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Overview

ID MAG03222
Name PYH3_bin.27
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family Burkholderiaceae
Genus JAKOQB01
Species
Assembly information
Completeness (%) 98.14
Contamination (%) 2.96
GC content (%) 64.0
N50 (bp) 19,166
Genome size (bp) 4,392,192

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes4366

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_101820_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 0.0 1091.0
PYH3_k127_101820_1 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.0 1014.0
PYH3_k127_101820_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 1.776e-256 792.0
PYH3_k127_101820_11 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 1.691e-248 780.0
PYH3_k127_101820_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 1.607e-247 767.0
PYH3_k127_101820_13 Catalyzes the transfer of electrons from NADH to quinone K00342 - 1.6.5.3 8.014e-246 778.0
PYH3_k127_101820_14 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 GO:0000015,GO:0000287,GO:0003674,GO:0003824,GO:0004634,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005856,GO:0005975,GO:0006082,GO:0006090,GO:0006091,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009986,GO:0009987,GO:0016052,GO:0016053,GO:0016310,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019637,GO:0019693,GO:0019752,GO:0032787,GO:0032991,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042802,GO:0042866,GO:0043167,GO:0043169,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046031,GO:0046034,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046872,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1902494 4.2.1.11 4.482e-241 749.0
PYH3_k127_101820_15 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 3.168e-227 721.0
PYH3_k127_101820_16 Belongs to the ABC transporter superfamily K02031,K02032,K10823,K13896,K15583 - - 1.261e-223 706.0
PYH3_k127_101820_17 GMC oxidoreductase - - - 2.639e-222 701.0
PYH3_k127_101820_18 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 7.557e-214 681.0
PYH3_k127_101820_19 Cys/Met metabolism PLP-dependent enzyme K01761 - 4.4.1.11 1.898e-207 657.0
PYH3_k127_101820_2 TIGRFAM TRAP transporter, 4TM 12TM fusion protein - - - 1.5e-323 1004.0
PYH3_k127_101820_20 Homoserine dehydrogenase, NAD binding domain-containing protein - - - 1.868e-203 647.0
PYH3_k127_101820_21 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 3.311e-195 611.0
PYH3_k127_101820_22 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 587.0
PYH3_k127_101820_23 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 561.0
PYH3_k127_101820_24 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 545.0
PYH3_k127_101820_25 Binding-protein-dependent transport system inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002493 499.0
PYH3_k127_101820_26 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 488.0
PYH3_k127_101820_27 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 484.0
PYH3_k127_101820_28 TRAP transporter solute receptor TAXI family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 473.0
PYH3_k127_101820_29 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 471.0
PYH3_k127_101820_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.82e-318 981.0
PYH3_k127_101820_30 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004386 457.0
PYH3_k127_101820_31 TIGRFAM LAO AO transport system ATPase K07588 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 428.0
PYH3_k127_101820_32 3-oxoacid CoA-transferase, A subunit K01028 - 2.8.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008808 394.0
PYH3_k127_101820_33 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000602 387.0
PYH3_k127_101820_34 short-chain dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004609 355.0
PYH3_k127_101820_35 CoA-transferase activity K01027,K01029 - 2.8.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 348.0
PYH3_k127_101820_36 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004109 352.0
PYH3_k127_101820_37 TIGRFAM cation diffusion facilitator family transporter K16264 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 340.0
PYH3_k127_101820_38 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006754 325.0
PYH3_k127_101820_4 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 1.839e-315 971.0
PYH3_k127_101820_40 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 334.0
PYH3_k127_101820_41 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006119 318.0
PYH3_k127_101820_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 308.0
PYH3_k127_101820_43 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 308.0
PYH3_k127_101820_44 Acetolactate synthase, small subunit K01653 GO:0003674,GO:0003824,GO:0003984,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005948,GO:0006082,GO:0006520,GO:0006549,GO:0006573,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009099,GO:0009987,GO:0016053,GO:0016740,GO:0016744,GO:0019752,GO:0032991,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607,GO:1902494,GO:1990234 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 282.0
PYH3_k127_101820_45 RNA polymerase K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007383 281.0
PYH3_k127_101820_46 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000009433 275.0
PYH3_k127_101820_47 Uncharacterised 5xTM membrane BCR, YitT family COG1284 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006695 265.0
PYH3_k127_101820_48 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000008717 251.0
PYH3_k127_101820_49 NUDIX domain K01515 - 3.6.1.13 0.00000000000000000000000000000000000000000000000000000000000000000001937 238.0
PYH3_k127_101820_5 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter, MnhA subunit K00341 - 1.6.5.3 6.4e-313 970.0
PYH3_k127_101820_50 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000003393 236.0
PYH3_k127_101820_51 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000003892 219.0
PYH3_k127_101820_52 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000001531 199.0
PYH3_k127_101820_53 Protein of unknown function (DUF1624) - - - 0.00000000000000000000000000000000000000000000000000000003134 206.0
PYH3_k127_101820_54 - - - - 0.0000000000000000000000000000000000000000000000000000002628 204.0
PYH3_k127_101820_55 PGAP1-like protein - - - 0.000000000000000000000000000000000000000000001211 178.0
PYH3_k127_101820_56 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000001094 160.0
PYH3_k127_101820_57 Domain of unknown function (DUF1330) - - - 0.0000000000000000000000000000000000000001642 152.0
PYH3_k127_101820_58 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000000000003237 151.0
PYH3_k127_101820_59 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000000005539 146.0
PYH3_k127_101820_6 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 GO:0001775,GO:0002376,GO:0003674,GO:0003824,GO:0003883,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006213,GO:0006220,GO:0006221,GO:0006241,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008283,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009163,GO:0009165,GO:0009199,GO:0009201,GO:0009208,GO:0009209,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0015949,GO:0016874,GO:0016879,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032943,GO:0034404,GO:0034641,GO:0034654,GO:0042098,GO:0042100,GO:0042110,GO:0042113,GO:0042221,GO:0042455,GO:0042493,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045321,GO:0046036,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0046649,GO:0046651,GO:0050896,GO:0055086,GO:0070661,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.4.2 9.132e-300 928.0
PYH3_k127_101820_60 YdjC-like protein K03478 - 3.5.1.105 0.0000000000000000000000000000000000156 143.0
PYH3_k127_101820_61 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.0000000000000000000000000000000001437 135.0
PYH3_k127_101820_62 Twin-arginine translocation pathway signal protein - - - 0.0000000000000000000000000000000004461 138.0
PYH3_k127_101820_63 23S rRNA-intervening sequence protein - - - 0.00000000000000000000000000000008123 128.0
PYH3_k127_101820_64 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000002116 131.0
PYH3_k127_101820_65 Protein of unknown function (DUF3024) - - - 0.00000000000000000000000000001947 121.0
PYH3_k127_101820_66 GIY-YIG catalytic domain K07461 - - 0.0000000000000000000000000001004 118.0
PYH3_k127_101820_67 PFAM RDD domain containing protein - - - 0.0000000000000000000000000002122 121.0
PYH3_k127_101820_68 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000004275 108.0
PYH3_k127_101820_69 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000001903 107.0
PYH3_k127_101820_7 Electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 2.624e-279 868.0
PYH3_k127_101820_70 Protein of unknown function (DUF3106) - - - 0.000000000000000004375 91.0
PYH3_k127_101820_71 Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress K04083 - - 0.00000000000101 74.0
PYH3_k127_101820_72 Protein of unknown function (DUF3619) - - - 0.0000000001122 70.0
PYH3_k127_101820_73 - - - - 0.000000000181 70.0
PYH3_k127_101820_8 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 8.253e-266 826.0
PYH3_k127_101820_9 Belongs to the TPP enzyme family K01652 - 2.2.1.6 3.376e-265 829.0
PYH3_k127_106346_0 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 358.0
PYH3_k127_106346_1 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 342.0
PYH3_k127_106346_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007807 263.0
PYH3_k127_106346_3 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000002101 191.0
PYH3_k127_1109027_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 634.0
PYH3_k127_1109027_1 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000002074 168.0
PYH3_k127_1229461_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 6.01e-220 691.0
PYH3_k127_1229461_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 1.896e-209 660.0
PYH3_k127_1229461_10 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009326 416.0
PYH3_k127_1229461_11 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008779 411.0
PYH3_k127_1229461_12 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 401.0
PYH3_k127_1229461_13 Glutathione S-transferase K03599 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 367.0
PYH3_k127_1229461_14 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 368.0
PYH3_k127_1229461_15 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 364.0
PYH3_k127_1229461_16 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003632 337.0
PYH3_k127_1229461_17 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 328.0
PYH3_k127_1229461_18 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000683 316.0
PYH3_k127_1229461_19 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 289.0
PYH3_k127_1229461_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 580.0
PYH3_k127_1229461_20 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000632 278.0
PYH3_k127_1229461_21 VacJ family lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002052 275.0
PYH3_k127_1229461_22 Cytochrome C1 K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008835 276.0
PYH3_k127_1229461_23 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
PYH3_k127_1229461_24 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000001897 266.0
PYH3_k127_1229461_25 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000003476 232.0
PYH3_k127_1229461_26 toluene tolerance K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000002497 230.0
PYH3_k127_1229461_27 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000006253 213.0
PYH3_k127_1229461_28 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000002298 209.0
PYH3_k127_1229461_29 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000000000000000003291 192.0
PYH3_k127_1229461_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 563.0
PYH3_k127_1229461_30 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.00000000000000000000000000000000000000000000000006532 188.0
PYH3_k127_1229461_31 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.00000000000000000000000000000000000000000000000006812 179.0
PYH3_k127_1229461_32 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 - - 0.000000000000000000000000000000000000000000000001708 181.0
PYH3_k127_1229461_33 Stringent starvation protein B K03600 - - 0.0000000000000000000000000000000000000000000003376 172.0
PYH3_k127_1229461_34 Phosphoribosyl-ATP K01523 - 3.6.1.31 0.00000000000000000000000000000000000002369 147.0
PYH3_k127_1229461_35 PFAM Transglycosylase-associated protein - - - 0.00000000000000000000000000000000000008726 144.0
PYH3_k127_1229461_36 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.0000000000000000000000000000000000009591 144.0
PYH3_k127_1229461_37 protein domain associated with - - - 0.0000000000000000000000000000000001305 144.0
PYH3_k127_1229461_38 Belongs to the BolA IbaG family - - - 0.000000000000000000000000000002352 123.0
PYH3_k127_1229461_39 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000000002607 109.0
PYH3_k127_1229461_4 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005649 531.0
PYH3_k127_1229461_40 NTP binding protein (Contains STAS domain) K04749,K07122 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0006974,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0033554,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051716 - 0.000000000000004601 78.0
PYH3_k127_1229461_41 FR47-like protein K06976 - - 0.0000000000008401 73.0
PYH3_k127_1229461_42 Cytochrome c K17760 - 1.1.9.1 0.000000000002993 67.0
PYH3_k127_1229461_43 COG2010 Cytochrome c, mono- and diheme variants - - - 0.0003852 45.0
PYH3_k127_1229461_5 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008924 525.0
PYH3_k127_1229461_6 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 451.0
PYH3_k127_1229461_7 Belongs to the peptidase S1C family K04691,K04772 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 441.0
PYH3_k127_1229461_8 ABC transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 434.0
PYH3_k127_1229461_9 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001175 431.0
PYH3_k127_1231110_0 Protein of unknown function (DUF1015) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005347 520.0
PYH3_k127_1231110_1 PFAM aldo keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 494.0
PYH3_k127_1231110_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00520 - 1.16.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000075 489.0
PYH3_k127_1231110_3 PFAM Patatin K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 477.0
PYH3_k127_1231110_4 Lipoprotein - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0009279,GO:0010033,GO:0010243,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031240,GO:0031975,GO:0042221,GO:0044424,GO:0044425,GO:0044444,GO:0044462,GO:0044464,GO:0050896,GO:0071944,GO:0098552,GO:1901652,GO:1901698,GO:1901700 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 457.0
PYH3_k127_1231110_5 Short-chain dehydrogenase reductase SDR K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 357.0
PYH3_k127_1231110_6 Inorganic pyrophosphatase K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000107 268.0
PYH3_k127_1231110_7 Domain of unknown function (DUF427) - - - 0.00000000000000000000000000000000000000001447 156.0
PYH3_k127_1231110_8 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000002474 157.0
PYH3_k127_1231110_9 Protein of unknown function (DUF1622) - - - 0.0000000000000000000000000001376 118.0
PYH3_k127_1237976_0 Ferrous iron transport protein B K04759 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002633 249.0
PYH3_k127_1237976_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type beta chain is a regulatory subunit K02118 - - 0.000000000000000000000000000000000000000000000000000000000000005729 219.0
PYH3_k127_1237976_2 ATP synthase subunit D K02120 - - 0.0000000000000000000000000000000000008618 146.0
PYH3_k127_1262375_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009391 327.0
PYH3_k127_1262375_1 Alpha-tubulin suppressor and related RCC1 domain-containing proteins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003821 263.0
PYH3_k127_1262375_2 pyrroloquinoline quinone binding K12287 - - 0.0000000000003755 83.0
PYH3_k127_1263539_0 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001915 533.0
PYH3_k127_1263539_1 Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002502 430.0
PYH3_k127_1263539_2 Crp-like helix-turn-helix domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008417 343.0
PYH3_k127_1263539_3 Crp Fnr family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009965 314.0
PYH3_k127_1263539_5 SMART Transport-associated and nodulation region K04065 - - 0.00000000000000009952 87.0
PYH3_k127_128381_0 Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate K01712 - 4.2.1.49 1.135e-302 934.0
PYH3_k127_128381_1 Histidine ammonia-lyase K01745 - 4.3.1.3 7.921e-196 628.0
PYH3_k127_128381_2 N-formylglutamate amidohydrolase K01458,K01479 - 3.5.1.68,3.5.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 342.0
PYH3_k127_128381_3 LysR substrate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 329.0
PYH3_k127_128381_4 Amidohydrolase family K01468 - 3.5.2.7 0.000000000000000000000000000000000000000000000000000000248 197.0
PYH3_k127_128381_5 Auxin binding protein - - - 0.00000000000000000000000000000000000000000008211 164.0
PYH3_k127_128381_6 ornithine cyclodeaminase mu-crystallin K01750,K19244 - 1.4.1.1,4.3.1.12 0.00000000000000000000000000001021 123.0
PYH3_k127_1308010_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 9.815e-312 964.0
PYH3_k127_1308010_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K16846 - 4.4.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002297 544.0
PYH3_k127_1308010_2 UTRA domain K03710 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 344.0
PYH3_k127_1308010_3 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004499 326.0
PYH3_k127_1308010_4 Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001679 259.0
PYH3_k127_1308010_5 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000000001999 188.0
PYH3_k127_1308010_6 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000000000000003313 175.0
PYH3_k127_1308010_7 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.00000000000002049 83.0
PYH3_k127_1308010_8 - - - - 0.0001088 51.0
PYH3_k127_1312185_0 Transposase DDE domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009647 432.0
PYH3_k127_1312185_1 PFAM peptidase C14, caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002259 258.0
PYH3_k127_1312185_2 Tetratricopeptide repeat - - - 0.000134 47.0
PYH3_k127_1328247_0 transport system periplasmic component K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 438.0
PYH3_k127_1328247_1 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.0000000000000000000000000000001048 127.0
PYH3_k127_1328247_2 Domain of unknown function (DUF1850) - - - 0.000000000000000003878 89.0
PYH3_k127_1359913_0 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 529.0
PYH3_k127_1359913_1 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008389 480.0
PYH3_k127_1359913_2 Phage integrase, N-terminal SAM-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008848 479.0
PYH3_k127_1359913_3 Phage integrase family - - - 0.00000000000000000000000000000000000000000000000000000000004136 209.0
PYH3_k127_1359913_4 Belongs to the 'phage' integrase family - - - 0.00000000000000000000175 94.0
PYH3_k127_1363814_0 PFAM NADH flavin oxidoreductase NADH oxidase K00219,K09461 - 1.14.13.40,1.3.1.34 0.0 1277.0
PYH3_k127_1363814_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 6.095e-220 692.0
PYH3_k127_1363814_10 PFAM peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000199 387.0
PYH3_k127_1363814_11 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 413.0
PYH3_k127_1363814_12 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 402.0
PYH3_k127_1363814_13 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003613 297.0
PYH3_k127_1363814_14 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009871 258.0
PYH3_k127_1363814_15 ornithine cyclodeaminase K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000001255 250.0
PYH3_k127_1363814_16 Bacterial regulatory helix-turn-helix protein, lysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000002158 236.0
PYH3_k127_1363814_17 - - - - 0.000000000000000000000000000000000000000000000000000000000000003037 224.0
PYH3_k127_1363814_18 carbohydrate transport K11688 - - 0.000000000000000000000000000000000000000000000000000000000000009581 228.0
PYH3_k127_1363814_19 Belongs to the SOS response-associated peptidase family - - - 0.0000000000000000000000000000000000000000000000000007504 191.0
PYH3_k127_1363814_2 Belongs to the thiolase family - - - 1.398e-211 663.0
PYH3_k127_1363814_20 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000003273 152.0
PYH3_k127_1363814_21 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000000000000000001709 113.0
PYH3_k127_1363814_22 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000003954 100.0
PYH3_k127_1363814_23 cobalamin (vitamin B12) biosynthesis CbiX protein K03795 - 4.99.1.3 0.000000000000000000361 95.0
PYH3_k127_1363814_25 L-carnitine dehydratase bile acid-inducible protein F - - - 0.000004319 50.0
PYH3_k127_1363814_26 family) member 1 - - - 0.0003889 48.0
PYH3_k127_1363814_3 Hydantoinase/oxoprolinase K01473 - 3.5.2.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000162 624.0
PYH3_k127_1363814_4 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002854 595.0
PYH3_k127_1363814_5 N-terminal domain of oxidoreductase K07119 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000068 545.0
PYH3_k127_1363814_6 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009784 475.0
PYH3_k127_1363814_7 N-methylhydantoinase B acetone carboxylase alpha subunit K01474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006518,GO:0006575,GO:0006749,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0017168,GO:0034641,GO:0043603,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0051186,GO:0071704,GO:1901564 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 462.0
PYH3_k127_1363814_8 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004872 429.0
PYH3_k127_1363814_9 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 433.0
PYH3_k127_1382132_0 ABC transporter transmembrane region K06147 - - 6.054e-274 862.0
PYH3_k127_1382132_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 445.0
PYH3_k127_1382132_2 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 380.0
PYH3_k127_1382132_3 FtsX-like permease family K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000006352 298.0
PYH3_k127_1382132_4 MAPEG family - - - 0.00000000000000000000000000000000006305 147.0
PYH3_k127_1384776_0 FAD dependent oxidoreductase K07256 - - 1.333e-254 790.0
PYH3_k127_1384776_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.000000000000000000000000000000000000000000000000000004438 193.0
PYH3_k127_1400664_0 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005343 372.0
PYH3_k127_1400664_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003823 335.0
PYH3_k127_1400664_10 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K01563,K11991 - 3.5.4.33,3.8.1.5 0.000000000000000000000000000000000000000000000000000000000000248 232.0
PYH3_k127_1400664_11 Thioesterase-like superfamily K07107 - - 0.0000000000000000000000000000000000000000000001669 171.0
PYH3_k127_1400664_12 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000002477 171.0
PYH3_k127_1400664_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004623 169.0
PYH3_k127_1400664_14 - - - - 0.00000000000000000000000000000000258 131.0
PYH3_k127_1400664_15 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000004115 67.0
PYH3_k127_1400664_16 Domain of unknown function (DUF4936) - - - 0.0000002636 56.0
PYH3_k127_1400664_17 - - - - 0.0004828 44.0
PYH3_k127_1400664_2 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002184 319.0
PYH3_k127_1400664_3 Belongs to the peptidase M16 family K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002705 269.0
PYH3_k127_1400664_4 LD-carboxypeptidase K01297 - 3.4.17.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000103 271.0
PYH3_k127_1400664_5 dna polymerase iii K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000009239 258.0
PYH3_k127_1400664_6 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006825 247.0
PYH3_k127_1400664_7 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000007448 248.0
PYH3_k127_1400664_8 Aminomethyltransferase folate-binding domain K06980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000203 250.0
PYH3_k127_1400664_9 Transport and Golgi organisation 2 - - - 0.000000000000000000000000000000000000000000000000000000000000001997 227.0
PYH3_k127_1405054_0 X-Pro dipeptidyl-peptidase (S15 family) K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 474.0
PYH3_k127_1405054_1 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000000000000000000000000047 126.0
PYH3_k127_1420775_0 DNA polymerase K02337 - 2.7.7.7 0.0 1139.0
PYH3_k127_1420775_1 Belongs to the IlvD Edd family K01690 - 4.2.1.12 2.381e-270 848.0
PYH3_k127_1420775_10 2-dehydro-3-deoxyphosphogluconate aldolase 4-hydroxy-2-oxoglutarate aldolase K01625 - 4.1.2.14,4.1.3.42 0.00000000000000000000000000000000000000000000000000000000000003765 222.0
PYH3_k127_1420775_11 Glycosyltransferase family 9 (heptosyltransferase) K02843 - - 0.0000000000000000000000000000000000000000000000000000000000002282 223.0
PYH3_k127_1420775_12 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000000003739 210.0
PYH3_k127_1420775_13 Glycosyltransferase family 25 (LPS biosynthesis protein) K07270 - - 0.00000000000000000000000000000000000000000000000000003789 196.0
PYH3_k127_1420775_2 ribonuclease, Rne Rng family K08301 - - 1.555e-223 700.0
PYH3_k127_1420775_3 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 7.161e-216 686.0
PYH3_k127_1420775_4 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 6.239e-205 650.0
PYH3_k127_1420775_5 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001781 571.0
PYH3_k127_1420775_6 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007767 357.0
PYH3_k127_1420775_7 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 322.0
PYH3_k127_1420775_8 COG0463 Glycosyltransferases involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 316.0
PYH3_k127_1420775_9 N-terminal domain of galactosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001566 297.0
PYH3_k127_142104_0 Belongs to the ABC transporter superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003751 447.0
PYH3_k127_142104_1 Diaminopropionate ammonia-lyase K01751 - 4.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 426.0
PYH3_k127_142104_2 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
PYH3_k127_1428166_0 histidine kinase A domain protein - - - 0.0 1329.0
PYH3_k127_1428166_1 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000005401 190.0
PYH3_k127_1428166_2 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000007403 113.0
PYH3_k127_1428166_3 - - - - 0.000000000000000005289 86.0
PYH3_k127_1438830_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 516.0
PYH3_k127_1438830_1 Nitrate reductase K00374 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006286 286.0
PYH3_k127_1438830_2 Nitrate reductase delta subunit K00373 - - 0.0000000000000000000000000000000000000000000003467 176.0
PYH3_k127_1438830_3 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000001863 156.0
PYH3_k127_1438830_4 Respiratory nitrate reductase beta C-terminal K00371 - 1.7.5.1 0.000000000000000000006986 92.0
PYH3_k127_1438830_5 NnrS protein K07234 - - 0.0000000000000000000471 95.0
PYH3_k127_144365_0 PFAM AAA ATPase central domain protein K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006884 437.0
PYH3_k127_144365_1 Histidine kinase K07673,K07674 GO:0000155,GO:0000160,GO:0001101,GO:0003674,GO:0003824,GO:0004672,GO:0004673,GO:0004721,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006468,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010167,GO:0016020,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016775,GO:0016787,GO:0016788,GO:0016791,GO:0018106,GO:0018193,GO:0018202,GO:0019538,GO:0023014,GO:0023052,GO:0033554,GO:0035556,GO:0036211,GO:0042221,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046777,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0065007,GO:0070887,GO:0071229,GO:0071241,GO:0071249,GO:0071250,GO:0071704,GO:0071944,GO:0080033,GO:0140096,GO:1901564,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008327 392.0
PYH3_k127_144365_10 PFAM Major facilitator superfamily K02575 - - 0.00000000000000001185 87.0
PYH3_k127_144365_2 TAP-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006353 375.0
PYH3_k127_144365_3 ABC-2 family transporter protein K09696 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001546 297.0
PYH3_k127_144365_4 ATPases associated with a variety of cellular activities K09697 - 3.6.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 295.0
PYH3_k127_144365_5 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001482 289.0
PYH3_k127_144365_6 Bacterial regulatory proteins, luxR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002505 242.0
PYH3_k127_144365_7 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000001829 227.0
PYH3_k127_144365_8 Protein tyrosine kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000006918 171.0
PYH3_k127_144365_9 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000002096 108.0
PYH3_k127_1447306_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1626.0
PYH3_k127_1447306_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 4.863e-239 746.0
PYH3_k127_1447306_10 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0019904,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:0097718,GO:0140096,GO:1901564 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 583.0
PYH3_k127_1447306_11 PFAM TRAP dicarboxylate transporter- DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 562.0
PYH3_k127_1447306_12 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000304 552.0
PYH3_k127_1447306_13 Integral membrane protein TerC family K05794 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008253 517.0
PYH3_k127_1447306_14 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 498.0
PYH3_k127_1447306_15 periplasmic K11688 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 483.0
PYH3_k127_1447306_16 Amidase K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000941 458.0
PYH3_k127_1447306_17 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003795 436.0
PYH3_k127_1447306_18 Methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004402 387.0
PYH3_k127_1447306_19 LysR substrate binding domain K13634 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001391 377.0
PYH3_k127_1447306_2 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 6.491e-225 699.0
PYH3_k127_1447306_20 Pfam Enoyl-CoA hydratase isomerase K11264 - 4.1.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 361.0
PYH3_k127_1447306_21 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007615 359.0
PYH3_k127_1447306_22 Predicted permease YjgP/YjgQ family K07091 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 336.0
PYH3_k127_1447306_23 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003415 321.0
PYH3_k127_1447306_24 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004615 321.0
PYH3_k127_1447306_25 Glyoxalase bleomycin resistance protein dioxygenase K08234 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 316.0
PYH3_k127_1447306_26 esterase K01432 - 3.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007251 319.0
PYH3_k127_1447306_27 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003973 282.0
PYH3_k127_1447306_28 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005605 269.0
PYH3_k127_1447306_29 Asp/Glu/Hydantoin racemase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003277 261.0
PYH3_k127_1447306_3 Trap dicarboxylate transporter, dctm subunit - - - 2.057e-224 700.0
PYH3_k127_1447306_30 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005404 260.0
PYH3_k127_1447306_31 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000136 248.0
PYH3_k127_1447306_32 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005946 253.0
PYH3_k127_1447306_33 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000001152 241.0
PYH3_k127_1447306_34 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000002658 214.0
PYH3_k127_1447306_35 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000000008476 205.0
PYH3_k127_1447306_36 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000000001047 203.0
PYH3_k127_1447306_37 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000000000000000001057 179.0
PYH3_k127_1447306_38 Plasmid stabilization system K19092 - - 0.000000000000000000000000000000000000000007529 159.0
PYH3_k127_1447306_39 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000003511 148.0
PYH3_k127_1447306_4 MmgE PrpD family protein - - - 1.505e-207 654.0
PYH3_k127_1447306_40 dna polymerase III (Chi subunit) K02339 - 2.7.7.7 0.00000000000000000000000000000003663 130.0
PYH3_k127_1447306_41 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000000000000000000000000000001566 126.0
PYH3_k127_1447306_42 PIN domain - - - 0.0000000000000000000000000000007552 126.0
PYH3_k127_1447306_43 Dodecin K09165 - - 0.00000000000000000000000000006342 118.0
PYH3_k127_1447306_44 YXWGXW repeat (2 copies) - - - 0.0000000000000000000000000015 115.0
PYH3_k127_1447306_45 - - - - 0.00000000000000000000000003967 113.0
PYH3_k127_1447306_46 - - - - 0.00000000000000000000003174 107.0
PYH3_k127_1447306_47 PFAM Uncharacterised protein family UPF0150 - - - 0.0000000000000000006149 91.0
PYH3_k127_1447306_48 Domain of unknown function (DUF4160) - - - 0.000000000000000008231 84.0
PYH3_k127_1447306_49 mRNA binding K07339 - - 0.00000000000000001443 87.0
PYH3_k127_1447306_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 2.25e-206 650.0
PYH3_k127_1447306_50 Protein of unknown function (DUF2783) - - - 0.0000000000000006719 79.0
PYH3_k127_1447306_51 Protein of unknown function (DUF2442) - - - 0.000000000000003879 78.0
PYH3_k127_1447306_53 Domain of unknown function (DUF4160) - - - 0.0000001962 52.0
PYH3_k127_1447306_55 - - - - 0.000004329 51.0
PYH3_k127_1447306_56 protein import - - - 0.00001675 50.0
PYH3_k127_1447306_57 - - - - 0.00002289 54.0
PYH3_k127_1447306_6 CoA-transferase family III K18289 - 2.8.3.22 1.681e-195 626.0
PYH3_k127_1447306_7 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005281 582.0
PYH3_k127_1447306_8 PFAM monooxygenase FAD-binding K05712 - 1.14.13.127 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008394 596.0
PYH3_k127_1447306_9 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 576.0
PYH3_k127_146729_0 Doubled CXXCH motif (Paired_CXXCH_1) - - - 1.606e-213 683.0
PYH3_k127_146729_1 Formyl transferase K19640 - - 1.381e-212 677.0
PYH3_k127_146729_10 NHL repeat - - - 0.000000000000009587 85.0
PYH3_k127_146729_11 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000001148 81.0
PYH3_k127_146729_12 PFAM UvrB UvrC protein - - - 0.000001354 59.0
PYH3_k127_146729_2 Belongs to the HypD family K04654 - - 1.163e-201 632.0
PYH3_k127_146729_3 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 533.0
PYH3_k127_146729_4 hydrogenase expression formation protein HypE K04655 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005764 522.0
PYH3_k127_146729_5 6-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 336.0
PYH3_k127_146729_6 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000007247 247.0
PYH3_k127_146729_7 low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000000000000000000000000000000000000000000000000007445 237.0
PYH3_k127_146729_8 transcriptional regulators K03892 - - 0.000000000000000000000000000000000000486 143.0
PYH3_k127_146729_9 - - - - 0.0000000000000000000001563 104.0
PYH3_k127_1504271_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 4.393e-289 895.0
PYH3_k127_1504271_1 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002978 352.0
PYH3_k127_1504271_10 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000001199 111.0
PYH3_k127_1504271_11 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.00000000000000000000007964 104.0
PYH3_k127_1504271_12 DsrE/DsrF-like family - - - 0.0000000000000000001808 93.0
PYH3_k127_1504271_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006295 269.0
PYH3_k127_1504271_3 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000196 248.0
PYH3_k127_1504271_4 Cytochrome c K17223 - - 0.000000000000000000000000000000000000000000000000000000000000000006252 231.0
PYH3_k127_1504271_5 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000006948 222.0
PYH3_k127_1504271_6 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000000000000000001182 190.0
PYH3_k127_1504271_7 oxidation protein K17227 - - 0.00000000000000000000000000000000000000003192 154.0
PYH3_k127_1504271_8 Thioredoxin-like - - - 0.00000000000000000000000000000000000001076 150.0
PYH3_k127_1504271_9 Peptidase S24-like - - - 0.000000000000000000000000000000004112 132.0
PYH3_k127_151570_0 SMP-30/Gluconolaconase/LRE-like region K14274 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009057 334.0
PYH3_k127_151570_1 of the drug metabolite transporter (DMT) superfamily K15270 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005018 267.0
PYH3_k127_151570_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000001313 244.0
PYH3_k127_151570_3 Alcohol dehydrogenase GroES-like domain K00001 - 1.1.1.1 0.000000000000000000000004144 102.0
PYH3_k127_152577_0 FAD dependent oxidoreductase - - - 1.444e-205 646.0
PYH3_k127_152577_1 Divergent 4Fe-4S mono-cluster - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 518.0
PYH3_k127_152577_2 Transposase domain (DUF772) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 473.0
PYH3_k127_152577_3 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 418.0
PYH3_k127_1547237_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 3.144e-209 671.0
PYH3_k127_1547237_1 Lanthionine synthetase C-like protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 508.0
PYH3_k127_1547237_10 PFAM OsmC family protein K04063 - - 0.000000000000000000000000000000000000000000000000174 181.0
PYH3_k127_1547237_11 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000003141 139.0
PYH3_k127_1547237_12 N-acetylmuramoyl-L-alanine amidase - - - 0.0000000000000000000000000000000001075 140.0
PYH3_k127_1547237_13 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000001014 136.0
PYH3_k127_1547237_14 - - - - 0.00000000000000000000001007 106.0
PYH3_k127_1547237_15 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000004325 98.0
PYH3_k127_1547237_16 Phosphotransferase System K11189 - - 0.0000000000000003634 82.0
PYH3_k127_1547237_17 SnoaL-like domain - - - 0.00000002788 62.0
PYH3_k127_1547237_18 SnoaL-like polyketide cyclase - - - 0.00000007044 56.0
PYH3_k127_1547237_2 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008642 405.0
PYH3_k127_1547237_20 - - - - 0.0003345 45.0
PYH3_k127_1547237_21 Protein of unknown function (DUF2934) - - - 0.0003671 48.0
PYH3_k127_1547237_3 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 362.0
PYH3_k127_1547237_4 PFAM NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005711 349.0
PYH3_k127_1547237_5 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009105 293.0
PYH3_k127_1547237_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K14583,K14751 - 1.13.11.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 292.0
PYH3_k127_1547237_7 Tryptophan-rich sensory protein K05770 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004349 264.0
PYH3_k127_1547237_8 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000001106 220.0
PYH3_k127_1547237_9 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000000005005 190.0
PYH3_k127_1587411_0 TIGRFAM rfaE bifunctional protein K03272,K21344 - 2.7.1.167,2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009206 411.0
PYH3_k127_1587411_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000263 368.0
PYH3_k127_1587411_2 Belongs to the mannose-6-phosphate isomerase type 2 family K00971,K16011 - 2.7.7.13,5.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000002024 260.0
PYH3_k127_1587411_3 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate - - - 0.0000000000000000000000000000000000000000000000000000000000008905 216.0
PYH3_k127_1587411_4 PIN domain - - - 0.00000000000000000000000000116 116.0
PYH3_k127_1587411_5 SpoVT / AbrB like domain - - - 0.00000000000332 70.0
PYH3_k127_1591316_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1149.0
PYH3_k127_1591316_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 483.0
PYH3_k127_1591316_2 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 355.0
PYH3_k127_1591316_3 ATPases associated with a variety of cellular activities K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001477 324.0
PYH3_k127_1591316_4 transporter, permease K02050,K15552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 305.0
PYH3_k127_1591316_5 TIGRFAM taurine ABC transporter, periplasmic binding protein K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 305.0
PYH3_k127_1591316_6 Selenocysteine synthase (Seryl-tRNASer selenium transferase) K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008065 288.0
PYH3_k127_1591316_7 Staphylococcal nuclease homologues - - - 0.00003865 49.0
PYH3_k127_1604910_0 Histidine kinase K02487,K06596 - - 0.0 1264.0
PYH3_k127_1604910_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 1.098e-285 883.0
PYH3_k127_1604910_10 D-Ala-D-Ala carboxypeptidase 3 (S13) family K07259 - 3.4.16.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 475.0
PYH3_k127_1604910_11 NADH:flavin oxidoreductase / NADH oxidase family K00354,K09461 - 1.14.13.40,1.6.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 466.0
PYH3_k127_1604910_12 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002505 393.0
PYH3_k127_1604910_13 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007113 397.0
PYH3_k127_1604910_14 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 367.0
PYH3_k127_1604910_15 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001389 340.0
PYH3_k127_1604910_16 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006416 336.0
PYH3_k127_1604910_17 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 318.0
PYH3_k127_1604910_18 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 304.0
PYH3_k127_1604910_19 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 292.0
PYH3_k127_1604910_2 intramolecular transferase activity, transferring amino groups K01845 - 5.4.3.8 1.456e-207 653.0
PYH3_k127_1604910_20 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006219 254.0
PYH3_k127_1604910_21 Lumazine binding domain K00793 - 2.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000001735 254.0
PYH3_k127_1604910_22 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000000000000000000000000000000000000000000001886 245.0
PYH3_k127_1604910_23 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.0000000000000000000000000000000000000000000000000000000000000000008424 231.0
PYH3_k127_1604910_24 Redoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000001636 230.0
PYH3_k127_1604910_25 Ribosomal protein S9/S16 K02996 - - 0.000000000000000000000000000000000000000000000000000000000000005225 219.0
PYH3_k127_1604910_26 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000007973 217.0
PYH3_k127_1604910_27 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000000000009918 219.0
PYH3_k127_1604910_28 cheY-homologous receiver domain K02657 - - 0.00000000000000000000000000000000000000000000000000000000000004054 215.0
PYH3_k127_1604910_29 PFAM OsmC family protein K07397 - - 0.000000000000000000000000000000000000000000000000000000000001152 214.0
PYH3_k127_1604910_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 606.0
PYH3_k127_1604910_30 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.00000000000000000000000000000000000000000000000000000000008887 208.0
PYH3_k127_1604910_31 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.00000000000000000000000000000000000000000000000000000006765 202.0
PYH3_k127_1604910_32 Phosphoglycerate mutase K15634 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000002899 197.0
PYH3_k127_1604910_33 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000003012 186.0
PYH3_k127_1604910_34 - - - - 0.00000000000000000000000000000000000000000000000000139 195.0
PYH3_k127_1604910_35 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000002496 184.0
PYH3_k127_1604910_36 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000002075 172.0
PYH3_k127_1604910_37 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000003627 177.0
PYH3_k127_1604910_38 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000001306 176.0
PYH3_k127_1604910_39 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000004619 164.0
PYH3_k127_1604910_4 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 562.0
PYH3_k127_1604910_40 Integral membrane protein CcmA involved in cell shape determination - - - 0.0000000000000000000000000000000000225 139.0
PYH3_k127_1604910_41 CheW-like domain K02659 - - 0.0000000000000000000000000000001958 130.0
PYH3_k127_1604910_42 PFAM Rubredoxin-type Fe(Cys)4 protein - - - 0.00000000000000000000000000000442 119.0
PYH3_k127_1604910_43 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000001054 121.0
PYH3_k127_1604910_44 Hsp20/alpha crystallin family - - - 0.0000000000000000000000002526 110.0
PYH3_k127_1604910_45 CAAX protease self-immunity K07052 - - 0.000000000000000000001775 104.0
PYH3_k127_1604910_46 CRISPR_assoc - - - 0.00001269 55.0
PYH3_k127_1604910_47 Prokaryotic cytochrome b561 K12262 - - 0.0008381 44.0
PYH3_k127_1604910_5 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 576.0
PYH3_k127_1604910_6 Disulphide bond corrector protein DsbC K04084,K08344 - 1.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 545.0
PYH3_k127_1604910_7 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002218 521.0
PYH3_k127_1604910_8 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004026 484.0
PYH3_k127_1604910_9 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 476.0
PYH3_k127_1613913_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1024.0
PYH3_k127_1613913_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 8.319e-318 982.0
PYH3_k127_1613913_10 Imidazolone-5-propionate hydrolase K01468 - 3.5.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 345.0
PYH3_k127_1613913_11 Pfam:AmoA K07120 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 333.0
PYH3_k127_1613913_12 COG0451 Nucleoside-diphosphate-sugar epimerases K05281 - 1.3.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001435 331.0
PYH3_k127_1613913_13 Hydrolases of the alpha beta superfamily K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 292.0
PYH3_k127_1613913_14 FR47-like protein - - - 0.0000000000000000000000000000000000000000000000000000000004383 211.0
PYH3_k127_1613913_15 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.0000000000000000000000000000000000000000000000000003058 192.0
PYH3_k127_1613913_16 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.000000000000000000000000000000000000000000000000005013 184.0
PYH3_k127_1613913_17 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000000000000000001099 185.0
PYH3_k127_1613913_18 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000000178 163.0
PYH3_k127_1613913_19 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000003927 142.0
PYH3_k127_1613913_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.452e-282 873.0
PYH3_k127_1613913_20 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000437 127.0
PYH3_k127_1613913_21 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000001144 111.0
PYH3_k127_1613913_22 ATP synthase I chain K02116 - - 0.00000000000000000408 88.0
PYH3_k127_1613913_23 Glucose / Sorbosone dehydrogenase - - - 0.0000000000007934 72.0
PYH3_k127_1613913_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 5.722e-275 850.0
PYH3_k127_1613913_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005279 423.0
PYH3_k127_1613913_5 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000168 418.0
PYH3_k127_1613913_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003722 394.0
PYH3_k127_1613913_7 Amidohydrolase family K05603 - 3.5.3.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 398.0
PYH3_k127_1613913_8 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002733 387.0
PYH3_k127_1613913_9 Belongs to the ParB family K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 348.0
PYH3_k127_164055_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1478.0
PYH3_k127_164055_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 1.467e-245 765.0
PYH3_k127_164055_2 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006807 286.0
PYH3_k127_164055_3 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003218 280.0
PYH3_k127_164055_4 Psort location Extracellular, score - - - 0.0000000000000000000000000221 118.0
PYH3_k127_164055_5 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000000003205 108.0
PYH3_k127_164055_6 Cysteine-rich secretory protein family - - - 0.00000000000000000000008583 106.0
PYH3_k127_164055_7 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.0000000000000000000003154 98.0
PYH3_k127_164055_8 MlaD protein K02067 - - 0.0000000000007996 79.0
PYH3_k127_164055_9 - - - - 0.0005382 51.0
PYH3_k127_1711812_0 Ferredoxin--NADP reductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003726 584.0
PYH3_k127_1711812_1 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 441.0
PYH3_k127_1711812_10 Phospholipid methyltransferase - - - 0.0000000000000000002513 98.0
PYH3_k127_1711812_11 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 0.0000000003326 62.0
PYH3_k127_1711812_2 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 436.0
PYH3_k127_1711812_3 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 411.0
PYH3_k127_1711812_4 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 305.0
PYH3_k127_1711812_5 Ornithine cyclodeaminase/mu-crystallin family K01750 - 4.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006598 310.0
PYH3_k127_1711812_6 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001478 299.0
PYH3_k127_1711812_7 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000001117 250.0
PYH3_k127_1711812_8 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000007521 246.0
PYH3_k127_1711812_9 Protein of unknown function (DUF2946) - - - 0.000000000000000000000000000000000000000009299 163.0
PYH3_k127_1727173_0 Dienelactone hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 439.0
PYH3_k127_1727173_1 COG3436 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 414.0
PYH3_k127_1727173_10 HicA toxin of bacterial toxin-antitoxin, - - - 0.0000000007493 62.0
PYH3_k127_1727173_2 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.00000000000000000000000000000000000000000001714 162.0
PYH3_k127_1727173_3 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system K09803 - - 0.000000000000000000000000000000104 126.0
PYH3_k127_1727173_4 - - - - 0.000000000000000000000000002836 112.0
PYH3_k127_1727173_5 Protein of unknown function (DUF2283) - - - 0.000000000000000000000002838 104.0
PYH3_k127_1727173_6 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000481 102.0
PYH3_k127_1727173_7 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000002608 94.0
PYH3_k127_1727173_8 BrnA antitoxin of type II toxin-antitoxin system - - - 0.00000000001595 72.0
PYH3_k127_1727173_9 copG family - - - 0.0000000001697 65.0
PYH3_k127_1739605_0 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004234 566.0
PYH3_k127_1739605_1 TIGRFAM glycine betaine L-proline ABC transporter, ATPase subunit K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003506 380.0
PYH3_k127_1739605_2 ABC-type proline glycine betaine transport K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000239 269.0
PYH3_k127_1739605_3 Binding-protein-dependent transport system inner membrane component K05845,K05846 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000709 264.0
PYH3_k127_1816910_0 peptidase M24 K01262 - 3.4.11.9 7.404e-258 808.0
PYH3_k127_1816910_1 PGAP1-like protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 458.0
PYH3_k127_1816910_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003284 269.0
PYH3_k127_1816910_11 Chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000000000003817 245.0
PYH3_k127_1816910_12 Histidine kinase K07648 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000007761 259.0
PYH3_k127_1816910_13 chromate transporter K07240 - - 0.00000000000000000000000000000000000000000000000000000000000000001209 237.0
PYH3_k127_1816910_14 Beta-lactamase - - - 0.00000000000000000000000000000000000005493 148.0
PYH3_k127_1816910_15 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001698 136.0
PYH3_k127_1816910_16 Cold shock K03704 - - 0.000000000000000000000000009522 109.0
PYH3_k127_1816910_17 RsgA GTPase K06949 - 3.1.3.100 0.000001536 51.0
PYH3_k127_1816910_18 - - - - 0.00002471 48.0
PYH3_k127_1816910_2 PFAM glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 412.0
PYH3_k127_1816910_3 DeoC/LacD family aldolase K11645 GO:0003674,GO:0003824,GO:0004332,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016829,GO:0016830,GO:0016832,GO:0042802,GO:0044424,GO:0044444,GO:0044464 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002586 395.0
PYH3_k127_1816910_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 396.0
PYH3_k127_1816910_5 EamA-like transporter family K05786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006205 377.0
PYH3_k127_1816910_6 Trypsin-like peptidase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 383.0
PYH3_k127_1816910_7 helix_turn_helix multiple antibiotic resistance protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006077 374.0
PYH3_k127_1816910_8 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 317.0
PYH3_k127_1816910_9 Methyladenine glycosylase K01246 - 3.2.2.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 299.0
PYH3_k127_1839493_0 transport systems, ATPase components K02056 - 3.6.3.17 7.104e-260 809.0
PYH3_k127_1839493_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002856 514.0
PYH3_k127_1839493_2 Xanthine dehydrogenase accessory protein XdhC K07402 - - 0.000000000000000000000000000000000001878 140.0
PYH3_k127_1899337_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1317.0
PYH3_k127_1899337_1 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1279.0
PYH3_k127_1899337_10 Tat pathway signal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 311.0
PYH3_k127_1899337_11 Divalent heavy-metal cations transporter K16267 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006012 289.0
PYH3_k127_1899337_12 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000000000000000000009911 212.0
PYH3_k127_1899337_13 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000513 201.0
PYH3_k127_1899337_14 Tat pathway signal - - - 0.00000000000000000000000000000000000000000005133 177.0
PYH3_k127_1899337_15 Sulfurtransferase K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000004357 156.0
PYH3_k127_1899337_16 ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000002444 141.0
PYH3_k127_1899337_17 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000005343 155.0
PYH3_k127_1899337_18 Transposase K07499 - - 0.00000000000000000000000000001309 124.0
PYH3_k127_1899337_19 - - - - 0.00000000000000000000000000009869 125.0
PYH3_k127_1899337_2 DNA helicase K03657 - 3.6.4.12 5.073e-281 899.0
PYH3_k127_1899337_20 DDE superfamily endonuclease - - - 0.0000000000000000000000000004646 122.0
PYH3_k127_1899337_21 Ion channel - - - 0.00000000000000000000001509 105.0
PYH3_k127_1899337_22 Peptidase family M1 domain - - - 0.00000000000000000321 90.0
PYH3_k127_1899337_23 Protein of unknown function (DUF1800) - - - 0.00000294 51.0
PYH3_k127_1899337_3 Putative modulator of DNA gyrase - - - 6.232e-200 633.0
PYH3_k127_1899337_4 PFAM peptidase S8 and S53, subtilisin, kexin, sedolisin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 609.0
PYH3_k127_1899337_5 Putative modulator of DNA gyrase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003937 471.0
PYH3_k127_1899337_6 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 387.0
PYH3_k127_1899337_7 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006318 341.0
PYH3_k127_1899337_8 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 333.0
PYH3_k127_1899337_9 Protein of unknown function (DUF1800) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 319.0
PYH3_k127_1902589_0 Histidine kinase-like ATPases - - - 1.93e-320 1067.0
PYH3_k127_190504_0 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.08e-260 810.0
PYH3_k127_190504_1 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 556.0
PYH3_k127_190504_2 Protein tyrosine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 425.0
PYH3_k127_190504_3 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 338.0
PYH3_k127_190504_4 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001209 337.0
PYH3_k127_190504_5 Domain of unknown function (DUF1732) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 313.0
PYH3_k127_190504_6 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 294.0
PYH3_k127_190504_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000002189 251.0
PYH3_k127_190504_8 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.00000000000000000000000000263 112.0
PYH3_k127_1965940_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1250.0
PYH3_k127_1965940_1 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003777 565.0
PYH3_k127_1965940_10 HAD-superfamily hydrolase, subfamily IB (PSPase-like) - - - 0.000000000000000000000000000000000000000000000000000000000000000199 227.0
PYH3_k127_1965940_11 Aminotransferase K03430 - 2.6.1.37 0.000000000000000000000000000000000000000000000000000005823 198.0
PYH3_k127_1965940_12 Cupin domain - - - 0.0000000000000000000000000000000000000000000000000001235 193.0
PYH3_k127_1965940_13 Belongs to the DnaA family K10763 - - 0.0000000000000000000000000000000000000000000000000007956 194.0
PYH3_k127_1965940_14 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.0000000000000000000000000000000000000005685 154.0
PYH3_k127_1965940_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 519.0
PYH3_k127_1965940_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004395 454.0
PYH3_k127_1965940_4 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 435.0
PYH3_k127_1965940_5 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 362.0
PYH3_k127_1965940_6 Pfam:UPF0118 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003917 349.0
PYH3_k127_1965940_7 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 348.0
PYH3_k127_1965940_8 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004814 299.0
PYH3_k127_1965940_9 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 298.0
PYH3_k127_2033694_0 - - - - 0.0000000000000000000000000000000000000000000000000000000006443 215.0
PYH3_k127_2033694_1 Conserved Protein - - - 0.00000000000000000000000000000000000884 149.0
PYH3_k127_2033694_2 Fatty acid cis/trans isomerase (CTI) - - - 0.000000000000000003949 85.0
PYH3_k127_2033694_4 META domain - - - 0.0000205 56.0
PYH3_k127_2067158_0 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 334.0
PYH3_k127_2067158_1 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000009389 218.0
PYH3_k127_2178973_0 Acyclic terpene utilisation family protein AtuA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 557.0
PYH3_k127_2178973_1 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001732 436.0
PYH3_k127_2178973_2 Amino-transferase class IV - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 351.0
PYH3_k127_2178973_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005008 298.0
PYH3_k127_2178973_4 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002494 258.0
PYH3_k127_2178973_5 SOUL heme-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001117 237.0
PYH3_k127_2178973_6 COGs COG1569 nucleic acid-binding protein contains PIN domain - - - 0.000000000000000000000000000000000000000000003943 167.0
PYH3_k127_2178973_7 - - - - 0.0000000000000000000000000000000000001576 147.0
PYH3_k127_2178973_8 PFAM SpoVT AbrB - - - 0.000000000000000000000000000006833 120.0
PYH3_k127_2218611_0 Activates fatty acids by binding to coenzyme A K01897 - 6.2.1.3 3.299e-215 682.0
PYH3_k127_2218611_1 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 1.084e-202 645.0
PYH3_k127_2218611_10 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005237 269.0
PYH3_k127_2218611_11 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005835 252.0
PYH3_k127_2218611_12 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000001623 183.0
PYH3_k127_2218611_13 Helix-turn-helix domain - - - 0.00000000000000000000000001475 115.0
PYH3_k127_2218611_14 Aspartyl protease K06985 - - 0.00000000000000003952 93.0
PYH3_k127_2218611_2 Bacterial pre-peptidase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003812 569.0
PYH3_k127_2218611_3 Phage integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002771 517.0
PYH3_k127_2218611_4 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 400.0
PYH3_k127_2218611_5 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 377.0
PYH3_k127_2218611_6 ABC transporter K02028 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008229 344.0
PYH3_k127_2218611_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 300.0
PYH3_k127_2218611_8 Bacterial periplasmic substrate-binding proteins K02030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 291.0
PYH3_k127_2218611_9 amino acid ABC transporter K02029 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007759 286.0
PYH3_k127_2277504_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004533 598.0
PYH3_k127_2277504_1 DNA polymerase III (Delta subunit) K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 350.0
PYH3_k127_2277504_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 317.0
PYH3_k127_2277504_3 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.0000000000000000000000000000000000000000002505 164.0
PYH3_k127_2277504_4 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 GO:0003674,GO:0003824,GO:0004812,GO:0004823,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006429,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.4 0.0000007245 51.0
PYH3_k127_22812_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 539.0
PYH3_k127_22812_1 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000003518 249.0
PYH3_k127_2282462_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K18138 - - 0.0 1322.0
PYH3_k127_2282462_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 2.317e-277 879.0
PYH3_k127_2282462_10 succinylglutamate desuccinylase K06987 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 409.0
PYH3_k127_2282462_11 PFAM ABC transporter related K10017,K10025 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 367.0
PYH3_k127_2282462_12 Ligated ion channel L-glutamate- and glycine-binding site - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 336.0
PYH3_k127_2282462_13 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005805 331.0
PYH3_k127_2282462_14 PFAM Methyltransferase type 11 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005963 315.0
PYH3_k127_2282462_15 Helix-turn-helix domain, rpiR family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
PYH3_k127_2282462_16 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K01069 - 3.1.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003925 297.0
PYH3_k127_2282462_17 Binding-protein-dependent transport system inner membrane component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 292.0
PYH3_k127_2282462_18 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005792 295.0
PYH3_k127_2282462_19 Binding-protein-dependent transport system inner membrane component K02029,K10019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006932 271.0
PYH3_k127_2282462_2 Peptidase C39 family K13409 - - 1.225e-205 664.0
PYH3_k127_2282462_20 Glycosyl transferases group 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004664 269.0
PYH3_k127_2282462_21 HlyD family secretion protein K13408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003174 269.0
PYH3_k127_2282462_22 PFAM ABC transporter related K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000003134 249.0
PYH3_k127_2282462_23 PFAM pyridoxamine 5-phosphate K07006 - - 0.0000000000000000000000000000000000000000000000000000000000000000001557 241.0
PYH3_k127_2282462_24 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000001312 225.0
PYH3_k127_2282462_25 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000001001 226.0
PYH3_k127_2282462_26 Glyoxalase bleomycin resistance - - - 0.0000000000000000000000000000000000000000000000000009705 185.0
PYH3_k127_2282462_27 enzyme binding - - - 0.000000000000000000000000000001065 127.0
PYH3_k127_2282462_28 Protein of unknown function (DUF1059) - - - 0.0000000000000000000000006435 106.0
PYH3_k127_2282462_29 - - - - 0.0000001623 53.0
PYH3_k127_2282462_3 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 600.0
PYH3_k127_2282462_4 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001584 544.0
PYH3_k127_2282462_5 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005685 516.0
PYH3_k127_2282462_6 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004881 496.0
PYH3_k127_2282462_7 Lytic transglycosylase K08307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009541 458.0
PYH3_k127_2282462_8 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001544 418.0
PYH3_k127_2282462_9 FtsX-like permease family K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006716 419.0
PYH3_k127_230982_0 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 2.42e-196 628.0
PYH3_k127_230982_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001645 274.0
PYH3_k127_230982_2 - - - - 0.00001017 47.0
PYH3_k127_2324762_0 AcrB/AcrD/AcrF family - - - 5.291e-308 962.0
PYH3_k127_2324762_1 Biotin-lipoyl like - - - 0.00000000000000000000000000000000000000003887 158.0
PYH3_k127_2330220_0 D-amino acid K00285 - 1.4.5.1 1.734e-210 659.0
PYH3_k127_2330220_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002082 572.0
PYH3_k127_2330220_10 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001933 328.0
PYH3_k127_2330220_11 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000009055 261.0
PYH3_k127_2330220_12 SCP-2 sterol transfer family - - - 0.000000000000000000000000000000000000000000000000000000001496 206.0
PYH3_k127_2330220_13 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000002446 199.0
PYH3_k127_2330220_15 COG0112 Glycine serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000001848 168.0
PYH3_k127_2330220_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K16871 - 2.6.1.96 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000182 572.0
PYH3_k127_2330220_3 PFAM extracellular solute-binding protein family 1 K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 528.0
PYH3_k127_2330220_4 Catalyzes the formation of 2-oxobutanoate from L-threonine or the formation of pyruvate from serine K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 481.0
PYH3_k127_2330220_5 Binding-protein-dependent transport system inner membrane component K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004719 450.0
PYH3_k127_2330220_6 COG4638 Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit K00499,K16319 - 1.14.12.1,1.14.15.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 431.0
PYH3_k127_2330220_7 ROK family K00847 - 2.7.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 400.0
PYH3_k127_2330220_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052,K11072,K11076 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 398.0
PYH3_k127_2330220_9 binding-protein-dependent transport systems inner membrane component K02053 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005103 359.0
PYH3_k127_2334144_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1138.0
PYH3_k127_2334144_1 ABC transporter transmembrane region K06147 - - 4.67e-265 828.0
PYH3_k127_2334144_10 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 525.0
PYH3_k127_2334144_11 PFAM ABC transporter related K02028,K09972 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003942 449.0
PYH3_k127_2334144_12 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 436.0
PYH3_k127_2334144_13 acid transport system permease K09970 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009283 388.0
PYH3_k127_2334144_14 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 381.0
PYH3_k127_2334144_15 3-deoxy-D-manno-oct-2-ulosonic acid (Kdo) hydroxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 355.0
PYH3_k127_2334144_16 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 351.0
PYH3_k127_2334144_17 COG3293 Transposase and inactivated derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000106 276.0
PYH3_k127_2334144_18 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001726 282.0
PYH3_k127_2334144_19 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000008709 273.0
PYH3_k127_2334144_2 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 1.209e-252 791.0
PYH3_k127_2334144_20 Protein of unknown function (DUF3025) - - - 0.000000000000000000000000000000000000000000000000000000000000000002083 235.0
PYH3_k127_2334144_22 Thioesterase superfamily K10806 - - 0.0000000000000000000000000000000000000000000000000000000187 199.0
PYH3_k127_2334144_23 AsnC family transcriptional regulator K03719 - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
PYH3_k127_2334144_24 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000002668 184.0
PYH3_k127_2334144_25 - - - - 0.0000000000000000000000000000000000000000007047 166.0
PYH3_k127_2334144_26 Histidine kinase - - - 0.000000000000000000000000000000001766 133.0
PYH3_k127_2334144_27 Role in flagellar biosynthesis K02421 - - 0.0000000000000000000000000000000078 133.0
PYH3_k127_2334144_28 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.000000000000000000000000000001291 131.0
PYH3_k127_2334144_29 flagellar protein FliS K02422 - - 0.000000000000000000000000000002619 125.0
PYH3_k127_2334144_3 Outer membrane protein beta-barrel family K02014 - - 7.44e-214 689.0
PYH3_k127_2334144_30 cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000001047 93.0
PYH3_k127_2334144_31 Flagellar protein FliT K02423 - - 0.000000000000000001987 92.0
PYH3_k127_2334144_32 Aldo/keto reductase family - - - 0.0000000000000009428 78.0
PYH3_k127_2334144_33 - - - - 0.00000000000002327 82.0
PYH3_k127_2334144_34 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000000004225 72.0
PYH3_k127_2334144_35 Membrane - - - 0.00000000001531 74.0
PYH3_k127_2334144_36 Acts as a flagellar brake, regulating swimming and swarming in a bis-(3'-5') cyclic diguanylic acid (c-di-GMP)- dependent manner. Binds 1 c-di-GMP dimer per subunit. Increasing levels of c-di-GMP lead to decreased motility - - - 0.00000000007652 72.0
PYH3_k127_2334144_37 Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end K02407 - - 0.000000001619 63.0
PYH3_k127_2334144_38 Flagellar regulator YcgR - - - 0.00000002731 64.0
PYH3_k127_2334144_39 Flagellar hook-length control protein FliK - - - 0.0004623 46.0
PYH3_k127_2334144_4 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 3.259e-199 629.0
PYH3_k127_2334144_5 Cys/Met metabolism PLP-dependent enzyme K01739,K01758,K01760,K01761 - 2.5.1.48,4.4.1.1,4.4.1.11,4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 604.0
PYH3_k127_2334144_6 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 578.0
PYH3_k127_2334144_7 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000779 580.0
PYH3_k127_2334144_8 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 546.0
PYH3_k127_2334144_9 extracellular solute-binding protein, family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005184 543.0
PYH3_k127_2371493_0 cellulase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009994 289.0
PYH3_k127_2392430_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 570.0
PYH3_k127_2392430_1 aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518,K04107 - 1.2.5.3,1.3.7.9 0.000000000000000000000000000000000000000000000000000000000000000000001091 242.0
PYH3_k127_2392430_2 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K03520,K04108 - 1.2.5.3,1.3.7.9 0.000000000000000000000000000000000000000000000000000000181 201.0
PYH3_k127_2392430_3 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000002207 53.0
PYH3_k127_2409412_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 4.759e-258 820.0
PYH3_k127_2409412_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 4.083e-215 680.0
PYH3_k127_2409412_10 (ABC) transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 381.0
PYH3_k127_2409412_11 Transcriptional regulator, LysR family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 334.0
PYH3_k127_2409412_12 2-Keto-4-pentenoate hydratase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 307.0
PYH3_k127_2409412_13 Glyoxalase-like domain K06996 - - 0.00000000000000000000000000000000000000000000000000000000001122 208.0
PYH3_k127_2409412_14 hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000001115 132.0
PYH3_k127_2409412_15 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.000000000000000000000000000001636 121.0
PYH3_k127_2409412_16 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000002495 105.0
PYH3_k127_2409412_17 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000002089 102.0
PYH3_k127_2409412_18 Phosphopantetheine attachment site - - - 0.000000000000000005392 94.0
PYH3_k127_2409412_19 membrane - - - 0.000000001312 64.0
PYH3_k127_2409412_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001636 554.0
PYH3_k127_2409412_20 - - - - 0.000004923 53.0
PYH3_k127_2409412_3 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007378 539.0
PYH3_k127_2409412_4 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 526.0
PYH3_k127_2409412_5 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004291 503.0
PYH3_k127_2409412_6 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 503.0
PYH3_k127_2409412_7 e3 binding domain K00627 - 2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004687 457.0
PYH3_k127_2409412_8 Bacterial protein of unknown function (DUF885) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 432.0
PYH3_k127_2409412_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 392.0
PYH3_k127_2440260_0 Sodium/hydrogen exchanger family K03455,K11745,K11747 - - 1.425e-266 833.0
PYH3_k127_2440260_1 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000251 283.0
PYH3_k127_2440260_2 NADPH-quinone reductase (modulator of drug activity B) K00355,K11746,K11748 - 1.6.5.2 0.00000000000000000000000000000000000000000000000000000000000000003864 227.0
PYH3_k127_2440260_3 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000000000000000000000000000000221 205.0
PYH3_k127_2440260_4 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000004459 199.0
PYH3_k127_2454170_0 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 5.641e-289 908.0
PYH3_k127_2454170_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.518e-231 730.0
PYH3_k127_2454170_10 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 441.0
PYH3_k127_2454170_11 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 431.0
PYH3_k127_2454170_12 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 387.0
PYH3_k127_2454170_13 Mediates influx of magnesium ions K03284 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006694 368.0
PYH3_k127_2454170_14 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007967 337.0
PYH3_k127_2454170_15 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004034 335.0
PYH3_k127_2454170_16 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000633 333.0
PYH3_k127_2454170_17 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003116 305.0
PYH3_k127_2454170_18 ABC-2 type transporter K09694 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006105 293.0
PYH3_k127_2454170_19 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001246 277.0
PYH3_k127_2454170_2 type IV pilus secretin PilQ K02666 - - 1.108e-230 739.0
PYH3_k127_2454170_20 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001425 261.0
PYH3_k127_2454170_21 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002696 248.0
PYH3_k127_2454170_22 Pilus assembly protein, PilO K02664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005632 248.0
PYH3_k127_2454170_23 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001151 246.0
PYH3_k127_2454170_24 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.0000000000000000000000000000000000000000000000000000000000000000007582 230.0
PYH3_k127_2454170_25 PFAM cytochrome c, class I - - - 0.000000000000000000000000000000000000000000000000000000000000000001744 238.0
PYH3_k127_2454170_26 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000227 228.0
PYH3_k127_2454170_27 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.00000000000000000000000000000000000000000000000000000000000000003222 224.0
PYH3_k127_2454170_28 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000002898 226.0
PYH3_k127_2454170_29 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000000000003528 213.0
PYH3_k127_2454170_3 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006404 540.0
PYH3_k127_2454170_30 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000001489 208.0
PYH3_k127_2454170_31 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000000000566 200.0
PYH3_k127_2454170_32 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000001357 192.0
PYH3_k127_2454170_33 Fimbrial assembly protein (PilN) K02663 - - 0.0000000000000000000000000000000000000000000000000002329 191.0
PYH3_k127_2454170_34 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000000000003706 197.0
PYH3_k127_2454170_35 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000004068 177.0
PYH3_k127_2454170_36 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000007431 169.0
PYH3_k127_2454170_37 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000001503 166.0
PYH3_k127_2454170_38 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000000007947 167.0
PYH3_k127_2454170_39 Pilus assembly protein, PilP K02665 - - 0.0000000000000000000000000000000000000000001482 166.0
PYH3_k127_2454170_4 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 528.0
PYH3_k127_2454170_40 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000000000000000000000000000000000003194 150.0
PYH3_k127_2454170_41 Redoxin domain protein - - - 0.000000000000000000000000000000000000001623 153.0
PYH3_k127_2454170_42 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.000000000000000000000000000000000000006185 147.0
PYH3_k127_2454170_43 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000000004856 145.0
PYH3_k127_2454170_44 S4 RNA-binding domain - - - 0.0000000000000000000000000000000000009591 144.0
PYH3_k127_2454170_45 Belongs to the frataxin family K06202 - - 0.0000000000000000000000000000000004626 133.0
PYH3_k127_2454170_46 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000000000008779 131.0
PYH3_k127_2454170_47 PFAM CutA1 divalent ion tolerance protein K03926 GO:0003674,GO:0005488,GO:0005507,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914 - 0.00000000000000000000000000000006508 130.0
PYH3_k127_2454170_48 Large extracellular alpha-helical protein - - - 0.00000000000000000003073 106.0
PYH3_k127_2454170_49 Ribosomal protein L30 K02907 - - 0.00000000000000000009195 90.0
PYH3_k127_2454170_5 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 527.0
PYH3_k127_2454170_50 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000001755 83.0
PYH3_k127_2454170_51 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000002176 73.0
PYH3_k127_2454170_52 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000002828 72.0
PYH3_k127_2454170_6 Catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and in maintaining the intracellular balance of A and G nucleotides K00364 - 1.7.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 467.0
PYH3_k127_2454170_7 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008402 460.0
PYH3_k127_2454170_8 Type IV pilus assembly protein PilM; K02662 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 456.0
PYH3_k127_2454170_9 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K09695 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 453.0
PYH3_k127_2460854_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 518.0
PYH3_k127_2460854_1 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 515.0
PYH3_k127_2460854_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 438.0
PYH3_k127_2460854_3 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001523 371.0
PYH3_k127_2460854_4 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 329.0
PYH3_k127_2460854_5 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 288.0
PYH3_k127_2467412_0 Aminotransferase K00375 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006702 568.0
PYH3_k127_2467412_1 TIGRFAM taurine ABC transporter, periplasmic binding protein K15551 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 508.0
PYH3_k127_2467412_2 ABC transporter K10831 - 3.6.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 464.0
PYH3_k127_2467412_3 PFAM binding-protein-dependent transport systems inner membrane component K02050,K15552 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 451.0
PYH3_k127_2467412_4 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002626 451.0
PYH3_k127_2468491_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 8.374e-264 834.0
PYH3_k127_2468491_1 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 2.581e-231 727.0
PYH3_k127_2468491_10 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000000000004587 188.0
PYH3_k127_2468491_11 helix_turn_helix, mercury resistance - - - 0.0000000000000000000000000000000000000000000000001616 179.0
PYH3_k127_2468491_12 PFAM Lysine exporter protein (LYSE YGGA) - - - 0.00000000000000000000000000000000000000000000001234 185.0
PYH3_k127_2468491_13 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000005639 148.0
PYH3_k127_2468491_14 ASCH - - - 0.000000000000000000000000000000000004329 144.0
PYH3_k127_2468491_15 Tellurite resistance protein TerB - - - 0.000000000000000000000000000000000007164 142.0
PYH3_k127_2468491_16 Uncharacterized protein conserved in bacteria (DUF2332) K01056 - 3.1.1.29 0.00000000003332 68.0
PYH3_k127_2468491_17 Galactose binding lectin domain - - - 0.0000002656 58.0
PYH3_k127_2468491_18 DnaJ domain protein - - - 0.0004557 49.0
PYH3_k127_2468491_2 dehydrogenase K00253 - 1.3.8.4 3.921e-222 692.0
PYH3_k127_2468491_3 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 8.807e-222 706.0
PYH3_k127_2468491_4 Iron-containing alcohol dehydrogenase K00043,K00217 - 1.1.1.61,1.3.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004913 500.0
PYH3_k127_2468491_5 Zn-dependent hydrolases including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 443.0
PYH3_k127_2468491_6 abc transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008029 411.0
PYH3_k127_2468491_7 cystathionine beta-lyase K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002459 415.0
PYH3_k127_2468491_8 threonine dehydratase K17989 GO:0003674,GO:0003824,GO:0003941,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005829,GO:0006082,GO:0006090,GO:0006520,GO:0006563,GO:0006565,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009069,GO:0009071,GO:0009987,GO:0016053,GO:0016054,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0019842,GO:0030170,GO:0032787,GO:0036094,GO:0042802,GO:0042803,GO:0042866,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046395,GO:0046983,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0072330,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901605,GO:1901606 4.3.1.17,4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 367.0
PYH3_k127_2468491_9 Thioesterase superfamily - - - 0.000000000000000000000000000000000000000000000000000000001382 205.0
PYH3_k127_2476664_0 - - - - 0.000000000000000000000000000000000000000000000000000000001939 225.0
PYH3_k127_2476664_1 Prolyl 4-hydroxylase alpha subunit homologues. K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000004195 168.0
PYH3_k127_2476664_2 - - - - 0.000008001 58.0
PYH3_k127_2495905_0 Nickel-dependent hydrogenase K06281 - 1.12.99.6 3.21e-321 989.0
PYH3_k127_2495905_1 TIGRFAM hydrogenase (NiFe) small subunit HydA K06282 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.12.99.6 1.666e-206 647.0
PYH3_k127_2495905_2 Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism K21053 - 3.5.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003169 458.0
PYH3_k127_2495905_3 Succinylglutamate desuccinylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 334.0
PYH3_k127_2495905_4 N-formylglutamate amidohydrolase K01458 - 3.5.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000001526 278.0
PYH3_k127_2495905_5 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000001164 178.0
PYH3_k127_2495905_6 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000003516 109.0
PYH3_k127_2510799_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 5.941e-247 782.0
PYH3_k127_2510799_1 B12 binding domain - - - 1.249e-208 666.0
PYH3_k127_2510799_10 Outer membrane protein beta-barrel domain - - - 0.0000000000000001415 88.0
PYH3_k127_2510799_11 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00003292 49.0
PYH3_k127_2510799_2 Belongs to the bacterial glucokinase family K00845 - 2.7.1.2 3.888e-205 653.0
PYH3_k127_2510799_3 gluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005092 368.0
PYH3_k127_2510799_4 PFAM extracellular solute-binding protein family 3 K02030,K09969,K10001 - - 0.0000000000000000000000000000000000000000000000000000000000000004589 231.0
PYH3_k127_2510799_5 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000009764 217.0
PYH3_k127_2510799_6 N-acetyltransferase K00675 - 2.3.1.118 0.00000000000000000000000000000003666 137.0
PYH3_k127_2510799_7 NHL repeat - - - 0.0000000000000000000000000000007144 121.0
PYH3_k127_2510799_8 amine dehydrogenase activity K13730 - - 0.000000000000000000000000000213 128.0
PYH3_k127_2510799_9 - - - - 0.000000000000000000005699 104.0
PYH3_k127_2512165_0 PFAM CHAD domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000595 235.0
PYH3_k127_2512165_1 Domain of unknown function DUF302 - - - 0.000000000000000000000000000000000000000000000000000005979 192.0
PYH3_k127_2512165_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000006802 138.0
PYH3_k127_2512165_3 - - - - 0.0000000000000001495 81.0
PYH3_k127_2512553_0 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 1.881e-219 691.0
PYH3_k127_2512553_1 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 7.962e-201 643.0
PYH3_k127_2512553_10 SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000005264 235.0
PYH3_k127_2512553_11 PFAM Secreted repeat of - - - 0.000000000000000000000000000000000000000000000000005347 188.0
PYH3_k127_2512553_12 WHG domain - - - 0.000000000000000000000000000000000000000000000001516 181.0
PYH3_k127_2512553_13 DsrE/DsrF-like family - - - 0.000000000000000000000000000000000000000000005968 170.0
PYH3_k127_2512553_14 atpase or kinase K06925 - - 0.00000000000000000000000000000000000000000004052 167.0
PYH3_k127_2512553_15 nuclease K01174 - 3.1.31.1 0.000000000000000000418 90.0
PYH3_k127_2512553_16 diguanylate cyclase - - - 0.0000000000000001706 89.0
PYH3_k127_2512553_2 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 479.0
PYH3_k127_2512553_3 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000577 476.0
PYH3_k127_2512553_4 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 471.0
PYH3_k127_2512553_5 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 356.0
PYH3_k127_2512553_6 Major facilitator superfamily K07552,K18552 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 334.0
PYH3_k127_2512553_7 Transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002343 302.0
PYH3_k127_2512553_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 304.0
PYH3_k127_2512553_9 Membrane transport protein K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001917 252.0
PYH3_k127_2559798_0 DEAD-like helicases superfamily - - - 0.0 1012.0
PYH3_k127_2559798_1 COG0553 Superfamily II DNA RNA helicases, SNF2 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 582.0
PYH3_k127_2561771_0 aminopeptidase N K01256 - 3.4.11.2 5.048e-303 947.0
PYH3_k127_2561771_1 PFAM transposase, IS4 family protein - - - 3.875e-286 887.0
PYH3_k127_2561771_2 Belongs to the glutaminase family K01425 - 3.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 498.0
PYH3_k127_2561771_3 - - - - 0.00000000004619 74.0
PYH3_k127_2561771_4 Outer membrane efflux protein - - - 0.000002665 57.0
PYH3_k127_2566129_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 5.369e-302 940.0
PYH3_k127_2566129_1 membrane - - - 0.00000000000000000000000000003981 117.0
PYH3_k127_259680_0 Hydrogenase K04652 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 427.0
PYH3_k127_259680_1 PFAM HupH hydrogenase expression protein K03618 - - 0.000000000000000000000000000000000000000000000000000000000000000000111 240.0
PYH3_k127_259680_2 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.0000000000000000000000000000000000000000000000000000000001019 207.0
PYH3_k127_259680_3 Ni,Fe-hydrogenase I large subunit - - - 0.000000000000000000000000000000000000000000000000000004868 205.0
PYH3_k127_259680_4 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009898,GO:0010467,GO:0016020,GO:0016151,GO:0019538,GO:0019897,GO:0019898,GO:0031234,GO:0043167,GO:0043169,GO:0043170,GO:0044238,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046872,GO:0046914,GO:0051604,GO:0071704,GO:0071944,GO:0098552,GO:0098562,GO:1901564 - 0.000000000000000000000000000000000000001261 150.0
PYH3_k127_259680_5 [NiFe]-hydrogenase assembly, chaperone, HybE - - - 0.00000000000000000000000000000000002056 143.0
PYH3_k127_259680_6 Hydrogenase expression formation protein K03605 - - 0.0000000000000000000000000000000005689 135.0
PYH3_k127_259680_7 Rubredoxin - - - 0.000000000000000000000000000001235 123.0
PYH3_k127_259680_8 Hydrogenase-1 expression protein HyaE K03619 - - 0.00000000000000000000000000168 118.0
PYH3_k127_259680_9 Hydrogenase expression formation protein (HUPF HYPC) K04653 - - 0.0000000000000000000000006636 108.0
PYH3_k127_2607363_0 H( )-stimulated, divalent metal cation uptake system - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004192 461.0
PYH3_k127_2607363_1 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000002289 196.0
PYH3_k127_2607363_2 Sulfur transfer protein involved in thiamine biosynthesis K03154 - - 0.00000000000000001238 84.0
PYH3_k127_2607363_3 Nitroreductase family K09019 - - 0.000000001476 61.0
PYH3_k127_2611628_0 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 4.091e-314 967.0
PYH3_k127_2611628_1 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 2.357e-242 751.0
PYH3_k127_2611628_2 ArgK protein K07588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004375 515.0
PYH3_k127_2612078_0 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000001584 235.0
PYH3_k127_2612078_1 Transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000004587 222.0
PYH3_k127_2612078_2 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00000000000000000000000000000000000000001523 153.0
PYH3_k127_2612078_3 PFAM Integrase catalytic - - - 0.0000000000000000000000000000000000226 143.0
PYH3_k127_2612078_4 Sigma-70 region 2 - - - 0.0000000157 58.0
PYH3_k127_2612078_5 YCII-related domain - - - 0.00004977 55.0
PYH3_k127_2619764_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.153e-215 685.0
PYH3_k127_2619764_1 PFAM type II secretion system K02455,K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 395.0
PYH3_k127_2619764_2 general secretion pathway protein G K02456 - - 0.0000000000000000000000000000000000000000000000000000000000002661 215.0
PYH3_k127_2622048_0 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0 1135.0
PYH3_k127_2622048_1 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 6.19e-243 771.0
PYH3_k127_2622048_2 Decaheme c-type cytochrome, DmsE family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 430.0
PYH3_k127_2622048_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003028 364.0
PYH3_k127_2622048_4 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000287 275.0
PYH3_k127_2622048_5 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000000000000000000000000000001242 227.0
PYH3_k127_2622048_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000009344 50.0
PYH3_k127_263193_0 Tricorn protease homolog K08676 - - 0.0 1104.0
PYH3_k127_263193_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.0 1019.0
PYH3_k127_263193_10 Cysteine-rich domain - - - 1.989e-211 664.0
PYH3_k127_263193_100 - - - - 0.000000000000000000008952 98.0
PYH3_k127_263193_101 Putative polyhydroxyalkanoic acid system protein (PHA_gran_rgn) - - - 0.00000000000000001207 86.0
PYH3_k127_263193_102 - - - - 0.0000000000004358 72.0
PYH3_k127_263193_103 Receptor family ligand binding region K01999 - - 0.0000000005468 67.0
PYH3_k127_263193_104 Protein conserved in bacteria K09705 - - 0.000000003839 64.0
PYH3_k127_263193_106 RDD family - - - 0.00005287 50.0
PYH3_k127_263193_11 Branched-chain amino acid transport system / permease component K01997,K01998 - - 3.723e-211 672.0
PYH3_k127_263193_12 Oxidoreductase - - - 4.331e-206 653.0
PYH3_k127_263193_13 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 6.349e-203 640.0
PYH3_k127_263193_14 ABC-type Fe3 transport system, periplasmic component - - - 5.145e-196 620.0
PYH3_k127_263193_15 TRAP-type C4-dicarboxylate transport system, large permease - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006018 620.0
PYH3_k127_263193_16 Extracellular liganD-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009275 601.0
PYH3_k127_263193_17 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 592.0
PYH3_k127_263193_18 VWA domain containing CoxE-like protein K09989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002876 577.0
PYH3_k127_263193_19 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 550.0
PYH3_k127_263193_2 Acetyl-coenzyme A synthetase N-terminus K01908 - 6.2.1.17 0.0 1018.0
PYH3_k127_263193_20 TIGRFAM acetylornithine and succinylornithine aminotransferase K00819,K00821 GO:0003674,GO:0005488,GO:0005515,GO:0008144,GO:0019842,GO:0030170,GO:0036094,GO:0042802,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0070279,GO:0097159,GO:1901363 2.6.1.11,2.6.1.13,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 546.0
PYH3_k127_263193_21 CAAX prenyl protease N-terminal, five membrane helices K06013 - 3.4.24.84 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009655 525.0
PYH3_k127_263193_22 Domain of unknown function (DUF3488) K22452 - 2.3.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006896 537.0
PYH3_k127_263193_23 transporter K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 518.0
PYH3_k127_263193_24 Transcriptional regulator with HTH domain and aminotransferase domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002089 511.0
PYH3_k127_263193_25 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007808 499.0
PYH3_k127_263193_26 Vacuole effluxer Atg22 like K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 497.0
PYH3_k127_263193_27 ATPase associated with various cellular activities, AAA_5 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003963 487.0
PYH3_k127_263193_28 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 483.0
PYH3_k127_263193_29 Electron transfer flavoprotein, alpha subunit K03522 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009171 475.0
PYH3_k127_263193_3 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 0.0 1015.0
PYH3_k127_263193_30 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003898 473.0
PYH3_k127_263193_31 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003504 474.0
PYH3_k127_263193_32 Elongator protein 3, MiaB family, Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008864 444.0
PYH3_k127_263193_33 Bacterial extracellular solute-binding protein K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 436.0
PYH3_k127_263193_34 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs K05825 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 433.0
PYH3_k127_263193_35 Patatin-like phospholipase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000902 430.0
PYH3_k127_263193_36 histone deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008803 418.0
PYH3_k127_263193_37 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 417.0
PYH3_k127_263193_38 Electron transfer flavoprotein K03521 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009224 412.0
PYH3_k127_263193_39 beta' subunit K01754 - 4.3.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008305 405.0
PYH3_k127_263193_4 Male sterility protein - - - 0.0 1005.0
PYH3_k127_263193_40 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 398.0
PYH3_k127_263193_41 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain, D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015,K00090 - 1.1.1.215,1.1.1.26,1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 366.0
PYH3_k127_263193_42 fumarylacetoacetate (FAA) hydrolase K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007656 356.0
PYH3_k127_263193_43 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004439 357.0
PYH3_k127_263193_44 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 345.0
PYH3_k127_263193_45 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004713 323.0
PYH3_k127_263193_46 Oxidoreductase NAD-binding domain K00528 - 1.18.1.2,1.19.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005399 324.0
PYH3_k127_263193_47 Threonyl alanyl tRNA synthetase K07050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 326.0
PYH3_k127_263193_48 Patatin-like phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 319.0
PYH3_k127_263193_49 Bacterial transcriptional repressor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 319.0
PYH3_k127_263193_5 Molecular chaperone. Has ATPase activity K04079 - - 1.266e-298 927.0
PYH3_k127_263193_50 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 302.0
PYH3_k127_263193_51 Diguanylate cyclase with PAS PAC and GAF sensors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 309.0
PYH3_k127_263193_52 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009122 288.0
PYH3_k127_263193_53 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit K06949 - 3.1.3.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006196 293.0
PYH3_k127_263193_54 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007428 293.0
PYH3_k127_263193_55 PFAM glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007586 279.0
PYH3_k127_263193_56 Peptidase_C39 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006482 277.0
PYH3_k127_263193_57 maleylacetoacetate isomerase K01800,K01801 - 5.2.1.2,5.2.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000001189 287.0
PYH3_k127_263193_58 Glycosyltransferase like family 2 K20534 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001569 269.0
PYH3_k127_263193_59 LUD domain K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001766 269.0
PYH3_k127_263193_6 Oxidizes proline to glutamate for use as a carbon and nitrogen source K13821 - 1.2.1.88,1.5.5.2 1.509e-288 919.0
PYH3_k127_263193_60 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000278 265.0
PYH3_k127_263193_61 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004861 268.0
PYH3_k127_263193_62 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001306 263.0
PYH3_k127_263193_63 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001791 256.0
PYH3_k127_263193_64 Part of a membrane complex involved in electron transport K03616 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006058 252.0
PYH3_k127_263193_65 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001079 249.0
PYH3_k127_263193_66 Spermidine synthase K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000004204 251.0
PYH3_k127_263193_67 phosphorelay sensor kinase activity K02342,K02851 - 2.7.7.7,2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000000000000000000000000000004442 254.0
PYH3_k127_263193_68 lytic murein transglycosylase K08305 - - 0.00000000000000000000000000000000000000000000000000000000000000000000007351 253.0
PYH3_k127_263193_69 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.00000000000000000000000000000000000000000000000000000000000000000002599 244.0
PYH3_k127_263193_7 PFAM Acyl-CoA dehydrogenase N terminal, Acyl-CoA dehydrogenase, C-terminal domain, Acyl-CoA dehydrogenase, middle domain, Acyl-CoA dehydrogenase, N-terminal domain K20035 - - 1.607e-277 864.0
PYH3_k127_263193_70 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000003643 245.0
PYH3_k127_263193_71 Nudix hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001126 241.0
PYH3_k127_263193_72 PFAM Phenazine biosynthesis PhzC PhzF protein K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000005184 244.0
PYH3_k127_263193_73 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000007115 240.0
PYH3_k127_263193_74 glycosylase K03649 - 3.2.2.28 0.0000000000000000000000000000000000000000000000000000000000000009104 222.0
PYH3_k127_263193_75 ABC-type branched-chain amino acid transport systems ATPase component K01996 - - 0.000000000000000000000000000000000000000000000000000000000000004228 224.0
PYH3_k127_263193_76 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.00000000000000000000000000000000000000000000000000000000005407 207.0
PYH3_k127_263193_77 Bacterial protein of unknown function (DUF924) - - - 0.0000000000000000000000000000000000000000000000000000000002359 209.0
PYH3_k127_263193_78 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.000000000000000000000000000000000000000000000000000000006733 199.0
PYH3_k127_263193_79 Haem-degrading K11477 - - 0.000000000000000000000000000000000000000000000000000002238 195.0
PYH3_k127_263193_8 PFAM AMP-dependent synthetase and ligase K00666 - - 5.726e-271 842.0
PYH3_k127_263193_80 COG3706 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000001242 201.0
PYH3_k127_263193_81 Protein of unknown function (DUF1631) - - - 0.000000000000000000000000000000000000000000000000004192 206.0
PYH3_k127_263193_82 Domain of unknown function (DUF1841) - - - 0.0000000000000000000000000000000000000000000000005958 181.0
PYH3_k127_263193_83 DUF218 domain - - - 0.00000000000000000000000000000000000000000000001783 181.0
PYH3_k127_263193_84 Lrp/AsnC ligand binding domain - - - 0.000000000000000000000000000000000000000000001277 171.0
PYH3_k127_263193_85 NLP P60 protein - - - 0.0000000000000000000000000000000000000002 158.0
PYH3_k127_263193_86 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.0000000000000000000000000000000000000002889 156.0
PYH3_k127_263193_87 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000001758 153.0
PYH3_k127_263193_88 PFAM poly granule associated family protein - - - 0.000000000000000000000000000000000000002323 152.0
PYH3_k127_263193_89 Pterin 4 alpha carbinolamine dehydratase K01724 - 4.2.1.96 0.000000000000000000000000000000000000009548 147.0
PYH3_k127_263193_9 ABC-type Fe3 transport system permease component K02011 - - 2.159e-250 788.0
PYH3_k127_263193_90 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000000000000009058 143.0
PYH3_k127_263193_91 membrane - - - 0.0000000000000000000000000000000000008998 150.0
PYH3_k127_263193_92 Copper resistance protein D - - - 0.0000000000000000000000000000000001429 137.0
PYH3_k127_263193_93 acyl-coA-binding protein - - - 0.000000000000000000000000000000000322 134.0
PYH3_k127_263193_94 Cytochrome c - - - 0.00000000000000000000000000003538 121.0
PYH3_k127_263193_95 lactoylglutathione lyase activity K08234 - - 0.0000000000000000000000000001563 120.0
PYH3_k127_263193_96 Cytochrome c, class I - - - 0.0000000000000000000000000002593 117.0
PYH3_k127_263193_97 - - - - 0.000000000000000000000004775 111.0
PYH3_k127_263193_98 Putative prokaryotic signal transducing protein - - - 0.00000000000000000000000546 113.0
PYH3_k127_263193_99 TM2 domain - - - 0.000000000000000000003841 97.0
PYH3_k127_2639706_0 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000648 512.0
PYH3_k127_2639706_1 Nitronate monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 502.0
PYH3_k127_2639706_10 Tellurite resistance protein TehB - - - 0.0000000000000000000000000000000000000000000000000000000000000000001188 237.0
PYH3_k127_2639706_11 PFAM BLUF domain protein - - - 0.000000000000000000000000000000000000000000000000000000003957 210.0
PYH3_k127_2639706_12 NADP oxidoreductase coenzyme F420-dependent K06988 - 1.5.1.40 0.00000000000000000000000000000000000000000000000000000001473 203.0
PYH3_k127_2639706_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004369 433.0
PYH3_k127_2639706_3 GTP cyclohydrolase I K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002655 386.0
PYH3_k127_2639706_4 Serine hydroxymethyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 379.0
PYH3_k127_2639706_5 DJ-1/PfpI family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005767 351.0
PYH3_k127_2639706_6 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009626 346.0
PYH3_k127_2639706_7 Oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001459 342.0
PYH3_k127_2639706_8 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 304.0
PYH3_k127_2639706_9 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000009173 257.0
PYH3_k127_2650488_0 nucleotidyltransferase activity - - - 0.000000000000000000000000000000001911 142.0
PYH3_k127_2650488_1 - - - - 0.000000000000000000003314 96.0
PYH3_k127_2650488_2 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000001631 65.0
PYH3_k127_2656285_0 Ribosomal RNA adenine dimethylase - - - 0.000000000000000000000000000000000000000000000000000000000000000168 228.0
PYH3_k127_2656285_1 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000002726 154.0
PYH3_k127_2656285_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.000000000000000000000002283 105.0
PYH3_k127_2656285_3 Protein of unknown function (DUF2788) - - - 0.000000000000000000000005637 104.0
PYH3_k127_267865_0 Protein of unknown function (DUF3604) - - - 0.0 1021.0
PYH3_k127_267865_1 PPIC-type PPIASE domain - - - 0.00000000000000000000000000000000000000000000000000000000000001514 225.0
PYH3_k127_267865_2 long-chain fatty acid transport protein - - - 0.0000000000000000000000000000000000000000003432 164.0
PYH3_k127_267865_4 - - - - 0.00000000000000000000000000009021 124.0
PYH3_k127_2700596_0 GTP-binding protein K06207 - - 3.833e-309 957.0
PYH3_k127_2700596_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.746e-254 790.0
PYH3_k127_2700596_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 333.0
PYH3_k127_2700596_3 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000000000000000002619 164.0
PYH3_k127_2714460_0 Transposase for insertion sequences IS1326 IS1353 (IS21 IS408 IS1162 family protein) - - - 1.065e-195 622.0
PYH3_k127_2714460_1 IstB-like ATP binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 326.0
PYH3_k127_2714460_2 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 300.0
PYH3_k127_2714460_3 - - - - 0.0000000000000000000000000008992 117.0
PYH3_k127_2714460_5 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.00000000000000000004643 99.0
PYH3_k127_2714763_0 Extracellular ligand-binding receptor K01999 - - 5.002e-203 638.0
PYH3_k127_2714763_1 Aldehyde dehydrogenase family K00294 - 1.2.1.88 3.647e-200 638.0
PYH3_k127_2714763_10 s cog2930 - - - 0.000000000000001004 77.0
PYH3_k127_2714763_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 494.0
PYH3_k127_2714763_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003209 471.0
PYH3_k127_2714763_4 PFAM ABC transporter related K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 381.0
PYH3_k127_2714763_5 Lysozyme inhibitor LprI - - - 0.000000000000000000000000000000000000000000000000000000000000004557 228.0
PYH3_k127_2714763_6 Thioesterase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001816 211.0
PYH3_k127_2714763_7 Type IV pili methyl-accepting chemotaxis transducer N-term - - - 0.00000000000000000000000000000000000000000000000000000000006058 216.0
PYH3_k127_2714763_8 - - - - 0.0000000000000000000000000000000000000000000002917 180.0
PYH3_k127_2714763_9 - - - - 0.0000000000000000000000000000000004175 143.0
PYH3_k127_2717286_0 orn lys arg decarboxylase K01583 - 4.1.1.19 0.0 1374.0
PYH3_k127_2717286_1 Protein of unknown function (DUF3141) - - - 0.0 1068.0
PYH3_k127_2717286_10 Coenzyme A transferase K01035 - 2.8.3.8,2.8.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001748 346.0
PYH3_k127_2717286_11 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007109 336.0
PYH3_k127_2717286_12 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004819 291.0
PYH3_k127_2717286_13 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000000000001017 194.0
PYH3_k127_2717286_14 Protein of unknown function (DUF3047) - - - 0.000000000000000000000000000000000000000000000001235 183.0
PYH3_k127_2717286_15 long-chain fatty acid transport protein - - - 0.000000000002971 72.0
PYH3_k127_2717286_16 - - - - 0.00000001472 55.0
PYH3_k127_2717286_17 COG3385 FOG Transposase and inactivated derivatives - - - 0.0000314 48.0
PYH3_k127_2717286_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 556.0
PYH3_k127_2717286_3 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 551.0
PYH3_k127_2717286_4 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003481 537.0
PYH3_k127_2717286_5 phosphate K00625 - 2.3.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 507.0
PYH3_k127_2717286_6 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 440.0
PYH3_k127_2717286_7 AI-2E family transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004299 407.0
PYH3_k127_2717286_8 TIGRFAM 3-hydroxybutyrate dehydrogenase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 388.0
PYH3_k127_2717286_9 Predicted membrane protein (DUF2254) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008155 351.0
PYH3_k127_2733811_0 - - - - 0.00000000000000000000000000000000000000002455 156.0
PYH3_k127_2733811_1 Transposase K07483 - - 0.0000000000000000000000000000000000001549 146.0
PYH3_k127_2733811_2 TonB-dependent Receptor Plug Domain K02014 - - 0.000000000000001175 76.0
PYH3_k127_2733811_3 IS66 Orf2 like protein - - - 0.000000000000001391 81.0
PYH3_k127_2733811_4 - - - - 0.00007093 47.0
PYH3_k127_2750404_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 3.427e-287 897.0
PYH3_k127_2750404_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.4.1.4 2.407e-279 882.0
PYH3_k127_2750404_10 Domain of unknown function (DUF4126) - - - 0.0000000000000000000000000000000000000000000000000000000000000003022 227.0
PYH3_k127_2750404_11 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000000000000000000000000000000000000000000002533 183.0
PYH3_k127_2750404_12 dienelactone hydrolase - - - 0.000000000000000000000000000000000000000000000000885 190.0
PYH3_k127_2750404_13 Small Multidrug Resistance protein K03297 - - 0.000000000000000000000000000000000001095 145.0
PYH3_k127_2750404_14 Nucleotidyltransferase domain K07076 - - 0.00000000000000000000000001508 113.0
PYH3_k127_2750404_15 PFAM Small Multidrug Resistance protein K03297 - - 0.00000000000000000000003446 109.0
PYH3_k127_2750404_16 PFAM Pyruvate carboxyltransferase K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000001436 92.0
PYH3_k127_2750404_17 Bacterial antitoxin of type II TA system, VapB - - - 0.0000000000000000000265 93.0
PYH3_k127_2750404_18 HEPN domain - - - 0.00000000000000005126 87.0
PYH3_k127_2750404_19 LemA family - - - 0.00000000006319 66.0
PYH3_k127_2750404_2 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 3.195e-259 817.0
PYH3_k127_2750404_20 thiolester hydrolase activity K17362 - - 0.0000000001172 68.0
PYH3_k127_2750404_3 Acyl-CoA dehydrogenase, C-terminal domain K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002704 537.0
PYH3_k127_2750404_4 Sugar (and other) transporter K08151 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002629 437.0
PYH3_k127_2750404_5 Enoyl-CoA hydratase/isomerase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004937 327.0
PYH3_k127_2750404_6 PFAM D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding K12972 - 1.1.1.79,1.1.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000178 279.0
PYH3_k127_2750404_7 Carbonic anhydrase K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000001395 261.0
PYH3_k127_2750404_8 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000007471 251.0
PYH3_k127_2750404_9 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007962 242.0
PYH3_k127_2771889_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1055.0
PYH3_k127_2771889_1 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 1.074e-284 886.0
PYH3_k127_2771889_10 lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 558.0
PYH3_k127_2771889_11 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003943 527.0
PYH3_k127_2771889_12 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002566 373.0
PYH3_k127_2771889_13 Circularly permuted ATP-grasp type 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002593 337.0
PYH3_k127_2771889_14 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006748 301.0
PYH3_k127_2771889_15 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002373 291.0
PYH3_k127_2771889_16 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000003371 260.0
PYH3_k127_2771889_17 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005245 273.0
PYH3_k127_2771889_18 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000000000009227 244.0
PYH3_k127_2771889_19 transcriptional regulator, Rrf2 family K13643 - - 0.0000000000000000000000000000000000000000000000000000000000001082 221.0
PYH3_k127_2771889_2 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.859e-233 733.0
PYH3_k127_2771889_20 Belongs to the HesB IscA family K13628 - - 0.000000000000000000000000000000000000000000000000000004367 191.0
PYH3_k127_2771889_21 protein conserved in bacteria K09928 - - 0.0000000000000000000000000000000000000000000000000003387 190.0
PYH3_k127_2771889_22 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000006041 176.0
PYH3_k127_2771889_23 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000663 173.0
PYH3_k127_2771889_24 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000001676 175.0
PYH3_k127_2771889_25 NUDIX domain - - - 0.00000000000000000000000000000000000000000001667 175.0
PYH3_k127_2771889_26 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000003896 137.0
PYH3_k127_2771889_27 nitrogen regulatory protein P-II - - - 0.000000000000000000000000000004874 135.0
PYH3_k127_2771889_28 Fe-S assembly protein IscX - GO:0003674,GO:0004857,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0008150,GO:0008152,GO:0008198,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0030234,GO:0031163,GO:0043086,GO:0043167,GO:0043169,GO:0044085,GO:0044092,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050790,GO:0051186,GO:0065007,GO:0065009,GO:0071840,GO:0098772 - 0.000000000000000000000000009198 112.0
PYH3_k127_2771889_29 Diguanylate cyclase - - - 0.0000000000000000000003636 108.0
PYH3_k127_2771889_3 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.612e-227 706.0
PYH3_k127_2771889_4 single-stranded-DNA-specific exonuclease RecJ K07462 - - 3.165e-214 681.0
PYH3_k127_2771889_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 1.179e-210 678.0
PYH3_k127_2771889_6 Competence protein K02238 - - 6.955e-194 632.0
PYH3_k127_2771889_7 PFAM aminotransferase class I and II K00832 - 2.6.1.57 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 593.0
PYH3_k127_2771889_8 TIGRFAM acyltransferase, WS DGAT MGAT - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004437 599.0
PYH3_k127_2771889_9 Protein of unknown function (DUF1298) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 593.0
PYH3_k127_2774439_0 transposase - - - 0.00000000000000000000000000000000000000000000002516 173.0
PYH3_k127_2774439_1 Plasmid stabilization system K19092 - - 0.0000000000000000000000000001316 118.0
PYH3_k127_2774439_2 Ribbon-helix-helix protein, copG family - - - 0.0000000000000000007824 88.0
PYH3_k127_2844016_0 Bacterial NAD-glutamate dehydrogenase K15371 - 1.4.1.2 0.0 1709.0
PYH3_k127_2844016_1 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 3.378e-288 901.0
PYH3_k127_2844016_10 PFAM amidohydrolase 2 K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008599 469.0
PYH3_k127_2844016_11 Belongs to the peptidase S33 family K01259 - 3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008074 456.0
PYH3_k127_2844016_12 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000916 460.0
PYH3_k127_2844016_13 AMP-binding enzyme C-terminal domain K01911 - 6.2.1.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004073 432.0
PYH3_k127_2844016_14 PFAM amidohydrolase 2 K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006033 368.0
PYH3_k127_2844016_15 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 357.0
PYH3_k127_2844016_16 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003218 356.0
PYH3_k127_2844016_17 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
PYH3_k127_2844016_18 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006452 334.0
PYH3_k127_2844016_19 hydrolase K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008579 332.0
PYH3_k127_2844016_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.941e-251 783.0
PYH3_k127_2844016_20 Zn-dependent protease with chaperone function K07387 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 316.0
PYH3_k127_2844016_21 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 298.0
PYH3_k127_2844016_22 Nucleoside H+ symporter K05820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001785 296.0
PYH3_k127_2844016_23 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002154 267.0
PYH3_k127_2844016_24 Short-chain dehydrogenase reductase (SDR) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000003517 260.0
PYH3_k127_2844016_25 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004818 252.0
PYH3_k127_2844016_26 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007447 244.0
PYH3_k127_2844016_27 CBS domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000001517 234.0
PYH3_k127_2844016_28 Homocysteine S-methyltransferase K00548 - 2.1.1.13 0.000000000000000000000000000000000000000000000000000000000000000001391 238.0
PYH3_k127_2844016_29 FAD dependent oxidoreductase K06955 - - 0.000000000000000000000000000000000000000000000000000000000000000004746 238.0
PYH3_k127_2844016_3 Glycerol acyltransferase K05939 - 2.3.1.40,6.2.1.20 2.556e-240 759.0
PYH3_k127_2844016_30 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000002832 237.0
PYH3_k127_2844016_31 Lysine exporter protein (LYSE YGGA) - - - 0.000000000000000000000000000000000000000000000000000000000000008606 223.0
PYH3_k127_2844016_32 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000001988 227.0
PYH3_k127_2844016_33 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000002602 221.0
PYH3_k127_2844016_34 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.0000000000000000000000000000000000000000000000000000002814 196.0
PYH3_k127_2844016_35 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000006374 189.0
PYH3_k127_2844016_36 Receptor family ligand binding region - - - 0.000000000000000000000000000000000000000000003358 179.0
PYH3_k127_2844016_37 intradiol ring-cleavage dioxygenase K00449 - 1.13.11.3 0.0000000000000000000000000000000000000002681 159.0
PYH3_k127_2844016_38 LysM domain K08086 - - 0.00000000000000000000000000000000000006728 148.0
PYH3_k127_2844016_39 Entericidin EcnA/B family - - - 0.000000007859 57.0
PYH3_k127_2844016_4 Cyclohexanecarboxylate-CoA ligase K04116,K12507 - - 3.348e-221 699.0
PYH3_k127_2844016_40 ATPases associated with a variety of cellular activities K01996 - - 0.000009895 55.0
PYH3_k127_2844016_5 o-acetylhomoserine K01740 - 2.5.1.49 5.692e-217 679.0
PYH3_k127_2844016_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.85 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001241 594.0
PYH3_k127_2844016_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001641 582.0
PYH3_k127_2844016_8 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008749 572.0
PYH3_k127_2844016_9 Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA) K01661,K07536 - 4.1.3.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008975 516.0
PYH3_k127_286833_0 phenylacetic acid degradation protein paaN - - - 4.744e-257 804.0
PYH3_k127_286833_1 Phosphoglucomutase K15778 - 5.4.2.2,5.4.2.8 1.032e-214 675.0
PYH3_k127_286833_10 Phenylacetic acid degradation protein PaaY K02617 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005455 285.0
PYH3_k127_286833_11 O-Methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000000001182 271.0
PYH3_k127_286833_12 LysE type translocator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001057 262.0
PYH3_k127_286833_13 lipopolysaccharide heptosyltransferase I K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001326 265.0
PYH3_k127_286833_14 Bacterial transcriptional repressor C-terminal K09017 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000224 249.0
PYH3_k127_286833_15 phenylacetic acid degradation protein K02614 GO:0003674,GO:0003824,GO:0016289,GO:0016787,GO:0016788,GO:0016790 - 0.000000000000000000000000000000000000000000000004114 178.0
PYH3_k127_286833_16 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.00000000000000000000000000000000000001047 147.0
PYH3_k127_286833_17 PFAM Rhodanese domain protein - - - 0.00000000000000000000000000000000000001051 148.0
PYH3_k127_286833_18 Ribonuclease toxin, BrnT, of type II toxin-antitoxin system - - - 0.0000000000000000000000000003997 115.0
PYH3_k127_286833_19 - - - - 0.000000000000000001242 88.0
PYH3_k127_286833_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 1.605e-212 667.0
PYH3_k127_286833_20 Histidine kinase - - - 0.00000005056 62.0
PYH3_k127_286833_3 Phenylacetate-CoA oxygenase subunit PaaA K02609 - 1.14.13.149 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001728 584.0
PYH3_k127_286833_4 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002131 596.0
PYH3_k127_286833_5 transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 398.0
PYH3_k127_286833_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 380.0
PYH3_k127_286833_7 Belongs to the enoyl-CoA hydratase isomerase family K15866 - 5.3.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 369.0
PYH3_k127_286833_8 TIGRFAM type I secretion outer membrane protein, TolC family K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 368.0
PYH3_k127_286833_9 Phosphoglucose isomerase K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 347.0
PYH3_k127_2874613_0 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.725e-206 657.0
PYH3_k127_2874613_1 Alcohol dehydrogenase GroES-like domain K07538 - 1.1.1.368 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003796 531.0
PYH3_k127_2874613_2 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 418.0
PYH3_k127_2874613_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005158 396.0
PYH3_k127_2909053_0 arylsulfatase A K01130 - 3.1.6.1 1.036e-279 867.0
PYH3_k127_2909053_1 Cytochrome c554 and c-prime - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000117 629.0
PYH3_k127_2909053_2 response regulator - - - 0.00000000000008934 74.0
PYH3_k127_2918868_0 Bacterial regulatory protein, Fis family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 502.0
PYH3_k127_2918868_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001524 496.0
PYH3_k127_2918868_2 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000659 442.0
PYH3_k127_2918868_3 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003468 305.0
PYH3_k127_2918868_4 molybdopterin cofactor binding - - - 0.000000008401 60.0
PYH3_k127_2922661_0 - - - - 0.0000000000000000000000000000000000000000002477 165.0
PYH3_k127_2922661_1 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.00000000000000000000000000000000000000372 149.0
PYH3_k127_2922661_2 FeoA K04758 - - 0.0000000002122 66.0
PYH3_k127_2922661_3 Cytochrome C oxidase, cbb3-type, subunit III K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000001124 63.0
PYH3_k127_2948357_0 cytochrome - - - 0.00000000000000000000000005022 123.0
PYH3_k127_2948357_1 cytochrome K17230 - - 0.0000000000000002633 92.0
PYH3_k127_2948357_2 - - - - 0.000000005326 65.0
PYH3_k127_2953870_0 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 600.0
PYH3_k127_2953870_1 cytochrome - - - 0.0000000000000000000000000000000000000000000000000000000000000033 222.0
PYH3_k127_2953870_2 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.0000000000000000000000000009502 116.0
PYH3_k127_2953870_3 - - - - 0.00000000000000004343 87.0
PYH3_k127_2955778_0 COG3666 Transposase and inactivated derivatives - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 608.0
PYH3_k127_2955778_1 ParE toxin of type II toxin-antitoxin system, parDE K19092 - - 0.0000000000000000000000000000000000000006756 149.0
PYH3_k127_2955778_2 addiction module antidote protein, CC2985 family K07746 - - 0.00000000000000000000000000002035 119.0
PYH3_k127_3006497_0 Transposase DDE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001343 358.0
PYH3_k127_3006497_1 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006165 221.0
PYH3_k127_3006497_2 Histidine kinase - - - 0.00000000000000001273 83.0
PYH3_k127_3009384_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0 1041.0
PYH3_k127_3009384_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K13893 - - 2.418e-244 769.0
PYH3_k127_3009384_10 Bacterial regulatory helix-turn-helix protein, lysR family K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 330.0
PYH3_k127_3009384_11 Phage plasmid primase P4 family K06919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 325.0
PYH3_k127_3009384_12 Peptidase family M50 K06212,K06402 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0030312,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 327.0
PYH3_k127_3009384_13 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008968 258.0
PYH3_k127_3009384_14 Prokaryotic cytochrome b561 K12262 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000005363 236.0
PYH3_k127_3009384_15 Peptidyl-prolyl cis-trans K03775 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000008305 233.0
PYH3_k127_3009384_16 ribosomal large subunit export from nucleus - - - 0.0000000000000000000000000000000000000000000000000000000000000005068 223.0
PYH3_k127_3009384_17 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.00000000000000000000000000000000000000000000000000000000000000136 222.0
PYH3_k127_3009384_18 succinate dehydrogenase fumarate reductase, flavoprotein subunit K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000001912 195.0
PYH3_k127_3009384_19 - - - - 0.000000000000000000000000000000000000000003779 156.0
PYH3_k127_3009384_2 Belongs to the ABC transporter superfamily K02031,K02032,K13896 - - 4.411e-225 708.0
PYH3_k127_3009384_20 Nucleotidyltransferase domain K07075 - - 0.000000000000000000000000000000000000135 143.0
PYH3_k127_3009384_21 Transcriptional regulator K01420 - - 0.00000000000000000000000000000000000223 150.0
PYH3_k127_3009384_22 GYD domain - - - 0.0000000000000000000000000000000000258 138.0
PYH3_k127_3009384_23 - - - - 0.0000000000000000000000000000001586 130.0
PYH3_k127_3009384_24 Protein of unknown function DUF86 - - - 0.000000000000000000000000000003371 123.0
PYH3_k127_3009384_25 Protein of unknown function (DUF504) - - - 0.0000000000000000000000001008 109.0
PYH3_k127_3009384_26 - - - - 0.00000000000000001165 83.0
PYH3_k127_3009384_27 Protein required for attachment to host cells - - - 0.0000000000000001752 85.0
PYH3_k127_3009384_29 Transcriptional regulator - - - 0.0001273 45.0
PYH3_k127_3009384_3 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003208 586.0
PYH3_k127_3009384_4 PFAM binding-protein-dependent transport systems inner membrane component K13894 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002983 563.0
PYH3_k127_3009384_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07812 - 1.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 484.0
PYH3_k127_3009384_6 binding-protein-dependent transport systems inner membrane component K13895 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007739 477.0
PYH3_k127_3009384_7 AAA domain K07028 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000746 435.0
PYH3_k127_3009384_8 COG0733 Na -dependent transporters of the SNF family K03308 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 354.0
PYH3_k127_3009384_9 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 335.0
PYH3_k127_3043308_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.673e-300 936.0
PYH3_k127_3043308_1 AMP-binding enzyme K00666 - - 8.356e-298 924.0
PYH3_k127_3043308_10 Transcriptional regulator K04033 - - 0.00000000000000000000000000000000000000000000000000000000000000001216 237.0
PYH3_k127_3043308_11 enzyme related to lactoylglutathione lyase K06996 - - 0.0000000000000000000000000000000000000000001739 170.0
PYH3_k127_3043308_12 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000000000000000000000000000000000372 149.0
PYH3_k127_3043308_13 positive regulation of type IV pilus biogenesis K07343 - - 0.0000000000000000000001468 102.0
PYH3_k127_3043308_14 - - - - 0.0000000000000000000519 98.0
PYH3_k127_3043308_15 Domain of unknown function (DUF1330) - - - 0.00000000006321 67.0
PYH3_k127_3043308_16 Aspartyl Asparaginyl beta-hydroxylase K12979 - - 0.0009967 46.0
PYH3_k127_3043308_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K01426 - 3.5.1.4 4.582e-204 648.0
PYH3_k127_3043308_3 Aminotransferase class-III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000472 597.0
PYH3_k127_3043308_4 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003618 591.0
PYH3_k127_3043308_5 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 538.0
PYH3_k127_3043308_6 Histidine kinase K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003206 459.0
PYH3_k127_3043308_7 XdhC and CoxI family K07402 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002805 420.0
PYH3_k127_3043308_8 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 342.0
PYH3_k127_3043308_9 Transcriptional regulatory protein, C terminal K02483,K07666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003016 325.0
PYH3_k127_3109071_0 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003882 330.0
PYH3_k127_3109071_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003142 269.0
PYH3_k127_3141733_0 Diguanylate cyclase K13069 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0008270,GO:0009987,GO:0010639,GO:0016740,GO:0016772,GO:0016779,GO:0022610,GO:0031344,GO:0031345,GO:0031589,GO:0032879,GO:0033043,GO:0042710,GO:0042802,GO:0043167,GO:0043169,GO:0043708,GO:0043709,GO:0043900,GO:0043902,GO:0044010,GO:0044087,GO:0044464,GO:0044764,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0060187,GO:0060491,GO:0065007,GO:0090605,GO:0090609,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1902115,GO:1902116,GO:1902208,GO:1902209 2.7.7.65 0.00000000000000000000000000000000000003611 149.0
PYH3_k127_3141733_1 protein conserved in bacteria - - - 0.0000000000000000000000000000000195 131.0
PYH3_k127_3141733_2 Diguanylate cyclase K13069 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0007155,GO:0008150,GO:0008270,GO:0009987,GO:0010639,GO:0016740,GO:0016772,GO:0016779,GO:0022610,GO:0031344,GO:0031345,GO:0031589,GO:0032879,GO:0033043,GO:0042710,GO:0042802,GO:0043167,GO:0043169,GO:0043708,GO:0043709,GO:0043900,GO:0043902,GO:0044010,GO:0044087,GO:0044464,GO:0044764,GO:0046872,GO:0046914,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051270,GO:0051271,GO:0051704,GO:0052621,GO:0060187,GO:0060491,GO:0065007,GO:0090605,GO:0090609,GO:1900190,GO:1900192,GO:1900231,GO:1900233,GO:1902115,GO:1902116,GO:1902208,GO:1902209 2.7.7.65 0.000000000000000000000000001839 115.0
PYH3_k127_3141733_3 - - - - 0.00000000000000000000004315 101.0
PYH3_k127_3141733_4 carboxylic ester hydrolase activity K03929 - - 0.00000000005471 70.0
PYH3_k127_3157854_0 Catalyzes the conversion of L-lactate to pyruvate. Is coupled to the respiratory chain K00101 - 1.1.2.3 2.488e-211 661.0
PYH3_k127_3157854_1 Belongs to the peptidase M20A family. ArgE subfamily K01438 - 3.5.1.16 0.000000000000193 72.0
PYH3_k127_3157854_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000004772 53.0
PYH3_k127_3164838_0 TRAP dicarboxylate transporter, DctM subunit K03299 - - 1.508e-258 808.0
PYH3_k127_3164838_1 PFAM peptidase U62 modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004285 582.0
PYH3_k127_3164838_2 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000819 548.0
PYH3_k127_3164838_3 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 379.0
PYH3_k127_3164838_4 Molybdenum cofactor biosynthesis protein MogA K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 336.0
PYH3_k127_3164838_5 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002317 294.0
PYH3_k127_3164838_6 Tripartite ATP-independent periplasmic transporter DctQ - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008183 271.0
PYH3_k127_3164838_7 Belongs to the UPF0307 family K09889 - - 0.0000000000000000000000000000000000000000004069 163.0
PYH3_k127_3164838_8 PFAM DoxX family protein K15977 - - 0.00000000000000000000000000000000000003361 147.0
PYH3_k127_3191986_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 3201.0
PYH3_k127_3191986_1 Bacterial extracellular solute-binding protein K02027,K05813 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 589.0
PYH3_k127_3191986_10 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000000000000000005559 236.0
PYH3_k127_3191986_11 HNH nucleases - - - 0.0000000000000000000000000000000000000000000000000000001651 198.0
PYH3_k127_3191986_12 translation initiation inhibitor, yjgF family - - - 0.0000000000000000000000000000000000000000000000000000005099 196.0
PYH3_k127_3191986_13 Regulator K01420 - - 0.000000000000000000000000000000000000000000005755 177.0
PYH3_k127_3191986_14 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000003496 172.0
PYH3_k127_3191986_15 Rubrerythrin - - - 0.000000000000000000000000000000000000002313 154.0
PYH3_k127_3191986_17 - - - - 0.000000000000000000000000000001788 125.0
PYH3_k127_3191986_18 - - - - 0.000000000000000000000002281 108.0
PYH3_k127_3191986_19 7TM receptor with intracellular HD hydrolase - - - 0.0000000000000000000000664 102.0
PYH3_k127_3191986_2 Glycine/sarcosine/betaine reductase selenoprotein B (GRDB) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004392 471.0
PYH3_k127_3191986_20 - - - - 0.000000000000000006761 92.0
PYH3_k127_3191986_21 - - - - 0.000000000000009145 76.0
PYH3_k127_3191986_22 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000131 54.0
PYH3_k127_3191986_23 Belongs to the UPF0337 (CsbD) family - - - 0.0000002285 57.0
PYH3_k127_3191986_24 PFAM AMP-dependent synthetase and ligase - - - 0.0005623 44.0
PYH3_k127_3191986_3 COG3839 ABC-type sugar transport systems, ATPase components K05816 - 3.6.3.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009302 429.0
PYH3_k127_3191986_4 ABC-type sugar transport system, permease component K05815 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 426.0
PYH3_k127_3191986_5 PFAM binding-protein-dependent transport systems inner membrane component K02025,K05814,K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004199 406.0
PYH3_k127_3191986_6 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005757 370.0
PYH3_k127_3191986_7 Crp-like helix-turn-helix domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 360.0
PYH3_k127_3191986_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006164 291.0
PYH3_k127_3191986_9 Antibiotic biosynthesis monooxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000009121 241.0
PYH3_k127_3197170_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1026.0
PYH3_k127_3197170_1 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008689 248.0
PYH3_k127_3197170_2 Domain of unknown function (DUF4345) - - - 0.000000000000000000000001388 107.0
PYH3_k127_3236093_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 2.049e-206 690.0
PYH3_k127_3241215_0 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 452.0
PYH3_k127_3241215_1 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000001966 250.0
PYH3_k127_3241215_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.00000000000008181 74.0
PYH3_k127_3268310_0 PFAM CoA-binding domain protein K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007554 422.0
PYH3_k127_3268310_1 ATPase P-type (Transporting), HAD superfamily, subfamily IC K01535,K01537 - 3.6.3.6,3.6.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 294.0
PYH3_k127_3281163_0 Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations K01241 - 3.2.2.4 5.814e-262 813.0
PYH3_k127_3281163_1 PFAM binding-protein-dependent transport systems inner membrane component K02026 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 473.0
PYH3_k127_3281163_2 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000005062 70.0
PYH3_k127_3287072_0 PFAM Phosphoglucomutase phosphomannomutase, alpha beta alpha domain III, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain II, Phosphoglucomutase phosphomannomutase, C-terminal domain, Phosphoglucomutase phosphomannomutase, alpha beta alpha domain I K01835 - 5.4.2.2 8.329e-240 761.0
PYH3_k127_3287072_1 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 1.685e-207 651.0
PYH3_k127_3287072_10 metal cluster binding - - - 0.0000000000000000000009446 102.0
PYH3_k127_3287072_11 Sel1 domain protein repeat-containing protein K07126 - - 0.0000002846 61.0
PYH3_k127_3287072_2 Two component regulator propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001316 564.0
PYH3_k127_3287072_3 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 546.0
PYH3_k127_3287072_4 Two component regulator propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 510.0
PYH3_k127_3287072_5 response regulator K07714 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 340.0
PYH3_k127_3287072_6 ATPases associated with a variety of cellular activities K10112 - - 0.000000000000000000000000000000000000000000000000000000000001176 213.0
PYH3_k127_3287072_7 - - - - 0.00000000000000000000000000000000000000000000008941 175.0
PYH3_k127_3287072_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000001614 127.0
PYH3_k127_3287072_9 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000001656 109.0
PYH3_k127_3335971_0 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 0.0 1039.0
PYH3_k127_3335971_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 5.447e-296 929.0
PYH3_k127_3335971_2 Belongs to the glycosyl hydrolase 13 family K01214,K02438 - 3.2.1.196,3.2.1.68 1.001e-211 681.0
PYH3_k127_3335971_3 PFAM extracellular solute-binding protein family 1 K17315 - - 7.155e-199 627.0
PYH3_k127_3335971_4 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003615 563.0
PYH3_k127_3335971_5 Binding-protein-dependent transport system inner membrane component K17316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001334 496.0
PYH3_k127_3335971_6 Binding-protein-dependent transport system inner membrane component K17317 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 478.0
PYH3_k127_3335971_7 ABC transporter K10111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 446.0
PYH3_k127_3335971_8 ATPases associated with a variety of cellular activities K10112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004638 389.0
PYH3_k127_3335971_9 - - - - 0.0000000000000000000000000000000000000000001626 172.0
PYH3_k127_3372482_0 b-type cytochrome subunit K03620 GO:0003674,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006091,GO:0006113,GO:0008150,GO:0008152,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016021,GO:0020037,GO:0031224,GO:0031226,GO:0032991,GO:0044237,GO:0044425,GO:0044459,GO:0044464,GO:0044569,GO:0045333,GO:0046906,GO:0048037,GO:0055114,GO:0071944,GO:0097159,GO:1901363,GO:1902494 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002137 279.0
PYH3_k127_3372482_1 Hydrogenase maturation protease K03605 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 - 0.000000000000000000000000000000000001886 141.0
PYH3_k127_3372482_2 Helix-turn-helix K21498 - - 0.0000000000000000000002486 108.0
PYH3_k127_3391428_0 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 569.0
PYH3_k127_3391428_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000001287 220.0
PYH3_k127_3391428_2 - - - - 0.0000000000000000000000000000003211 126.0
PYH3_k127_3391428_3 MotA/TolQ/ExbB proton channel family - - - 0.00000000000000000006787 89.0
PYH3_k127_3414947_0 Bacterial transcriptional activator domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001995 287.0
PYH3_k127_3414947_1 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000004391 188.0
PYH3_k127_3414947_2 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000005178 119.0
PYH3_k127_3414947_3 - - - - 0.00002073 48.0
PYH3_k127_342547_0 TIGRFAM cytochrome C family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003456 498.0
PYH3_k127_342547_1 Doubled CXXCH motif (Paired_CXXCH_1) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000161 346.0
PYH3_k127_342547_2 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006381 322.0
PYH3_k127_342547_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 - 1.7.2.2 0.000000000000000000000000000000000000000000000000000007955 196.0
PYH3_k127_342547_4 NHL repeat - - - 0.000000000000000000000000000000001144 134.0
PYH3_k127_345386_0 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 3.476e-284 882.0
PYH3_k127_345386_1 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 5.967e-264 825.0
PYH3_k127_345386_2 formate dehydrogenase K00123 - 1.17.1.9 9.534e-258 799.0
PYH3_k127_345386_3 PFAM AMP-dependent synthetase and ligase K02182 - 6.2.1.48 3.411e-229 719.0
PYH3_k127_345386_4 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003173 511.0
PYH3_k127_345386_5 COG1840 ABC-type Fe3 transport system, periplasmic component K02012 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009199 451.0
PYH3_k127_345386_6 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 373.0
PYH3_k127_345386_7 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379,K18360 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000236 276.0
PYH3_k127_345386_8 NADH-dependant formate dehydrogenase delta subunit FdsD K00126 - 1.17.1.9 0.000000000000000000000008444 102.0
PYH3_k127_3565507_0 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000007535 222.0
PYH3_k127_3565507_1 small integral membrane protein - - - 0.0000000000000007643 78.0
PYH3_k127_3565507_2 EamA-like transporter family - - - 0.00000000000009586 71.0
PYH3_k127_3613917_0 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715,K07534 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 421.0
PYH3_k127_3613917_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 342.0
PYH3_k127_3613917_2 Protein of unknown function (DUF3429) - - - 0.000000000000000000002371 99.0
PYH3_k127_3613917_3 Zinc-binding dehydrogenase - - - 0.00000000000002105 75.0
PYH3_k127_3685007_0 Belongs to the GcvT family K00315,K19191 - 1.5.3.19,1.5.8.4 0.0 1192.0
PYH3_k127_3685007_1 Elongation factor G, domain IV K02355 - - 2.286e-307 955.0
PYH3_k127_3685007_10 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 306.0
PYH3_k127_3685007_11 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002479 244.0
PYH3_k127_3685007_12 PFAM Thioredoxin domain K03672 - 1.8.1.8 0.00000000000000000000000000000000000000000006812 165.0
PYH3_k127_3685007_13 Putative transposase - - - 0.0000000000000000000000001805 123.0
PYH3_k127_3685007_2 Aldehyde dehydrogenase family - - - 2.626e-212 667.0
PYH3_k127_3685007_3 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003249 599.0
PYH3_k127_3685007_4 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 558.0
PYH3_k127_3685007_5 Protein of unknown function (DUF1298) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 466.0
PYH3_k127_3685007_6 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 449.0
PYH3_k127_3685007_7 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008115 387.0
PYH3_k127_3685007_8 Peptidase C26 K01658,K07010 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 335.0
PYH3_k127_3685007_9 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008078 327.0
PYH3_k127_3690197_0 protein conserved in bacteria K09800 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005921 503.0
PYH3_k127_3690197_1 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009093 426.0
PYH3_k127_3690197_2 surface antigen (D15) K07278 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 426.0
PYH3_k127_369092_0 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008981 412.0
PYH3_k127_369092_1 SMART Prolyl 4-hydroxylase, alpha subunit K00472 - 1.14.11.2 0.0000000000000000000000000000000000000000000136 169.0
PYH3_k127_3691827_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 1.197e-217 686.0
PYH3_k127_3691827_1 IS66 C-terminal element - - - 0.00000000000002613 81.0
PYH3_k127_3691918_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 370.0
PYH3_k127_3691918_1 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004544 322.0
PYH3_k127_3691918_2 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 298.0
PYH3_k127_3691918_3 Transcriptional regulatory protein, C terminal K07659 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002486 286.0
PYH3_k127_3691918_4 Major Facilitator Superfamily - - - 0.0000000000000000000000002603 115.0
PYH3_k127_3691918_5 Belongs to the 'phage' integrase family - - - 0.0000000001189 66.0
PYH3_k127_3704389_0 Alpha amylase, catalytic domain - - - 1.639e-248 778.0
PYH3_k127_3704389_1 Glycogen debranching enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 431.0
PYH3_k127_3704389_2 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 351.0
PYH3_k127_3704389_3 - - - - 0.000000000000000000000000000000000000000000000000000005311 193.0
PYH3_k127_3704389_4 - - - - 0.00000000000000000000000002253 109.0
PYH3_k127_3706829_0 Multicopper oxidase - - - 6.999e-246 777.0
PYH3_k127_3706829_1 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 1.328e-240 751.0
PYH3_k127_3706829_10 Transmembrane exosortase (Exosortase_EpsH) - - - 0.0000000000000000000000000000000000000000000000000000000000005142 222.0
PYH3_k127_3706829_11 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000007372 212.0
PYH3_k127_3706829_12 Diguanylate cyclase, GGDEF domain - - - 0.00000000000000000000000000000000000000000002874 178.0
PYH3_k127_3706829_13 - - - - 0.000000000000000000000000000000000000000003975 164.0
PYH3_k127_3706829_14 - - - - 0.000000000000000000000000001772 119.0
PYH3_k127_3706829_15 - - - - 0.00000000000000000000000742 106.0
PYH3_k127_3706829_16 Domain of unknown function (DUF1840) - - - 0.00000000000000041 82.0
PYH3_k127_3706829_17 Beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000006068 75.0
PYH3_k127_3706829_18 - - - - 0.0000000001178 68.0
PYH3_k127_3706829_2 Prolyl oligopeptidase family - - - 1.758e-229 730.0
PYH3_k127_3706829_3 Sulfatase - - - 1.983e-218 691.0
PYH3_k127_3706829_4 von Willebrand factor, type A K07114 - - 1.849e-204 656.0
PYH3_k127_3706829_5 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 599.0
PYH3_k127_3706829_6 PFAM ATP-binding region, ATPase domain protein K07641 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 465.0
PYH3_k127_3706829_7 Two component transcriptional regulator K07663 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 288.0
PYH3_k127_3706829_8 MOSC domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000003997 238.0
PYH3_k127_3706829_9 PFAM glycosyl transferase, family 51 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001111 248.0
PYH3_k127_3727596_0 Recombinase - - - 0.0 1012.0
PYH3_k127_3727596_1 PFAM RNA-directed DNA polymerase (Reverse transcriptase) K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004721 488.0
PYH3_k127_3727596_2 DNA polymerase K00986 - 2.7.7.49 0.0000000000000001502 85.0
PYH3_k127_3749929_0 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007129 520.0
PYH3_k127_3749929_1 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 332.0
PYH3_k127_3749929_12 PEP-CTERM motif - - - 0.0001506 51.0
PYH3_k127_3749929_2 Cytochrome C oxidase, cbb3-type, subunit III K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 328.0
PYH3_k127_3749929_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.0000000000000000000000000000000000002113 151.0
PYH3_k127_3749929_4 NHL repeat - - - 0.000000000000000000000000000000000006029 140.0
PYH3_k127_3749929_5 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000000000000004128 138.0
PYH3_k127_3749929_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000002545 113.0
PYH3_k127_3749929_7 IS66 Orf2 like protein - - - 0.000000000003405 71.0
PYH3_k127_3749929_8 nuclease K01174 - 3.1.31.1 0.00000000599 60.0
PYH3_k127_3749929_9 - - - - 0.00000009391 60.0
PYH3_k127_3751607_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 1.698e-246 773.0
PYH3_k127_3751607_1 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 4.054e-218 693.0
PYH3_k127_3751607_10 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004583 247.0
PYH3_k127_3751607_11 COG2185 Methylmalonyl-CoA mutase, C-terminal domain subunit (cobalamin-binding) K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000000000000001275 239.0
PYH3_k127_3751607_12 tellurite resistance protein - - - 0.00000000000000000000000000000000000000000000000596 181.0
PYH3_k127_3751607_13 beta-lactamase - - - 0.00000000000000000000000000000000000000002948 157.0
PYH3_k127_3751607_2 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 408.0
PYH3_k127_3751607_3 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008072 349.0
PYH3_k127_3751607_4 phosphoesterase, PHP K07053 GO:0003674,GO:0003824,GO:0005488,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0030145,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0046872,GO:0046914,GO:0097657 3.1.3.97 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 336.0
PYH3_k127_3751607_5 (Lipo)protein K07287 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007147 334.0
PYH3_k127_3751607_6 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003682 313.0
PYH3_k127_3751607_7 Protein of unknown function (DUF455) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 304.0
PYH3_k127_3751607_8 Belongs to the SUA5 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002296 300.0
PYH3_k127_3751607_9 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002592 289.0
PYH3_k127_3759676_0 ABC transporter, ATP-binding protein K18893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 473.0
PYH3_k127_3759676_1 Luciferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003199 472.0
PYH3_k127_3759676_10 Putative transposase - - - 0.000000000005278 79.0
PYH3_k127_3759676_11 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases K00480 - 1.14.13.1 0.00000001195 59.0
PYH3_k127_3759676_12 FAD binding domain K00480 - 1.14.13.1 0.00002068 48.0
PYH3_k127_3759676_2 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005187 468.0
PYH3_k127_3759676_3 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 309.0
PYH3_k127_3759676_4 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000169 217.0
PYH3_k127_3759676_5 Belongs to the peptidase S11 family K07262 - - 0.0000000000000000000000000000000000000000000000000000008593 204.0
PYH3_k127_3759676_6 protein kinase activity - - - 0.000000000000000000000000000000000000000000000000001011 203.0
PYH3_k127_3759676_7 chain release factor K15034 - - 0.00000000000000000000000000000000000000000000000002328 182.0
PYH3_k127_3759676_8 nucleic-acid-binding protein, contains PIN domain - - - 0.000000000000000000000000006683 117.0
PYH3_k127_3759676_9 SpoVT / AbrB like domain - - - 0.00000000000001464 76.0
PYH3_k127_3763641_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002602 302.0
PYH3_k127_3763641_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003867 260.0
PYH3_k127_3763641_2 Cytochrome c - - - 0.0000000000000000000000000000000004258 144.0
PYH3_k127_3763641_3 Menaquinol oxidoreductase complex Cbc4, cytochrome c subunit - - - 0.00000000000000009829 92.0
PYH3_k127_3766512_0 Saccharopine dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002065 397.0
PYH3_k127_3770325_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 GO:0000050,GO:0000053,GO:0003674,GO:0003824,GO:0004055,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006575,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:0072350,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.4.5 8.356e-253 786.0
PYH3_k127_3770325_1 (belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 388.0
PYH3_k127_3770325_10 Response regulator containing a CheY-like receiver domain and a GGDEF domain - - - 0.00000000000000000000001209 116.0
PYH3_k127_3770325_11 Transcriptional regulator, CadC - - - 0.0000000000000000003046 90.0
PYH3_k127_3770325_2 Cell wall formation K00075 - 1.3.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 369.0
PYH3_k127_3770325_3 TIR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004157 334.0
PYH3_k127_3770325_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 327.0
PYH3_k127_3770325_5 Belongs to the UPF0234 family K09767 - - 0.000000000000000000000000000000000000000000000000000000000004883 213.0
PYH3_k127_3770325_6 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000004708 166.0
PYH3_k127_3770325_7 PFAM Uncharacterised protein family UPF0150 - - - 0.000000000000000000000000009349 110.0
PYH3_k127_3770325_8 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 GO:0000050,GO:0003674,GO:0003824,GO:0004585,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006591,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016740,GO:0016741,GO:0016743,GO:0019627,GO:0019752,GO:0034641,GO:0042450,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.1.3.3 0.00000000000000000000000001124 109.0
PYH3_k127_3770325_9 mRNA binding - - - 0.00000000000000000000000002583 115.0
PYH3_k127_3783798_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 9.433e-315 979.0
PYH3_k127_3783798_1 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 2.693e-224 700.0
PYH3_k127_3783798_10 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000002257 129.0
PYH3_k127_3783798_11 Trm112p-like protein K09791 - - 0.00000000000000000000006548 99.0
PYH3_k127_3783798_2 ABC-type dipeptide transport system, periplasmic component K02035 - - 1.104e-212 672.0
PYH3_k127_3783798_3 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004344 347.0
PYH3_k127_3783798_4 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 317.0
PYH3_k127_3783798_5 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 305.0
PYH3_k127_3783798_6 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000001932 223.0
PYH3_k127_3783798_7 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.00000000000000000000000000000000000000000000000000000000000917 212.0
PYH3_k127_3783798_8 COG1335 Amidases related to nicotinamidase - - - 0.000000000000000000000000000000000000000000003188 169.0
PYH3_k127_3783798_9 Biopolymer transport protein ExbD TolR K03559 - - 0.0000000000000000000000000000000000016 147.0
PYH3_k127_3792756_0 methionine synthase K00544,K00548 - 2.1.1.13,2.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004167 490.0
PYH3_k127_3792756_1 abc transporter atp-binding protein K05847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 399.0
PYH3_k127_3792756_2 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004628 304.0
PYH3_k127_3792756_3 Binding-protein-dependent transport system inner membrane component K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004858 292.0
PYH3_k127_3792756_4 Glycine betaine ABC transporter substrate-binding protein K05845 - - 0.00000000000000000000000000000000000000000005098 164.0
PYH3_k127_3792756_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000003252 98.0
PYH3_k127_379708_0 Two component, sigma54 specific, transcriptional regulator, Fis family K02481,K07714 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 576.0
PYH3_k127_379708_1 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 409.0
PYH3_k127_379708_2 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000000000000000000000000009339 239.0
PYH3_k127_379708_3 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.00000000000000000000000000000000000000000000000001624 189.0
PYH3_k127_3805784_0 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0 1007.0
PYH3_k127_3805784_1 NMT1-like family K07080 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001866 520.0
PYH3_k127_3805784_2 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.000000000000000000000000000000000000001689 153.0
PYH3_k127_3805784_3 protein related to plant photosystem II stability assembly factor - - - 0.00001942 54.0
PYH3_k127_3832983_0 Protein of unknown function - - - 3.89e-274 891.0
PYH3_k127_3832983_1 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 3.586e-267 854.0
PYH3_k127_3832983_10 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006228 319.0
PYH3_k127_3832983_11 Bacterial protein of unknown function (DUF937) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004212 271.0
PYH3_k127_3832983_12 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000006403 239.0
PYH3_k127_3832983_13 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001347 213.0
PYH3_k127_3832983_14 branched-chain amino acid permease (azaleucine resistance) - - - 0.00000000000000000000000000000000000000000000000000000002292 206.0
PYH3_k127_3832983_15 Domain of unknown function (DUF3597) - - - 0.00000000000000000000000000000000000000000000000000001154 194.0
PYH3_k127_3832983_16 SnoaL-like domain - - - 0.0000000000000000000000000000001423 129.0
PYH3_k127_3832983_17 TIR domain - - - 0.000000000000000000000000001777 129.0
PYH3_k127_3832983_18 Zinc-finger domain - - - 0.000000000000000000000001159 106.0
PYH3_k127_3832983_19 Branched-chain amino acid transport protein (AzlD) - - - 0.00000000000000000009149 101.0
PYH3_k127_3832983_2 peptidase U62, modulator of DNA gyrase K03568 - - 4.889e-213 674.0
PYH3_k127_3832983_20 Major facilitator superfamily - - - 0.0000007529 52.0
PYH3_k127_3832983_3 MFS/sugar transport protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 587.0
PYH3_k127_3832983_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003022 497.0
PYH3_k127_3832983_5 mechanosensitive ion channel K03442,K16052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005987 419.0
PYH3_k127_3832983_6 alpha/beta hydrolase fold K07019 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 399.0
PYH3_k127_3832983_7 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008046 378.0
PYH3_k127_3832983_8 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008146 372.0
PYH3_k127_3832983_9 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 319.0
PYH3_k127_3840283_0 Domain of unknown function (DUF3362) - - - 0.0 1237.0
PYH3_k127_3840283_1 X-Pro dipeptidyl-peptidase (S15 family) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 461.0
PYH3_k127_3840283_10 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000002775 250.0
PYH3_k127_3840283_11 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K04756 - - 0.0000000000000000000000000000000000000000000000000000000000000000000026 240.0
PYH3_k127_3840283_12 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000005745 231.0
PYH3_k127_3840283_13 Ion transport 2 domain protein K10716 - - 0.000000000000000000000000000000000000000000000000000000000001621 218.0
PYH3_k127_3840283_14 TspO/MBR family K05770 - - 0.000000000000000000000000000000000000000000000000000000000005197 214.0
PYH3_k127_3840283_15 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000001806 207.0
PYH3_k127_3840283_16 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.0000000000000000000000000000000000000000000000000000002504 210.0
PYH3_k127_3840283_17 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000000000000000007369 198.0
PYH3_k127_3840283_18 TPM domain - - - 0.00000000000000000000000000000000000000000000000005305 184.0
PYH3_k127_3840283_19 - - - - 0.0000000000000000000000000000000000001492 145.0
PYH3_k127_3840283_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001977 402.0
PYH3_k127_3840283_20 SnoaL-like domain - - - 0.000000000000000000000000000000000747 134.0
PYH3_k127_3840283_21 Protein of unknown function (DUF2892) - - - 0.00000000000000000000001383 102.0
PYH3_k127_3840283_22 UBA THIF-type NAD FAD binding K22132 - - 0.00000000000000003649 82.0
PYH3_k127_3840283_3 Protein of unknown function DUF72 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 357.0
PYH3_k127_3840283_4 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 329.0
PYH3_k127_3840283_5 Tellurite resistance protein TerB - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002923 330.0
PYH3_k127_3840283_6 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 327.0
PYH3_k127_3840283_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004184 289.0
PYH3_k127_3840283_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002112 288.0
PYH3_k127_3840283_9 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004041 290.0
PYH3_k127_3848668_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000008548 177.0
PYH3_k127_3848668_1 exo-alpha-(2->6)-sialidase activity - - - 0.00000000000000000000000000000008026 143.0
PYH3_k127_3848668_2 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00008505 48.0
PYH3_k127_3856924_0 Sulfate permease and related transporters (MFS superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000004457 253.0
PYH3_k127_3856924_1 membrane - - - 0.000000000000000000000000000000000000000000000000000000000001055 219.0
PYH3_k127_3856924_2 - - - - 0.00000000000000000000000000000000000000000000000000000000004713 216.0
PYH3_k127_3856924_3 Gram-negative porin - GO:0005575,GO:0005623,GO:0009279,GO:0016020,GO:0019867,GO:0030312,GO:0030313,GO:0031975,GO:0044462,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000005006 204.0
PYH3_k127_3873706_0 NADPH quinone reductase and related Zn-dependent oxidoreductases K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002294 484.0
PYH3_k127_3873706_1 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 308.0
PYH3_k127_3873706_2 of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000007996 142.0
PYH3_k127_3876913_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 2.66e-240 766.0
PYH3_k127_3876913_1 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000009525 222.0
PYH3_k127_3876913_2 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 0.000000000000000000000000000000000002938 141.0
PYH3_k127_3880783_0 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 9.284e-238 750.0
PYH3_k127_3880783_1 Type II secretory pathway, component ExeA K02450 - - 3.837e-198 634.0
PYH3_k127_3880783_10 B12 binding domain K01849 GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016853,GO:0016866,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0036094,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046906,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:1901135,GO:1901360,GO:1901363,GO:1901564 5.4.99.2 0.000000000000000000000000000000000000000000004776 175.0
PYH3_k127_3880783_11 Type II secretion system protein B K02451 - - 0.0000000000000000000000000000000000000000001396 168.0
PYH3_k127_3880783_12 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000222 130.0
PYH3_k127_3880783_13 GYD domain - - - 0.0000000000000000000000000001378 117.0
PYH3_k127_3880783_14 LCCL domain - - - 0.00000000000005621 78.0
PYH3_k127_3880783_15 SnoaL-like domain - - - 0.000000002643 63.0
PYH3_k127_3880783_2 D-isomer specific 2-hydroxyacid dehydrogenase catalytic K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 459.0
PYH3_k127_3880783_3 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 428.0
PYH3_k127_3880783_4 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007321 382.0
PYH3_k127_3880783_5 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 330.0
PYH3_k127_3880783_6 Putative metallopeptidase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 309.0
PYH3_k127_3880783_7 Endonuclease Exonuclease Phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 289.0
PYH3_k127_3880783_8 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000000006771 211.0
PYH3_k127_3880783_9 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000006685 179.0
PYH3_k127_3911129_0 FAD linked oxidase domain protein - - - 3.109e-215 678.0
PYH3_k127_3911129_1 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 3.346e-213 668.0
PYH3_k127_3911129_10 lipase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000007515 234.0
PYH3_k127_3911129_11 COG3090 TRAP-type C4-dicarboxylate transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000002506 190.0
PYH3_k127_3911129_12 PQ loop repeat K15383 - - 0.00000000000000000000184 94.0
PYH3_k127_3911129_2 Aminotransferase K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 5.923e-207 650.0
PYH3_k127_3911129_3 PFAM L-carnitine dehydratase bile acid-inducible protein F K07749 - 2.8.3.16 4.415e-204 640.0
PYH3_k127_3911129_4 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 486.0
PYH3_k127_3911129_5 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009214 452.0
PYH3_k127_3911129_6 enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 407.0
PYH3_k127_3911129_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005601 328.0
PYH3_k127_3911129_8 Regulatory protein GntR HTH - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000225 274.0
PYH3_k127_3911129_9 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000002442 245.0
PYH3_k127_3926314_0 Ketopantoate hydroxymethyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004278 496.0
PYH3_k127_3926314_1 Phytanoyl-CoA dioxygenase (PhyH) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003436 377.0
PYH3_k127_3926314_2 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 353.0
PYH3_k127_3926314_3 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001118 266.0
PYH3_k127_3926314_4 Uroporphyrinogen decarboxylase (URO-D) - - - 0.00000000000000000000000000000000000000000000000000000000000000009906 240.0
PYH3_k127_3926314_5 COG1145 Ferredoxin - - - 0.000000000000000000000000000000000000000000000000000000000007495 216.0
PYH3_k127_3926314_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - GO:0003674,GO:0005488,GO:0005509,GO:0005515,GO:0005575,GO:0005623,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008270,GO:0015711,GO:0015718,GO:0015727,GO:0015849,GO:0015850,GO:0031317,GO:0032991,GO:0042802,GO:0042803,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0046942,GO:0046983,GO:0051179,GO:0051234,GO:0071702,GO:1990351 - 0.0000000000000000000000000000000000000000000001964 177.0
PYH3_k127_3931895_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 0.0 1559.0
PYH3_k127_3931895_1 cysteine protease - - - 2.911e-232 738.0
PYH3_k127_3931895_10 Belongs to the short-chain dehydrogenases reductases (SDR) family K00019 GO:0000003,GO:0000166,GO:0001568,GO:0001676,GO:0001944,GO:0003674,GO:0003824,GO:0004888,GO:0004930,GO:0004953,GO:0004954,GO:0004955,GO:0004957,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006636,GO:0006690,GO:0006692,GO:0006693,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007179,GO:0007186,GO:0007275,GO:0007276,GO:0007292,GO:0007565,GO:0007567,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009653,GO:0009719,GO:0009987,GO:0010033,GO:0016053,GO:0016404,GO:0016491,GO:0016614,GO:0016616,GO:0019372,GO:0019752,GO:0019953,GO:0022414,GO:0023052,GO:0030728,GO:0031974,GO:0031981,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0033559,GO:0035239,GO:0035295,GO:0036094,GO:0038023,GO:0042221,GO:0042759,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0045786,GO:0046394,GO:0046456,GO:0046983,GO:0048037,GO:0048514,GO:0048519,GO:0048523,GO:0048609,GO:0048731,GO:0048844,GO:0048856,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051287,GO:0051704,GO:0051716,GO:0051726,GO:0055114,GO:0060089,GO:0060840,GO:0065007,GO:0070013,GO:0070403,GO:0070493,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071559,GO:0071560,GO:0071704,GO:0072330,GO:0072358,GO:0072359,GO:0097070,GO:0097159,GO:1901265,GO:1901363,GO:1901568,GO:1901570,GO:1901576,GO:2001300,GO:2001301 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001402 448.0
PYH3_k127_3931895_11 Phosphoenolpyruvate phosphomutase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007253 426.0
PYH3_k127_3931895_12 Patatin phospholipase K07001 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007181 412.0
PYH3_k127_3931895_13 Catalyzes the conversion of acetoacetate to acetone and carbon dioxide - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000344 396.0
PYH3_k127_3931895_14 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007194 329.0
PYH3_k127_3931895_15 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003194 270.0
PYH3_k127_3931895_16 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000005958 258.0
PYH3_k127_3931895_17 Alpha/beta hydrolase family K06889 - - 0.000000000000000000000000000000000000000000000000000000000545 213.0
PYH3_k127_3931895_18 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000000000000000000000000000000000000004873 204.0
PYH3_k127_3931895_19 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000002103 199.0
PYH3_k127_3931895_2 L-serine dehydratase K01752 - 4.3.1.17 1.855e-228 719.0
PYH3_k127_3931895_20 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.000000000000000000000000000000000000000000000000002432 184.0
PYH3_k127_3931895_21 peptidyl-tyrosine sulfation - - - 0.000000000000000000000003609 112.0
PYH3_k127_3931895_22 abc transporter K06020 - 3.6.3.25 0.000000000000000008964 86.0
PYH3_k127_3931895_23 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.00000000009476 73.0
PYH3_k127_3931895_3 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 591.0
PYH3_k127_3931895_4 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 586.0
PYH3_k127_3931895_5 Belongs to the amidase family K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 562.0
PYH3_k127_3931895_6 Phosphate transporter family K03306 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002335 533.0
PYH3_k127_3931895_7 Citrate transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005505 520.0
PYH3_k127_3931895_8 D-aminoacylase domain protein K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 519.0
PYH3_k127_3931895_9 The glycine cleavage system catalyzes the degradation of glycine K00605 - 2.1.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001278 458.0
PYH3_k127_3949224_0 Ammonium transporter K03320 - - 3.404e-230 726.0
PYH3_k127_3949224_1 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.099e-208 656.0
PYH3_k127_3949224_10 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003242 471.0
PYH3_k127_3949224_11 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 403.0
PYH3_k127_3949224_12 Flavin containing amine oxidoreductase K00231,K14266 - 1.14.19.9,1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004538 375.0
PYH3_k127_3949224_13 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 355.0
PYH3_k127_3949224_14 haloacid dehalogenase-like hydrolase K02203 - 2.7.1.39,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001935 348.0
PYH3_k127_3949224_15 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 326.0
PYH3_k127_3949224_16 Domain of unknown function (DUF4382) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 312.0
PYH3_k127_3949224_17 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004275 271.0
PYH3_k127_3949224_18 Phosphoribosyl transferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 266.0
PYH3_k127_3949224_19 Methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000249 261.0
PYH3_k127_3949224_2 Glutamate-cysteine ligase K01919 - 6.3.2.2 7.947e-199 629.0
PYH3_k127_3949224_20 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002369 257.0
PYH3_k127_3949224_21 Peptidase M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000003659 244.0
PYH3_k127_3949224_22 Bacterial protein of unknown function (Gcw_chp) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003228 237.0
PYH3_k127_3949224_23 Alpha/beta hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000007422 236.0
PYH3_k127_3949224_24 Belongs to the P(II) protein family K04752 - - 0.000000000000000000000000000000000000000000000000000000000002419 212.0
PYH3_k127_3949224_25 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000001821 204.0
PYH3_k127_3949224_26 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000291 198.0
PYH3_k127_3949224_27 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000368 188.0
PYH3_k127_3949224_28 pts system fructose subfamily IIa component K02821 - 2.7.1.194 0.000000000000000000000000000000000000007525 152.0
PYH3_k127_3949224_29 Magnesium chelatase, subunit ChlI K07391 - - 0.00000000000000000000000000007115 117.0
PYH3_k127_3949224_3 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 1.868e-194 613.0
PYH3_k127_3949224_30 - - - - 0.0000000000000000000000000002662 123.0
PYH3_k127_3949224_31 PTS HPr component phosphorylation site K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000000000000001378 114.0
PYH3_k127_3949224_32 Membrane fusogenic activity K09806 - - 0.0000000000000000001933 90.0
PYH3_k127_3949224_33 cytochrome complex assembly - - - 0.00000000001154 75.0
PYH3_k127_3949224_4 4Fe-4S single cluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 587.0
PYH3_k127_3949224_5 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 605.0
PYH3_k127_3949224_6 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K03385 GO:0003674,GO:0003824,GO:0005488,GO:0005509,GO:0005575,GO:0005623,GO:0006807,GO:0008150,GO:0008152,GO:0016491,GO:0016661,GO:0016662,GO:0020037,GO:0042279,GO:0042597,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046906,GO:0048037,GO:0055114,GO:0097159,GO:0097164,GO:0098809,GO:1901363 1.7.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004786 586.0
PYH3_k127_3949224_7 Major facilitator superfamily K08218 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006764 574.0
PYH3_k127_3949224_8 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 548.0
PYH3_k127_3949224_9 L-lysine 6-monooxygenase (NADPH-requiring) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003282 493.0
PYH3_k127_3961126_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0 1203.0
PYH3_k127_3961126_1 PUA-like domain K00958 - 2.7.7.4 1.865e-213 669.0
PYH3_k127_3961126_2 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004987 368.0
PYH3_k127_3961126_3 reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 314.0
PYH3_k127_3961126_4 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000004858 230.0
PYH3_k127_3961126_5 - - - - 0.000000000001358 70.0
PYH3_k127_3967470_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.32e-251 783.0
PYH3_k127_3967470_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 GO:0000162,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0042802,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.20 2.104e-227 708.0
PYH3_k127_3967470_10 LysM domain K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 319.0
PYH3_k127_3967470_11 Belongs to the TrpF family K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000005875 215.0
PYH3_k127_3967470_12 Sporulation related domain K03749 - - 0.0000000000000000000000124 110.0
PYH3_k127_3967470_13 Putative lumazine-binding - - - 0.0000000000000000000003462 104.0
PYH3_k127_3967470_14 Colicin V production protein K03558 - - 0.000000000000000000002029 102.0
PYH3_k127_3967470_15 Helix-hairpin-helix motif - - - 0.000000000000000000005388 96.0
PYH3_k127_3967470_16 4 iron, 4 sulfur cluster binding K00176,K00528,K03737,K20449 - 1.18.1.2,1.19.1.1,1.2.7.1,1.2.7.3,1.3.7.1 0.00000000000000000146 89.0
PYH3_k127_3967470_17 - - - - 0.0000000000000008731 88.0
PYH3_k127_3967470_19 Domain of unknown function (DUF932) - - - 0.000134 44.0
PYH3_k127_3967470_2 Retron-type reverse transcriptase K00986 - 2.7.7.49 1.5e-204 653.0
PYH3_k127_3967470_3 Epoxide hydrolase N terminus K01253 - 3.3.2.9 4.849e-196 619.0
PYH3_k127_3967470_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 571.0
PYH3_k127_3967470_5 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K10764 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001183 512.0
PYH3_k127_3967470_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002226 488.0
PYH3_k127_3967470_7 Lipoprotein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 373.0
PYH3_k127_3967470_8 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 367.0
PYH3_k127_3967470_9 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 319.0
PYH3_k127_39685_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.0 1148.0
PYH3_k127_39685_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 1e-323 994.0
PYH3_k127_398894_0 Evidence 2b Function of strongly homologous gene - - - 7.244e-253 788.0
PYH3_k127_398894_1 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002163 446.0
PYH3_k127_398894_2 PFAM Integrase catalytic region - - - 0.0000000005256 64.0
PYH3_k127_398894_3 PFAM RNA-directed DNA polymerase (reverse transcriptase) - - - 0.0001211 45.0
PYH3_k127_3991592_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1398.0
PYH3_k127_3991592_1 COG4231 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.0 1380.0
PYH3_k127_3991592_10 Neisseria PilC beta-propeller domain K02674 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 509.0
PYH3_k127_3991592_11 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005843 472.0
PYH3_k127_3991592_12 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006678 425.0
PYH3_k127_3991592_13 Binding-protein-dependent transport system inner membrane component K02054,K11071,K11075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 395.0
PYH3_k127_3991592_14 Required for the activity of the bacterial periplasmic transport system of putrescine K02055,K11069,K11073 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 392.0
PYH3_k127_3991592_15 Binding-protein-dependent transport system inner membrane component K11070,K11074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007083 369.0
PYH3_k127_3991592_16 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000776 369.0
PYH3_k127_3991592_17 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005033 298.0
PYH3_k127_3991592_18 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.0000000000000000000000000000000000000000000000000000000000000000000002211 239.0
PYH3_k127_3991592_19 import inner membrane translocase, subunit Tim44 - - - 0.00000000000000000000000000000000000000000000000000000000001803 218.0
PYH3_k127_3991592_2 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 6.441e-314 969.0
PYH3_k127_3991592_20 PFAM regulatory protein AsnC Lrp family K03719 - - 0.0000000000000000000000000000000000000000000000000000000003101 211.0
PYH3_k127_3991592_21 Protein of unknown function (DUF971) - - - 0.000000000000000000000000000000000000000000000000000009071 192.0
PYH3_k127_3991592_22 Thiopurine S-methyltransferase (TPMT) - - - 0.000000000000000000000000000000000000000000000000005533 188.0
PYH3_k127_3991592_23 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000223 166.0
PYH3_k127_3991592_24 - - - - 0.000000000000000000000000000000003224 140.0
PYH3_k127_3991592_25 PFAM Sterol-binding domain protein K03690 - - 0.000000000000000000000000000000003634 137.0
PYH3_k127_3991592_26 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000685 87.0
PYH3_k127_3991592_27 Pilus assembly protein PilX K02673 - - 0.0000000000000351 79.0
PYH3_k127_3991592_3 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K00074 - 1.1.1.157 3.384e-304 944.0
PYH3_k127_3991592_4 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 6.485e-290 902.0
PYH3_k127_3991592_5 Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis K03688 - - 6.043e-219 697.0
PYH3_k127_3991592_6 CoA-transferase family III - - - 2.583e-210 665.0
PYH3_k127_3991592_7 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 572.0
PYH3_k127_3991592_8 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 498.0
PYH3_k127_3991592_9 branched-chain amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002345 477.0
PYH3_k127_4005644_0 Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate. Also shows phosphatase, 2'- nucleotidase and 2',3'-cyclic phosphodiesterase activities. These phosphohydrolase activities are probably involved in the repair of the tRNA 3'-CCA terminus degraded by intracellular RNases K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002974 570.0
PYH3_k127_4005644_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009389 554.0
PYH3_k127_4005644_2 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 460.0
PYH3_k127_4005644_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003119 379.0
PYH3_k127_4005644_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003611 325.0
PYH3_k127_4005644_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 320.0
PYH3_k127_4005644_6 NAD(P)H-binding K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008291 317.0
PYH3_k127_4005644_7 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000000000000000000005715 175.0
PYH3_k127_4005644_8 EXOIII K02342 - 2.7.7.7 0.000000000000000000000000000000000005773 145.0
PYH3_k127_4005644_9 Protein of unknown function (DUF2905) - - - 0.00000000000000017 80.0
PYH3_k127_4016994_0 Belongs to the ABC transporter superfamily K02052,K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001236 436.0
PYH3_k127_4016994_1 Bacterial extracellular solute-binding protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002279 417.0
PYH3_k127_4016994_2 COG1176 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002578 381.0
PYH3_k127_4016994_3 transcriptional - - - 0.0000000000000000000000000000000000000000001548 170.0
PYH3_k127_4016994_4 Acyl-transferase - - - 0.0000000000000000000000003264 107.0
PYH3_k127_4016994_5 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000001107 98.0
PYH3_k127_4029664_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000361 534.0
PYH3_k127_4029664_1 ATPase family associated with various cellular activities (AAA) - - - 0.0000000000000000000000000000000000005754 156.0
PYH3_k127_4029664_2 - - - - 0.00000000000003941 74.0
PYH3_k127_4029664_3 lipoate-protein ligase A - - - 0.00004567 47.0
PYH3_k127_4036906_0 Glucodextranase, domain N K01178 - 3.2.1.3 2.357e-321 1000.0
PYH3_k127_4036906_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005371 361.0
PYH3_k127_4036906_2 Transposase and inactivated derivatives, IS5 family K07481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000006359 260.0
PYH3_k127_4036906_3 Transposase and inactivated derivatives, IS5 family K07481 - - 0.00000000000005165 74.0
PYH3_k127_408795_0 Penicillin amidase K01434 - 3.5.1.11 5.514e-320 1004.0
PYH3_k127_408795_1 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000007519 67.0
PYH3_k127_4129367_0 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 1.181e-211 660.0
PYH3_k127_4129367_1 4-hydroxybenzoate 3-monooxygenase K00481 - 1.14.13.2 4.695e-201 631.0
PYH3_k127_4129367_2 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 573.0
PYH3_k127_4129367_3 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 539.0
PYH3_k127_4129367_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000805 494.0
PYH3_k127_4129367_5 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000002554 218.0
PYH3_k127_4129367_6 Tripartite ATP-independent periplasmic transporter dctq component - - - 0.0000000000000000000000000000000000000000000000000005938 194.0
PYH3_k127_4131406_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0 1638.0
PYH3_k127_4131406_1 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 442.0
PYH3_k127_4131406_2 Nitrate reductase delta subunit - - - 0.000000000000000000000001878 108.0
PYH3_k127_4134298_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 0.0 1105.0
PYH3_k127_4134298_1 PFAM cell divisionFtsK SpoIIIE K03466 - - 5.353e-302 947.0
PYH3_k127_4134298_10 cation diffusion facilitator family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002417 368.0
PYH3_k127_4134298_11 LytTr DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
PYH3_k127_4134298_12 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.000000000000000000000000000000000000000000000000000000000000000003257 240.0
PYH3_k127_4134298_13 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000000000886 227.0
PYH3_k127_4134298_14 FKBP-type peptidyl-prolyl cis-trans isomerase K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000241 209.0
PYH3_k127_4134298_15 CHRD domain - - - 0.0000000000000000000000000000000000000000000000000000003485 200.0
PYH3_k127_4134298_16 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000003707 194.0
PYH3_k127_4134298_17 - - - - 0.00000000000000000000000000000000000003909 149.0
PYH3_k127_4134298_18 Histidine kinase - - - 0.000000000000000000001141 109.0
PYH3_k127_4134298_19 TIGRFAM glutamine synthetase, type I K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 0.00000000000005905 71.0
PYH3_k127_4134298_2 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 1.475e-216 681.0
PYH3_k127_4134298_21 Antirepressor K07741 - - 0.0009869 49.0
PYH3_k127_4134298_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 3.083e-214 672.0
PYH3_k127_4134298_4 Extracellular solute-binding protein K02055,K11069 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006919 597.0
PYH3_k127_4134298_5 MgsA AAA+ ATPase C terminal K07478 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 594.0
PYH3_k127_4134298_6 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 483.0
PYH3_k127_4134298_7 Binding-protein-dependent transport system inner membrane component K11071 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002313 451.0
PYH3_k127_4134298_8 Binding-protein-dependent transport system inner membrane component K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 417.0
PYH3_k127_4134298_9 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 401.0
PYH3_k127_4181075_0 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 526.0
PYH3_k127_4181075_1 Integrase core domain K07497 - - 0.0000004005 51.0
PYH3_k127_4278432_0 Prolyl oligopeptidase K01322 - 3.4.21.26 2.01e-225 717.0
PYH3_k127_4278432_1 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 419.0
PYH3_k127_4278432_2 Sulfite exporter TauE/SafE K07090 - - 0.000000000000000000000000000000000000000000000000000000000000001137 226.0
PYH3_k127_4278432_3 - - - - 0.000000000000000000000000000000002206 136.0
PYH3_k127_4339325_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 9.884e-247 776.0
PYH3_k127_4339325_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003985 534.0
PYH3_k127_4339325_10 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.000000000000000000000000000000000000000002909 160.0
PYH3_k127_4339325_11 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000001691 159.0
PYH3_k127_4339325_12 Domain of unknown function (DUF4845) - - - 0.00000000000000000000429 97.0
PYH3_k127_4339325_14 - - - - 0.000006097 50.0
PYH3_k127_4339325_2 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 395.0
PYH3_k127_4339325_3 Plays a role in peptidoglycan recycling by cleaving the terminal beta-1,4-linked N-acetylglucosamine (GlcNAc) from peptide-linked peptidoglycan fragments, giving rise to free GlcNAc, anhydro-N-acetylmuramic acid and anhydro-N-acetylmuramic acid-linked peptides K00997,K01207 - 2.7.8.7,3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004653 391.0
PYH3_k127_4339325_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 354.0
PYH3_k127_4339325_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
PYH3_k127_4339325_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006783 323.0
PYH3_k127_4339325_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002273 278.0
PYH3_k127_4339325_8 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.000000000000000000000000000000000000000000000000000000000000000000000001377 254.0
PYH3_k127_4339325_9 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000005219 194.0
PYH3_k127_4358014_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2113.0
PYH3_k127_4358014_1 XFP C-terminal domain K01621 - 4.1.2.22,4.1.2.9 0.0 1358.0
PYH3_k127_4358014_2 Carbohydrate phosphorylase K00688,K16153 - 2.4.1.1,2.4.1.11 1.042e-215 683.0
PYH3_k127_4358014_3 Magnesium transport protein CorA - - - 7.589e-205 661.0
PYH3_k127_4358014_4 Belongs to the arylamine N-acetyltransferase family K00675 - 2.3.1.118 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001158 355.0
PYH3_k127_4358014_5 Glutathione-dependent formaldehyde-activating - - - 0.00000000000000000000000000000000000000000000000000000004232 198.0
PYH3_k127_4379932_0 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 509.0
PYH3_k127_4379932_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006043 387.0
PYH3_k127_4379932_10 Histidine kinase - - - 0.00000002245 57.0
PYH3_k127_4379932_11 Histidine kinase - - - 0.00008456 46.0
PYH3_k127_4379932_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K21563 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002493 259.0
PYH3_k127_4379932_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000009095 187.0
PYH3_k127_4379932_4 - - - - 0.0000000000000000000000000000000000000000001496 168.0
PYH3_k127_4379932_5 Histidine kinase - - - 0.00000000000000000000000000004621 122.0
PYH3_k127_4379932_6 receptor K16087 - - 0.0000000000000000000009599 100.0
PYH3_k127_4379932_7 Cytochrome oxidase assembly protein K02259 - - 0.000000000000000000004417 109.0
PYH3_k127_4379932_8 redox protein, regulator of disulfide bond formation - - - 0.0000000000003389 81.0
PYH3_k127_4379932_9 Histidine kinase - - - 0.0000000214 55.0
PYH3_k127_4417025_0 PFAM Transposase, IS801 IS1294 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 467.0
PYH3_k127_4417025_1 Belongs to the 'phage' integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003703 318.0
PYH3_k127_4417025_2 Bacterial pullanase-associated domain - - - 0.0003703 43.0
PYH3_k127_4444714_0 Amidase, hydantoinase carbamoylase family K02083,K06016 - 3.5.1.6,3.5.1.87,3.5.3.9 3.56e-322 992.0
PYH3_k127_4444714_1 peptidase dimerisation domain protein - - - 2.892e-207 651.0
PYH3_k127_4444714_2 deacetylase K01452 - 3.5.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007415 588.0
PYH3_k127_4444714_3 Xanthine dehydrogenase small subunit K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 533.0
PYH3_k127_4444714_4 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 308.0
PYH3_k127_4444714_5 Nucleoside-binding outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000005108 221.0
PYH3_k127_4444714_6 Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily K07127 - 3.5.2.17 0.0000000000000000000000000000000000000000000000000004078 186.0
PYH3_k127_4444714_7 FCD - - - 0.0000000000000000000000000000000000000000000000006677 184.0
PYH3_k127_4444714_8 Domain of unknown function (DUF4124) - - - 0.000002829 55.0
PYH3_k127_4444714_9 PFAM sodium hydrogen exchanger K03316 - - 0.0006363 46.0
PYH3_k127_445669_0 FAD binding domain K00394 - 1.8.99.2 3.209e-201 629.0
PYH3_k127_445669_1 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003759 562.0
PYH3_k127_445669_2 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 365.0
PYH3_k127_445669_4 - - - - 0.00000000000000000000004361 104.0
PYH3_k127_445669_5 - - - - 0.00000009651 59.0
PYH3_k127_4511088_0 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 556.0
PYH3_k127_4511088_1 permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 477.0
PYH3_k127_4511088_2 membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009696 324.0
PYH3_k127_4511088_3 crp fnr family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000304 281.0
PYH3_k127_4511088_4 Ferritin, Dps family protein K03594 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004369 275.0
PYH3_k127_4511088_5 PFAM transport-associated K04065 - - 0.000000000000000000000000000000000001988 139.0
PYH3_k127_4511088_6 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000001495 136.0
PYH3_k127_4511088_7 PFAM transport-associated K04065 - - 0.00000000000000000000000000007992 119.0
PYH3_k127_4511088_8 Protein of unknown function (DUF3096) - - - 0.00000000000002944 73.0
PYH3_k127_4576352_0 Signal transduction histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 409.0
PYH3_k127_4576352_1 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07657 - - 0.0000000000000000000000000000000000000000000000000000000000002911 215.0
PYH3_k127_4578714_0 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000000000001076 155.0
PYH3_k127_4578714_1 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000006104 146.0
PYH3_k127_4578714_2 PIN domain - - - 0.000000000000000000000000000002914 120.0
PYH3_k127_4578714_3 SpoVT / AbrB like domain K07172 - - 0.00000000000000000000000001046 115.0
PYH3_k127_4623660_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 2.855e-279 878.0
PYH3_k127_4623660_1 protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 406.0
PYH3_k127_4623660_2 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS - - - 0.000000000000000000000000000000000000000000000000000000002344 207.0
PYH3_k127_4623660_3 Domain of unknown function (DUF4396) - - - 0.00000000000000000000000000000000000000000000000000003118 195.0
PYH3_k127_4623660_4 helix_turn_helix, mercury resistance K19591 - - 0.00000000000000000000000000000000000000000000000000003349 192.0
PYH3_k127_4623660_5 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000001843 152.0
PYH3_k127_4623660_7 - - - - 0.0000000000000000000000000000461 117.0
PYH3_k127_4623701_0 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001326 410.0
PYH3_k127_4623701_1 Insertion element 4 transposase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006061 404.0
PYH3_k127_4623701_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000001993 195.0
PYH3_k127_4623701_3 coenzyme F420 binding K07226 - - 0.000000000000000000000000000000000000000009893 159.0
PYH3_k127_4623701_5 - - - - 0.0000000000000000000000000000461 117.0
PYH3_k127_4691942_0 Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits K04090 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001142 587.0
PYH3_k127_4691942_1 membrane - - - 0.000000000000000000000000000000000000000000000000000232 189.0
PYH3_k127_4691942_2 aminotransferase class I and II - - - 0.0000000000009871 68.0
PYH3_k127_4709777_0 PFAM major facilitator superfamily MFS_1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009243 508.0
PYH3_k127_4709777_1 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005043 488.0
PYH3_k127_4709777_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001299 266.0
PYH3_k127_4709777_3 Domain of unknown function (DUF4440) - - - 0.0000000000000000000000000000000000000000000000008434 182.0
PYH3_k127_4709777_4 PepSY-associated TM region - - - 0.000000000000000000000000000000000000000000004263 179.0
PYH3_k127_485353_0 Glucose / Sorbosone dehydrogenase - - - 5.884e-245 758.0
PYH3_k127_485353_1 TonB-dependent receptor K02014 - - 0.00000000000000000000000000000002829 128.0
PYH3_k127_485353_2 PFAM Cytochrome C K17230 - - 0.000000000000000000000000001919 115.0
PYH3_k127_4882335_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00370,K17050 - 1.7.5.1 0.0 2100.0
PYH3_k127_4882335_1 nitrite transporter K02575 - - 7.855e-307 946.0
PYH3_k127_4882335_2 Major Facilitator Superfamily K02575 - - 7.357e-211 660.0
PYH3_k127_4882335_3 Nitrate reductase beta subunit K00371,K17051 - 1.7.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 482.0
PYH3_k127_4911206_0 Belongs to the TPP enzyme family K03852 - 2.3.3.15 2.326e-256 798.0
PYH3_k127_4911206_1 Transcriptional regulator - - - 0.0000000006385 63.0
PYH3_k127_4913285_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002961 566.0
PYH3_k127_4913285_1 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 472.0
PYH3_k127_4913285_2 UTP--glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 350.0
PYH3_k127_4913285_3 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000006722 249.0
PYH3_k127_4913285_4 Belongs to the GPI family K01810 - 5.3.1.9 0.00000000000000000000000000000000002225 139.0
PYH3_k127_4914545_0 Dehydrogenase E1 component K00164 - 1.2.4.2 0.0 1567.0
PYH3_k127_4914545_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 8.35e-322 993.0
PYH3_k127_4914545_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 8.076e-314 975.0
PYH3_k127_4914545_3 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 6.637e-262 812.0
PYH3_k127_4914545_4 Belongs to the citrate synthase family K01647 - 2.3.3.1 2.185e-249 776.0
PYH3_k127_4914545_5 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004825 567.0
PYH3_k127_4914545_6 SdhA B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC D which are the membrane components and form cytochrome b556 K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007545 446.0
PYH3_k127_4914545_7 2-phosphosulpholactate phosphatase K05979 - 3.1.3.71 0.000000000000000000000000000000000000000000000000000003115 199.0
PYH3_k127_4914545_8 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.000000000000000000000000000000000000143 143.0
PYH3_k127_4914545_9 Flavinator of succinate dehydrogenase K09159 - - 0.0000000000000000000006057 104.0
PYH3_k127_4914601_0 Belongs to the malic enzymes family K00029 - 1.1.1.40 2.4e-322 1002.0
PYH3_k127_4914601_1 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00124 - - 3.062e-248 775.0
PYH3_k127_4914601_10 D-alanine [D-alanyl carrier protein] ligase activity K00635 - 2.3.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 422.0
PYH3_k127_4914601_11 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 412.0
PYH3_k127_4914601_12 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 367.0
PYH3_k127_4914601_13 SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001078 351.0
PYH3_k127_4914601_14 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 316.0
PYH3_k127_4914601_15 Enoyl-(Acyl carrier protein) reductase K07124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 310.0
PYH3_k127_4914601_16 NnrU protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000578 250.0
PYH3_k127_4914601_17 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.00000000000000000000000000000000000000000000000000000000000000001188 229.0
PYH3_k127_4914601_18 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.00000000000000000000000000000000000000000000000000000000000000003014 232.0
PYH3_k127_4914601_19 Methyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
PYH3_k127_4914601_2 Formate dehydrogenase alpha subunit K00123 - 1.17.1.9 2.524e-246 768.0
PYH3_k127_4914601_20 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000007083 187.0
PYH3_k127_4914601_21 Formate dehydrogenase gamma subunit K00127 - - 0.000000000000000000000000000000000000000000000004934 182.0
PYH3_k127_4914601_22 OmpA family - - - 0.000000000000000000000000000000000000001781 157.0
PYH3_k127_4914601_23 MaoC like domain - - - 0.000000000000000000000000000000000000004269 151.0
PYH3_k127_4914601_24 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.0000000000000000000000000000000001313 137.0
PYH3_k127_4914601_25 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000003659 138.0
PYH3_k127_4914601_26 PFAM FecR protein - - - 0.000000000000000000000001483 108.0
PYH3_k127_4914601_27 - - - - 0.000000000000000000001242 98.0
PYH3_k127_4914601_28 - - - - 0.000000000000000007315 93.0
PYH3_k127_4914601_29 STAS domain K06378 - - 0.000000000000002268 81.0
PYH3_k127_4914601_3 Highly conserved protein containing a thioredoxin domain K06888 - - 1.744e-243 770.0
PYH3_k127_4914601_30 Putative transposase - - - 0.000000000002084 67.0
PYH3_k127_4914601_31 Histidine kinase-like ATPase domain - - - 0.00000000001417 72.0
PYH3_k127_4914601_32 - - - - 0.00003086 53.0
PYH3_k127_4914601_4 Phosphoesterase family - - - 2.067e-197 627.0
PYH3_k127_4914601_5 Pyridoxamine 5'-phosphate K07006 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007094 571.0
PYH3_k127_4914601_6 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346,K03502 GO:0000731,GO:0003674,GO:0003824,GO:0003887,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0006139,GO:0006259,GO:0006281,GO:0006301,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016604,GO:0016607,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019985,GO:0031974,GO:0031981,GO:0032991,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0035770,GO:0036464,GO:0042276,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044451,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0070013,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576,GO:1990904 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001424 510.0
PYH3_k127_4914601_7 Lactonase, 7-bladed beta-propeller - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007372 470.0
PYH3_k127_4914601_8 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006408 480.0
PYH3_k127_4914601_9 ErfK YbiS YcfS YnhG family protein K21470 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 440.0
PYH3_k127_4918336_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 3.565e-286 898.0
PYH3_k127_4918336_1 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.000000000000000007257 83.0
PYH3_k127_4918336_2 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000004304 78.0
PYH3_k127_4925155_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 1.77e-275 860.0
PYH3_k127_4925155_1 amino acid K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002326 584.0
PYH3_k127_4925155_10 Transposase DDE domain group 1 - - - 0.0000000000000000000000000000000000000000001166 160.0
PYH3_k127_4925155_11 Phenylacetate-CoA oxygenase subunit PaaB K02610 - - 0.00000000000000000000000000001239 117.0
PYH3_k127_4925155_12 reverse transcriptase - - - 0.0000000000000000000001653 102.0
PYH3_k127_4925155_13 Transposase DDE domain group 1 - - - 0.0000000008907 63.0
PYH3_k127_4925155_14 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781 - 5.1.2.2 0.00003284 48.0
PYH3_k127_4925155_2 COG1018 Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 K02613 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003012 502.0
PYH3_k127_4925155_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009649 465.0
PYH3_k127_4925155_4 reverse transcriptase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 449.0
PYH3_k127_4925155_5 Belongs to the DapA family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000913 418.0
PYH3_k127_4925155_6 Phenylacetic acid catabolic protein K02611 - 1.14.13.149 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 372.0
PYH3_k127_4925155_7 ATP-binding cassette (ABC) transporters are multidomain membrane proteins, responsible for the controlled efflux and influx of substances (allocrites) across cellular membranes. ATP-binding protein is for coupling the energy of ATP hydrolysis to conformational changes in the transmembrane domains K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007832 366.0
PYH3_k127_4925155_8 Pfam:DUF59 K02612 - - 0.0000000000000000000000000000000000000000000000000000000000002174 224.0
PYH3_k127_4925155_9 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000004289 220.0
PYH3_k127_4940154_0 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.494e-276 860.0
PYH3_k127_4940154_1 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 4.868e-262 833.0
PYH3_k127_4940154_10 Cobalamin biosynthesis protein CobW - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005473 508.0
PYH3_k127_4940154_11 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001114 507.0
PYH3_k127_4940154_12 Cupin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001869 491.0
PYH3_k127_4940154_13 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009881 469.0
PYH3_k127_4940154_14 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004815 437.0
PYH3_k127_4940154_15 succinylglutamate desuccinylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 411.0
PYH3_k127_4940154_16 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001313 411.0
PYH3_k127_4940154_17 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003159 389.0
PYH3_k127_4940154_18 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 371.0
PYH3_k127_4940154_19 LysR substrate binding domain K03566 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 360.0
PYH3_k127_4940154_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.618e-227 711.0
PYH3_k127_4940154_20 Belongs to the 'phage' integrase family. XerC subfamily K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001829 323.0
PYH3_k127_4940154_21 Bacterial lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000501 314.0
PYH3_k127_4940154_22 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002281 289.0
PYH3_k127_4940154_23 Glutathione S-transferase, N-terminal domain K11208 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008149 287.0
PYH3_k127_4940154_24 Ketopantoate reductase PanE/ApbA C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001177 281.0
PYH3_k127_4940154_25 Lipid A biosynthesis acyltransferase K02517 - 2.3.1.241 0.0000000000000000000000000000000000000000000000000000000000000000000000000004334 265.0
PYH3_k127_4940154_26 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006564 243.0
PYH3_k127_4940154_27 Transcriptional regulator K03566 - - 0.00000000000000000000000000000000000000000000000000000000000000000002095 246.0
PYH3_k127_4940154_28 YCII-related domain - - - 0.000000000000000000000000000000000000000000000000000000000000000007666 228.0
PYH3_k127_4940154_29 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.0000000000000000000000000000000000000000000000000000000000000002917 230.0
PYH3_k127_4940154_3 protein related to plant photosystem II stability assembly factor - - - 3.062e-218 683.0
PYH3_k127_4940154_30 Isochorismatase family - - - 0.0000000000000000000000000000000000000000000000000000000000000004866 225.0
PYH3_k127_4940154_31 Protein of unknown function, DUF484 K09921 - - 0.000000000000000000000000000000000000000000000000000000000008967 213.0
PYH3_k127_4940154_32 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000002451 178.0
PYH3_k127_4940154_33 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.000000000000000000000000000000000000000001623 162.0
PYH3_k127_4940154_34 Protein of unknown function (DUF3299) K09950 - - 0.000000000000000000000000000000000004231 145.0
PYH3_k127_4940154_35 PFAM Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000007439 138.0
PYH3_k127_4940154_36 ThiS family K03636 - - 0.000000000000000000000000000000006969 128.0
PYH3_k127_4940154_37 membrane K08972 - - 0.00000000000000000000000000000003722 130.0
PYH3_k127_4940154_38 Protein of unknown function, DUF485 - - - 0.00000000000000000000000000000004039 130.0
PYH3_k127_4940154_39 CoA binding domain - - - 0.0000000000000000000000000000009727 130.0
PYH3_k127_4940154_4 peptidase dimerisation domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 589.0
PYH3_k127_4940154_40 Domain of unknown function (DUF4982) K01190 - 3.2.1.23 0.00000000000000000000006442 104.0
PYH3_k127_4940154_41 Belongs to the sigma-70 factor family. ECF subfamily - - - 0.00000000000000005529 86.0
PYH3_k127_4940154_42 response to antibiotic - - - 0.00002135 54.0
PYH3_k127_4940154_43 - - - - 0.0001189 51.0
PYH3_k127_4940154_5 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002887 565.0
PYH3_k127_4940154_6 Belongs to the ABC transporter superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007713 565.0
PYH3_k127_4940154_7 Soluble lytic murein K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 569.0
PYH3_k127_4940154_8 Belongs to the ABC transporter superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007063 526.0
PYH3_k127_4940154_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000444 506.0
PYH3_k127_4951409_0 PFAM aldehyde oxidase and xanthine dehydrogenase molybdopterin binding K07303 - 1.3.99.16 4.426e-260 821.0
PYH3_k127_4951409_1 alcohol dehydrogenase K19745 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004574 452.0
PYH3_k127_4951409_2 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003245 257.0
PYH3_k127_4951409_3 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000000018 251.0
PYH3_k127_4966823_0 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 317.0
PYH3_k127_4966823_1 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 306.0
PYH3_k127_4966823_2 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000006759 104.0
PYH3_k127_4970584_0 Participates in the degradation of poly-3- hydroxybutyrate (PHB). It works downstream of poly(3- hydroxybutyrate) depolymerase, hydrolyzing D(-)-3-hydroxybutyrate oligomers of various length (3HB-oligomers) into 3HB-monomers K07518 - 3.1.1.22 1.391e-229 733.0
PYH3_k127_4970584_1 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 2.268e-195 621.0
PYH3_k127_4970584_2 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002809 543.0
PYH3_k127_4970584_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002473 435.0
PYH3_k127_4970584_4 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 433.0
PYH3_k127_4970584_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 385.0
PYH3_k127_4970584_6 ABC transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 317.0
PYH3_k127_4970584_7 - - - - 0.000000002124 62.0
PYH3_k127_497944_0 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 GO:0000104,GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009061,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0016627,GO:0016999,GO:0017144,GO:0019752,GO:0022900,GO:0032991,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0045273,GO:0045274,GO:0045281,GO:0045282,GO:0045333,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0070469,GO:0070470,GO:0071704,GO:0071944,GO:0072350,GO:0097159,GO:0098796,GO:0098797,GO:0098803,GO:1901265,GO:1901363,GO:1902494,GO:1990204 1.3.5.1,1.3.5.4 1.715e-249 773.0
PYH3_k127_497944_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 567.0
PYH3_k127_497944_2 GntR family K03710 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 353.0
PYH3_k127_497944_3 TIGRFAM Succinate dehydrogenase, hydrophobic membrane anchor K00242 - - 0.00000000000000000000000000000000000000001372 155.0
PYH3_k127_497944_4 Succinate dehydrogenase, cytochrome b556 subunit K00241 - - 0.0000000000000000000000000000000000000003095 154.0
PYH3_k127_4993868_0 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 9.803e-282 876.0
PYH3_k127_4993868_1 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007121 469.0
PYH3_k127_4993868_2 Transketolase, C-terminal domain K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002915 427.0
PYH3_k127_4993868_3 MTH538 TIR-like domain (DUF1863) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 428.0
PYH3_k127_4993868_4 PFAM Nitroreductase - - - 0.000000000000000000000000000000000000000000000000000000000000002127 224.0
PYH3_k127_4993868_5 COG4635 Flavodoxin K00230 - 1.3.5.3 0.00000000000000000000000000000000000000004557 161.0
PYH3_k127_4993868_6 DNA mediated transformation - - - 0.000000000000000000000000000000000001278 147.0
PYH3_k127_4993868_7 FMN binding - - - 0.0000000000000000000000000000006389 128.0
PYH3_k127_5001249_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.777e-284 901.0
PYH3_k127_5001249_1 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 1.714e-198 627.0
PYH3_k127_5001249_10 endonuclease III K01247 - 3.2.2.21 0.0000000000000000000000000000000000000000000000000000000000000000000225 240.0
PYH3_k127_5001249_11 SpoU rRNA Methylase family K02533 - - 0.0000000000000000000000000000000000000000000000000000000000000001368 229.0
PYH3_k127_5001249_12 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.0000000000000000000000000000000000000000000000000000000000001811 221.0
PYH3_k127_5001249_13 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000002423 183.0
PYH3_k127_5001249_14 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.000000000000000000000000000000000000002526 155.0
PYH3_k127_5001249_15 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000001617 143.0
PYH3_k127_5001249_16 peptidyl-prolyl K03775 - 5.2.1.8 0.00000000000000000000000000000000003095 141.0
PYH3_k127_5001249_17 - - - - 0.00000000498 65.0
PYH3_k127_5001249_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000707 560.0
PYH3_k127_5001249_3 PFAM Cupin 4 family protein K18850 - 1.14.11.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005826 389.0
PYH3_k127_5001249_4 Bacterial transferase hexapeptide (six repeats) K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001353 377.0
PYH3_k127_5001249_5 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001928 372.0
PYH3_k127_5001249_6 Sugar kinases ribokinase family K00874 - 2.7.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 349.0
PYH3_k127_5001249_7 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000154 274.0
PYH3_k127_5001249_8 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000036 250.0
PYH3_k127_5001249_9 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000004714 246.0
PYH3_k127_5008853_0 Belongs to the malate synthase family K01638 - 2.3.3.9 1.53e-282 874.0
PYH3_k127_5008853_1 Chromate K07240 - - 1.251e-203 643.0
PYH3_k127_5008853_10 Acetyltransferase (GNAT) domain - - - 0.0004646 47.0
PYH3_k127_5008853_11 COG1670 Acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.0005208 49.0
PYH3_k127_5008853_2 belongs to the aldehyde dehydrogenase family K00128,K00154 - 1.2.1.3,1.2.1.68 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006695 583.0
PYH3_k127_5008853_3 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 542.0
PYH3_k127_5008853_4 Superoxide dismutase K04564 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 344.0
PYH3_k127_5008853_5 Chromate resistance - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000111 280.0
PYH3_k127_5008853_6 Chromate resistance exported protein - - - 0.00000000000000000000000000000000000000000000000000000000006172 207.0
PYH3_k127_5008853_7 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000003815 184.0
PYH3_k127_5008853_8 Haloacid dehalogenase, type II K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000003043 181.0
PYH3_k127_5008853_9 - - - - 0.0000000001824 64.0
PYH3_k127_5056163_0 Evidence 2b Function of strongly homologous gene - - - 3.957e-242 756.0
PYH3_k127_5056163_1 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002018 404.0
PYH3_k127_5085109_0 Two component transcriptional regulator, winged helix family K02483 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001273 254.0
PYH3_k127_5085109_1 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000000000000000000000000000000004601 221.0
PYH3_k127_5085109_2 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000000000000000000000000000000000000000003902 196.0
PYH3_k127_5085109_3 Transporter associated domain K03699 - - 0.000000000000000000000000000000000000000000000001192 175.0
PYH3_k127_5085109_4 Prokaryotic cytochrome b561 - - - 0.00000000000000000000000000000000000000000000000223 178.0
PYH3_k127_5085109_5 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000004971 180.0
PYH3_k127_5085109_6 Histidine triad (Hit) protein - - - 0.00000000000000000000000000000000000000007145 159.0
PYH3_k127_5085109_7 Uncharacterized ACR, COG1993 K09137 - - 0.00000000000000000000000000000000000782 142.0
PYH3_k127_5085109_8 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.00000000000000000000005942 103.0
PYH3_k127_5085109_9 Peptidase propeptide and YPEB domain - - - 0.00000000003364 69.0
PYH3_k127_5088860_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.096e-219 688.0
PYH3_k127_5088860_1 TRAP-type C4-dicarboxylate transport system periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005682 505.0
PYH3_k127_5088860_2 racemase activity, acting on amino acids and derivatives - - - 0.000000000000000000000000000000000000000000000000000000000000000003782 232.0
PYH3_k127_5088860_3 Tripartite ATP-independent periplasmic transporter DctQ component - - - 0.0000000000000000000000000000000000000000000000000000002957 198.0
PYH3_k127_5088860_4 5-oxoprolinase K01469 - 3.5.2.9 0.00000000000000000000000000009519 115.0
PYH3_k127_5091221_0 Transketolase, pyrimidine binding domain K21417 - - 1.393e-194 609.0
PYH3_k127_5091221_1 Dehydrogenase E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005709 564.0
PYH3_k127_5091221_2 PFAM alpha beta hydrolase fold K00627 - 2.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 548.0
PYH3_k127_5091221_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003281 518.0
PYH3_k127_5091221_4 Diacylglycerol kinase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 484.0
PYH3_k127_5091221_5 lipoate-protein ligase A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001194 252.0
PYH3_k127_5096955_0 Dehydratase family K13875 - 4.2.1.25 1.038e-302 935.0
PYH3_k127_5096955_1 amine dehydrogenase activity - - - 1.229e-297 943.0
PYH3_k127_5096955_10 PFAM Phage derived protein Gp49-like (DUF891) - - - 0.0000000000000000000000000000003882 123.0
PYH3_k127_5096955_11 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000008928 121.0
PYH3_k127_5096955_12 Helix-turn-helix domain - - - 0.000000000000000000000000004885 113.0
PYH3_k127_5096955_13 Tetratricopeptide repeat - - - 0.000000000000000002647 97.0
PYH3_k127_5096955_14 Binding-protein-dependent transport system inner membrane component K02026 - - 0.00000000000002369 74.0
PYH3_k127_5096955_2 Bacterial extracellular solute-binding protein K02027 - - 4.92e-216 677.0
PYH3_k127_5096955_3 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009621 513.0
PYH3_k127_5096955_4 ABC-type sugar K02025,K10237 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006495 497.0
PYH3_k127_5096955_5 Belongs to the LDH2 MDH2 oxidoreductase family K00016 - 1.1.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006369 441.0
PYH3_k127_5096955_6 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007067 431.0
PYH3_k127_5096955_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005135 343.0
PYH3_k127_5096955_8 Cyclophilin type peptidyl-prolyl cis-trans isomerase K01802,K03767 - 5.2.1.8 0.00000000000000000000000000000000000000000000274 176.0
PYH3_k127_5096955_9 Protease prsW family - - - 0.000000000000000000000000000000000000001567 160.0
PYH3_k127_5114180_0 Isocitrate lyase K01637 - 4.1.3.1 5.911e-251 778.0
PYH3_k127_5114180_1 DNA polymerase K00986 - 2.7.7.49 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001353 273.0
PYH3_k127_5114180_2 COG1961 Site-specific recombinases, DNA invertase Pin homologs K06400 - - 0.00000000000000000000000000000000000000000000000000000000000000002442 226.0
PYH3_k127_5114180_3 - - - - 0.000000000000000000000002045 110.0
PYH3_k127_5114180_4 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.000000000000000000000007657 102.0
PYH3_k127_5114180_5 Ribbon-helix-helix protein, copG family - - - 0.00000000000002779 77.0
PYH3_k127_5151734_0 Belongs to the NiCoT transporter (TC 2.A.52) family K07241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000343 342.0
PYH3_k127_5151734_1 Transcriptional regulator K07722 - - 0.000000000000000000000000000000000000000000000000000000000004339 212.0
PYH3_k127_5151734_2 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000001159 128.0
PYH3_k127_5151734_3 Prokaryotic cytochrome b561 - - - 0.00000000000000000000006215 103.0
PYH3_k127_5151734_4 lipolytic protein G-D-S-L family - - - 0.00000000000000001082 96.0
PYH3_k127_5166048_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1213.0
PYH3_k127_5166048_1 Required for chromosome condensation and partitioning K03529 - - 0.0 1125.0
PYH3_k127_5166048_10 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006686 500.0
PYH3_k127_5166048_11 C-terminal region of band_7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001773 469.0
PYH3_k127_5166048_12 Type II/IV secretion system protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 466.0
PYH3_k127_5166048_13 Metallopeptidase family M24 K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008151 449.0
PYH3_k127_5166048_14 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003037 436.0
PYH3_k127_5166048_15 zinc metalloprotease K11749 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002723 443.0
PYH3_k127_5166048_16 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 419.0
PYH3_k127_5166048_17 COG2230 Cyclopropane fatty acid synthase and related methyltransferases K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002504 421.0
PYH3_k127_5166048_18 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 409.0
PYH3_k127_5166048_19 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 422.0
PYH3_k127_5166048_2 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 5e-324 1015.0
PYH3_k127_5166048_20 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 398.0
PYH3_k127_5166048_21 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002202 403.0
PYH3_k127_5166048_22 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 395.0
PYH3_k127_5166048_23 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002619 387.0
PYH3_k127_5166048_24 CoA-transferase family III K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 376.0
PYH3_k127_5166048_25 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 368.0
PYH3_k127_5166048_26 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002178 349.0
PYH3_k127_5166048_27 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009054 347.0
PYH3_k127_5166048_28 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 346.0
PYH3_k127_5166048_29 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 336.0
PYH3_k127_5166048_3 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 5.452e-289 902.0
PYH3_k127_5166048_30 Phosphorylase superfamily K00772,K03815 - 2.4.2.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001854 318.0
PYH3_k127_5166048_31 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001599 285.0
PYH3_k127_5166048_32 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 283.0
PYH3_k127_5166048_33 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005947 273.0
PYH3_k127_5166048_34 Phosphoglycerate mutase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001758 240.0
PYH3_k127_5166048_35 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.000000000000000000000000000000000000000000000000000000000000000000136 232.0
PYH3_k127_5166048_36 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000002321 231.0
PYH3_k127_5166048_37 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000003825 221.0
PYH3_k127_5166048_38 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.00000000000000000000000000000000000000000000000000000000002201 209.0
PYH3_k127_5166048_39 Belongs to the skp family K06142 - - 0.000000000000000000000000000000000000000000000000000003568 196.0
PYH3_k127_5166048_4 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 7.486e-286 899.0
PYH3_k127_5166048_40 SpoU rRNA Methylase family K03437 - - 0.0000000000000000000000000000000000000000000000007189 184.0
PYH3_k127_5166048_41 Oligoketide cyclase lipid transport protein - - - 0.000000000000000000000000000000000000000001066 161.0
PYH3_k127_5166048_42 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000003718 162.0
PYH3_k127_5166048_43 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000149 152.0
PYH3_k127_5166048_44 Membrane protein implicated in regulation of membrane protease activity - - - 0.00000000000000000000000000000001195 132.0
PYH3_k127_5166048_45 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.00000000000000000000000000002147 131.0
PYH3_k127_5166048_46 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000003286 84.0
PYH3_k127_5166048_47 Domain of unknown function (DUF4124) - - - 0.00000000000000003639 90.0
PYH3_k127_5166048_48 Protein of unknown function (DUF1847) - - - 0.00000000000000004417 88.0
PYH3_k127_5166048_49 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000008412 79.0
PYH3_k127_5166048_5 ABC transporter C-terminal domain K06158 - - 1.948e-260 816.0
PYH3_k127_5166048_50 Belongs to the UPF0125 (RnfH) family K09801 - - 0.0000000000001194 75.0
PYH3_k127_5166048_51 Protein of unknown function (DUF1847) - - - 0.000000001951 62.0
PYH3_k127_5166048_53 Protein of unknown function (DUF1847) - - - 0.0005809 42.0
PYH3_k127_5166048_6 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.983e-241 755.0
PYH3_k127_5166048_7 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 526.0
PYH3_k127_5166048_8 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007039 526.0
PYH3_k127_5166048_9 Aminoglycoside phosphotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 501.0
PYH3_k127_5166802_0 Heat shock 70 kDa protein K04043 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.0 1054.0
PYH3_k127_5166802_1 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000619 604.0
PYH3_k127_5166802_10 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000009101 229.0
PYH3_k127_5166802_11 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000000000000000004608 196.0
PYH3_k127_5166802_12 Biopolymer transport protein, ExbD K03559 - - 0.00000000000000000000000000000000000000003469 156.0
PYH3_k127_5166802_13 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.0000000000000000000000000000000000006002 151.0
PYH3_k127_5166802_14 Glycine zipper 2TM domain - - - 0.00000000000000000000000000000003937 138.0
PYH3_k127_5166802_15 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000005284 124.0
PYH3_k127_5166802_16 Low molecular weight phosphotyrosine protein phosphatase K03741 - 1.20.4.1 0.000000000000000000000001234 109.0
PYH3_k127_5166802_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 546.0
PYH3_k127_5166802_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002886 478.0
PYH3_k127_5166802_4 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008198 462.0
PYH3_k127_5166802_5 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008839,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0019752,GO:0019877,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576 1.17.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001064 381.0
PYH3_k127_5166802_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002205 310.0
PYH3_k127_5166802_7 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001095 275.0
PYH3_k127_5166802_8 Biopolymer transport K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004854 271.0
PYH3_k127_5166802_9 Platelet-activating factor acetylhydrolase plasma intracellular isoform II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001566 259.0
PYH3_k127_5243380_0 MotA/TolQ/ExbB proton channel family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 301.0
PYH3_k127_5243380_1 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.00000000000000000000000000000000000000000000000000000000000000000004048 239.0
PYH3_k127_5243380_2 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000000000006395 222.0
PYH3_k127_5243380_3 Biopolymer transport protein ExbD/TolR - - - 0.000000000000000000000000000000000000000000000000000000002162 204.0
PYH3_k127_5256776_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 4.358e-264 826.0
PYH3_k127_5256776_1 Glycolate oxidase subunit GlcD K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 1.631e-230 730.0
PYH3_k127_5256776_10 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002153 298.0
PYH3_k127_5256776_11 Phosphate acyltransferases K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 291.0
PYH3_k127_5256776_12 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009953 298.0
PYH3_k127_5256776_13 Adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004897 279.0
PYH3_k127_5256776_14 response regulator K15012 - - 0.000000000000000000000000000000000000000000000000000000000002571 214.0
PYH3_k127_5256776_15 COG1226 Kef-type K transport systems - - - 0.00000000000000000000000000000000000000000000000000000002811 201.0
PYH3_k127_5256776_16 PFAM ATP-binding region ATPase domain protein K15011 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000274 201.0
PYH3_k127_5256776_17 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.00000000000000000000000000000000000000000000001149 183.0
PYH3_k127_5256776_18 Protein of unknown function (DUF1203) - - - 0.0000000000000000000000000000000000000001452 155.0
PYH3_k127_5256776_19 Putative auto-transporter adhesin, head GIN domain - - - 0.0000000000000000000000000000001679 133.0
PYH3_k127_5256776_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 3.56e-225 715.0
PYH3_k127_5256776_20 Mitomycin resistance protein K07343 - - 0.0000000000000000000005354 104.0
PYH3_k127_5256776_21 - - - - 0.00000000000000000002129 100.0
PYH3_k127_5256776_22 Dodecin K09165 - - 0.0000000000000000001575 92.0
PYH3_k127_5256776_23 regulator - - - 0.0000000002982 69.0
PYH3_k127_5256776_3 FAD linked oxidases, C-terminal domain K00102,K03777 - 1.1.2.4,1.1.5.12 8.884e-224 702.0
PYH3_k127_5256776_4 Glycolate oxidase, iron-sulfur subunit K11473 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005071 604.0
PYH3_k127_5256776_5 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006602 581.0
PYH3_k127_5256776_6 Mandelate racemase / muconate lactonizing enzyme, N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008583 522.0
PYH3_k127_5256776_7 AlkA N-terminal domain K13529 - 3.2.2.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002666 510.0
PYH3_k127_5256776_8 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004943 448.0
PYH3_k127_5256776_9 FAD binding K11472 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003452 441.0
PYH3_k127_525949_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 400.0
PYH3_k127_525949_1 KR domain K00046 - 1.1.1.69 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002663 385.0
PYH3_k127_525949_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.000000000000000000000000000000000000000000000000000000000000000000001228 236.0
PYH3_k127_5266920_0 Alpha amylase, catalytic domain K01176 - 3.2.1.1 2.858e-274 853.0
PYH3_k127_5266920_1 Maltose transport system permease protein MalF P2 domain K10109 - - 8.556e-242 759.0
PYH3_k127_5266920_2 Bacterial extracellular solute-binding protein K10108 - - 1.327e-220 689.0
PYH3_k127_5266920_3 Binding-protein-dependent transport system inner membrane component K10110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 527.0
PYH3_k127_5266920_4 hydrolase activity, hydrolyzing O-glycosyl compounds K01176,K01200 - 3.2.1.1,3.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005509 434.0
PYH3_k127_5266920_5 ABC transporter K10111 - - 0.0000000000000000000000000000000000000000000000000003061 187.0
PYH3_k127_5266920_6 Bacterial pullanase-associated domain - - - 0.000003062 52.0
PYH3_k127_5273229_0 Cytochrome c-type biogenesis protein CcmF K02198 - - 4.824e-314 972.0
PYH3_k127_5273229_1 heat shock protein binding - - - 5.794e-266 834.0
PYH3_k127_5273229_2 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004258 433.0
PYH3_k127_5273229_3 Cytochrome c-type biogenesis protein K02200 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002062 301.0
PYH3_k127_5273229_4 oxidoreductase DsbE K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003644 241.0
PYH3_k127_5273229_5 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000001427 238.0
PYH3_k127_5273229_6 His Kinase A (phosphoacceptor) domain K02484,K07645 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000001393 231.0
PYH3_k127_5273229_7 Psort location Cytoplasmic, score 9.97 K07666 - - 0.000000000000000000000000000000000000000000000000000000000002441 219.0
PYH3_k127_5273229_8 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000001535 210.0
PYH3_k127_5273229_9 subunit of a heme lyase K02200 - - 0.00000000000000000000000000000000000000007624 158.0
PYH3_k127_5295558_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.807e-239 758.0
PYH3_k127_5295558_1 COG0402 Cytosine deaminase and related metal-dependent hydrolases K01487 - 3.5.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 601.0
PYH3_k127_5295558_10 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000004181 151.0
PYH3_k127_5295558_11 - - - - 0.00000000000000000000007676 104.0
PYH3_k127_5295558_12 Dienelactone hydrolase family - - - 0.00000000007907 70.0
PYH3_k127_5295558_13 Tripartite ATP-independent periplasmic transporters, DctQ component K21394 - - 0.0008015 48.0
PYH3_k127_5295558_2 Pfam:DUF989 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007893 581.0
PYH3_k127_5295558_3 LysR family K04761 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 470.0
PYH3_k127_5295558_4 signal transduction protein containing sensor and EAL - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004456 319.0
PYH3_k127_5295558_5 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004863 318.0
PYH3_k127_5295558_6 Carboxylesterase family K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001003 273.0
PYH3_k127_5295558_7 Basic membrane lipoprotein K02058 - - 0.00000000000000000000000000000000000000000000000000000000000000002143 226.0
PYH3_k127_5295558_8 endoribonuclease K09022 - 3.5.99.10 0.000000000000000000000000000000000000000000000005917 174.0
PYH3_k127_5295558_9 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000007471 153.0
PYH3_k127_5298661_0 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004346 512.0
PYH3_k127_5298661_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000006571 238.0
PYH3_k127_5298661_2 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000009192 206.0
PYH3_k127_5298661_3 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000002826 99.0
PYH3_k127_5315009_0 type II secretion system protein E K02454 - - 3.485e-207 657.0
PYH3_k127_5315009_1 Hydroxyphenylpyruvate dioxygenase, HPPD, N-terminal K00457 - 1.13.11.27 2.665e-203 639.0
PYH3_k127_5315009_10 Type II secretion system (T2SS), protein N K02463 - - 0.0000000000000000000000000000000441 135.0
PYH3_k127_5315009_11 general secretion pathway protein K02457 - - 0.00000000000000000000000253 108.0
PYH3_k127_5315009_12 General secretion pathway K02462 - - 0.0000000000000000009169 92.0
PYH3_k127_5315009_13 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000965 86.0
PYH3_k127_5315009_14 Prokaryotic N-terminal methylation motif K02459 - - 0.000000000000000001364 93.0
PYH3_k127_5315009_15 Type II secretion system (T2SS), protein I K02458 - - 0.000000000000000004347 93.0
PYH3_k127_5315009_16 General secretion pathway protein L K02461 - - 0.00000000000000006133 94.0
PYH3_k127_5315009_17 general secretion pathway protein K02452 - - 0.000000000002887 76.0
PYH3_k127_5315009_18 helix_turn_helix ASNC type K03719 GO:0001101,GO:0003674,GO:0003676,GO:0003677,GO:0003700,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010033,GO:0010243,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0042221,GO:0043200,GO:0043565,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1901698,GO:1901700,GO:1903506,GO:2000112,GO:2001141 - 0.000000000005184 71.0
PYH3_k127_5315009_2 general secretion pathway protein D K02453 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 617.0
PYH3_k127_5315009_3 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003601 512.0
PYH3_k127_5315009_4 General secretion pathway protein F K02455 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001622 428.0
PYH3_k127_5315009_5 LytTr DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008525 331.0
PYH3_k127_5315009_6 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009102 299.0
PYH3_k127_5315009_7 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000002463 237.0
PYH3_k127_5315009_8 general secretion pathway protein G K02456 - - 0.000000000000000000000000000000000000000000000000000000000788 206.0
PYH3_k127_5315009_9 Type II secretion system (T2SS), protein K K02460 - - 0.00000000000000000000000000000000000000000000000000001676 201.0
PYH3_k127_5336258_0 PIN domain - - - 0.000000000000000000000000000008576 126.0
PYH3_k127_5336258_1 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.00000000000000000001332 94.0
PYH3_k127_5348622_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 6.799e-203 651.0
PYH3_k127_5348622_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003253 509.0
PYH3_k127_5348622_2 COG3245 Cytochrome c5 - - - 0.0000000000000000000000000000000000000000000000000000000000000000001853 243.0
PYH3_k127_5348622_3 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.00000000000000000000000000000000000000000000000000000001438 207.0
PYH3_k127_5348622_4 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000003293 164.0
PYH3_k127_5348622_5 Outer membrane receptor proteins mostly Fe transport K02014 - - 0.000000000000000000000000000008235 122.0
PYH3_k127_5348622_6 TonB family K03832 - - 0.000000000000000009938 90.0
PYH3_k127_5348622_7 Type II transport protein GspH K08084 - - 0.00000000000007472 80.0
PYH3_k127_5349552_0 Protein of unknown function (DUF1298) - - - 1.72e-237 746.0
PYH3_k127_5349552_1 - - - - 0.0000682 47.0
PYH3_k127_5407753_0 surface antigen variable number repeat protein K07001 - - 4.981e-294 919.0
PYH3_k127_5407753_1 Phospholipase D. Active site motifs. K06132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 543.0
PYH3_k127_5407753_2 Domain of unknown function (DUF4105) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 392.0
PYH3_k127_5407753_3 Surface antigen - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005477 335.0
PYH3_k127_5407753_4 Las17-binding protein actin regulator - - - 0.000000000000000000000000000000000000000000000000001649 190.0
PYH3_k127_5407753_5 Domain of unknown function (DUF4136) - - - 0.0000000000000000000000000000000000000000000537 168.0
PYH3_k127_5407753_6 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000105 132.0
PYH3_k127_5407753_7 Sodium Bile acid symporter family K03453 - - 0.0002902 47.0
PYH3_k127_5412861_0 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 528.0
PYH3_k127_5412861_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990,K13926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 462.0
PYH3_k127_5412861_2 Biotin-lipoyl like K01993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009409 321.0
PYH3_k127_5412861_3 tetR family - - - 0.0000000000000000000000000000000000000000000000000000001116 200.0
PYH3_k127_5481096_0 PFAM permease K07089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 274.0
PYH3_k127_5481096_1 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000268 188.0
PYH3_k127_5481096_2 - - - - 0.000000000000000000000000000000000000000001092 162.0
PYH3_k127_5512573_0 CoA binding domain - - - 6.816e-296 922.0
PYH3_k127_5512573_1 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
PYH3_k127_5512573_2 Thioesterase - - - 0.00000000000000002031 83.0
PYH3_k127_5515248_0 cytosine deaminase K01485 - 3.5.4.1 3.06e-228 711.0
PYH3_k127_5515248_1 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008638 448.0
PYH3_k127_5515248_10 Protein of unknown function (DUF423) - - - 0.00000000000000000000000000000000000002007 151.0
PYH3_k127_5515248_11 BON domain - - - 0.00000000000000000000000000000000000034 156.0
PYH3_k127_5515248_12 Protein of unknown function (DUF3144) - - - 0.00000002376 67.0
PYH3_k127_5515248_2 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009111 441.0
PYH3_k127_5515248_3 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 398.0
PYH3_k127_5515248_4 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 399.0
PYH3_k127_5515248_5 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006424 368.0
PYH3_k127_5515248_6 Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate K00761 GO:0003674,GO:0003824,GO:0004849,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006206,GO:0006213,GO:0006220,GO:0006221,GO:0006222,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009112,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009129,GO:0009130,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009173,GO:0009174,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0018130,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0043094,GO:0043097,GO:0043174,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046049,GO:0046131,GO:0046132,GO:0046134,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000556 354.0
PYH3_k127_5515248_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 297.0
PYH3_k127_5515248_8 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001091 291.0
PYH3_k127_5515248_9 - - - - 0.000000000000000000000000000000000000000000000000000000003016 208.0
PYH3_k127_5539811_0 Site-specific recombinase, DNA invertase Pin - - - 5.31e-272 853.0
PYH3_k127_5539811_1 PFAM Integrase catalytic - - - 2.673e-270 838.0
PYH3_k127_5539811_2 PFAM IstB domain protein ATP-binding protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002605 285.0
PYH3_k127_5539811_3 Transposase - - - 0.0000000000000000000000000000000000000000000000000003042 187.0
PYH3_k127_5539811_4 PFAM IstB domain protein ATP-binding protein - - - 0.000000000000000000000000000000000000000000000001921 176.0
PYH3_k127_5539811_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000002932 169.0
PYH3_k127_5539811_6 - - - - 0.00000000009075 69.0
PYH3_k127_5573148_0 Belongs to the thiolase family K00626,K00632 - 2.3.1.16,2.3.1.9 6.439e-201 631.0
PYH3_k127_5573148_1 TAP-like protein K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 547.0
PYH3_k127_5573148_10 Putative serine dehydratase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 364.0
PYH3_k127_5573148_11 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 327.0
PYH3_k127_5573148_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000009238 235.0
PYH3_k127_5573148_13 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000000000001427 221.0
PYH3_k127_5573148_14 protocatechuate 3,4-dioxygenase K00448 - 1.13.11.3 0.00000000000000000000000000000000000000000000000000000000000007975 220.0
PYH3_k127_5573148_15 carbon monoxide dehydrogenase K09386 - - 0.0000000000000000000000000000000000000000000005671 173.0
PYH3_k127_5573148_2 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 520.0
PYH3_k127_5573148_3 3-carboxy-cis,cis-muconate cycloisomerase K01857 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004554 505.0
PYH3_k127_5573148_4 VWA domain containing CoxE-like protein K07161 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005323 464.0
PYH3_k127_5573148_5 Bacterial capsule synthesis protein PGA_cap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 448.0
PYH3_k127_5573148_6 AAA domain (dynein-related subfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 425.0
PYH3_k127_5573148_7 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 404.0
PYH3_k127_5573148_8 Malonyl-CoA decarboxylase K01578 - 4.1.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002442 404.0
PYH3_k127_5573148_9 protocatechuate 3,4-dioxygenase beta subunit K00449 - 1.13.11.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005944 362.0
PYH3_k127_5645383_0 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 3.308e-289 903.0
PYH3_k127_5645383_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.639e-238 742.0
PYH3_k127_5645383_2 PD-(D/E)XK nuclease superfamily K16899 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004688 461.0
PYH3_k127_5645383_3 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 403.0
PYH3_k127_5645383_4 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 405.0
PYH3_k127_5645383_5 MatE K03327 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 373.0
PYH3_k127_5645383_6 UPF0114 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003547 272.0
PYH3_k127_5645383_7 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000000002798 185.0
PYH3_k127_5645383_8 Ribosomal protein L31 K02909 - - 0.00000000000000000000000000000000872 130.0
PYH3_k127_5645383_9 A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit contributes ATPase, 3'-5' helicase, exonuclease activity and loads RecA onto ssDNA K03582,K16898 - 3.1.11.5,3.6.4.12 0.0000000000000002601 81.0
PYH3_k127_5669440_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1308.0
PYH3_k127_5669440_1 ATPase MipZ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001495 258.0
PYH3_k127_5669440_2 PQ loop repeat K15383 - - 0.000000000000000000008115 94.0
PYH3_k127_5686424_0 glutamate synthase K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2516.0
PYH3_k127_5686424_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 3.2e-256 796.0
PYH3_k127_5686424_2 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009603 537.0
PYH3_k127_5686424_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009625 377.0
PYH3_k127_5686424_4 PFAM Ribulose bisphosphate carboxylase large chain K01601 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004132 341.0
PYH3_k127_5686424_5 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003245 257.0
PYH3_k127_5686424_6 Cupin 2, conserved barrel domain protein K11312 - - 0.000000000000000000000000000000000000000000000004964 177.0
PYH3_k127_5686424_7 COG2010 Cytochrome c, mono- and diheme variants - - - 0.000000000000002233 80.0
PYH3_k127_5686424_8 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000001773 51.0
PYH3_k127_5717989_0 Major Facilitator - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000023 437.0
PYH3_k127_5717989_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000277 364.0
PYH3_k127_5717989_2 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 324.0
PYH3_k127_5717989_3 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000742 306.0
PYH3_k127_5717989_5 RNA-directed DNA polymerase K00986 - 2.7.7.49 0.00000000000000002947 84.0
PYH3_k127_5769706_0 Alcohol dehydrogenase GroES-like domain K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001448 473.0
PYH3_k127_5769706_1 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002956 448.0
PYH3_k127_5769706_2 Cupin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003096 235.0
PYH3_k127_58078_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008237,GO:0009056,GO:0009057,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0030163,GO:0042623,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575 - 0.0 1051.0
PYH3_k127_58078_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 1.321e-195 619.0
PYH3_k127_58078_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 317.0
PYH3_k127_58078_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004598 291.0
PYH3_k127_58078_4 PFAM EAL domain - - - 0.0000000000000000000000000000185 135.0
PYH3_k127_5898521_0 PFAM Prokaryotic protein of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007699 542.0
PYH3_k127_5898521_1 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 399.0
PYH3_k127_5898521_2 Branched-chain amino acid transport system / permease component K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 378.0
PYH3_k127_5898521_3 KR domain K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001265 313.0
PYH3_k127_5898521_4 amine dehydrogenase activity - - - 0.000000000000000000000001536 109.0
PYH3_k127_5911976_0 Putative amidoligase enzyme (DUF2126) - - - 0.0 1620.0
PYH3_k127_5911976_1 PFAM 20S proteasome, A and B subunits K07395 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001859 364.0
PYH3_k127_5911976_2 protein conserved in bacteria - - - 0.0000000000001013 71.0
PYH3_k127_5965146_0 40-residue YVTN family beta-propeller - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 342.0
PYH3_k127_5965146_1 PFAM multicopper oxidase type K04753,K08100,K14588 - 1.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001742 312.0
PYH3_k127_5965146_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000268 231.0
PYH3_k127_5965146_3 Ankyrin repeats (3 copies) K06867,K21440 - - 0.00000000000000000000000000000000000000000000000000006276 194.0
PYH3_k127_5965146_4 PQQ enzyme repeat - - - 0.000000000000000000000000000000009853 132.0
PYH3_k127_6042427_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 0.0 1134.0
PYH3_k127_6042427_1 Acyl-CoA dehydrogenase N terminal - - - 2.686e-271 850.0
PYH3_k127_6042427_10 Enoyl-(Acyl carrier protein) reductase K13775 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005822 407.0
PYH3_k127_6042427_11 PFAM NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K18006 - 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004428 389.0
PYH3_k127_6042427_12 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K18007 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.12.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000149 337.0
PYH3_k127_6042427_13 Outer membrane usher protein K07347 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 364.0
PYH3_k127_6042427_14 PFAM Enoyl-CoA hydratase isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009934 308.0
PYH3_k127_6042427_15 Subtilase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009114 318.0
PYH3_k127_6042427_16 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 279.0
PYH3_k127_6042427_17 PFAM Extradiol ring-cleavage dioxygenase, class III K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000819 271.0
PYH3_k127_6042427_18 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000000000000000000002452 244.0
PYH3_k127_6042427_19 Class II Aldolase and Adducin N-terminal domain K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000000000000000004703 239.0
PYH3_k127_6042427_2 Respiratory-chain NADH dehydrogenase K18005 - 1.12.1.2 1.405e-270 846.0
PYH3_k127_6042427_20 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000001458 210.0
PYH3_k127_6042427_21 PFAM regulatory protein TetR - - - 0.0000000000000000000000000000000000000000000000000000000003223 211.0
PYH3_k127_6042427_22 Tellurite resistance protein TehB - - - 0.00000000000000000000000000000000000000000000000000000000687 207.0
PYH3_k127_6042427_23 of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000002787 202.0
PYH3_k127_6042427_24 GDSL-like Lipase/Acylhydrolase family - - - 0.000000000000000000000000000000000000000000001067 174.0
PYH3_k127_6042427_25 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000001456 168.0
PYH3_k127_6042427_26 TraB family K09973 - - 0.00000000000000000000000000000000000000000003565 172.0
PYH3_k127_6042427_27 PFAM DoxX family protein K15977 - - 0.000000000000000000000000000000000000000001055 160.0
PYH3_k127_6042427_28 hydrogenase maturation protease - - - 0.00000000000000000000000000000000001974 140.0
PYH3_k127_6042427_3 Acyl-CoA synthetase (NDP forming) K09181 - - 1.399e-259 829.0
PYH3_k127_6042427_30 Protein of unknown function (DUF2892) - - - 0.00000000000000000000000004475 110.0
PYH3_k127_6042427_31 assembly chaperone K07346 - - 0.0000000000000000000000008769 114.0
PYH3_k127_6042427_32 dksA traR - - - 0.0000000000000000001135 94.0
PYH3_k127_6042427_33 Spore Coat Protein U domain - - - 0.0000000000000000001931 94.0
PYH3_k127_6042427_34 Secreted protein - - - 0.000000000000000006671 90.0
PYH3_k127_6042427_35 PFAM Glycosyl transferases group 1 K12995 - 2.4.1.348 0.0000000000000001907 87.0
PYH3_k127_6042427_36 protein conserved in bacteria - - - 0.000000000000009297 77.0
PYH3_k127_6042427_37 Spore Coat Protein U domain - - - 0.00000000000001117 81.0
PYH3_k127_6042427_4 CHAT domain - - - 9.625e-257 822.0
PYH3_k127_6042427_5 Belongs to the NiFe NiFeSe hydrogenase large subunit family K00436 - 1.12.1.2 1.08e-248 777.0
PYH3_k127_6042427_6 Belongs to the thiolase family K00632 - 2.3.1.16 7.108e-202 634.0
PYH3_k127_6042427_7 Glycosyl transferase family 1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 572.0
PYH3_k127_6042427_8 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005437 445.0
PYH3_k127_6042427_9 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 444.0
PYH3_k127_6062023_0 glycine betaine K05845 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 460.0
PYH3_k127_6062023_1 Ornithine cyclodeaminase/mu-crystallin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 453.0
PYH3_k127_6062023_2 COG3221 ABC-type phosphate phosphonate transport system, periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000177 223.0
PYH3_k127_6062023_3 Histidine ammonia-lyase K01745 - 4.3.1.3 0.0000000000000000000000000000003074 126.0
PYH3_k127_6078370_0 DNA helicase K03657 - 3.6.4.12 8.901e-295 919.0
PYH3_k127_6078370_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine - - - 4.332e-223 700.0
PYH3_k127_6078370_10 - - - - 0.0000000000000000000000000000000000000001729 158.0
PYH3_k127_6078370_11 Cro/C1-type HTH DNA-binding domain - - - 0.00000000000000000000000000000000001312 139.0
PYH3_k127_6078370_12 Addiction module toxin, RelE StbE family K07334 - - 0.0000000000000000000000000000000000327 136.0
PYH3_k127_6078370_13 HIUase/Transthyretin family K07127 - 3.5.2.17 0.000000000000000000000000000005114 124.0
PYH3_k127_6078370_14 Type II secretion system (T2SS), protein F K02455,K12278 - - 0.000000000000000000000000000008781 119.0
PYH3_k127_6078370_15 Prokaryotic N-terminal methylation motif K10924 - - 0.000000000000000000000009019 107.0
PYH3_k127_6078370_16 Transposase IS200 like K07491 - - 0.0000000000000000000003485 100.0
PYH3_k127_6078370_17 Protein of unknown function (DUF2950) - - - 0.000000000000000000002938 94.0
PYH3_k127_6078370_18 Transposase IS200 like K07491 - - 0.0000000000000000001464 89.0
PYH3_k127_6078370_19 Transposase IS200 like K07491 - - 0.0000000000000000001971 88.0
PYH3_k127_6078370_2 MOFRL family K11529 - 2.7.1.165 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 601.0
PYH3_k127_6078370_20 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000003275 91.0
PYH3_k127_6078370_21 - - - - 0.000000000003408 72.0
PYH3_k127_6078370_22 DNA integration - - - 0.0000001815 53.0
PYH3_k127_6078370_3 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00042 - 1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 475.0
PYH3_k127_6078370_4 Belongs to the hyi family K01816 - 5.3.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 398.0
PYH3_k127_6078370_5 dienelactone hydrolase K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001345 365.0
PYH3_k127_6078370_6 Belongs to the TPP enzyme family K01608 - 4.1.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007423 342.0
PYH3_k127_6078370_7 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002563 319.0
PYH3_k127_6078370_8 Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 290.0
PYH3_k127_6078370_9 Putative metallopeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001217 261.0
PYH3_k127_6124393_0 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 314.0
PYH3_k127_6124393_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.0000000000000000000000000000000000000000000000000000000000000000324 231.0
PYH3_k127_6124393_2 Protein of unknown function (DUF3365) - - - 0.000000000000000000000000000000000000000000000001959 180.0
PYH3_k127_6124393_3 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000004056 168.0
PYH3_k127_6124393_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000004271 178.0
PYH3_k127_6124393_5 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000000000000000000000000001774 130.0
PYH3_k127_6124393_6 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000006489 108.0
PYH3_k127_6124393_7 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.0000000118 59.0
PYH3_k127_6165825_0 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008298 330.0
PYH3_k127_6165825_1 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000004114 173.0
PYH3_k127_6165825_2 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000001131 152.0
PYH3_k127_6165825_3 - - - - 0.0000000000000000000000000000000000000008944 158.0
PYH3_k127_6165825_4 Cas6 Crispr - - - 0.000000000000000000000000000000000000002172 157.0
PYH3_k127_6165825_5 - - - - 0.000000000000000000001394 97.0
PYH3_k127_6168519_0 Atp-dependent helicase K03578 - 3.6.4.13 0.0 1694.0
PYH3_k127_6168519_1 4Fe-4S ferredoxin, iron-sulfur binding K18929 - - 1.043e-223 703.0
PYH3_k127_6168519_10 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 347.0
PYH3_k127_6168519_11 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008639 349.0
PYH3_k127_6168519_12 PFAM molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003761 332.0
PYH3_k127_6168519_13 Belongs to the peptidase S11 family K07262 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002075 314.0
PYH3_k127_6168519_14 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001722 282.0
PYH3_k127_6168519_15 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000003958 244.0
PYH3_k127_6168519_16 PFAM thioesterase superfamily protein K07107 - - 0.0000000000000000000000000000000000000000000000000000000000005227 214.0
PYH3_k127_6168519_17 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000004968 205.0
PYH3_k127_6168519_18 protein conserved in bacteria K09790 - - 0.0000000000000000000000000000000000000174 149.0
PYH3_k127_6168519_19 TIGRFAM phasin family protein - - - 0.00000000000000000000000000000000001019 143.0
PYH3_k127_6168519_2 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 602.0
PYH3_k127_6168519_20 - - - - 0.0000000000000000000007265 104.0
PYH3_k127_6168519_21 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000007405 101.0
PYH3_k127_6168519_22 Bacteriophage replication gene A protein (GPA) - - - 0.0000000009505 67.0
PYH3_k127_6168519_3 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009944 462.0
PYH3_k127_6168519_4 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001918 422.0
PYH3_k127_6168519_5 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004675 393.0
PYH3_k127_6168519_6 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 397.0
PYH3_k127_6168519_7 Cysteine-rich domain K18928 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009796 382.0
PYH3_k127_6168519_8 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003163 381.0
PYH3_k127_6168519_9 histone deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001239 374.0
PYH3_k127_6195206_0 TIGRFAM Addiction module antidote protein, HigA K21498 - - 0.00000000000000000000000000000000000009164 147.0
PYH3_k127_6195206_1 Plasmid maintenance system killer K07334 - - 0.00000000000000000000000000000000009574 134.0
PYH3_k127_6195206_2 PIN domain - - - 0.000000000000000000001174 100.0
PYH3_k127_6195206_3 toxin-antitoxin pair type II binding - - - 0.0000000006747 63.0
PYH3_k127_6195206_4 PEP-CTERM motif - - - 0.0002999 44.0
PYH3_k127_6199174_0 denitrification pathway - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003793 276.0
PYH3_k127_6199174_1 formate dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003233 259.0
PYH3_k127_6199174_2 Cytochrome c - - - 0.0000000000000000000000000001334 129.0
PYH3_k127_6203155_0 Enoyl-CoA hydratase/isomerase K15513 - 4.1.2.44 5.923e-267 834.0
PYH3_k127_6203155_1 Benzoyl-CoA oxygenase K15512 - 1.14.13.208 1.122e-255 793.0
PYH3_k127_6203155_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 1.402e-239 750.0
PYH3_k127_6203155_3 Aldehyde dehydrogenase family K15514 - 1.2.1.77 3.538e-215 679.0
PYH3_k127_6203155_4 Oxidoreductase NAD-binding domain K15511 - 1.14.13.208 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005392 446.0
PYH3_k127_6203155_5 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 437.0
PYH3_k127_6203155_6 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003174 374.0
PYH3_k127_6203155_7 Domain of unknown function (DUF4863) - - - 0.000000000000000000000000000000000000000000000000000000000000000001372 229.0
PYH3_k127_6235618_0 Belongs to the GMC oxidoreductase family K00108 - 1.1.99.1 6.121e-277 863.0
PYH3_k127_6235618_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.353e-213 673.0
PYH3_k127_6235618_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002886 267.0
PYH3_k127_6235618_11 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006412 282.0
PYH3_k127_6235618_12 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001555 249.0
PYH3_k127_6235618_13 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.00000000000000000000000000000000000000000000000000000379 201.0
PYH3_k127_6235618_14 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.00000000000000000000000000000000000000000000000002169 185.0
PYH3_k127_6235618_15 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000005005 182.0
PYH3_k127_6235618_17 Post-segregation antitoxin CcdA K19164 - - 0.00000000000000000192 90.0
PYH3_k127_6235618_2 Dehydrogenase K15515 - 1.2.1.81 1.664e-208 657.0
PYH3_k127_6235618_3 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001025 583.0
PYH3_k127_6235618_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 508.0
PYH3_k127_6235618_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 494.0
PYH3_k127_6235618_6 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008691 464.0
PYH3_k127_6235618_7 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002386 394.0
PYH3_k127_6235618_8 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002109 380.0
PYH3_k127_6235618_9 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001491 316.0
PYH3_k127_6236800_0 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 587.0
PYH3_k127_6236800_1 Spermidine putrescine-binding periplasmic protein K02055 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 587.0
PYH3_k127_6236800_2 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004166 474.0
PYH3_k127_6236800_3 ABC-type spermidine putrescine transport system, permease component I K02054 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 449.0
PYH3_k127_6236800_4 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002098 365.0
PYH3_k127_6236800_5 - - - - 0.0000000000000000000000000000000000000002128 151.0
PYH3_k127_6253478_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1180.0
PYH3_k127_6253478_1 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000106 271.0
PYH3_k127_6262101_0 transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000009884 236.0
PYH3_k127_6262101_1 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000001512 147.0
PYH3_k127_6262101_2 PFAM amidohydrolase - - - 0.00000000000000000000000000000000002335 136.0
PYH3_k127_6262101_3 KTSC domain - - - 0.000000859 55.0
PYH3_k127_6281518_0 PFAM Integrase catalytic region - - - 6.089e-301 927.0
PYH3_k127_6281518_1 PFAM IstB domain protein ATP-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000585 442.0
PYH3_k127_6281518_2 coenzyme F420-1:gamma-L-glutamate ligase activity - - - 0.0000000000000000000000000000000000000000000000011 181.0
PYH3_k127_6281518_3 Protein of unknown function (DUF433) - - - 0.000000000000000000000000000000001797 132.0
PYH3_k127_6281518_4 N-6 DNA methylase K03427 - 2.1.1.72 0.00000000000000001443 82.0
PYH3_k127_6283608_0 PQQ enzyme repeat - - - 5.49e-211 658.0
PYH3_k127_6283608_1 TonB-dependent receptor K02014 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001891 297.0
PYH3_k127_6283608_2 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000001386 233.0
PYH3_k127_6291164_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1409.0
PYH3_k127_6291164_1 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.096e-303 937.0
PYH3_k127_6291164_10 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000445 263.0
PYH3_k127_6291164_11 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000002087 259.0
PYH3_k127_6291164_12 Phosphoglycolate phosphatase K22292 - 3.1.3.105 0.000000000000000000000000000000000000000000000000000000000000000000000001094 260.0
PYH3_k127_6291164_13 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000001529 229.0
PYH3_k127_6291164_14 AsmA family - - - 0.0000000000000000000000000000000000000000000000000000000000001204 236.0
PYH3_k127_6291164_15 - - - - 0.00000000000000000000000000000000000000000003499 176.0
PYH3_k127_6291164_16 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000607 160.0
PYH3_k127_6291164_17 Histidine kinase K20974 - 2.7.13.3 0.00000000000000000000002785 100.0
PYH3_k127_6291164_18 Histidine Phosphotransfer domain - - - 0.0000000000000000000001674 100.0
PYH3_k127_6291164_19 Helix-hairpin-helix motif K02237 - - 0.0000000000000000001716 96.0
PYH3_k127_6291164_2 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 519.0
PYH3_k127_6291164_20 Lipopolysaccharide assembly protein A domain K08992 - - 0.00003851 51.0
PYH3_k127_6291164_3 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 511.0
PYH3_k127_6291164_4 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 GO:0000003,GO:0000096,GO:0000097,GO:0000902,GO:0000904,GO:0003006,GO:0003674,GO:0003824,GO:0004124,GO:0005488,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0005773,GO:0005774,GO:0005777,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006534,GO:0006535,GO:0006563,GO:0006790,GO:0006807,GO:0007568,GO:0008144,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009507,GO:0009532,GO:0009536,GO:0009566,GO:0009567,GO:0009570,GO:0009653,GO:0009826,GO:0009856,GO:0009860,GO:0009932,GO:0009987,GO:0010035,GO:0010038,GO:0016020,GO:0016043,GO:0016049,GO:0016053,GO:0016740,GO:0016765,GO:0019344,GO:0019752,GO:0019842,GO:0019953,GO:0022414,GO:0030154,GO:0030170,GO:0031090,GO:0032501,GO:0032502,GO:0032989,GO:0036094,GO:0040007,GO:0042221,GO:0042579,GO:0043167,GO:0043168,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044706,GO:0046394,GO:0046686,GO:0048037,GO:0048046,GO:0048468,GO:0048588,GO:0048589,GO:0048856,GO:0048868,GO:0048869,GO:0050662,GO:0050896,GO:0051704,GO:0060560,GO:0070279,GO:0071704,GO:0071840,GO:0071944,GO:0097159,GO:0098588,GO:0098805,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 490.0
PYH3_k127_6291164_5 beta' subunit K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001634 483.0
PYH3_k127_6291164_6 TIGRFAM chorismate mutase domain of proteobacterial P-protein, clade 2 K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004618 475.0
PYH3_k127_6291164_7 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 473.0
PYH3_k127_6291164_8 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001337 372.0
PYH3_k127_6291164_9 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002425 342.0
PYH3_k127_6302156_0 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001834 502.0
PYH3_k127_6302156_1 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003566 243.0
PYH3_k127_6302156_2 Transport of potassium into the cell K03549 - - 0.000000000000000000000000000000000000000000000000000000000000002449 220.0
PYH3_k127_6302156_3 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K17837 - 3.5.2.6 0.0000000000000000000000000002061 126.0
PYH3_k127_6304264_0 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000001345 177.0
PYH3_k127_6304264_1 cyclic nucleotide binding K10914 - - 0.00000000000000000000000000002103 123.0
PYH3_k127_6304264_3 chaperone-mediated protein folding - - - 0.00000000001525 76.0
PYH3_k127_6315742_0 Belongs to the TPP enzyme family K01608 - 4.1.1.47 1.335e-251 780.0
PYH3_k127_6315742_1 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 476.0
PYH3_k127_6315742_2 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005252 383.0
PYH3_k127_6315742_3 - - - - 0.000000000000121 76.0
PYH3_k127_6364982_0 AAA domain K07133 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000566 398.0
PYH3_k127_6364982_1 Transcriptional regulator - - - 0.000000000000000000000000000000495 126.0
PYH3_k127_6364982_2 Domain of unknown function (DUF4387) - - - 0.000000000000000000001826 98.0
PYH3_k127_6364982_3 - - - - 0.000000000000000001108 86.0
PYH3_k127_6364982_4 Plasmid stability protein K21495 - - 0.00000000000000001606 87.0
PYH3_k127_6364982_5 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000001709 61.0
PYH3_k127_6365445_0 Participates in both transcription termination and antitermination K02600 - - 5.116e-212 669.0
PYH3_k127_6365445_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007151 470.0
PYH3_k127_6365445_2 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 364.0
PYH3_k127_6365445_3 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 284.0
PYH3_k127_6365445_4 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 GO:0000976,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006282,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009432,GO:0009605,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0009991,GO:0010467,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016070,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031668,GO:0032774,GO:0032991,GO:0032993,GO:0033554,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0043170,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0045892,GO:0045934,GO:0046483,GO:0048519,GO:0048523,GO:0048583,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051716,GO:0060255,GO:0065007,GO:0071496,GO:0071704,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2001020,GO:2001141 3.4.21.88 0.00000000000000000000000000000000000000000000000000000000000000000000001559 248.0
PYH3_k127_6365445_5 Required for maturation of 30S ribosomal subunits K09748 - - 0.000000000000000000000000000000000000000000103 171.0
PYH3_k127_6365445_6 PFAM PIN domain - - - 0.000000000002485 68.0
PYH3_k127_6365445_7 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.0000001777 56.0
PYH3_k127_6367749_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 1.302e-304 938.0
PYH3_k127_6367749_1 PrkA AAA domain K07180 - - 8.929e-275 859.0
PYH3_k127_6367749_10 Ppx/GppA phosphatase family K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 463.0
PYH3_k127_6367749_11 RNA polymerase sigma factor RpoH K03089 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001872 425.0
PYH3_k127_6367749_12 cytochrome oxidase assembly K02259 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 426.0
PYH3_k127_6367749_13 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007191 422.0
PYH3_k127_6367749_14 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006927 414.0
PYH3_k127_6367749_15 Protein of unknown function (DUF2868) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 422.0
PYH3_k127_6367749_16 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008175 404.0
PYH3_k127_6367749_17 Belongs to the UPF0229 family K09786 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 407.0
PYH3_k127_6367749_18 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 388.0
PYH3_k127_6367749_19 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 402.0
PYH3_k127_6367749_2 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 1.716e-256 810.0
PYH3_k127_6367749_20 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003644 351.0
PYH3_k127_6367749_21 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001284 343.0
PYH3_k127_6367749_22 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 299.0
PYH3_k127_6367749_23 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007028 284.0
PYH3_k127_6367749_24 MOSC N-terminal beta barrel domain K07140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003592 276.0
PYH3_k127_6367749_25 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003806 265.0
PYH3_k127_6367749_26 PFAM regulatory protein TetR K05501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009198 262.0
PYH3_k127_6367749_27 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001886 272.0
PYH3_k127_6367749_28 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.000000000000000000000000000000000000000000000000000000000000000000000001788 248.0
PYH3_k127_6367749_29 cytochrome C oxidase K02258 - - 0.00000000000000000000000000000000000000000000000000000000000000000000005488 244.0
PYH3_k127_6367749_3 Peptidase family S49 K04773 - - 7.421e-216 687.0
PYH3_k127_6367749_30 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000008356 250.0
PYH3_k127_6367749_31 Hydrolase K07025 - - 0.000000000000000000000000000000000000000000000000000000000000000521 228.0
PYH3_k127_6367749_32 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000001489 225.0
PYH3_k127_6367749_33 response to antibiotic - - - 0.000000000000000000000000000000000000000000000000000000000000004511 229.0
PYH3_k127_6367749_34 signal sequence binding - - - 0.0000000000000000000000000000000000000000000000000000000000000423 219.0
PYH3_k127_6367749_35 Protein of unknown function (DUF418) K07148 - - 0.000000000000000000000000000000000000000000000000000000000005632 224.0
PYH3_k127_6367749_36 Lysin motif - - - 0.00000000000000000000000000000000000000000000000000000001354 203.0
PYH3_k127_6367749_37 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.00000000000000000000000000000000000000000000000000001276 194.0
PYH3_k127_6367749_38 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000009014 190.0
PYH3_k127_6367749_39 Methyltransferase K08316 - 2.1.1.171 0.0000000000000000000000000000000000000000000000001568 196.0
PYH3_k127_6367749_4 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 2.806e-211 665.0
PYH3_k127_6367749_40 phosphohistidine phosphatase K08296 - - 0.000000000000000000000000000000000000000000000007444 175.0
PYH3_k127_6367749_41 SURF1-like protein K14998 - - 0.0000000000000000000000000000000000000000000002174 178.0
PYH3_k127_6367749_42 Type II secretory pathway, component - - - 0.00000000000000000000000000000000000000000108 167.0
PYH3_k127_6367749_43 PFAM Phosphoribosyltransferase - - - 0.00000000000000000000000000000000000000004252 167.0
PYH3_k127_6367749_44 Copper chaperone PCu(A)C K09796 - - 0.0000000000000000000000000000000000000009081 152.0
PYH3_k127_6367749_45 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.000000000000000000000000000000000001404 140.0
PYH3_k127_6367749_46 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000002025 136.0
PYH3_k127_6367749_47 PFAM Rhodanese domain protein K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000007155 134.0
PYH3_k127_6367749_48 Integral membrane protein (DUF2244) - - - 0.0000000000000000000000001775 111.0
PYH3_k127_6367749_49 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000000000008934 97.0
PYH3_k127_6367749_5 Domain of unknown function (DUF3482) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006851 561.0
PYH3_k127_6367749_50 Protein of unknown function (DUF2970) - - - 0.000000000000000001085 91.0
PYH3_k127_6367749_51 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000003772 68.0
PYH3_k127_6367749_52 mercury ion transmembrane transporter activity - - - 0.0000000008497 64.0
PYH3_k127_6367749_54 - - - - 0.0002845 51.0
PYH3_k127_6367749_6 SpoVR family K06415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000272 556.0
PYH3_k127_6367749_7 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 547.0
PYH3_k127_6367749_8 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000452 518.0
PYH3_k127_6367749_9 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005326 477.0
PYH3_k127_6376914_0 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 4.34e-280 865.0
PYH3_k127_6376914_1 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K01086,K03841 - 3.1.3.11,3.1.3.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007347 525.0
PYH3_k127_6376914_2 ATPase family associated with various cellular activities (AAA) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003725 445.0
PYH3_k127_6376914_3 PFAM ribulose bisphosphate carboxylase small chain K01602 - 4.1.1.39 0.00000000000000000000000000000000000000000000000000000000000005027 226.0
PYH3_k127_6380669_0 PFAM Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002138 286.0
PYH3_k127_6380669_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002229 281.0
PYH3_k127_6380669_10 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000003387 134.0
PYH3_k127_6380669_11 ParE toxin of type II toxin-antitoxin system, parDE - - - 0.000000000000000000000000000000004232 130.0
PYH3_k127_6380669_12 Transcriptional regulator - - - 0.0000000000000000000000000000009303 125.0
PYH3_k127_6380669_13 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.00000000000000000000000000002857 124.0
PYH3_k127_6380669_14 Beta-lactamase - - - 0.000000000000000000000000000175 122.0
PYH3_k127_6380669_15 - - - - 0.000000000000000003948 85.0
PYH3_k127_6380669_16 Transcriptional regulator - - - 0.000000000000277 69.0
PYH3_k127_6380669_17 peptidase - - - 0.000000000007652 66.0
PYH3_k127_6380669_18 .,Oxidizes proline to glutamate for use as a carbon and nitrogen source - - - 0.0000000002467 64.0
PYH3_k127_6380669_19 peptidase - - - 0.00000009073 61.0
PYH3_k127_6380669_2 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001312 276.0
PYH3_k127_6380669_3 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000778 261.0
PYH3_k127_6380669_4 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000003909 183.0
PYH3_k127_6380669_5 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000007369 180.0
PYH3_k127_6380669_6 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000001048 172.0
PYH3_k127_6380669_7 Glyoxalase-like domain - - - 0.00000000000000000000000000000000000000000001116 172.0
PYH3_k127_6380669_8 Addiction module toxin, RelE StbE family K07334 - - 0.000000000000000000000000000000000001255 139.0
PYH3_k127_6380669_9 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.000000000000000000000000000000000001292 143.0
PYH3_k127_6382040_0 Protein of unknown function (DUF2867) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002321 274.0
PYH3_k127_6403923_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.000000000000000000000000000000000000000000000000000000000000000005456 233.0
PYH3_k127_6403923_1 PFAM Cytochrome c, class I K08738 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.00000000004698 65.0
PYH3_k127_640408_0 amidohydrolase K01451 - 3.5.1.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001268 564.0
PYH3_k127_640408_1 AAA domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 396.0
PYH3_k127_6404271_0 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 1.221e-241 768.0
PYH3_k127_6404271_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 4.788e-228 727.0
PYH3_k127_6404271_10 Acyltransferase K00655 - 2.3.1.51 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 292.0
PYH3_k127_6404271_11 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002301 287.0
PYH3_k127_6404271_12 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003914 279.0
PYH3_k127_6404271_13 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002132 262.0
PYH3_k127_6404271_14 Nucleotidyl transferase K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000001009 239.0
PYH3_k127_6404271_15 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000000000000000000000000000000002579 229.0
PYH3_k127_6404271_16 Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000003572 213.0
PYH3_k127_6404271_17 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.000000000000000000000000000000000000000000000000000001365 197.0
PYH3_k127_6404271_18 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000388 157.0
PYH3_k127_6404271_19 Belongs to the transcriptional regulatory Fis family K03557 - - 0.0000000000000000000007736 98.0
PYH3_k127_6404271_2 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001053 617.0
PYH3_k127_6404271_20 - - - - 0.000000000000000002451 89.0
PYH3_k127_6404271_21 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB K03559 - - 0.00000001269 56.0
PYH3_k127_6404271_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009165 538.0
PYH3_k127_6404271_4 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004642 497.0
PYH3_k127_6404271_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003296 468.0
PYH3_k127_6404271_6 Aminoglycoside phosphotransferase K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000335 461.0
PYH3_k127_6404271_7 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003625 458.0
PYH3_k127_6404271_8 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008278 370.0
PYH3_k127_6404271_9 MotA/TolQ/ExbB proton channel family K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002132 360.0
PYH3_k127_6412264_0 Belongs to the glycosyl hydrolase family 6 - - - 9.946e-240 760.0
PYH3_k127_6412264_1 Transposase DDE domain - - - 6.576e-222 705.0
PYH3_k127_6412264_2 transposase and inactivated derivatives, IS30 family - - - 0.000000000000002508 77.0
PYH3_k127_6412264_3 transposase and inactivated derivatives, IS30 family - - - 0.00000000001192 70.0
PYH3_k127_6423217_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 599.0
PYH3_k127_6423217_1 FAD dependent oxidoreductase K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002136 464.0
PYH3_k127_6423887_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 2.694e-214 670.0
PYH3_k127_6423887_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 592.0
PYH3_k127_6423887_2 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000003212 109.0
PYH3_k127_6449356_0 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 8.96e-242 762.0
PYH3_k127_6449356_1 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000004262 210.0
PYH3_k127_6449356_2 PA domain - - - 0.00000000000000000000000000000000005057 136.0
PYH3_k127_6449356_3 PA domain - - - 0.0000000000001278 78.0
PYH3_k127_6449356_4 COG3328 Transposase and inactivated derivatives - - - 0.00001045 51.0
PYH3_k127_6452000_0 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 542.0
PYH3_k127_6452000_1 beta-lactamase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006029 331.0
PYH3_k127_6452000_2 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000000000000000000000000000000000000000005039 216.0
PYH3_k127_6452000_4 regulatory - - - 0.000000000000000000000000000000000000000000000000001463 190.0
PYH3_k127_6452000_5 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.000000000000000000000000000000000000000000002978 179.0
PYH3_k127_6452000_6 PFAM MaoC domain protein dehydratase - - - 0.00000000000000000000000000000000000000001977 158.0
PYH3_k127_6452000_7 Protein of unknown function (DUF3455) - - - 0.000000000000000000000000001648 119.0
PYH3_k127_6452000_8 PFAM MaoC domain protein dehydratase - - - 0.000000000000000428 80.0
PYH3_k127_6452000_9 - - - - 0.00000000002905 70.0
PYH3_k127_6465602_0 AMP-binding enzyme K12508 - 6.2.1.34 3.378e-241 758.0
PYH3_k127_6465602_1 2-oxoacid ferredoxin oxidoreductase, alpha subunit K00169,K19070 GO:0003674,GO:0003824,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:1901575 1.2.7.1,1.2.7.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000226 515.0
PYH3_k127_6465602_2 HI0933-like protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 512.0
PYH3_k127_6465602_3 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 471.0
PYH3_k127_6465602_4 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008242 401.0
PYH3_k127_6465602_5 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003074 321.0
PYH3_k127_6465602_6 oxidoreductase gamma subunit K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000001046 183.0
PYH3_k127_6473767_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 4.148e-225 707.0
PYH3_k127_6473767_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 1.011e-214 676.0
PYH3_k127_6473767_2 Actin K03569 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 521.0
PYH3_k127_6473767_3 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000012 121.0
PYH3_k127_6473767_4 Domain of unknown function (DUF4382) - - - 0.00000008369 57.0
PYH3_k127_6522049_0 NMT1-like family K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 527.0
PYH3_k127_6522049_1 ABC transporter K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 457.0
PYH3_k127_6522049_2 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K15509 - 1.1.1.308 0.00000000000000000000000000000000000000000000000000000000000000002697 226.0
PYH3_k127_6532653_0 PFAM Orn Lys Arg decarboxylase K01584 - 4.1.1.19 0.0 1098.0
PYH3_k127_6532653_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035,K12368 - - 1.346e-293 910.0
PYH3_k127_6532653_2 Belongs to the peptidase S16 family - - - 5.217e-280 881.0
PYH3_k127_6532653_3 PFAM binding-protein-dependent transport systems inner membrane component K02033,K12369 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 559.0
PYH3_k127_6532653_4 Belongs to the ABC transporter superfamily K12372 GO:0000166,GO:0003674,GO:0005215,GO:0005488,GO:0005524,GO:0006810,GO:0008144,GO:0008150,GO:0009314,GO:0009628,GO:0015232,GO:0015886,GO:0017076,GO:0022857,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0050896,GO:0051179,GO:0051181,GO:0051184,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901678 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009263 490.0
PYH3_k127_6532653_5 TIGRFAM deoxycytidine triphosphate deaminase K01494 - 3.5.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001531 493.0
PYH3_k127_6532653_6 Belongs to the ABC transporter superfamily K02031,K12371 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 493.0
PYH3_k127_6532653_7 PFAM binding-protein-dependent transport systems inner membrane component K02034,K12370 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 457.0
PYH3_k127_6532653_8 AMP binding - - - 0.0000608 53.0
PYH3_k127_6539282_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001497 296.0
PYH3_k127_6539282_1 COG1961 Site-specific recombinases, DNA invertase Pin homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000002175 250.0
PYH3_k127_6539282_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000001131 220.0
PYH3_k127_6539282_3 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000001474 212.0
PYH3_k127_6539282_5 - - - - 0.000000000000000003649 84.0
PYH3_k127_6539282_6 - - - - 0.000000000001575 72.0
PYH3_k127_6543958_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 0.0 1741.0
PYH3_k127_6543958_1 Uncharacterized ACR, YdiU/UPF0061 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 384.0
PYH3_k127_6543958_2 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 306.0
PYH3_k127_6543958_3 PFAM Metal-dependent hydrolase HDOD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 297.0
PYH3_k127_6543958_4 PPIC-type PPIASE domain K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002721 279.0
PYH3_k127_6543958_5 probably involved in intracellular septation K06190 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002262 247.0
PYH3_k127_6543958_6 5-oxoprolinase K01469 - 3.5.2.9 0.000000000000000000000000000000000000000000000000000006284 190.0
PYH3_k127_6543958_7 - - - - 0.000000000000000000000000000003694 126.0
PYH3_k127_6543958_8 Belongs to the BolA IbaG family K05527 - - 0.000000000000000000000000049 110.0
PYH3_k127_6549819_0 helicase superfamily c-terminal domain K03724 - - 0.0 1072.0
PYH3_k127_6549819_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1028.0
PYH3_k127_6549819_10 PhoD-like phosphatase K01113 - 3.1.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 447.0
PYH3_k127_6549819_11 Pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008654 437.0
PYH3_k127_6549819_12 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 419.0
PYH3_k127_6549819_13 Endonuclease/Exonuclease/phosphatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003609 382.0
PYH3_k127_6549819_14 Belongs to the ribose-phosphate pyrophosphokinase family K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009656 324.0
PYH3_k127_6549819_15 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007059 301.0
PYH3_k127_6549819_16 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000001545 246.0
PYH3_k127_6549819_17 Nudix hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000000000004969 188.0
PYH3_k127_6549819_18 PFAM HNH endonuclease - - - 0.0000000000000000000000000000000000000000000000002686 183.0
PYH3_k127_6549819_19 Activator of Hsp90 ATPase homolog 1-like protein - - - 0.00000000000000000000000000000000000000000000007439 174.0
PYH3_k127_6549819_2 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 6.1e-322 992.0
PYH3_k127_6549819_20 aminopeptidase N - - - 0.0000000000000000000000000000000000004697 158.0
PYH3_k127_6549819_21 Protein of unknown function (DUF1272) K09984 - - 0.000000000000000000000000000000000003461 139.0
PYH3_k127_6549819_22 SWIB/MDM2 domain K03169 - 5.99.1.2 0.0000000000000000000000000000000001134 138.0
PYH3_k127_6549819_23 Regulatory protein, FmdB family - - - 0.00000000000000000000000000002969 122.0
PYH3_k127_6549819_24 - - - - 0.0000000000000000000000000002965 116.0
PYH3_k127_6549819_25 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.000000000000000000000000001342 118.0
PYH3_k127_6549819_26 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000009441 101.0
PYH3_k127_6549819_27 Acetyltransferase (GNAT) domain - - - 0.000000000000000004994 91.0
PYH3_k127_6549819_28 PFAM CBS domain containing protein - - - 0.000000000000001681 90.0
PYH3_k127_6549819_29 PFAM Copper binding periplasmic protein CusF - - - 0.000000000001224 72.0
PYH3_k127_6549819_3 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 2.247e-236 747.0
PYH3_k127_6549819_30 PEP-CTERM motif - - - 0.0001153 52.0
PYH3_k127_6549819_4 The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis K00758 - 2.4.2.4 2.96e-231 728.0
PYH3_k127_6549819_5 B12 binding domain - - - 1.016e-204 652.0
PYH3_k127_6549819_6 Fructose-1,6-bisphosphatase K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004968 550.0
PYH3_k127_6549819_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 498.0
PYH3_k127_6549819_8 Multicopper oxidase K04753,K08100 - 1.3.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 496.0
PYH3_k127_6549819_9 Beta-Casp domain K07576 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 445.0
PYH3_k127_6555295_0 Elongation factor SelB, winged helix K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007762 581.0
PYH3_k127_6555295_1 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008333 502.0
PYH3_k127_6555295_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 436.0
PYH3_k127_6555295_3 Necessary for formate dehydrogenase activity K02380 - - 0.00000000000000000000000000000000000000000000000000000000000000000000006738 250.0
PYH3_k127_6555295_4 Prokaryotic cytochrome b561 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004669 231.0
PYH3_k127_6555295_5 Glycine cleavage H-protein - - - 0.0000000000000000000000001716 112.0
PYH3_k127_6555295_6 DsrE/DsrF-like family - - - 0.0000000000000003111 83.0
PYH3_k127_6555295_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000001172 59.0
PYH3_k127_6555295_8 Translation elongation factor K03833 GO:0000049,GO:0000166,GO:0001514,GO:0001882,GO:0001883,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006412,GO:0006414,GO:0006417,GO:0006451,GO:0006518,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009069,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010608,GO:0016259,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0019003,GO:0019222,GO:0019538,GO:0019752,GO:0031323,GO:0031326,GO:0032268,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034248,GO:0034641,GO:0034645,GO:0035368,GO:0035639,GO:0036094,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0051171,GO:0051246,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:2000112 - 0.000003785 59.0
PYH3_k127_6559214_0 COG4664 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 459.0
PYH3_k127_6559214_1 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000001379 149.0
PYH3_k127_6559214_2 COG4663 TRAP-type mannitol chloroaromatic compound transport system, periplasmic component - - - 0.0000000000000000000000000000002053 128.0
PYH3_k127_6559214_3 FAD dependent oxidoreductase - - - 0.000000000000003585 75.0
PYH3_k127_6559214_4 succinate dehydrogenase - - - 0.0002039 47.0
PYH3_k127_6573699_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004255 481.0
PYH3_k127_6573699_1 Histidine kinase K20976 - - 0.0000000000000000000000006911 108.0
PYH3_k127_6573699_2 Histidine kinase-like ATPases K01768,K02488,K17763 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0042802,GO:0044424,GO:0044464 2.7.7.65,4.6.1.1 0.000000213 53.0
PYH3_k127_6583044_0 3-hydroxyacyl-CoA dehydrogenase NAD-binding K07516 - 1.1.1.35 6.594e-275 863.0
PYH3_k127_6583044_1 acyl-CoA dehydrogenase K00248 - 1.3.8.1 6.818e-246 773.0
PYH3_k127_6583044_2 viral genome integration into host DNA - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 430.0
PYH3_k127_6583044_3 Involved in the nonphosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 395.0
PYH3_k127_6583044_4 Alpha beta hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005393 340.0
PYH3_k127_6583044_5 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008314 337.0
PYH3_k127_6583044_6 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000007771 225.0
PYH3_k127_6583044_7 cyclic nucleotide-binding - - - 0.0000000000000000000000000000000003945 140.0
PYH3_k127_6583044_8 PFAM thioesterase superfamily protein - - - 0.0000000000000000000000000000000009349 136.0
PYH3_k127_6583044_9 Tetratricopeptide repeat - - - 0.00008175 54.0
PYH3_k127_6596547_0 COG0823 Periplasmic component of the Tol biopolymer transport system - - - 0.0 1457.0
PYH3_k127_6596547_1 Tetratricopeptide repeat - - - 2.15e-234 742.0
PYH3_k127_6596547_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001314 277.0
PYH3_k127_6596547_11 Belongs to the WrbA family K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006173 278.0
PYH3_k127_6596547_12 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003181 273.0
PYH3_k127_6596547_13 Glutathione peroxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000531 257.0
PYH3_k127_6596547_14 Predicted membrane protein (DUF2069) - - - 0.00000000000000000000000000004675 124.0
PYH3_k127_6596547_15 Domain of unknown function (DUF4124) - - - 0.0002306 49.0
PYH3_k127_6596547_2 Tetratricopeptide repeat - - - 5.505e-217 691.0
PYH3_k127_6596547_3 COG0277 FAD FMN-containing dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002426 542.0
PYH3_k127_6596547_4 Protein of unknown function (DUF3570) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002883 496.0
PYH3_k127_6596547_5 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005722 424.0
PYH3_k127_6596547_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 426.0
PYH3_k127_6596547_7 Bacterial SH3 domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 355.0
PYH3_k127_6596547_8 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 290.0
PYH3_k127_6596547_9 UPF0761 membrane protein K07058 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003352 297.0
PYH3_k127_6647488_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin - - - 0.0 1557.0
PYH3_k127_6647488_1 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.0 1283.0
PYH3_k127_6647488_10 CitB domain protein K13795 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001418 610.0
PYH3_k127_6647488_11 Arsenical pump membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000166 590.0
PYH3_k127_6647488_12 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. The first step is catalyzed by NqrF, which accepts electrons from NADH and reduces ubiquinone-1 to ubisemiquinone by a one-electron transfer pathway K00351 - 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008534 578.0
PYH3_k127_6647488_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001561 559.0
PYH3_k127_6647488_14 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00346 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0015672,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0030964,GO:0032991,GO:0044425,GO:0050136,GO:0051179,GO:0051234,GO:0055114,GO:0098796,GO:1902494 1.6.5.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 503.0
PYH3_k127_6647488_15 TRAP dicarboxylate transporter, DctP subunit K11688 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 492.0
PYH3_k127_6647488_16 NADH-quinone oxidoreductase, chain M K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006712 498.0
PYH3_k127_6647488_17 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009838 495.0
PYH3_k127_6647488_18 RIO1 family K07178 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004935 481.0
PYH3_k127_6647488_19 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002272 472.0
PYH3_k127_6647488_2 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239,K00244 - 1.3.5.1,1.3.5.4 0.0 1030.0
PYH3_k127_6647488_20 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 463.0
PYH3_k127_6647488_21 Oxidoreductase family, C-terminal alpha/beta domain K00010,K18067 - 1.1.1.18,1.1.1.369,1.3.1.64 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007302 436.0
PYH3_k127_6647488_22 2Fe-2S iron-sulfur cluster binding domain K00245 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008085 385.0
PYH3_k127_6647488_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 394.0
PYH3_k127_6647488_24 NmrA-like family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003458 366.0
PYH3_k127_6647488_25 dihydroorotate dehydrogenase activity K00226 - 1.3.98.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002582 364.0
PYH3_k127_6647488_26 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00246 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 320.0
PYH3_k127_6647488_27 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
PYH3_k127_6647488_28 Tripartite ATP-independent periplasmic transporters, DctQ component K11689 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004409 299.0
PYH3_k127_6647488_29 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 296.0
PYH3_k127_6647488_3 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 1.738e-258 815.0
PYH3_k127_6647488_30 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 291.0
PYH3_k127_6647488_31 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00350 - 1.6.5.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001317 279.0
PYH3_k127_6647488_32 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00349 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015672,GO:0015980,GO:0016020,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0030001,GO:0030964,GO:0032991,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0044425,GO:0044464,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0051179,GO:0051234,GO:0055086,GO:0055114,GO:0071704,GO:0071944,GO:0072521,GO:0098796,GO:1901135,GO:1901360,GO:1901564,GO:1902494 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004525 277.0
PYH3_k127_6647488_33 Tetracyclin repressor, C-terminal all-alpha domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001346 269.0
PYH3_k127_6647488_34 iron ion binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001958 261.0
PYH3_k127_6647488_35 Transporter associated domain K03699 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000265 246.0
PYH3_k127_6647488_36 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000001126 258.0
PYH3_k127_6647488_37 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001725 249.0
PYH3_k127_6647488_38 NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol K00348 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006810,GO:0006811,GO:0006812,GO:0006814,GO:0008150,GO:0008152,GO:0010181,GO:0015672,GO:0016491,GO:0016651,GO:0016655,GO:0030001,GO:0032553,GO:0036094,GO:0043167,GO:0043168,GO:0048037,GO:0050662,GO:0051179,GO:0051234,GO:0055114,GO:0097159,GO:0097367,GO:1901265,GO:1901363 1.6.5.8 0.000000000000000000000000000000000000000000000000000000000000000005157 234.0
PYH3_k127_6647488_39 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 GO:0003674,GO:0003824,GO:0003954,GO:0006091,GO:0006119,GO:0006120,GO:0006139,GO:0006163,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008137,GO:0008150,GO:0008152,GO:0009117,GO:0009123,GO:0009126,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009167,GO:0009199,GO:0009205,GO:0009259,GO:0009987,GO:0015980,GO:0016310,GO:0016491,GO:0016651,GO:0016655,GO:0017144,GO:0019637,GO:0019693,GO:0022900,GO:0022904,GO:0034641,GO:0042773,GO:0042775,GO:0044237,GO:0044238,GO:0044281,GO:0045333,GO:0046034,GO:0046483,GO:0050136,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000004421 224.0
PYH3_k127_6647488_4 FAD dependent oxidoreductase K13796 - - 5.943e-236 736.0
PYH3_k127_6647488_40 TIGRFAM NADH-quinone oxidoreductase, E subunit K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000004096 240.0
PYH3_k127_6647488_41 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000006204 183.0
PYH3_k127_6647488_42 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00330 - 1.6.5.3 0.00000000000000000000000000000000000000000000007442 171.0
PYH3_k127_6647488_43 - - - - 0.00000000000000000000000000000000000000000002251 172.0
PYH3_k127_6647488_44 Lecithin retinol acyltransferase - - - 0.0000000000000000000000000000000000000002279 158.0
PYH3_k127_6647488_45 Cyclase dehydrase - - - 0.000000000000000000000000000000000000002239 159.0
PYH3_k127_6647488_46 Ferredoxin K05337 - - 0.0000000000000000000000000000000004418 133.0
PYH3_k127_6647488_47 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000003703 122.0
PYH3_k127_6647488_48 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000023 115.0
PYH3_k127_6647488_49 methylmalonate-semialdehyde dehydrogenase K00140 - 1.2.1.18,1.2.1.27 0.0000000000000000000001079 97.0
PYH3_k127_6647488_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.261e-229 715.0
PYH3_k127_6647488_50 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000007732 102.0
PYH3_k127_6647488_6 TRAP dicarboxylate transporter, DctM subunit K11690 - - 3.936e-222 696.0
PYH3_k127_6647488_7 Sodium:sulfate symporter transmembrane region K11106,K14445 - - 2.921e-218 689.0
PYH3_k127_6647488_8 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 1.931e-208 655.0
PYH3_k127_6647488_9 NADH-ubiquinone oxidoreductase-G iron-sulfur binding region K00336 - 1.6.5.3 8.557e-197 626.0
PYH3_k127_66904_0 Extracellular solute-binding protein, family 5 middle family protein 22 - - - 2.546e-269 850.0
PYH3_k127_66904_1 Involved in the tonB-independent uptake of proteins K03641 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005609 512.0
PYH3_k127_66904_10 Pterin binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 336.0
PYH3_k127_66904_11 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004781 320.0
PYH3_k127_66904_12 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001466 305.0
PYH3_k127_66904_13 P-loop containing region of AAA domain K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004214 312.0
PYH3_k127_66904_14 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005881 287.0
PYH3_k127_66904_15 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.00000000000000000000000000000000000000000000000000000000001776 215.0
PYH3_k127_66904_16 B12 binding domain - - - 0.000000000000000000000000000000000000000000000000000005079 197.0
PYH3_k127_66904_17 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000000003744 189.0
PYH3_k127_66904_18 system-associated acyl-CoA thioesterase K07107 - - 0.0000000000000000000000000000000000000005919 153.0
PYH3_k127_66904_19 Protein of unknown function (DUF1638) - - - 0.000000000000000000000000000000000000008521 155.0
PYH3_k127_66904_2 Sulphur transport K07112 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 467.0
PYH3_k127_66904_20 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000000000000000000000000000000000001532 157.0
PYH3_k127_66904_21 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000001736 143.0
PYH3_k127_66904_22 PFAM Tol-Pal system TolA K03646 - - 0.00000000000000000000000008166 123.0
PYH3_k127_66904_3 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 447.0
PYH3_k127_66904_4 PFAM amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002885 436.0
PYH3_k127_66904_5 dioxygenase activity K00477 - 1.14.11.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002537 396.0
PYH3_k127_66904_6 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003762 394.0
PYH3_k127_66904_7 PFAM 2Fe-2S iron-sulfur cluster binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003123 372.0
PYH3_k127_66904_8 hydrolase (HAD superfamily) K01560 - 3.8.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008098 341.0
PYH3_k127_66904_9 Binding-protein-dependent transport system inner membrane component K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007338 356.0
PYH3_k127_676266_0 Sarcosine oxidase, subunit beta K00303 - 1.5.3.1 1.043e-199 629.0
PYH3_k127_676266_1 Binding-protein-dependent transport system inner membrane component K02029 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001515 343.0
PYH3_k127_676266_2 Bacterial periplasmic substrate-binding proteins K02030 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 301.0
PYH3_k127_676266_3 Belongs to the GcvT family K00302 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 1.5.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 295.0
PYH3_k127_676266_4 PFAM ABC transporter related K02028,K09972,K10004 - 3.6.3.21 0.00000000000000000000000000000000000000000000000000000000000000000000155 246.0
PYH3_k127_676266_5 Aminoacyl-tRNA editing domain K19055 - - 0.000000000000000000000000000000000000000000000000000000000000007108 232.0
PYH3_k127_676266_6 Sarcosine oxidase, delta subunit family K22085 - 1.5.99.5 0.000000000000000000000000001465 117.0
PYH3_k127_676266_7 ABC transporter K02029,K10009 - - 0.0000000000000000000000009131 113.0
PYH3_k127_6771932_0 K+ potassium transporter K03549 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 581.0
PYH3_k127_6771932_1 nucleoside-diphosphate sugar epimerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 487.0
PYH3_k127_6773398_0 4Fe-4S dicluster domain K18930 - - 0.0 1144.0
PYH3_k127_6773398_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0 1059.0
PYH3_k127_6773398_10 abc transporter K02003,K05685 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005631 312.0
PYH3_k127_6773398_11 PFAM GGDEF domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009216 319.0
PYH3_k127_6773398_12 serine-type endopeptidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007623 274.0
PYH3_k127_6773398_13 Protein of unknown function, DUF480 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 264.0
PYH3_k127_6773398_14 Appr-1'-p processing enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000008967 214.0
PYH3_k127_6773398_15 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.000000000000000000000000000000000000000000000000000000002086 205.0
PYH3_k127_6773398_16 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.0000000000000000000000000000000000000000000000000002579 186.0
PYH3_k127_6773398_17 PIN domain - - - 0.00000000000000000000000000000000000000000009692 162.0
PYH3_k127_6773398_18 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000000000002446 118.0
PYH3_k127_6773398_19 Histidine kinase - - - 0.0000000000000000000000003699 113.0
PYH3_k127_6773398_2 GGDEF domain - - - 1.449e-311 976.0
PYH3_k127_6773398_20 - - - - 0.0000000000000000000000161 108.0
PYH3_k127_6773398_21 - - - - 0.00000000000000000236 89.0
PYH3_k127_6773398_22 mRNA binding K07339 - - 0.00000000000000002099 81.0
PYH3_k127_6773398_23 positive regulation of growth - - - 0.00000000000002105 75.0
PYH3_k127_6773398_3 GGDEF domain - - - 7.963e-287 905.0
PYH3_k127_6773398_4 Subtilase family - - - 3.083e-258 817.0
PYH3_k127_6773398_5 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 2.543e-233 734.0
PYH3_k127_6773398_6 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 537.0
PYH3_k127_6773398_7 Domain of unknown function (DUF4143) K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007964 473.0
PYH3_k127_6773398_8 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004029 424.0
PYH3_k127_6773398_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002382 430.0
PYH3_k127_680537_0 Protein of unknown function (DUF1329) - - - 2.082e-221 694.0
PYH3_k127_680537_1 Methylamine dehydrogenase heavy chain (MADH) K15229 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009886 338.0
PYH3_k127_680537_2 Methylamine dehydrogenase, L chain K15228 - 1.4.9.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001674 270.0
PYH3_k127_680537_3 Methylamine dehydrogenase accessory protein MauD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000007872 250.0
PYH3_k127_680537_4 Methylamine utilisation protein MauE - - - 0.000000000000000000000000000000000001762 145.0
PYH3_k127_680537_5 Cytochrome c - - - 0.0000000000000000000000000001753 121.0
PYH3_k127_680537_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000001675 93.0
PYH3_k127_6806651_0 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1759.0
PYH3_k127_6806651_1 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit K00166 - 1.2.4.4 1.779e-209 659.0
PYH3_k127_6806651_10 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007272 300.0
PYH3_k127_6806651_11 Thioesterase K07107,K12500 - - 0.000000000000000000000000000000000000000000000000001073 191.0
PYH3_k127_6806651_12 NUDIX domain - - - 0.00000000000000000000000000001771 124.0
PYH3_k127_6806651_13 SMART Cold shock protein K03704 - - 0.000000000000000000000000001916 112.0
PYH3_k127_6806651_2 Transketolase, C-terminal domain K00167 - 1.2.4.4 7.289e-195 612.0
PYH3_k127_6806651_3 Amidase K01426 - 3.5.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 572.0
PYH3_k127_6806651_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 564.0
PYH3_k127_6806651_5 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 550.0
PYH3_k127_6806651_6 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005863 541.0
PYH3_k127_6806651_7 2-oxoacid dehydrogenases acyltransferase (catalytic domain) K09699 - 2.3.1.168 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001037 500.0
PYH3_k127_6806651_8 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000888 396.0
PYH3_k127_6806651_9 Phosphoenolpyruvate phosphomutase K20454 - 4.1.3.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009846 387.0
PYH3_k127_6903685_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008999 455.0
PYH3_k127_6903685_1 ABC transporter K02056 - 3.6.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006349 371.0
PYH3_k127_6963925_0 PFAM extracellular solute-binding protein family 1 K05813 - - 1.032e-236 749.0
PYH3_k127_6963925_1 Pilus retraction K02669,K12203 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007602 582.0
PYH3_k127_6963925_10 PFAM beta-lactamase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000044 275.0
PYH3_k127_6963925_11 Glutathione peroxidase K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000004727 256.0
PYH3_k127_6963925_13 2-hydroxychromene-2-carboxylate isomerase - - - 0.000000000000000000000004691 104.0
PYH3_k127_6963925_14 Transposase IS116 IS110 IS902 family protein K07486 - - 0.00000009437 57.0
PYH3_k127_6963925_15 signal transduction protein containing sensor and EAL - - - 0.0000002405 54.0
PYH3_k127_6963925_16 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0001317 49.0
PYH3_k127_6963925_2 twitching motility protein K02670 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007858 581.0
PYH3_k127_6963925_3 PFAM binding-protein-dependent transport systems inner membrane component K05814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 494.0
PYH3_k127_6963925_4 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
PYH3_k127_6963925_5 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002989 464.0
PYH3_k127_6963925_6 THUMP domain K07444 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 435.0
PYH3_k127_6963925_7 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002987 355.0
PYH3_k127_6963925_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000057 291.0
PYH3_k127_6963925_9 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009441 275.0
PYH3_k127_6972597_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 1.746e-205 648.0
PYH3_k127_6972597_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 366.0
PYH3_k127_6972597_2 Belongs to the UPF0301 (AlgH) family K07735 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000812 259.0
PYH3_k127_6972597_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000006424 252.0
PYH3_k127_6972597_4 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000003772 209.0
PYH3_k127_6972597_5 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.00000000000000000000000000000000000009164 147.0
PYH3_k127_7002507_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 0.0 1046.0
PYH3_k127_7002507_1 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 374.0
PYH3_k127_7002507_2 Fe-S oxidoreductase K21834 - - 0.000000000000000000000000000000000000000000000000000000000000003615 218.0
PYH3_k127_7002507_3 - - - - 0.00000000000000000000000000002426 125.0
PYH3_k127_7002507_4 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000003877 74.0
PYH3_k127_7015333_0 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 8.494e-239 751.0
PYH3_k127_7015333_1 AI-2E family transporter - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 403.0
PYH3_k127_7015333_10 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000003542 113.0
PYH3_k127_7015333_11 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000002889 92.0
PYH3_k127_7015333_12 Sodium Bile acid symporter family - - - 0.00000000000000006845 88.0
PYH3_k127_7015333_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006007 351.0
PYH3_k127_7015333_3 Transcriptional regulator K09017 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000006047 271.0
PYH3_k127_7015333_4 phosphinothricin N-acetyltransferase activity K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000007217 236.0
PYH3_k127_7015333_5 dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000005436 221.0
PYH3_k127_7015333_6 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000000002106 190.0
PYH3_k127_7015333_7 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.000000000000000000000000000000000000000000001676 175.0
PYH3_k127_7015333_9 Haem-degrading - - - 0.00000000000000000000000000000000005429 139.0
PYH3_k127_7021887_0 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004745 394.0
PYH3_k127_7021887_1 PFAM UspA domain protein K07090 - - 0.00000000000000000000000000000005384 138.0
PYH3_k127_7021887_2 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.000000000000000000000000000001802 121.0
PYH3_k127_7021887_3 - - - - 0.000000000000000000005034 104.0
PYH3_k127_7021887_4 nitric oxide dioxygenase activity K07140 - - 0.0003525 44.0
PYH3_k127_7044222_0 extracellular solute-binding protein, family 5 K02035 - - 5.947e-307 945.0
PYH3_k127_7044222_1 PFAM Mandelate racemase muconate lactonizing K01856,K02549 - 4.2.1.113,5.5.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005366 572.0
PYH3_k127_7044222_10 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007585 387.0
PYH3_k127_7044222_11 BFD domain protein 2Fe-2S -binding domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 374.0
PYH3_k127_7044222_12 FAD dependent oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006454 323.0
PYH3_k127_7044222_13 Protein of unknown function (DUF2863) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002859 314.0
PYH3_k127_7044222_14 Belongs to the ABC transporter superfamily K02031 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002666 288.0
PYH3_k127_7044222_15 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006578 267.0
PYH3_k127_7044222_16 oxidoreductase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001927 263.0
PYH3_k127_7044222_17 Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions K02553 - - 0.00000000000000000000000000000000000000001236 158.0
PYH3_k127_7044222_18 2Fe-2S iron-sulfur cluster binding domain - - - 0.000000000000000000000105 104.0
PYH3_k127_7044222_2 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001514 556.0
PYH3_k127_7044222_3 Belongs to the ABC transporter superfamily K02032,K12372 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 554.0
PYH3_k127_7044222_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005447 527.0
PYH3_k127_7044222_5 Belongs to the arginase family K01476,K01480,K12255,K18459 - 3.5.3.1,3.5.3.11,3.5.3.17,3.5.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006644 521.0
PYH3_k127_7044222_6 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 522.0
PYH3_k127_7044222_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002688 441.0
PYH3_k127_7044222_8 LysR family transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001724 428.0
PYH3_k127_7044222_9 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 416.0
PYH3_k127_7069956_0 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005625 561.0
PYH3_k127_7069956_1 Trypsin K08070 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 493.0
PYH3_k127_7069956_10 DNA alkylation repair enzyme - - - 0.0000000000000000000000000000000000000000000000000001193 194.0
PYH3_k127_7069956_11 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000004526 169.0
PYH3_k127_7069956_12 Glyoxalase bleomycin resistance protein dioxygenase K06996 - - 0.00000000000000000000000000000000000000005876 157.0
PYH3_k127_7069956_13 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000000004454 151.0
PYH3_k127_7069956_14 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000001035 129.0
PYH3_k127_7069956_15 - - - - 0.00000000000000000000000000000001861 132.0
PYH3_k127_7069956_16 GCN5-related N-acetyl-transferase K06975 - - 0.00000000000000000000000001645 111.0
PYH3_k127_7069956_17 Heavy-metal resistance - - - 0.00000000000000867 82.0
PYH3_k127_7069956_2 rieske 2fe-2s K00499 - 1.14.15.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 426.0
PYH3_k127_7069956_3 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005042 419.0
PYH3_k127_7069956_4 Putative neutral zinc metallopeptidase K07054 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001112 388.0
PYH3_k127_7069956_5 class I DNA-(apurinic or apyrimidinic site) endonuclease activity K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 359.0
PYH3_k127_7069956_6 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001587 345.0
PYH3_k127_7069956_7 Two component transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 301.0
PYH3_k127_7069956_8 Thioredoxin K07396 - - 0.000000000000000000000000000000000000000000000000000001568 198.0
PYH3_k127_7069956_9 Threonyl and Alanyl tRNA synthetase second additional domain K01872 - 6.1.1.7 0.00000000000000000000000000000000000000000000000000005524 196.0
PYH3_k127_7131376_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 8.64e-290 904.0
PYH3_k127_7131376_1 Belongs to the DEAD box helicase family K05592 - 3.6.4.13 2.367e-201 643.0
PYH3_k127_7131376_10 glyoxalase bleomycin resistance protein dioxygenase - - - 0.0000000000000000000000000000000000000000000000000000000000001813 214.0
PYH3_k127_7131376_11 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000002413 219.0
PYH3_k127_7131376_12 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000001547 202.0
PYH3_k127_7131376_13 DNA-binding - - - 0.000000000000000000000000000000000000000000000000000004334 196.0
PYH3_k127_7131376_14 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000000004678 171.0
PYH3_k127_7131376_16 - - - - 0.000000000000000000000000000000000000001319 150.0
PYH3_k127_7131376_17 YHS domain protein - - - 0.000000000000000000000000000000000004803 144.0
PYH3_k127_7131376_18 protein conserved in bacteria K09931 - - 0.000000000000000000000000000000001516 139.0
PYH3_k127_7131376_19 PIN domain - - - 0.0000000000000000000000000001502 121.0
PYH3_k127_7131376_2 PFAM Phospholipase D Transphosphatidylase K06131 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 539.0
PYH3_k127_7131376_20 Acetoacetate decarboxylase (ADC) K01574 - 4.1.1.4 0.0000000000000000000000000004413 124.0
PYH3_k127_7131376_21 Cytochrome c - - - 0.000000001428 59.0
PYH3_k127_7131376_22 positive regulation of growth - - - 0.00000003136 59.0
PYH3_k127_7131376_23 Cytochrome c - - - 0.0000004377 55.0
PYH3_k127_7131376_3 Enoyl-(Acyl carrier protein) reductase K00019 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001258 391.0
PYH3_k127_7131376_4 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006567 357.0
PYH3_k127_7131376_5 SMART extracellular solute-binding protein, family 3 K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004311 314.0
PYH3_k127_7131376_6 AIR synthase related protein, N-terminal domain K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003035 286.0
PYH3_k127_7131376_7 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003315 265.0
PYH3_k127_7131376_8 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001215 249.0
PYH3_k127_7131376_9 Aldolase K11645 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000001825 233.0
PYH3_k127_7137625_0 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006626 349.0
PYH3_k127_7137625_1 Glyoxalase-like domain K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000001436 225.0
PYH3_k127_7137625_2 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) component and related enzymes K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000001885 207.0
PYH3_k127_7137625_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000001732 203.0
PYH3_k127_7137625_4 Ribbon-helix-helix domain - - - 0.000000000000000000000000000000000000000003401 157.0
PYH3_k127_7176912_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001617 466.0
PYH3_k127_7176912_1 Threonine dehydratase K01754 GO:0003674,GO:0003824,GO:0004794,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006549,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009097,GO:0009507,GO:0009536,GO:0009987,GO:0016053,GO:0016829,GO:0016840,GO:0016841,GO:0019752,GO:0042802,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.3.1.19 0.00000001835 55.0
PYH3_k127_7179905_0 PFAM carboxyl transferase K01615 - 4.1.1.70 1.21e-297 923.0
PYH3_k127_7179905_1 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001034 560.0
PYH3_k127_7179905_2 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008195 481.0
PYH3_k127_7179905_3 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 400.0
PYH3_k127_7179905_4 AAA domain K07133 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000009611 280.0
PYH3_k127_7179905_5 PFAM peptidase - - - 0.000000000000000000000000000000000000000000006982 170.0
PYH3_k127_7179905_6 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000000000000000000000000002478 142.0
PYH3_k127_7179905_7 Biotin-requiring enzyme - - - 0.000000000000000000002547 94.0
PYH3_k127_7179905_8 cellulase activity - - - 0.0000005462 63.0
PYH3_k127_7179905_9 Bacterial Ig-like domain (group 3) - - - 0.00001525 58.0
PYH3_k127_7273229_0 phosphinothricin N-acetyltransferase activity K09181 - - 0.00000000000000000000000000000000000000000000000000000000000000000002068 237.0
PYH3_k127_7273229_1 Sodium Bile acid symporter family - - - 0.000000000000004788 83.0
PYH3_k127_7273229_2 secondary active sulfate transmembrane transporter activity K03321 - - 0.0000000000003162 71.0
PYH3_k127_7368843_0 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008493 430.0
PYH3_k127_7368843_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007758 406.0
PYH3_k127_7368843_2 4Fe-4S dicluster domain K00184 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 365.0
PYH3_k127_7368843_3 - - - - 0.000000000000000000000000000006214 120.0
PYH3_k127_7374100_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00325 - 1.6.1.2 4.561e-235 744.0
PYH3_k127_7374100_1 Alanine dehydrogenase/PNT, N-terminal domain K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 540.0
PYH3_k127_7374100_2 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 526.0
PYH3_k127_7374100_3 Nicotinamidase K08281 - 3.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003335 298.0
PYH3_k127_7374100_4 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000000002251 195.0
PYH3_k127_7374100_5 4TM region of pyridine nucleotide transhydrogenase, mitoch K00324 - 1.6.1.2 0.00000000000000000000000000000000000000000000008489 169.0
PYH3_k127_7374920_0 ABC-type dipeptide transport system periplasmic component K02035 - - 5.357e-218 691.0
PYH3_k127_7374920_1 Catalyzes the synthesis of acetoacetyl coenzyme A from two molecules of acetyl coenzyme A. It can also act as a thiolase, catalyzing the reverse reaction and generating two-carbon units from the four-carbon product of fatty acid oxidation K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005407 591.0
PYH3_k127_7374920_10 Belongs to the ParB family K03497 - - 0.0000000000000135 79.0
PYH3_k127_7374920_11 nuclear chromosome segregation K09971,K21449 - - 0.000105 52.0
PYH3_k127_7374920_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005044 503.0
PYH3_k127_7374920_3 Peptidase family M28 K06016 - 3.5.1.6,3.5.1.87 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003015 501.0
PYH3_k127_7374920_4 Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01459 - 3.5.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 492.0
PYH3_k127_7374920_5 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002052 421.0
PYH3_k127_7374920_6 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002379 416.0
PYH3_k127_7374920_7 Belongs to the ABC transporter superfamily K02031 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 412.0
PYH3_k127_7374920_8 Family of unknown function (DUF1028) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006743 314.0
PYH3_k127_7374920_9 Pyridoxal-phosphate dependent enzyme K01751 - 4.3.1.15 0.000000000000003885 76.0
PYH3_k127_7375437_0 Poly-beta-hydroxybutyrate polymerase K03821 - - 1.405e-207 664.0
PYH3_k127_7375437_1 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001572 549.0
PYH3_k127_7375437_10 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000000000000000000000000000003944 200.0
PYH3_k127_7375437_11 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000000001542 191.0
PYH3_k127_7375437_12 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000001953 169.0
PYH3_k127_7375437_13 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000000002927 166.0
PYH3_k127_7375437_14 - - - - 0.00000000000000000000000000000000000000001691 164.0
PYH3_k127_7375437_15 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0000000000000000000000000000000000000001278 155.0
PYH3_k127_7375437_16 acetyltransferase - - - 0.000000000000000000000000000000000001748 144.0
PYH3_k127_7375437_17 Rubrerythrin - - - 0.0000000000000000000000000000000000222 148.0
PYH3_k127_7375437_18 DUF167 K09131 - - 0.00000000000000000009413 91.0
PYH3_k127_7375437_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 534.0
PYH3_k127_7375437_20 Glutathione-dependent formaldehyde-activating - - - 0.00000000002257 67.0
PYH3_k127_7375437_21 SnoaL-like domain - - - 0.00000001619 61.0
PYH3_k127_7375437_22 MacB-like periplasmic core domain K02004 - - 0.0001224 52.0
PYH3_k127_7375437_3 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 537.0
PYH3_k127_7375437_4 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001277 446.0
PYH3_k127_7375437_5 Carbon-nitrogen hydrolase K01501,K01502 GO:0000257,GO:0003674,GO:0003824,GO:0008150,GO:0009987,GO:0016043,GO:0016787,GO:0016810,GO:0016815,GO:0018762,GO:0022607,GO:0043933,GO:0044085,GO:0051259,GO:0051260,GO:0065003,GO:0071840 3.5.5.1,3.5.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 431.0
PYH3_k127_7375437_6 abc transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001163 364.0
PYH3_k127_7375437_7 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000268 272.0
PYH3_k127_7375437_8 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006353 285.0
PYH3_k127_7375437_9 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001421 260.0
PYH3_k127_7376289_0 Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34 K15461 - 2.1.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001801 523.0
PYH3_k127_7376289_1 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000003735 196.0
PYH3_k127_7376289_2 Domain of unknown function (DUF4437) - - - 0.00000002613 56.0
PYH3_k127_7380968_0 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 451.0
PYH3_k127_7380968_1 ABC-type transport system, periplasmic component surface lipoprotein K02058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 359.0
PYH3_k127_7380968_2 Belongs to the binding-protein-dependent transport system permease family K02057 - - 0.00000000000000002885 81.0
PYH3_k127_7382671_0 iron ion homeostasis - - - 1.839e-293 917.0
PYH3_k127_7382671_1 His Kinase A (phosphoacceptor) domain - - - 3.875e-266 830.0
PYH3_k127_7382671_10 - - - - 0.000000000000000000000000002333 112.0
PYH3_k127_7382671_11 BON domain - - - 0.00000000000000000000006164 101.0
PYH3_k127_7382671_12 Protein of unknown function (DUF3309) - - - 0.0000000000000000002448 89.0
PYH3_k127_7382671_13 Collagen, type XXVII, alpha K19721 GO:0001501,GO:0001503,GO:0002062,GO:0002063,GO:0003413,GO:0003416,GO:0003417,GO:0003418,GO:0003431,GO:0003433,GO:0003674,GO:0005198,GO:0005201,GO:0005575,GO:0005576,GO:0005581,GO:0005583,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0007275,GO:0008150,GO:0009653,GO:0009790,GO:0009887,GO:0009888,GO:0009987,GO:0012505,GO:0016043,GO:0030154,GO:0030198,GO:0030282,GO:0030903,GO:0031012,GO:0031214,GO:0031974,GO:0032501,GO:0032502,GO:0032991,GO:0035265,GO:0040007,GO:0043062,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044420,GO:0044421,GO:0044422,GO:0044424,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0048468,GO:0048513,GO:0048562,GO:0048568,GO:0048570,GO:0048589,GO:0048598,GO:0048705,GO:0048731,GO:0048856,GO:0048869,GO:0051216,GO:0060348,GO:0060349,GO:0060350,GO:0060351,GO:0061448,GO:0062023,GO:0070013,GO:0071840,GO:0098643,GO:0098644,GO:0098868,GO:0099080,GO:0099081,GO:0099512 - 0.000000000000769 79.0
PYH3_k127_7382671_14 PFAM transport-associated K04065 - - 0.00000000004805 64.0
PYH3_k127_7382671_2 Domain of unknown function (DUF3943) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 569.0
PYH3_k127_7382671_3 cheY-homologous receiver domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 432.0
PYH3_k127_7382671_4 Beta/gamma crystallins - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 371.0
PYH3_k127_7382671_5 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003005 361.0
PYH3_k127_7382671_6 cell septum assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008443 310.0
PYH3_k127_7382671_7 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 296.0
PYH3_k127_7382671_8 - - - - 0.0000000000000000000000000000000000000000001229 168.0
PYH3_k127_7382671_9 phosphatidate phosphatase activity K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000575 166.0
PYH3_k127_7384644_0 Circularly permuted ATP-grasp type 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 511.0
PYH3_k127_7384644_1 A predicted alpha-helical domain with a conserved ER motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004898 448.0
PYH3_k127_7393291_0 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00383 - 1.8.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008182 602.0
PYH3_k127_7393291_1 Domain of unknown function (DUF4331) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001342 388.0
PYH3_k127_7393291_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004403 318.0
PYH3_k127_7393291_3 PFAM alpha beta hydrolase fold - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0016020,GO:0044424,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 298.0
PYH3_k127_7393291_4 - - - - 0.00000000000000000000000003766 115.0
PYH3_k127_7394411_0 Proton-conducting membrane transporter K12141 - - 8.064e-245 779.0
PYH3_k127_7394411_1 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 598.0
PYH3_k127_7394411_2 NADH dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 476.0
PYH3_k127_7394411_3 NADH ubiquinone plastoquinone (Complex I) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 342.0
PYH3_k127_7394411_4 hydrogenase 4 membrane K12140 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 317.0
PYH3_k127_7401062_0 NADH ubiquinone oxidoreductase subunit 5 (Chain L) Multisubunit Na H antiporter, MnhA subunit K00341,K05559 - 1.6.5.3 1.564e-310 987.0
PYH3_k127_7401062_1 Pyridoxal-dependent decarboxylase conserved domain K01593 - 4.1.1.105,4.1.1.28 4.317e-234 734.0
PYH3_k127_7401062_10 Succinyl-CoA ligase like flavodoxin domain K09181 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 366.0
PYH3_k127_7401062_11 Belongs to the TrpC family K01609 - 4.1.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 325.0
PYH3_k127_7401062_12 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 320.0
PYH3_k127_7401062_13 Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 314.0
PYH3_k127_7401062_14 Rhomboid family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 305.0
PYH3_k127_7401062_15 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005855 271.0
PYH3_k127_7401062_16 Phosphoglycolate phosphatase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000002323 221.0
PYH3_k127_7401062_17 Sodium/hydrogen exchanger family - - - 0.00000000000000000000000000000000000000000000000000000000000006004 229.0
PYH3_k127_7401062_18 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.0000000000000000000000000000000000000000000000000000000000001487 221.0
PYH3_k127_7401062_19 Na+/H+ ion antiporter subunit - - - 0.000000000000000000000000000000000000000000000000000000006709 214.0
PYH3_k127_7401062_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 1.719e-222 699.0
PYH3_k127_7401062_20 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000001134 191.0
PYH3_k127_7401062_21 ApaG domain K06195 - - 0.0000000000000000000000000000000000000000000000000002978 190.0
PYH3_k127_7401062_22 NAD dependent epimerase/dehydratase family - - - 0.00000000000000000000000000000000000000000000918 171.0
PYH3_k127_7401062_23 Belongs to the class-I aminoacyl-tRNA synthetase family K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000009249 171.0
PYH3_k127_7401062_24 NADH-ubiquinone/plastoquinone oxidoreductase chain 4L K05560 - - 0.000000000000000000000000000000000002377 150.0
PYH3_k127_7401062_25 Multisubunit Na H antiporter, MnhG subunit K05564,K05571 - - 0.00000000000000000000000000004224 124.0
PYH3_k127_7401062_26 PFAM multiple resistance and pH regulation protein F K05563 - - 0.000000000000000000000001262 105.0
PYH3_k127_7401062_27 PD-(D/E)XK nuclease superfamily - - - 0.000000000000000000000001437 105.0
PYH3_k127_7401062_28 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.0000000000000961 71.0
PYH3_k127_7401062_29 - - - - 0.0000000000001419 78.0
PYH3_k127_7401062_3 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 528.0
PYH3_k127_7401062_30 PD-(D/E)XK nuclease superfamily - - - 0.00000000127 63.0
PYH3_k127_7401062_31 Protein of unknown function (DUF2934) - - - 0.0000004411 55.0
PYH3_k127_7401062_4 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 462.0
PYH3_k127_7401062_5 Proton-conducting membrane transporter K00342,K05561,K05568 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 467.0
PYH3_k127_7401062_6 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 444.0
PYH3_k127_7401062_7 PFAM aromatic amino acid beta-eliminating lyase threonine aldolase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 424.0
PYH3_k127_7401062_8 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009736 379.0
PYH3_k127_7401062_9 Membrane-bound lytic murein transglycosylase K08304 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 376.0
PYH3_k127_7405213_0 TRANSCRIPTIONal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005587 297.0
PYH3_k127_7405213_1 - - - - 0.000000000000000000000000000000000000000000000000000000002166 202.0
PYH3_k127_7405213_2 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0001499 45.0
PYH3_k127_7405219_0 AAA domain K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 459.0
PYH3_k127_7405219_1 Nucleotidyl transferase AbiEii toxin, Type IV TA system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002419 243.0
PYH3_k127_7405219_2 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000004059 159.0
PYH3_k127_7405219_3 PFAM HNH endonuclease - - - 0.000001436 56.0
PYH3_k127_7430036_0 PFAM Filamentation induced by cAMP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004479 516.0
PYH3_k127_7430036_1 Nuclease-related domain - - - 0.00000000000000000000000000000000000000000000000000000000000000003738 233.0
PYH3_k127_7430036_10 Protein of unknown function (DUF433) - - - 0.000000000000000001782 88.0
PYH3_k127_7430036_11 Nucleotidyltransferase domain - - - 0.0000000000000001314 82.0
PYH3_k127_7430036_12 N-6 DNA methylase K03427 - 2.1.1.72 0.00000000002014 68.0
PYH3_k127_7430036_2 Conserved Protein - - - 0.0000000000000000000000000000000000000000000000000000000000003771 217.0
PYH3_k127_7430036_3 ADP-ribosylglycohydrolase K05521 - 3.2.2.24 0.0000000000000000000000000000000000000000000000001458 183.0
PYH3_k127_7430036_4 Protein of unknown function (DUF433) - - - 0.00000000000000000000000000000000532 130.0
PYH3_k127_7430036_5 Mut7-C RNAse domain - - - 0.000000000000000000000000000000005694 133.0
PYH3_k127_7430036_6 Winged helix-turn helix K07499 - - 0.0000000000000000000000000000005669 128.0
PYH3_k127_7430036_7 DDE superfamily endonuclease - - - 0.000000000000000000000000000004382 128.0
PYH3_k127_7430036_8 PFAM Uncharacterised protein family UPF0150 - - - 0.00000000000000000000002607 101.0
PYH3_k127_7430036_9 PFAM Filamentation induced by cAMP - - - 0.00000000000000000000004192 102.0
PYH3_k127_7430587_0 Malonate decarboxylase, alpha subunit, transporter K01026 - 2.8.3.1 1.373e-308 957.0
PYH3_k127_7430587_1 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 3.042e-216 686.0
PYH3_k127_7430587_2 3-hydroxy-2-methylbutyryl-CoA dehydrogenase activity K08683 - 1.1.1.178,1.1.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003733 375.0
PYH3_k127_7430587_3 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001689 247.0
PYH3_k127_7430587_4 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.0000000000000000000000000000000001664 138.0
PYH3_k127_7430587_5 Redoxin K03386 - 1.11.1.15 0.000000000000000000000000000000008896 128.0
PYH3_k127_7430587_6 toxin-antitoxin pair type II binding - - - 0.000000000000000126 82.0
PYH3_k127_7430587_7 trans-aconitate 2-methyltransferase activity K00563,K02169,K16868 - 2.1.1.187,2.1.1.197,2.1.1.265 0.000000000000000521 88.0
PYH3_k127_7445392_0 FAD linked oxidase domain protein - - - 0.0 1994.0
PYH3_k127_7445392_1 Catalyzes cross-linking of the peptidoglycan cell wall K05515 - 3.4.16.4 1.581e-266 834.0
PYH3_k127_7445392_10 Lysine exporter protein (Lyse ygga) K11250 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001292 291.0
PYH3_k127_7445392_11 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002574 275.0
PYH3_k127_7445392_12 PFAM VanZ family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000259 285.0
PYH3_k127_7445392_13 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.000000000000000000000000000000000000000000000000000000000000000000000000000005852 269.0
PYH3_k127_7445392_14 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001872 258.0
PYH3_k127_7445392_15 Alpha beta K07018 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001346 254.0
PYH3_k127_7445392_16 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000001903 258.0
PYH3_k127_7445392_17 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.00000000000000000000000000000000000000000000000000000000000000000003298 233.0
PYH3_k127_7445392_18 rod shape-determining protein MreD K03571 - - 0.0000000000000000000000000000000000000000000000000000000000000000001627 237.0
PYH3_k127_7445392_19 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000001216 251.0
PYH3_k127_7445392_2 TIGRFAM cell shape determining protein, MreB Mrl family K03569 - - 2.285e-205 641.0
PYH3_k127_7445392_20 HIT domain - - - 0.000000000000000000000000000000000000000000000007316 176.0
PYH3_k127_7445392_21 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000001731 179.0
PYH3_k127_7445392_22 Ferredoxin - - - 0.0000000000000000000000000000000000000000000009851 167.0
PYH3_k127_7445392_23 SMART Transport-associated and nodulation region - - - 0.00000000000000000000000000000000000000000087 164.0
PYH3_k127_7445392_24 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000007155 153.0
PYH3_k127_7445392_25 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000001503 164.0
PYH3_k127_7445392_26 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K01947,K03525 - 2.7.1.33,6.3.4.15 0.0000000000000000000000000000000000000817 156.0
PYH3_k127_7445392_27 LppC putative lipoprotein K07121 - - 0.000000000000000000000000000000000005803 151.0
PYH3_k127_7445392_28 Belongs to the UPF0102 family K07460 - - 0.0000000000000000000000000001474 119.0
PYH3_k127_7445392_29 Belongs to the UPF0250 family K09158 - - 0.0000000000000000000000000001659 123.0
PYH3_k127_7445392_3 Acetylornithine deacetylase Succinyl-diaminopimelate desuccinylase and related deacylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006112 602.0
PYH3_k127_7445392_30 Lactoylglutathione lyase and related lyases - - - 0.00000000000000000000000006066 116.0
PYH3_k127_7445392_31 PFAM Sporulation domain protein - - - 0.00000000001709 74.0
PYH3_k127_7445392_32 - - - - 0.0000000004963 67.0
PYH3_k127_7445392_4 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001901 541.0
PYH3_k127_7445392_5 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002406 514.0
PYH3_k127_7445392_6 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 465.0
PYH3_k127_7445392_7 PFAM Serine threonine protein kinase-related - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 377.0
PYH3_k127_7445392_8 Involved in formation and maintenance of cell shape K03570 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009508 321.0
PYH3_k127_7445392_9 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001047 324.0
PYH3_k127_7447273_0 Integrase K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 310.0
PYH3_k127_7447273_1 Transposase IS116 IS110 IS902 family protein K07486 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009784 278.0
PYH3_k127_7447273_2 Helix-turn-helix domain - - - 0.0000000000000000000000000000000000608 136.0
PYH3_k127_7465488_0 FAD dependent oxidoreductase central domain - - - 0.0 1358.0
PYH3_k127_7465488_1 Peptidase M61 - - - 1.335e-213 679.0
PYH3_k127_7465488_2 flavoprotein involved in K transport - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 513.0
PYH3_k127_7465488_3 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001932 484.0
PYH3_k127_7465488_4 amino acid K03294,K19540 GO:0003333,GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006040,GO:0006082,GO:0006520,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006865,GO:0008150,GO:0008152,GO:0008509,GO:0008514,GO:0009056,GO:0009063,GO:0009987,GO:0015075,GO:0015171,GO:0015179,GO:0015291,GO:0015297,GO:0015318,GO:0015711,GO:0015807,GO:0015849,GO:0016020,GO:0016021,GO:0016054,GO:0019752,GO:0022804,GO:0022857,GO:0030389,GO:0030392,GO:0030393,GO:0031224,GO:0031226,GO:0034220,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044425,GO:0044459,GO:0044464,GO:0046348,GO:0046395,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071704,GO:0071705,GO:0071944,GO:0098656,GO:1901135,GO:1901136,GO:1901281,GO:1901564,GO:1901565,GO:1901575,GO:1902475,GO:1903825,GO:1905039 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006259 417.0
PYH3_k127_7465488_5 Peptidase C14 caspase catalytic subunit p20 - - - 0.0000000000000000000000000000000000000000000004316 179.0
PYH3_k127_7465488_6 MobA-like NTP transferase domain K07141 - 2.7.7.76 0.00000000000000000000000000000000000000000002929 167.0
PYH3_k127_7465488_7 COG0183 Acetyl-CoA acetyltransferase - - - 0.00000000000000000000000005149 114.0
PYH3_k127_7465488_8 - - - - 0.0000000005803 68.0
PYH3_k127_7465488_9 Histone methylation protein DOT1 - - - 0.0000002405 55.0
PYH3_k127_7469704_0 Protein of unknown function (DUF1298) - - - 5.846e-237 742.0
PYH3_k127_7469704_1 Putative transposase - - - 0.0000000000000000000000000000000000000000000000000000000000003606 213.0
PYH3_k127_7469704_2 - - - - 0.0000682 47.0
PYH3_k127_7491952_0 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 550.0
PYH3_k127_7491952_1 Periplasmic solute binding protein K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 451.0
PYH3_k127_7491952_2 ABC-3 protein K02075 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 347.0
PYH3_k127_7496155_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1429.0
PYH3_k127_7496155_1 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1301.0
PYH3_k127_7496155_10 PFAM major facilitator superfamily MFS_1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 566.0
PYH3_k127_7496155_11 AFG1-like ATPase K06916 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 502.0
PYH3_k127_7496155_12 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 486.0
PYH3_k127_7496155_13 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005207 482.0
PYH3_k127_7496155_14 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044444,GO:0044464 1.1.1.36 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 444.0
PYH3_k127_7496155_15 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 414.0
PYH3_k127_7496155_16 Transcriptional regulatory protein, C terminal K02483,K07659 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009447 408.0
PYH3_k127_7496155_17 Periplasmic domain of Sensor histidine kinase RisS K07638 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001365 402.0
PYH3_k127_7496155_18 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001197 370.0
PYH3_k127_7496155_19 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007308 338.0
PYH3_k127_7496155_2 Dehydrogenase K00382 GO:0003674,GO:0003824,GO:0004148,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006084,GO:0006085,GO:0006086,GO:0006090,GO:0006139,GO:0006163,GO:0006164,GO:0006464,GO:0006637,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009150,GO:0009152,GO:0009165,GO:0009259,GO:0009260,GO:0009987,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0018130,GO:0018335,GO:0019362,GO:0019438,GO:0019538,GO:0019637,GO:0019693,GO:0019752,GO:0031974,GO:0031981,GO:0032787,GO:0032991,GO:0033865,GO:0033866,GO:0033875,GO:0034030,GO:0034032,GO:0034033,GO:0034641,GO:0034654,GO:0035383,GO:0035384,GO:0036211,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043412,GO:0043436,GO:0043543,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044422,GO:0044424,GO:0044428,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0045239,GO:0045240,GO:0045252,GO:0045254,GO:0046390,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0061732,GO:0070013,GO:0071616,GO:0071704,GO:0072521,GO:0072522,GO:0072524,GO:0090407,GO:0106077,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902494,GO:1990204,GO:1990234 1.8.1.4 6.112e-239 745.0
PYH3_k127_7496155_20 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005782 320.0
PYH3_k127_7496155_21 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003965 300.0
PYH3_k127_7496155_22 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004149 304.0
PYH3_k127_7496155_23 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000009136 282.0
PYH3_k127_7496155_24 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001997 282.0
PYH3_k127_7496155_25 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006187 299.0
PYH3_k127_7496155_26 Polyhydroxyalkanoate synthesis repressor PhaR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003663 268.0
PYH3_k127_7496155_27 phosphoserine phosphatase K01079 - 3.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000007855 264.0
PYH3_k127_7496155_28 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000007543 242.0
PYH3_k127_7496155_29 SMART protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000007283 237.0
PYH3_k127_7496155_3 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.173e-226 708.0
PYH3_k127_7496155_30 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000001864 218.0
PYH3_k127_7496155_31 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.00000000000000000000000000000000000000000000000000000000287 207.0
PYH3_k127_7496155_32 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789,K14742 - 2.3.1.128 0.00000000000000000000000000000000000000000000000002625 183.0
PYH3_k127_7496155_33 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.0000000000000000000000000000000000000003788 149.0
PYH3_k127_7496155_34 Peptidase M22 glycoprotease K14742 - - 0.000000000000000000000000000000000009614 148.0
PYH3_k127_7496155_35 Protein of unknown function (DUF465) - - - 0.0000000000000002821 80.0
PYH3_k127_7496155_36 - - - - 0.000000000000001346 87.0
PYH3_k127_7496155_38 - - - - 0.0003345 45.0
PYH3_k127_7496155_4 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 2.901e-222 694.0
PYH3_k127_7496155_5 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.02e-216 681.0
PYH3_k127_7496155_6 Poly(R)-hydroxyalkanoic acid synthase, class I K03821 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 9.954e-210 668.0
PYH3_k127_7496155_7 helicase K03722 - 3.6.4.12 2.855e-199 642.0
PYH3_k127_7496155_8 Belongs to the thiolase family K00626 - 2.3.1.9 7.479e-199 627.0
PYH3_k127_7496155_9 Belongs to the thiolase family K00626 - 2.3.1.9 8.355e-195 613.0
PYH3_k127_7515057_0 Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle K01595 - 4.1.1.31 9.683e-301 949.0
PYH3_k127_7515057_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01916,K01950 - 6.3.1.5,6.3.5.1 5.037e-235 738.0
PYH3_k127_7515057_10 Catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 383.0
PYH3_k127_7515057_11 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000465 307.0
PYH3_k127_7515057_12 LytTr DNA-binding domain K08083 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000167 262.0
PYH3_k127_7515057_13 HemY protein N-terminus K02498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008235 263.0
PYH3_k127_7515057_14 EamA-like transporter family K15268 - - 0.000000000000000000000000000000000000000000000000000000000000000000000008576 254.0
PYH3_k127_7515057_15 Histidine kinase K08082 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000001527 246.0
PYH3_k127_7515057_16 Smr protein MutS2 - - - 0.0000000000000000000000000000000000000000000000000000000000001069 223.0
PYH3_k127_7515057_17 Nitrogen regulatory protein P-II K04751,K04752 - - 0.0000000000000000000000000000000000000000000000000000000105 200.0
PYH3_k127_7515057_18 HemX, putative uroporphyrinogen-III C-methyltransferase K02496,K13543 - 2.1.1.107,4.2.1.75 0.000000000000000000000000000000000000000000000000003514 195.0
PYH3_k127_7515057_19 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000005765 186.0
PYH3_k127_7515057_2 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 9.047e-234 731.0
PYH3_k127_7515057_20 Endoribonuclease L-PSP K10013 - - 0.0000000000000000000000000000000000000000000000004106 180.0
PYH3_k127_7515057_21 Uroporphyrinogen III synthase K01719 - 4.2.1.75 0.00000000000000001333 93.0
PYH3_k127_7515057_22 UPF0126 domain - - - 0.0000000489 56.0
PYH3_k127_7515057_23 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.000009705 49.0
PYH3_k127_7515057_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 7.316e-207 653.0
PYH3_k127_7515057_4 TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 604.0
PYH3_k127_7515057_5 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 522.0
PYH3_k127_7515057_6 TIGRFAM TRAP dicarboxylate transporter, DctP subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 478.0
PYH3_k127_7515057_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005605 468.0
PYH3_k127_7515057_8 Peptidogalycan biosysnthesis/recognition K09919 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008021 469.0
PYH3_k127_7515057_9 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 395.0
PYH3_k127_7534803_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.498e-253 799.0
PYH3_k127_7534803_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002715 585.0
PYH3_k127_7534803_2 Acetyl-CoA hydrolase/transferase C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003961 567.0
PYH3_k127_7534803_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002557 422.0
PYH3_k127_7534803_4 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 399.0
PYH3_k127_7534803_5 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000005556 255.0
PYH3_k127_7534803_6 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000001555 214.0
PYH3_k127_7534803_7 Preprotein translocase K03210 - - 0.00000000000000000000000000000001873 130.0
PYH3_k127_7579172_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1483.0
PYH3_k127_7579172_1 pyruvate phosphate dikinase K01006,K01007 - 2.7.9.1,2.7.9.2 0.0 1347.0
PYH3_k127_7579172_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 1.915e-230 727.0
PYH3_k127_7579172_100 COG3133 Outer membrane lipoprotein K06077 - - 0.0000001267 58.0
PYH3_k127_7579172_101 - - - - 0.0000002273 58.0
PYH3_k127_7579172_102 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.000001756 53.0
PYH3_k127_7579172_104 Protein of unknown function (DUF721) - - - 0.0005437 49.0
PYH3_k127_7579172_11 RNB K01147 - 3.1.13.1 3.691e-220 700.0
PYH3_k127_7579172_12 Belongs to the MurCDEF family K01924 - 6.3.2.8 9.277e-219 687.0
PYH3_k127_7579172_13 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 6.071e-217 688.0
PYH3_k127_7579172_14 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.42e-214 676.0
PYH3_k127_7579172_15 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 2.96e-211 660.0
PYH3_k127_7579172_16 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 1.627e-208 654.0
PYH3_k127_7579172_17 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 6.544e-202 638.0
PYH3_k127_7579172_18 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 8.211e-202 637.0
PYH3_k127_7579172_19 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 606.0
PYH3_k127_7579172_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1281.0
PYH3_k127_7579172_20 catalyzes the reversible aldol condensation of dihydroxyacetonephosphate and glyceraldehyde 3-phosphate in the Calvin cycle, glycolysis and gluconeogenesis K01624 - 4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 596.0
PYH3_k127_7579172_21 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 GO:0000166,GO:0000226,GO:0001817,GO:0001819,GO:0001906,GO:0001907,GO:0002376,GO:0002791,GO:0002793,GO:0003674,GO:0003824,GO:0004365,GO:0004857,GO:0004866,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005737,GO:0005811,GO:0005829,GO:0005856,GO:0005886,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006417,GO:0006464,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0006915,GO:0006950,GO:0006952,GO:0006955,GO:0006959,GO:0006996,GO:0007010,GO:0007017,GO:0008017,GO:0008092,GO:0008150,GO:0008152,GO:0008219,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009435,GO:0009605,GO:0009607,GO:0009620,GO:0009889,GO:0009890,GO:0009892,GO:0009894,GO:0009987,GO:0010033,GO:0010466,GO:0010468,GO:0010506,GO:0010556,GO:0010558,GO:0010605,GO:0010608,GO:0010629,GO:0010941,GO:0010942,GO:0010951,GO:0012501,GO:0012505,GO:0015630,GO:0015631,GO:0016020,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016241,GO:0016310,GO:0016491,GO:0016620,GO:0016740,GO:0016769,GO:0016903,GO:0017014,GO:0017144,GO:0017148,GO:0018119,GO:0018130,GO:0018193,GO:0018198,GO:0019222,GO:0019318,GO:0019319,GO:0019320,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019538,GO:0019637,GO:0019674,GO:0019693,GO:0019730,GO:0019752,GO:0019828,GO:0019904,GO:0030162,GO:0030234,GO:0030414,GO:0031090,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031329,GO:0031341,GO:0031343,GO:0031640,GO:0031647,GO:0031965,GO:0031967,GO:0031975,GO:0032268,GO:0032269,GO:0032787,GO:0032879,GO:0032880,GO:0032991,GO:0034097,GO:0034248,GO:0034249,GO:0034341,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035605,GO:0035606,GO:0035821,GO:0036094,GO:0036211,GO:0042221,GO:0042802,GO:0042866,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043086,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043412,GO:0043436,GO:0043891,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044092,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044267,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044364,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0045087,GO:0045861,GO:0046031,GO:0046034,GO:0046364,GO:0046365,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0048037,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050662,GO:0050707,GO:0050708,GO:0050714,GO:0050715,GO:0050789,GO:0050790,GO:0050794,GO:0050821,GO:0050832,GO:0050896,GO:0051046,GO:0051047,GO:0051049,GO:0051050,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051222,GO:0051223,GO:0051239,GO:0051240,GO:0051246,GO:0051248,GO:0051287,GO:0051336,GO:0051346,GO:0051402,GO:0051701,GO:0051702,GO:0051704,GO:0051707,GO:0051709,GO:0051712,GO:0051716,GO:0051817,GO:0051818,GO:0051851,GO:0051852,GO:0051873,GO:0051883,GO:0052040,GO:0052042,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052547,GO:0052548,GO:0055086,GO:0055114,GO:0060255,GO:0061134,GO:0061135,GO:0061615,GO:0061620,GO:0061621,GO:0061718,GO:0061844,GO:0065007,GO:0065008,GO:0065009,GO:0070201,GO:0070887,GO:0070997,GO:0071310,GO:0071345,GO:0071346,GO:0071704,GO:0071840,GO:0071944,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0080090,GO:0090087,GO:0090407,GO:0097159,GO:0097452,GO:0097718,GO:0098542,GO:0098772,GO:0140096,GO:1901135,GO:1901137,GO:1901265,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903530,GO:1903532,GO:1904951,GO:1990904,GO:2000112,GO:2000113 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003441 593.0
PYH3_k127_7579172_22 Acts as a magnesium transporter K06213 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 598.0
PYH3_k127_7579172_23 Belongs to the phosphoglycerate kinase family K00927 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 582.0
PYH3_k127_7579172_24 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 567.0
PYH3_k127_7579172_25 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002947 560.0
PYH3_k127_7579172_26 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004013 556.0
PYH3_k127_7579172_27 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002807 565.0
PYH3_k127_7579172_28 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001224 552.0
PYH3_k127_7579172_29 PFAM Protein kinase K11912,K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 556.0
PYH3_k127_7579172_3 Malic enzyme K00029 - 1.1.1.40 0.0 1130.0
PYH3_k127_7579172_30 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000528 543.0
PYH3_k127_7579172_31 response regulator K02667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 539.0
PYH3_k127_7579172_32 Transporter associated domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 504.0
PYH3_k127_7579172_33 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 501.0
PYH3_k127_7579172_34 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006811 485.0
PYH3_k127_7579172_35 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002364 482.0
PYH3_k127_7579172_36 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003849 467.0
PYH3_k127_7579172_37 COG0524 Sugar kinases, ribokinase family K00856 - 2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008284 459.0
PYH3_k127_7579172_38 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 427.0
PYH3_k127_7579172_39 Cell wall formation K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005679 410.0
PYH3_k127_7579172_4 Belongs to the transketolase family K00615 - 2.2.1.1 3.687e-289 904.0
PYH3_k127_7579172_40 Subtilase family K14645 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002847 428.0
PYH3_k127_7579172_41 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002188 392.0
PYH3_k127_7579172_42 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003789 386.0
PYH3_k127_7579172_43 Protein of unknown function (DUF815) K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002948 369.0
PYH3_k127_7579172_44 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 360.0
PYH3_k127_7579172_45 TonB C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 370.0
PYH3_k127_7579172_46 KR domain K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 353.0
PYH3_k127_7579172_47 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001706 352.0
PYH3_k127_7579172_48 Pregnancy-associated plasma protein-A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002079 345.0
PYH3_k127_7579172_49 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004851 326.0
PYH3_k127_7579172_5 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 1.771e-282 878.0
PYH3_k127_7579172_50 His Kinase A (phosphoacceptor) domain K02668,K10125 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 332.0
PYH3_k127_7579172_51 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000003,GO:0003006,GO:0003674,GO:0003824,GO:0004764,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0007275,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009790,GO:0009791,GO:0009793,GO:0009987,GO:0010154,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0022414,GO:0032501,GO:0032502,GO:0032787,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0046417,GO:0048316,GO:0048608,GO:0048731,GO:0048856,GO:0055114,GO:0061458,GO:0071704,GO:1901576,GO:1901615 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000118 309.0
PYH3_k127_7579172_52 Methylates ribosomal protein L11 K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 307.0
PYH3_k127_7579172_53 Peptidase family M23 K08259 - 3.4.24.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001855 302.0
PYH3_k127_7579172_54 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 299.0
PYH3_k127_7579172_55 Polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 298.0
PYH3_k127_7579172_56 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 287.0
PYH3_k127_7579172_57 FHA Domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002339 293.0
PYH3_k127_7579172_58 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002633 284.0
PYH3_k127_7579172_59 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003421 287.0
PYH3_k127_7579172_6 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 7.557e-278 864.0
PYH3_k127_7579172_60 Predicted integral membrane protein (DUF2189) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003502 280.0
PYH3_k127_7579172_61 PFAM Lytic transglycosylase catalytic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000354 254.0
PYH3_k127_7579172_62 PFAM Patatin K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002315 246.0
PYH3_k127_7579172_63 PFAM N-acetylmuramoyl-L-alanine amidase family 2 K03806 GO:0000270,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0008745,GO:0009056,GO:0009057,GO:0009253,GO:0009254,GO:0009392,GO:0016020,GO:0016787,GO:0016810,GO:0016811,GO:0019867,GO:0030203,GO:0043167,GO:0043169,GO:0043170,GO:0046872,GO:0046914,GO:0061783,GO:0071704,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000008731 239.0
PYH3_k127_7579172_64 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000002624 238.0
PYH3_k127_7579172_65 UPF0056 inner membrane protein K05595 - - 0.00000000000000000000000000000000000000000000000000000000000000003265 230.0
PYH3_k127_7579172_66 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000000000000000009157 218.0
PYH3_k127_7579172_67 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.00000000000000000000000000000000000000000000000000000000002264 216.0
PYH3_k127_7579172_68 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000004628 225.0
PYH3_k127_7579172_69 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.0000000000000000000000000000000000000000000000000000000009946 212.0
PYH3_k127_7579172_7 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 1.404e-264 822.0
PYH3_k127_7579172_70 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000000000000000000000000000001338 206.0
PYH3_k127_7579172_71 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.00000000000000000000000000000000000000000000000000008055 195.0
PYH3_k127_7579172_72 Belongs to the MraZ family K03925 - - 0.000000000000000000000000000000000000000000000000000114 189.0
PYH3_k127_7579172_73 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000001559 189.0
PYH3_k127_7579172_74 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.000000000000000000000000000000000000000000000001893 182.0
PYH3_k127_7579172_75 Transglycosylase SLT domain - - - 0.000000000000000000000000000000000000000000000005673 184.0
PYH3_k127_7579172_76 Esterase of the alpha-beta hydrolase superfamily K07001 - - 0.00000000000000000000000000000000000000000000001244 176.0
PYH3_k127_7579172_77 YbaK prolyl-tRNA synthetase associated - - - 0.000000000000000000000000000000000000000000104 166.0
PYH3_k127_7579172_78 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.0000000000000000000000000000000000000000082 155.0
PYH3_k127_7579172_79 YGGT family K02221 - - 0.0000000000000000000000000000000000000000491 158.0
PYH3_k127_7579172_8 PFAM Carbamoyl-phosphate synthase L chain, ATP binding domain, Biotin carboxylase C-terminal domain, Carbamoyl-phosphate synthase L chain, N-terminal domain K01961 GO:0003674,GO:0003824,GO:0004075,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010565,GO:0016053,GO:0016874,GO:0016879,GO:0019216,GO:0019217,GO:0019222,GO:0019752,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032787,GO:0042304,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0045717,GO:0045833,GO:0045922,GO:0046394,GO:0046890,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051055,GO:0062012,GO:0062014,GO:0065007,GO:0071704,GO:0072330,GO:0080090,GO:1901576 6.3.4.14,6.4.1.2 2.605e-254 789.0
PYH3_k127_7579172_80 mRNA catabolic process - - - 0.0000000000000000000000000000000000000007348 156.0
PYH3_k127_7579172_81 ribonuclease K01167 - 3.1.27.3 0.000000000000000000000000000000000000001837 151.0
PYH3_k127_7579172_82 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.00000000000000000000000000000000000006251 149.0
PYH3_k127_7579172_83 zinc-ribbon domain - - - 0.0000000000000000000000000000000000001401 155.0
PYH3_k127_7579172_84 cation diffusion facilitator family transporter - - - 0.0000000000000000000000000000000000002651 153.0
PYH3_k127_7579172_85 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000004352 138.0
PYH3_k127_7579172_86 Lysin motif - - - 0.000000000000000000000000000000001811 140.0
PYH3_k127_7579172_87 KTSC domain - - - 0.000000000000000000000000000001444 121.0
PYH3_k127_7579172_88 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000001171 119.0
PYH3_k127_7579172_89 Barstar (barnase inhibitor) - - - 0.0000000000000000000003212 100.0
PYH3_k127_7579172_9 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 5.493e-249 780.0
PYH3_k127_7579172_90 Histidine kinase-like ATPase domain - - - 0.000000000000000000006643 98.0
PYH3_k127_7579172_91 COGs COG3293 - - - 0.000000000000000001563 89.0
PYH3_k127_7579172_92 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.0000000000000001142 83.0
PYH3_k127_7579172_93 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 - - - 0.0000000000000003553 81.0
PYH3_k127_7579172_94 PFAM Sulfate transporter antisigma-factor antagonist STAS K04749,K06378 - - 0.0000000000000005129 81.0
PYH3_k127_7579172_95 Histone H1-like nucleoprotein HC2 K11275 - - 0.000000000001309 72.0
PYH3_k127_7579172_97 - K06950 - - 0.000000002453 63.0
PYH3_k127_7579172_98 membrane K06077 - - 0.000000003551 61.0
PYH3_k127_7579172_99 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.00000001162 60.0
PYH3_k127_7593767_0 Phosphotransferase enzyme family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001995 413.0
PYH3_k127_7593767_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004748 409.0
PYH3_k127_7593767_2 Hypothetical methyltransferase K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 398.0
PYH3_k127_7593767_3 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process - - - 0.000000000000000000000000000000003732 145.0
PYH3_k127_7596909_0 Branched-chain amino acid transport system / permease component K01995,K01998 - - 4.707e-260 814.0
PYH3_k127_7596909_1 PFAM D-galactarate dehydratase Altronate hydrolase domain protein K01685,K16846 - 4.2.1.7,4.4.1.24 5.016e-231 724.0
PYH3_k127_7596909_10 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K22229 - 1.1.1.215 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 344.0
PYH3_k127_7596909_11 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 293.0
PYH3_k127_7596909_12 PFAM regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000000000004514 239.0
PYH3_k127_7596909_13 Regulatory protein GntR HTH - - - 0.00000000000000000000000000000000000000000000000000000000000005372 222.0
PYH3_k127_7596909_14 Belongs to the 5'-nucleotidase family K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000009918 196.0
PYH3_k127_7596909_15 PFAM Tripartite ATP-independent periplasmic transporter, DctQ component - - - 0.00000000000000000000000000000000000000000000000000001312 194.0
PYH3_k127_7596909_16 Bacterial protein of unknown function (DUF882) - - - 0.00000000000000000000000000000000000003604 150.0
PYH3_k127_7596909_17 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000005051 90.0
PYH3_k127_7596909_18 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.0000000000000003546 79.0
PYH3_k127_7596909_2 TRAP C4-dicarboxylate transport system permease DctM subunit K11690 - - 1.241e-223 700.0
PYH3_k127_7596909_3 Periplasmic binding protein K01999 - - 1.001e-202 647.0
PYH3_k127_7596909_4 5'-nucleotidase, C-terminal domain K01119 - 3.1.3.6,3.1.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008079 488.0
PYH3_k127_7596909_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001693 447.0
PYH3_k127_7596909_6 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 430.0
PYH3_k127_7596909_7 Branched-chain amino acid transport system / permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000843 428.0
PYH3_k127_7596909_8 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004507 396.0
PYH3_k127_7596909_9 mannose-ethanolamine phosphotransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003678 408.0
PYH3_k127_7656849_0 PFAM AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 583.0
PYH3_k127_7656849_1 Putative sugar-binding N-terminal domain K21948 - 2.7.1.217 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004469 419.0
PYH3_k127_7656849_2 Class II Aldolase and Adducin N-terminal domain K22130 - 4.1.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007162 287.0
PYH3_k127_7656849_3 COG1179 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 K22132 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002865 276.0
PYH3_k127_7656849_4 Universal stress protein family - - - 0.000000000000000000000000000000000000000000000001231 177.0
PYH3_k127_7656849_5 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000003167 130.0
PYH3_k127_7656849_6 Hemerythrin HHE cation binding domain - - - 0.00000000000000001125 89.0
PYH3_k127_7656849_7 PFAM Hemerythrin HHE cation binding domain protein K07216 - - 0.000004384 54.0
PYH3_k127_7657429_0 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 590.0
PYH3_k127_7657429_1 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000000004478 137.0
PYH3_k127_7657429_2 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.0000000000000000000000006383 103.0
PYH3_k127_7663833_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K03520,K04108 - 1.2.5.3,1.3.7.9 2.808e-275 861.0
PYH3_k127_7663833_1 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 1.053e-215 677.0
PYH3_k127_7663833_10 Iron-sulfur cluster assembly protein - - - 0.0000000000000000000000000000000469 133.0
PYH3_k127_7663833_11 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000002261 108.0
PYH3_k127_7663833_12 ferredoxin - - - 0.00000000000009751 73.0
PYH3_k127_7663833_2 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 594.0
PYH3_k127_7663833_3 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 383.0
PYH3_k127_7663833_4 Vitamin k epoxide reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 368.0
PYH3_k127_7663833_5 CO dehydrogenase flavoprotein C-terminal domain K04109 - 1.3.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002133 355.0
PYH3_k127_7663833_6 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001778 315.0
PYH3_k127_7663833_7 Acetyltransferase (GNAT) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000009391 243.0
PYH3_k127_7663833_8 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000006542 197.0
PYH3_k127_7663833_9 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000001298 146.0
PYH3_k127_766447_0 Aldehyde oxidase and xanthine dehydrogenase K03520 - 1.2.5.3 0.0 1248.0
PYH3_k127_766447_1 Quinohemoprotein amine dehydrogenase, alpha subunit domain II - - - 5.523e-195 621.0
PYH3_k127_766447_10 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000008275 238.0
PYH3_k127_766447_11 Quinohemoprotein amine dehydrogenase, gamma subunit - - - 0.000000000000000000000000000000000000000000000000004406 193.0
PYH3_k127_766447_12 Cytochrome B561 K12262 - - 0.00000000000000000000000000000000000000000007643 167.0
PYH3_k127_766447_2 ABC transporter transmembrane region - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 608.0
PYH3_k127_766447_3 Radical SAM superfamily K06871 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 522.0
PYH3_k127_766447_4 Peptidase family U32 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 407.0
PYH3_k127_766447_5 Quinohemoprotein amine dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008645 399.0
PYH3_k127_766447_6 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004616 331.0
PYH3_k127_766447_7 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000002597 269.0
PYH3_k127_766447_8 peptidase U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006797 259.0
PYH3_k127_766447_9 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000003639 243.0
PYH3_k127_7678282_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1429.0
PYH3_k127_7678282_1 Peptidase family M3 K01414 - 3.4.24.70 5.331e-281 887.0
PYH3_k127_7678282_10 PFAM Glutaredoxin - - - 0.0000000000000000000000000000000002853 142.0
PYH3_k127_7678282_2 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 3.579e-267 837.0
PYH3_k127_7678282_3 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00627 - 2.3.1.12 2.408e-209 665.0
PYH3_k127_7678282_4 PFAM ATP-binding region, ATPase domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007698 446.0
PYH3_k127_7678282_5 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006271 387.0
PYH3_k127_7678282_6 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 362.0
PYH3_k127_7678282_7 Proteasome subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002385 281.0
PYH3_k127_7678282_8 - - - - 0.000000000000000000000000000000000000000007163 163.0
PYH3_k127_7678282_9 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.0000000000000000000000000000000000001947 151.0
PYH3_k127_769065_0 Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. PhnW subfamily K03430 - 2.6.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002485 589.0
PYH3_k127_769065_1 Haloacid dehalogenase-like hydrolase K05306 - 3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000009661 259.0
PYH3_k127_7691310_0 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000001968 229.0
PYH3_k127_7691310_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.000000000000000000003175 93.0
PYH3_k127_7691310_2 Psort location OuterMembrane, score 9.49 K09800 - - 0.00000000000004047 73.0
PYH3_k127_7696073_0 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000087 472.0
PYH3_k127_7696073_1 PFAM Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001191 421.0
PYH3_k127_7696073_10 amine dehydrogenase activity - - - 0.00000000000000000001436 92.0
PYH3_k127_7696073_11 Phosphopantetheine attachment site - - - 0.00000000000000000003431 102.0
PYH3_k127_7696073_12 NADH pyrophosphatase K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.000000008318 59.0
PYH3_k127_7696073_13 Cytochrome c - - - 0.00000006263 54.0
PYH3_k127_7696073_14 nadh pyrophosphatase K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0033554,GO:0034641,GO:0035529,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0046872,GO:0046914,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 3.6.1.22 0.00000006877 57.0
PYH3_k127_7696073_15 Cytochrome c - - - 0.0000005936 57.0
PYH3_k127_7696073_16 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.000001378 53.0
PYH3_k127_7696073_17 phosphocarrier, HPr family K11189 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00001405 51.0
PYH3_k127_7696073_18 Uncharacterised protein family (UPF0093) - - - 0.00007976 50.0
PYH3_k127_7696073_2 LysR substrate binding domain K03717 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 393.0
PYH3_k127_7696073_3 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002556 396.0
PYH3_k127_7696073_4 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 367.0
PYH3_k127_7696073_5 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 GO:0003674,GO:0003824,GO:0004551,GO:0005488,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0035529,GO:0043167,GO:0043169,GO:0046872,GO:0046914 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006986 346.0
PYH3_k127_7696073_6 YaeQ family - - - 0.0000000000000000000000000000000000000000000000000000000000000007568 223.0
PYH3_k127_7696073_7 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000002338 197.0
PYH3_k127_7696073_8 Plasmid stabilization system K19092 - - 0.00000000000000000000000000165 115.0
PYH3_k127_7696073_9 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.000000000000000000001102 96.0
PYH3_k127_770412_0 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002517 560.0
PYH3_k127_770412_1 TIGRFAM cytochrome C family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000241 421.0
PYH3_k127_770412_2 (GMC) oxidoreductase K00108 - 1.1.99.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004608 275.0
PYH3_k127_770412_3 Thioesterase - - - 0.0000000000000000000000000000000000000001122 151.0
PYH3_k127_770412_4 PFAM CHRD domain containing protein - - - 0.00000000000000001038 91.0
PYH3_k127_7806735_0 COG1960 Acyl-CoA dehydrogenases - - - 2.129e-198 623.0
PYH3_k127_7806735_1 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 431.0
PYH3_k127_7806735_2 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000000000001344 213.0
PYH3_k127_7806735_3 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000001983 121.0
PYH3_k127_7834937_0 Acyl-CoA dehydrogenase, middle domain - - - 1.552e-213 668.0
PYH3_k127_7834937_1 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006135 590.0
PYH3_k127_7834937_10 peptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007839 370.0
PYH3_k127_7834937_11 peptidase S1 and S6, chymotrypsin Hap - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001966 331.0
PYH3_k127_7834937_12 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 303.0
PYH3_k127_7834937_13 LemA family K03744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 298.0
PYH3_k127_7834937_14 Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation K07130 GO:0003674,GO:0003824,GO:0004061,GO:0005488,GO:0006082,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009056,GO:0009063,GO:0009072,GO:0009074,GO:0009308,GO:0009310,GO:0009987,GO:0016054,GO:0016787,GO:0016810,GO:0016811,GO:0019439,GO:0019441,GO:0019752,GO:0032787,GO:0034641,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043167,GO:0043169,GO:0043420,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044282,GO:0046218,GO:0046395,GO:0046483,GO:0046700,GO:0046872,GO:0046914,GO:0070189,GO:0071704,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 3.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007676 293.0
PYH3_k127_7834937_15 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007059 242.0
PYH3_k127_7834937_16 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000002499 218.0
PYH3_k127_7834937_17 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000001613 211.0
PYH3_k127_7834937_18 endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000000000000000000000000009851 179.0
PYH3_k127_7834937_19 PFAM flavin reductase domain protein, FMN-binding - - - 0.000000000000000000000000000000000000000000000001371 179.0
PYH3_k127_7834937_2 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 541.0
PYH3_k127_7834937_20 - - - - 0.000000000000000000000000000000000000002862 151.0
PYH3_k127_7834937_21 Protein of unknown function (DUF1778) - - - 0.0000000000000000000000000000000000000341 144.0
PYH3_k127_7834937_22 Plasmid stabilization system K19092 - - 0.00000000000000000000000000000000000004428 145.0
PYH3_k127_7834937_23 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000003833 153.0
PYH3_k127_7834937_24 GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000001328 130.0
PYH3_k127_7834937_25 GYD domain - - - 0.00000000000000000000000000001804 120.0
PYH3_k127_7834937_26 Thioesterase-like superfamily K01075 - 3.1.2.23 0.000000000000000000000000007517 114.0
PYH3_k127_7834937_27 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.00000000000000000000001069 104.0
PYH3_k127_7834937_28 Domain of unknown function (DUF1992) - - - 0.0000000000000000000009623 99.0
PYH3_k127_7834937_29 - - - - 0.000000000000000000002913 102.0
PYH3_k127_7834937_3 ATPase family associated with various cellular activities (AAA) K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002682 538.0
PYH3_k127_7834937_30 - - - - 0.0000000000000001657 83.0
PYH3_k127_7834937_31 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.0000004155 54.0
PYH3_k127_7834937_32 Protein of unknown function (DUF3617) - - - 0.0001163 51.0
PYH3_k127_7834937_34 Tripartite tricarboxylate transporter family receptor - - - 0.000215 44.0
PYH3_k127_7834937_4 Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively K01556 - 3.7.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003064 510.0
PYH3_k127_7834937_5 von Willebrand factor, type A K07114 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004704 446.0
PYH3_k127_7834937_6 von Willebrand factor (vWF) type A domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 413.0
PYH3_k127_7834937_7 Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety K00453 GO:0003674,GO:0003824,GO:0004833,GO:0005488,GO:0006082,GO:0006139,GO:0006520,GO:0006568,GO:0006569,GO:0006576,GO:0006586,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009072,GO:0009074,GO:0009108,GO:0009117,GO:0009165,GO:0009308,GO:0009310,GO:0009435,GO:0009987,GO:0016043,GO:0016053,GO:0016054,GO:0016491,GO:0016701,GO:0016702,GO:0017144,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019439,GO:0019441,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0020037,GO:0022607,GO:0034641,GO:0034654,GO:0042180,GO:0042402,GO:0042430,GO:0042436,GO:0042537,GO:0043436,GO:0043648,GO:0043650,GO:0043933,GO:0044085,GO:0044106,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0046218,GO:0046394,GO:0046395,GO:0046483,GO:0046496,GO:0046700,GO:0046874,GO:0046906,GO:0048037,GO:0051186,GO:0051188,GO:0051213,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055086,GO:0055114,GO:0065003,GO:0070189,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606 1.13.11.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 407.0
PYH3_k127_7834937_8 COG0665 Glycine D-amino acid oxidases (deaminating) K19746 - 1.4.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 388.0
PYH3_k127_7834937_9 domain, Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002678 387.0
PYH3_k127_7860457_0 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008517 286.0
PYH3_k127_7860457_1 Domain of unknown function (DUF309) - - - 0.0000000000000000000000000000000000000000000000000000000000000000003106 231.0
PYH3_k127_7860457_2 Histidine biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000000000103 223.0
PYH3_k127_7860457_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS - - - 0.00000000000000006773 87.0
PYH3_k127_7867267_0 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002955 355.0
PYH3_k127_7867267_1 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002832 348.0
PYH3_k127_7867267_2 ABC-type phosphate phosphonate transport system permease component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 311.0
PYH3_k127_7893346_0 L-carnitine dehydratase bile acid-inducible protein F - - - 2.437e-201 637.0
PYH3_k127_7893346_1 PFAM conserved K07795 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003554 340.0
PYH3_k127_7893346_2 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000002325 100.0
PYH3_k127_7893346_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000238 88.0
PYH3_k127_7893346_4 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000000005718 89.0
PYH3_k127_791057_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 0.0 1011.0
PYH3_k127_791057_1 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 514.0
PYH3_k127_791057_2 Glucose / Sorbosone dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007226 452.0
PYH3_k127_791057_3 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003951 432.0
PYH3_k127_791057_4 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001957 425.0
PYH3_k127_791057_5 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 424.0
PYH3_k127_791057_6 HMGL-like K01640 GO:0000287,GO:0003674,GO:0003824,GO:0004419,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005777,GO:0005782,GO:0005829,GO:0006082,GO:0006091,GO:0006520,GO:0006551,GO:0006552,GO:0006605,GO:0006625,GO:0006629,GO:0006807,GO:0006810,GO:0006886,GO:0006996,GO:0007031,GO:0008104,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0015031,GO:0015833,GO:0016043,GO:0016054,GO:0016829,GO:0016830,GO:0016833,GO:0017144,GO:0019752,GO:0022607,GO:0030145,GO:0031907,GO:0031974,GO:0033036,GO:0033365,GO:0034613,GO:0042579,GO:0042802,GO:0042803,GO:0042886,GO:0043167,GO:0043169,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0043574,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044438,GO:0044439,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0046395,GO:0046872,GO:0046907,GO:0046914,GO:0046950,GO:0046951,GO:0046983,GO:0051179,GO:0051234,GO:0051259,GO:0051262,GO:0051641,GO:0051649,GO:0065003,GO:0070013,GO:0070727,GO:0071702,GO:0071704,GO:0071705,GO:0071840,GO:0072594,GO:0072662,GO:0072663,GO:1901564,GO:1901565,GO:1901568,GO:1901570,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1902224 4.1.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 417.0
PYH3_k127_791057_7 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001857 336.0
PYH3_k127_791057_8 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 324.0
PYH3_k127_791057_9 CDP-alcohol phosphatidyltransferase - - - 0.00000000000000000000000000000000001999 142.0
PYH3_k127_7920757_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.289e-266 830.0
PYH3_k127_7920757_1 Cytochrome b(N-terminal)/b6/petB - - - 3.936e-231 732.0
PYH3_k127_7920757_2 NnrS protein K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003324 319.0
PYH3_k127_7920757_3 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 290.0
PYH3_k127_7920757_4 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 289.0
PYH3_k127_7920757_5 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000000000000000002995 180.0
PYH3_k127_7920757_6 Invasion gene expression up-regulator SirB - - - 0.00000000000000000000000000007933 119.0
PYH3_k127_7920757_7 - - - - 0.000000000009105 68.0
PYH3_k127_7947135_0 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.000000000000000000000000000000000000000000000000000000000000000000000000001586 261.0
PYH3_k127_7947135_1 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000002819 190.0
PYH3_k127_7947135_2 Multidrug Resistance protein K11741 - - 0.000000000000000000000000000000000000000000000117 171.0
PYH3_k127_7947135_3 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000002035 133.0
PYH3_k127_795_1 PFAM Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000006798 208.0
PYH3_k127_795_2 - - - - 0.0000005972 53.0
PYH3_k127_8067552_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1299.0
PYH3_k127_8067552_1 Belongs to the ClpA ClpB family K03694 - - 0.0 1262.0
PYH3_k127_8067552_10 fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 506.0
PYH3_k127_8067552_11 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 490.0
PYH3_k127_8067552_12 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 481.0
PYH3_k127_8067552_13 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004249 463.0
PYH3_k127_8067552_14 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002372 405.0
PYH3_k127_8067552_15 Tyrosine recombinase XerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001035 394.0
PYH3_k127_8067552_16 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009695 377.0
PYH3_k127_8067552_17 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K03601,K04564 GO:0000302,GO:0000303,GO:0000305,GO:0003674,GO:0003824,GO:0004784,GO:0006801,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0010035,GO:0016209,GO:0016491,GO:0016721,GO:0019430,GO:0033554,GO:0034599,GO:0034614,GO:0042221,GO:0044237,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071450,GO:0071451,GO:0072593,GO:0097237,GO:0098754,GO:0098869,GO:1901700,GO:1901701,GO:1990748 1.15.1.1,3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 363.0
PYH3_k127_8067552_18 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 362.0
PYH3_k127_8067552_19 mechanosensitive K05802 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002085 349.0
PYH3_k127_8067552_2 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 3.197e-265 836.0
PYH3_k127_8067552_20 Belongs to the UPF0758 family K03630 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 289.0
PYH3_k127_8067552_21 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily K03976 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003957 240.0
PYH3_k127_8067552_22 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000005935 241.0
PYH3_k127_8067552_23 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000001885 235.0
PYH3_k127_8067552_24 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000002289 233.0
PYH3_k127_8067552_25 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000000000000000000000000000000000000000000000000000001038 224.0
PYH3_k127_8067552_26 CoA-binding protein K06929 - - 0.0000000000000000000000000000000000000000000000000000000000236 211.0
PYH3_k127_8067552_27 PFAM EAL domain protein - - - 0.000000000000000000000000000000000000000000000000000002451 216.0
PYH3_k127_8067552_28 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000000292 193.0
PYH3_k127_8067552_29 Chalcone isomerase-like - - - 0.0000000000000000000000000000000000000000000000000001383 193.0
PYH3_k127_8067552_3 Converts isocitrate to alpha ketoglutarate K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 5.822e-239 743.0
PYH3_k127_8067552_30 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000001439 191.0
PYH3_k127_8067552_31 PAC sensor-containing diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000402 190.0
PYH3_k127_8067552_32 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000008123 169.0
PYH3_k127_8067552_33 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000001736 169.0
PYH3_k127_8067552_34 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.000000000000000000000000000000000000000001395 157.0
PYH3_k127_8067552_35 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000000000003375 139.0
PYH3_k127_8067552_36 Cold shock protein K03704 - - 0.0000000000000000000000000000000002042 134.0
PYH3_k127_8067552_37 Ribosomal protein S21 K02970 - - 0.00000000000000000000000000000004647 128.0
PYH3_k127_8067552_38 - - - - 0.000000000000000000000000000002125 128.0
PYH3_k127_8067552_39 Peptidyl-prolyl cis-trans K03774 - 5.2.1.8 0.00000000000000000000000000001305 123.0
PYH3_k127_8067552_4 DNA polymerase K00986 - 2.7.7.49 2.899e-225 707.0
PYH3_k127_8067552_40 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000002995 101.0
PYH3_k127_8067552_41 cytochrome - - - 0.000000000000000000002817 98.0
PYH3_k127_8067552_5 TIGRFAM O-acetylhomoserine O-acetylserine sulfhydrylase K01740 - 2.5.1.49 1.342e-203 641.0
PYH3_k127_8067552_6 DEAD/DEAH box helicase K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 535.0
PYH3_k127_8067552_7 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 532.0
PYH3_k127_8067552_8 Pfam:Nol1_Nop2_Fmu K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000821 512.0
PYH3_k127_8067552_9 sulfide dehydrogenase K05301 - 1.8.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001464 510.0
PYH3_k127_808275_0 oxidoreductase K04090 - 1.2.7.8 0.0 1458.0
PYH3_k127_808275_1 A predicted alpha-helical domain with a conserved ER motif. - - - 9.868e-297 932.0
PYH3_k127_808275_10 Universal stress protein family - - - 0.0000000000000000000000000000000000000000000000000000000471 211.0
PYH3_k127_808275_11 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000005297 158.0
PYH3_k127_808275_2 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 2.981e-257 812.0
PYH3_k127_808275_3 KR domain K00019 - 1.1.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001302 372.0
PYH3_k127_808275_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004737 366.0
PYH3_k127_808275_5 PFAM transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 350.0
PYH3_k127_808275_6 transglutaminase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004024 333.0
PYH3_k127_808275_7 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004908 290.0
PYH3_k127_808275_8 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003882 277.0
PYH3_k127_808275_9 NADPH-dependent FMN reductase - - - 0.000000000000000000000000000000000000000000000000000000000002194 214.0
PYH3_k127_8135791_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1016.0
PYH3_k127_8135791_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004345 571.0
PYH3_k127_8135791_2 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001327 223.0
PYH3_k127_8135791_3 Protein of unknown function (DUF3579) - - - 0.000000000000000000000000000000000001925 143.0
PYH3_k127_8135791_4 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000000000000000002851 108.0
PYH3_k127_8146875_0 Acyl-CoA dehydrogenase, C-terminal domain K00253 - 1.3.8.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001133 547.0
PYH3_k127_8146875_1 acetyl-coa acetyltransferase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 338.0
PYH3_k127_8148764_0 FtsX-like permease family K02004 - - 1.578e-278 879.0
PYH3_k127_8148764_1 Tripartite tricarboxylate transporter TctA family - - - 9.078e-253 788.0
PYH3_k127_8148764_10 Bacterial-like globin K06886 - - 0.00000000000000000000000000000000000000000000000000005553 194.0
PYH3_k127_8148764_11 - - - - 0.00000000000000000000000000000000000000000002655 167.0
PYH3_k127_8148764_12 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000001285 161.0
PYH3_k127_8148764_13 Elements of external origin K07494 - - 0.00000000000000000000000000000000001874 136.0
PYH3_k127_8148764_14 protein conserved in bacteria K09966 - - 0.000000000000000000000001933 107.0
PYH3_k127_8148764_15 PIN domain - - - 0.0000000000000000000008544 102.0
PYH3_k127_8148764_16 3' exoribonuclease, RNase T-like - - - 0.0000333 57.0
PYH3_k127_8148764_2 Aminotransferase K14287 - 2.6.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007695 505.0
PYH3_k127_8148764_3 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 484.0
PYH3_k127_8148764_4 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008446 470.0
PYH3_k127_8148764_5 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 463.0
PYH3_k127_8148764_6 DNA recombination protein, rmuC K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003577 462.0
PYH3_k127_8148764_7 major facilitator superfamily K03446 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002758 339.0
PYH3_k127_8148764_8 Belongs to the ompA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004794 262.0
PYH3_k127_8148764_9 PFAM secretion protein HlyD family protein K03543 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002452 253.0
PYH3_k127_816449_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001367 429.0
PYH3_k127_816449_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.00000000000000000000000000000000000007335 157.0
PYH3_k127_816449_2 OsmC-like protein - - - 0.0000000000000000000000000000000000938 138.0
PYH3_k127_816449_3 thiamine biosynthesis protein ThiS K03154 - - 0.000000000002308 66.0
PYH3_k127_820182_0 FAD dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003259 423.0
PYH3_k127_820182_1 BFD-like [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001964 394.0
PYH3_k127_820182_2 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000001002 127.0
PYH3_k127_820182_3 ABC transporter permease K02053 - - 0.000000000000000000002035 94.0
PYH3_k127_8205542_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 520.0
PYH3_k127_8205542_1 Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000003885 119.0
PYH3_k127_8205542_2 Protein of unknown function (DUF2490) - - - 0.00000009158 59.0
PYH3_k127_8227014_0 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006287 483.0
PYH3_k127_8227014_1 Saccharopine dehydrogenase - - - 0.000000000000000000000000000000000000000000002002 168.0
PYH3_k127_8227014_2 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.000000000000000000000000001839 115.0
PYH3_k127_8227014_3 Histidine kinase - - - 0.000000000000000000004341 95.0
PYH3_k127_8267497_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 GO:0003674,GO:0003824,GO:0004478,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0016740,GO:0016765,GO:0044424,GO:0044444,GO:0044464 2.5.1.6 1.296e-208 653.0
PYH3_k127_8267497_1 Predicted periplasmic protein (DUF2092) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 385.0
PYH3_k127_8267497_2 - - - - 0.0000000000000000000000000000000000000000000000000000000145 201.0
PYH3_k127_8267497_3 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000004435 127.0
PYH3_k127_8267497_4 HupE / UreJ protein - - - 0.000003043 49.0
PYH3_k127_8281684_0 synthetase K01907 - 6.2.1.16 1.101e-285 892.0
PYH3_k127_8281684_1 PFAM MmgE PrpD family protein - - - 7.074e-231 722.0
PYH3_k127_8281684_10 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 373.0
PYH3_k127_8281684_11 Kelch - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008038 258.0
PYH3_k127_8281684_12 Protein of unknown function (DUF3014) - - - 0.0000000000000000000000000000000000000000000000000000000000001573 224.0
PYH3_k127_8281684_13 BFD-like [2Fe-2S] binding domain - - - 0.00000000000000000000000000000000000000000000000000000005749 198.0
PYH3_k127_8281684_14 - - - - 0.00000000000000000000000000000000000000000008344 168.0
PYH3_k127_8281684_15 transcriptional regulator - - - 0.000000000000000000000000000000000001039 151.0
PYH3_k127_8281684_16 Glycine-zipper domain - - - 0.00000000000000000000000000000000001811 143.0
PYH3_k127_8281684_17 HicA toxin of bacterial toxin-antitoxin, - - - 0.000000000000000000000000000004861 122.0
PYH3_k127_8281684_18 Cytochrome c K17223 - - 0.0000000000000000000000004644 111.0
PYH3_k127_8281684_19 - - - - 0.000000000000000000000769 100.0
PYH3_k127_8281684_2 ABC transporter C-terminal domain K15738 - - 3.691e-230 729.0
PYH3_k127_8281684_20 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.000000000000518 72.0
PYH3_k127_8281684_21 Bacteriocin-protection, YdeI or OmpD-Associated - - - 0.0003683 45.0
PYH3_k127_8281684_3 Ammonium Transporter Family K03320,K06580 - - 1.048e-219 686.0
PYH3_k127_8281684_4 FAD dependent oxidoreductase K00303 - 1.5.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006945 503.0
PYH3_k127_8281684_5 Thioredoxin-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008094 481.0
PYH3_k127_8281684_6 Fumarylacetoacetate (FAA) hydrolase family K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 445.0
PYH3_k127_8281684_7 Sulfatase-modifying factor enzyme 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 434.0
PYH3_k127_8281684_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 430.0
PYH3_k127_8281684_9 ABC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003062 407.0
PYH3_k127_8313872_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 6.859e-303 933.0
PYH3_k127_8313872_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000934 539.0
PYH3_k127_8313872_2 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006795 372.0
PYH3_k127_8313872_3 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 297.0
PYH3_k127_8313872_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000002461 234.0
PYH3_k127_8313872_5 ABC transporter - - - 0.000000000000000000000000000000000000000000000000000000001006 218.0
PYH3_k127_8313872_6 PFAM thiamineS protein - - - 0.000000000000000000000002801 104.0
PYH3_k127_8313872_7 - - - - 0.000000000003674 70.0
PYH3_k127_8317293_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 5.848e-306 952.0
PYH3_k127_8317293_1 Belongs to the binding-protein-dependent transport system permease family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 520.0
PYH3_k127_8317293_10 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000001861 189.0
PYH3_k127_8317293_11 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000009813 171.0
PYH3_k127_8317293_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000001426 108.0
PYH3_k127_8317293_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02051 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001767 484.0
PYH3_k127_8317293_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004915 458.0
PYH3_k127_8317293_4 PFAM ABC transporter related K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 446.0
PYH3_k127_8317293_5 PFAM aldo keto reductase - GO:0003674,GO:0003824,GO:0006081,GO:0008150,GO:0008152,GO:0009056,GO:0009438,GO:0009987,GO:0016491,GO:0042180,GO:0042182,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046185,GO:0051596,GO:0055114,GO:0071704,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 351.0
PYH3_k127_8317293_6 PFAM binding-protein-dependent transport systems inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003035 339.0
PYH3_k127_8317293_7 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 289.0
PYH3_k127_8317293_8 ABC-type nitrate sulfonate bicarbonate transport system ATPase component K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000155 278.0
PYH3_k127_8317293_9 Major Facilitator - - - 0.00000000000000000000000000000000000000000000000000000000007467 205.0
PYH3_k127_8327236_0 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004529 404.0
PYH3_k127_8327236_1 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000005994 217.0
PYH3_k127_8327236_2 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000136 195.0
PYH3_k127_8327236_3 Protein of unknown function (DUF3302) - - - 0.000000000000000000000000000000000000006161 153.0
PYH3_k127_8327236_4 Glycosyl hydrolase family 63 C-terminal domain - - - 0.0000000000000000000000001565 108.0
PYH3_k127_83706_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 447.0
PYH3_k127_83706_1 haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 319.0
PYH3_k127_83706_2 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.000000000000000000000000000000000004536 141.0
PYH3_k127_83706_3 PFAM cytochrome c - - - 0.00000000000000000000000000001742 124.0
PYH3_k127_837162_0 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 563.0
PYH3_k127_837162_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 483.0
PYH3_k127_837162_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002573 244.0
PYH3_k127_837162_3 COG0154 Asp-tRNAAsn Glu-tRNAGln amidotransferase A subunit and related amidases - - - 0.0000000000000000000000000001883 117.0
PYH3_k127_837162_4 YceI-like domain - - - 0.000000000000007136 74.0
PYH3_k127_83763_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 484.0
PYH3_k127_83763_1 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008911 305.0
PYH3_k127_83763_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000004463 224.0
PYH3_k127_83763_3 Cytochrome c mono- and diheme variants - - - 0.0000000000000000000000000000000000000000000000000003744 189.0
PYH3_k127_83763_4 Thioesterase K18700 - 3.1.2.29 0.0000000000000000000000000000000003372 135.0
PYH3_k127_83763_5 Malate/L-lactate dehydrogenase K16844 - 1.1.1.338 0.00000000000000000000000000005979 117.0
PYH3_k127_83763_6 pyridoxamine 5-phosphate - - - 0.0000000000000000000000000001331 121.0
PYH3_k127_8402129_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1309.0
PYH3_k127_8402129_1 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1283.0
PYH3_k127_8402129_10 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 415.0
PYH3_k127_8402129_11 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 393.0
PYH3_k127_8402129_12 Bacterial regulatory proteins, crp family K01420 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004438 355.0
PYH3_k127_8402129_13 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008895 358.0
PYH3_k127_8402129_14 Cytochrome C oxidase, mono-heme subunit/FixO K00405 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 331.0
PYH3_k127_8402129_15 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005745 295.0
PYH3_k127_8402129_16 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002064 267.0
PYH3_k127_8402129_17 sister chromatid segregation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002091 273.0
PYH3_k127_8402129_18 Belongs to the MenA family. Type 1 subfamily K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000001265 261.0
PYH3_k127_8402129_19 NUDIX domain K03426 - 3.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000005548 223.0
PYH3_k127_8402129_2 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.317e-268 831.0
PYH3_k127_8402129_20 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000000000000000000000000000000000000000000000000002906 223.0
PYH3_k127_8402129_21 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000002068 188.0
PYH3_k127_8402129_22 Haem-degrading - - - 0.000000000000000000000000000000000000000000000000002546 187.0
PYH3_k127_8402129_23 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000818 178.0
PYH3_k127_8402129_24 Acetyltransferase (GNAT) domain K03790 - 2.3.1.128 0.00000000000000000000000000000000000000000000006747 175.0
PYH3_k127_8402129_25 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.0000000000000000000000000000000000000000000009195 174.0
PYH3_k127_8402129_26 Acetyltransferase (GNAT) domain K03825 - - 0.00000000000000000000000000000000000000000006932 166.0
PYH3_k127_8402129_27 - - - - 0.000000000000000000000000000000000000000002177 159.0
PYH3_k127_8402129_28 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000001696 152.0
PYH3_k127_8402129_29 Belongs to the sulfur carrier protein TusA family K04085 - - 0.0000000000000000000000000000001016 124.0
PYH3_k127_8402129_3 Tripartite tricarboxylate transporter TctA family K07793 - - 1.982e-244 762.0
PYH3_k127_8402129_30 - - - - 0.0000000000000000000000000007302 116.0
PYH3_k127_8402129_31 FixH family K09926 - - 0.000000000000000000000000007601 117.0
PYH3_k127_8402129_32 Belongs to the acylphosphatase family K01512 - 3.6.1.7 0.0000000000000000000005397 98.0
PYH3_k127_8402129_33 cellulase activity - - - 0.00000000000000000003907 105.0
PYH3_k127_8402129_34 Cbb3-type cytochrome oxidase K00407 - - 0.000000000000002591 76.0
PYH3_k127_8402129_35 cytochrome oxidase maturation protein cbb3-type - - - 0.000000008964 59.0
PYH3_k127_8402129_4 gamma-glutamyltransferase K00681 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006082,GO:0006508,GO:0006520,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0008242,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0019538,GO:0019752,GO:0030288,GO:0030313,GO:0031975,GO:0034722,GO:0036374,GO:0042597,GO:0043094,GO:0043102,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070011,GO:0071704,GO:0097264,GO:0140096,GO:1901564,GO:1901566,GO:1901576 2.3.2.2,3.4.19.13 1.095e-219 694.0
PYH3_k127_8402129_5 Domain of unknown function (DUF5117) - - - 3.634e-210 687.0
PYH3_k127_8402129_6 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001202 594.0
PYH3_k127_8402129_7 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009587 586.0
PYH3_k127_8402129_8 cytochrome C oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004274 585.0
PYH3_k127_8402129_9 Heavy-metal-associated domain K01533 - 3.6.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003741 499.0
PYH3_k127_8439959_0 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 498.0
PYH3_k127_8439959_1 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000936 483.0
PYH3_k127_8439959_2 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 374.0
PYH3_k127_8439959_3 Methylmalonyl-CoA mutase large subunit K01847 - 5.4.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001554 354.0
PYH3_k127_8439959_4 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 343.0
PYH3_k127_8439959_5 RmlD substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000337 334.0
PYH3_k127_8439959_6 Transcriptional regulator K07734 - - 0.00000000000000000000000000000000000000000000005416 184.0
PYH3_k127_8439959_7 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000009931 158.0
PYH3_k127_8534727_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 5.4e-323 995.0
PYH3_k127_8534727_1 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 1.97e-257 800.0
PYH3_k127_8534727_10 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006776 309.0
PYH3_k127_8534727_11 negative regulator of sigma E activity K03598 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007043 272.0
PYH3_k127_8534727_12 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000009977 258.0
PYH3_k127_8534727_13 Uroporphyrin-iii c tetrapyrrole (Corrin porphyrin) methyltransferase K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000000000000000000000009387 231.0
PYH3_k127_8534727_14 Maf-like protein K06287 - - 0.000000000000000000000000000000000000000000000000000000000000003024 222.0
PYH3_k127_8534727_15 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000006559 181.0
PYH3_k127_8534727_16 Rieske [2Fe-2S] domain - - - 0.0000000000000000000000000000000000000001299 156.0
PYH3_k127_8534727_17 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000000000003012 132.0
PYH3_k127_8534727_18 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.000000000000000000000000005035 112.0
PYH3_k127_8534727_19 Uncharacterized ACR, COG1399 K07040 - - 0.00000000000000001078 89.0
PYH3_k127_8534727_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 4.665e-210 659.0
PYH3_k127_8534727_20 Domain of unknown function (DUF4845) - - - 0.000000000000001503 83.0
PYH3_k127_8534727_21 Anti sigma-E protein RseA K03597 - - 0.000000001019 67.0
PYH3_k127_8534727_3 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004382 556.0
PYH3_k127_8534727_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009561 447.0
PYH3_k127_8534727_5 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 447.0
PYH3_k127_8534727_6 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006982 400.0
PYH3_k127_8534727_7 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005951 377.0
PYH3_k127_8534727_8 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 367.0
PYH3_k127_8534727_9 reductase K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009725 341.0
PYH3_k127_8597327_0 Evidence Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002603 357.0
PYH3_k127_8597327_1 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003058 299.0
PYH3_k127_8597327_2 Binding-protein-dependent transport system inner membrane component K02042 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 301.0
PYH3_k127_8597327_3 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.0000000000000000000000000000000000000000000000000000001652 212.0
PYH3_k127_8597327_4 PFAM cytoplasmic chaperone TorD family protein - - - 0.00000000000000000000000000000009928 141.0
PYH3_k127_8597327_5 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.000000003673 57.0
PYH3_k127_8651322_0 GntP family permease - - - 2.601e-212 668.0
PYH3_k127_8651322_1 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007862 493.0
PYH3_k127_8651322_2 Phospholipase_D-nuclease N-terminal - - - 0.000000000000000000000000000000000000000000000000005007 185.0
PYH3_k127_8651322_3 Elements of external origin K07497 - - 0.000000000000000000000000000000000000000001211 161.0
PYH3_k127_8651322_4 - - - - 0.0000000000000005123 80.0
PYH3_k127_8684695_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1238.0
PYH3_k127_8684695_1 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002757 606.0
PYH3_k127_8684695_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007058 469.0
PYH3_k127_8684695_3 ROK family K00845,K00847 - 2.7.1.2,2.7.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 367.0
PYH3_k127_8684695_4 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006639 335.0
PYH3_k127_8684695_6 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.0000000000000000000000000002367 117.0
PYH3_k127_8684695_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000000002548 73.0
PYH3_k127_8684695_8 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000003265 66.0
PYH3_k127_8684695_9 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000351 61.0
PYH3_k127_8685806_0 Binding-protein-dependent transport system inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007885 391.0
PYH3_k127_8685806_1 Binding-protein-dependent transport system inner membrane component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005269 373.0
PYH3_k127_8685806_2 Bacterial regulatory proteins, lacI family K02529 - - 0.00000000000000000000000000000000000000000000000000004753 192.0
PYH3_k127_8702155_0 Phage integrase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 341.0
PYH3_k127_8702155_1 Glutathione S-transferase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000005422 240.0
PYH3_k127_8702155_2 Bacterial antitoxin of ParD toxin-antitoxin type II system and RHH K07746 - - 0.00000003969 56.0
PYH3_k127_8707359_0 Domain of Unknown Function (DUF748) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001929 593.0
PYH3_k127_8720460_0 DDE superfamily endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 395.0
PYH3_k127_8720460_1 PFAM Peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004964 313.0
PYH3_k127_8720460_2 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000002128 222.0
PYH3_k127_8720460_3 Protein of unknown function (DUF2846) - - - 0.000000000000000000001389 99.0
PYH3_k127_8720460_4 Domain of unknown function (DUF4437) - - - 0.00000000006121 68.0
PYH3_k127_8720460_5 transporter arsB - - - 0.0002295 48.0
PYH3_k127_8746330_0 Phosphopantetheine attachment site - - - 5.354e-270 861.0
PYH3_k127_8746330_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 8.635e-269 837.0
PYH3_k127_8746330_10 coenzyme F390 synthetase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 371.0
PYH3_k127_8746330_11 Putative aminopeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000797 362.0
PYH3_k127_8746330_12 Putative heavy-metal chelation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000456 345.0
PYH3_k127_8746330_13 AAA domain K07028 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006396 347.0
PYH3_k127_8746330_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 342.0
PYH3_k127_8746330_15 reductase beta subunit K00395 - 1.8.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 309.0
PYH3_k127_8746330_16 ErfK ybiS ycfS ynhG family protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001162 276.0
PYH3_k127_8746330_17 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000266 245.0
PYH3_k127_8746330_18 Electron transfer DM13 - - - 0.000000000000000000000000000000000000000000000000000000000000000003723 229.0
PYH3_k127_8746330_19 Endonuclease/Exonuclease/phosphatase family - - - 0.0000000000000000000000000000000000000000000000000008564 193.0
PYH3_k127_8746330_2 Belongs to the RtcB family K14415,K18148 - 6.5.1.3 4.042e-216 679.0
PYH3_k127_8746330_20 Nitroreductase family - - - 0.000000000000000000000000000000000000000000003303 171.0
PYH3_k127_8746330_21 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000001043 167.0
PYH3_k127_8746330_22 glyoxalase bleomycin resistance protein dioxygenase - - - 0.000000000000000000000000000000000000002671 152.0
PYH3_k127_8746330_23 Archease protein family (MTH1598/TM1083) - - - 0.00000000000000000000000000000000000002339 150.0
PYH3_k127_8746330_24 Universal stress protein - - - 0.000000000000000000000000000000000001658 143.0
PYH3_k127_8746330_25 Nucleotidyltransferase domain K07075 - - 0.0000000000000000000000009877 108.0
PYH3_k127_8746330_26 Protein of unknown function DUF86 - - - 0.000000000000000000000001366 109.0
PYH3_k127_8746330_27 - - - - 0.000000000000000000001276 97.0
PYH3_k127_8746330_3 protein containing a von Willebrand factor type A (vWA) domain - - - 5.629e-214 675.0
PYH3_k127_8746330_4 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 - 6.3.4.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006332 572.0
PYH3_k127_8746330_5 AAA domain (dynein-related subfamily) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008811 571.0
PYH3_k127_8746330_6 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005155 473.0
PYH3_k127_8746330_7 Virulence factor BrkB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 446.0
PYH3_k127_8746330_8 Phosphoribosyl synthetase-associated domain K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 393.0
PYH3_k127_8746330_9 PFAM band 7 protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 377.0
PYH3_k127_8748889_0 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000226 290.0
PYH3_k127_8748889_1 glutamate--cysteine ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002674 289.0
PYH3_k127_8748889_2 GTP-binding protein K06207 - - 0.000000000000000000000000000000000000002463 147.0
PYH3_k127_8748889_3 Predicted integral membrane protein (DUF2189) - - - 0.00000000000022 79.0
PYH3_k127_8769750_0 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 566.0
PYH3_k127_8769750_1 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000438 320.0
PYH3_k127_8769750_2 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.00000000000000000000000000000000000000000000000000000004393 198.0
PYH3_k127_8769750_3 benzoyl-CoA reductase K04113 - 1.3.7.8 0.00000000000000000000000000006527 122.0
PYH3_k127_8777636_0 Cytochrome c7 and related cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007753 282.0
PYH3_k127_8777636_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000007572 241.0
PYH3_k127_8777636_2 Cytochrome c7 and related cytochrome c - - - 0.0000000000000000000000000000000000000000000000000000004331 200.0
PYH3_k127_8777636_3 Cytochrome c7 and related cytochrome c - - - 0.00000000000000000000000000002927 119.0
PYH3_k127_8777636_4 - - - - 0.0000000000000000000008952 109.0
PYH3_k127_8795748_0 FAD dependent oxidoreductase central domain - - - 3.78e-270 840.0
PYH3_k127_8795748_1 Amidohydrolase family K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 389.0
PYH3_k127_8804437_0 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 481.0
PYH3_k127_8804437_1 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006034 439.0
PYH3_k127_8804437_2 TIGRFAM phosphate ABC transporter, inner membrane subunit PstA K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008007 411.0
PYH3_k127_8804437_3 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002374 303.0
PYH3_k127_8804437_4 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001753 246.0
PYH3_k127_8804437_5 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000001048 127.0
PYH3_k127_8853603_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1377.0
PYH3_k127_8853603_1 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 3.883e-243 761.0
PYH3_k127_8853603_10 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000004424 184.0
PYH3_k127_8853603_11 Protein of unknown function (DUF498/DUF598) - - - 0.000000000000000000000000000000000000000002057 160.0
PYH3_k127_8853603_12 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.000000000000000000000000000000000000000003411 158.0
PYH3_k127_8853603_13 Acetyltransferase (GNAT) domain K00663 - 2.3.1.82 0.00000000000000000000001475 107.0
PYH3_k127_8853603_14 Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin K03636 - - 0.00000000000000000005439 93.0
PYH3_k127_8853603_2 Aminotransferase K14261 - - 4.698e-227 707.0
PYH3_k127_8853603_3 Threonine synthase K01733 - 4.2.3.1 1.551e-197 626.0
PYH3_k127_8853603_4 homoserine dehydrogenase K00003 - 1.1.1.3 8.799e-197 623.0
PYH3_k127_8853603_5 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002653 523.0
PYH3_k127_8853603_6 ABC-type branched-chain amino acid transport system, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 491.0
PYH3_k127_8853603_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002797 317.0
PYH3_k127_8853603_8 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000002433 241.0
PYH3_k127_8853603_9 PFAM molybdopterin biosynthesis MoaE K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000000000001526 223.0
PYH3_k127_8862133_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 1.916e-302 945.0
PYH3_k127_8862133_1 Histidine kinase - - - 0.00000000000000000000001366 102.0
PYH3_k127_8863897_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 3.556e-218 688.0
PYH3_k127_8863897_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 1.727e-200 629.0
PYH3_k127_8863897_10 Integral membrane protein TerC - - - 0.0000000000000000000000000000000000000000000000000000000000000000001018 239.0
PYH3_k127_8863897_11 Protein of unknown function (DUF2889) - - - 0.00000000000000000000000000000000000000000000000000000000001474 212.0
PYH3_k127_8863897_12 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.00000000000000000000000000000000000000000000000000000000003735 214.0
PYH3_k127_8863897_13 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.000000000000000000000000000000000000000002313 160.0
PYH3_k127_8863897_14 Modulates RecA activity K03565 - - 0.000000000000000000000000000000005864 133.0
PYH3_k127_8863897_15 - - - - 0.00000000000001405 77.0
PYH3_k127_8863897_2 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003525 581.0
PYH3_k127_8863897_3 Histidine kinase K07649 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002812 544.0
PYH3_k127_8863897_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006341 507.0
PYH3_k127_8863897_5 PFAM PhoH family protein K06217 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001585 444.0
PYH3_k127_8863897_6 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 437.0
PYH3_k127_8863897_7 Mg2 and Co2 transporter K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003488 392.0
PYH3_k127_8863897_8 response regulator K02483,K07666,K07774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001366 352.0
PYH3_k127_8863897_9 (FHA) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000241 260.0
PYH3_k127_8881956_0 - - - - 0.0000000000000004922 88.0
PYH3_k127_8881956_1 PFAM cytochrome c, class I K08738 - - 0.0000000000002929 73.0
PYH3_k127_8881956_2 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000004959 61.0
PYH3_k127_8895966_0 Beta-lactamase superfamily domain K00784 - 3.1.26.11 8.315e-230 726.0
PYH3_k127_8895966_1 ubiE/COQ5 methyltransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002139 471.0
PYH3_k127_8895966_10 Acetyltransferase (GNAT) domain K03829 - - 0.00000000000000000000000000000000000000000000000000000000005743 210.0
PYH3_k127_8895966_11 acetyltransferase - - - 0.000000000000000000000000000000000000000000000001961 178.0
PYH3_k127_8895966_12 SnoaL-like domain - - - 0.0000000000000000000000000000000000004988 144.0
PYH3_k127_8895966_13 Cro/C1-type HTH DNA-binding domain - - - 0.0000000000000000000000000000000002541 132.0
PYH3_k127_8895966_14 Addiction module toxin, RelE StbE family K07334 - - 0.000000000000000000000000000000002099 130.0
PYH3_k127_8895966_15 Cupin - - - 0.00000000000000000000000008034 111.0
PYH3_k127_8895966_17 thiolester hydrolase activity K17362 - - 0.0000000000001637 74.0
PYH3_k127_8895966_2 Protein of unknown function (DUF2950) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
PYH3_k127_8895966_20 Cupin domain - - - 0.0002532 48.0
PYH3_k127_8895966_3 lipolytic protein G-D-S-L family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002828 330.0
PYH3_k127_8895966_4 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 314.0
PYH3_k127_8895966_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001563 283.0
PYH3_k127_8895966_6 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000007785 253.0
PYH3_k127_8895966_7 molybdenum ion binding K07140 - - 0.000000000000000000000000000000000000000000000000000000000000000000009815 240.0
PYH3_k127_8895966_8 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000004102 216.0
PYH3_k127_8895966_9 Glutathione-dependent formaldehyde-activating enzyme family protein 4 - - - 0.0000000000000000000000000000000000000000000000000000000000004838 212.0
PYH3_k127_8913564_0 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 422.0
PYH3_k127_8913564_1 - - - - 0.0000000000000000000000000000000000000000000000000006024 202.0
PYH3_k127_8913564_2 LysR substrate binding domain - - - 0.0000008066 51.0
PYH3_k127_8913564_3 GtrA-like protein - - - 0.0002221 53.0
PYH3_k127_8920206_0 Ethylbenzene dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 436.0
PYH3_k127_8920206_1 permease K07089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007453 261.0
PYH3_k127_8920206_2 nucleoside-diphosphate sugar epimerase - - - 0.000000000000000000000000000000000000000000000000000000003569 202.0
PYH3_k127_8920206_3 Thioredoxin domain - - - 0.0000000000000000006304 89.0
PYH3_k127_8922925_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 1.359e-240 753.0
PYH3_k127_8922925_1 Penicillin amidase K01434 - 3.5.1.11 2.16e-235 754.0
PYH3_k127_8922925_10 Dehydrogenase K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 406.0
PYH3_k127_8922925_11 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008232 383.0
PYH3_k127_8922925_12 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002618 365.0
PYH3_k127_8922925_13 Protein of unknown function (DUF2891) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001052 367.0
PYH3_k127_8922925_14 Type ii and iii secretion system protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003405 268.0
PYH3_k127_8922925_15 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000006177 254.0
PYH3_k127_8922925_16 SelR domain K07305 - 1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000006002 217.0
PYH3_k127_8922925_17 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020,K08319 - 1.1.1.31,1.1.1.411 0.00000000000000000000000000000000000000000000000000000000007222 215.0
PYH3_k127_8922925_18 nucleoside-diphosphate sugar epimerase - - - 0.00000000000000000000000000000000000000000000005348 177.0
PYH3_k127_8922925_2 Extracellular solute-binding protein, family 5 middle family protein K02035 - - 1.626e-222 702.0
PYH3_k127_8922925_20 - - - - 0.00000000000001169 80.0
PYH3_k127_8922925_3 Polyphosphate kinase 2 (PPK2) K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004769 583.0
PYH3_k127_8922925_4 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 523.0
PYH3_k127_8922925_5 peptidase dimerisation domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003755 522.0
PYH3_k127_8922925_6 ABC-type dipeptide oligopeptide nickel transport K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 495.0
PYH3_k127_8922925_7 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 487.0
PYH3_k127_8922925_8 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 452.0
PYH3_k127_8922925_9 COG1233 Phytoene dehydrogenase and related proteins K09516,K09835 - 1.3.99.23,5.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 426.0
PYH3_k127_8923176_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1430.0
PYH3_k127_8923176_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 8.167e-244 773.0
PYH3_k127_8923176_10 TIGRFAM 2-aminoethylphosphonate ABC transport system, 1-aminoethylphosphonate-binding protein component K02012 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 503.0
PYH3_k127_8923176_11 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007143 470.0
PYH3_k127_8923176_12 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004879 420.0
PYH3_k127_8923176_13 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000169 418.0
PYH3_k127_8923176_14 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 383.0
PYH3_k127_8923176_15 a g-specific adenine glycosylase K03575 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003438 384.0
PYH3_k127_8923176_16 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005052 381.0
PYH3_k127_8923176_17 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 379.0
PYH3_k127_8923176_18 Displays ATPase and GTPase activities K06958 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006258 342.0
PYH3_k127_8923176_19 Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates K10563 - 3.2.2.23,4.2.99.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004896 334.0
PYH3_k127_8923176_2 type I phosphodiesterase nucleotide pyrophosphatase K19670 - 3.11.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 608.0
PYH3_k127_8923176_20 Esterase of the alpha-beta hydrolase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003656 313.0
PYH3_k127_8923176_21 COG0483 Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 294.0
PYH3_k127_8923176_22 Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system K02041 - 3.6.3.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002213 285.0
PYH3_k127_8923176_23 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000049 284.0
PYH3_k127_8923176_24 ABC transporter, phosphonate, periplasmic substrate-binding protein K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001251 275.0
PYH3_k127_8923176_25 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001628 269.0
PYH3_k127_8923176_26 ABC transporter permease K02042 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002875 270.0
PYH3_k127_8923176_27 Alcohol dehydrogenase GroES-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002068 256.0
PYH3_k127_8923176_28 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004166 246.0
PYH3_k127_8923176_29 PFAM binding-protein-dependent transport systems inner membrane component K02042 - - 0.00000000000000000000000000000000000000000000000000000000000000000348 235.0
PYH3_k127_8923176_3 permease K02011 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 612.0
PYH3_k127_8923176_30 COG1762 Phosphotransferase system mannitol fructose-specific IIA domain (Ntr-type) K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000009032 223.0
PYH3_k127_8923176_31 FCD - - - 0.0000000000000000000000000000000000000000000000000000000000003342 219.0
PYH3_k127_8923176_32 hydroperoxide reductase activity - - - 0.000000000000000000000000000000000000000000000000000000000007825 222.0
PYH3_k127_8923176_33 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000001831 206.0
PYH3_k127_8923176_34 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000006287 198.0
PYH3_k127_8923176_35 haloacid dehalogenase-like hydrolase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000007012 192.0
PYH3_k127_8923176_36 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.00000000000000000000000000000000000001466 151.0
PYH3_k127_8923176_37 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000001689 145.0
PYH3_k127_8923176_38 sigma 54 modulation protein K05808 - - 0.0000000000000000000000000000000006646 133.0
PYH3_k127_8923176_39 PFAM Acetyltransferase (GNAT) family K00657 - 2.3.1.57 0.000000000000000000000000000000003639 136.0
PYH3_k127_8923176_4 Dynamin family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 607.0
PYH3_k127_8923176_40 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000008091 131.0
PYH3_k127_8923176_41 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000001765 116.0
PYH3_k127_8923176_42 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.0000000000000000004615 96.0
PYH3_k127_8923176_43 PFAM PsiF repeat protein - - - 0.00000000006757 65.0
PYH3_k127_8923176_44 belongs to the aldehyde dehydrogenase family K00128 - 1.2.1.3 0.0000002264 57.0
PYH3_k127_8923176_45 Tetratricopeptide repeat - - - 0.000005176 59.0
PYH3_k127_8923176_5 Na Pi-cotransporter II-related protein K03324 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 593.0
PYH3_k127_8923176_6 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008665 580.0
PYH3_k127_8923176_7 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008385 546.0
PYH3_k127_8923176_8 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 523.0
PYH3_k127_8923176_9 belongs to the aldehyde dehydrogenase family K00130 - 1.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001496 520.0
PYH3_k127_894616_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 9.767e-310 968.0
PYH3_k127_894616_1 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 6.719e-292 915.0
PYH3_k127_894616_10 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001073 548.0
PYH3_k127_894616_11 HflC and HflK could encode or regulate a protease K04088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 464.0
PYH3_k127_894616_12 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001182 432.0
PYH3_k127_894616_13 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007812 411.0
PYH3_k127_894616_14 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001676 387.0
PYH3_k127_894616_15 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 362.0
PYH3_k127_894616_16 3'-5' exonuclease K07501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007057 360.0
PYH3_k127_894616_17 RNA polymerase sigma factor RpoS K03087 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 338.0
PYH3_k127_894616_18 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K17713 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 327.0
PYH3_k127_894616_19 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005932 280.0
PYH3_k127_894616_2 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 2.18e-268 831.0
PYH3_k127_894616_20 phosphoribosyltransferase K07101 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001275 261.0
PYH3_k127_894616_21 NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form K12410 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004811 264.0
PYH3_k127_894616_22 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000538 258.0
PYH3_k127_894616_23 PFAM fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000006125 250.0
PYH3_k127_894616_24 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000003772 235.0
PYH3_k127_894616_25 Tetratricopeptide repeat K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000004207 238.0
PYH3_k127_894616_26 Tetratricopeptide repeat-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
PYH3_k127_894616_27 peptidase K06194 - - 0.00000000000000000000000000000000000000000000000000000000000000004174 235.0
PYH3_k127_894616_28 Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins K00573 - 2.1.1.77 0.000000000000000000000000000000000000000000000000000000000000001834 225.0
PYH3_k127_894616_29 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000002519 214.0
PYH3_k127_894616_3 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 8.546e-219 687.0
PYH3_k127_894616_30 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000000000000000000000000000005638 203.0
PYH3_k127_894616_31 Protein of unknown function DUF47 K07220 - - 0.0000000000000000000000000000000000000000000000000003049 193.0
PYH3_k127_894616_32 Protein of unknown function (DUF456) K09793 - - 0.000000000000000000000000000000000000000000000000004759 185.0
PYH3_k127_894616_33 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.00000000000000000000000000000000000000000000000003401 180.0
PYH3_k127_894616_34 helix_turn_helix, mercury resistance - - - 0.000000000000000000000000000000000000000000000001835 177.0
PYH3_k127_894616_35 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000312 165.0
PYH3_k127_894616_36 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000000001806 147.0
PYH3_k127_894616_37 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.0000000000000000000000000000000000004239 142.0
PYH3_k127_894616_38 Helix-turn-helix domain K15539 - - 0.0000000000000000000000000005623 126.0
PYH3_k127_894616_39 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000003624 106.0
PYH3_k127_894616_4 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 1.9e-215 674.0
PYH3_k127_894616_40 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.00000000000000001276 87.0
PYH3_k127_894616_41 protein conserved in bacteria K09937 - - 0.00000000000009749 74.0
PYH3_k127_894616_42 dehydrogenase - - - 0.00006767 49.0
PYH3_k127_894616_5 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 3.557e-199 629.0
PYH3_k127_894616_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002043 612.0
PYH3_k127_894616_7 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 - 2.1.1.190 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 567.0
PYH3_k127_894616_8 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003537 559.0
PYH3_k127_894616_9 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003948 565.0
PYH3_k127_894857_0 PFAM Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005095 346.0
PYH3_k127_894857_1 metal-binding protein - - - 0.0000000000000000000000000000000000000000000000000000007959 196.0
PYH3_k127_8964421_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 432.0
PYH3_k127_8964421_1 OsmC-like protein - - - 0.00000000000000000000000000000003199 131.0
PYH3_k127_8980356_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 2361.0
PYH3_k127_8980356_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2296.0
PYH3_k127_8980356_10 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.0000000000000000000000000000000000000008021 151.0
PYH3_k127_8980356_11 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000002726 87.0
PYH3_k127_8980356_12 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.00000000000002828 72.0
PYH3_k127_8980356_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1234.0
PYH3_k127_8980356_3 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 338.0
PYH3_k127_8980356_4 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005633 305.0
PYH3_k127_8980356_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007039 274.0
PYH3_k127_8980356_6 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005945 267.0
PYH3_k127_8980356_7 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003233 250.0
PYH3_k127_8980356_8 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000002158 230.0
PYH3_k127_8980356_9 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.000000000000000000000000000000000000000000000000000033 189.0
PYH3_k127_8982868_0 acyl-CoA dehydrogenase K00249 - 1.3.8.7 1.613e-214 674.0
PYH3_k127_8982868_1 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 414.0
PYH3_k127_8982868_2 Belongs to the GST superfamily K00799,K11209 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007155 365.0
PYH3_k127_8982868_3 Staphylococcal nuclease homologues - - - 0.000000000000000000000000000000000000000000004854 169.0
PYH3_k127_8982868_4 Protein of unknown function (DUF1178) - - - 0.000000000000000000000000000000000000007459 153.0
PYH3_k127_8982868_5 Tautomerase enzyme - - - 0.0000000000000000000000000000000000003113 146.0
PYH3_k127_8982868_6 NAD-dependent DNA ligase - - - 0.00000000000000000000000000000000008993 141.0
PYH3_k127_8982868_7 Bacterial PH domain - - - 0.000000000000000000000000000002932 125.0
PYH3_k127_8993902_0 SurA N-terminal domain K03770 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001283 554.0
PYH3_k127_8993902_1 Dehydrogenase K00285 - 1.4.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001608 518.0
PYH3_k127_8993902_2 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001543 399.0
PYH3_k127_8993902_3 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003648 367.0
PYH3_k127_8993902_4 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758 - 4.2.1.136 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009682 349.0
PYH3_k127_8993902_5 ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 295.0
PYH3_k127_8993902_6 GDSL-like Lipase/Acylhydrolase K10804 - 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000003185 235.0
PYH3_k127_8993902_7 - - - - 0.00000000000001061 77.0
PYH3_k127_9001480_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0 1039.0
PYH3_k127_9001480_1 (twin-arginine translocation) pathway signal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002357 282.0
PYH3_k127_9001480_2 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001547 253.0
PYH3_k127_9001480_3 Cro/C1-type HTH DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000003043 217.0
PYH3_k127_9001480_4 - - - - 0.00000000000002216 81.0
PYH3_k127_9001480_6 Antibiotic biosynthesis monooxygenase - - - 0.00000374 53.0
PYH3_k127_9006464_0 SNARE associated Golgi protein - - - 5.077e-317 986.0
PYH3_k127_9006464_1 PFAM Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002981 449.0
PYH3_k127_9006464_2 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003192 321.0
PYH3_k127_9006464_3 COG0639 Diadenosine tetraphosphatase and related serine threonine protein phosphatases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005388 256.0
PYH3_k127_9006464_4 Sigma-70 region 2 K03088 - - 0.0000000000000000000000000000000000000000000000000000000000001202 218.0
PYH3_k127_9006464_5 6-phosphogluconate dehydrogenase, NAD-binding K00020,K00042 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0006082,GO:0006520,GO:0006573,GO:0006574,GO:0006807,GO:0008150,GO:0008152,GO:0008442,GO:0009056,GO:0009063,GO:0009081,GO:0009083,GO:0009987,GO:0016054,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0046395,GO:0055114,GO:0070013,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000003047 140.0
PYH3_k127_9006464_6 Glycosyl transferase family 2 - - - 0.0000009454 51.0
PYH3_k127_9006464_7 Transmembrane anti-sigma factor - - - 0.00002591 50.0
PYH3_k127_9015768_0 COG4631 Xanthine dehydrogenase, molybdopterin-binding subunit B K13482 - 1.17.1.4 0.0 1178.0
PYH3_k127_9015768_1 CO dehydrogenase flavoprotein C-terminal domain K13481 - 1.17.1.4 0.0000000000000000000000000000000000000000001443 161.0
PYH3_k127_9015768_2 COG1975 Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family K07402 - - 0.00000000000001197 79.0
PYH3_k127_9066973_0 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009969 499.0
PYH3_k127_9066973_1 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006707 341.0
PYH3_k127_9066973_10 Protein of unknown function (DUF433) - - - 0.00000000000000007587 88.0
PYH3_k127_9066973_11 - - - - 0.00000001312 58.0
PYH3_k127_9066973_2 cellulose binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 335.0
PYH3_k127_9066973_3 Predicted metal-binding integral membrane protein (DUF2182) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 327.0
PYH3_k127_9066973_4 Protein of unknown function (DUF1326) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006158 304.0
PYH3_k127_9066973_5 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000345 308.0
PYH3_k127_9066973_6 Cytochrome C biogenesis protein transmembrane region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006512 257.0
PYH3_k127_9066973_7 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000466 253.0
PYH3_k127_9066973_8 Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003578 247.0
PYH3_k127_9066973_9 - - - - 0.0000000000000000000002625 104.0
PYH3_k127_9119737_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 2.634e-221 699.0
PYH3_k127_9119737_1 Major Facilitator Superfamily - - - 0.00000000001655 67.0
PYH3_k127_9135527_0 Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN NodQ subfamily K00955,K00956 - 2.7.1.25,2.7.7.4 6.504e-292 907.0
PYH3_k127_9135527_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01531,K12955 - 3.6.3.2 1.434e-276 874.0
PYH3_k127_9135527_10 OPT oligopeptide transporter protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008667 507.0
PYH3_k127_9135527_11 periplasmic K11688 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001219 481.0
PYH3_k127_9135527_12 Transposase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005747 416.0
PYH3_k127_9135527_13 N-terminal half of MaoC dehydratase K09709,K18291 - 4.2.1.153,4.2.1.56 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005696 406.0
PYH3_k127_9135527_14 Methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 383.0
PYH3_k127_9135527_15 Enoyl-CoA hydratase/isomerase K11264 - 4.1.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004643 354.0
PYH3_k127_9135527_16 FtsX-like permease family K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 339.0
PYH3_k127_9135527_17 Belongs to the HpcH HpaI aldolase family K01644,K08691 - 4.1.3.24,4.1.3.25,4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001848 328.0
PYH3_k127_9135527_18 Creatinine amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008406 320.0
PYH3_k127_9135527_19 Haemolysin-III related K11068 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002077 278.0
PYH3_k127_9135527_2 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 6.451e-240 747.0
PYH3_k127_9135527_20 PFAM ABC transporter related K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005226 254.0
PYH3_k127_9135527_21 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001843 259.0
PYH3_k127_9135527_22 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000001136 214.0
PYH3_k127_9135527_23 Tellurite resistance protein TehB - - - 0.000000000000000000000000000000000000000000000000000219 194.0
PYH3_k127_9135527_24 Cysteine-rich secretory protein family - - - 0.0000000000000000000000000000000000000000000000006219 190.0
PYH3_k127_9135527_25 COG0175 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase) FAD synthetase and related enzymes K00957 - 2.7.7.4 0.0000000000000000000000000000000000000000001345 160.0
PYH3_k127_9135527_26 sulfate adenylyltransferase subunit 2 K00957 - 2.7.7.4 0.00000000000000000000000000000001221 127.0
PYH3_k127_9135527_27 enzyme binding - - - 0.000000000000000000000000000005322 124.0
PYH3_k127_9135527_28 Dodecin K09165 - - 0.00000000000000000000000000004411 118.0
PYH3_k127_9135527_29 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.000000000001135 75.0
PYH3_k127_9135527_3 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 6.576e-226 702.0
PYH3_k127_9135527_30 repeat-containing protein - - - 0.0000003138 62.0
PYH3_k127_9135527_31 TIGRFAM sulfate adenylyltransferase, small subunit K00957 - 2.7.7.4 0.00003364 46.0
PYH3_k127_9135527_32 - - - - 0.0003865 49.0
PYH3_k127_9135527_4 Peptidase family M48 - - - 1.898e-206 652.0
PYH3_k127_9135527_5 MmgE PrpD family protein - - - 2.307e-205 647.0
PYH3_k127_9135527_6 CoA-transferase family III K18289 - 2.8.3.22 8.656e-196 618.0
PYH3_k127_9135527_7 Zinc-binding dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005339 585.0
PYH3_k127_9135527_8 TIGRFAM 40-residue YVTN family beta-propeller repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003778 580.0
PYH3_k127_9135527_9 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009201 557.0
PYH3_k127_9162004_0 DNA polymerase X family K02347 - - 3.348e-234 737.0
PYH3_k127_9162004_1 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 447.0
PYH3_k127_9162004_10 DDE superfamily endonuclease - - - 0.0000000001217 63.0
PYH3_k127_9162004_11 - - - - 0.000000000155 67.0
PYH3_k127_9162004_2 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000626 346.0
PYH3_k127_9162004_3 VIT family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002032 286.0
PYH3_k127_9162004_4 PFAM Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001751 241.0
PYH3_k127_9162004_5 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000000000000000256 201.0
PYH3_k127_9162004_6 Domain in cystathionine beta-synthase and other proteins. - - - 0.0000000000000000000000000000000000003584 145.0
PYH3_k127_9162004_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000000000000000004004 138.0
PYH3_k127_9162004_8 response regulator - - - 0.000000000000000000000000008568 124.0
PYH3_k127_9162004_9 - - - - 0.00000000000000001153 88.0
PYH3_k127_9164405_0 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 6.942e-199 635.0
PYH3_k127_9164405_1 CoA-transferase family III K07749 - 2.8.3.16 2.66e-197 629.0
PYH3_k127_9164405_10 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000006489 267.0
PYH3_k127_9164405_11 Belongs to the CarB family K01955 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000005766 216.0
PYH3_k127_9164405_12 PFAM isochorismatase hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000001104 222.0
PYH3_k127_9164405_13 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000005136 206.0
PYH3_k127_9164405_14 PFAM Rhomboid family protein - - - 0.00000000000000000000000000000000000000000000000000117 202.0
PYH3_k127_9164405_15 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.000000000000000000000000000000000000000000000000003904 183.0
PYH3_k127_9164405_16 MAPEG family - - - 0.00000000000000000000000000000000002661 139.0
PYH3_k127_9164405_17 competence protein - - - 0.0000000000000000000000000000004998 138.0
PYH3_k127_9164405_18 PFAM porin Gram-negative type - - - 0.0000000001828 65.0
PYH3_k127_9164405_2 binding-protein-dependent transport systems inner membrane component K05845,K05846 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 602.0
PYH3_k127_9164405_3 Belongs to the CarA family K01956 - 6.3.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009825 577.0
PYH3_k127_9164405_4 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000783 579.0
PYH3_k127_9164405_5 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007833 504.0
PYH3_k127_9164405_6 Binding-protein-dependent transport system inner membrane component K02050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 480.0
PYH3_k127_9164405_7 PFAM ABC transporter related K02049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001893 460.0
PYH3_k127_9164405_8 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004753 372.0
PYH3_k127_9164405_9 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001147 287.0
PYH3_k127_9185120_0 mechanosensitive ion channel K03442,K16052 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000796 418.0
PYH3_k127_9185120_1 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003767 324.0
PYH3_k127_91917_0 Sulfatase - - - 5.419e-265 824.0
PYH3_k127_91917_1 Winged helix-turn helix - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007158 490.0
PYH3_k127_91917_2 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000009124 134.0
PYH3_k127_9199406_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 1.25e-321 991.0
PYH3_k127_9199406_1 Asp Glu hydantoin racemase K01799 - 5.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000398 284.0
PYH3_k127_9199406_2 FCD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009808 258.0
PYH3_k127_9199406_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.00000000000000000000000000000000000000000000000000007749 195.0
PYH3_k127_9199406_4 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000000001462 184.0
PYH3_k127_9199406_5 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.0000000000000000000000000000000000000000000004454 168.0
PYH3_k127_9199406_6 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.00000000000000000000000000000000000003307 145.0
PYH3_k127_9199406_7 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.00000000000000000000000000000000134 140.0
PYH3_k127_9220297_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 2.895e-226 719.0
PYH3_k127_9220297_1 fumarylacetoacetate (FAA) hydrolase K16171 - 3.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005598 524.0
PYH3_k127_9220297_10 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004742 322.0
PYH3_k127_9220297_11 Pfam Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 311.0
PYH3_k127_9220297_12 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000283 304.0
PYH3_k127_9220297_13 Polyphosphate kinase 2 (PPK2) K00937 - 2.7.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000569 304.0
PYH3_k127_9220297_14 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005966 301.0
PYH3_k127_9220297_15 FIST_C - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006065 306.0
PYH3_k127_9220297_16 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.0000000000000000000000000000000000000000000000000000000000000000002332 235.0
PYH3_k127_9220297_17 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000000000008087 220.0
PYH3_k127_9220297_18 Protein of unknown function (DUF3833) - - - 0.0000000000000000000000000000000000000000000000000000002339 198.0
PYH3_k127_9220297_19 SnoaL-like domain K01822 - 5.3.3.1 0.0000000000000000000000000000000000000000000000000002392 192.0
PYH3_k127_9220297_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 511.0
PYH3_k127_9220297_20 Glyoxalase-like domain - - - 0.000000000000000000000000000000000000000000000007785 178.0
PYH3_k127_9220297_21 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000006333 158.0
PYH3_k127_9220297_22 cell division protein - - - 0.000000000000000000000000000006914 127.0
PYH3_k127_9220297_23 - - - - 0.000000000000000000000000002239 120.0
PYH3_k127_9220297_24 Protein of unknown function (DUF3108) - - - 0.000000000000000000000000008808 123.0
PYH3_k127_9220297_25 Molybdopterin oxidoreductase Fe4S4 domain K00123 - 1.17.1.9 0.00000000000000000000000006648 109.0
PYH3_k127_9220297_26 Protein of unknown function (DUF3108) - - - 0.00000000000000000000005872 107.0
PYH3_k127_9220297_27 exo-alpha-(2->6)-sialidase activity K01179,K01186,K12373,K17624 - 3.2.1.18,3.2.1.4,3.2.1.52,3.2.1.97 0.000000000000001267 79.0
PYH3_k127_9220297_3 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001469 507.0
PYH3_k127_9220297_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008168,GO:0008610,GO:0008757,GO:0009058,GO:0009059,GO:0009273,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016741,GO:0019752,GO:0030312,GO:0032259,GO:0032787,GO:0034645,GO:0042546,GO:0043170,GO:0043436,GO:0044036,GO:0044038,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0070589,GO:0071554,GO:0071704,GO:0071766,GO:0071767,GO:0071768,GO:0071840,GO:0071944,GO:0072330,GO:1901576 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001097 490.0
PYH3_k127_9220297_5 MFS/sugar transport protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003931 388.0
PYH3_k127_9220297_6 Converts GTP to 7,8-dihydroneopterin triphosphate K01495,K09007 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 345.0
PYH3_k127_9220297_7 B12 binding domain K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003728 344.0
PYH3_k127_9220297_8 L-asparaginase II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003687 336.0
PYH3_k127_9220297_9 Protein of unknown function (DUF1365) K09701 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 323.0
PYH3_k127_9222154_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.465e-296 917.0
PYH3_k127_9222154_1 AMP-binding enzyme C-terminal domain - - - 2.351e-228 717.0
PYH3_k127_9222154_10 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 396.0
PYH3_k127_9222154_11 TonB dependent receptor K16092 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 413.0
PYH3_k127_9222154_12 abc transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001355 357.0
PYH3_k127_9222154_13 membrane transporter protein K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 331.0
PYH3_k127_9222154_14 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000001573 280.0
PYH3_k127_9222154_15 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001521 278.0
PYH3_k127_9222154_16 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001355 256.0
PYH3_k127_9222154_17 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000003709 231.0
PYH3_k127_9222154_18 helix_turn_helix, cAMP Regulatory protein K10914 - - 0.000000000000000000000000000000000000000000000000000001595 199.0
PYH3_k127_9222154_19 ABC transporter, ATP-binding protein K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000001148 194.0
PYH3_k127_9222154_2 Carbamoyl-phosphate synthase L chain, ATP-binding K01965 - 6.4.1.3 3.864e-223 701.0
PYH3_k127_9222154_20 Periplasmic binding protein K02016,K06858 - - 0.0000000000000000000000000000000001959 136.0
PYH3_k127_9222154_21 Cytochrome c K08738 - - 0.0000000000000000000000000000000003502 133.0
PYH3_k127_9222154_22 Protein of unknown function (DUF2721) - - - 0.0000000000000000000000000000001347 128.0
PYH3_k127_9222154_23 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.00000000000000000003478 97.0
PYH3_k127_9222154_24 - - - - 0.0000000000001476 73.0
PYH3_k127_9222154_25 - - - - 0.000611 46.0
PYH3_k127_9222154_3 AMP-binding enzyme C-terminal domain K18661 - - 4.052e-217 686.0
PYH3_k127_9222154_4 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002514 464.0
PYH3_k127_9222154_5 amino acid K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001153 460.0
PYH3_k127_9222154_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000694 445.0
PYH3_k127_9222154_7 Ketopantoate reductase PanE/ApbA C terminal K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 445.0
PYH3_k127_9222154_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008693 436.0
PYH3_k127_9222154_9 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 413.0
PYH3_k127_9237074_0 prepilin-type N-terminal cleavage methylation K02456 - - 0.000000000000000000000000000000000000000000000000000000005232 209.0
PYH3_k127_9237074_1 Type II secretion system protein G K02456 - - 0.000000000000000000000000000000000000000178 161.0
PYH3_k127_9237074_2 Type II secretory pathway pseudopilin - - - 0.000000000000003716 78.0
PYH3_k127_9237074_3 type II and III secretion system protein K02453 - - 0.0000000000009715 73.0
PYH3_k127_9256054_0 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 427.0
PYH3_k127_9256054_1 Carboxymuconolactone decarboxylase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004602 335.0
PYH3_k127_9256054_2 2Fe-2S iron-sulfur cluster binding domain K00523 - 1.17.1.1 0.0000000000000000000000000000004743 126.0
PYH3_k127_9271838_0 Domain of unknown function (DUF4188) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003937 259.0
PYH3_k127_9271838_1 PFAM extracellular solute-binding protein family 1 K02020,K22003 - 5.3.3.7 0.000000000000000000000000000000000000000000000000000000000000000000000004646 257.0
PYH3_k127_9271838_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000003362 188.0
PYH3_k127_9271838_3 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000005673 111.0
PYH3_k127_9271838_4 Helix-turn-helix XRE-family like proteins K07726 - - 0.00000000000000000000002723 102.0
PYH3_k127_9271838_5 Alpha beta hydrolase - - - 0.0000000000000000000002508 98.0
PYH3_k127_9271838_6 Cytotoxic translational repressor of toxin-antitoxin stability system - - - 0.0000000000000007925 78.0
PYH3_k127_9274668_0 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001492 383.0
PYH3_k127_9282766_0 2-aminobenzoate-CoA ligase K08295 - 6.2.1.32 2.848e-236 741.0
PYH3_k127_9282766_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 417.0
PYH3_k127_9282766_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000116 169.0
PYH3_k127_93162_0 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000527 436.0
PYH3_k127_93162_1 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003186 366.0
PYH3_k127_9333693_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1669.0
PYH3_k127_9333693_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 8.227e-222 708.0
PYH3_k127_9333693_10 4Fe-4S dicluster domain K16887 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000105 261.0
PYH3_k127_9333693_11 Histidine kinase K07673 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000001483 233.0
PYH3_k127_9333693_12 Calcineurin-like phosphoesterase superfamily domain K07095 - - 0.00000000000000000000000000000000000000000000000000000000000001186 219.0
PYH3_k127_9333693_13 AAA domain K02224 - 6.3.5.11,6.3.5.9 0.000000000000000000000000000000000000000000000000000000001659 204.0
PYH3_k127_9333693_14 - - - - 0.000000000000000000000000000000000000000000000000000006336 194.0
PYH3_k127_9333693_15 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000000000000002858 161.0
PYH3_k127_9333693_16 DsrC like protein K11179 - - 0.00000000000000000000000000000000000001027 151.0
PYH3_k127_9333693_17 Domain of unknown function (DUF202) K00389 - - 0.0000000000000000000000000000000000002702 144.0
PYH3_k127_9333693_18 - - - - 0.00000000000000000000001452 109.0
PYH3_k127_9333693_19 Iron-sulphur cluster biosynthesis K13628 - - 0.0000000000000002132 89.0
PYH3_k127_9333693_2 heterodisulfide reductase subunit A K16885 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002545 523.0
PYH3_k127_9333693_20 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 0.0001959 47.0
PYH3_k127_9333693_3 Sulphur transport K07112 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004001 486.0
PYH3_k127_9333693_4 PFAM 4Fe-4S K00184,K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002508 447.0
PYH3_k127_9333693_5 DMSO reductase anchor subunit (DmsC) K21309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 398.0
PYH3_k127_9333693_6 carboxymethylenebutenolidase activity K01061,K22249 - 3.1.1.45,3.1.1.76 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 338.0
PYH3_k127_9333693_7 Putative zinc- or iron-chelating domain K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 299.0
PYH3_k127_9333693_8 Bacterial regulatory proteins, luxR family K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001494 258.0
PYH3_k127_9333693_9 Succinate dehydrogenase fumarate reductase, flavoprotein subunit K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000002571 248.0
PYH3_k127_941494_0 B12 binding domain K00548 - 2.1.1.13 0.0 1827.0
PYH3_k127_941494_1 dna topoisomerase III K03169 - 5.99.1.2 0.0 1143.0
PYH3_k127_941494_10 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003358 472.0
PYH3_k127_941494_11 OsmC-like protein K06889,K07397 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 462.0
PYH3_k127_941494_12 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 403.0
PYH3_k127_941494_13 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 405.0
PYH3_k127_941494_14 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003439 376.0
PYH3_k127_941494_15 Tripartite ATP-independent periplasmic - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 368.0
PYH3_k127_941494_16 Peptidoglycan-binding LysM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 363.0
PYH3_k127_941494_17 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004089 356.0
PYH3_k127_941494_18 coenzyme F420-1:gamma-L-glutamate ligase activity K19285,K19286 - 1.5.1.38,1.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004645 344.0
PYH3_k127_941494_19 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003094 339.0
PYH3_k127_941494_2 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 5.814e-294 915.0
PYH3_k127_941494_20 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002821 327.0
PYH3_k127_941494_21 Glutamine amidotransferases class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007353 301.0
PYH3_k127_941494_22 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008294 294.0
PYH3_k127_941494_23 sequence-specific DNA binding K05804,K13631,K13632,K18325,K19056 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0006081,GO:0006082,GO:0006089,GO:0006355,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009438,GO:0009635,GO:0009636,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0019172,GO:0019219,GO:0019222,GO:0019243,GO:0019249,GO:0019752,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032787,GO:0032991,GO:0032993,GO:0035690,GO:0036245,GO:0042180,GO:0042182,GO:0042221,GO:0042493,GO:0042802,GO:0042803,GO:0043436,GO:0043565,GO:0044212,GO:0044237,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0046185,GO:0046394,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051596,GO:0051716,GO:0060255,GO:0061727,GO:0065007,GO:0070887,GO:0071310,GO:0071704,GO:0072330,GO:0072756,GO:0080090,GO:0097159,GO:0097237,GO:0140110,GO:1901363,GO:1901562,GO:1901575,GO:1901576,GO:1901615,GO:1901617,GO:1901654,GO:1901655,GO:1901700,GO:1901701,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006823 287.0
PYH3_k127_941494_24 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 279.0
PYH3_k127_941494_25 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000625 273.0
PYH3_k127_941494_26 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004828 256.0
PYH3_k127_941494_27 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000005626 250.0
PYH3_k127_941494_28 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000003056 244.0
PYH3_k127_941494_29 Fructosamine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000166 248.0
PYH3_k127_941494_3 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 7.968e-256 813.0
PYH3_k127_941494_30 PFAM nuclear protein SET K07117 - - 0.0000000000000000000000000000000000000000000000000000000000009443 215.0
PYH3_k127_941494_31 Domain of unknown function (DUF1993) K09983 - - 0.00000000000000000000000000000000000000000000000000000003567 205.0
PYH3_k127_941494_32 signal peptide protein - - - 0.000000000000000000000000000000000000000000000000001395 192.0
PYH3_k127_941494_33 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000003291 167.0
PYH3_k127_941494_34 TIGRFAM RNA polymerase sigma factor, sigma-70 family K03088 - - 0.0000000000000000000000000000000000000000001056 169.0
PYH3_k127_941494_35 Belongs to the Smg family K03747 - - 0.00000000000000000000000000000000000000001576 159.0
PYH3_k127_941494_36 Domain of unknown function (DUF1857) - - - 0.00000000000000000000000000000002532 131.0
PYH3_k127_941494_37 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.00000000000000000000000000000003992 147.0
PYH3_k127_941494_38 - - - - 0.0000000000000000000000000007444 119.0
PYH3_k127_941494_39 Protein of unknown function (DUF3567) - - - 0.0000000000000000000001598 108.0
PYH3_k127_941494_4 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 7.862e-213 685.0
PYH3_k127_941494_40 cobalamin synthesis protein - - - 0.00000001421 61.0
PYH3_k127_941494_41 response regulator - - - 0.00006446 47.0
PYH3_k127_941494_5 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 1.501e-205 647.0
PYH3_k127_941494_6 O-methyltransferase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003152 617.0
PYH3_k127_941494_7 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001318 592.0
PYH3_k127_941494_8 PFAM TrkA-N domain protein K03499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 567.0
PYH3_k127_941494_9 Beta-lactamase domain protein K06897 - 2.5.1.105 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003076 474.0
PYH3_k127_9502224_0 Haemolysin-type calcium-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001138 468.0
PYH3_k127_9502224_1 Bacterial transcriptional activator domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000544 468.0
PYH3_k127_9502224_2 PFAM Peptidoglycan-binding domain 1 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001962 325.0
PYH3_k127_9502224_3 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000002371 162.0
PYH3_k127_9530240_0 NHL repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002194 527.0
PYH3_k127_9530240_1 HupE / UreJ protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003546 534.0
PYH3_k127_9530240_2 4Fe-4S binding domain K18362 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 356.0
PYH3_k127_9530240_3 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007468 285.0
PYH3_k127_9530240_4 Domain of unknown function (DUF4439) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001575 275.0
PYH3_k127_9530240_5 Cytochrome c K08738 - - 0.000000000000000000000000000000000000000000000000001406 191.0
PYH3_k127_9530240_6 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000001961 166.0
PYH3_k127_9530240_7 transcriptional regulator - - - 0.0000000000000000000000000000000000005675 144.0
PYH3_k127_9530240_8 DMSO reductase anchor subunit (DmsC) K18363 - - 0.00000000000000000000000000001525 122.0
PYH3_k127_9593487_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006407 482.0
PYH3_k127_9593487_1 Prolyl oligopeptidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 407.0
PYH3_k127_9593487_2 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004545 319.0
PYH3_k127_9593487_3 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000001269 214.0
PYH3_k127_9593487_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000000000000000000000008867 182.0
PYH3_k127_9593487_5 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000002523 181.0
PYH3_k127_9593487_6 Putative cyclase - - - 0.00000000000000000000000000000000000000004677 155.0
PYH3_k127_9593487_7 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.00000000000000000000000000000009126 133.0
PYH3_k127_9593487_8 S1 RNA binding domain protein K08301 - - 0.0000000000000000001416 92.0