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Overview

ID MAG03221
Name PYH3_bin.26
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Acidobacteriota
Class Terriglobia
Order Terriglobales
Family DASYVL01
Genus DASYVL01
Species
Assembly information
Completeness (%) 70.73
Contamination (%) 1.19
GC content (%) 66.0
N50 (bp) 13,349
Genome size (bp) 1,809,374

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1641

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1037172_0 PFAM glycosyl transferase family 39 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 603.0
PYH3_k127_1037172_1 PFAM Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008836 411.0
PYH3_k127_1037172_2 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 369.0
PYH3_k127_1037172_3 PFAM Protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000002353 251.0
PYH3_k127_1037172_4 TIGRFAM methyltransferase cognate corrinoid proteins, Methanosarcina family K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000002521 192.0
PYH3_k127_1037172_5 Trimethylamine methyltransferase (MTTB) K14083 - 2.1.1.250 0.00000000000000000000000000000000000000000339 166.0
PYH3_k127_1037172_6 NACHT domain - - - 0.0000000000000000000000000000001061 141.0
PYH3_k127_1037172_7 FHA domain containing protein - GO:0005575,GO:0005576,GO:0005623,GO:0005886,GO:0006950,GO:0006979,GO:0008150,GO:0009987,GO:0016020,GO:0040007,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044403,GO:0044419,GO:0044464,GO:0050896,GO:0051301,GO:0051704,GO:0071944 - 0.00001553 57.0
PYH3_k127_1041670_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07788 - - 0.0 1326.0
PYH3_k127_1041670_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 406.0
PYH3_k127_1041670_10 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000002858 116.0
PYH3_k127_1041670_11 Belongs to the ompA family K03640 - - 0.0001807 53.0
PYH3_k127_1041670_2 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009877 359.0
PYH3_k127_1041670_3 Biotin-lipoyl like K07799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 362.0
PYH3_k127_1041670_4 Peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 368.0
PYH3_k127_1041670_5 PFAM sugar transferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007419 282.0
PYH3_k127_1041670_6 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000004728 220.0
PYH3_k127_1041670_7 Formyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000002725 216.0
PYH3_k127_1041670_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000006551 212.0
PYH3_k127_1041670_9 - - - - 0.000000000000000000000000000000000000000000001538 174.0
PYH3_k127_111589_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388,K12527 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6,1.97.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 528.0
PYH3_k127_111589_1 Alginate export - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001813 467.0
PYH3_k127_111589_2 Protein kinase domain K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004988 287.0
PYH3_k127_111589_3 Cytochrome b(N-terminal)/b6/petB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000007547 281.0
PYH3_k127_111589_4 Domain of unknown function (DUF1858) - - - 0.0000000000000000000000000000000000000000000000000000000000000000002748 248.0
PYH3_k127_111589_5 - - - - 0.000000000000000000000000000000008746 130.0
PYH3_k127_111589_6 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.000000000000000000000000005396 119.0
PYH3_k127_111589_7 Transcriptional regulator - - - 0.000000000000000002092 90.0
PYH3_k127_1134414_0 Abhydrolase domain containing 18 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 489.0
PYH3_k127_1134414_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 400.0
PYH3_k127_1134414_2 Enoyl-CoA hydratase/isomerase K01715,K07537 - 4.2.1.100,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003977 367.0
PYH3_k127_1134414_3 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000004331 204.0
PYH3_k127_1134414_4 Ribose/Galactose Isomerase K01808,K01819,K21911 GO:0003674,GO:0003824,GO:0004751,GO:0005975,GO:0008150,GO:0008152,GO:0009056,GO:0009743,GO:0009758,GO:0009987,GO:0010033,GO:0016052,GO:0016853,GO:0016860,GO:0016861,GO:0042221,GO:0044238,GO:0050896,GO:0051716,GO:0070887,GO:0071310,GO:0071322,GO:0071704,GO:1901575,GO:1901700,GO:1901701 5.3.1.26,5.3.1.34,5.3.1.6 0.00000000000000000000000000000000000000000000000000195 186.0
PYH3_k127_1135625_0 MazG-like family - - - 0.00000000000000000000000000005702 117.0
PYH3_k127_1135625_1 Poly(R)-hydroxyalkanoic acid synthase subunit (PHA_synth_III_E) - - - 0.000000000000000000000000007297 123.0
PYH3_k127_1135625_2 PHB de-polymerase C-terminus K03821 - - 0.00000000000000000002267 96.0
PYH3_k127_1184296_0 ABC-type Zn2 transport system, periplasmic component surface adhesin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003583 410.0
PYH3_k127_1184296_1 Protein of unknown function (DUF3341) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003089 250.0
PYH3_k127_1184296_2 Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000008086 236.0
PYH3_k127_1184296_3 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000003163 239.0
PYH3_k127_1184296_4 - - - - 0.000000000003508 73.0
PYH3_k127_1215901_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 3.114e-239 762.0
PYH3_k127_1215901_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.235e-214 681.0
PYH3_k127_1215901_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.426e-199 629.0
PYH3_k127_1215901_3 AIR carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 344.0
PYH3_k127_1215901_4 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001038 270.0
PYH3_k127_1215901_5 NUDIX domain - - - 0.00000000000000000000000000000000000000001641 157.0
PYH3_k127_1215901_6 Winged helix DNA-binding domain - - - 0.000000000000000000000001416 107.0
PYH3_k127_1215901_7 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.000000000000000000000004712 112.0
PYH3_k127_1220247_0 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 565.0
PYH3_k127_1220247_1 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002055 358.0
PYH3_k127_1220247_2 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.00000000000009066 75.0
PYH3_k127_1220247_3 efflux transmembrane transporter activity K02004 - - 0.0000002198 55.0
PYH3_k127_1225704_0 ASPIC and UnbV - - - 0.0 1100.0
PYH3_k127_1225704_1 ASPIC and UnbV - - - 1.288e-261 819.0
PYH3_k127_1225704_2 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000321 585.0
PYH3_k127_1225704_3 Belongs to the amidase family K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001022 353.0
PYH3_k127_1225704_4 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000009344 72.0
PYH3_k127_1257277_0 COG3209 Rhs family protein - - - 5.513e-249 790.0
PYH3_k127_1257277_1 Belongs to the ClpA ClpB family K03696 - - 1.775e-237 741.0
PYH3_k127_1257277_10 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 346.0
PYH3_k127_1257277_11 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007062 288.0
PYH3_k127_1257277_12 methyltransferase activity K00587 - 2.1.1.100 0.0000000000000000000000000000000000000000000008253 172.0
PYH3_k127_1257277_2 SpoIVB peptidase S55 - - - 2.531e-225 713.0
PYH3_k127_1257277_3 MacB-like periplasmic core domain K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 555.0
PYH3_k127_1257277_4 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 521.0
PYH3_k127_1257277_5 ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 481.0
PYH3_k127_1257277_6 von Willebrand factor, type A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002044 428.0
PYH3_k127_1257277_7 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 407.0
PYH3_k127_1257277_8 Peptidase family M48 K03799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 340.0
PYH3_k127_1257277_9 ZIP Zinc transporter K07238,K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 340.0
PYH3_k127_1274324_0 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NADPH and FADH(2) as the reductant - - - 4.233e-212 673.0
PYH3_k127_1274324_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.574e-204 641.0
PYH3_k127_1274324_10 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003754 319.0
PYH3_k127_1274324_11 Phosphomannose isomerase type I K01809 - 5.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 304.0
PYH3_k127_1274324_12 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000004423 233.0
PYH3_k127_1274324_13 LysM domain K13735 GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0009279,GO:0009405,GO:0009987,GO:0016020,GO:0019867,GO:0022610,GO:0030260,GO:0030312,GO:0030313,GO:0031589,GO:0031975,GO:0042710,GO:0043708,GO:0044403,GO:0044409,GO:0044419,GO:0044462,GO:0044464,GO:0044764,GO:0051701,GO:0051704,GO:0051806,GO:0051828,GO:0071944,GO:0090605 - 0.0000000000000000000000000000000000000000000000000000000000000002794 231.0
PYH3_k127_1274324_14 PDZ DHR GLGF domain protein - - - 0.000000000000000000000000000000000000000000000000000000001756 221.0
PYH3_k127_1274324_15 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000000000000000000000424 200.0
PYH3_k127_1274324_16 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000003593 207.0
PYH3_k127_1274324_17 DNA integration K14059 - - 0.000000000000000000000000000000000000000000000000487 183.0
PYH3_k127_1274324_18 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000000006202 140.0
PYH3_k127_1274324_19 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000002766 132.0
PYH3_k127_1274324_2 Amidohydrolase family - - - 1.155e-198 627.0
PYH3_k127_1274324_20 GIY-YIG catalytic domain protein K07461 - - 0.000000000000000000000008611 105.0
PYH3_k127_1274324_21 - - - - 0.00000000000000005566 87.0
PYH3_k127_1274324_3 PFAM Aminotransferase, class I K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000733 595.0
PYH3_k127_1274324_4 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001863 564.0
PYH3_k127_1274324_5 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000391 570.0
PYH3_k127_1274324_6 alpha beta alpha domain I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 538.0
PYH3_k127_1274324_7 mannose-6-phosphate isomerase K00971 - 2.7.7.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 472.0
PYH3_k127_1274324_8 Peptidase M48 K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009503 447.0
PYH3_k127_1274324_9 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 333.0
PYH3_k127_1332279_0 aconitate hydratase K01681 - 4.2.1.3 1.034e-230 723.0
PYH3_k127_1332279_1 TIGRFAM hopanoid biosynthesis associated glycosyl transferase protein HpnI K00720 - 2.4.1.80 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008178 318.0
PYH3_k127_1332279_10 alkyl hydroperoxide reductase K03386,K03564 - 1.11.1.15 0.00000005854 55.0
PYH3_k127_1332279_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 311.0
PYH3_k127_1332279_3 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009167 252.0
PYH3_k127_1332279_4 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000007751 240.0
PYH3_k127_1332279_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000013 228.0
PYH3_k127_1332279_6 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000003311 184.0
PYH3_k127_1332279_7 peroxiredoxin activity K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000113 161.0
PYH3_k127_1332279_8 membrane K08978 - - 0.000000000000000000003657 101.0
PYH3_k127_1332279_9 EamA-like transporter family - - - 0.000000000000000001399 92.0
PYH3_k127_1343684_0 Acyl-CoA dehydrogenase, C-terminal domain K00252 - 1.3.8.6 1.02e-211 663.0
PYH3_k127_1343684_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded K02446 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004312 447.0
PYH3_k127_1343684_2 arylsulfatase activity K07014 - - 0.000000000000001054 86.0
PYH3_k127_1367119_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 439.0
PYH3_k127_1367119_1 PFAM peptidase K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000002062 251.0
PYH3_k127_1413592_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001148 566.0
PYH3_k127_1413592_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001895 515.0
PYH3_k127_1413592_10 Domain of unknown function (DUF1844) - - - 0.000000000000000000000001104 106.0
PYH3_k127_1413592_2 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 409.0
PYH3_k127_1413592_3 3-beta hydroxysteroid dehydrogenase/isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 402.0
PYH3_k127_1413592_4 Metallo-beta-lactamase superfamily K06167 - 3.1.4.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 393.0
PYH3_k127_1413592_5 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005515 381.0
PYH3_k127_1413592_6 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 344.0
PYH3_k127_1413592_7 spore germination - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 306.0
PYH3_k127_1413592_8 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.00000000000000000000000000000000000000001452 164.0
PYH3_k127_1413592_9 OsmC-like protein K07397 - - 0.00000000000000000000000000000000000003717 146.0
PYH3_k127_142667_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1327.0
PYH3_k127_142667_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000418 289.0
PYH3_k127_142667_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000007231 168.0
PYH3_k127_142667_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000002613 80.0
PYH3_k127_14442_0 Alpha/beta hydrolase family - - - 1.694e-275 865.0
PYH3_k127_14442_1 CoA binding domain K09181 - - 2.855e-233 734.0
PYH3_k127_1444357_0 Peptidase family M1 domain - - - 3.625e-201 635.0
PYH3_k127_1444357_1 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000003385 194.0
PYH3_k127_1461616_0 Heat shock 70 kDa protein K04043 - - 0.0 1046.0
PYH3_k127_1461616_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.186e-319 984.0
PYH3_k127_1461616_2 Two component transcriptional regulator, LytTR family K02477,K07705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002829 408.0
PYH3_k127_1461616_3 Catalyzes the final step of fatty acid oxidation in which acetyl-CoA is released and the CoA ester of a fatty acid two carbons shorter is formed K00626 GO:0003674,GO:0003824,GO:0003988,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016408,GO:0016740,GO:0016746,GO:0016747,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006805 410.0
PYH3_k127_1461616_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000002041 207.0
PYH3_k127_1461616_5 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000000000000000000001017 150.0
PYH3_k127_1461616_6 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000003524 123.0
PYH3_k127_1461616_7 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.000000000000000000279 102.0
PYH3_k127_1485602_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1249.0
PYH3_k127_1485602_1 PFAM Band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 434.0
PYH3_k127_1485602_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000784 252.0
PYH3_k127_1485602_3 - - - - 0.0000000000000000000000000000000000000000000000000006372 195.0
PYH3_k127_1485602_4 PFAM Cupin 2, conserved barrel - - - 0.0000000000000000000000000000000000000000000000004261 177.0
PYH3_k127_1485602_5 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.00000000000000000000000000000000000007929 149.0
PYH3_k127_1485602_6 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.00000000000000000000000000000000000009842 143.0
PYH3_k127_1485602_7 - - - - 0.000000000000000000000000000000002062 136.0
PYH3_k127_1485602_8 cellular response to DNA damage stimulus K07340 - - 0.00000000000000000000000000000002563 130.0
PYH3_k127_1485602_9 DinB superfamily K07552 - - 0.0000000000000000000000000005795 129.0
PYH3_k127_1534924_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 3.588e-240 749.0
PYH3_k127_1534924_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000748 376.0
PYH3_k127_1534924_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006893 351.0
PYH3_k127_1534924_3 nitrite transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 347.0
PYH3_k127_1534924_4 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001916 336.0
PYH3_k127_1534924_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0006002,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016829,GO:0016830,GO:0016832,GO:0019637,GO:0044237,GO:0071704,GO:1901135 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002199 304.0
PYH3_k127_1534924_6 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008209 295.0
PYH3_k127_1534924_7 Fibronectin type 3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003114 244.0
PYH3_k127_1534924_8 IMP dehydrogenase activity - - - 0.0000000000000000000000000000000006207 136.0
PYH3_k127_1545383_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 4.34e-202 638.0
PYH3_k127_1545383_1 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 9.15e-196 624.0
PYH3_k127_1545383_2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003279 602.0
PYH3_k127_1545383_3 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 540.0
PYH3_k127_1545383_4 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 526.0
PYH3_k127_1545383_5 Belongs to the SEDS family K03588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 489.0
PYH3_k127_1545383_6 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003945 414.0
PYH3_k127_1545383_7 Cell division protein FtsQ K03589 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 347.0
PYH3_k127_1545383_8 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.0000000000000000000000000000000000000000000000000000000000001939 215.0
PYH3_k127_1549495_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002304 561.0
PYH3_k127_1549495_1 Radical SAM superfamily K04069 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 497.0
PYH3_k127_1549495_2 WD40 domain protein beta Propeller K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001429 280.0
PYH3_k127_1549495_3 Carbonic anhydrase K01673 - 4.2.1.1 0.00000000000000000000000000000000000000000000000000000000000135 216.0
PYH3_k127_1549495_4 PFAM Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000006132 161.0
PYH3_k127_1549495_5 Chromate resistance exported protein - - - 0.000000000000000000000000000000000000002489 153.0
PYH3_k127_1549495_6 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000001775 132.0
PYH3_k127_1549495_7 Beta-agarase K01219 - 3.2.1.81 0.00000000000000000000000002013 126.0
PYH3_k127_1549495_8 Domain of unknown function (DUF4349) - - - 0.0000000000000000000002275 109.0
PYH3_k127_1611497_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.577e-278 866.0
PYH3_k127_1611497_1 PFAM Iron permease FTR1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 345.0
PYH3_k127_1611497_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 345.0
PYH3_k127_1611497_3 nucleotide metabolic process - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 328.0
PYH3_k127_1611497_4 - - - - 0.00000000000000000000000003739 116.0
PYH3_k127_1611497_5 - - - - 0.0000000006746 67.0
PYH3_k127_1616397_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007241 358.0
PYH3_k127_1616397_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000001677 201.0
PYH3_k127_1616397_2 Pyridoxal-dependent decarboxylase conserved domain - - - 0.00000000000000000000000000000000000005483 147.0
PYH3_k127_1633784_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1166.0
PYH3_k127_1633784_1 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009506 453.0
PYH3_k127_1633784_10 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000008698 153.0
PYH3_k127_1633784_2 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 432.0
PYH3_k127_1633784_3 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006965 423.0
PYH3_k127_1633784_4 TIGRFAM Outer membrane assembly lipoprotein YfiO K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 409.0
PYH3_k127_1633784_5 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006067 401.0
PYH3_k127_1633784_6 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 327.0
PYH3_k127_1633784_7 outer membrane autotransporter barrel domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003414 259.0
PYH3_k127_1633784_8 serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000001306 244.0
PYH3_k127_1670490_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 4.489e-207 651.0
PYH3_k127_1670490_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 555.0
PYH3_k127_1670490_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 370.0
PYH3_k127_1673217_0 Penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 0.0 1033.0
PYH3_k127_1673217_1 HypF finger K04656 - - 3.047e-279 878.0
PYH3_k127_1673217_10 PASTA domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000001749 210.0
PYH3_k127_1673217_12 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000001221 119.0
PYH3_k127_1673217_13 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000006578 66.0
PYH3_k127_1673217_14 - - - - 0.000000006735 63.0
PYH3_k127_1673217_2 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 5.133e-252 818.0
PYH3_k127_1673217_3 Heavy metal translocating P-type atpase - - - 1.506e-232 735.0
PYH3_k127_1673217_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K03737 - 1.2.7.1 7.185e-204 677.0
PYH3_k127_1673217_5 Aspartate-ammonia ligase K01914 - 6.3.1.1 1.624e-198 625.0
PYH3_k127_1673217_6 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 479.0
PYH3_k127_1673217_7 Iron-sulfur cluster-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 463.0
PYH3_k127_1673217_8 Aminotransferase K00812,K10907 - 2.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 464.0
PYH3_k127_1673217_9 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 334.0
PYH3_k127_1758570_0 Transferrin receptor-like dimerisation domain K01301 - 3.4.17.21 4.455e-279 876.0
PYH3_k127_1758570_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 7.534e-266 824.0
PYH3_k127_1758570_10 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000000000004621 115.0
PYH3_k127_1758570_11 Cupin domain - - - 0.000000009632 63.0
PYH3_k127_1758570_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K07516 - 1.1.1.35 4.059e-227 721.0
PYH3_k127_1758570_3 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 415.0
PYH3_k127_1758570_4 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001066 365.0
PYH3_k127_1758570_5 Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 364.0
PYH3_k127_1758570_6 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000001892 184.0
PYH3_k127_1758570_7 ABC transporter - - - 0.0000000000000000000000000000000000000000000008268 170.0
PYH3_k127_1758570_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.0000000000000000000000000000000000000000001279 164.0
PYH3_k127_1758570_9 Histidine phosphatase superfamily (branch 1) - - - 0.0000000000000000000000000193 119.0
PYH3_k127_1823665_0 Sortilin, neurotensin receptor 3, - - - 0.0 1375.0
PYH3_k127_1823665_1 PFAM Amidase - - - 6.412e-249 782.0
PYH3_k127_1823665_10 Inner membrane component of T3SS, cytoplasmic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002245 400.0
PYH3_k127_1823665_11 lysine biosynthetic process via aminoadipic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000606 424.0
PYH3_k127_1823665_12 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001723 376.0
PYH3_k127_1823665_13 COGs COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 364.0
PYH3_k127_1823665_14 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003683 340.0
PYH3_k127_1823665_15 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004637 301.0
PYH3_k127_1823665_16 3-demethylubiquinone-9 3-O-methyltransferase activity K16328 - 2.7.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003436 284.0
PYH3_k127_1823665_17 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003738 284.0
PYH3_k127_1823665_18 MOSC domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001672 286.0
PYH3_k127_1823665_19 Domain of Unknown function (DUF542) K07322 - - 0.00000000000000000000000000000000000000000000000000000000000000000006934 240.0
PYH3_k127_1823665_2 PA domain - - - 5.959e-223 706.0
PYH3_k127_1823665_20 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.0000000000000000000000000000000000000000000000003155 177.0
PYH3_k127_1823665_21 domain, Protein K02014,K12287,K16087 - - 0.0000000000000000000000000000000000000006727 173.0
PYH3_k127_1823665_22 - - - - 0.0000000000000000000000000000000000006858 149.0
PYH3_k127_1823665_23 sigma factor antagonist activity K04757,K17752 - 2.7.11.1 0.0000000000000000000000000000006863 127.0
PYH3_k127_1823665_24 Zincin-like metallopeptidase - - - 0.00000000000000000008247 101.0
PYH3_k127_1823665_25 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000001624 97.0
PYH3_k127_1823665_26 YceI-like domain - - - 0.00000000000000148 93.0
PYH3_k127_1823665_28 amine dehydrogenase activity - - - 0.000000000002458 82.0
PYH3_k127_1823665_3 Protein kinase domain K12132 - 2.7.11.1 2.506e-212 689.0
PYH3_k127_1823665_4 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006904 565.0
PYH3_k127_1823665_5 PFAM peptidase S8 and S53 subtilisin kexin sedolisin K08651 - 3.4.21.66 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009298 576.0
PYH3_k127_1823665_6 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008807 501.0
PYH3_k127_1823665_7 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004537 448.0
PYH3_k127_1823665_8 WD40-like Beta Propeller Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 445.0
PYH3_k127_1923485_0 heat shock protein binding - - - 4.338e-249 785.0
PYH3_k127_1923485_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005159 494.0
PYH3_k127_1923485_2 PFAM FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 474.0
PYH3_k127_1923485_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002042 282.0
PYH3_k127_2132118_0 Alpha beta hydrolase K03821 - - 2.177e-233 735.0
PYH3_k127_2132118_1 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000004009 244.0
PYH3_k127_2135316_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003742 329.0
PYH3_k127_2218354_0 domain protein - - - 0.0 1124.0
PYH3_k127_2218354_1 ASPIC and UnbV - - - 6.389e-268 844.0
PYH3_k127_2218354_10 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000008331 121.0
PYH3_k127_2218354_2 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 1.145e-254 794.0
PYH3_k127_2218354_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 480.0
PYH3_k127_2218354_4 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 332.0
PYH3_k127_2218354_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000006453 239.0
PYH3_k127_2218354_6 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000002201 230.0
PYH3_k127_2218354_7 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000000000000000000000009665 207.0
PYH3_k127_2218354_8 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000000000000000000000001623 183.0
PYH3_k127_2218354_9 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000001968 170.0
PYH3_k127_221956_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.574e-219 687.0
PYH3_k127_221956_1 Belongs to the purine pyrimidine phosphoribosyltransferase family K00760 GO:0000287,GO:0003674,GO:0003824,GO:0004422,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006163,GO:0006164,GO:0006166,GO:0006177,GO:0006188,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032261,GO:0032263,GO:0032264,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0043094,GO:0043101,GO:0043167,GO:0043169,GO:0043173,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046037,GO:0046040,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.8 0.00000000000000000000000000000000000000000000000000000187 197.0
PYH3_k127_2274391_0 peptidase K01415,K07386 - 3.4.24.71 1.506e-200 647.0
PYH3_k127_2274391_1 Belongs to the thiolase family K00626,K07508 - 2.3.1.16,2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 468.0
PYH3_k127_2274391_2 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009119 458.0
PYH3_k127_2274391_3 GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003908 426.0
PYH3_k127_2274391_4 Enoyl-CoA hydratase/isomerase K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004363 349.0
PYH3_k127_2274391_5 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008519 301.0
PYH3_k127_2505043_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.0 1234.0
PYH3_k127_2505043_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 548.0
PYH3_k127_2505043_10 Histidine kinase - - - 0.000001824 53.0
PYH3_k127_2505043_2 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 512.0
PYH3_k127_2505043_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 510.0
PYH3_k127_2505043_4 PFAM binding-protein-dependent transport systems inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 494.0
PYH3_k127_2505043_5 Transporter associated domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 491.0
PYH3_k127_2505043_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000376 434.0
PYH3_k127_2505043_7 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009738 324.0
PYH3_k127_2505043_8 Mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003649 287.0
PYH3_k127_2505043_9 - - - - 0.00000000002274 74.0
PYH3_k127_2526851_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 9.323e-271 848.0
PYH3_k127_2526851_1 phenylalanyl-tRNA synthetase beta subunit K01890 - 6.1.1.20 1.888e-256 807.0
PYH3_k127_2526851_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000003364 253.0
PYH3_k127_2526851_11 COG0079 Histidinol-phosphate aromatic aminotransferase and cobyric acid decarboxylase K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000001936 200.0
PYH3_k127_2526851_12 - - - - 0.0000000000000000000000000000000000000000000000000007339 188.0
PYH3_k127_2526851_13 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000008951 180.0
PYH3_k127_2526851_14 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000000000000000002386 172.0
PYH3_k127_2526851_15 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000387 105.0
PYH3_k127_2526851_16 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000003795 88.0
PYH3_k127_2526851_17 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.000000005768 67.0
PYH3_k127_2526851_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 5.657e-250 785.0
PYH3_k127_2526851_3 synthetase, class II (G H P K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 589.0
PYH3_k127_2526851_4 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 511.0
PYH3_k127_2526851_5 Carboxypeptidase regulatory-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 498.0
PYH3_k127_2526851_6 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 406.0
PYH3_k127_2526851_7 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
PYH3_k127_2526851_8 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000285 282.0
PYH3_k127_2526851_9 Winged helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003035 269.0
PYH3_k127_2558096_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 596.0
PYH3_k127_2558096_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006825 327.0
PYH3_k127_2558096_2 CoA binding domain K06929 - - 0.000000000000000000000000000000000000000000000000000001111 199.0
PYH3_k127_2558096_3 Helix-turn-helix domain - - - 0.000000000000000000000000000000005125 140.0
PYH3_k127_2558096_4 - - - - 0.000000000000000000000001366 109.0
PYH3_k127_2558096_5 - - - - 0.0000000000000007774 85.0
PYH3_k127_2702328_0 radical SAM domain protein K22318 - - 1.228e-253 794.0
PYH3_k127_2702328_1 Periplasmic or secreted lipoprotein - - - 0.0000000001614 62.0
PYH3_k127_2770339_0 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 6.59e-220 715.0
PYH3_k127_2770339_1 homocysteine S-methyltransferase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002549 453.0
PYH3_k127_2770339_10 PKD domain containing protein - - - 0.0000001139 62.0
PYH3_k127_2770339_2 Belongs to the FPP GGPP synthase family K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 428.0
PYH3_k127_2770339_3 GlcNAc-PI de-N-acetylase K01463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 345.0
PYH3_k127_2770339_4 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001286 312.0
PYH3_k127_2770339_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004498 311.0
PYH3_k127_2770339_6 O-methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000016 259.0
PYH3_k127_2770339_7 PFAM Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000008689 189.0
PYH3_k127_2770339_8 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000000000005354 106.0
PYH3_k127_2774570_0 Histidine kinase K02482 - 2.7.13.3 6.122e-254 803.0
PYH3_k127_2774570_1 Bacterial regulatory protein, Fis family - - - 5.139e-202 645.0
PYH3_k127_2774570_10 Chemotaxis signal transduction protein K03408 - - 0.00000000000005855 83.0
PYH3_k127_2774570_2 Two component signalling adaptor domain K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005374 376.0
PYH3_k127_2774570_3 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660,K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000481 329.0
PYH3_k127_2774570_5 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000006318 206.0
PYH3_k127_2774570_6 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000001013 179.0
PYH3_k127_2774570_7 Response regulator, receiver - - - 0.0000000000000000000000000000000000000006102 155.0
PYH3_k127_2774570_8 cheY-homologous receiver domain K02658 - - 0.000000000000000000000000000000000003454 141.0
PYH3_k127_2881193_0 TIGRFAM molybdenum cofactor synthesis K03750 - 2.10.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004844 388.0
PYH3_k127_2881193_1 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 337.0
PYH3_k127_2881193_2 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000007745 205.0
PYH3_k127_2881193_3 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000002408 143.0
PYH3_k127_2929044_0 Domain of unknown function (DUF3488) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009228 539.0
PYH3_k127_2930648_0 beta-N-acetylhexosaminidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009879 556.0
PYH3_k127_2930648_1 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001474 360.0
PYH3_k127_2945379_0 Tetratricopeptide repeat - - - 2.444e-268 841.0
PYH3_k127_2945379_1 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006643 589.0
PYH3_k127_2945379_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 487.0
PYH3_k127_2945379_3 Cation efflux family K16264 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 389.0
PYH3_k127_2945379_4 diguanylate cyclase activity K13069 GO:0003674,GO:0003824,GO:0016740,GO:0016772,GO:0016779,GO:0052621 2.7.7.65 0.000000000000000000000000000000000000000000000000000000178 205.0
PYH3_k127_2945379_5 Transposase IS200 like K07491 - - 0.0000000000000000000004512 98.0
PYH3_k127_2945379_6 Protein of unknown function (DUF1385) - - - 0.0000000000000000756 82.0
PYH3_k127_2945379_7 Transposase IS200 like K07491 - - 0.0000000002734 64.0
PYH3_k127_3022533_0 glycosyl transferase group 1 K00754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 567.0
PYH3_k127_3022533_1 Serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 520.0
PYH3_k127_3022533_2 Histidine kinase K02478 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 357.0
PYH3_k127_3022533_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K04750 - - 0.00000000000000000000000000000000000000000000000000000000000000001257 228.0
PYH3_k127_3022533_4 - - - - 0.000000000000000000000000000000000000000003244 159.0
PYH3_k127_3022533_5 Protein of unknown function (DUF1189) - - - 0.00000000000000001091 93.0
PYH3_k127_3031183_0 ATP-dependent DNA helicase RecG K03655 - 3.6.4.12 0.0 1018.0
PYH3_k127_3031183_1 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 500.0
PYH3_k127_3031183_2 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007896 394.0
PYH3_k127_3031183_3 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 358.0
PYH3_k127_3031183_4 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000000000007771 207.0
PYH3_k127_3031183_5 Predicted membrane protein (DUF2207) - - - 0.00000000000000000000000000000000000000000000000005786 193.0
PYH3_k127_3031183_6 oxidoreductase activity - - - 0.000000000000000000000000000001409 128.0
PYH3_k127_3031183_7 TonB-dependent Receptor Plug Domain K02014,K16092 - - 0.000000000000000000000001055 113.0
PYH3_k127_3031183_8 GGDEF domain - - - 0.0000001117 65.0
PYH3_k127_3153714_0 two component, sigma54 specific, transcriptional regulator, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 579.0
PYH3_k127_3153714_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004477 582.0
PYH3_k127_3153714_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 462.0
PYH3_k127_3153714_3 Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001914 456.0
PYH3_k127_3153714_4 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 334.0
PYH3_k127_3153714_5 Glycine cleavage H-protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000002544 240.0
PYH3_k127_3153714_6 Peptidase family M54 K06974 - - 0.00000000000000000000000000000000000000000000000000000000004322 211.0
PYH3_k127_3278175_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 3.6e-291 905.0
PYH3_k127_3278175_1 Protein tyrosine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005806 362.0
PYH3_k127_3278175_2 Iron-containing redox enzyme K06137 - 1.3.3.11 0.000000000000000000000000000000000000000000000000000000000000000006963 233.0
PYH3_k127_3278175_3 Thioesterase K18700 - 3.1.2.29 0.000000000000000000002678 102.0
PYH3_k127_3278175_4 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0002845 44.0
PYH3_k127_3323226_0 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 590.0
PYH3_k127_3323226_1 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 413.0
PYH3_k127_3323226_2 Protein kinase domain K08884 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000003579 231.0
PYH3_k127_3323226_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000002094 194.0
PYH3_k127_3323226_4 - - - - 0.00000000000000000000000000000000000000002618 158.0
PYH3_k127_3401963_0 TIGRFAM carbamoyl-phosphate synthase, large subunit K01955 - 6.3.5.5 0.0 1701.0
PYH3_k127_3401963_1 TIGRFAM Carbamoyl-phosphate synthase, small subunit K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 603.0
PYH3_k127_3401963_10 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.00000000000000000000000000000000000000000000000003041 181.0
PYH3_k127_3401963_11 Protein of unknown function with PCYCGC motif - - - 0.000000000000000000000000000000000000000005972 172.0
PYH3_k127_3401963_12 PFAM Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.000000000000003534 80.0
PYH3_k127_3401963_14 PFAM Saccharopine dehydrogenase - - - 0.000001955 60.0
PYH3_k127_3401963_15 domain protein - - - 0.0003189 51.0
PYH3_k127_3401963_2 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 580.0
PYH3_k127_3401963_3 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000307 562.0
PYH3_k127_3401963_4 Membrane dipeptidase (Peptidase family M19) K01273 - 3.4.13.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 416.0
PYH3_k127_3401963_5 Required for morphogenesis under gluconeogenic growth conditions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 392.0
PYH3_k127_3401963_6 major pilin protein fima - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004707 384.0
PYH3_k127_3401963_7 amine dehydrogenase activity K17285 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007294 318.0
PYH3_k127_3401963_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000003619 262.0
PYH3_k127_3401963_9 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000009376 227.0
PYH3_k127_3446868_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 2.684e-278 872.0
PYH3_k127_3446868_1 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 2.559e-234 733.0
PYH3_k127_3446868_10 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 402.0
PYH3_k127_3446868_11 TrkA-C domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008301 383.0
PYH3_k127_3446868_12 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 362.0
PYH3_k127_3446868_13 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 299.0
PYH3_k127_3446868_14 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003748 267.0
PYH3_k127_3446868_15 PFAM thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000007371 231.0
PYH3_k127_3446868_16 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.0000000000000000000000000000000000000000000000003595 182.0
PYH3_k127_3446868_17 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.0000000000000000000000000000000000000000000368 165.0
PYH3_k127_3446868_18 DinB superfamily - - - 0.000000000000000000000000000000000000000003778 164.0
PYH3_k127_3446868_19 amino acid K03294 - - 0.000000000000000000000000000000000000000954 149.0
PYH3_k127_3446868_2 von Willebrand factor (vWF) type A domain K07114 - - 9.717e-210 662.0
PYH3_k127_3446868_20 chaperone-mediated protein folding - - - 0.00000000000000000000000000000001573 129.0
PYH3_k127_3446868_21 PFAM Iron sulphur-containing domain, CDGSH-type - - - 0.000000000000000000004329 96.0
PYH3_k127_3446868_22 - - - - 0.000000000000000001559 97.0
PYH3_k127_3446868_23 Glutathione peroxidase K02199 - - 0.000000000000002117 90.0
PYH3_k127_3446868_24 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000002483 70.0
PYH3_k127_3446868_25 Tetratricopeptide repeat - - - 0.0002902 53.0
PYH3_k127_3446868_3 Two component regulator propeller - - - 1.389e-208 672.0
PYH3_k127_3446868_4 peptidoglycan turnover K06958,K07102 GO:0000166,GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005975,GO:0006022,GO:0006040,GO:0006082,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009254,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0017076,GO:0019200,GO:0019752,GO:0030203,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0046835,GO:0071704,GO:0097159,GO:0097172,GO:0097367,GO:1901135,GO:1901265,GO:1901363,GO:1901564 2.7.1.221 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 610.0
PYH3_k127_3446868_5 C-terminus of AA_permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 557.0
PYH3_k127_3446868_6 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 453.0
PYH3_k127_3446868_7 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 461.0
PYH3_k127_3446868_8 Major facilitator Superfamily K08152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 455.0
PYH3_k127_3446868_9 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 416.0
PYH3_k127_356983_0 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 505.0
PYH3_k127_356983_1 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.000000000000000000003088 94.0
PYH3_k127_357571_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 9.148e-295 916.0
PYH3_k127_357571_1 Metallopeptidase family M24 K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005149 526.0
PYH3_k127_357571_10 Belongs to the UPF0235 family K09131 - - 0.000000000000000000001135 106.0
PYH3_k127_357571_11 - - - - 0.000000000000001816 85.0
PYH3_k127_357571_2 oligopeptide transport K03305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 526.0
PYH3_k127_357571_3 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 506.0
PYH3_k127_357571_4 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 419.0
PYH3_k127_357571_5 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001088 254.0
PYH3_k127_357571_6 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000002304 230.0
PYH3_k127_357571_7 - - - - 0.000000000000000000000000000000000000000503 157.0
PYH3_k127_357571_8 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000000000000000002201 130.0
PYH3_k127_357571_9 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.000000000000000000000000000000004217 132.0
PYH3_k127_3609_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 1.792e-209 658.0
PYH3_k127_3609_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 600.0
PYH3_k127_3609_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 482.0
PYH3_k127_3609_3 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000008276 250.0
PYH3_k127_3609_4 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000001157 218.0
PYH3_k127_3609_5 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000004945 141.0
PYH3_k127_3609_6 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000001797 126.0
PYH3_k127_3609_7 isomerase activity K01821 - 5.3.2.6 0.0000000000001414 73.0
PYH3_k127_3654833_0 Carboxypeptidase regulatory-like domain - - - 0.0 1213.0
PYH3_k127_3654833_1 Electron transfer flavoprotein-ubiquinone oxidoreductase, 4Fe-4S K00311 - 1.5.5.1 2.886e-315 971.0
PYH3_k127_3654833_11 Phenazine biosynthesis protein, PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006781 323.0
PYH3_k127_3654833_12 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002283 319.0
PYH3_k127_3654833_13 Protein of unknown function DUF72 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001893 269.0
PYH3_k127_3654833_14 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.0000000000000000000000000000000000000000000000001505 186.0
PYH3_k127_3654833_15 PFAM response regulator receiver - - - 0.00000000000000000000000000000000000000000002856 165.0
PYH3_k127_3654833_16 Uncharacterized conserved protein (DUF2203) - - - 0.000000000000000000000000000000000000000003593 171.0
PYH3_k127_3654833_17 - - - - 0.000000000000000000000000000000000000000004621 155.0
PYH3_k127_3654833_18 Stage II sporulation protein K06381 - - 0.00000000000000000000000000000000002235 150.0
PYH3_k127_3654833_19 phosphorelay signal transduction system - - - 0.0000000000000000000000192 109.0
PYH3_k127_3654833_2 DNA ligase D, 3'-phosphoesterase domain K01971 - 6.5.1.1 1.515e-292 920.0
PYH3_k127_3654833_20 antisigma factor binding K03409,K04749,K07122 - - 0.0000000000000000000001619 104.0
PYH3_k127_3654833_21 Lactonase, 7-bladed beta-propeller - - - 0.000000000000004287 83.0
PYH3_k127_3654833_22 Copper resistance protein D K07245 - - 0.00000000000005884 83.0
PYH3_k127_3654833_23 - - - - 0.0000000001598 64.0
PYH3_k127_3654833_24 - - - - 0.000000002835 68.0
PYH3_k127_3654833_25 Pfam Condensation domain - - - 0.0000005968 56.0
PYH3_k127_3654833_26 penicillin binding K05515 - 3.4.16.4 0.000004625 59.0
PYH3_k127_3654833_3 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 576.0
PYH3_k127_3654833_4 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007004 528.0
PYH3_k127_3654833_5 Electron transfer flavoprotein FAD-binding domain K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 481.0
PYH3_k127_3654833_6 Electron transfer flavoprotein domain K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 447.0
PYH3_k127_3654833_7 Inner membrane component of T3SS, cytoplasmic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 449.0
PYH3_k127_3654833_8 YVTN family beta-propeller repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 392.0
PYH3_k127_3654833_9 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 378.0
PYH3_k127_3803002_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 374.0
PYH3_k127_3803002_1 galactose-1-phosphate K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 366.0
PYH3_k127_3803002_3 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.00000000000000000000000002015 115.0
PYH3_k127_3803002_4 Putative adhesin - - - 0.000004053 57.0
PYH3_k127_3880670_0 Carboxyl transferase domain K01966 - 2.1.3.15,6.4.1.3 1.59e-286 887.0
PYH3_k127_3880670_1 Protein kinase domain K12132 - 2.7.11.1 1.126e-258 824.0
PYH3_k127_3880670_2 PFAM Major facilitator superfamily K08178 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 538.0
PYH3_k127_3880670_3 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000111 283.0
PYH3_k127_3880670_4 stress-induced mitochondrial fusion - - - 0.0000000000000000000000000000000000000000000000000000000000000009448 233.0
PYH3_k127_3880670_6 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.000000000888 60.0
PYH3_k127_3892723_0 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 3.023e-197 620.0
PYH3_k127_3892723_1 Domain of unknown function (DUF2437) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 366.0
PYH3_k127_3892723_2 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000933 287.0
PYH3_k127_3892723_3 Luciferase-like monooxygenase K00320 - 1.5.98.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000006192 277.0
PYH3_k127_3892723_4 Tryptophan 2,3-dioxygenase K00453 - 1.13.11.11 0.00000000000000000000000000000000000000000000204 179.0
PYH3_k127_3892723_5 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000001249 85.0
PYH3_k127_3892723_6 - - - - 0.00000000000121 78.0
PYH3_k127_3910204_0 Glycosyl transferase, family 2 - - - 0.0 1260.0
PYH3_k127_3910204_1 Delta-1-pyrroline-5-carboxylate dehydrogenase K00294 - 1.2.1.88 6.868e-249 777.0
PYH3_k127_3910204_10 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000002097 165.0
PYH3_k127_3910204_11 - - - - 0.000000000000000000000005183 108.0
PYH3_k127_3910204_12 PilZ domain - - - 0.00000000000000000000001926 104.0
PYH3_k127_3910204_14 PBS lyase HEAT-like repeat - - - 0.0000000000005533 83.0
PYH3_k127_3910204_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006428 560.0
PYH3_k127_3910204_3 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 543.0
PYH3_k127_3910204_4 membrane protein (DUF2207) - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000179 421.0
PYH3_k127_3910204_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003636 400.0
PYH3_k127_3910204_6 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000414 284.0
PYH3_k127_3910204_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.00000000000000000000000000000000000000000000000000000000000000009879 229.0
PYH3_k127_3910204_8 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000002202 205.0
PYH3_k127_3910204_9 Catalyzes the conversion of dihydroorotate to orotate K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000008634 168.0
PYH3_k127_3914254_0 Vitamin B12 dependent methionine synthase activation K00548 - 2.1.1.13 0.0 1662.0
PYH3_k127_3914254_1 Belongs to the UbiD family K03182 - 4.1.1.98 1.126e-258 807.0
PYH3_k127_3914254_10 glutamine synthetase K01915 GO:0001968,GO:0003674,GO:0003824,GO:0004356,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006541,GO:0006542,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009405,GO:0009605,GO:0009607,GO:0009893,GO:0009987,GO:0010468,GO:0010604,GO:0010628,GO:0010755,GO:0010756,GO:0010954,GO:0016020,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019222,GO:0019752,GO:0019899,GO:0020012,GO:0030162,GO:0030312,GO:0030682,GO:0031323,GO:0031325,GO:0032268,GO:0032270,GO:0035375,GO:0040007,GO:0043207,GO:0043436,GO:0044044,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0045862,GO:0046394,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0051701,GO:0051704,GO:0051707,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0052173,GO:0052200,GO:0052564,GO:0052572,GO:0060255,GO:0065007,GO:0070613,GO:0071704,GO:0071944,GO:0075136,GO:0080090,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1903317,GO:1903319 6.3.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000002003 264.0
PYH3_k127_3914254_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000003342 263.0
PYH3_k127_3914254_12 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.00000000000000000000000000000000000000000000000000000000000001526 220.0
PYH3_k127_3914254_13 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.0000000000000000000000000000000000000000000000000000000000001345 215.0
PYH3_k127_3914254_14 Belongs to the MsrB Met sulfoxide reductase family K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000000000002267 211.0
PYH3_k127_3914254_15 - - - - 0.00000004526 54.0
PYH3_k127_3914254_2 Pyridoxal-dependent decarboxylase conserved domain K01593,K01634 - 4.1.1.105,4.1.1.28,4.1.2.27 2.596e-209 660.0
PYH3_k127_3914254_3 Belongs to the deoxyhypusine synthase family K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 556.0
PYH3_k127_3914254_4 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001945 493.0
PYH3_k127_3914254_5 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009016 470.0
PYH3_k127_3914254_6 Belongs to the agmatine deiminase family K10536 - 3.5.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 461.0
PYH3_k127_3914254_7 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 407.0
PYH3_k127_3914254_8 Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) K02626 - 4.1.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002861 329.0
PYH3_k127_3914254_9 Alcohol dehydrogenase GroES-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005544 333.0
PYH3_k127_3994700_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 501.0
PYH3_k127_3994700_1 efflux transmembrane transporter activity K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002016 408.0
PYH3_k127_3994700_2 PFAM Iron permease FTR1 - - - 0.000000000000000000000000000000000000000000000000000002688 195.0
PYH3_k127_3994700_3 ABC transporter K02003 - - 0.00000000000000000000000000000000000000004379 153.0
PYH3_k127_4010573_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.0 1005.0
PYH3_k127_4010573_1 Carboxyl transferase domain - - - 6.565e-293 906.0
PYH3_k127_4010573_10 Zinc-uptake complex component A periplasmic K02077 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003479 410.0
PYH3_k127_4010573_11 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009546 405.0
PYH3_k127_4010573_12 ABC 3 transport family K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007022 392.0
PYH3_k127_4010573_13 HMGL-like K01640 - 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 373.0
PYH3_k127_4010573_14 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005328 365.0
PYH3_k127_4010573_15 Enoyl-CoA hydratase/isomerase K13766 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 328.0
PYH3_k127_4010573_16 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 286.0
PYH3_k127_4010573_17 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000113 274.0
PYH3_k127_4010573_18 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002008 269.0
PYH3_k127_4010573_19 Phenazine biosynthesis-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006138 268.0
PYH3_k127_4010573_2 Aromatic amino acid lyase K01745 - 4.3.1.3 9.189e-210 666.0
PYH3_k127_4010573_20 PFAM Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004297 269.0
PYH3_k127_4010573_21 endonuclease III K01247 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000003777 235.0
PYH3_k127_4010573_22 B12 binding domain K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000000000004865 228.0
PYH3_k127_4010573_23 Helix-turn-helix XRE-family like proteins - - - 0.0000000000000000000000000000000000000000000000000000000000002383 216.0
PYH3_k127_4010573_24 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000001967 220.0
PYH3_k127_4010573_25 PFAM thioesterase superfamily K07107 - - 0.000000000000000000000000000000000000000000004712 182.0
PYH3_k127_4010573_26 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000000000000004555 156.0
PYH3_k127_4010573_27 Glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000002614 91.0
PYH3_k127_4010573_28 - - - - 0.000000000000001395 78.0
PYH3_k127_4010573_29 - - - - 0.000000000005162 72.0
PYH3_k127_4010573_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 7.434e-207 649.0
PYH3_k127_4010573_30 PFAM Cysteine-rich secretory protein family - - - 0.00000000001378 74.0
PYH3_k127_4010573_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009683 553.0
PYH3_k127_4010573_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001861 471.0
PYH3_k127_4010573_6 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001548 467.0
PYH3_k127_4010573_7 Peptidase family M50 K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008468 442.0
PYH3_k127_4010573_8 PFAM Pyrrolo-quinoline quinone - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002679 432.0
PYH3_k127_4010573_9 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 431.0
PYH3_k127_4144532_0 PFAM Type II secretion system protein E K02454,K02504,K02652 - - 2.011e-306 948.0
PYH3_k127_4144532_1 signal transduction histidine kinase - - - 2.174e-262 828.0
PYH3_k127_4144532_10 endonuclease III - - - 0.000000000000000000000000000000000000000000000000000000000000001537 229.0
PYH3_k127_4144532_11 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000001974 171.0
PYH3_k127_4144532_12 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000002613 146.0
PYH3_k127_4144532_13 - - - - 0.0000000000000000000000000005215 131.0
PYH3_k127_4144532_14 Class III cytochrome C family - - - 0.000000000005382 74.0
PYH3_k127_4144532_2 Two component, sigma54 specific, transcriptional regulator, Fis family K13599 - - 5.277e-239 747.0
PYH3_k127_4144532_3 Type II/IV secretion system protein K02669 - - 7.807e-198 621.0
PYH3_k127_4144532_4 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 600.0
PYH3_k127_4144532_5 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008033 591.0
PYH3_k127_4144532_6 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004782 452.0
PYH3_k127_4144532_7 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 411.0
PYH3_k127_4144532_8 Two component, sigma54 specific, transcriptional regulator, Fis family K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009291 417.0
PYH3_k127_4144532_9 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 339.0
PYH3_k127_4202865_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.856e-302 933.0
PYH3_k127_4202865_1 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001547 437.0
PYH3_k127_4202865_2 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 406.0
PYH3_k127_4202865_3 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 398.0
PYH3_k127_4202865_4 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001166 376.0
PYH3_k127_4202865_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 320.0
PYH3_k127_4202865_6 Dihydrodipicolinate reductase, C-terminus K00215 - 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001517 265.0
PYH3_k127_4202865_7 Ftsk_gamma K03466 - - 0.000000000000000000000000000000000000000000000000000000000000000002385 233.0
PYH3_k127_4202865_8 Endonuclease containing a URI domain K07461 - - 0.0000000000000000000000000000000009921 134.0
PYH3_k127_4222739_0 ABC transporter, transmembrane K18890 - - 5.88e-290 901.0
PYH3_k127_4222739_1 Bacterial protein of unknown function (DUF885) - - - 9.79e-235 740.0
PYH3_k127_4222739_10 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 331.0
PYH3_k127_4222739_11 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005988 268.0
PYH3_k127_4222739_12 riboflavin synthase, alpha subunit K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000009581 245.0
PYH3_k127_4222739_13 Peptidase family M1 domain - - - 0.00000000000000000000000000000000000000000000000000000000000001362 224.0
PYH3_k127_4222739_14 Lipopolysaccharide-assembly - - - 0.00000000000000000000000000000000000000000000000000000002221 206.0
PYH3_k127_4222739_15 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000000000001815 196.0
PYH3_k127_4222739_17 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000005059 151.0
PYH3_k127_4222739_18 PFAM Peptidase M22, glycoprotease K14742 - - 0.0000000000000000000000000000000000000546 157.0
PYH3_k127_4222739_19 - - - - 0.00000000000000000000000000000001948 142.0
PYH3_k127_4222739_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 1.237e-198 625.0
PYH3_k127_4222739_20 Protein of unknown function (DUF465) - - - 0.00000000000000000001047 93.0
PYH3_k127_4222739_21 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000001194 86.0
PYH3_k127_4222739_3 Beta-ketoacyl synthase, C-terminal domain K09458 - 2.3.1.179 2.741e-198 628.0
PYH3_k127_4222739_4 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 544.0
PYH3_k127_4222739_5 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004348 494.0
PYH3_k127_4222739_6 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 486.0
PYH3_k127_4222739_7 ArgK protein K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008512 439.0
PYH3_k127_4222739_8 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 399.0
PYH3_k127_4222739_9 Semialdehyde dehydrogenase K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 347.0
PYH3_k127_4243917_0 PFAM Cys Met metabolism PLP-dependent enzyme K01739 - 2.5.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001845 494.0
PYH3_k127_4243917_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 431.0
PYH3_k127_4243917_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004466 315.0
PYH3_k127_4243917_3 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000003047 258.0
PYH3_k127_4243917_4 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000001526 216.0
PYH3_k127_4243917_5 AntiSigma factor - - - 0.0000000000000000000000000000000000000000000000000001235 190.0
PYH3_k127_4243917_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000002079 157.0
PYH3_k127_4243917_7 AsmA family K07289 - - 0.0000000000000000000000000000000000007781 154.0
PYH3_k127_4278867_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 1.046e-233 729.0
PYH3_k127_4278867_1 Selenocysteine lyase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000417 578.0
PYH3_k127_4278867_10 Domain in cystathionine beta-synthase and other proteins. K04767 - - 0.00000000000000000007201 95.0
PYH3_k127_4278867_11 Cupredoxin-like domain K02275 - 1.9.3.1 0.00000000000000001216 94.0
PYH3_k127_4278867_12 Enoyl-(Acyl carrier protein) reductase - - - 0.000000001222 59.0
PYH3_k127_4278867_2 Transglycosylase SLT domain K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008126 571.0
PYH3_k127_4278867_3 Belongs to the Glu Leu Phe Val dehydrogenases family K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 518.0
PYH3_k127_4278867_4 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004843 454.0
PYH3_k127_4278867_5 RNA polymerase sigma factor K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001385 284.0
PYH3_k127_4278867_6 nuclear chromosome segregation - - - 0.0000000000000000000000000000000000000000000000000000000002194 216.0
PYH3_k127_4278867_7 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000001763 221.0
PYH3_k127_4278867_8 YceI-like domain - - - 0.000000000000000000000000000000000000000000006078 169.0
PYH3_k127_4278867_9 Putative zinc-finger - - - 0.00000000000000000000001605 111.0
PYH3_k127_4279554_0 Glycosyltransferase family 20 - - - 2.133e-240 764.0
PYH3_k127_4279554_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005188 519.0
PYH3_k127_4279554_10 Regulatory protein, FmdB family - - - 0.0000000000000000002912 89.0
PYH3_k127_4279554_11 Transcriptional regulator PadR-like family - - - 0.000002284 59.0
PYH3_k127_4279554_13 - - - - 0.0008195 42.0
PYH3_k127_4279554_2 Kelch motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001323 334.0
PYH3_k127_4279554_3 Serine aminopeptidase, S33 K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 319.0
PYH3_k127_4279554_4 Beta-lactamase K01286 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000002008 221.0
PYH3_k127_4279554_5 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000000000000001308 197.0
PYH3_k127_4279554_6 Domain of unknown function (DUF4112) - - - 0.0000000000000000000000000000000000000000000000000001519 190.0
PYH3_k127_4279554_7 2'-5' RNA ligase superfamily - - - 0.00000000000000000000000000000000000000000000214 170.0
PYH3_k127_4279554_8 lactoylglutathione lyase activity - - - 0.0000000000000000000000000001601 119.0
PYH3_k127_4279554_9 Pathogenicity locus - - - 0.000000000000000000002762 96.0
PYH3_k127_4283368_0 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1470.0
PYH3_k127_4283368_1 hydrogenase large subunit K14126 - 1.8.98.5 1.669e-235 735.0
PYH3_k127_4283368_10 Belongs to the UPF0276 family - - - 0.000000000000000001588 96.0
PYH3_k127_4283368_11 Catalyzes the SAM-dependent triple methylation of the alpha-amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine K18911 - 2.1.1.44 0.0000000000174 75.0
PYH3_k127_4283368_2 Aldehyde dehydrogenase family - - - 8.368e-203 642.0
PYH3_k127_4283368_3 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 447.0
PYH3_k127_4283368_4 SMART ATPase, AAA type, core K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 309.0
PYH3_k127_4283368_5 Methyl-viologen-reducing hydrogenase, delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000001139 238.0
PYH3_k127_4283368_6 Cytochrome C biogenesis protein transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000003929 233.0
PYH3_k127_4283368_7 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000007183 237.0
PYH3_k127_4283368_8 PFAM Binding-protein-dependent transport system inner membrane component K05846 - - 0.0000000000000000000000000000000000000000000467 164.0
PYH3_k127_4283368_9 Hydrogenase maturation protease K00442 - - 0.0000000000000000000000000000000000001451 147.0
PYH3_k127_4285205_1 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000002279 236.0
PYH3_k127_4285205_2 PFAM Short-chain dehydrogenase reductase SDR K00059,K03793 - 1.1.1.100,1.5.1.33 0.0000000000000000000000000000000000000000000000000000000001963 208.0
PYH3_k127_4285205_3 PFAM Glutaredoxin 2 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000004976 68.0
PYH3_k127_4340017_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004523 610.0
PYH3_k127_4340017_1 Coenzyme A transferase K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 364.0
PYH3_k127_4340017_2 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008843 314.0
PYH3_k127_4340017_3 Coenzyme A transferase K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000004101 205.0
PYH3_k127_4340017_4 Belongs to the TrpF family K01817 - 5.3.1.24 0.00000000000000005955 82.0
PYH3_k127_4344599_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1251.0
PYH3_k127_4344599_1 NeuB family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 536.0
PYH3_k127_4344599_10 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000005457 169.0
PYH3_k127_4344599_11 Endoribonuclease L-PSP - - - 0.000000000000000000000000000006236 124.0
PYH3_k127_4344599_2 von Willebrand factor (vWF) type A domain K07114 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 457.0
PYH3_k127_4344599_3 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 397.0
PYH3_k127_4344599_4 PFAM Uncharacterised conserved protein UCP033563 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 394.0
PYH3_k127_4344599_5 von Willebrand factor, type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002005 376.0
PYH3_k127_4344599_6 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 380.0
PYH3_k127_4344599_7 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005185 362.0
PYH3_k127_4344599_8 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 300.0
PYH3_k127_4344599_9 Biotin-lipoyl like K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000328 292.0
PYH3_k127_4356606_1 heat shock protein binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000009766 244.0
PYH3_k127_4356606_3 ferredoxin-NADP+ reductase activity - - - 0.00000000000000000000000000000000000000000000001156 187.0
PYH3_k127_4427517_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1036.0
PYH3_k127_4427517_1 PFAM Formiminotransferase domain K00603,K13990 - 2.1.2.5,4.3.1.4 7.502e-218 686.0
PYH3_k127_4427517_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000305 160.0
PYH3_k127_4427517_11 Lipid A 3-O-deacylase (PagL) - - - 0.00000000000000000000000000000001969 138.0
PYH3_k127_4427517_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000004885 109.0
PYH3_k127_4427517_13 Heavy-metal resistance - - - 0.0000000000000000000000769 110.0
PYH3_k127_4427517_14 Sporulation related domain - - - 0.000000000000000000001055 100.0
PYH3_k127_4427517_15 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000003374 79.0
PYH3_k127_4427517_2 Aminotransferase class I and II - - - 1.857e-198 625.0
PYH3_k127_4427517_3 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004252 536.0
PYH3_k127_4427517_4 transcriptional regulatory protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008297 397.0
PYH3_k127_4427517_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 370.0
PYH3_k127_4427517_6 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 313.0
PYH3_k127_4427517_7 Oxidoreductase molybdopterin binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002998 287.0
PYH3_k127_4427517_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002008 287.0
PYH3_k127_4427517_9 Glyoxalase-like domain K01759 GO:0008150,GO:0010035,GO:0010038,GO:0042221,GO:0046686,GO:0050896 4.4.1.5 0.0000000000000000000000000000000000000000007562 161.0
PYH3_k127_4473554_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 579.0
PYH3_k127_4473554_1 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000002823 211.0
PYH3_k127_4473554_2 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.00000000006435 64.0
PYH3_k127_457346_0 Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity K03782 - 1.11.1.21 0.0 1284.0
PYH3_k127_457346_1 Prolyl oligopeptidase, N-terminal beta-propeller domain K01322 - 3.4.21.26 7.953e-243 770.0
PYH3_k127_457346_2 Peptidase dimerisation domain - - - 8.894e-208 665.0
PYH3_k127_457346_3 TonB-dependent receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 338.0
PYH3_k127_457346_4 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003359 271.0
PYH3_k127_457346_5 type II secretion system protein K02243,K02652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004201 251.0
PYH3_k127_457346_7 - - - - 0.0000000000000000000000000000003538 132.0
PYH3_k127_457346_8 Vitamin K epoxide reductase - - - 0.00000000000000000000000000003258 124.0
PYH3_k127_457346_9 - - - - 0.00000000000000000000000000003332 137.0
PYH3_k127_4827521_0 hydrolase activity, acting on ester bonds - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 469.0
PYH3_k127_4827521_1 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002365 458.0
PYH3_k127_4827521_2 PFAM NAD-dependent epimerase dehydratase K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 315.0
PYH3_k127_4827521_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002124 289.0
PYH3_k127_4827521_4 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000000003886 239.0
PYH3_k127_4827521_6 Domain of unknown function (DUF4870) - - - 0.000000000000000000008485 97.0
PYH3_k127_4827521_7 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000003287 96.0
PYH3_k127_4827521_8 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000005754 49.0
PYH3_k127_4833171_0 Belongs to the aldehyde dehydrogenase family K00128,K00138 - 1.2.1.3 2.244e-212 670.0
PYH3_k127_4833171_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006419 377.0
PYH3_k127_4833171_2 Dihydrodipicolinate synthetase family K18123 - 4.1.3.16 0.0000000000000000000000000000000000000000000000000000000000005477 218.0
PYH3_k127_4833171_3 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.0000000000000000000000000000000000000000000588 169.0
PYH3_k127_4834408_0 Domain of unknown function (DUF4388) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 347.0
PYH3_k127_4834408_1 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000008403 209.0
PYH3_k127_4834408_2 Probable molybdopterin binding domain - - - 0.000000000000000000001334 97.0
PYH3_k127_4906054_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 7.783e-207 649.0
PYH3_k127_4934178_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1412.0
PYH3_k127_4934178_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 1.907e-297 925.0
PYH3_k127_4934178_10 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002426 241.0
PYH3_k127_4934178_11 CYTH K05873 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000005819 192.0
PYH3_k127_4934178_12 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000000000000000000000004182 160.0
PYH3_k127_4934178_13 - - - - 0.000000000000000000000000000000000000000005834 156.0
PYH3_k127_4934178_14 - - - - 0.00000000000000000000000000000000000001959 154.0
PYH3_k127_4934178_15 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000000000001053 159.0
PYH3_k127_4934178_16 hydroperoxide reductase activity K01607 - 4.1.1.44 0.0000000000000000000000000000003022 124.0
PYH3_k127_4934178_17 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000002097 107.0
PYH3_k127_4934178_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01887 - 6.1.1.19 6.481e-281 876.0
PYH3_k127_4934178_3 Belongs to the GSP D family K02453 - - 1.987e-238 768.0
PYH3_k127_4934178_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 1.194e-195 621.0
PYH3_k127_4934178_5 Protein of unknown function DUF111 K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 511.0
PYH3_k127_4934178_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007394 487.0
PYH3_k127_4934178_7 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007475 458.0
PYH3_k127_4934178_8 TatD related DNase K03424 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 336.0
PYH3_k127_4934178_9 Belongs to the UPF0234 family K09767 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001349 244.0
PYH3_k127_493507_0 Succinate dehydrogenase or fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 376.0
PYH3_k127_493507_1 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 314.0
PYH3_k127_493507_2 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000462 294.0
PYH3_k127_493507_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000001688 201.0
PYH3_k127_493507_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000004832 93.0
PYH3_k127_496900_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 5.305e-308 951.0
PYH3_k127_496900_1 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005351 465.0
PYH3_k127_496900_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004263 443.0
PYH3_k127_496900_3 PFAM DAHP synthetase I K01627 - 2.5.1.55 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002355 392.0
PYH3_k127_496900_4 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000000000006407 107.0
PYH3_k127_496900_5 mRNA binding K07339 - - 0.00000000000000000000001665 102.0
PYH3_k127_496900_7 - - - - 0.0000000001016 70.0
PYH3_k127_4998804_0 Radical SAM - - - 0.0 1163.0
PYH3_k127_4998804_1 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 1.894e-266 841.0
PYH3_k127_4998804_10 PFAM Histidine triad (HIT) protein K02503 - - 0.00000000000000000000000000000000000000000000000000006271 189.0
PYH3_k127_4998804_11 Redoxin - - - 0.000000000000000000000000000000000000000000000000007439 185.0
PYH3_k127_4998804_12 Gram-negative bacterial TonB protein C-terminal - - - 0.0000000000000000000000000000000000000005812 153.0
PYH3_k127_4998804_14 Type II transport protein GspH K08084 - - 0.0000004217 59.0
PYH3_k127_4998804_15 Pilus assembly protein PilX K02673 - - 0.000009829 58.0
PYH3_k127_4998804_2 PA domain - - - 1.691e-230 726.0
PYH3_k127_4998804_3 Amidohydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 610.0
PYH3_k127_4998804_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009448 542.0
PYH3_k127_4998804_5 Cupin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001206 414.0
PYH3_k127_4998804_6 FES K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007027 304.0
PYH3_k127_4998804_7 of the alpha beta superfamily K06889 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005768 290.0
PYH3_k127_4998804_8 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000002479 240.0
PYH3_k127_4998804_9 - - - - 0.000000000000000000000000000000000000000000000000000000006845 203.0
PYH3_k127_5036772_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1279.0
PYH3_k127_5036772_1 Histidine kinase - - - 0.0 1263.0
PYH3_k127_5036772_10 - - - - 0.0000000000008078 72.0
PYH3_k127_5036772_2 response regulator, receiver - - - 1.468e-218 686.0
PYH3_k127_5036772_3 Protein of unknown function DUF58 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000623 557.0
PYH3_k127_5036772_4 Belongs to the MlaE permease family K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009335 384.0
PYH3_k127_5036772_5 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002825 349.0
PYH3_k127_5036772_6 DNA protecting protein DprA K04096 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006251 245.0
PYH3_k127_5036772_7 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000005224 222.0
PYH3_k127_5036772_8 - - - - 0.0000000000000000000000000000001963 129.0
PYH3_k127_5036772_9 BON domain - - - 0.0000000000000000000000151 113.0
PYH3_k127_5089258_0 single-stranded-DNA-specific exonuclease RecJ K07462 - - 8.297e-215 682.0
PYH3_k127_5089258_1 lipopolysaccharide transport K09774 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 627.0
PYH3_k127_5089258_10 Protein of unknown function (DUF507) K09804 - - 0.000000000000000000000000000000001731 139.0
PYH3_k127_5089258_11 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.0000000000000000000000000006376 115.0
PYH3_k127_5089258_12 chaperone-mediated protein folding - - - 0.0000002583 58.0
PYH3_k127_5089258_2 RNA polymerase sigma-54 factor K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 583.0
PYH3_k127_5089258_3 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002192 396.0
PYH3_k127_5089258_4 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002324 405.0
PYH3_k127_5089258_5 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008735 325.0
PYH3_k127_5089258_6 - - - - 0.000000000000000000000000000000000000000000000000000003349 195.0
PYH3_k127_5089258_7 Ribosomal subunit interface protein K05808 - - 0.0000000000000000000000000000000000000000000000006509 196.0
PYH3_k127_5089258_8 COG0666 FOG Ankyrin repeat K06867 - - 0.00000000000000000000000000000000000001386 158.0
PYH3_k127_5089258_9 Plasmid maintenance system killer K07334 - - 0.0000000000000000000000000000000004973 132.0
PYH3_k127_5114495_0 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 489.0
PYH3_k127_5114495_1 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000004391 278.0
PYH3_k127_5114495_2 Domain of unknown function (DUF2520) - - - 0.0000000000000000000000000000000000000004961 154.0
PYH3_k127_5114495_3 - - - - 0.00000000000003023 75.0
PYH3_k127_5114495_4 glycosyl transferase group 1 K00754 - - 0.00001248 47.0
PYH3_k127_5192318_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 8.027e-216 680.0
PYH3_k127_5192318_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K08744 - 2.7.8.41 0.00000000000000000000000000000000000000000000000000000000001619 218.0
PYH3_k127_5192318_2 - - - - 0.0000000000000000000000000009515 118.0
PYH3_k127_5192318_3 PFAM MscS Mechanosensitive ion channel - - - 0.00000000000000001916 94.0
PYH3_k127_5192318_4 Endonuclease containing a URI domain K07461 - - 0.000000008694 59.0
PYH3_k127_5192318_5 PFAM PEGA domain - - - 0.00002451 55.0
PYH3_k127_5195783_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1096.0
PYH3_k127_5195783_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 3.74e-225 703.0
PYH3_k127_5195783_11 - - - - 0.000003179 53.0
PYH3_k127_5195783_2 cyclic nucleotide-binding K01420,K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 319.0
PYH3_k127_5195783_3 Doubled CXXCH motif (Paired_CXXCH_1) K08354 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 319.0
PYH3_k127_5195783_4 Belongs to the arginase family K01480 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 301.0
PYH3_k127_5195783_5 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.000000000000000000000000000000000000000002314 179.0
PYH3_k127_5195783_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.000000000000000000000000000000000002252 139.0
PYH3_k127_5195783_7 EamA-like transporter family K07790 - - 0.00000000000000000000000000000000017 144.0
PYH3_k127_5195783_8 cyclic nucleotide-binding K01420,K10914 - - 0.000000000000000000000000002349 117.0
PYH3_k127_5204422_0 PFAM Type II secretion system protein E K02652 - - 6.968e-281 871.0
PYH3_k127_5204422_1 PFAM Type II secretion system F domain K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000262 456.0
PYH3_k127_5204422_2 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 369.0
PYH3_k127_5204422_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 314.0
PYH3_k127_5204422_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002669 282.0
PYH3_k127_5204422_5 Sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001511 271.0
PYH3_k127_5204422_6 outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004624 248.0
PYH3_k127_5216114_0 PUA-like domain K00958 - 2.7.7.4 2.738e-248 783.0
PYH3_k127_5216114_1 peptidyl-tyrosine sulfation - - - 3.424e-242 767.0
PYH3_k127_5216114_10 belongs to the thioredoxin family K20543 - - 0.0000000000000000001906 104.0
PYH3_k127_5216114_11 - - - - 0.0000001217 55.0
PYH3_k127_5216114_12 domain protein - - - 0.00004186 57.0
PYH3_k127_5216114_2 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.524e-225 724.0
PYH3_k127_5216114_3 peptidyl-tyrosine sulfation - - - 2.613e-208 663.0
PYH3_k127_5216114_4 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 3.262e-203 653.0
PYH3_k127_5216114_5 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 1.86e-202 639.0
PYH3_k127_5216114_6 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 546.0
PYH3_k127_5216114_7 arylsulfatase activity - - - 0.0000000000000000000000000000000000000000000000000000000000004963 223.0
PYH3_k127_5216114_8 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000002094 186.0
PYH3_k127_5216114_9 - - - - 0.00000000000000000000002346 111.0
PYH3_k127_5235100_0 cAMP biosynthetic process K08282,K12132 - 2.7.11.1 1.431e-272 857.0
PYH3_k127_5235100_1 Stage II sporulation protein E K07315 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 530.0
PYH3_k127_5235100_11 Protein of unknown function (DUF3106) - - - 0.000000000000000000008485 97.0
PYH3_k127_5235100_12 - - - - 0.00000000000000000002187 100.0
PYH3_k127_5235100_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008336 505.0
PYH3_k127_5235100_3 Proline dehydrogenase K00318 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007501 424.0
PYH3_k127_5235100_4 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 319.0
PYH3_k127_5235100_5 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001088 269.0
PYH3_k127_5235100_6 Calcineurin-like phosphoesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001325 248.0
PYH3_k127_5235100_7 polyphosphate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000003219 250.0
PYH3_k127_5235100_9 recA bacterial DNA recombination protein - - - 0.000000000000000000000000000000000001439 145.0
PYH3_k127_5249071_0 Malate synthase K01638 - 2.3.3.9 4.09e-235 737.0
PYH3_k127_5249071_1 Phosphoenolpyruvate phosphomutase K01637 - 4.1.3.1 2.667e-205 647.0
PYH3_k127_5249071_2 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002988 314.0
PYH3_k127_5249071_3 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001111 263.0
PYH3_k127_5249071_4 Transcriptional regulator IclR K13641 - - 0.00000000000000000000000000000000000000000000000000000002399 206.0
PYH3_k127_5249071_5 TIGRFAM Caa(3)-type oxidase, subunit IV K02277 - 1.9.3.1 0.000000000000000005415 87.0
PYH3_k127_5249071_7 Belongs to the FPP GGPP synthase family K00805 - 2.5.1.30 0.0000000001161 74.0
PYH3_k127_5339334_0 Protein of unknown function, DUF255 K06888 - - 4.813e-261 815.0
PYH3_k127_5339334_1 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001936 511.0
PYH3_k127_5339334_2 PFAM peptidase K01438 - 3.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004063 449.0
PYH3_k127_5339334_3 Fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 391.0
PYH3_k127_5339334_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004268 359.0
PYH3_k127_5339334_5 Creatinase/Prolidase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 332.0
PYH3_k127_5339334_6 - K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 303.0
PYH3_k127_5352838_0 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0 1579.0
PYH3_k127_5352838_1 4Fe-4S binding domain K00395,K02572,K03616 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000001071 194.0
PYH3_k127_5352838_3 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.00000000002068 67.0
PYH3_k127_5386905_0 COG3119 Arylsulfatase A and related enzymes K01130 - 3.1.6.1 2.015e-301 943.0
PYH3_k127_5386905_1 PFAM Response regulator receiver domain K07713 - - 1.09e-224 725.0
PYH3_k127_5386905_10 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000003905 170.0
PYH3_k127_5386905_11 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000009263 166.0
PYH3_k127_5386905_12 long-chain fatty acid transport protein - - - 0.00000000000000000000000000000000000002396 154.0
PYH3_k127_5386905_13 - - - - 0.0000000000000000000000000000000001488 145.0
PYH3_k127_5386905_14 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000003271 127.0
PYH3_k127_5386905_15 anaerobic respiration - - - 0.00000000000000000000001108 110.0
PYH3_k127_5386905_2 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003227 497.0
PYH3_k127_5386905_3 PFAM Cytochrome c assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 490.0
PYH3_k127_5386905_4 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008689 452.0
PYH3_k127_5386905_5 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 364.0
PYH3_k127_5386905_6 ResB-like family K07399 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 334.0
PYH3_k127_5386905_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 316.0
PYH3_k127_5386905_8 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001436 290.0
PYH3_k127_5386905_9 PFAM NHL repeat containing protein - - - 0.0000000000000000000000000000000000000000000000000000003155 217.0
PYH3_k127_5406068_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003079 484.0
PYH3_k127_5406068_1 chaperone-mediated protein folding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009419 282.0
PYH3_k127_5406068_2 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003903 274.0
PYH3_k127_5406068_3 diguanylate cyclase - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000005798 51.0
PYH3_k127_5415382_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 1.359e-208 655.0
PYH3_k127_5415382_1 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000001022 181.0
PYH3_k127_5415382_2 Modulates RecA activity K03565 - - 0.0000000000000000000000000000000000000000000000002418 181.0
PYH3_k127_5420691_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 531.0
PYH3_k127_5420691_1 amino acid - - - 0.0000000000000000000000000000000000000000000000000000005568 203.0
PYH3_k127_5420691_2 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000000000000000000000001763 185.0
PYH3_k127_5420691_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000001038 132.0
PYH3_k127_5420691_4 Domain of unknown function (DUF4440) - - - 0.00000000000000000000000003145 113.0
PYH3_k127_5433317_0 Beta-Casp domain K07576 - - 6.938e-225 705.0
PYH3_k127_5433317_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 308.0
PYH3_k127_5433317_2 aminopeptidase N - - - 0.0000000000000000000000000000000000000000000002059 172.0
PYH3_k127_5460479_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K07306,K17050 - 1.7.5.1,1.8.5.3 0.0 1449.0
PYH3_k127_5460479_1 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K11177 - 1.17.1.4,1.2.5.3 3.445e-263 844.0
PYH3_k127_5460479_10 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000002322 111.0
PYH3_k127_5460479_11 chaperone-mediated protein complex assembly - - - 0.00000000002247 75.0
PYH3_k127_5460479_2 nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002781 507.0
PYH3_k127_5460479_3 Putative modulator of DNA gyrase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 480.0
PYH3_k127_5460479_4 PFAM molybdopterin dehydrogenase, FAD-binding K03519 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000004361 271.0
PYH3_k127_5460479_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000002595 248.0
PYH3_k127_5460479_6 Ferritin-like domain K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000001273 233.0
PYH3_k127_5460479_7 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000006141 232.0
PYH3_k127_5460479_8 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000002498 192.0
PYH3_k127_5460479_9 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000001656 154.0
PYH3_k127_5461965_0 dead deah K03724 - - 0.0 1976.0
PYH3_k127_5461965_1 Transglycosylase K05365 - 2.4.1.129,3.4.16.4 0.0 1047.0
PYH3_k127_5461965_10 NmrA-like family - - - 0.0000000000000000000000000000000000000000001735 161.0
PYH3_k127_5461965_11 NmrA-like family - - - 0.00000000000000000000000000000000007449 135.0
PYH3_k127_5461965_12 NmrA-like family - - - 0.000000000000000000000000009486 111.0
PYH3_k127_5461965_2 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 2.398e-230 723.0
PYH3_k127_5461965_3 cyclic 2,3-diphosphoglycerate synthetase activity - - - 2.735e-199 629.0
PYH3_k127_5461965_4 Amino acid kinase family K00926 - 2.7.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009235 479.0
PYH3_k127_5461965_5 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003361 465.0
PYH3_k127_5461965_6 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009862 441.0
PYH3_k127_5461965_7 TIGRFAM 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000000000001961 255.0
PYH3_k127_5461965_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000001457 230.0
PYH3_k127_5461965_9 DinB family - - - 0.00000000000000000000000000000000000000000000000000000000188 205.0
PYH3_k127_5467917_0 Aminotransferase, class V - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 547.0
PYH3_k127_5467917_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 372.0
PYH3_k127_5467917_2 Calcineurin-like phosphoesterase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 297.0
PYH3_k127_5467917_4 Reverse transcriptase-like K03469 - 3.1.26.4 0.00000000000000000000000000000000000000000000000000000008944 201.0
PYH3_k127_5467917_5 Yqey-like protein K09117 - - 0.000000000000000000000000000000000000000000000002203 177.0
PYH3_k127_5609371_0 Putative modulator of DNA gyrase K03568 - - 1.866e-237 777.0
PYH3_k127_5609371_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 1.791e-228 713.0
PYH3_k127_5609371_2 Sulfate permease family K03321 - - 1.326e-221 700.0
PYH3_k127_5609371_3 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 8.484e-200 631.0
PYH3_k127_5609371_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 537.0
PYH3_k127_5609371_5 Mycothiol maleylpyruvate isomerase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001735 237.0
PYH3_k127_5609371_6 Putative modulator of DNA gyrase - - - 0.0000000000000000000000000004665 116.0
PYH3_k127_5609371_7 - - - - 0.00000000000000000000001878 103.0
PYH3_k127_5682973_0 HELICc2 K03722 - 3.6.4.12 1.797e-270 847.0
PYH3_k127_5682973_1 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 357.0
PYH3_k127_5682973_2 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001245 252.0
PYH3_k127_5682973_3 PFAM 6-pyruvoyl tetrahydropterin K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000000000000000000000000000003051 201.0
PYH3_k127_5682973_4 23S rRNA-intervening sequence protein - - - 0.0000000000000000000000000009764 117.0
PYH3_k127_5682973_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000002957 80.0
PYH3_k127_5760322_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 516.0
PYH3_k127_5760322_1 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007018 481.0
PYH3_k127_5760322_2 SMART band 7 protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 374.0
PYH3_k127_5760322_3 Sporulation related domain - - - 0.000002884 50.0
PYH3_k127_5806179_0 Asparagine synthase K01953 - 6.3.5.4 1.656e-264 836.0
PYH3_k127_5806179_1 Peptidase M56 - - - 1.382e-225 712.0
PYH3_k127_5806179_10 Ornithine cyclodeaminase/mu-crystallin family K01750,K18258 - 1.5.1.25,4.3.1.12 0.000000000000000000000000000000000000000000000000000000001667 211.0
PYH3_k127_5806179_11 Protein of unknown function (DUF421) - - - 0.0000000000000000000000000000000000000000000000000008251 193.0
PYH3_k127_5806179_12 - - - - 0.00000000000000000000000000000000000000001062 160.0
PYH3_k127_5806179_13 DNA integration - - - 0.000000000000000000000000000002209 127.0
PYH3_k127_5806179_14 Calcineurin-like phosphoesterase - - - 0.000000000000000000003254 102.0
PYH3_k127_5806179_15 energy transducer activity K03832 - - 0.00002519 56.0
PYH3_k127_5806179_2 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 538.0
PYH3_k127_5806179_3 Efflux transporter, RND family, MFP subunit K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 493.0
PYH3_k127_5806179_4 penicillin-binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001109 452.0
PYH3_k127_5806179_5 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 468.0
PYH3_k127_5806179_6 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 426.0
PYH3_k127_5806179_7 ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 394.0
PYH3_k127_5806179_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 364.0
PYH3_k127_5806179_9 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000001516 228.0
PYH3_k127_5987935_0 Beta-Casp domain K07576 - - 3.069e-224 705.0
PYH3_k127_5987935_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.00002083 47.0
PYH3_k127_607294_0 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 - 1.1.1.42 1.635e-247 769.0
PYH3_k127_607294_1 PFAM Radical SAM - - - 2.384e-229 720.0
PYH3_k127_607294_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 530.0
PYH3_k127_607294_3 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 311.0
PYH3_k127_607294_4 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000006708 256.0
PYH3_k127_607294_5 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.00000000000000000000000000000000000000003791 170.0
PYH3_k127_6182510_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.574e-202 638.0
PYH3_k127_6182510_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 449.0
PYH3_k127_6182510_2 signal sequence binding K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004914 259.0
PYH3_k127_6212665_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002539 462.0
PYH3_k127_6212665_1 peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001238 323.0
PYH3_k127_6212665_2 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000005035 182.0
PYH3_k127_6212665_3 tetraacyldisaccharide 4'-kinase activity K00912,K09791 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 2.7.1.130 0.000000000000006001 75.0
PYH3_k127_6212665_4 TIGRFAM RHS repeat-associated core domain - - - 0.00000001694 64.0
PYH3_k127_6223963_0 metalloendopeptidase activity K01283 - 3.4.15.1 3.118e-262 820.0
PYH3_k127_6223963_1 FMN binding K00104,K16422 - 1.1.3.15,1.1.3.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005146 418.0
PYH3_k127_6223963_10 PBS lyase HEAT domain protein repeat-containing protein - - - 0.00005288 55.0
PYH3_k127_6223963_11 PFAM thiamine monophosphate synthase K00788 - 2.5.1.3 0.0001668 44.0
PYH3_k127_6223963_2 UPF0210 protein K09157 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007865 418.0
PYH3_k127_6223963_3 Domain of unknown function (DUF1905) - - - 0.000000000000000000000000000000000000000000001292 173.0
PYH3_k127_6223963_4 COG NOG14600 non supervised orthologous group - - - 0.0000000000000000000000000000000000007694 140.0
PYH3_k127_6223963_5 PFAM pyridoxamine 5'-phosphate oxidase-related, FMN-binding K07006 - - 0.00000000000000000000008083 107.0
PYH3_k127_6223963_7 Transposase IS200 like K07491 - - 0.0000000000000000000003931 101.0
PYH3_k127_6249576_0 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 393.0
PYH3_k127_6249576_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007997 371.0
PYH3_k127_6249576_2 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 298.0
PYH3_k127_6249576_3 Beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005841 266.0
PYH3_k127_6249576_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000002908 228.0
PYH3_k127_6249576_5 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase - - - 0.000000000000000000114 93.0
PYH3_k127_6249576_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.00000000000000003132 88.0
PYH3_k127_6249576_7 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III K00648 - 2.3.1.180 0.0000000000000003881 90.0
PYH3_k127_6250568_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 3.117e-257 803.0
PYH3_k127_6250568_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 4.97e-217 680.0
PYH3_k127_6250568_10 synthase K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000028 219.0
PYH3_k127_6250568_12 - - - - 0.000000000000000002208 94.0
PYH3_k127_6250568_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 589.0
PYH3_k127_6250568_3 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 413.0
PYH3_k127_6250568_4 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001162 366.0
PYH3_k127_6250568_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001764 359.0
PYH3_k127_6250568_6 PFAM Chlorite dismutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001952 357.0
PYH3_k127_6250568_7 Cytochrome C assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007803 338.0
PYH3_k127_6250568_8 Fungal family of unknown function (DUF1776) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005837 301.0
PYH3_k127_6250568_9 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009715 282.0
PYH3_k127_6273885_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.204e-308 957.0
PYH3_k127_6273885_1 Ribosomal protein S1 K02945 - - 6.265e-248 780.0
PYH3_k127_6273885_2 Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K00567,K10778 - 2.1.1.63 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 392.0
PYH3_k127_6273885_3 PFAM Histidine triad (HIT) protein K19710 - 2.7.7.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000002638 262.0
PYH3_k127_6273885_5 Carboxypeptidase regulatory-like domain - - - 0.00000000000000000005728 96.0
PYH3_k127_6273885_6 - K05826 - - 0.0000000000005755 71.0
PYH3_k127_6273885_7 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000005275 66.0
PYH3_k127_6273885_8 Diacylglycerol kinase catalytic domain (presumed) - - - 0.00000958 53.0
PYH3_k127_6273885_9 Patatin-like phospholipase K07001 - - 0.00001809 57.0
PYH3_k127_6282983_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1734.0
PYH3_k127_6282983_1 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000483 614.0
PYH3_k127_6282983_2 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002009 576.0
PYH3_k127_6282983_3 Virulence factor BrkB K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003292 312.0
PYH3_k127_6282983_4 CDP-alcohol phosphatidyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005905 263.0
PYH3_k127_6282983_5 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001301 252.0
PYH3_k127_6282983_6 (Rhomboid) family - - - 0.00000000000000000000000000000000000000000000000000000000000000009027 231.0
PYH3_k127_6282983_7 GtrA-like protein - - - 0.00000000000000000000000000000001985 136.0
PYH3_k127_639157_0 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 1.208e-239 748.0
PYH3_k127_639157_1 PFAM peptidase U62 modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 609.0
PYH3_k127_639157_10 Cytochrome oxidase complex assembly protein 1 - - - 0.000000000000000000000000000000001015 140.0
PYH3_k127_639157_11 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000000000000003404 108.0
PYH3_k127_639157_12 - - - - 0.000000000000000000006871 104.0
PYH3_k127_639157_2 Protein of unknown function (DUF1343) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003299 584.0
PYH3_k127_639157_3 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007867 571.0
PYH3_k127_639157_4 PFAM peptidase U62 modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001994 419.0
PYH3_k127_639157_5 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005619 363.0
PYH3_k127_639157_6 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000005193 266.0
PYH3_k127_639157_7 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
PYH3_k127_639157_8 FecR protein - - - 0.00000000000000000000000000000000000000000000000000000000000007703 237.0
PYH3_k127_639157_9 BadF/BadG/BcrA/BcrD ATPase family - - - 0.00000000000000000000000000000000000000000000009812 179.0
PYH3_k127_6423759_0 peptidase K07386 - - 4.001e-280 881.0
PYH3_k127_6423759_1 Permease family K06901 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 578.0
PYH3_k127_6423759_2 Rhodanese-like domain K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004324 506.0
PYH3_k127_6423759_3 iron ion homeostasis K05349 - 3.2.1.21 0.00000000000000000000005937 108.0
PYH3_k127_6423759_4 PFAM FecR protein - - - 0.000000006255 69.0
PYH3_k127_6423938_0 TonB dependent receptor - - - 0.0 1044.0
PYH3_k127_6423938_1 Lysin motif K08307 - - 1.534e-213 701.0
PYH3_k127_6423938_10 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000000000000085 207.0
PYH3_k127_6423938_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000004791 198.0
PYH3_k127_6423938_12 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0000000000000000000000000000000000000000000000000000553 190.0
PYH3_k127_6423938_13 Likely ribonuclease with RNase H fold. K07447 - - 0.000000000000000000000000000000000000000000000001044 179.0
PYH3_k127_6423938_14 - - - - 0.00000000000000000000000000002009 126.0
PYH3_k127_6423938_15 - K21449 - - 0.0000000000000000000000001195 112.0
PYH3_k127_6423938_16 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.00000000000000000001046 92.0
PYH3_k127_6423938_2 lipoprotein localization to outer membrane K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001623 441.0
PYH3_k127_6423938_3 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005778 418.0
PYH3_k127_6423938_4 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001293 407.0
PYH3_k127_6423938_5 e3 binding domain K00658 - 2.3.1.61 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002616 301.0
PYH3_k127_6423938_6 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003918 273.0
PYH3_k127_6423938_7 CarD-like/TRCF domain K07736 - - 0.0000000000000000000000000000000000000000000000000000000000000000001524 233.0
PYH3_k127_6423938_8 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000001576 228.0
PYH3_k127_6423938_9 phosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000009437 216.0
PYH3_k127_6489326_0 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.0 1061.0
PYH3_k127_6489326_1 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL K07303 - 1.3.99.16 2.012e-242 769.0
PYH3_k127_6489326_10 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004229 471.0
PYH3_k127_6489326_11 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 436.0
PYH3_k127_6489326_12 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007751 421.0
PYH3_k127_6489326_13 slime layer polysaccharide biosynthetic process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 427.0
PYH3_k127_6489326_14 amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004629 411.0
PYH3_k127_6489326_15 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 367.0
PYH3_k127_6489326_16 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004759 344.0
PYH3_k127_6489326_17 Provides the (R)-glutamate required for cell wall biosynthesis K01776 - 5.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004418 318.0
PYH3_k127_6489326_18 alpha/beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004997 308.0
PYH3_k127_6489326_19 Male sterility protein K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 322.0
PYH3_k127_6489326_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 3.051e-242 759.0
PYH3_k127_6489326_20 Male sterility protein K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001165 290.0
PYH3_k127_6489326_21 PA domain K01342,K14645 - 3.4.21.62 0.0000000000000000000000000000000000000000000000000000000000000000000000001129 260.0
PYH3_k127_6489326_22 Bacterial regulatory proteins, tetR family K13770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003568 249.0
PYH3_k127_6489326_23 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002158 249.0
PYH3_k127_6489326_24 COG1404 Subtilisin-like serine proteases - - - 0.00000000000000000000000000000000000000000000000000000000000000000003117 240.0
PYH3_k127_6489326_25 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000001911 259.0
PYH3_k127_6489326_26 tRNA m6t6A37 methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000004809 230.0
PYH3_k127_6489326_27 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000005239 234.0
PYH3_k127_6489326_28 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.000000000000000000000000000000000000000000000000000000004272 203.0
PYH3_k127_6489326_29 PFAM cell wall hydrolase autolysin K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000003761 193.0
PYH3_k127_6489326_3 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III - - - 1.743e-221 694.0
PYH3_k127_6489326_30 PFAM YbaK prolyl-tRNA synthetase associated region K19055 - - 0.00000000000000000000000000000000000000000000000000004447 193.0
PYH3_k127_6489326_31 Sporulation and spore germination - - - 0.000000000000000000000000000000000000000000001565 175.0
PYH3_k127_6489326_32 RibD C-terminal domain - - - 0.00000000000000000000000000000000000000000382 170.0
PYH3_k127_6489326_33 peroxiredoxin activity K01607 - 4.1.1.44 0.00000000000000000000000000000000001499 139.0
PYH3_k127_6489326_34 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000005309 144.0
PYH3_k127_6489326_35 PspC domain K03973 - - 0.0000000000000000000000000000000001297 136.0
PYH3_k127_6489326_36 - - - - 0.0000000000000000000000000000000002406 136.0
PYH3_k127_6489326_38 OsmC-like protein - - - 0.000000000000000000000000000001051 126.0
PYH3_k127_6489326_39 CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000001143 120.0
PYH3_k127_6489326_4 AMP-binding enzyme K01897 - 6.2.1.3 1.826e-214 682.0
PYH3_k127_6489326_40 PFAM NAD-dependent epimerase dehydratase - - - 0.00000000000000000000000001488 126.0
PYH3_k127_6489326_41 PFAM Septum formation initiator K05589 - - 0.000000000000000000001095 101.0
PYH3_k127_6489326_42 haloacid dehalogenase-like hydrolase - - - 0.0000000000000007763 92.0
PYH3_k127_6489326_43 peroxiredoxin activity K03564 - 1.11.1.15 0.00000000000009752 75.0
PYH3_k127_6489326_44 - - - - 0.000000002863 58.0
PYH3_k127_6489326_45 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000003385 57.0
PYH3_k127_6489326_46 Redoxin K03386 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009605,GO:0009607,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0020012,GO:0030682,GO:0042221,GO:0043207,GO:0044403,GO:0044413,GO:0044415,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0050896,GO:0051409,GO:0051701,GO:0051704,GO:0051707,GO:0051716,GO:0051805,GO:0051807,GO:0051832,GO:0051834,GO:0051920,GO:0052060,GO:0052173,GO:0052200,GO:0052376,GO:0052551,GO:0052564,GO:0052565,GO:0052572,GO:0055114,GO:0070887,GO:0075136,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0000007004 55.0
PYH3_k127_6489326_47 Thermolysin metallopeptidase, alpha-helical domain - - - 0.00001813 56.0
PYH3_k127_6489326_48 - - - - 0.00006038 51.0
PYH3_k127_6489326_5 Belongs to the citrate synthase family K01647 - 2.3.3.1 9.745e-212 664.0
PYH3_k127_6489326_6 Sulfatase - - - 4.715e-211 667.0
PYH3_k127_6489326_7 Cys/Met metabolism PLP-dependent enzyme K01760,K17217 - 4.4.1.1,4.4.1.2,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004008 568.0
PYH3_k127_6489326_8 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K15372 - 2.6.1.19,2.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000209 565.0
PYH3_k127_6489326_9 PFAM deoxyribose-phosphate aldolase phospho-2-dehydro-3-deoxyheptonate aldolase K01635 - 4.1.2.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 507.0
PYH3_k127_6605705_0 PFAM natural resistance-associated macrophage protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006544 571.0
PYH3_k127_6605705_1 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001378 479.0
PYH3_k127_6605705_10 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.00000000000000000000000000000000000000000000000000000002413 202.0
PYH3_k127_6605705_11 Histidine kinase-like ATPase domain K04757 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000003898 192.0
PYH3_k127_6605705_12 NUDIX domain K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000003097 163.0
PYH3_k127_6605705_13 methyltransferase activity - - - 0.000000000000000000000000000000000000001438 153.0
PYH3_k127_6605705_14 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000002425 142.0
PYH3_k127_6605705_15 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000006543 131.0
PYH3_k127_6605705_16 - - - - 0.000000000000000000000000000000174 131.0
PYH3_k127_6605705_17 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000003771 124.0
PYH3_k127_6605705_18 PFAM Forkhead-associated protein - - - 0.0006664 49.0
PYH3_k127_6605705_2 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002397 484.0
PYH3_k127_6605705_3 MgtE intracellular N domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 470.0
PYH3_k127_6605705_4 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 437.0
PYH3_k127_6605705_5 XdhC and CoxI family K07402 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 406.0
PYH3_k127_6605705_6 GHMP kinases C terminal K07031 - 2.7.1.168 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004893 389.0
PYH3_k127_6605705_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 301.0
PYH3_k127_6605705_8 Radical SAM superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005355 293.0
PYH3_k127_6605705_9 MobA-Related Protein K07141,K19190 - 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000000000000000000000000000000003398 246.0
PYH3_k127_6723027_0 GTP-binding protein TypA K06207 - - 1.542e-315 974.0
PYH3_k127_6723027_1 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 1.155e-253 809.0
PYH3_k127_6723027_2 AMMECR1 K06990,K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 495.0
PYH3_k127_6723027_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 452.0
PYH3_k127_6723027_4 Regulates arginine biosynthesis genes K03402 - - 0.00000000000000000000000000000000000000000009652 163.0
PYH3_k127_6723027_5 STAS domain K04749 - - 0.00000000000000000000000466 105.0
PYH3_k127_6723027_6 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000002298 76.0
PYH3_k127_6744820_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 592.0
PYH3_k127_6744820_1 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 579.0
PYH3_k127_6744820_2 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.000000000000000000000000000000164 126.0
PYH3_k127_6854291_0 Dipeptidyl peptidase IV (DPP IV) N-terminal region K01278 - 3.4.14.5 1.524e-258 827.0
PYH3_k127_6854291_1 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003333 459.0
PYH3_k127_6854291_2 Domain of unknown function (DUF4382) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 452.0
PYH3_k127_6854291_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 374.0
PYH3_k127_6854291_4 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 340.0
PYH3_k127_6854291_5 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 352.0
PYH3_k127_6854291_6 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000005868 219.0
PYH3_k127_6854291_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000000000000000000000000000663 203.0
PYH3_k127_6854291_8 Regulatory protein, FmdB - - - 0.0000000000000000000000002383 108.0
PYH3_k127_6854291_9 Tetratricopeptide repeat - - - 0.000007028 58.0
PYH3_k127_6916564_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1057.0
PYH3_k127_6916564_1 PFAM Major facilitator superfamily K08178 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006002 533.0
PYH3_k127_6916564_2 Protein of unknown function (DUF1624) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004716 391.0
PYH3_k127_6916564_3 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 347.0
PYH3_k127_6916564_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 315.0
PYH3_k127_6916564_5 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005252 251.0
PYH3_k127_6916564_6 - - - - 0.000000000000000000000000000007691 126.0
PYH3_k127_6967881_0 PEP-utilising enzyme, mobile domain K01006 - 2.7.9.1 0.0 1378.0
PYH3_k127_6967881_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 8.776e-199 633.0
PYH3_k127_6967881_2 PD-(D/E)XK nuclease superfamily - - - 0.00000000000000000000000000000006207 126.0
PYH3_k127_6967881_3 Belongs to the anti-sigma-factor antagonist family K04749 - - 0.0000000000004052 74.0
PYH3_k127_6967881_4 PD-(D/E)XK nuclease superfamily - - - 0.000005754 49.0
PYH3_k127_7169827_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1113.0
PYH3_k127_7169827_1 Dehydrogenase E1 component K11381 - 1.2.4.4 0.0 1097.0
PYH3_k127_7169827_10 Oxidoreductase - - - 0.000000000001245 73.0
PYH3_k127_7169827_2 Flavin containing amine oxidoreductase - - - 6.125e-300 925.0
PYH3_k127_7169827_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.982e-195 624.0
PYH3_k127_7169827_4 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 572.0
PYH3_k127_7169827_5 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001765 368.0
PYH3_k127_7169827_6 HAD-hyrolase-like K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005077 293.0
PYH3_k127_7169827_7 Belongs to the aspartate glutamate racemases family K01779 - 5.1.1.13 0.000000000000000000000000000000000000000000000000000000000000008513 225.0
PYH3_k127_7169827_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000682 219.0
PYH3_k127_7169827_9 DoxX K15977 - - 0.00000000000000000000000000001872 123.0
PYH3_k127_7191753_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1095.0
PYH3_k127_7191753_1 PFAM UvrD REP helicase K03657 - 3.6.4.12 0.0 1085.0
PYH3_k127_7191753_10 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000001294 188.0
PYH3_k127_7191753_11 Isochorismate synthase K02552 - 5.4.4.2 0.0000000000000000000000000000000000000000000009812 173.0
PYH3_k127_7191753_12 PFAM Endoribonuclease L-PSP K09022 - 3.5.99.10 0.000000000000000000000000000000000000000001588 162.0
PYH3_k127_7191753_13 TonB dependent receptor K16087 - - 0.0000000000000000000000000000000000002185 162.0
PYH3_k127_7191753_14 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000001395 109.0
PYH3_k127_7191753_15 response to heat K07090 - - 0.00000000000000000000000001573 113.0
PYH3_k127_7191753_16 - - - - 0.0000000000000002394 87.0
PYH3_k127_7191753_2 amino acid K03294 - - 7.881e-232 727.0
PYH3_k127_7191753_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 5.64e-217 683.0
PYH3_k127_7191753_4 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005317 507.0
PYH3_k127_7191753_5 Adenosine/AMP deaminase K01488,K18286 - 3.5.4.4,3.5.4.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001205 386.0
PYH3_k127_7191753_6 Domain of unknown function (DUF1731) K07071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 335.0
PYH3_k127_7191753_7 ABC transporter K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007259 316.0
PYH3_k127_7191753_8 Amidohydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 309.0
PYH3_k127_7191753_9 Yip1 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002421 267.0
PYH3_k127_7219546_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 1.936e-222 696.0
PYH3_k127_7219546_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009297 464.0
PYH3_k127_7219546_10 amino acid - - - 0.000000000000000000000000003609 117.0
PYH3_k127_7219546_11 Belongs to the UPF0109 family K06960 - - 0.00000000000000000000000002416 109.0
PYH3_k127_7219546_12 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000006282 67.0
PYH3_k127_7219546_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 388.0
PYH3_k127_7219546_3 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 373.0
PYH3_k127_7219546_4 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000131 240.0
PYH3_k127_7219546_5 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000001148 212.0
PYH3_k127_7219546_6 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000000000000000000009405 197.0
PYH3_k127_7219546_7 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000005991 183.0
PYH3_k127_7219546_8 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.0000000000000000000000000000004559 124.0
PYH3_k127_7219546_9 transcriptional regulator - - - 0.000000000000000000000000000004995 130.0
PYH3_k127_7270038_0 pfam abc K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 502.0
PYH3_k127_7270038_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 489.0
PYH3_k127_7270038_10 Ribosomal L32p protein family K02911 - - 0.000000000000000000000000001618 112.0
PYH3_k127_7270038_11 PFAM ABC transporter related K01990,K16907 - - 0.000000000000000004379 88.0
PYH3_k127_7270038_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 440.0
PYH3_k127_7270038_3 malonyl CoA-acyl carrier protein transacylase K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001095 404.0
PYH3_k127_7270038_4 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 319.0
PYH3_k127_7270038_5 Biotin-lipoyl like K01993 - - 0.000000000000000000000000000000000000000000000000000000000000003536 225.0
PYH3_k127_7270038_6 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000000000000000000000000000000000000000000002402 205.0
PYH3_k127_7270038_7 - - - - 0.000000000000000000000000000000000000000000000133 172.0
PYH3_k127_7270038_8 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.0000000000000000000000000000000000000000004454 166.0
PYH3_k127_7270038_9 Pfam:N_methyl_2 - - - 0.0000000000000000000000000000000000000001015 155.0
PYH3_k127_7315709_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.031e-271 845.0
PYH3_k127_7315709_1 Cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000002432 192.0
PYH3_k127_7315709_2 Calcineurin-like phosphoesterase K07098 - - 0.000000000000000000000000000000000000000000000006272 192.0
PYH3_k127_7315709_3 PFAM cytochrome c oxidase subunit III K02276 - 1.9.3.1 0.000000000000000000000000000000000000000001016 163.0
PYH3_k127_7324351_0 Sodium Bile acid symporter family K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 518.0
PYH3_k127_7324351_1 Belongs to the PstS family K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004213 488.0
PYH3_k127_7324351_10 - - - - 0.0000000000000000000000000000000000000000000000000002125 206.0
PYH3_k127_7324351_11 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000001056 154.0
PYH3_k127_7324351_2 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001335 387.0
PYH3_k127_7324351_3 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007212 361.0
PYH3_k127_7324351_4 Phosphate transport system permease protein PstA K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007156 370.0
PYH3_k127_7324351_5 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 344.0
PYH3_k127_7324351_6 Histidine kinase K07636 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001816 334.0
PYH3_k127_7324351_7 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008298 289.0
PYH3_k127_7324351_8 negative regulation of phosphate transmembrane transport K02039 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009892,GO:0010563,GO:0010966,GO:0019220,GO:0019222,GO:0031323,GO:0031324,GO:0032879,GO:0034762,GO:0034763,GO:0034765,GO:0034766,GO:0042802,GO:0042803,GO:0043269,GO:0043271,GO:0044070,GO:0044424,GO:0044464,GO:0045936,GO:0046983,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051049,GO:0051051,GO:0051174,GO:0065007,GO:1903792,GO:1903795,GO:1903796,GO:1903959,GO:1903960,GO:2000185,GO:2000186 - 0.0000000000000000000000000000000000000000000000000000000002093 211.0
PYH3_k127_7324351_9 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000006033 192.0
PYH3_k127_735547_0 Glycogen debranching enzyme - - - 0.0 1468.0
PYH3_k127_735547_1 Alpha amylase, catalytic domain - - - 2.148e-235 737.0
PYH3_k127_735547_11 PFAM GYD family protein - - - 0.000000000000001636 79.0
PYH3_k127_735547_12 - - - - 0.000000000000004172 83.0
PYH3_k127_735547_2 regulation of DNA-templated transcription, elongation - - - 7.985e-232 751.0
PYH3_k127_735547_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 402.0
PYH3_k127_735547_4 Protein of unknown function (DUF2950) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 399.0
PYH3_k127_735547_5 VIT family - - - 0.00000000000000000000000000000000000000000000000000000000000002806 221.0
PYH3_k127_735547_6 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000003343 162.0
PYH3_k127_735547_7 Disulphide bond corrector protein DsbC K04084 - 1.8.1.8 0.0000000000000000000000000000000000000217 150.0
PYH3_k127_735547_8 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000001803 151.0
PYH3_k127_735547_9 - - - - 0.00000000000000000000000000009708 123.0
PYH3_k127_7356155_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1255.0
PYH3_k127_7356155_1 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 1.314e-244 775.0
PYH3_k127_7356155_10 MoaE protein K21142 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000004898 270.0
PYH3_k127_7356155_11 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000006414 248.0
PYH3_k127_7356155_12 4Fe-4S dicluster domain K05524 - - 0.000000000000000000000000000000000000000000000001539 174.0
PYH3_k127_7356155_14 FR47-like protein K03789 - 2.3.1.128 0.000000000000000000000000000005448 126.0
PYH3_k127_7356155_15 Hfq protein K03666 - - 0.000000000000000000000000001066 113.0
PYH3_k127_7356155_16 Pfam:N_methyl_2 - - - 0.00000000000002752 74.0
PYH3_k127_7356155_2 3-isopropylmalate dehydratase activity K01681,K01703,K01704,K17749 - 4.2.1.3,4.2.1.33,4.2.1.35 6.218e-233 741.0
PYH3_k127_7356155_3 Belongs to the peptidase M16 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005078 592.0
PYH3_k127_7356155_4 Peptidase dimerisation domain K12941 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 515.0
PYH3_k127_7356155_5 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 475.0
PYH3_k127_7356155_6 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003125 423.0
PYH3_k127_7356155_7 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004106 415.0
PYH3_k127_7356155_8 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001738 353.0
PYH3_k127_7356155_9 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001484 348.0
PYH3_k127_7369573_0 aminoacyl-tRNA synthetase K01867 - 6.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 542.0
PYH3_k127_7369573_1 Aminotransferase class-V K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 436.0
PYH3_k127_7369573_2 ROK family K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 376.0
PYH3_k127_7369573_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 354.0
PYH3_k127_7369573_4 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 339.0
PYH3_k127_7369573_5 maltose O-acetyltransferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001056 320.0
PYH3_k127_7369573_6 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.0000000000000000000000000000000000000000000000000000000000001225 223.0
PYH3_k127_7369573_7 PFAM peptidase - - - 0.0000000000000000000000000000000000000000000000000000000000004841 218.0
PYH3_k127_7369573_8 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000346 211.0
PYH3_k127_7369573_9 AsmA family K07289 - - 0.0000000000009285 72.0
PYH3_k127_7421646_0 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 2.07e-226 705.0
PYH3_k127_7421646_1 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 557.0
PYH3_k127_7421646_10 - - - - 0.0000000000000003545 87.0
PYH3_k127_7421646_11 Predicted membrane protein (DUF2085) - - - 0.000000004214 63.0
PYH3_k127_7421646_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000989 528.0
PYH3_k127_7421646_3 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 374.0
PYH3_k127_7421646_4 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000001537 245.0
PYH3_k127_7421646_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000001663 196.0
PYH3_k127_7421646_6 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000003896 104.0
PYH3_k127_7421646_8 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000005042 94.0
PYH3_k127_7421646_9 - - - - 0.00000000000000000002639 99.0
PYH3_k127_744280_0 virulence factor MVIN family protein K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 614.0
PYH3_k127_744280_1 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000466 289.0
PYH3_k127_744280_2 aminopeptidase activity K07004 - - 0.0000000000000000000000000000000000000000000000006729 201.0
PYH3_k127_744280_3 Periplasmic or secreted lipoprotein - - - 0.00000000602 57.0
PYH3_k127_7450001_0 Peptidase M16 inactive domain K07263 - - 6.481e-247 785.0
PYH3_k127_7450001_1 FAD dependent oxidoreductase K00303,K21061 - 1.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002789 593.0
PYH3_k127_7450001_10 MASE1 - - - 0.00000000000000000000000000000000000000000000000000000000000000005802 241.0
PYH3_k127_7450001_11 Domain of unknown function (DUF4870) K09940 - - 0.0000000000000000000000000000000363 132.0
PYH3_k127_7450001_12 Domain of unknown function (DUF4870) K09940 - - 0.00000000000000000000000008212 113.0
PYH3_k127_7450001_13 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000002806 112.0
PYH3_k127_7450001_2 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005335 607.0
PYH3_k127_7450001_3 CoA-binding K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 486.0
PYH3_k127_7450001_4 metalloendopeptidase activity K01283 - 3.4.15.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 484.0
PYH3_k127_7450001_5 oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009632 412.0
PYH3_k127_7450001_6 Belongs to the 'phage' integrase family. XerC subfamily K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002944 395.0
PYH3_k127_7450001_7 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 369.0
PYH3_k127_7450001_8 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K03778,K18347 - 1.1.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002615 354.0
PYH3_k127_7450001_9 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001864 245.0
PYH3_k127_7504522_0 Bacterial regulatory protein, Fis family - - - 6.724e-199 628.0
PYH3_k127_7504522_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 480.0
PYH3_k127_7504522_10 Protein of unknown function (DUF1569) - - - 0.000000000000000000000000008169 117.0
PYH3_k127_7504522_11 Reverse transcriptase-like K03469 - 3.1.26.4 0.0000000000000000000000003681 109.0
PYH3_k127_7504522_12 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000002782 109.0
PYH3_k127_7504522_13 BadF BadG BcrA BcrD type - - - 0.0008316 44.0
PYH3_k127_7504522_2 Histidine kinase K02668,K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 441.0
PYH3_k127_7504522_3 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002833 409.0
PYH3_k127_7504522_4 Bacterial Peptidase A24 N-terminal domain K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007536 317.0
PYH3_k127_7504522_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000001309 228.0
PYH3_k127_7504522_7 - - - - 0.000000000000000000000000000000000000000000000000000000008539 208.0
PYH3_k127_7504522_8 Glycosyl transferase, family 2 - - - 0.000000000000000000000000000000000007507 143.0
PYH3_k127_7541918_0 AAA ATPase K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 570.0
PYH3_k127_7541918_1 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 325.0
PYH3_k127_7541918_2 Belongs to the SUA5 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 286.0
PYH3_k127_7541918_3 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000001707 230.0
PYH3_k127_7541918_4 Putative cyclase - - - 0.000000000000000000000000000000000000001205 150.0
PYH3_k127_7565291_0 Aminotransferase class-V K01556 - 3.7.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 443.0
PYH3_k127_7565291_1 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003107 299.0
PYH3_k127_7565291_2 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000004465 166.0
PYH3_k127_7565291_3 Amino acid permease - - - 0.0000000004025 65.0
PYH3_k127_7565291_4 - - - - 0.000000008323 63.0
PYH3_k127_7577052_0 Penicillin-binding protein, dimerisation domain K03587 - 3.4.16.4 9.863e-255 805.0
PYH3_k127_7577052_1 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000243 617.0
PYH3_k127_7577052_2 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001273 597.0
PYH3_k127_7577052_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 389.0
PYH3_k127_7577052_4 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000000000000000003556 197.0
PYH3_k127_7577052_5 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic - - - 0.00000000000000000000000000000000000001466 151.0
PYH3_k127_7577052_6 - - - - 0.00000000000003183 79.0
PYH3_k127_7578805_0 PFAM Glycosyl transferase family 2 - - - 2.88e-278 867.0
PYH3_k127_7578805_1 Acyl-CoA synthetase (AMP-forming) AMP-acid ligase II K00666 - - 5.037e-235 738.0
PYH3_k127_7578805_10 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 473.0
PYH3_k127_7578805_11 DNA protecting protein DprA K04096 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 425.0
PYH3_k127_7578805_12 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003386 419.0
PYH3_k127_7578805_13 Peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009374 413.0
PYH3_k127_7578805_14 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003103 326.0
PYH3_k127_7578805_15 amino acid K03294,K13868 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 339.0
PYH3_k127_7578805_16 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006295 314.0
PYH3_k127_7578805_17 glycolate biosynthetic process K01560,K07025 - 3.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000001551 243.0
PYH3_k127_7578805_18 LexA-binding, inner membrane-associated putative hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000001171 226.0
PYH3_k127_7578805_19 DinB superfamily - - - 0.00000000000000000000000000000000000000000008571 164.0
PYH3_k127_7578805_2 Protein of unknown function (DUF1800) - - - 1.556e-210 677.0
PYH3_k127_7578805_20 BioY family K03523 - - 0.000000000000000000000000000000000000000006391 160.0
PYH3_k127_7578805_21 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000001071 164.0
PYH3_k127_7578805_22 COG0500 SAM-dependent methyltransferases - - - 0.000000000000000000000000000000000681 140.0
PYH3_k127_7578805_23 Helix-turn-helix XRE-family like proteins - - - 0.00000000000000000000000000000588 128.0
PYH3_k127_7578805_24 PFAM Rieske 2Fe-2S K00363 - 1.7.1.15 0.000000000000000000000000000007249 121.0
PYH3_k127_7578805_25 - - - - 0.00000000000000000000000001957 116.0
PYH3_k127_7578805_26 Cupin domain - - - 0.00000000000000000000002504 104.0
PYH3_k127_7578805_3 Protein of unknown function (DUF1501) - - - 1.518e-196 619.0
PYH3_k127_7578805_32 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.0000008887 57.0
PYH3_k127_7578805_33 peroxiredoxin activity K02199 - - 0.000006032 54.0
PYH3_k127_7578805_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 621.0
PYH3_k127_7578805_5 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001297 595.0
PYH3_k127_7578805_6 Putative modulator of DNA gyrase K03568 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 591.0
PYH3_k127_7578805_7 Belongs to the peptidase M24B family K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006311 581.0
PYH3_k127_7578805_8 TIGRFAM phytoene desaturase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007674 566.0
PYH3_k127_7578805_9 Ring hydroxylating alpha subunit (catalytic domain) K00479 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002095 481.0
PYH3_k127_764220_0 SelR domain K07305 - 1.8.4.12 0.000000000000000000000000000000000000000000000000000004367 191.0
PYH3_k127_764220_1 PFAM transposase IS116 IS110 IS902 family protein - - - 0.000000000000000000000000000003315 134.0
PYH3_k127_7674887_0 Belongs to the DNA polymerase type-C family. DnaE2 subfamily K14162 - 2.7.7.7 0.0 1202.0
PYH3_k127_7674887_1 PFAM Cytochrome c assembly protein K02198 - - 1.953e-304 945.0
PYH3_k127_7674887_10 Protein of unknown function (DUF2934) - - - 0.0006895 47.0
PYH3_k127_7674887_2 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005131 397.0
PYH3_k127_7674887_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001871 373.0
PYH3_k127_7674887_4 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002902 254.0
PYH3_k127_7674887_5 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000000003283 171.0
PYH3_k127_7674887_6 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000004278 122.0
PYH3_k127_7674887_7 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000008343 94.0
PYH3_k127_7674887_9 - - - - 0.0000000000000006251 88.0
PYH3_k127_7706709_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 0.0 1302.0
PYH3_k127_7706709_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 5.161e-236 740.0
PYH3_k127_7706709_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001242 275.0
PYH3_k127_7706709_11 CAAX protease self-immunity K07052 - - 0.0000000000000000000000000000000000000000000000003894 189.0
PYH3_k127_7706709_12 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0008144,GO:0008150,GO:0009266,GO:0009314,GO:0009405,GO:0009408,GO:0009628,GO:0009966,GO:0009967,GO:0009986,GO:0009987,GO:0010646,GO:0010647,GO:0016032,GO:0016462,GO:0016465,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0018995,GO:0019058,GO:0019068,GO:0020003,GO:0022610,GO:0023051,GO:0023056,GO:0030430,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033643,GO:0033644,GO:0033646,GO:0033647,GO:0033648,GO:0033655,GO:0035639,GO:0035821,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0043169,GO:0043226,GO:0043227,GO:0043230,GO:0043656,GO:0043657,GO:0043900,GO:0043903,GO:0044174,GO:0044175,GO:0044183,GO:0044215,GO:0044216,GO:0044217,GO:0044218,GO:0044279,GO:0044403,GO:0044406,GO:0044419,GO:0044421,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0044650,GO:0044764,GO:0046812,GO:0046872,GO:0048518,GO:0048522,GO:0048583,GO:0048584,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051704,GO:0051817,GO:0052047,GO:0052212,GO:0061077,GO:0065007,GO:0065010,GO:0097159,GO:0097367,GO:0101031,GO:1901222,GO:1901224,GO:1901265,GO:1901363,GO:1902531,GO:1902533,GO:1990220,GO:2000535 - 0.0000000000000000000000000000000000000000002566 160.0
PYH3_k127_7706709_13 Transposase IS200 like K07491 - - 0.000000000000000000000000002479 113.0
PYH3_k127_7706709_14 - - - - 0.000000000000000009686 92.0
PYH3_k127_7706709_15 - - - - 0.0000000000000005515 83.0
PYH3_k127_7706709_16 - - - - 0.000001946 60.0
PYH3_k127_7706709_17 GHMP kinases N terminal domain K07031 - 2.7.1.168 0.000007146 49.0
PYH3_k127_7706709_2 extracellular solute-binding protein, family 5 K02035 - - 8.027e-198 635.0
PYH3_k127_7706709_3 aminopeptidase activity K01266 - 3.4.11.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006227 523.0
PYH3_k127_7706709_4 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 496.0
PYH3_k127_7706709_5 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000378 479.0
PYH3_k127_7706709_6 Belongs to the GSP D family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 435.0
PYH3_k127_7706709_7 YmdB-like protein K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 373.0
PYH3_k127_7706709_8 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005927 329.0
PYH3_k127_7706709_9 Beta-lactamase K17836 - 3.5.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 307.0
PYH3_k127_7710014_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 1.607e-268 866.0
PYH3_k127_7710014_1 Bacterial protein of unknown function (DUF885) - - - 5.046e-231 730.0
PYH3_k127_7710014_10 Deoxynucleoside kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 322.0
PYH3_k127_7710014_11 FeoA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002241 286.0
PYH3_k127_7710014_12 polysaccharide deacetylase K22278 - 3.5.1.104 0.00000000000000000000000000000000000000000000000000000000000000004226 231.0
PYH3_k127_7710014_13 Belongs to the DNA glycosylase MPG family K03652 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000397 227.0
PYH3_k127_7710014_14 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000002037 222.0
PYH3_k127_7710014_15 Redoxin K03564 - 1.11.1.15 0.00000000000000000000000000000000000000000004174 162.0
PYH3_k127_7710014_16 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.00000000004793 67.0
PYH3_k127_7710014_17 - - - - 0.000002449 57.0
PYH3_k127_7710014_2 Bacterial protein of unknown function (DUF885) - - - 1.063e-206 658.0
PYH3_k127_7710014_3 H( )-stimulated, divalent metal cation uptake system K03322 - - 5.534e-201 634.0
PYH3_k127_7710014_4 Belongs to the GARS family K01945 - 6.3.4.13 6.895e-197 622.0
PYH3_k127_7710014_5 PFAM Aminotransferase class-III K01845 - 5.4.3.8 3.046e-195 617.0
PYH3_k127_7710014_6 aconitate hydratase activity K01681 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0005506,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0008198,GO:0009060,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015980,GO:0016020,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017144,GO:0019541,GO:0019679,GO:0019752,GO:0030312,GO:0030350,GO:0032787,GO:0040007,GO:0042221,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0045333,GO:0046459,GO:0046872,GO:0046914,GO:0047456,GO:0048037,GO:0050896,GO:0051536,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:1901363 4.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 595.0
PYH3_k127_7710014_7 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000369 442.0
PYH3_k127_7710014_8 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008539 435.0
PYH3_k127_7710014_9 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
PYH3_k127_7811530_0 Mur ligase middle domain K02558 - 6.3.2.45 3.189e-201 642.0
PYH3_k127_7811530_1 PFAM peptidase M61 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001216 460.0
PYH3_k127_7811530_2 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001999 353.0
PYH3_k127_7811530_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007073 309.0
PYH3_k127_7811530_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000001332 93.0
PYH3_k127_7827940_0 Cytochrome c - - - 0.0 1095.0
PYH3_k127_7827940_1 Belongs to the peptidase S41A family K03797 - 3.4.21.102 1.772e-253 799.0
PYH3_k127_7827940_10 HAD-superfamily hydrolase, subfamily IIB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 341.0
PYH3_k127_7827940_11 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 319.0
PYH3_k127_7827940_12 Catalyzes the ferrous insertion into protoporphyrin IX K01772 GO:0003674,GO:0003824,GO:0004325,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 308.0
PYH3_k127_7827940_13 Amidinotransferase K01482 - 3.5.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 297.0
PYH3_k127_7827940_14 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005843 286.0
PYH3_k127_7827940_15 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007634 259.0
PYH3_k127_7827940_16 oxidoreductase activity, acting on diphenols and related substances as donors K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000004885 243.0
PYH3_k127_7827940_17 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000003272 241.0
PYH3_k127_7827940_18 PFAM methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000003521 239.0
PYH3_k127_7827940_19 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000000000000000000000004776 235.0
PYH3_k127_7827940_2 Beta-eliminating lyase K01667 - 4.1.99.1 2.095e-240 761.0
PYH3_k127_7827940_20 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000002583 230.0
PYH3_k127_7827940_21 Cytochrome oxidase assembly protein K02259 - - 0.00000000000000000000000000000000000000000003873 173.0
PYH3_k127_7827940_22 deoxyhypusine monooxygenase activity K00627,K02160,K07402 - 2.3.1.12 0.0000000000000000000000000000000000000000001103 165.0
PYH3_k127_7827940_23 Protein of unknown function (DUF420) K08976 - - 0.00000000000000000000000000000000002699 151.0
PYH3_k127_7827940_24 mttA/Hcf106 family K03117 - - 0.00000000000000004445 83.0
PYH3_k127_7827940_3 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000104 548.0
PYH3_k127_7827940_4 TIGRFAM Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 517.0
PYH3_k127_7827940_5 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002761 482.0
PYH3_k127_7827940_6 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002624 448.0
PYH3_k127_7827940_7 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000459 461.0
PYH3_k127_7827940_8 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 446.0
PYH3_k127_7827940_9 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001971 356.0
PYH3_k127_7994699_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 2.306e-238 751.0
PYH3_k127_7994699_1 class II (D K K01893 - 6.1.1.22 1.187e-231 726.0
PYH3_k127_7994699_2 Arginase family K01476 - 3.5.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 505.0
PYH3_k127_7994699_3 Xylose isomerase-like TIM barrel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 364.0
PYH3_k127_7994699_4 - - - - 0.000000000000000000000000000000000000000000000002678 184.0
PYH3_k127_7994699_5 peptidase S1 and S6 chymotrypsin Hap - - - 0.000000000000000000000000000000000008244 138.0
PYH3_k127_7994699_6 Transposase IS200 like K07491 - - 0.00000000000000000000000000003786 122.0
PYH3_k127_7994699_8 - - - - 0.00002396 55.0
PYH3_k127_7994699_9 RDD domain containing protein - GO:0005575,GO:0005576,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.000043 53.0
PYH3_k127_799677_0 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 308.0
PYH3_k127_799677_1 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000002023 182.0
PYH3_k127_799677_2 Regulatory protein - - - 0.0000000000000000000000000000000000000000001588 162.0
PYH3_k127_799677_3 phosphorelay signal transduction system - - - 0.00000001167 64.0
PYH3_k127_806839_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009942 416.0
PYH3_k127_806839_1 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 385.0
PYH3_k127_806839_2 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001912 275.0
PYH3_k127_806839_3 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000008455 182.0
PYH3_k127_8271284_0 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005383 610.0
PYH3_k127_8271284_1 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 395.0
PYH3_k127_8271284_2 PFAM von Willebrand factor type A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003085 391.0
PYH3_k127_8271284_3 von Willebrand factor, type A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 370.0
PYH3_k127_8271284_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001309 317.0
PYH3_k127_8271284_5 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001431 289.0
PYH3_k127_8271284_6 von Willebrand factor (vWF) type A domain - - - 0.00000000000000000000000000000000000000000016 170.0
PYH3_k127_8271284_7 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000000000000004642 119.0
PYH3_k127_8271284_8 - - - - 0.00000000008397 64.0
PYH3_k127_8271284_9 - - - - 0.00003191 53.0
PYH3_k127_8389198_0 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 596.0
PYH3_k127_8389198_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009288 554.0
PYH3_k127_8389198_10 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000002778 88.0
PYH3_k127_8389198_11 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000001168 80.0
PYH3_k127_8389198_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 329.0
PYH3_k127_8389198_3 cyclic nucleotide-binding K10914 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 317.0
PYH3_k127_8389198_4 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000005648 259.0
PYH3_k127_8389198_5 R3H domain K06346 - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
PYH3_k127_8389198_6 Carbonic anhydrase K01673 - 4.2.1.1 0.0000000000000000000000000000000000000000000000000413 194.0
PYH3_k127_8389198_7 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000001554 143.0
PYH3_k127_8389198_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000008788 112.0
PYH3_k127_8402709_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 1.315e-240 754.0
PYH3_k127_8402709_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 3.276e-205 647.0
PYH3_k127_8402709_2 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008167 285.0
PYH3_k127_8402709_3 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0000000000000000000000000000001966 129.0
PYH3_k127_8402709_4 Putative zinc-finger - - - 0.00000000000000000003022 92.0
PYH3_k127_8402709_5 Acetyltransferase (GNAT) family - - - 0.0000000000000001297 81.0
PYH3_k127_8435535_0 PFAM Mur ligase K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 513.0
PYH3_k127_8435535_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002219 435.0
PYH3_k127_8435535_10 - - - - 0.00000000000000000000000000000000000000000000000001049 191.0
PYH3_k127_8435535_11 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.000000000000000000000000000000000000000000000002899 176.0
PYH3_k127_8435535_12 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000003603 160.0
PYH3_k127_8435535_13 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000107 161.0
PYH3_k127_8435535_14 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.0000000000000000000000000000000000000000239 168.0
PYH3_k127_8435535_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002026 426.0
PYH3_k127_8435535_3 PFAM Response regulator receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000251 392.0
PYH3_k127_8435535_4 PFAM Short-chain dehydrogenase reductase SDR K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001826 330.0
PYH3_k127_8435535_5 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003628 307.0
PYH3_k127_8435535_6 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 303.0
PYH3_k127_8435535_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 290.0
PYH3_k127_8435535_8 Peptidase C26 K07010 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000572 251.0
PYH3_k127_8435535_9 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002359 241.0
PYH3_k127_8560184_0 4 iron, 4 sulfur cluster binding - - - 1.028e-277 864.0
PYH3_k127_8560184_1 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 8.76e-213 670.0
PYH3_k127_8560184_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005769 503.0
PYH3_k127_8560184_3 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 474.0
PYH3_k127_8560184_4 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 350.0
PYH3_k127_8560184_5 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003379 295.0
PYH3_k127_8560184_6 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000001066 207.0
PYH3_k127_8560184_7 lactoylglutathione lyase activity - - - 0.000000000000000000000000000000000000000005851 159.0
PYH3_k127_8560184_8 Frataxin-like domain K06202 - - 0.00000000000000000000000000000000000009498 144.0
PYH3_k127_8560184_9 - - - - 0.0000000000000000000000003077 116.0
PYH3_k127_8660555_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 5.258e-302 937.0
PYH3_k127_8660555_1 Cysteine-rich domain K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003918 260.0
PYH3_k127_8660555_2 Belongs to the Dps family K04047 - - 0.000000000000000000000000000000000000000000000000000002756 196.0
PYH3_k127_8660555_3 Protein of unknown function, DUF255 K06888 - - 0.000000000000000000000000000000000000000000000000006378 186.0
PYH3_k127_8660555_4 ACT domain - - - 0.0000000001234 66.0
PYH3_k127_8680577_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 4.928e-309 962.0
PYH3_k127_8680577_1 Phosphoglycerate mutase family K08296 - - 0.00000000000000000000000000000000000000000000000000000003205 201.0
PYH3_k127_8734752_0 PFAM Peptidase M1, membrane alanine aminopeptidase K01256 - 3.4.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 372.0
PYH3_k127_8734752_1 Amidohydrolase family - - - 0.0001812 44.0
PYH3_k127_8796523_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K04108 - 1.3.7.9 7.456e-227 732.0
PYH3_k127_8796523_1 Peptidase S46 - - - 3.805e-226 724.0
PYH3_k127_8796523_10 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000002744 254.0
PYH3_k127_8796523_11 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000001254 182.0
PYH3_k127_8796523_12 Enoyl-CoA hydratase K07537 - 4.2.1.100 0.0000000000000000000000000000000000000000000003654 177.0
PYH3_k127_8796523_13 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000002369 145.0
PYH3_k127_8796523_14 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000002179 143.0
PYH3_k127_8796523_15 - - - - 0.0000000000000000000000009509 109.0
PYH3_k127_8796523_16 YtxH-like protein - - - 0.000000000000000000000003352 106.0
PYH3_k127_8796523_17 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000006319 106.0
PYH3_k127_8796523_18 Domain of unknown function (DUF1330) - - - 0.00000000000002552 81.0
PYH3_k127_8796523_2 Belongs to the citrate synthase family K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002 588.0
PYH3_k127_8796523_3 PFAM aminotransferase class V K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004244 559.0
PYH3_k127_8796523_4 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 553.0
PYH3_k127_8796523_5 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 329.0
PYH3_k127_8796523_6 oxidoreductase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 323.0
PYH3_k127_8796523_7 KR domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003876 302.0
PYH3_k127_8796523_8 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 291.0
PYH3_k127_8796523_9 amidohydrolase K07045 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001125 278.0
PYH3_k127_8828788_0 Elongation factor SelB, winged helix K03833 - - 1.876e-232 737.0
PYH3_k127_8828788_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 1.065e-196 619.0
PYH3_k127_8828788_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 554.0
PYH3_k127_8828788_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009099 390.0
PYH3_k127_8828788_4 PFAM Alcohol dehydrogenase zinc-binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 366.0
PYH3_k127_8828788_5 Tetratricopeptide TPR_2 repeat protein K12600 - - 0.00001109 55.0
PYH3_k127_8922918_0 HD domain - - - 9.814e-248 781.0
PYH3_k127_8922918_1 IMS family HHH motif K02346 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000403 559.0
PYH3_k127_8922918_10 Protein of unknown function (DUF3592) - - - 0.0000001184 60.0
PYH3_k127_8922918_11 protein possibly involved in aromatic compounds catabolism K02614 - - 0.000002546 58.0
PYH3_k127_8922918_12 Acetyltransferase (GNAT) domain - - - 0.00002003 53.0
PYH3_k127_8922918_2 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003025 462.0
PYH3_k127_8922918_3 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 457.0
PYH3_k127_8922918_4 HNH endonuclease K07454 - - 0.00000000000000000000000000000000000000000000000000000002154 207.0
PYH3_k127_8922918_5 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000001692 189.0
PYH3_k127_8922918_6 - - - - 0.00000000000000000000000000000000000000000000000003691 192.0
PYH3_k127_8922918_7 Winged helix DNA-binding domain - - - 0.000000000000000000000000000000000001148 141.0
PYH3_k127_8922918_8 HNH endonuclease - - - 0.00000000000000000001689 95.0
PYH3_k127_8922918_9 PEGA domain - - - 0.0000000462 64.0
PYH3_k127_8980885_0 Peptidase S9 prolyl oligopeptidase active site - - - 1.477e-197 636.0
PYH3_k127_8980885_1 Nucleic acid binding K03698 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 479.0
PYH3_k127_8980885_2 Protein involved in outer membrane biogenesis K07289 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000653 463.0
PYH3_k127_8980885_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003569 430.0
PYH3_k127_8980885_4 Peptidylprolyl isomerase K03771 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009139 356.0
PYH3_k127_8980885_5 region 4 type 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008364 275.0
PYH3_k127_8980885_6 Sigma factor PP2C-like phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000002464 232.0
PYH3_k127_8980885_7 Peptidase family M1 domain - - - 0.0000000000000000000000000000002393 129.0
PYH3_k127_8980885_8 - - - - 0.000000000000000000000001949 108.0
PYH3_k127_8980885_9 Periplasmic or secreted lipoprotein - - - 0.000000000000000001417 96.0
PYH3_k127_9139968_0 Phosphate acyltransferases K00655,K01897 - 2.3.1.51,6.2.1.3 0.0 1026.0
PYH3_k127_9139968_1 Superoxide dismutase K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000008982 181.0
PYH3_k127_9139968_2 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.00000000000000000000000000000000002 135.0
PYH3_k127_9156641_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 560.0
PYH3_k127_9156641_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.000000000000000000000000000000000000000000000000000000000000002135 220.0
PYH3_k127_9156641_2 HicB_like antitoxin of bacterial toxin-antitoxin system - - - 0.0000000000000002993 83.0
PYH3_k127_9156641_3 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000001807 68.0
PYH3_k127_919588_0 diguanylate cyclase K02030,K06950,K16923 - - 0.0 1023.0
PYH3_k127_919588_1 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 1.815e-257 804.0
PYH3_k127_919588_11 endonuclease activity - - - 0.0000000000000000000002835 100.0
PYH3_k127_919588_12 - - - - 0.00000000000000000002069 100.0
PYH3_k127_919588_13 Large family of predicted nucleotide-binding domains - - - 0.0000000000000000001734 89.0
PYH3_k127_919588_2 Zinc carboxypeptidase - - - 4.552e-231 730.0
PYH3_k127_919588_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007056 584.0
PYH3_k127_919588_4 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 295.0
PYH3_k127_919588_5 Cytochrome C biogenesis protein K06196,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005291 287.0
PYH3_k127_919588_6 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000001754 236.0
PYH3_k127_919588_7 Glutathione peroxidase K02199 - - 0.0000000000000000000000000000000000000000000001162 185.0
PYH3_k127_919588_8 Disulphide bond corrector protein DsbC - - - 0.0000000000000000000000000000000000000179 154.0
PYH3_k127_919588_9 - - - - 0.0000000000000000000000000000000000007646 142.0
PYH3_k127_9213503_0 Amino acid permease - - - 2.979e-301 945.0
PYH3_k127_9213503_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006356 547.0
PYH3_k127_9213503_10 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000002197 68.0
PYH3_k127_9213503_2 PFAM Ppx GppA phosphatase K01524 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005539 488.0
PYH3_k127_9213503_3 lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001358 390.0
PYH3_k127_9213503_4 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 347.0
PYH3_k127_9213503_5 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007019 340.0
PYH3_k127_9213503_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001105 262.0
PYH3_k127_9213503_7 Las17-binding protein actin regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002869 261.0
PYH3_k127_9213503_8 PFAM Cytochrome c, class I - - - 0.00000000000000000000000000000000000000000000000005013 184.0
PYH3_k127_9252158_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 1.332e-249 777.0
PYH3_k127_9252158_1 His Kinase A (phosphoacceptor) domain - - - 1.357e-234 763.0
PYH3_k127_9252158_2 3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase) K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002551 419.0
PYH3_k127_9252158_3 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008635 404.0
PYH3_k127_9252158_4 - - - - 0.000000000000000000000000000000000000000000007496 172.0
PYH3_k127_9252158_5 Endonuclease containing a URI domain K07461 - - 0.000000000000000000000000002366 114.0
PYH3_k127_9252158_6 - - - - 0.0000000000006615 76.0
PYH3_k127_9295291_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.429e-227 709.0
PYH3_k127_9295291_1 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001771 531.0
PYH3_k127_9295291_10 general secretion pathway protein - - - 0.00000003385 57.0
PYH3_k127_9295291_2 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 456.0
PYH3_k127_9295291_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 335.0
PYH3_k127_9295291_4 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009936 298.0
PYH3_k127_9295291_5 Belongs to the HesB IscA family - - - 0.0000000000000000000000000000000000000000000000000000001359 199.0
PYH3_k127_9295291_6 Protein of unknown function (DUF3467) - - - 0.000000000000000000000000000000000001927 139.0
PYH3_k127_9295291_7 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000001156 109.0
PYH3_k127_9295291_8 - - - - 0.0000000000000000007872 89.0
PYH3_k127_9295291_9 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0000000000000009001 77.0
PYH3_k127_9311998_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 1.539e-212 667.0
PYH3_k127_9311998_1 von Willebrand factor, type A K07114 - - 3.922e-204 662.0
PYH3_k127_9311998_2 Domain of unknown function (DUF4139) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 612.0
PYH3_k127_9311998_3 Protein kinase domain K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003001 377.0
PYH3_k127_9311998_4 protein kinase activity - - - 0.0000000000000000000000000000000000000000008277 170.0
PYH3_k127_9557403_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00282 - 1.4.4.2 6.771e-208 659.0
PYH3_k127_9557403_1 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 554.0
PYH3_k127_9557403_2 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008184 326.0
PYH3_k127_9557403_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000002114 170.0
PYH3_k127_962428_0 Required for chromosome condensation and partitioning K03529 - - 0.0 1020.0
PYH3_k127_962428_1 DNA polymerase X family K02347 - - 5.815e-262 818.0
PYH3_k127_962428_2 PFAM peptidase - - - 6.063e-218 691.0
PYH3_k127_962428_3 PFAM FAD dependent oxidoreductase K03153 - 1.4.3.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 307.0
PYH3_k127_962428_4 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000004304 266.0
PYH3_k127_962428_5 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002434 247.0
PYH3_k127_962428_6 Histidine kinase K02478 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000008816 249.0
PYH3_k127_962428_7 Domain of unknown function (DUF2520) - - - 0.00000000000000000000000000000000000000000000000000000000003158 216.0
PYH3_k127_962428_8 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000002237 205.0
PYH3_k127_962428_9 - - - - 0.00000000000000000000000000000000329 135.0
PYH3_k127_9642596_0 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 576.0
PYH3_k127_9642596_1 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000002507 263.0
PYH3_k127_9642596_2 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000000008408 253.0
PYH3_k127_9642596_3 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000003207 150.0
PYH3_k127_9642596_4 TPR repeat - - - 0.000000000000000000000000002106 124.0
PYH3_k127_9642596_5 - - - - 0.00000000000000000000000005252 109.0
PYH3_k127_9642596_6 transport - - - 0.00000000000000000001949 98.0
PYH3_k127_999961_0 lipopolysaccharide transport K22110 - - 0.0 1446.0
PYH3_k127_999961_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 - 4.1.1.32 2.856e-278 867.0
PYH3_k127_999961_10 PFAM peptidase S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003505 439.0
PYH3_k127_999961_11 L-lysine 6-monooxygenase (NADPH-requiring) K00384 - 1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 351.0
PYH3_k127_999961_12 Cupin 2, conserved barrel domain protein K11477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002239 324.0
PYH3_k127_999961_13 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 322.0
PYH3_k127_999961_14 Belongs to the MIP aquaporin (TC 1.A.8) family K06188 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002499 315.0
PYH3_k127_999961_15 Gram-negative bacterial TonB protein C-terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007072 314.0
PYH3_k127_999961_16 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006163 296.0
PYH3_k127_999961_17 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002966 284.0
PYH3_k127_999961_18 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009775 299.0
PYH3_k127_999961_19 NADPH-dependent FMN reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005322 276.0
PYH3_k127_999961_2 choline dehydrogenase activity - - - 1.443e-276 857.0
PYH3_k127_999961_20 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004907 276.0
PYH3_k127_999961_21 lipid kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000002073 242.0
PYH3_k127_999961_22 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000001887 197.0
PYH3_k127_999961_23 - - - - 0.000000000000000000000000000000000000000000000000002521 192.0
PYH3_k127_999961_24 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K05788 - - 0.00000000000000000000000000000000000000000002351 162.0
PYH3_k127_999961_25 - - - - 0.000000000000000000000000000000000000003306 151.0
PYH3_k127_999961_26 Transposase IS200 like K07491 - - 0.0000000000000000000000000000000003354 137.0
PYH3_k127_999961_27 PFAM Methylated-DNA- protein -cysteine S-methyltransferase DNA binding K07443 - - 0.000000000000000000000000000000001709 133.0
PYH3_k127_999961_28 - - - - 0.00000000000000000000000000005019 118.0
PYH3_k127_999961_29 Acylphosphatase K01512 - 3.6.1.7 0.0000000000000000000000008777 106.0
PYH3_k127_999961_3 Sigma factor PP2C-like phosphatases - - - 2.746e-222 704.0
PYH3_k127_999961_30 ferredoxin-NADP+ reductase activity - - - 0.000000000000000000000008473 103.0
PYH3_k127_999961_31 - - - - 0.0000000000000000002801 98.0
PYH3_k127_999961_32 Putative zinc-finger - - - 0.000000000003887 77.0
PYH3_k127_999961_33 Putative zinc-finger - - - 0.0000000004214 66.0
PYH3_k127_999961_34 - - - - 0.0000005374 55.0
PYH3_k127_999961_4 gluconolactonase activity K01053 - 3.1.1.17 1.815e-203 646.0
PYH3_k127_999961_5 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006752 581.0
PYH3_k127_999961_6 alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004567 548.0
PYH3_k127_999961_7 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003807 524.0
PYH3_k127_999961_8 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009282 508.0
PYH3_k127_999961_9 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 450.0