleic acid-binding protein contains PIN domain K07063 - - 0.000000000000001939 79.0
PYH3_k127_5778245_8 S-layer homology domain - - - 0.0000000000000172 83.0
PYH3_k127_5778245_9 Helix-turn-helix domain K03627 - - 0.0000000000001282 79.0
PYH3_k127_5796686_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 4.881e-239 767.0
PYH3_k127_5796686_1 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002391 346.0
PYH3_k127_5796686_2 - - - - 0.00000000000000000000000000002927 119.0
PYH3_k127_5796686_3 Predicted membrane protein (DUF2085) - - - 0.00000000000000003794 87.0
PYH3_k127_5820630_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1061.0
PYH3_k127_5820630_1 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 4.521e-198 625.0
PYH3_k127_5820630_10 SMART Tetratricopeptide repeat - - - 0.00000001954 66.0
PYH3_k127_5820630_11 Parallel beta-helix repeats - - - 0.0007699 53.0
PYH3_k127_5820630_2 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006031 355.0
PYH3_k127_5820630_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002046 229.0
PYH3_k127_5820630_4 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000002723 210.0
PYH3_k127_5820630_5 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000003001 174.0
PYH3_k127_5820630_6 With S4 and S5 plays an important role in translational accuracy. Located at the interface of the 30S and 50S subunits K02950 - - 0.00000000000000000000000000000000000000007716 151.0
PYH3_k127_5820630_7 cellulase activity - - - 0.000000000000000000000000000000000215 153.0
PYH3_k127_5820630_8 Papain family cysteine protease - - - 0.0000000000000002162 95.0
PYH3_k127_5820630_9 PFAM PKD domain containing protein - - - 0.000000000002543 81.0
PYH3_k127_5836906_0 Pfam:DUF650 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006232 531.0
PYH3_k127_5836906_1 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 533.0
PYH3_k127_5836906_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000001398 238.0
PYH3_k127_5836906_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000001407 199.0
PYH3_k127_5836906_4 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000001771 113.0
PYH3_k127_5836906_5 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000004061 97.0
PYH3_k127_584733_0 FtsX-like permease family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004148 287.0
PYH3_k127_584733_1 Integrin alpha (beta-propellor repeats). - - - 0.00000000000000000000000000002236 138.0
PYH3_k127_584733_2 PFAM NHL repeat containing protein - - - 0.00000000000000000007655 106.0
PYH3_k127_584733_3 guanyl-nucleotide exchange factor activity K01406,K20276,K21449 - 3.4.24.40 0.0000000000000000001974 105.0
PYH3_k127_584733_4 to Saccharomyces cerevisiae RPN11 (YFR004W) K03030 GO:0000266,GO:0000502,GO:0003674,GO:0003824,GO:0004843,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005739,GO:0005829,GO:0005838,GO:0006464,GO:0006508,GO:0006511,GO:0006807,GO:0006996,GO:0007005,GO:0007031,GO:0007088,GO:0007346,GO:0008150,GO:0008152,GO:0008233,GO:0008234,GO:0008237,GO:0008541,GO:0009056,GO:0009057,GO:0009896,GO:0009987,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0016043,GO:0016559,GO:0016579,GO:0016787,GO:0019538,GO:0019783,GO:0019941,GO:0022607,GO:0022624,GO:0030071,GO:0030163,GO:0031331,GO:0031597,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034515,GO:0034622,GO:0036211,GO:0036459,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043248,GO:0043412,GO:0043632,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0045732,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045931,GO:0048285,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051128,GO:0051130,GO:0051247,GO:0051603,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0062033,GO:0065003,GO:0065007,GO:0070011,GO:0070013,GO:0070646,GO:0070647,GO:0071704,GO:0071840,GO:0090068,GO:0101005,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1902906,GO:1903052,GO:1903364,GO:1905368,GO:1905369,GO:1905818,GO:1905820,GO:2001252 - 0.00000000009943 68.0
PYH3_k127_584733_5 PFAM membrane-flanked domain - - - 0.000000001374 68.0
PYH3_k127_584733_6 amine dehydrogenase activity - - - 0.00005911 57.0
PYH3_k127_5867859_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009937 419.0
PYH3_k127_5867859_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 GO:0003674,GO:0003824,GO:0004164,GO:0006417,GO:0006448,GO:0006464,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009056,GO:0009058,GO:0009109,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0010608,GO:0016740,GO:0016741,GO:0017144,GO:0017182,GO:0017183,GO:0018193,GO:0018202,GO:0019222,GO:0019538,GO:0031323,GO:0031326,GO:0032259,GO:0032268,GO:0034248,GO:0036211,GO:0042737,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044273,GO:0046500,GO:0050789,GO:0050794,GO:0050843,GO:0051171,GO:0051186,GO:0051187,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:1900247,GO:1901564,GO:1901575,GO:2000112,GO:2000765 2.1.1.98 0.000000000000000000000000000000000000000000000000000000000000006549 224.0
PYH3_k127_5867859_2 PFAM metallophosphoesterase K06953 - - 0.0000000000000000000000000000000000000000004703 166.0
PYH3_k127_5867859_3 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.00000000000000000000000000005019 118.0
PYH3_k127_6041493_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0022616,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0042575,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0061695,GO:0071704,GO:0090304,GO:1901360,GO:1901576,GO:1902494,GO:1990234 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 386.0
PYH3_k127_6041493_1 FMN binding - - - 0.000000000000000000000000000000000003382 145.0
PYH3_k127_6041493_2 Belongs to the UPF0201 family K09736 - - 0.000000000000005022 80.0
PYH3_k127_6041493_3 PFAM YcfA-like protein - - - 0.00000000000001334 76.0
PYH3_k127_6041493_4 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000005386 65.0
PYH3_k127_605271_0 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000000000000000000000000000000000000000000001166 207.0
PYH3_k127_605271_1 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.00000000000000000000000000000000000000002793 160.0
PYH3_k127_6054075_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 3.075e-235 744.0
PYH3_k127_6054075_1 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 481.0
PYH3_k127_6054075_10 Type II/IV secretion system protein K07332 - - 0.0000000000000004094 89.0
PYH3_k127_6054075_11 transposition, DNA-mediated - - - 0.000000000007721 69.0
PYH3_k127_6054075_2 Catalyzes the conversion of dihydroorotate to orotate K00254,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009573 346.0
PYH3_k127_6054075_3 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002961 261.0
PYH3_k127_6054075_4 T4-like virus tail tube protein gp19 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003028 243.0
PYH3_k127_6054075_5 Belongs to the purine pyrimidine phosphoribosyltransferase family K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000005266 233.0
PYH3_k127_6054075_6 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000002956 253.0
PYH3_k127_6054075_7 ATPase (AAA superfamily K07133 - - 0.000000000000000000000000000000000000000000008949 179.0
PYH3_k127_6054075_8 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000001786 157.0
PYH3_k127_6054075_9 - - - - 0.000000000000000000003801 106.0
PYH3_k127_6139510_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.0 1165.0
PYH3_k127_6139510_1 Cysteine desulfurase K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 385.0
PYH3_k127_6139510_2 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 370.0
PYH3_k127_6139510_3 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 317.0
PYH3_k127_6139510_4 membrane protein, required for N-linked glycosylation K07151 GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.99.18 0.00000000000000000000000002096 125.0
PYH3_k127_6139510_5 PFAM glycosyl transferase group 1 - - - 0.000000000000000000001274 106.0
PYH3_k127_6139510_6 exo-alpha-(2->6)-sialidase activity - - - 0.000000008014 65.0
PYH3_k127_6143165_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004343 549.0
PYH3_k127_6143165_1 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007509 496.0
PYH3_k127_6143165_2 oligoendopeptidase F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 376.0
PYH3_k127_6143165_3 tRNA intron endonuclease, catalytic C-terminal domain K01170 GO:0000213,GO:0000379,GO:0000394,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0004549,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016892,GO:0016894,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:0140101,GO:1901360 4.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008612 302.0
PYH3_k127_6143165_4 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000008777 106.0
PYH3_k127_6143165_5 - - - - 0.000000000000000000001732 97.0
PYH3_k127_6143165_6 Endonuclease I - - - 0.0000000000000007913 91.0
PYH3_k127_6143165_7 Double zinc ribbon - - - 0.0000000000002602 79.0
PYH3_k127_6143165_8 RNA-binding protein involved in rRNA processing K07569 - - 0.000003982 53.0
PYH3_k127_6143165_9 - - - - 0.0000924 48.0
PYH3_k127_6264418_0 PFAM formate-tetrahydrofolate ligase FTHFS K01938 - 6.3.4.3 7.733e-238 751.0
PYH3_k127_6264418_1 PFAM Respiratory-chain NADH dehydrogenase domain 51 kDa subunit K00335 - 1.6.5.3 3.063e-228 729.0
PYH3_k127_6264418_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 370.0
PYH3_k127_6264418_3 PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000001481 166.0
PYH3_k127_6264418_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299,K22341 - 1.17.1.10,1.17.1.11,1.17.1.9 0.0000000000000000002306 89.0
PYH3_k127_6300096_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 4.127e-297 925.0
PYH3_k127_6300096_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 2.018e-222 708.0
PYH3_k127_6300096_10 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000003903 199.0
PYH3_k127_6300096_11 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000006957 215.0
PYH3_k127_6300096_12 Probable molybdopterin binding domain K03638 - 2.7.7.75 0.00000000000000000000000000000000000000000000001986 176.0
PYH3_k127_6300096_13 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000002608 175.0
PYH3_k127_6300096_14 Electron transfer flavoprotein domain K03521 - - 0.000000000000000000000000000000000000000000003581 175.0
PYH3_k127_6300096_15 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000897 165.0
PYH3_k127_6300096_16 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.0000000000000000000000000000008066 128.0
PYH3_k127_6300096_17 spore germination K00442,K03605,K04656,K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.000000000000000000000000000001402 126.0
PYH3_k127_6300096_18 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000002762 72.0
PYH3_k127_6300096_19 Fibronectin type III domain - - - 0.00003101 58.0
PYH3_k127_6300096_2 PFAM fumarate reductase succinate dehydrogenase flavoprotein K00239 - 1.3.5.1,1.3.5.4 3.931e-205 660.0
PYH3_k127_6300096_3 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 549.0
PYH3_k127_6300096_4 Fibronectin type III domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002003 486.0
PYH3_k127_6300096_5 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002871 411.0
PYH3_k127_6300096_6 TIGRFAM molybdenum cofactor synthesis domain K03750,K07219 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006464,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009144,GO:0009150,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0018315,GO:0019538,GO:0019637,GO:0019693,GO:0019720,GO:0032324,GO:0034641,GO:0036211,GO:0042040,GO:0042278,GO:0043170,GO:0043412,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044464,GO:0046039,GO:0046128,GO:0046483,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061598,GO:0061599,GO:0070566,GO:0071704,GO:0072521,GO:0090407,GO:1901068,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000401 410.0
PYH3_k127_6300096_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002951 387.0
PYH3_k127_6300096_8 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009926 307.0
PYH3_k127_6300096_9 Electron transfer flavoprotein K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001729 256.0
PYH3_k127_6318250_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000000000000000000000000000000000000000000000000006651 245.0
PYH3_k127_6318250_1 protein conserved in archaea - - - 0.0000000006687 70.0
PYH3_k127_6318250_2 PFAM 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000005097 53.0
PYH3_k127_6318250_3 Double zinc ribbon - - - 0.0006041 51.0
PYH3_k127_6318925_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007401 505.0
PYH3_k127_6318925_1 Type II/IV secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 439.0
PYH3_k127_6318925_10 PFAM TPR repeat-containing protein - - - 0.00000000000000000003962 107.0
PYH3_k127_6318925_11 PFAM Amino acid-binding ACT - - - 0.00000000000000001173 88.0
PYH3_k127_6318925_12 formylmethanofuran dehydrogenase, subunit E - - - 0.000000000000000434 81.0
PYH3_k127_6318925_2 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009457 293.0
PYH3_k127_6318925_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001434 302.0
PYH3_k127_6318925_4 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000288 247.0
PYH3_k127_6318925_5 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000003698 229.0
PYH3_k127_6318925_6 Protein of unknown function TPD sequence-motif - - - 0.000000000000000000000000000000000000000000000000000000002385 208.0
PYH3_k127_6318925_7 K homology RNA-binding domain K06961 - - 0.00000000000000000000000000000000000000000000000000000004025 201.0
PYH3_k127_6318925_8 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 - - 0.0000000000000000000000000000000000000000000000006201 184.0
PYH3_k127_6318925_9 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000001369 141.0
PYH3_k127_6350299_0 Oxidoreductase domain protein K18855 - 1.1.1.374 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001436 301.0
PYH3_k127_6350299_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.00000000000000000000000000000000000005544 149.0
PYH3_k127_6350299_2 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.000000000000000000000000000000004028 134.0
PYH3_k127_6382406_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 396.0
PYH3_k127_6382406_1 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001004 368.0
PYH3_k127_6382406_2 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002301 284.0
PYH3_k127_6382406_3 PFAM Phenazine biosynthesis PhzC PhzF protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000275 280.0
PYH3_k127_6382406_4 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000005285 171.0
PYH3_k127_6382406_5 nucleotide metabolic process - - - 0.000000000000000000000000000000000000005607 157.0
PYH3_k127_6382406_6 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000000000000549 76.0
PYH3_k127_6382406_7 membrane - - - 0.0000005346 59.0
PYH3_k127_6382406_8 - - - - 0.0002592 49.0
PYH3_k127_6445823_0 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000000000000000003251 188.0
PYH3_k127_6445823_1 ubiquitin-conjugating enzyme K10573 - 2.3.2.23 0.0000001023 62.0
PYH3_k127_6604957_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.25e-259 812.0
PYH3_k127_6604957_1 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 357.0
PYH3_k127_6604957_2 nitroreductase - - - 0.000000000000000000000000006658 111.0
PYH3_k127_6617452_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 1.117e-206 671.0
PYH3_k127_6617452_1 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 GO:0003674,GO:0003824,GO:0004018,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016840,GO:0016842,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046033,GO:0046390,GO:0046483,GO:0055086,GO:0070626,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 483.0
PYH3_k127_6617452_2 TIGRFAM iron-sulfur cluster binding protein K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000002182 222.0
PYH3_k127_6617452_3 Periplasmic copper-binding protein (NosD) - - - 0.0000000007928 71.0
PYH3_k127_663430_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 452.0
PYH3_k127_663430_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002554 386.0
PYH3_k127_663430_2 Protein of unknown function (DUF763) K09003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 383.0
PYH3_k127_663430_3 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000003296 239.0
PYH3_k127_663430_4 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000000000000000000000000000000000000000000000000000000002118 242.0
PYH3_k127_663430_5 RmlD substrate binding domain K01784,K02473,K03274,K08678 - 4.1.1.35,5.1.3.2,5.1.3.20,5.1.3.7 0.0000000000000000000000000000000000000000000000000000001711 200.0
PYH3_k127_663430_6 cellulase activity - - - 0.0000000000000000000000000000000000000000000000000001585 216.0
PYH3_k127_663430_7 Serine threonine phosphatase - - - 0.000000000000000001515 103.0
PYH3_k127_663430_8 Belongs to the glycosyl hydrolase 5 (cellulase A) family K19355 GO:0000272,GO:0003674,GO:0003824,GO:0004553,GO:0004567,GO:0005975,GO:0005976,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0010412,GO:0015923,GO:0016052,GO:0016787,GO:0016798,GO:0016985,GO:0016998,GO:0043170,GO:0044036,GO:0044237,GO:0044238,GO:0044247,GO:0044248,GO:0044260,GO:0044262,GO:0044264,GO:0044275,GO:0046355,GO:0071554,GO:0071704,GO:1901575 3.2.1.78 0.00000000000000000345 102.0
PYH3_k127_663430_9 serine threonine protein kinase K12132 - 2.7.11.1 0.0006012 50.0
PYH3_k127_6664590_0 SMART ATPase, AAA type, core K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 302.0
PYH3_k127_6664590_1 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000002158 167.0
PYH3_k127_6664590_2 ABC-2 family transporter protein K01992 - - 0.0000000000000005129 81.0
PYH3_k127_669219_0 synthetase (class II) K01880 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 383.0
PYH3_k127_669219_1 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002598 253.0
PYH3_k127_669219_2 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01485,K01487 - 3.5.4.1,3.5.4.3 0.000000000000000000000000000000000000000000000000002893 194.0
PYH3_k127_669219_3 Glutamine amidotransferase domain K01953 - 6.3.5.4 0.00000000000000000000000000000000000000000771 165.0
PYH3_k127_669219_4 Large-conductance mechanosensitive channel, MscL K03282 - - 0.00000000000000002874 87.0
PYH3_k127_6696163_0 TIGRFAM MIP family channel K02440,K06188 - - 0.00000000000000000000000000000000000000000000000000000000001178 213.0
PYH3_k127_6696163_1 ArsR transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000006941 202.0
PYH3_k127_6754223_0 PFAM Acetyl-CoA hydrolase transferase K18122 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 589.0
PYH3_k127_6754223_1 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002682 285.0
PYH3_k127_6754223_2 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.000000000000000000000000000000000000000000000000000000000004655 217.0
PYH3_k127_6754223_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000007068 179.0
PYH3_k127_6754223_4 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000002858 161.0
PYH3_k127_6754223_5 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.000000000000000000000000007291 110.0
PYH3_k127_6754223_6 - K00960 - 2.7.7.6 0.00000000000000000235 85.0
PYH3_k127_6754223_7 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.0000000000000001041 86.0
PYH3_k127_6754223_8 COG1404 Subtilisin-like serine proteases - - - 0.0000000000000002746 94.0
PYH3_k127_6765229_0 Aromatic amino acid lyase K01745 - 4.3.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007117 466.0
PYH3_k127_6765229_1 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004540,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0031123,GO:0034414,GO:0034470,GO:0034641,GO:0034660,GO:0042779,GO:0042780,GO:0042781,GO:0043170,GO:0043628,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1905267 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000258 299.0
PYH3_k127_6765229_2 Putative Flp pilus-assembly TadE/G-like - - - 0.0000000000000000000000000000000000000000000001085 196.0
PYH3_k127_6765229_3 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000001467 128.0
PYH3_k127_6765229_4 Transcriptional regulator, AbrB family - - - 0.000001503 55.0
PYH3_k127_6781436_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 513.0
PYH3_k127_6781436_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008476 439.0
PYH3_k127_6781436_2 toxin activity - - - 0.00005964 49.0
PYH3_k127_6792197_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.24e-322 1007.0
PYH3_k127_6792197_1 Acetyl-CoA acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000837 469.0
PYH3_k127_6792197_10 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000001662 159.0
PYH3_k127_6792197_11 Pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000002573 167.0
PYH3_k127_6792197_12 Methyltransferase type 11 - - - 0.000000000000000000000000000003106 128.0
PYH3_k127_6792197_13 Belongs to the enoyl-CoA hydratase isomerase family K00074,K15016,K15019,K15866 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0043956 1.1.1.157,1.1.1.35,4.2.1.116,4.2.1.17,5.3.3.18 0.000000000000001053 79.0
PYH3_k127_6792197_2 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 462.0
PYH3_k127_6792197_3 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004175 345.0
PYH3_k127_6792197_4 SMART Elongator protein 3 MiaB NifB K06935,K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009616 328.0
PYH3_k127_6792197_5 electron transfer flavoprotein, alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000546 303.0
PYH3_k127_6792197_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002909 277.0
PYH3_k127_6792197_7 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001588 248.0
PYH3_k127_6792197_8 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000008882 232.0
PYH3_k127_6792197_9 Isochorismatase family K09020 - 3.5.1.110 0.0000000000000000000000000000000000000000000000000002199 195.0
PYH3_k127_6900581_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004878 582.0
PYH3_k127_6900581_1 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000001388 205.0
PYH3_k127_6900581_2 Thiamine-binding protein - - - 0.0000000000000000000009058 98.0
PYH3_k127_6900581_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K06976 - - 0.00000003731 65.0
PYH3_k127_6918316_0 Pyridine nucleotide-disulphide oxidoreductase K07137 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 552.0
PYH3_k127_6941833_0 GTP-binding protein K06944 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 384.0
PYH3_k127_6941833_1 Belongs to the carbamate kinase family K00926 - 2.7.2.2 0.0000000000000000000000000000000000000000000000000000000003747 209.0
PYH3_k127_6941833_2 PFAM NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.000000000000000000009296 95.0
PYH3_k127_6955944_0 PFAM aminoacyl-tRNA synthetase class Ib K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 481.0
PYH3_k127_6955944_1 TIGRFAM drug resistance transporter, EmrB QacA subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000001314 225.0
PYH3_k127_6955944_2 ATPase (AAA superfamily K07133 - - 0.00000000000000000000000000000000000000000000000000000000000005797 230.0
PYH3_k127_6955944_3 nucleic acid binding OB-fold tRNA helicase-type K03698 - - 0.000000000000000000000000000000000000000000000000000000001084 216.0
PYH3_k127_6955944_4 domain protein - - - 0.0000000002306 66.0
PYH3_k127_6976983_0 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 349.0
PYH3_k127_6976983_1 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04564 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 301.0
PYH3_k127_6976983_2 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000138 268.0
PYH3_k127_6976983_3 PFAM zinc iron permease K16267 - - 0.0000000000000000000000000000000000000000000000000000000002097 212.0
PYH3_k127_6976983_4 Transcriptional regulator K07722 - - 0.0000000000000000000000000000000000000001795 154.0
PYH3_k127_6976983_5 membrane - - - 0.0000002049 61.0
PYH3_k127_7063952_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 617.0
PYH3_k127_7063952_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000001425 241.0
PYH3_k127_7085536_0 PFAM NAD dependent epimerase dehydratase family K00091 - 1.1.1.219 0.00000000000000000000000000000000000000000000000000000003687 208.0
PYH3_k127_7222974_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 480.0
PYH3_k127_7222974_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 431.0
PYH3_k127_7222974_10 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.000000000000000001765 88.0
PYH3_k127_7222974_11 - - - - 0.00000000000000002173 82.0
PYH3_k127_7222974_12 Domain of unknown function DUF11 - - - 0.00000000000004201 87.0
PYH3_k127_7222974_13 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000008677 83.0
PYH3_k127_7222974_14 PKD domain K01183 - 3.2.1.14 0.0000000001041 75.0
PYH3_k127_7222974_15 - - - - 0.00000007905 63.0
PYH3_k127_7222974_2 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 309.0
PYH3_k127_7222974_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 293.0
PYH3_k127_7222974_4 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000003105 152.0
PYH3_k127_7222974_5 amine dehydrogenase activity K20276 - - 0.00000000000000000000000000000000001887 156.0
PYH3_k127_7222974_6 RNA polymerase subunit 9 K03057 - - 0.000000000000000000000000001099 120.0
PYH3_k127_7222974_7 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000005867 109.0
PYH3_k127_7222974_8 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000001444 117.0
PYH3_k127_7222974_9 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000003891 97.0
PYH3_k127_7240733_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 1.343e-239 754.0
PYH3_k127_7240733_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 608.0
PYH3_k127_7240733_10 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000000000000000003231 224.0
PYH3_k127_7240733_11 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000032 184.0
PYH3_k127_7240733_12 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000001093 159.0
PYH3_k127_7240733_13 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.0000000000000000000000000000000000000001313 156.0
PYH3_k127_7240733_14 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000008856 124.0
PYH3_k127_7240733_15 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000000000000000000001854 131.0
PYH3_k127_7240733_16 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.00000000000000000000341 94.0
PYH3_k127_7240733_17 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000001452 108.0
PYH3_k127_7240733_18 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000002329 60.0
PYH3_k127_7240733_2 Protein of unknown function (DUF521) K09123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 465.0
PYH3_k127_7240733_3 Dehydrogenase K00248,K11410,K18244 GO:0000062,GO:0000166,GO:0003674,GO:0003824,GO:0003995,GO:0004085,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005740,GO:0005759,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009605,GO:0009719,GO:0009725,GO:0009987,GO:0009991,GO:0010033,GO:0014070,GO:0016020,GO:0016042,GO:0016043,GO:0016054,GO:0016491,GO:0016627,GO:0017076,GO:0019395,GO:0019605,GO:0019626,GO:0019752,GO:0022607,GO:0030258,GO:0030554,GO:0031090,GO:0031667,GO:0031960,GO:0031966,GO:0031967,GO:0031974,GO:0031975,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0033218,GO:0033539,GO:0033993,GO:0034440,GO:0036094,GO:0042221,GO:0042594,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046359,GO:0046395,GO:0046459,GO:0048037,GO:0048545,GO:0050660,GO:0050662,GO:0050896,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0051384,GO:0052890,GO:0055114,GO:0065003,GO:0070013,GO:0071704,GO:0071840,GO:0072329,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901567,GO:1901575,GO:1901681 1.3.8.1,1.3.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 456.0
PYH3_k127_7240733_4 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 395.0
PYH3_k127_7240733_5 UvrD REP helicase K03657,K07465 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001565 373.0
PYH3_k127_7240733_6 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006723 305.0
PYH3_k127_7240733_7 GTPase activity K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 289.0
PYH3_k127_7240733_8 mevalonate kinase activity K00869,K15633 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0005829,GO:0006066,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006694,GO:0006695,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008203,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016126,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901362,GO:1901564,GO:1901576,GO:1901615,GO:1901617,GO:1902652,GO:1902653 2.7.1.36,5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000008841 243.0
PYH3_k127_7240733_9 Belongs to the metallo-dependent hydrolases superfamily. HutI family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000000000000000111 236.0
PYH3_k127_7259331_0 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002798 441.0
PYH3_k127_7259331_1 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 338.0
PYH3_k127_7259331_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003178 325.0
PYH3_k127_7259331_3 PFAM phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 317.0
PYH3_k127_7259331_4 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000007489 158.0
PYH3_k127_7276632_0 helicase superfamily c-terminal domain K03724 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007743 531.0
PYH3_k127_7276632_1 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 424.0
PYH3_k127_7276632_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000006435 126.0
PYH3_k127_7425013_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 1e-234 744.0
PYH3_k127_7425013_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 512.0
PYH3_k127_7425013_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002074 423.0
PYH3_k127_7425013_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 323.0
PYH3_k127_7425013_4 Protein of unknown function DUF89 K09116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007799 264.0
PYH3_k127_7425013_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000002106 231.0
PYH3_k127_7425013_6 TIGRFAM 2-oxoacid acceptor oxidoreductase, delta subunit, pyruvate 2-ketoisovalerate K00171,K00172 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000009192 206.0
PYH3_k127_7425013_7 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.000000000000000000000000000000000003531 141.0
PYH3_k127_7425013_8 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - GO:0000394,GO:0003674,GO:0005488,GO:0005509,GO:0006139,GO:0006388,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008380,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0071704,GO:0090304,GO:1901360 - 0.000000000000000000000000021 113.0
PYH3_k127_7425013_9 PFAM peptidase M6, immune inhibitor A - - - 0.000000000000000000002039 110.0
PYH3_k127_7432418_0 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000007737 246.0
PYH3_k127_7432418_1 Involved in pre-rRNA and tRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'-hydroxyl methylation of ribose moieties in rRNA and tRNA. Site specificity is provided by a guide RNA that base pairs with the substrate. Methylation occurs at a characteristic distance from the sequence involved in base pairing with the guide RNA K04795 - - 0.0000000000000000000000000000000000000000000000000000000002171 209.0
PYH3_k127_7432418_2 ribosomal protein S15 K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000002686 153.0
PYH3_k127_7432418_3 PFAM Tetratricopeptide repeat - - - 0.000000000002113 72.0
PYH3_k127_7488444_0 to orf3 of fosmid clone 4B7mr3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001019 267.0
PYH3_k127_7488444_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000797 197.0
PYH3_k127_7488444_2 Protein of unknown function (DUF1616) - - - 0.000000000000000000000000000000000000000000000002587 184.0
PYH3_k127_7488444_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000008568 166.0
PYH3_k127_7488444_4 ABC-type antimicrobial peptide transport system, permease component - - - 0.0000000000000001875 92.0
PYH3_k127_7488444_5 - - - - 0.0000000000000009525 91.0
PYH3_k127_7488444_6 Efflux ABC transporter, permease protein K02004 - - 0.00000007356 64.0
PYH3_k127_7488444_7 MacB-like periplasmic core domain K02004 - - 0.00002405 56.0
PYH3_k127_7501489_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 441.0
PYH3_k127_7501489_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 415.0
PYH3_k127_7501489_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K17870 - 1.6.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000339 281.0
PYH3_k127_7501489_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.000000000000000000000000000000000000000000000000000000006481 218.0
PYH3_k127_7501489_4 6-O-methylguanine DNA methyltransferase, DNA binding domain K05982 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.21.7 0.00000000000009718 77.0
PYH3_k127_7501489_5 SCP-2 sterol transfer family - - - 0.0000000000007934 72.0
PYH3_k127_7501489_6 Thermophilic metalloprotease (M29) - - - 0.000000000003918 78.0
PYH3_k127_7501489_7 - - - - 0.0000000009831 69.0
PYH3_k127_7501489_8 virion core protein (lumpy skin disease virus) - - - 0.00000074 61.0
PYH3_k127_7501489_9 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03537 - 3.1.26.5 0.0009424 46.0
PYH3_k127_7526848_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000003138 156.0
PYH3_k127_7526848_1 Toxic component of a toxin-antitoxin (TA) module. An RNase K07065 - - 0.00000000000000000000000000005412 122.0
PYH3_k127_7526848_2 SpoVT / AbrB like domain - - - 0.0000000000005019 72.0
PYH3_k127_7526848_3 Predicted membrane protein (DUF2318) - - - 0.000005466 49.0
PYH3_k127_7551087_0 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005505 270.0
PYH3_k127_7551087_1 Radical SAM superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006151 268.0
PYH3_k127_7551087_10 Acetyltransferase (GNAT) domain - - - 0.00000000003329 74.0
PYH3_k127_7551087_2 TatD related DNase K07049 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001086 266.0
PYH3_k127_7551087_3 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002106 176.0
PYH3_k127_7551087_4 pre-rRNA processing protein involved in ribosome biogenesis K09140 - - 0.0000000000000000000000000000000001049 147.0
PYH3_k127_7551087_5 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000348 133.0
PYH3_k127_7551087_6 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.00000000000000000000000005533 121.0
PYH3_k127_7551087_7 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0000000000000000000003698 96.0
PYH3_k127_7551087_8 Trm112p-like protein - - - 0.000000000000000000001417 95.0
PYH3_k127_7551087_9 RDD family - - - 0.00000000000000006845 88.0
PYH3_k127_7597680_0 SMART Elongator protein 3 MiaB NifB K04034 - 1.21.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 510.0
PYH3_k127_7597680_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000021 380.0
PYH3_k127_7597680_2 domain protein - - - 0.000000000000001757 88.0
PYH3_k127_7608052_0 Carbamoyl-phosphate synthetase ammonia chain K01955 - 6.3.5.5 0.0 1610.0
PYH3_k127_7608052_1 Belongs to the CarA family K01955,K01956 GO:0000050,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005951,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0019627,GO:0019752,GO:0032991,GO:0034641,GO:0040007,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494 6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004911 528.0
PYH3_k127_7608052_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr) K01868 GO:0002161,GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009436 440.0
PYH3_k127_7608052_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 356.0
PYH3_k127_7608052_4 Fibronectin type 3 domain K12685,K16785,K16786,K16787 - - 0.0000000000000000000000000000000000000000000000000000000000009847 239.0
PYH3_k127_7608052_5 protein conserved in archaea - - - 0.0000000000000000002521 102.0
PYH3_k127_7608052_6 - - - - 0.00000000000000001001 97.0
PYH3_k127_7608052_7 Ribbon-helix-helix protein, copG family K07722 - - 0.00000000000000001962 90.0
PYH3_k127_7608052_8 Membrane - - - 0.0000000000000053 85.0
PYH3_k127_7608052_9 Protein of unknown function (DUF1349) - - - 0.00000002124 68.0
PYH3_k127_7736024_0 ABC transporter K02193 - 3.6.3.41 0.0000000000000000000000000000000000000000000000000000007587 198.0
PYH3_k127_7736024_1 Cytochrome C assembly protein K02195 GO:0001539,GO:0002048,GO:0002049,GO:0003674,GO:0003824,GO:0004096,GO:0004601,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006518,GO:0006629,GO:0006643,GO:0006664,GO:0006807,GO:0006810,GO:0006928,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009237,GO:0009247,GO:0009636,GO:0009987,GO:0015886,GO:0016020,GO:0016021,GO:0016209,GO:0016491,GO:0016684,GO:0019184,GO:0019290,GO:0019748,GO:0031224,GO:0031226,GO:0034641,GO:0040011,GO:0042221,GO:0043043,GO:0043107,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044425,GO:0044459,GO:0044464,GO:0044550,GO:0046467,GO:0048870,GO:0050896,GO:0051179,GO:0051181,GO:0051186,GO:0051188,GO:0051234,GO:0051674,GO:0051716,GO:0055114,GO:0070887,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0071973,GO:0071975,GO:0071977,GO:0071978,GO:0097237,GO:0097588,GO:0098754,GO:0098869,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576,GO:1901678,GO:1903509,GO:1990748 - 0.0000000000000000000000000000000000000000000005985 186.0
PYH3_k127_7736024_2 CcmB protein K02194 - - 0.0000000000000000000000000000000000004194 153.0
PYH3_k127_7740415_0 CoA binding domain K09181 - - 8.798e-274 865.0
PYH3_k127_7740415_1 PFAM AMP-dependent synthetase and ligase - - - 2.634e-221 699.0
PYH3_k127_7740415_2 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 606.0
PYH3_k127_7740415_3 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002081 276.0
PYH3_k127_7740415_4 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001294 260.0
PYH3_k127_7740415_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000005227 252.0
PYH3_k127_7740415_6 - - - - 0.00000000000000000001034 99.0
PYH3_k127_7740415_7 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00196 - - 0.00000000000000000002015 94.0
PYH3_k127_7740415_8 Molybdopterin converting factor, small subunit K03636,K03750,K07101 GO:0003674,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0019538,GO:0031386,GO:0032446,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0070647,GO:0071704,GO:1901564 2.10.1.1 0.00000000004425 67.0
PYH3_k127_7763939_0 D-aminoacyl-tRNA deacylase with broad substrate specificity. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo K09716 - 3.1.1.96 0.0000000000000000000000000000000000000000000000000000000000000000000000000002011 265.0
PYH3_k127_7763939_1 COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain K07557 - 2.6.1.97 0.000000000000000000000000000000000000000001977 169.0
PYH3_k127_7763939_2 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000000000000001378 109.0
PYH3_k127_7763939_3 Putative zinc ribbon domain - - - 0.0000000000000000004806 89.0
PYH3_k127_7789878_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 422.0
PYH3_k127_7789878_1 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000002685 59.0
PYH3_k127_7802511_0 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000171 254.0
PYH3_k127_7802511_1 Domain of unknown function DUF11 - - - 0.000000001062 73.0
PYH3_k127_7829399_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 6.574e-207 663.0
PYH3_k127_7829399_1 SPFH domain-Band 7 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 454.0
PYH3_k127_7829399_2 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002795 263.0
PYH3_k127_7829399_3 - - - - 0.00000000000000000000000000000000000006387 148.0
PYH3_k127_7829399_4 phytanoyl-CoA dioxygenase - - - 0.0000000000000000000000000004366 131.0
PYH3_k127_7829399_5 Fibronectin type III domain protein - - - 0.0000000000000000000005516 112.0
PYH3_k127_7848963_0 PFAM ATP-dependent carboxylate-amine ligase domain protein, ATP-grasp K05827 - 6.3.2.43 0.00000000000000000000000000000000000000000000000000000000000007817 219.0
PYH3_k127_7848963_1 ferredoxin oxidoreductase, subunit alpha K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000001467 176.0
PYH3_k127_7848963_2 COG1522 Transcriptional regulators - - - 0.0000000000000000000000000000685 121.0
PYH3_k127_7848963_3 4Fe-4S dicluster domain K00176 - 1.2.7.3 0.000000000000000004005 86.0
PYH3_k127_7848963_4 TIGRFAM lysine biosynthesis protein LysW K05826 - - 0.00000000000009344 72.0
PYH3_k127_7884648_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002627 550.0
PYH3_k127_7884648_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 2 subfamily K01889 GO:0003674,GO:0003824,GO:0004812,GO:0004826,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007953 428.0
PYH3_k127_7884648_10 Ribosomal protein S1-like RNA-binding domain K07463 - - 0.00003529 49.0
PYH3_k127_7884648_2 Cysteinyl-tRNA synthetase K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000147 332.0
PYH3_k127_7884648_3 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004312 267.0
PYH3_k127_7884648_4 Belongs to the UPF0215 family K09120 - - 0.0000000000000000000000000000000000000000000003984 174.0
PYH3_k127_7884648_5 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.0000000000000000000000000000000000001641 145.0
PYH3_k127_7884648_6 Peptidyl-tRNA hydrolase PTH2 K04794 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.1.1.29 0.000000000000000000000000000000001721 132.0
PYH3_k127_7884648_7 Protein of unknown function (DUF1616) - - - 0.000000000000000000001114 102.0
PYH3_k127_7884648_8 tetratricopeptide repeat - - - 0.000000005042 64.0
PYH3_k127_7884648_9 - - - - 0.0000001598 59.0
PYH3_k127_7897209_0 acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 453.0
PYH3_k127_7897209_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K03239,K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 402.0
PYH3_k127_7897209_10 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000000000000000000000000000000000000000002611 164.0
PYH3_k127_7897209_11 PIN domain of ribonuclease K07060 - - 0.0000000000000000000000000000329 128.0
PYH3_k127_7897209_12 - - - - 0.000000000000000000000000513 109.0
PYH3_k127_7897209_13 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.0000000000000002298 94.0
PYH3_k127_7897209_14 - - - - 0.0000000000001447 75.0
PYH3_k127_7897209_15 BNR repeat-containing family member - - - 0.000000003509 71.0
PYH3_k127_7897209_16 alginic acid biosynthetic process - - - 0.000000004963 71.0
PYH3_k127_7897209_17 - K21029 - 2.7.7.80 0.00000007156 57.0
PYH3_k127_7897209_2 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005013 409.0
PYH3_k127_7897209_3 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 368.0
PYH3_k127_7897209_4 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 343.0
PYH3_k127_7897209_5 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 316.0
PYH3_k127_7897209_6 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001798 282.0
PYH3_k127_7897209_7 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000006424 252.0
PYH3_k127_7897209_8 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000000000000000001436 224.0
PYH3_k127_7897209_9 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.0000000000000000000000000000000000000000000000007205 182.0
PYH3_k127_8038092_0 Aminotransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 309.0
PYH3_k127_8038092_1 COG2998 ABC-type tungstate transport system, permease component - - - 0.000000000000000000000000000000000000000000000000000000000002982 218.0
PYH3_k127_8038092_2 PFAM binding-protein-dependent transport systems inner membrane component K05773 - - 0.000000000000000000000000000000000000000000000000000462 191.0
PYH3_k127_8038092_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K06857 - 3.6.3.55 0.000000000000000000000000000000000000000000000000002263 192.0
PYH3_k127_8038092_4 Belongs to the UPF0216 family K09737 - - 0.000000177 58.0
PYH3_k127_8066645_0 KH domain K07041 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006319 394.0
PYH3_k127_8066645_1 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002166 259.0
PYH3_k127_8066645_2 PFAM sodium hydrogen exchanger - - - 0.000000000000000000000000000000000000000000000000000000000000000009795 239.0
PYH3_k127_8099032_0 Phytoene dehydrogenase K15745 - 1.3.99.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 452.0
PYH3_k127_8099032_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000004978 175.0
PYH3_k127_8099032_2 Transcriptional regulator K03524 - 6.3.4.15 0.0000000000000000000000003069 110.0
PYH3_k127_8099032_3 PFAM Squalene phytoene synthase - - - 0.00008059 54.0
PYH3_k127_8121645_0 Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs K07254 - 2.1.1.206 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002286 361.0
PYH3_k127_8121645_1 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000004121 259.0
PYH3_k127_8148129_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 1.314e-266 835.0
PYH3_k127_8148129_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001431 382.0
PYH3_k127_8148129_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004793 302.0
PYH3_k127_8148129_3 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000000000000000000000000000000000000003241 238.0
PYH3_k127_8148129_4 Cytidylyltransferase-like K00952 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.7.1 0.0000000000000000000000000000000000000000000001654 173.0
PYH3_k127_8148129_5 Asparaginase K01424,K13051 - 3.4.19.5,3.5.1.1 0.00000000000000000000000000000003434 130.0
PYH3_k127_8152825_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.098e-236 743.0
PYH3_k127_8152825_1 TIGRFAM oxaloacetate decarboxylase alpha subunit K01960 - 6.4.1.1 1.622e-195 630.0
PYH3_k127_8152825_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 402.0
PYH3_k127_8152825_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 362.0
PYH3_k127_8152825_4 Domain of unknown function (DUF2088) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001284 249.0
PYH3_k127_8152825_5 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a repressor K03524 - 6.3.4.15 0.000000000000000000000000000000000000000008112 164.0
PYH3_k127_8152825_6 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000006815 138.0
PYH3_k127_8152825_7 Cytotoxic translational repressor of toxin-antitoxin stability system K06218 - - 0.000000000000000000000005104 103.0
PYH3_k127_8152825_8 - - - - 0.000000000000000002917 86.0
PYH3_k127_8171134_0 PD-(D/E)XK nuclease superfamily K03657 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007043 411.0
PYH3_k127_8171134_1 - - - - 0.00000000000000000000000000000395 133.0
PYH3_k127_8171134_2 PFAM Ribonuclease III - - - 0.00000000000000000000000004887 116.0
PYH3_k127_8171134_3 protein N-acetylglucosaminyltransferase activity K12600 - - 0.00000001085 64.0
PYH3_k127_8171134_4 Protein of unknown function (DUF559) - - - 0.000002556 55.0
PYH3_k127_8184868_0 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00186 - 1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 435.0
PYH3_k127_8184868_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 403.0
PYH3_k127_8184868_2 PFAM Radical SAM domain protein K22227 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 364.0
PYH3_k127_8184868_3 Nitroreductase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 344.0
PYH3_k127_8184868_4 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 332.0
PYH3_k127_8184868_5 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000006304 236.0
PYH3_k127_8184868_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000003019 216.0
PYH3_k127_8184868_8 4Fe-4S dicluster domain K00188 - 1.2.7.7 0.000000000000000000000004297 104.0
PYH3_k127_8184868_9 methyltransferase - - - 0.000000000000000009632 94.0
PYH3_k127_8214896_0 Enoyl-CoA hydratase/isomerase - - - 3.226e-198 638.0
PYH3_k127_8214896_1 Enoyl-CoA hydratase isomerase K07539 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009117,GO:0009150,GO:0009154,GO:0009166,GO:0009259,GO:0009261,GO:0009987,GO:0016787,GO:0016822,GO:0016823,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0033865,GO:0033869,GO:0033875,GO:0034031,GO:0034032,GO:0034034,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044273,GO:0044281,GO:0044283,GO:0046434,GO:0046483,GO:0046700,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901787,GO:1901788 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002282 589.0
PYH3_k127_8214896_10 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.257 0.0000001654 61.0
PYH3_k127_8214896_11 Calcineurin-like phosphoesterase - - - 0.000007178 59.0
PYH3_k127_8214896_2 Belongs to the thiolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004813 456.0
PYH3_k127_8214896_3 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003532 371.0
PYH3_k127_8214896_4 radical SAM domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008246 352.0
PYH3_k127_8214896_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005961 277.0
PYH3_k127_8214896_6 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000007584 273.0
PYH3_k127_8214896_7 PFAM PKD domain containing protein - - - 0.00000000000000000000000000000000002536 156.0
PYH3_k127_8214896_8 S-(hydroxymethyl)glutathione dehydrogenase activity - - - 0.00000000000000000000000000000000004363 149.0
PYH3_k127_8214896_9 Putative small multi-drug export protein - - - 0.000000000000000004069 93.0
PYH3_k127_821863_0 cog cog1373 K07133 - - 0.00000000000000000000000000000000000000001561 169.0
PYH3_k127_821863_1 HhH-GPD family K07457 - - 0.0000000000000000007119 88.0
PYH3_k127_8228498_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600,K00605,K18847 GO:0001505,GO:0003674,GO:0003824,GO:0004047,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005960,GO:0006082,GO:0006520,GO:0006544,GO:0006546,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008483,GO:0009056,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016054,GO:0016740,GO:0016741,GO:0016769,GO:0017144,GO:0019464,GO:0019752,GO:0032259,GO:0032991,GO:0042133,GO:0042135,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606,GO:1902494,GO:1990204 2.1.2.1,2.1.2.10,2.2.1.8 3.121e-295 955.0
PYH3_k127_8228498_1 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 8.958e-279 934.0
PYH3_k127_8228498_10 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000001583 259.0
PYH3_k127_8228498_11 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004105 259.0
PYH3_k127_8228498_12 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008057 283.0
PYH3_k127_8228498_14 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003486 253.0
PYH3_k127_8228498_15 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000009433 243.0
PYH3_k127_8228498_16 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000001954 244.0
PYH3_k127_8228498_17 Peptidase dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001114 235.0
PYH3_k127_8228498_18 PFAM Cobyrinic acid ac-diamide synthase K07321 - - 0.00000000000000000000000000000000000000000000000000000000000002218 226.0
PYH3_k127_8228498_19 Roadblock LC7 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000428 219.0
PYH3_k127_8228498_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 2.369e-239 760.0
PYH3_k127_8228498_20 TIGRFAM bifunctional phosphoglucose phosphomannose isomerase K15916 - 5.3.1.8,5.3.1.9 0.000000000000000000000000000000000000000000000000000000001377 213.0
PYH3_k127_8228498_22 DNA polymerase alpha chain like domain - - - 0.00000000000000000000000000000000000000000000000008978 184.0
PYH3_k127_8228498_23 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.00000000000000000000000000000000000000000000001013 175.0
PYH3_k127_8228498_24 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000002105 174.0
PYH3_k127_8228498_25 RNA-binding protein of the translin family K07477 - - 0.0000000000000000000000000000000000000002763 157.0
PYH3_k127_8228498_26 4Fe-4S binding domain - - - 0.00000000000000000000000000000000007783 149.0
PYH3_k127_8228498_27 PFAM CBS domain containing protein - - - 0.000000000000000000000000009787 117.0
PYH3_k127_8228498_28 BFD-like [2Fe-2S] binding domain - - - 0.000000000000000000000004297 104.0
PYH3_k127_8228498_29 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.000000000000000000005151 100.0
PYH3_k127_8228498_3 2Fe-2S iron-sulfur cluster binding domain K00302 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009516 608.0
PYH3_k127_8228498_30 - - - - 0.000000000000000001214 89.0
PYH3_k127_8228498_31 CARDB - - - 0.0000000000000001597 93.0
PYH3_k127_8228498_32 PFAM 4-vinyl reductase, 4VR K07013 - - 0.000000000000009838 84.0
PYH3_k127_8228498_34 Serine threonine protein kinase - - - 0.0000000002613 73.0
PYH3_k127_8228498_35 Roadblock LC7 family protein K07131 - - 0.000000001653 64.0
PYH3_k127_8228498_36 PIN domain - - - 0.0000005596 56.0
PYH3_k127_8228498_37 protein conserved in archaea - - - 0.0002902 51.0
PYH3_k127_8228498_38 Nucleic acid binding - - - 0.0003012 51.0
PYH3_k127_8228498_4 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 531.0
PYH3_k127_8228498_5 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 455.0
PYH3_k127_8228498_6 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 426.0
PYH3_k127_8228498_7 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005004 366.0
PYH3_k127_8228498_8 Sarcosine oxidase K00303 - 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 348.0
PYH3_k127_8228498_9 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 321.0
PYH3_k127_8252623_0 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 GO:0003674,GO:0003824,GO:0004719,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006464,GO:0006479,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008213,GO:0008276,GO:0008757,GO:0009987,GO:0010340,GO:0016740,GO:0016741,GO:0019538,GO:0032259,GO:0036211,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044464,GO:0051998,GO:0071704,GO:0140096,GO:1901564 2.1.1.77 0.000000000000000000000000000000000000000000000000000001119 199.0
PYH3_k127_8252623_1 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000001115 169.0
PYH3_k127_8252623_2 GvpD gas vesicle protein - - - 0.000000000000000000000000000000000000000009321 164.0
PYH3_k127_8252623_3 Tetratricopeptide TPR_2 repeat protein - - - 0.0000001604 65.0
PYH3_k127_8252623_4 RecA-superfamily ATPases implicated in signal transduction K08482 - - 0.0004734 54.0
PYH3_k127_8475124_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001874 546.0
PYH3_k127_8475124_1 Archaeal transcriptional regulator TrmB - - - 0.0000000000000000000000000000000000000000000000000000000000000000001024 238.0
PYH3_k127_8475124_2 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000002666 90.0
PYH3_k127_8475124_3 Ribosomal protein L37e K02922 - - 0.00000000000000001188 83.0
PYH3_k127_8475124_4 Ribosomal protein L37e K02922 - - 0.0000000000000001509 80.0
PYH3_k127_8475124_5 Protein of unknown function (DUF835) - - - 0.00000000005237 76.0
PYH3_k127_8524790_0 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 375.0
PYH3_k127_8524790_1 PFAM Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008951 267.0
PYH3_k127_8524790_2 PFAM TPR repeat-containing protein - - - 0.000000000000000000000000000000000000000000000000000003143 220.0
PYH3_k127_8524790_3 - - - - 0.0000000000000000000000000000000000002939 161.0
PYH3_k127_8524790_4 COG0457 FOG TPR repeat - - - 0.00000000000003374 88.0
PYH3_k127_8537905_0 Citrate transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 437.0
PYH3_k127_8537905_1 ATPase, AAA superfamily K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 412.0
PYH3_k127_8537905_2 Fibronectin type III domain - - - 0.0000000000000000000000000000000000000000000000000000003276 204.0
PYH3_k127_8537905_3 DNA replication proofreading K02336,K06877 - 2.7.7.7 0.00000009611 60.0
PYH3_k127_8599701_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1075.0
PYH3_k127_8646090_0 4fe-4S ferredoxin, iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 7.108e-286 896.0
PYH3_k127_8646090_1 PFAM Radical SAM domain protein K22226 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 516.0
PYH3_k127_8646090_10 to GP 1890198 percent identity - - - 0.000000000000000000000000000000000000000000000000000000000000000008905 235.0
PYH3_k127_8646090_11 Cytochrome C assembly protein K02198 - - 0.000000000000000000000000000000000000000000000000000002515 218.0
PYH3_k127_8646090_12 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000000000000000000000004899 198.0
PYH3_k127_8646090_13 SMART regulatory protein AsnC Lrp family K22225 - - 0.000000000000000000000000000000000000000000000106 172.0
PYH3_k127_8646090_14 Uroporphyrinogen-III synthase HemD K01719 - 4.2.1.75 0.0000000000000000000000000000000000000000000002247 179.0
PYH3_k127_8646090_15 SMART Transcription regulator, AsnC-type - - - 0.0000000000000000000000000000000000003117 147.0
PYH3_k127_8646090_16 TIGRFAM siroheme synthase K02304 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0016628,GO:0018130,GO:0019354,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043115,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0051186,GO:0051188,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,4.99.1.4 0.000000000000000000000000000000000005978 145.0
PYH3_k127_8646090_17 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000004381 100.0
PYH3_k127_8646090_18 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000319 102.0
PYH3_k127_8646090_19 pfam abc K01990,K09695 - - 0.000000000000001028 83.0
PYH3_k127_8646090_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 505.0
PYH3_k127_8646090_21 transcriptional - - - 0.000000000008665 76.0
PYH3_k127_8646090_22 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides - - - 0.00000000156 69.0
PYH3_k127_8646090_24 helix_turn_helix ASNC type K03719 - - 0.00000003913 65.0
PYH3_k127_8646090_25 helix_turn_helix ASNC type K03719 - - 0.000000575 61.0
PYH3_k127_8646090_26 - - - - 0.000043 53.0
PYH3_k127_8646090_3 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006078 435.0
PYH3_k127_8646090_4 Belongs to the ALAD family K01698 - 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 402.0
PYH3_k127_8646090_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003298 323.0
PYH3_k127_8646090_6 heterodisulfide reductase K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001049 277.0
PYH3_k127_8646090_7 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000378 248.0
PYH3_k127_8646090_8 UbiA prenyltransferase family K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000007541 242.0
PYH3_k127_8646090_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.000000000000000000000000000000000000000000000000000000000000000008486 239.0
PYH3_k127_8665518_0 CO dehydrogenase/acetyl-CoA synthase complex beta subunit - - - 3.668e-241 794.0
PYH3_k127_8665518_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 7.448e-205 687.0
PYH3_k127_8665518_10 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336,K05299 - 1.17.1.10,1.6.5.3 0.00000000000000000000000000000000000008221 143.0
PYH3_k127_8665518_11 Domain of unknown function (DUF3786) - - - 0.000000000000000000000000000000005361 135.0
PYH3_k127_8665518_12 4Fe-4S dicluster domain - - - 0.000000000000000000000000000002555 124.0
PYH3_k127_8665518_13 Predicted RNA-binding protein - - - 0.0000171 48.0
PYH3_k127_8665518_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00197 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 419.0
PYH3_k127_8665518_3 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006315 355.0
PYH3_k127_8665518_4 CO dehydrogenase acetyl-CoA synthase K00194 - 2.1.1.245 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 298.0
PYH3_k127_8665518_5 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000001072 248.0
PYH3_k127_8665518_6 DNA repair and recombination protein RadB K04484 GO:0000150,GO:0000217,GO:0000400,GO:0000724,GO:0000725,GO:0000730,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003697,GO:0003824,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006302,GO:0006310,GO:0006312,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009314,GO:0009628,GO:0009987,GO:0010212,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0022607,GO:0033554,GO:0034622,GO:0034641,GO:0042148,GO:0042623,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0045003,GO:0046483,GO:0050896,GO:0051716,GO:0065003,GO:0065004,GO:0071704,GO:0071824,GO:0071840,GO:0090304,GO:0090735,GO:0097159,GO:0140097,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000001286 207.0
PYH3_k127_8665518_7 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123,K05299 - 1.17.1.10,1.17.1.9 0.000000000000000000000000000000000000000000000000000000002609 203.0
PYH3_k127_8665518_8 PFAM Cobyrinic acid a,c-diamide synthase K07321 - - 0.0000000000000000000000000000000000000000000000009991 183.0
PYH3_k127_8665518_9 Catalyzes the formation of isopentenyl diphosphate (IPP), the building block of all isoprenoids K06981 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006629,GO:0006720,GO:0006721,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016114,GO:0016740,GO:0016772,GO:0016776,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0102043,GO:1901576 2.7.4.26 0.000000000000000000000000000000000000000000001104 176.0
PYH3_k127_8673053_0 LamG domain protein jellyroll fold domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 330.0
PYH3_k127_8673053_1 Required for chromosome condensation and partitioning K03529 - - 0.000000000000000000000000000000000000000000000000000000000000000000114 244.0
PYH3_k127_8673053_2 chromosome segregation and condensation protein ScpA K05896 - - 0.0000000000000000000000000000000000000000000003155 178.0
PYH3_k127_8673053_3 TIGRFAM segregation and condensation protein B K06024 - - 0.00000000000000000000000000000001057 134.0
PYH3_k127_8673053_4 PFAM PKD domain containing protein - - - 0.000000000000000000000003758 121.0
PYH3_k127_8673053_5 Parallel beta-helix repeats - - - 0.00000000002255 79.0
PYH3_k127_8673053_6 - - - - 0.000000418 53.0
PYH3_k127_8673053_7 PKD domain K01176,K01179,K02395,K21429 - 3.2.1.1,3.2.1.4 0.000007289 61.0
PYH3_k127_868468_0 Involved in molybdopterin and thiamine biosynthesis, family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000001485 175.0
PYH3_k127_868468_1 DnaB-like helicase C terminal domain - - - 0.0000000000000000000000000000000000048 145.0
PYH3_k127_868468_2 transferase activity, transferring glycosyl groups - - - 0.000008448 53.0
PYH3_k127_868468_3 Tetratricopeptide repeat - - - 0.00005484 55.0
PYH3_k127_8753125_0 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 452.0
PYH3_k127_8753125_1 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000000000000000000007482 128.0
PYH3_k127_8753125_2 DNA polymerase type-B family K02319 - 2.7.7.7 0.0000000000000000000003584 100.0
PYH3_k127_8793113_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 604.0
PYH3_k127_8793113_1 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.000000000000000000000000000000000000000000000000000000000003006 214.0
PYH3_k127_8793113_2 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000007014 200.0
PYH3_k127_8793113_3 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000000002464 147.0
PYH3_k127_8831133_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 1.741e-217 688.0
PYH3_k127_8831133_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 291.0
PYH3_k127_8831133_10 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001004 147.0
PYH3_k127_8831133_11 Translation initiation factor SUI1 K03113 GO:0001731,GO:0002181,GO:0002183,GO:0002188,GO:0002190,GO:0002192,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0065003,GO:0070992,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0110017,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000001817 149.0
PYH3_k127_8831133_12 Belongs to the eukaryotic ribosomal protein eL32 family K02912 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000263 139.0
PYH3_k127_8831133_13 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000001588 128.0
PYH3_k127_8831133_14 ribosomal protein L24 K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000573 108.0
PYH3_k127_8831133_15 Belongs to the ATCase OTCase family K00611 - 2.1.3.3 0.000000000000000000008725 91.0
PYH3_k127_8831133_16 ribosomal protein S14 K02954 - - 0.0000000000000003341 87.0
PYH3_k127_8831133_17 Ribosomal L29 protein K02904 - - 0.00000000000006174 79.0
PYH3_k127_8831133_18 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 - 3.1.26.5 0.00000000000007092 79.0
PYH3_k127_8831133_2 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000007939 242.0
PYH3_k127_8831133_3 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000004317 212.0
PYH3_k127_8831133_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000001357 205.0
PYH3_k127_8831133_5 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000001958 199.0
PYH3_k127_8831133_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000004288 188.0
PYH3_k127_8831133_7 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000283 179.0
PYH3_k127_8831133_8 TIGRFAM ribosomal protein L30P K02907 - - 0.000000000000000000000000000000000000000003329 168.0
PYH3_k127_8831133_9 binds to the 23S rRNA K02885 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000002332 154.0
PYH3_k127_8897353_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000431 381.0
PYH3_k127_8897353_1 TPR Domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 344.0
PYH3_k127_8897353_2 Uncharacterised protein family (UPF0179) K09730 - - 0.0000000000000000000000000000008459 137.0
PYH3_k127_8897353_3 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.000000002223 60.0
PYH3_k127_8897353_4 - - - - 0.0005322 49.0
PYH3_k127_8938818_0 Subtilase family - - - 0.0000000000000000123 98.0
PYH3_k127_8993827_0 PFAM Multicopper oxidase - - - 8.4e-200 642.0
PYH3_k127_8993827_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.000000000000000000000000000000000000001438 160.0
PYH3_k127_8993827_2 Transcriptional regulator, AbiEi antitoxin - - - 0.0000000000000000000000000004312 121.0
PYH3_k127_9034483_0 Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P). This reaction is the first ether-bond-formation step in the biosynthesis of archaeal membrane lipids K17104 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 2.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000002207 264.0
PYH3_k127_9034483_1 Predicted membrane protein (DUF2070) K08979 - - 0.000000000000000000000000000000000000000000000000000000000000002791 246.0
PYH3_k127_9034483_2 UbiA prenyltransferase family K17105 - 2.5.1.42 0.00000000000000000000000000000000000000000000000000000000003443 214.0
PYH3_k127_9034483_3 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000284 207.0
PYH3_k127_9036986_0 Male sterility protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000001498 223.0
PYH3_k127_9036986_1 exo-alpha-(2->6)-sialidase activity K01186 GO:0001573,GO:0003674,GO:0003824,GO:0004308,GO:0004553,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006629,GO:0006643,GO:0006664,GO:0006665,GO:0006672,GO:0006687,GO:0006689,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016020,GO:0016042,GO:0016052,GO:0016787,GO:0016798,GO:0016997,GO:0019377,GO:0030149,GO:0034641,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043603,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044424,GO:0044464,GO:0046466,GO:0046479,GO:0046514,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575,GO:1903509 3.2.1.18 0.000189 51.0
PYH3_k127_9053007_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002515 582.0
PYH3_k127_9053007_1 4-hydroxy-tetrahydrodipicolinate reductase K00150 - 1.2.1.59 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 430.0
PYH3_k127_9053007_10 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000001693 70.0
PYH3_k127_9053007_11 PIN domain - - - 0.00007058 50.0
PYH3_k127_9053007_12 Uncharacterized protein containing a Zn-ribbon (DUF2116) - - - 0.0008692 46.0
PYH3_k127_9053007_2 Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions K02201 GO:0003674,GO:0003824,GO:0004140,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006732,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0015936,GO:0015937,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000007643 269.0
PYH3_k127_9053007_3 TIGRFAM RNA methyltransferase, TrmH family, group 1 K02533 - - 0.0000000000000000000000000000000000000000000000000000000000001063 220.0
PYH3_k127_9053007_4 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.000000000000000000000000000000000000000000000000002393 191.0
PYH3_k127_9053007_5 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K17884 - 2.7.8.39,2.7.8.5 0.000000000000000000000000000000000000000000000000006141 195.0
PYH3_k127_9053007_6 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.000000000000000000000000000000000005151 150.0
PYH3_k127_9053007_7 - - - - 0.00000000000000000000000000531 110.0
PYH3_k127_9053007_8 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.000000000000000000000000009001 118.0
PYH3_k127_9053007_9 modulator of DNA gyrase K03568 - - 0.0000000000000001161 84.0
PYH3_k127_9065316_0 Rubrerythrin - GO:0003674,GO:0005488,GO:0005506,GO:0006950,GO:0006979,GO:0008150,GO:0043167,GO:0043169,GO:0046872,GO:0046914,GO:0050896 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001546 267.0
PYH3_k127_9065316_1 Protein conserved in bacteria K07192 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002904 265.0
PYH3_k127_9065316_2 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000323 184.0
PYH3_k127_9065316_3 SnoaL-like polyketide cyclase - - - 0.00000000000000000000000000000000000000000000004335 172.0
PYH3_k127_9065316_4 Rubrerythrin - - - 0.0000000000000000000000000000000000003113 146.0
PYH3_k127_9065316_5 Rubrerythrin - - - 0.00000000000000000000000000000000003862 150.0
PYH3_k127_9065316_6 COG0517 FOG CBS domain - - - 0.0000000000218 76.0
PYH3_k127_9065316_7 - - - - 0.000002324 57.0
PYH3_k127_9114546_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1199.0
PYH3_k127_9114546_1 TIGRFAM Acetate-CoA ligase K01895 - 6.2.1.1 1.302e-288 902.0
PYH3_k127_9114546_10 GPR1 FUN34 yaaH family protein K07034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000005103 243.0
PYH3_k127_9114546_11 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000004799 246.0
PYH3_k127_9114546_12 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000006181 205.0
PYH3_k127_9114546_13 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.00000000000000000000000000000000000000000000000000000001564 202.0
PYH3_k127_9114546_14 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000001812 138.0
PYH3_k127_9114546_2 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 419.0
PYH3_k127_9114546_3 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 368.0
PYH3_k127_9114546_4 Catalyzes the decarboxylation of L-tyrosine to produce tyramine for methanofuran biosynthesis. Can also catalyze the decarboxylation of L-aspartate to produce beta-alanine for coenzyme A (CoA) biosynthesis K18933 - 4.1.1.11,4.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003275 343.0
PYH3_k127_9114546_5 ATPase activity K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 323.0
PYH3_k127_9114546_6 transmembrane transport K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 327.0
PYH3_k127_9114546_7 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007459 277.0
PYH3_k127_9114546_8 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003478 263.0
PYH3_k127_9114546_9 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000184 250.0
PYH3_k127_9191581_0 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002381 269.0
PYH3_k127_9191581_1 Subtilase family K17734 - - 0.0000000000000000000000000000000000000000000000000000001144 225.0
PYH3_k127_9191581_2 PhoU domain - - - 0.00000000000000000000000000000000000000000000000000231 195.0
PYH3_k127_9191581_3 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000009344 184.0
PYH3_k127_9191581_4 Lipocalin-like domain - - - 0.0000000000001352 83.0
PYH3_k127_9191581_5 phosphate transporter K03306 GO:0003674,GO:0005215,GO:0005315,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006817,GO:0006820,GO:0008150,GO:0015291,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022804,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0035435,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661 - 0.0000000000008483 74.0
PYH3_k127_9247229_0 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001212 383.0
PYH3_k127_9247229_1 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 332.0
PYH3_k127_9247229_2 Proton-conducting membrane transporter K22168 - 1.5.98.3 0.00000000000000000000000000000000000000000000000000000000000003975 221.0
PYH3_k127_9300566_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000007388 173.0
PYH3_k127_9300566_1 TIGRFAM small GTP-binding protein domain - - - 0.000000000000000000000004256 113.0
PYH3_k127_9300566_2 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.000778 46.0
PYH3_k127_9427861_0 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000001092 180.0
PYH3_k127_9427861_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000009382 163.0
PYH3_k127_9427861_2 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000002899 102.0
PYH3_k127_9518086_0 - - - - 0.00000000000000000000000000000000000000000000000000000001307 214.0
PYH3_k127_9518086_1 calcium- and calmodulin-responsive adenylate cyclase activity - - - 0.000001279 61.0
PYH3_k127_9518086_2 domain, Protein - - - 0.0002419 54.0
PYH3_k127_95950_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 7.655e-257 817.0
PYH3_k127_95950_1 Enoyl-(Acyl carrier protein) reductase K00023,K00059 - 1.1.1.100,1.1.1.36 0.00000000000000000000000000000000000000000000000000000000000000000002131 239.0
PYH3_k127_95950_2 Oxidoreductase, short chain dehydrogenase reductase family protein - - - 0.0000000000000000000000000000000000000000000000000000001217 200.0
PYH3_k127_95950_3 - - - - 0.00000752 52.0
PYH3_k127_95950_4 - - - - 0.0000958 51.0
PYH3_k127_9641726_0 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005299 447.0
PYH3_k127_9641726_1 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004958 413.0
PYH3_k127_9641726_10 SpoVT / AbrB like domain - - - 0.00000002972 57.0
PYH3_k127_9641726_11 AsnC family - - - 0.0000007675 54.0
PYH3_k127_9641726_2 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 389.0
PYH3_k127_9641726_3 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 351.0
PYH3_k127_9641726_4 Helix-hairpin-helix motif K07572 - - 0.0000000000000000000000000000000000000000000000000000000000000000000517 235.0
PYH3_k127_9641726_5 PIN domain - - - 0.00000000000000000000000000005617 120.0
PYH3_k127_9641726_6 Belongs to the eukaryotic ribosomal protein eL21 family K02889 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000131 117.0
PYH3_k127_9641726_7 Binds double-stranded DNA tightly but without sequence specificity. It is distributed uniformly and abundantly on the chromosome, suggesting a role in chromatin architecture. However, it does not significantly compact DNA. Binds rRNA and mRNA in vivo. May play a role in maintaining the structural and functional stability of RNA, and, perhaps, ribosomes K03622 - - 0.00000000000000000000000001052 112.0
PYH3_k127_9641726_8 DNA-directed RNA polymerase subunit F K03051 - 2.7.7.6 0.00000000000003779 76.0
PYH3_k127_9641726_9 Titin Z K12567 GO:0000070,GO:0000228,GO:0000278,GO:0000280,GO:0000793,GO:0000794,GO:0000819,GO:0001701,GO:0001756,GO:0001932,GO:0002020,GO:0002576,GO:0002791,GO:0002793,GO:0003002,GO:0003007,GO:0003008,GO:0003012,GO:0003013,GO:0003015,GO:0003300,GO:0003674,GO:0003779,GO:0003824,GO:0004672,GO:0004674,GO:0004713,GO:0005198,GO:0005200,GO:0005488,GO:0005509,GO:0005515,GO:0005516,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005694,GO:0005737,GO:0005829,GO:0005856,GO:0005859,GO:0005865,GO:0006323,GO:0006464,GO:0006468,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006887,GO:0006928,GO:0006936,GO:0006941,GO:0006996,GO:0007010,GO:0007015,GO:0007049,GO:0007059,GO:0007076,GO:0007154,GO:0007165,GO:0007275,GO:0007389,GO:0007399,GO:0007417,GO:0007420,GO:0007507,GO:0007512,GO:0007517,GO:0008015,GO:0008092,GO:0008150,GO:0008152,GO:0008307,GO:0009581,GO:0009582,GO:0009605,GO:0009612,GO:0009628,GO:0009653,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009893,GO:0009952,GO:0009987,GO:0010035,GO:0010038,GO:0010468,GO:0010604,GO:0010628,GO:0010737,GO:0010927,GO:0014706,GO:0014866,GO:0014896,GO:0014897,GO:0015629,GO:0016043,GO:0016192,GO:0016301,GO:0016310,GO:0016459,GO:0016460,GO:0016740,GO:0016772,GO:0016773,GO:0018108,GO:0018193,GO:0018212,GO:0019220,GO:0019222,GO:0019538,GO:0019899,GO:0019900,GO:0019901,GO:0021591,GO:0022402,GO:0022607,GO:0023052,GO:0030016,GO:0030017,GO:0030018,GO:0030029,GO:0030036,GO:0030048,GO:0030049,GO:0030154,GO:0030239,GO:0030240,GO:0030241,GO:0030261,GO:0030506,GO:0031032,GO:0031033,GO:0031034,GO:0031323,GO:0031399,GO:0031430,GO:0031433,GO:0031672,GO:0031674,GO:0031974,GO:0031981,GO:0032268,GO:0032501,GO:0032502,GO:0032879,GO:0032880,GO:0032940,GO:0032989,GO:0032991,GO:0033058,GO:0033275,GO:0034622,GO:0035051,GO:0035265,GO:0035282,GO:0035556,GO:0035994,GO:0035995,GO:0036211,GO:0036379,GO:0040007,GO:0040011,GO:0042221,GO:0042325,GO:0042692,GO:0042802,GO:0042805,GO:0043009,GO:0043056,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043292,GO:0043412,GO:0043549,GO:0043621,GO:0043933,GO:0044057,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044449,GO:0044464,GO:0044877,GO:0045055,GO:0045214,GO:0045859,GO:0046872,GO:0046903,GO:0048285,GO:0048468,GO:0048513,GO:0048518,GO:0048522,GO:0048589,GO:0048644,GO:0048646,GO:0048729,GO:0048731,GO:0048738,GO:0048739,GO:0048747,GO:0048769,GO:0048856,GO:0048869,GO:0050708,GO:0050714,GO:0050789,GO:0050790,GO:0050794,GO:0050896,GO:0050982,GO:0051015,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051146,GO:0051171,GO:0051174,GO:0051179,GO:0051222,GO:0051223,GO:0051234,GO:0051239,GO:0051246,GO:0051276,GO:0051338,GO:0051371,GO:0051393,GO:0051592,GO:0051606,GO:0051716,GO:0055001,GO:0055002,GO:0055003,GO:0055006,GO:0055007,GO:0055008,GO:0055013,GO:0060047,GO:0060048,GO:0060255,GO:0060322,GO:0060415,GO:0060419,GO:0060429,GO:0060537,GO:0061053,GO:0061061,GO:0065003,GO:0065007,GO:0065009,GO:0070013,GO:0070201,GO:0070252,GO:0070925,GO:0071103,GO:0071688,GO:0071704,GO:0071840,GO:0072359,GO:0080090,GO:0090087,GO:0090257,GO:0097435,GO:0097493,GO:0098813,GO:0099080,GO:0099081,GO:0099512,GO:0140014,GO:0140096,GO:1901077,GO:1901564,GO:1901897,GO:1903047,GO:1903530,GO:1903532,GO:1904951 2.7.11.1 0.000000000369 74.0
PYH3_k127_9670588_0 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000247 606.0
PYH3_k127_9670588_1 Cupin 2, conserved barrel K05916 - 1.14.12.17 0.00000000000000004674 86.0
PYH3_k127_9670588_2 Domain of unknown function (DUF296) K06934 - - 0.0000000000002975 75.0
PYH3_k127_9670588_3 - - - - 0.000000000007092 71.0
PYH3_k127_9670588_4 - - - - 0.00000000001631 66.0
PYH3_k127_9670588_5 Major facilitator superfamily domain containing 11 - - - 0.00000008259 64.0
PYH3_k127_9682830_0 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 557.0
PYH3_k127_9682830_1 Hemerythrin HHE cation binding domain protein K09155 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 452.0
PYH3_k127_9682830_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.000000000000000000000000000000000000000000000000000000000001256 214.0
PYH3_k127_9682830_3 Ferritin-like domain K02217 - 1.16.3.2 0.000000000000000000000000000000000000000000000000000625 189.0
PYH3_k127_9682830_4 ferroxidase activity K03594 GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0009987,GO:0019725,GO:0030003,GO:0042592,GO:0046916,GO:0048878,GO:0050801,GO:0051179,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0065007,GO:0065008,GO:0097577,GO:0098771 1.16.3.1 0.0000000000000000000000000000000000000003229 153.0
PYH3_k127_9682830_5 PFAM Rubredoxin - - - 0.0000000000000000000000008939 105.0
PYH3_k127_9682830_6 PFAM glutaredoxin - - - 0.00005688 52.0
PYH3_k127_973166_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 558.0
PYH3_k127_983730_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 398.0
PYH3_k127_983730_1 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002268 354.0
PYH3_k127_983730_2 ATPase, AAA superfamily K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007133 264.0
PYH3_k127_983730_3 DNA polymerase beta K07076 - - 0.00000000000000000000000792 108.0
PYH3_k127_983730_4 Dam-replacing family - - - 0.0000000000000000000001744 99.0
PYH3_k127_983730_5 Dam-replacing family - - - 0.000000000000000115 82.0
PYH3_k127_983730_6 Dam-replacing family - - - 0.0000000000000003211 79.0
PYH3_k127_983730_7 HEPN domain - - - 0.0000000000000162 80.0
PYH3_k127_983730_8 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.000000002982 68.0