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Overview

ID MAG03226
Name PYH3_bin.30
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Chloroflexota
Class Dehalococcoidia
Order Dehalococcoidales
Family JAFGLR01
Genus JAFGLR01
Species
Assembly information
Completeness (%) 79.55
Contamination (%) 2.71
GC content (%) 50.0
N50 (bp) 4,127
Genome size (bp) 1,557,605

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1518

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1024426_0 Chemotaxis protein CheY K02479 - - 0.00000000000000000000000000001053 126.0
PYH3_k127_1024426_1 Belongs to the 'phage' integrase family K04763 - - 0.00001734 49.0
PYH3_k127_1024426_2 - - - - 0.00006446 47.0
PYH3_k127_1044321_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 301.0
PYH3_k127_1065744_0 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006975 539.0
PYH3_k127_1065744_1 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003798 387.0
PYH3_k127_1065744_2 indole-3-glycerol-phosphate synthase activity K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 291.0
PYH3_k127_1065744_3 Peptidase C26 K01658 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000137 294.0
PYH3_k127_110664_0 Endoribonuclease that initiates mRNA decay K18682 - - 2.261e-209 662.0
PYH3_k127_110664_1 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007689 602.0
PYH3_k127_110664_10 - - - - 0.000000001237 66.0
PYH3_k127_110664_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 539.0
PYH3_k127_110664_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 490.0
PYH3_k127_110664_4 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 319.0
PYH3_k127_110664_5 DNA polymerase alpha chain like domain K07053 - 3.1.3.97 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 303.0
PYH3_k127_110664_6 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000009803 214.0
PYH3_k127_110664_7 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000006549 208.0
PYH3_k127_110664_8 Modulates RecA activity K03565 - - 0.00000000000000000000000000000000000000000000001795 178.0
PYH3_k127_110664_9 Type IV pilus biogenesis stability protein PilW - - - 0.000000000000000000000008328 106.0
PYH3_k127_1107150_0 Transketolase, central region K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007391 361.0
PYH3_k127_1107150_1 Conserved hypothetical protein 95 - - - 0.000000000000000000000000000000000000000000000000000000000000000002683 231.0
PYH3_k127_1107150_2 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.000000000000000000000000000000000000000000000000000000006148 202.0
PYH3_k127_1107150_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000002119 136.0
PYH3_k127_1107150_4 Colicin V production protein K03558 - - 0.000000000000000000000000000000001936 137.0
PYH3_k127_1107150_5 XFP N-terminal domain K00615 - 2.2.1.1 0.0000000000000003651 78.0
PYH3_k127_1114531_0 XdhC Rossmann domain K07402 - - 0.000000000000000000000000000000000000000000000000000000000000007262 226.0
PYH3_k127_1114531_1 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.00000000000000000000000000000137 131.0
PYH3_k127_1114531_2 VWA domain containing CoxE-like protein K09989 - - 0.000000000000002312 76.0
PYH3_k127_116248_0 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000005205 153.0
PYH3_k127_116248_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion K18302 - - 0.000000106 64.0
PYH3_k127_1237349_0 Phosphotriesterase K07048 - - 0.000000000000000000000000000000000000000001696 163.0
PYH3_k127_1237349_1 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000000636 141.0
PYH3_k127_1244441_0 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.0000000000000000000000000000000000000001318 154.0
PYH3_k127_1244441_1 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000123 120.0
PYH3_k127_1244441_2 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000001916 113.0
PYH3_k127_1244441_3 Binds the 23S rRNA K02909 - - 0.00000000000000000000000007414 107.0
PYH3_k127_127263_0 PFAM acyl-CoA dehydrogenase domain protein K00249 - 1.3.8.7 0.0000000000000000000000000000000000000002173 165.0
PYH3_k127_127263_1 PFAM Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.00000000000000000004554 92.0
PYH3_k127_127263_2 Asp/Glu/Hydantoin racemase K16841 - 5.1.99.3 0.00000000002952 74.0
PYH3_k127_1286508_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1049.0
PYH3_k127_1286508_1 ROK family K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000004706 189.0
PYH3_k127_1286508_2 PFAM Major Facilitator Superfamily - - - 0.00000000000000000003577 103.0
PYH3_k127_1286508_3 AraC-like ligand binding domain - - - 0.00000000000003491 77.0
PYH3_k127_1286508_4 Steryl acetyl hydrolase K01066,K14731 - 3.1.1.83 0.00000004586 59.0
PYH3_k127_1296551_0 acid phosphatase activity - - - 0.000000000000000000000000009287 122.0
PYH3_k127_130138_0 PFAM Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000134 177.0
PYH3_k127_1322272_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 2.675e-210 664.0
PYH3_k127_1322272_1 Glycosyl transferase 4-like domain K15521 - 2.4.1.250 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 317.0
PYH3_k127_1322272_2 PFAM iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003225 296.0
PYH3_k127_1322272_3 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002361 258.0
PYH3_k127_135095_0 Amidohydrolase K07045 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007929 313.0
PYH3_k127_135095_1 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.0000000000000000000000000000000000000001672 157.0
PYH3_k127_135095_2 Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase K05808 - - 0.0000000000000000000000000000000000008033 145.0
PYH3_k127_135095_3 - - - - 0.000000000000000000000000009582 111.0
PYH3_k127_135095_4 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 GO:0003674,GO:0003824,GO:0003908,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006259,GO:0006281,GO:0006304,GO:0006307,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008168,GO:0008172,GO:0009987,GO:0016020,GO:0016740,GO:0016741,GO:0032259,GO:0033554,GO:0034641,GO:0035510,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0050896,GO:0051409,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:1901360 2.1.1.63 0.00000000001305 69.0
PYH3_k127_1359294_0 Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system K02010,K02045,K02049,K02068,K02071,K06857,K10112,K11072 - 3.6.3.25,3.6.3.30,3.6.3.31,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008536 305.0
PYH3_k127_1359294_1 PBP superfamily domain K05772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006329 294.0
PYH3_k127_1359294_2 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002928 279.0
PYH3_k127_1359294_3 Bacterial extracellular solute-binding protein K05772 - - 0.000000000000000000000000000000000000000000000000003066 190.0
PYH3_k127_1363426_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 584.0
PYH3_k127_1363426_1 4 iron, 4 sulfur cluster binding - - - 0.000000000000000000000000000000000138 133.0
PYH3_k127_1363426_3 COG0006 Xaa-Pro aminopeptidase - - - 0.000000000007767 74.0
PYH3_k127_1417013_0 cysteinyl-tRNA aminoacylation K01883 - 6.1.1.16 9.063e-194 614.0
PYH3_k127_1417013_1 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001951 271.0
PYH3_k127_1417013_2 TIGRFAM serine O-acetyltransferase K00640 - 2.3.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000005042 243.0
PYH3_k127_1417013_3 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335,K18331,K22339 - 1.12.1.3,1.17.1.11,1.6.5.3 0.00000000000000000000000000000000008864 134.0
PYH3_k127_1417013_4 Gamma-glutamyl cyclotransferase, AIG2-like - - - 0.0000000000000000000000000000000005513 134.0
PYH3_k127_1417013_5 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.00000000000000000000000000006993 118.0
PYH3_k127_143766_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 526.0
PYH3_k127_143766_1 N-terminal domain of toast_rack, DUF2154 - - - 0.0000005698 59.0
PYH3_k127_1476035_0 4Fe-4S dicluster domain K00184 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006377 291.0
PYH3_k127_1476035_1 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.0000000000000000000000004751 115.0
PYH3_k127_1492493_0 Aldehyde oxidase and xanthine dehydrogenase K00087,K03520 - 1.17.1.4,1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 468.0
PYH3_k127_1492493_1 acetyl-coa acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008625 423.0
PYH3_k127_1492493_2 xanthine dehydrogenase activity K11178 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0036094,GO:0042597,GO:0043167,GO:0043168,GO:0044464,GO:0048037,GO:0050660,GO:0050662,GO:0055114,GO:0097159,GO:1901265,GO:1901363 1.17.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000402 308.0
PYH3_k127_1537316_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000003032 164.0
PYH3_k127_1537316_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000003487 96.0
PYH3_k127_1551572_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 1.764e-297 929.0
PYH3_k127_1551572_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.947e-220 691.0
PYH3_k127_1551572_2 Belongs to the 5'-nucleotidase family K01081,K07004,K11751 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006163,GO:0006195,GO:0006213,GO:0006259,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0007155,GO:0007159,GO:0008150,GO:0008152,GO:0008252,GO:0008253,GO:0009056,GO:0009058,GO:0009116,GO:0009117,GO:0009164,GO:0009166,GO:0009987,GO:0016020,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0018130,GO:0019362,GO:0019438,GO:0019439,GO:0019637,GO:0019674,GO:0022610,GO:0031974,GO:0031981,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0034656,GO:0042578,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044270,GO:0044271,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044428,GO:0044444,GO:0044446,GO:0044464,GO:0046135,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0051186,GO:0055086,GO:0070013,GO:0071704,GO:0071944,GO:0072521,GO:0072523,GO:0072524,GO:0072527,GO:0072529,GO:0090304,GO:0098609,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1901657,GO:1901658 3.1.3.5,3.6.1.45 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008816 380.0
PYH3_k127_1551572_3 GPR1 FUN34 yaaH family protein K07034 - - 0.0000000000000000000000000000000000000004616 155.0
PYH3_k127_1553851_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 387.0
PYH3_k127_1553851_2 Thioredoxin-like - - - 0.000000000000001155 79.0
PYH3_k127_155400_0 PFAM Nitrate reductase gamma subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003003 362.0
PYH3_k127_1559442_0 PAC2 family K07159 - - 0.000000000000000000000000000000002038 140.0
PYH3_k127_1559442_1 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.000000000000000000000000000000304 139.0
PYH3_k127_1562463_0 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003376 367.0
PYH3_k127_1562463_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000001343 192.0
PYH3_k127_1562463_2 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000000000000000000000000000000000000000001026 190.0
PYH3_k127_1562463_3 Cyclic nucleotide-monophosphate binding domain - - - 0.00000000000000000000282 109.0
PYH3_k127_1562842_0 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005366 256.0
PYH3_k127_1562842_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768,K12132 GO:0000413,GO:0003674,GO:0003755,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016020,GO:0016021,GO:0016853,GO:0016859,GO:0018193,GO:0018208,GO:0019538,GO:0031224,GO:0031226,GO:0036211,GO:0040007,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044425,GO:0044459,GO:0044464,GO:0071704,GO:0071944,GO:0140096,GO:1901564 2.7.11.1,5.2.1.8 0.00000000000000000000000000000000000000000000000000000000002382 210.0
PYH3_k127_1562842_2 Peptidase family M48 K03799 - - 0.000000000000000000000000000000007966 130.0
PYH3_k127_1562842_3 Transcription factor zinc-finger K09981 - - 0.0000000000000000000000000000002053 128.0
PYH3_k127_1569796_0 Belongs to the aspartate-semialdehyde dehydrogenase family K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001102 460.0
PYH3_k127_1569796_1 form. Deacetylates the N-terminal lysine residue of Alba, the major archaeal chromatin protein and that, in turn, increases Alba's DNA binding affinity, thereby repressing transcription K12410 - - 0.00000000000000000000000000000000000000000000001594 178.0
PYH3_k127_1569796_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000001637 68.0
PYH3_k127_1572306_0 AAA domain K07028 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005634 402.0
PYH3_k127_1572306_1 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000004564 179.0
PYH3_k127_1572306_2 DNA polymerase alpha chain like domain K07053,K20859 - 3.1.3.97,3.1.4.57 0.00000000000000001152 89.0
PYH3_k127_1572306_3 AAA domain K07028 - - 0.0000000000009229 76.0
PYH3_k127_1591800_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009004 388.0
PYH3_k127_1594782_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 506.0
PYH3_k127_1594782_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 361.0
PYH3_k127_1594782_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005527 260.0
PYH3_k127_1594782_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001427 252.0
PYH3_k127_1594782_4 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000005904 187.0
PYH3_k127_1594782_5 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000001867 185.0
PYH3_k127_1594782_6 structural constituent of ribosome K02879 - - 0.0000000000000000000000000000000000000000002862 161.0
PYH3_k127_1594782_7 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000001209 156.0
PYH3_k127_1594782_8 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016020,GO:0019538,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0034641,GO:0034645,GO:0040007,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071944,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000004507 153.0
PYH3_k127_1633923_0 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation K03771 - 5.2.1.8 0.000000000000000000000000000009557 132.0
PYH3_k127_1634665_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 2.366e-224 707.0
PYH3_k127_1634665_1 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002645 457.0
PYH3_k127_1634665_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 458.0
PYH3_k127_1634665_3 Putative neutral zinc metallopeptidase K06973 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003447 276.0
PYH3_k127_1634665_4 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004357 277.0
PYH3_k127_1634665_5 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001733 268.0
PYH3_k127_1634665_6 Nitroreductase - - - 0.00000000000000000000000000000000000000000000000009948 184.0
PYH3_k127_1679366_0 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 GO:0003674,GO:0003824,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016854,GO:0052855,GO:0052856,GO:0052857 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006115 570.0
PYH3_k127_1679366_1 NeuB family K03856 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 383.0
PYH3_k127_1679366_2 PFAM Short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000002205 210.0
PYH3_k127_1679366_3 Alcohol dehydrogenase GroES-like domain K13953 - 1.1.1.1 0.00000000000000000000000000000000000000002825 156.0
PYH3_k127_168393_0 Phospholipid methyltransferase - - - 0.000000000000000000000000000000000000000005939 164.0
PYH3_k127_168393_1 Winged helix-turn-helix - - - 0.0000000000000000000000000000000001925 134.0
PYH3_k127_168393_2 - - - - 0.000000000000000000000004041 105.0
PYH3_k127_168393_3 GH3 auxin-responsive promoter - - - 0.00000001436 65.0
PYH3_k127_1729248_0 - - - - 0.00000000000000000168 95.0
PYH3_k127_1729248_1 Pfam:N_methyl_2 - - - 0.00000274 55.0
PYH3_k127_1754714_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.733e-261 815.0
PYH3_k127_1754714_1 Polyprenyl synthetase K00805,K02523 - 2.5.1.30,2.5.1.90 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 301.0
PYH3_k127_1754714_2 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.00000000000000000000000000000000000000000000002695 175.0
PYH3_k127_1810016_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.606e-202 634.0
PYH3_k127_1810016_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.000000000000000000000000001881 116.0
PYH3_k127_1810016_2 TIGRFAM preprotein translocase, YajC subunit K03210 - - 0.0000009366 51.0
PYH3_k127_182746_0 4Fe-4S dicluster domain - - - 1.21e-229 722.0
PYH3_k127_182746_1 PFAM Nitrate reductase gamma subunit - - - 0.00000000000000000000000000000000000000000000006709 181.0
PYH3_k127_182746_2 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0001959 47.0
PYH3_k127_1859018_0 Periplasmic Protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002376 263.0
PYH3_k127_1859018_1 Cadherin-like beta sandwich domain - - - 0.0000000000000004699 93.0
PYH3_k127_1862578_0 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 336.0
PYH3_k127_1862578_1 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.000000000000000000000000000000000000000000000000000000004085 214.0
PYH3_k127_1862578_2 - - - - 0.0000000000000000000000000000000000000000000000000000968 201.0
PYH3_k127_1870008_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007453 467.0
PYH3_k127_1870008_1 Preprotein translocase K03210 - - 0.0000000000000001359 84.0
PYH3_k127_1877901_0 Belongs to the glycosyl hydrolase 18 family K01183 - 3.2.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007137 389.0
PYH3_k127_192719_0 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0003674,GO:0003824,GO:0004017,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000001231 235.0
PYH3_k127_192719_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000007991 214.0
PYH3_k127_192719_2 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000004104 163.0
PYH3_k127_1938538_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 3.474e-232 735.0
PYH3_k127_1938538_1 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001787 318.0
PYH3_k127_1938538_2 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.0000000000000000000000000000000000000000000000004826 184.0
PYH3_k127_1938538_3 Amidohydrolase K10220,K14333 - 4.1.1.46,4.2.1.83 0.000000000000000000000000000000000000000000000003056 178.0
PYH3_k127_1938538_4 PFAM Nitroreductase - - - 0.00000000000000000000000000000000000002271 152.0
PYH3_k127_1938538_5 RNA methylase - - - 0.0000000000000000000000000000000000792 139.0
PYH3_k127_1938538_6 4Fe-4S ferredoxin, iron-sulfur binding family protein - - - 0.000000000000001741 78.0
PYH3_k127_1962104_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K07306,K08352 - 1.8.5.3,1.8.5.5 1.492e-194 629.0
PYH3_k127_1962104_1 4Fe-4S dicluster domain K00124,K07307 - - 0.00000000000000000000000000000000000000000000000000000000000000001002 229.0
PYH3_k127_1968387_0 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000704 587.0
PYH3_k127_1968387_1 fructose-1,6-bisphosphatase K02446 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030145,GO:0030388,GO:0042132,GO:0042578,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046364,GO:0046872,GO:0046914,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001841 375.0
PYH3_k127_1968387_2 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005176 333.0
PYH3_k127_1968387_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000005099 239.0
PYH3_k127_1968387_4 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.0000000000000000000000000000000000000000000000000000000000000000004928 236.0
PYH3_k127_1968387_5 ATP:corrinoid adenosyltransferase BtuR/CobO/CobP K19221 - 2.5.1.17 0.00000000000000000000000000000000000000000000000008845 183.0
PYH3_k127_1968387_6 RNase_H superfamily K07502 - - 0.00000001501 58.0
PYH3_k127_1992329_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007804 529.0
PYH3_k127_1992329_1 NADH ubiquinone oxidoreductase, F subunit, iron sulphur binding K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 301.0
PYH3_k127_1992329_2 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000007348 204.0
PYH3_k127_2003269_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005904 470.0
PYH3_k127_2003269_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000004255 158.0
PYH3_k127_2040979_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009594 528.0
PYH3_k127_2057828_0 leucyl-tRNA aminoacylation K01869 - 6.1.1.4 3.579e-241 754.0
PYH3_k127_2057828_1 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000005969 91.0
PYH3_k127_2071876_0 transport system involved in gliding motility, auxiliary component - - - 0.0000000000000000000000000000113 127.0
PYH3_k127_2071876_1 Domain of unknown function (DUF4340) - - - 0.000006483 55.0
PYH3_k127_2078391_0 HMGL-like K02594 - 2.3.3.14 9.913e-200 629.0
PYH3_k127_2078391_1 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 531.0
PYH3_k127_2078391_2 Isocitrate/isopropylmalate dehydrogenase K00030 - 1.1.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004036 508.0
PYH3_k127_2078391_3 2Fe-2S iron-sulfur cluster binding domain K00240 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 287.0
PYH3_k127_2078391_4 Succinate dehydrogenase/Fumarate reductase transmembrane subunit K00241 - - 0.000000000006823 71.0
PYH3_k127_2078391_5 succinate dehydrogenase activity K00242,K00246 - - 0.000001405 55.0
PYH3_k127_207882_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 1.8e-262 822.0
PYH3_k127_2084338_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002351 306.0
PYH3_k127_2084338_1 Amino acid permease K03294 - - 0.0000000000000000000000000000000000000000000000000000000000000004654 229.0
PYH3_k127_2084338_2 Helix-turn-helix domain - - - 0.000000000000000000007711 100.0
PYH3_k127_2084338_3 PFAM Radical SAM domain protein K22227 - - 0.000000000000008662 78.0
PYH3_k127_2129324_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 339.0
PYH3_k127_2129324_1 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000636 299.0
PYH3_k127_2129324_2 PFAM Translin K07477 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
PYH3_k127_2129324_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000002103 233.0
PYH3_k127_2129324_4 MFS transporter - - - 0.00000000000000000000000000000005123 141.0
PYH3_k127_2153929_0 COG0577 ABC-type antimicrobial peptide transport system permease component K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000105 296.0
PYH3_k127_2153929_1 Psort location CytoplasmicMembrane, score K02003 - - 0.0000000000000000000000000000000000000000000000003641 179.0
PYH3_k127_2160527_0 Belongs to the ClpA ClpB family K03696 - - 2.62e-235 738.0
PYH3_k127_2160527_1 - - - - 0.0000000000000000000000005138 115.0
PYH3_k127_2160527_2 Pfam SNARE associated Golgi protein - - - 0.000000000006262 66.0
PYH3_k127_2160527_3 methyltransferase K16648 - - 0.00026 50.0
PYH3_k127_2179560_0 Tfp pilus assembly protein FimV - - - 0.00002524 56.0
PYH3_k127_218252_0 Flavodoxin-like fold - - - 0.000000000000000000000000000000000000000000000000000000000005491 213.0
PYH3_k127_218252_1 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.00000000000000000000000000000000001974 140.0
PYH3_k127_2185362_0 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009739 427.0
PYH3_k127_2204217_0 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006623 462.0
PYH3_k127_2204217_1 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000002105 149.0
PYH3_k127_2204217_2 coenzyme F390 K01912 - 6.2.1.30 0.000000000000002771 89.0
PYH3_k127_2204217_3 Belongs to the peptidase S51 family K05995 - 3.4.13.21 0.000000000000003895 84.0
PYH3_k127_2246330_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004458 374.0
PYH3_k127_2246330_1 Cobinamide kinase / cobinamide phosphate guanyltransferase K02231 - 2.7.1.156,2.7.7.62 0.000000000000000000000000000000000000000000000000003344 187.0
PYH3_k127_2246330_2 diphthine-ammonia ligase activity K06927 - 6.3.1.14 0.00000000000000000000000000000000000000941 149.0
PYH3_k127_2270088_0 Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008328 281.0
PYH3_k127_2270777_0 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000001731 79.0
PYH3_k127_2270777_1 - - - - 0.0000002412 62.0
PYH3_k127_2294597_0 PFAM Cysteine-rich domain K11473 - - 0.00000000000000000000000000000000000000000000000000000006167 208.0
PYH3_k127_233015_0 PhoQ Sensor - - - 0.0000000000000000000000006482 121.0
PYH3_k127_2331555_0 ABC transporter - - - 0.0000000000000000000000000000000000000000000000000006402 192.0
PYH3_k127_2331555_1 Recombinase zinc beta ribbon domain - - - 0.0007647 44.0
PYH3_k127_2336085_0 PFAM Cytochrome b(N-terminal) b6 petB - - - 0.00000000000000000000000000000000000000371 153.0
PYH3_k127_2336085_1 Prokaryotic cytochrome b561 - - - 0.000000000000000000000000000004751 131.0
PYH3_k127_2374256_0 histidine kinase A domain protein K02484,K07642 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 306.0
PYH3_k127_2374256_1 Two component transcriptional regulator, winged helix family K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000001452 242.0
PYH3_k127_2374256_2 PFAM Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000005867 158.0
PYH3_k127_2381520_0 ABC-2 family transporter protein K01992 - - 0.0000000000000000000000000000000000000000000000009821 183.0
PYH3_k127_2381520_1 transport system involved in gliding motility, auxiliary K01992 - - 0.00000000000000000000000000000000000001837 157.0
PYH3_k127_2381520_2 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000006256 69.0
PYH3_k127_2381537_0 Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001642 279.0
PYH3_k127_2381537_1 type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis - - - 0.0000000000000000000000007096 114.0
PYH3_k127_2381537_2 von Willebrand factor (vWF) type A domain - - - 0.00000111 51.0
PYH3_k127_2407241_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.00000000000000000000000000000000000000000000000000000000000001209 244.0
PYH3_k127_2407241_1 cellulose binding - - - 0.00000000000000000000000000000000000000001817 158.0
PYH3_k127_2407241_2 PFAM Fibronectin type III domain - - - 0.00001985 58.0
PYH3_k127_2407241_3 TIGRFAM cytochrome C family protein - - - 0.0005431 53.0
PYH3_k127_2450916_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003054 268.0
PYH3_k127_2450916_1 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000169 218.0
PYH3_k127_2464633_0 AMP-dependent synthetase and ligase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 522.0
PYH3_k127_2464633_1 PFAM 4-hydroxyphenylacetate 3-hydroxylase N terminal K14534 - 4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000865 355.0
PYH3_k127_2464633_2 Rubredoxin-like zinc ribbon domain (DUF35_N) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000185 297.0
PYH3_k127_2464633_3 Dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000274 194.0
PYH3_k127_2464633_4 peptidase M24 - - - 0.0000000000000002027 86.0
PYH3_k127_2505498_0 Major facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000001099 236.0
PYH3_k127_2507483_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1139.0
PYH3_k127_2507483_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 1.264e-253 800.0
PYH3_k127_2507483_2 Belongs to the glycosyl hydrolase 57 family K16149 - 2.4.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003828 615.0
PYH3_k127_2507483_3 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003419 496.0
PYH3_k127_2507483_4 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002031 435.0
PYH3_k127_2507483_5 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 425.0
PYH3_k127_2507483_6 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003659 298.0
PYH3_k127_2507483_7 Fumarase C-terminus K01678 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000937 183.0
PYH3_k127_2507483_8 AMP binding - - - 0.000000000000000000000000000000000453 136.0
PYH3_k127_2507483_9 4-alpha-glucanotransferase K00705 - 2.4.1.25 0.000000000000000000000003774 103.0
PYH3_k127_2515401_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002299 415.0
PYH3_k127_2515401_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000513 384.0
PYH3_k127_2515401_10 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.00000000000000000000000000000000000000006297 153.0
PYH3_k127_2515401_11 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0008097,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.0000000000000000000000000000000000000003716 151.0
PYH3_k127_2515401_12 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000001247 149.0
PYH3_k127_2515401_13 Binds to the 23S rRNA K02876 - - 0.000000000000000000000000000000000000001318 152.0
PYH3_k127_2515401_14 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000003329 138.0
PYH3_k127_2515401_15 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000006394 106.0
PYH3_k127_2515401_16 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000007691 103.0
PYH3_k127_2515401_17 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001481 94.0
PYH3_k127_2515401_18 Ribosomal protein L30 K02907 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000004616 83.0
PYH3_k127_2515401_19 structural constituent of ribosome K02904 - - 0.000000000000002177 79.0
PYH3_k127_2515401_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 312.0
PYH3_k127_2515401_3 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000139 259.0
PYH3_k127_2515401_4 Ribosomal protein L6 K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000228 210.0
PYH3_k127_2515401_5 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000003431 205.0
PYH3_k127_2515401_6 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000005139 204.0
PYH3_k127_2515401_7 50S ribosomal protein L4 K02926 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000002157 198.0
PYH3_k127_2515401_8 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000004369 184.0
PYH3_k127_2515401_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.000000000000000000000000000000000000000000000001772 179.0
PYH3_k127_2585835_0 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 481.0
PYH3_k127_2585835_1 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009985 313.0
PYH3_k127_2585835_2 acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005353 283.0
PYH3_k127_2585835_3 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000001073 262.0
PYH3_k127_2585835_4 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000002452 244.0
PYH3_k127_259108_0 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 558.0
PYH3_k127_259108_1 AMP-binding enzyme C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008161 421.0
PYH3_k127_259108_2 4 iron, 4 sulfur cluster binding - - - 0.0000000000000000000000000000000001449 133.0
PYH3_k127_2603668_0 Probably functions as a manganese efflux pump - - - 0.00000000000000000000000000000000000000000000003274 176.0
PYH3_k127_2603668_1 inorganic phosphate transporter K03306 - - 0.000000000000000000000000000000000000000000001165 168.0
PYH3_k127_2609273_0 Acyl transferase domain K00645 - 2.3.1.39 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005935 340.0
PYH3_k127_2609273_1 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004316,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 291.0
PYH3_k127_2609273_2 PFAM Acyl-CoA dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001332 236.0
PYH3_k127_2609273_3 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000000002312 153.0
PYH3_k127_2609273_4 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.00000000000000000004491 96.0
PYH3_k127_2609273_5 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.0000000000000000515 82.0
PYH3_k127_2629644_0 Elongation factor G C-terminus K06207 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001007 611.0
PYH3_k127_2629644_1 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000002716 181.0
PYH3_k127_2638194_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006681 404.0
PYH3_k127_2638194_1 UbiA prenyltransferase family K02548 - 2.5.1.74 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 331.0
PYH3_k127_2638194_2 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000001795 109.0
PYH3_k127_2638194_3 Preprotein translocase SecG subunit K03075 - - 0.00000000000000000001152 93.0
PYH3_k127_2655004_0 Domain of unknown function (DUF362) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 305.0
PYH3_k127_2655004_1 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000000000000000000000000000004404 126.0
PYH3_k127_267671_0 Type II/IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004918 269.0
PYH3_k127_267671_1 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000002549 232.0
PYH3_k127_267671_2 4Fe-4S ferredoxin, iron-sulfur binding family protein - - - 0.0000000000000001319 82.0
PYH3_k127_267671_3 - - - - 0.00001096 50.0
PYH3_k127_2692572_0 TIGRFAM decaheme c-type cytochrome, OmcA MtrC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 401.0
PYH3_k127_2692572_1 DSBA-like thioredoxin domain - - - 0.0000000000000000000000000000000000000000000001654 173.0
PYH3_k127_2692572_2 sequence-specific DNA binding K18830 - - 0.000000000000000000000000000005751 123.0
PYH3_k127_2771747_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 4.245e-273 849.0
PYH3_k127_2771747_1 dihydroxy-acid dehydratase activity K01687 - 4.2.1.9 8.042e-247 773.0
PYH3_k127_2771747_2 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 5.326e-245 765.0
PYH3_k127_2771747_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009255 589.0
PYH3_k127_2771747_4 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001038 473.0
PYH3_k127_2771747_5 ACT domain K01653 - 2.2.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000002358 250.0
PYH3_k127_2771747_6 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.0000000000000000000000000000000000000000000001864 172.0
PYH3_k127_2771747_7 MgtC family K07507 - - 0.00000000000000000000000000000000000969 140.0
PYH3_k127_2771747_8 acylphosphatase activity K01512 - 3.6.1.7 0.00000000000000000006258 92.0
PYH3_k127_2778675_0 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004256 444.0
PYH3_k127_2778675_1 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000001653 231.0
PYH3_k127_2778675_2 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000002564 164.0
PYH3_k127_2783669_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000003 215.0
PYH3_k127_2793430_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 578.0
PYH3_k127_2793430_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003792 504.0
PYH3_k127_2793430_2 tRNA nucleotidyltransferase domain 2 putative K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 357.0
PYH3_k127_2793430_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 334.0
PYH3_k127_2793430_4 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.00000000000000000000000000000000000000008558 165.0
PYH3_k127_2823447_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 1.264e-219 703.0
PYH3_k127_2823447_1 Domain of unknown function (DUF1998) K06877 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003413 592.0
PYH3_k127_2823447_2 Protein of unknown function (DUF503) K09764 - - 0.000000000000000000004975 95.0
PYH3_k127_2823447_3 Binds directly to 16S ribosomal RNA K02968 - - 0.0000000000003315 72.0
PYH3_k127_2823447_4 HlyD family secretion protein K01993 - - 0.0000000005095 71.0
PYH3_k127_2835511_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000002045 180.0
PYH3_k127_2873124_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002092 558.0
PYH3_k127_2873124_1 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 359.0
PYH3_k127_2873124_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000672 268.0
PYH3_k127_2873124_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008594 250.0
PYH3_k127_2873124_4 Consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K07659 - - 0.00001934 53.0
PYH3_k127_2881503_0 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001824 374.0
PYH3_k127_2881503_1 Lamin Tail Domain - - - 0.0003359 49.0
PYH3_k127_2892397_0 Nickel-dependent hydrogenase K14126 - 1.8.98.5 6.267e-194 612.0
PYH3_k127_2892397_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001409 587.0
PYH3_k127_2892397_2 PFAM NADH ubiquinone oxidoreductase, 20 K14128 - 1.8.98.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 401.0
PYH3_k127_2892397_3 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 301.0
PYH3_k127_2892397_4 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 282.0
PYH3_k127_2892397_5 spore germination K03605 - - 0.0000000000000000000000000000000006293 136.0
PYH3_k127_2892397_6 Nickel-dependent hydrogenase K14126 - 1.8.98.5 0.00000000000000000000000000001532 119.0
PYH3_k127_2892397_7 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.000000000000000000000000001147 114.0
PYH3_k127_2892397_8 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000003444 97.0
PYH3_k127_2892397_9 Flavin containing amine oxidoreductase - - - 0.00000000001265 64.0
PYH3_k127_2916736_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 327.0
PYH3_k127_2948503_0 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001032 347.0
PYH3_k127_2948503_1 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000000000000001673 224.0
PYH3_k127_2948503_3 response regulator receiver K02479,K07692 - - 0.00000000002252 73.0
PYH3_k127_3040507_0 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 300.0
PYH3_k127_3040507_1 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000001379 160.0
PYH3_k127_3040507_2 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.0000000000000000000000000003588 126.0
PYH3_k127_3040507_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000000001567 81.0
PYH3_k127_3044025_0 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000813 477.0
PYH3_k127_3050686_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 3.036e-261 813.0
PYH3_k127_3050686_1 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 2.356e-214 671.0
PYH3_k127_3050686_2 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.644e-196 620.0
PYH3_k127_3050686_3 IMP dehydrogenase / GMP reductase domain K00088 - 1.1.1.205 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 513.0
PYH3_k127_3050686_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 495.0
PYH3_k127_3050686_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002236 303.0
PYH3_k127_3050686_6 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0002798 43.0
PYH3_k127_3055318_0 Elongation factor G C-terminus K06207 - - 0.000000000000000000000000000000000007754 138.0
PYH3_k127_3055318_1 Metal-dependent hydrolase K07043 - - 0.000001796 54.0
PYH3_k127_3090641_0 X-Pro dipeptidyl-peptidase domain protein K06978 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006276 297.0
PYH3_k127_3090641_1 - - - - 0.000000000000000000009382 94.0
PYH3_k127_3139561_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001049 610.0
PYH3_k127_3139561_1 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000295 421.0
PYH3_k127_3150193_0 Aldehyde ferredoxin oxidoreductase, N-terminal domain K03738 - 1.2.7.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007764 554.0
PYH3_k127_3150193_1 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 441.0
PYH3_k127_3150193_2 PFAM molybdopterin biosynthesis MoaE protein K03635,K21142 - 2.8.1.12 0.0000005819 55.0
PYH3_k127_3172484_0 Iron dependent K03709 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004286 265.0
PYH3_k127_3172484_1 Iron permease FTR1 K07243 - - 0.00000000000000000000000000000000000000000000000008102 184.0
PYH3_k127_3181803_0 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.00000000000000000000000000000000007198 141.0
PYH3_k127_3181803_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000301 108.0
PYH3_k127_3181803_2 Cytochrome c - - - 0.0000000000000000000000000691 112.0
PYH3_k127_3181803_3 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009060,GO:0009987,GO:0015672,GO:0015980,GO:0015988,GO:0015990,GO:0016020,GO:0022900,GO:0022904,GO:0034220,GO:0044237,GO:0044464,GO:0045333,GO:0051179,GO:0051234,GO:0055085,GO:0055114,GO:0071944,GO:0098655,GO:0098660,GO:0098662,GO:1902600 1.9.3.1 0.000000000000002482 79.0
PYH3_k127_3199882_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 4.34e-202 641.0
PYH3_k127_3199882_1 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 388.0
PYH3_k127_3199882_2 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003126 283.0
PYH3_k127_3199882_3 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000003331 185.0
PYH3_k127_3199882_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000005902 150.0
PYH3_k127_3239090_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000000000000000000000001167 215.0
PYH3_k127_3248287_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 384.0
PYH3_k127_3248287_1 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000009781 71.0
PYH3_k127_3322912_0 Calcineurin-like phosphoesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008783 276.0
PYH3_k127_3322912_1 ECF sigma factor K03088 - - 0.000000000000000000000000001134 119.0
PYH3_k127_3325601_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000001791 196.0
PYH3_k127_3364795_0 PFAM Polysulphide reductase, NrfD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002672 378.0
PYH3_k127_3364795_1 Beta-Casp domain K07576 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 298.0
PYH3_k127_3366591_0 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 436.0
PYH3_k127_3368791_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.463e-239 748.0
PYH3_k127_3368791_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001762 387.0
PYH3_k127_3368791_2 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.000000000000000000000000000000000000000003116 160.0
PYH3_k127_3368791_3 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109,K02113 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0030312,GO:0040007,GO:0044464,GO:0071944 - 0.0000000000000000000000001 114.0
PYH3_k127_3368791_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 0.0000000000000000000003958 96.0
PYH3_k127_3368791_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000001718 95.0
PYH3_k127_3368791_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000004946 73.0
PYH3_k127_3445951_0 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000005257 245.0
PYH3_k127_3445951_1 NfeD-like C-terminal, partner-binding K07403 - - 0.000000000000000000000000000000000000000000000000000000000007126 215.0
PYH3_k127_3477276_0 4Fe-4S dicluster domain - - - 4.326e-264 820.0
PYH3_k127_3477276_1 - - - - 0.00000000008852 65.0
PYH3_k127_3478764_0 Conserved region in glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 592.0
PYH3_k127_3478764_1 GXGXG motif - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 300.0
PYH3_k127_3492320_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 3.132e-316 979.0
PYH3_k127_3492320_1 Ftsk_gamma K03466 - - 5.241e-215 678.0
PYH3_k127_3492320_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000002544 208.0
PYH3_k127_349264_0 Kelch repeat - - - 0.0000000000000000000001515 113.0
PYH3_k127_349264_1 repeat protein - - - 0.0000000000000000469 95.0
PYH3_k127_3583065_0 Creatinase/Prolidase N-terminal domain K01262 - 3.4.11.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005832 357.0
PYH3_k127_3583065_1 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004062 334.0
PYH3_k127_3583065_2 PHP-associated - - - 0.0000000000000000000000000000000000000000000000000000007486 199.0
PYH3_k127_3589401_0 III protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009059 422.0
PYH3_k127_3589401_1 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000000000000004191 160.0
PYH3_k127_3589401_2 Enoyl-CoA hydratase/isomerase - - - 0.000000000000000000001467 97.0
PYH3_k127_3619196_0 PFAM Aminotransferase class I and II K11358 - 2.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 459.0
PYH3_k127_3619196_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000006694 242.0
PYH3_k127_3619196_2 Pyruvate ferredoxin/flavodoxin oxidoreductase K00180 - 1.2.7.8 0.000000000000000000000000000000000000000000000003385 179.0
PYH3_k127_3619726_0 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 457.0
PYH3_k127_3619726_1 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 348.0
PYH3_k127_3619726_2 calcium proton exchanger K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004088 259.0
PYH3_k127_3648940_0 4Fe-4S single cluster domain - - - 0.000000000000003651 87.0
PYH3_k127_3648940_1 metal-dependent hydrolase with the TIM-barrel fold - - - 0.00000000000007015 83.0
PYH3_k127_3648940_2 solute carrier family 16, member K08187,K08190 GO:0003674,GO:0005215,GO:0005342,GO:0005575,GO:0006810,GO:0006811,GO:0006820,GO:0008028,GO:0008150,GO:0008509,GO:0008514,GO:0015075,GO:0015318,GO:0015711,GO:0015718,GO:0015849,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0034220,GO:0044425,GO:0046942,GO:0046943,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0098656,GO:1903825,GO:1905039 - 0.0000002326 55.0
PYH3_k127_3679902_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000003713 225.0
PYH3_k127_3679902_1 SnoaL-like domain - - - 0.00000000000000000000000000000000000000000000000000000009908 201.0
PYH3_k127_3679902_2 - - - - 0.0000000000000000000000000000000000000000000147 169.0
PYH3_k127_3679902_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.00000001747 56.0
PYH3_k127_3679902_4 COG0006 Xaa-Pro aminopeptidase K01271 - 3.4.13.9 0.0002477 48.0
PYH3_k127_3698099_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003073 406.0
PYH3_k127_3698099_1 Histidine kinase - - - 0.000000000000000000000000000000000000000005623 162.0
PYH3_k127_3698099_2 PFAM regulatory protein LuxR - - - 0.00000000000000000000000000000002696 128.0
PYH3_k127_3698099_3 Member of the two-component regulatory system DegS DegU, which plays an important role in the transition growth phase K07777 - 2.7.13.3 0.00000000000000000001114 93.0
PYH3_k127_3700960_0 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005329 253.0
PYH3_k127_3700960_1 Transcriptional regulatory protein, C terminal K07658 - - 0.0000000000000000000000000000001145 124.0
PYH3_k127_3713922_0 DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity K03581 - 3.1.11.5 7.008e-214 676.0
PYH3_k127_3713922_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002216 578.0
PYH3_k127_3713922_2 Flavin containing amine oxidoreductase - - - 0.0000000000000000000000004825 106.0
PYH3_k127_3742238_0 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001159 277.0
PYH3_k127_3742238_1 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000004804 100.0
PYH3_k127_374693_0 Peptidase dimerisation domain K13049 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 312.0
PYH3_k127_3751304_0 Citrate transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 469.0
PYH3_k127_3751304_1 - - - - 0.0000002148 59.0
PYH3_k127_3771735_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005186 591.0
PYH3_k127_3771735_1 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 322.0
PYH3_k127_3771735_2 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000007802 236.0
PYH3_k127_381212_0 Thiolase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 536.0
PYH3_k127_381212_1 Probable zinc-ribbon domain - - - 0.00000000000000000000000000000000000002834 147.0
PYH3_k127_381212_2 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.0000000000000000000000000000000001775 134.0
PYH3_k127_3819469_0 DUF35 OB-fold domain, acyl-CoA-associated - - - 0.00000000000000000001958 94.0
PYH3_k127_3819469_1 COG0170 Dolichol kinase - - - 0.000229 51.0
PYH3_k127_3821716_0 ABC transporter substrate-binding protein K02035 - - 0.00000000000000000000000000000000000004126 156.0
PYH3_k127_3848738_0 Domain present in PSD-95, Dlg, and ZO-1/2. K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000629 264.0
PYH3_k127_3848738_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.0000000000000000000000000000000000000000000000000000000000000193 216.0
PYH3_k127_3856251_0 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000005577 244.0
PYH3_k127_3856251_1 Transcriptional regulator - - - 0.0000000004263 67.0
PYH3_k127_3913763_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 3.814e-217 692.0
PYH3_k127_3913763_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009098 569.0
PYH3_k127_3913763_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.000000000000000000000000000000003481 130.0
PYH3_k127_3913763_11 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K00332 - 1.6.5.3 0.00000000000000000000000000000000484 133.0
PYH3_k127_3913763_12 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000001194 80.0
PYH3_k127_3913763_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008754 539.0
PYH3_k127_3913763_3 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00123,K00266 - 1.17.1.9,1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000375 475.0
PYH3_k127_3913763_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008249 448.0
PYH3_k127_3913763_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009752 447.0
PYH3_k127_3913763_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000001104 248.0
PYH3_k127_3913763_7 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000000000002137 189.0
PYH3_k127_3913763_8 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000003412 157.0
PYH3_k127_3913763_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K05576 - 1.6.5.3 0.000000000000000000000000000000001096 139.0
PYH3_k127_3914550_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K00087 - 1.17.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005271 375.0
PYH3_k127_3914550_1 - - - - 0.0000000000000000000007077 103.0
PYH3_k127_3914550_2 Protein of unknown function (DUF1847) - - - 0.00000000000000000531 85.0
PYH3_k127_3918603_0 Phage integrase, N-terminal SAM-like domain K04763 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 406.0
PYH3_k127_3918603_1 Protein of unknown function (DUF541) K09807 - - 0.0002298 44.0
PYH3_k127_3957651_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001178 481.0
PYH3_k127_3957651_1 Phosphatidylethanolamine-binding protein - - - 0.00000000000000000000000001101 116.0
PYH3_k127_3957651_2 YHYH protein - - - 0.0000000000000000000000001059 115.0
PYH3_k127_3957651_3 Phosphatidylethanolamine-binding protein K06910 - - 0.0000000000009634 75.0
PYH3_k127_4035083_0 Glycosyltransferase group 2 family protein - - - 0.00000000000000000000000000000000003996 149.0
PYH3_k127_4041423_0 PFAM Polysulphide reductase, NrfD K00185 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001979 449.0
PYH3_k127_4041423_1 4Fe-4S dicluster domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 286.0
PYH3_k127_4041423_2 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.00000000000000000000000000006319 123.0
PYH3_k127_4041423_3 - - - - 0.000000000002716 66.0
PYH3_k127_4093770_0 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007178 399.0
PYH3_k127_4093770_1 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000001295 235.0
PYH3_k127_4093770_2 electron transfer activity K05337 - - 0.00000001502 58.0
PYH3_k127_4094666_0 PFAM Transketolase K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002446 318.0
PYH3_k127_4094666_1 PFAM ABC transporter K01990 - - 0.0000000000000000000000000000000002037 138.0
PYH3_k127_4094666_2 PFAM ABC-2 type transporter K01992 - - 0.000000000000000000000004837 112.0
PYH3_k127_4097793_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain - - - 0.000000000000000000000000000000000000000000000000000000000001805 219.0
PYH3_k127_4097793_1 Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000001257 208.0
PYH3_k127_4097793_2 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000009816 199.0
PYH3_k127_4097793_3 Methyltransferase, YaeB - - - 0.000000000000000000000001728 108.0
PYH3_k127_4099348_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003066 476.0
PYH3_k127_4099348_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 417.0
PYH3_k127_4099348_2 glycerolipid metabolic process K00057 GO:0003674,GO:0003824,GO:0004367,GO:0006072,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0019637,GO:0044237,GO:0046167,GO:0052646,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901137,GO:1901576 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007989 373.0
PYH3_k127_4099348_3 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000002527 262.0
PYH3_k127_4119048_0 ABC transporter, transmembrane region K06147,K18890 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001115 558.0
PYH3_k127_4119048_1 PFAM ABC transporter transmembrane region K06147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000434 541.0
PYH3_k127_4119048_10 Protein of unknown function (DUF664) - - - 0.0000000000000001477 87.0
PYH3_k127_4119048_11 Domain of unknown function (DUF4129) - - - 0.00000164 61.0
PYH3_k127_4119048_2 Aminotransferase class I and II K14155 - 4.4.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003424 496.0
PYH3_k127_4119048_3 ATPase associated with various cellular activities, AAA_3 K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003809 391.0
PYH3_k127_4119048_4 PFAM LmbE family protein K18455 - 3.5.1.115 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009262 301.0
PYH3_k127_4119048_5 Protein of unknown function DUF58 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007817 278.0
PYH3_k127_4119048_6 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000009401 220.0
PYH3_k127_4119048_7 Transmembrane secretion effector - - - 0.0000000000000000000000000000000000000000006945 172.0
PYH3_k127_4119048_8 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.000000000000000000000000000000000000000916 150.0
PYH3_k127_4119048_9 Transcriptional regulator PadR-like family - - - 0.0000000000000000000001696 103.0
PYH3_k127_4122284_0 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001534 554.0
PYH3_k127_4122284_1 FAD dependent oxidoreductase K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006756 529.0
PYH3_k127_4122284_2 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 358.0
PYH3_k127_4122284_3 tRNA synthetases class II (D, K and N) K04568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003561 356.0
PYH3_k127_4122284_4 Belongs to the LOG family K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 298.0
PYH3_k127_4122284_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000001036 177.0
PYH3_k127_4122284_6 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon - - - 0.000003469 58.0
PYH3_k127_4122284_7 Short C-terminal domain K08982 - - 0.00001003 50.0
PYH3_k127_4141255_0 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001716 248.0
PYH3_k127_4141255_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000003667 220.0
PYH3_k127_4156116_0 Belongs to the thiolase family K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008513 381.0
PYH3_k127_4156116_1 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000007071 234.0
PYH3_k127_4156116_2 PFAM CoA-binding domain protein K01905,K22224 - 6.2.1.13 0.00000000000000000000000000000000000000000000000000000005377 205.0
PYH3_k127_4185170_0 nodulation - - - 0.00000000000000000000000000000000000000000000000000001195 203.0
PYH3_k127_4241828_0 Heat shock 70 kDa protein K04043 - - 1.888e-303 942.0
PYH3_k127_4241828_1 NurA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 361.0
PYH3_k127_4241828_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004555 357.0
PYH3_k127_4241828_3 PFAM HAS barrel domain - - - 0.000000000000000000000000000000000000000000000000000000000000001642 224.0
PYH3_k127_4241828_4 AAA-like domain K06915 - - 0.000000000000000000000000000000000000000000000000000000000000004329 222.0
PYH3_k127_4241828_5 nuclease K00590,K01174,K02027 - 2.1.1.113,3.1.31.1 0.00000000000000000000000000000000000000000000000000000000000006025 223.0
PYH3_k127_4241828_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.0000000000000000000000000000000000000009689 154.0
PYH3_k127_4296602_0 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006032 455.0
PYH3_k127_4296602_1 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001786 447.0
PYH3_k127_4296602_2 Domain present in PSD-95, Dlg, and ZO-1/2. K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005719 351.0
PYH3_k127_4296602_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806,K12503 GO:0000287,GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016020,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0030145,GO:0033850,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046165,GO:0046872,GO:0046914,GO:0071704,GO:0071944,GO:1901576,GO:1901615,GO:1901617 2.5.1.31,2.5.1.68 0.00000000000000000000000000000000000000000000000000000000000000000000006779 248.0
PYH3_k127_4296602_4 Cytidylyltransferase family K00981 - 2.7.7.41 0.000000000000000000000000000000000000000000000000000000000000000000003494 243.0
PYH3_k127_4301345_0 AIR synthase related protein, C-terminal domain K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005777 426.0
PYH3_k127_4301345_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 417.0
PYH3_k127_4301345_2 Uncharacterized protein conserved in bacteria (DUF2344) - - - 0.000000000000000000000000000000000000000000000000000000002205 208.0
PYH3_k127_4301345_3 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000000003323 156.0
PYH3_k127_4301345_4 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000000000000000000003093 128.0
PYH3_k127_4301345_5 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.00000000000000000000001985 113.0
PYH3_k127_4301345_6 IMP cyclohydrolase activity K11175 - 2.1.2.2 0.0000002214 61.0
PYH3_k127_437651_0 Patatin-like phospholipase K07001 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000074 251.0
PYH3_k127_437651_1 FMN binding - - - 0.0000000000004617 76.0
PYH3_k127_4385606_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 1.761e-231 722.0
PYH3_k127_4385606_1 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001569 498.0
PYH3_k127_4385606_10 Regulatory protein, FmdB family - - - 0.0000000005948 63.0
PYH3_k127_4385606_11 PFAM NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.00005796 52.0
PYH3_k127_4385606_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003519 461.0
PYH3_k127_4385606_3 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001173 366.0
PYH3_k127_4385606_4 Amidohydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002751 310.0
PYH3_k127_4385606_5 aspartate carbamoyltransferase activity K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000006822 275.0
PYH3_k127_4385606_6 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 GO:0003674,GO:0003700,GO:0003824,GO:0004845,GO:0006139,GO:0006220,GO:0006221,GO:0006355,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008655,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009889,GO:0009987,GO:0010468,GO:0010556,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019693,GO:0031323,GO:0031326,GO:0034641,GO:0034654,GO:0043094,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0072527,GO:0072528,GO:0080090,GO:0090407,GO:0140110,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1903506,GO:2000112,GO:2001141 2.4.2.9 0.000000000000000000000000000000000000000000000000000000000002229 214.0
PYH3_k127_4385606_7 Biotin protein ligase C terminal domain K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000001865 211.0
PYH3_k127_4385606_8 - - - - 0.000000000000000000000000000000000000000000000001026 177.0
PYH3_k127_4385606_9 Membrane-bound serine protease (ClpP class) K07403 - - 0.000000000000000000000001125 108.0
PYH3_k127_4393090_0 Major facilitator superfamily K03449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 392.0
PYH3_k127_4393090_1 Rhomboid family - - - 0.00000000000000000000000000000000000000000001342 170.0
PYH3_k127_4393090_2 Acetyl xylan esterase (AXE1) K06889 - - 0.000000000001666 68.0
PYH3_k127_4393090_3 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K08234 - - 0.0003497 47.0
PYH3_k127_4399134_0 Cation transporter/ATPase, N-terminus K01531,K12955 - 3.6.3.2 8.191e-238 763.0
PYH3_k127_4399134_1 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001311 374.0
PYH3_k127_4399134_10 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000679 108.0
PYH3_k127_4399134_11 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000079 87.0
PYH3_k127_4399134_12 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000002727 76.0
PYH3_k127_4399134_2 60Kd inner membrane protein K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000009362 227.0
PYH3_k127_4399134_3 Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair K01356 - 3.4.21.88 0.0000000000000000000000000000000000000000000000000000000000000001214 227.0
PYH3_k127_4399134_4 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000001676 212.0
PYH3_k127_4399134_5 CorA-like Mg2+ transporter protein K03284 - - 0.00000000000000000000000000000000000000000000000000000000009927 216.0
PYH3_k127_4399134_6 KH domain K06346 - - 0.0000000000000000000000000000000000000000000000000005728 192.0
PYH3_k127_4399134_7 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000251 158.0
PYH3_k127_4399134_8 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.000000000000000000000000000009929 119.0
PYH3_k127_4399134_9 Single-strand binding protein family K03111 - - 0.0000000000000000000000003544 106.0
PYH3_k127_440859_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 2.995e-231 737.0
PYH3_k127_440859_1 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000006553 251.0
PYH3_k127_4449604_0 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 310.0
PYH3_k127_4449604_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000002318 144.0
PYH3_k127_4451825_0 COG0655 Multimeric flavodoxin WrbA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 546.0
PYH3_k127_4451825_1 4Fe-4S binding domain - - - 0.0000000000000000000000000000000000000000000000000000001155 203.0
PYH3_k127_4451825_2 Ferrous iron transport protein B K04759 - - 0.00000000000000000000000000000000000000000000003018 173.0
PYH3_k127_4451825_3 sequence-specific DNA binding - - - 0.0000000000000002121 80.0
PYH3_k127_450947_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 2.2e-304 953.0
PYH3_k127_450947_1 Dak1_2 K07030 - - 1.361e-204 650.0
PYH3_k127_450947_2 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 325.0
PYH3_k127_450947_3 cheY-homologous receiver domain - - - 0.0000000000000000000000000002296 118.0
PYH3_k127_450947_4 PFAM response regulator receiver - - - 0.0000000000000000000004586 100.0
PYH3_k127_450947_5 PFAM Cyclic nucleotide-binding domain - - - 0.00000003916 61.0
PYH3_k127_4541757_0 Alpha/beta hydrolase of unknown function (DUF1100) - - - 0.00000000000000000000000000000000000000000000000000000000000000002598 236.0
PYH3_k127_458266_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.000000000006586 66.0
PYH3_k127_4584445_0 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 9.737e-203 641.0
PYH3_k127_4584445_1 MarC family integral membrane protein K05595 - - 0.0000000000000000000000000000000000000000000001108 177.0
PYH3_k127_4584445_2 PFAM Archease protein family (DUF101 UPF0211) - - - 0.000000000000000000000000001407 118.0
PYH3_k127_4584445_3 YHS domain - - - 0.000000000000005079 76.0
PYH3_k127_4593614_0 Barrel-sandwich domain of CusB or HlyD membrane-fusion K02005 - - 0.000000000002564 78.0
PYH3_k127_4602247_0 ferredoxin oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 492.0
PYH3_k127_4602247_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 348.0
PYH3_k127_4602247_2 PFAM pyruvate ferredoxin flavodoxin oxidoreductase K00177 - 1.2.7.3 0.0000000000000000000000000000000000000000000005448 174.0
PYH3_k127_4602247_3 Mate efflux family protein K03327 - - 0.000000000000000000000000000000000000000000001857 175.0
PYH3_k127_4602247_4 4Fe-4S binding domain K00176 - 1.2.7.3 0.00000000000000002467 84.0
PYH3_k127_460765_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 0.0 1045.0
PYH3_k127_4626608_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000001364 228.0
PYH3_k127_4626608_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000001348 161.0
PYH3_k127_4626608_2 membrane - - - 0.0000002981 59.0
PYH3_k127_4664608_0 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000008545 210.0
PYH3_k127_4664608_1 COG1319 Aerobic-type carbon monoxide dehydrogenase middle subunit CoxM CutM homologs K03519,K11178 - 1.17.1.4,1.2.5.3 0.0000000000000000000000000000000000000000000000000000000009021 213.0
PYH3_k127_4664608_2 aldehyde oxidase and xanthine dehydrogenase a b hammerhead K00087 - 1.17.1.4 0.0000000000000000000007121 98.0
PYH3_k127_4695287_0 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000008117 169.0
PYH3_k127_4695287_1 - - - - 0.00000000000000002059 84.0
PYH3_k127_4696021_0 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00005384 51.0
PYH3_k127_4696021_1 translation initiation factor activity K06186,K12678 - - 0.0001933 51.0
PYH3_k127_4711504_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003051 563.0
PYH3_k127_4711504_1 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000000000000000000000001249 161.0
PYH3_k127_4712295_0 Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX K03405 - 6.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006316 584.0
PYH3_k127_4723198_0 Polymer-forming cytoskeletal - - - 0.0000000000000000000000000009378 127.0
PYH3_k127_472623_0 4Fe-4S ferredoxin iron-sulfur binding domain protein K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000155 196.0
PYH3_k127_472623_1 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.000000000000000000000005053 102.0
PYH3_k127_472623_2 PFAM methyl-viologen-reducing hydrogenase delta subunit - - - 0.00000000000000002782 83.0
PYH3_k127_4752049_0 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006791 563.0
PYH3_k127_4752049_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009551 548.0
PYH3_k127_4752049_2 Glycosyl transferases group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 448.0
PYH3_k127_4752049_3 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004111 404.0
PYH3_k127_4752049_4 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.000000000000000000000000000000000000000000007223 169.0
PYH3_k127_4762612_0 Major Facilitator Superfamily - - - 0.0000000000000000000000000003953 126.0
PYH3_k127_4765428_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001662 342.0
PYH3_k127_4796298_0 alpha-L-arabinofuranosidase - - - 0.0000000003842 66.0
PYH3_k127_4805603_0 Memo-like protein K06990 - - 0.000000003532 62.0
PYH3_k127_482085_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 432.0
PYH3_k127_4860564_0 E3 Ubiquitin ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007546 323.0
PYH3_k127_487916_0 cyclase family - - - 0.000000000000000000000000000000000000000000000005745 181.0
PYH3_k127_487916_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000008271 174.0
PYH3_k127_487916_2 Putative cyclase - - - 0.000000008726 57.0
PYH3_k127_4884532_0 diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003991 554.0
PYH3_k127_4894605_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000009424 191.0
PYH3_k127_4909837_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.771e-219 692.0
PYH3_k127_4909837_1 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000002002 257.0
PYH3_k127_4909837_2 Alpha/beta hydrolase family K06889,K07397 - - 0.000000000000000000000000000000000000000000000000000000003624 207.0
PYH3_k127_4925633_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003437 572.0
PYH3_k127_4925633_1 PFAM nitrogen-fixing NifU domain protein - - - 0.00000000000000000000000000263 112.0
PYH3_k127_4925633_2 Ribosomal protein S16 K02959 - - 0.0000000000000000000000001641 108.0
PYH3_k127_4925633_3 KH domain K06960 - - 0.00000000000000000000001706 101.0
PYH3_k127_4925633_4 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.0000001286 56.0
PYH3_k127_4935690_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 1.772e-245 768.0
PYH3_k127_4935690_1 4fe-4S ferredoxin, iron-sulfur binding domain protein K02572 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006950,GO:0006979,GO:0008150,GO:0044424,GO:0044464,GO:0050896 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001245 283.0
PYH3_k127_4935690_2 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000493 242.0
PYH3_k127_4935690_3 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain K17247 - - 0.000000000000000000000000000000000000000002073 159.0
PYH3_k127_4935690_4 Cupin domain - - - 0.00000000000000000000000000000000002702 137.0
PYH3_k127_4935690_5 - - - - 0.0000000000000000000000004519 106.0
PYH3_k127_4942346_0 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 389.0
PYH3_k127_4942346_1 Glutaredoxin - - - 0.0000000000000001194 80.0
PYH3_k127_4959731_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1172.0
PYH3_k127_4959731_1 Arylsulfotransferase (ASST) - - - 3.008e-219 689.0
PYH3_k127_4959731_2 Dolichyl-phosphate-mannose-protein mannosyltransferase K00728 - 2.4.1.109 0.000000000000000000000000000000000000000000000000000005698 209.0
PYH3_k127_4959731_3 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.0000000000000000000000000000001276 130.0
PYH3_k127_4987278_0 PFAM Integrase catalytic region K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 446.0
PYH3_k127_4987278_1 Transposase - - - 0.00000000000000000000000000000000000000000002296 162.0
PYH3_k127_4987278_2 - - - - 0.0004226 45.0
PYH3_k127_4987278_3 Subunit R is required for both nuclease and ATPase activities, but not for modification K01153 - 3.1.21.3 0.0007058 43.0
PYH3_k127_4997775_0 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009719 465.0
PYH3_k127_4997775_1 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000735 167.0
PYH3_k127_5030289_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006829 586.0
PYH3_k127_5030289_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000128 537.0
PYH3_k127_5030289_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000000000000000000001269 233.0
PYH3_k127_5030289_3 Amidohydrolase K07045,K14333,K20941 - 4.1.1.103,4.1.1.46 0.000000000000000000000000000000000000000000000000000000000000000004806 237.0
PYH3_k127_5030289_4 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000002119 212.0
PYH3_k127_5030289_5 peptidase U32 - - - 0.0000000000000000000000003515 106.0
PYH3_k127_5030289_6 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000048 103.0
PYH3_k127_5030289_7 - - - - 0.00000000000004158 74.0
PYH3_k127_5044706_0 Molybdopterin oxidoreductase Fe4S4 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 456.0
PYH3_k127_508018_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000001596 60.0
PYH3_k127_508018_1 phosphoesterase RecJ domain protein K06881 - 3.1.13.3,3.1.3.7 0.00003766 55.0
PYH3_k127_5082843_0 Major facilitator Superfamily K08168 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002808 401.0
PYH3_k127_5105580_0 PFAM Dak phosphatase K07030 - - 0.00000000000000000000000000000000000000000000000000000000000000000129 238.0
PYH3_k127_5105580_1 Uncharacterised protein, DegV family COG1307 - - - 0.000000000000000000000000000000000000000000000004637 183.0
PYH3_k127_5140797_0 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002453 393.0
PYH3_k127_5140797_1 KR domain K10780 GO:0000166,GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0005488,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0036094,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0048037,GO:0050661,GO:0050662,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:0097159,GO:1901265,GO:1901363,GO:1901576 1.3.1.104 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 290.0
PYH3_k127_5140797_2 PFAM short chain dehydrogenase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002382 280.0
PYH3_k127_5140797_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000001328 250.0
PYH3_k127_5140797_4 Dihydroxyacetone kinase family - - - 0.00000000000000000000000000000000000001494 155.0
PYH3_k127_5140797_5 PFAM MaoC like domain - - - 0.0000000000000000000000000002043 121.0
PYH3_k127_5140797_6 Domain of unknown function DUF83 - - - 0.00000000000000000000000001458 118.0
PYH3_k127_5140797_7 Belongs to the SOS response-associated peptidase family - - - 0.0000000000005268 71.0
PYH3_k127_5140797_8 Tetratricopeptide repeat - - - 0.0000001417 61.0
PYH3_k127_5140797_9 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 GO:0000035,GO:0000036,GO:0003674,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005975,GO:0006082,GO:0006139,GO:0006163,GO:0006629,GO:0006631,GO:0006633,GO:0006637,GO:0006643,GO:0006644,GO:0006664,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009245,GO:0009247,GO:0009259,GO:0009311,GO:0009312,GO:0009987,GO:0016020,GO:0016051,GO:0016053,GO:0019637,GO:0019693,GO:0019752,GO:0019842,GO:0030312,GO:0031177,GO:0032787,GO:0033218,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0044620,GO:0046394,GO:0046467,GO:0046483,GO:0046493,GO:0048037,GO:0051186,GO:0051192,GO:0055086,GO:0071704,GO:0071944,GO:0072330,GO:0072341,GO:0072521,GO:0090407,GO:0140104,GO:1901135,GO:1901137,GO:1901269,GO:1901271,GO:1901360,GO:1901564,GO:1901576,GO:1903509 - 0.0000007778 53.0
PYH3_k127_5199229_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 308.0
PYH3_k127_5199229_1 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001008 278.0
PYH3_k127_5207171_0 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 332.0
PYH3_k127_5223212_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005519 584.0
PYH3_k127_5223212_1 Sugar (and other) transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 462.0
PYH3_k127_5223212_2 Alpha amylase catalytic - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003127 406.0
PYH3_k127_5223212_3 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000006232 205.0
PYH3_k127_5223212_4 Fructose-bisphosphate aldolase class-II - - - 0.000000000000000000000000000000000000000000000000479 182.0
PYH3_k127_5239308_0 synthetase (ADP forming), alpha K01905,K09181,K22224 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006475,GO:0006807,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009266,GO:0009408,GO:0009628,GO:0009987,GO:0016043,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0018193,GO:0018205,GO:0018393,GO:0018394,GO:0019538,GO:0022607,GO:0032459,GO:0032462,GO:0034212,GO:0036211,GO:0043170,GO:0043254,GO:0043412,GO:0043543,GO:0043933,GO:0044085,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0052858,GO:0061733,GO:0065003,GO:0065007,GO:0071704,GO:0071840,GO:1901564 6.2.1.13 1.373e-290 917.0
PYH3_k127_5239308_1 Protein of unknown function DUF72 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004519 246.0
PYH3_k127_5239308_3 DNA integration - - - 0.00005571 47.0
PYH3_k127_5240324_0 - - - - 0.00000000000000000000000000000000000000000000009932 180.0
PYH3_k127_5240324_1 Metal-dependent hydrolase K07043 - - 0.000000000000000000000000000005575 122.0
PYH3_k127_524577_0 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004454 417.0
PYH3_k127_524577_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007065 359.0
PYH3_k127_524577_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000004163 211.0
PYH3_k127_5250737_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 4.584e-245 768.0
PYH3_k127_5250737_1 Domain of unknown function (DUF296) - - - 0.00000000000000000000000000000000000000000000000000000002604 200.0
PYH3_k127_5250737_2 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950,K17488 - 2.7.6.3,3.5.4.39 0.0000000000000000000000000000000000000000002302 163.0
PYH3_k127_5250737_3 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.000000000000000000000000000000001971 132.0
PYH3_k127_5250737_4 Belongs to the UPF0434 family - - - 0.0000000000000003401 80.0
PYH3_k127_5280802_0 ATPase AAA-2 domain protein K03696 - - 0.0 1050.0
PYH3_k127_5280802_1 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005565 492.0
PYH3_k127_5280802_10 2-methylcitrate dehydratase activity K01720 - 4.2.1.79 0.000000000000000000000000000000000000000000000002297 190.0
PYH3_k127_5280802_11 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.00000000000000000000000000000000000000000006024 166.0
PYH3_k127_5280802_12 transcriptional regulator PadR family K10947 - - 0.00000000000000000000000002206 113.0
PYH3_k127_5280802_13 - - - - 0.000000000000000000001007 95.0
PYH3_k127_5280802_14 Glutamine amidotransferase class-I - - - 0.00000000000000000005727 93.0
PYH3_k127_5280802_15 Bacterial protein of unknown function (DUF951) - - - 0.00000000000000003311 83.0
PYH3_k127_5280802_16 Putative regulatory protein - - - 0.0000000000000008517 81.0
PYH3_k127_5280802_17 CTP synthase K01937 - 6.3.4.2 0.0000000000001523 74.0
PYH3_k127_5280802_18 TIGRFAM Oxaloacetate decarboxylase, alpha subunit K01960 - 6.4.1.1 0.000000000007981 68.0
PYH3_k127_5280802_19 - - - - 0.00000000002238 65.0
PYH3_k127_5280802_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003719 430.0
PYH3_k127_5280802_3 Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily K17828 - 1.3.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002621 416.0
PYH3_k127_5280802_4 Domain of unknown function (DUF362) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003558 394.0
PYH3_k127_5280802_5 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003213 368.0
PYH3_k127_5280802_6 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002146 339.0
PYH3_k127_5280802_7 Belongs to the OMP decarboxylase family. Type 2 subfamily K01591 GO:0003674,GO:0003824,GO:0004590,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 314.0
PYH3_k127_5280802_8 regulation of RNA biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000007135 299.0
PYH3_k127_5280802_9 thiolester hydrolase activity K01179,K06889,K10773,K15853 - 3.2.1.4,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000003789 259.0
PYH3_k127_5300767_0 GXGXG motif - - - 6.471e-281 878.0
PYH3_k127_5300767_1 ABC transporter K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009475 253.0
PYH3_k127_5300767_2 Plays a major role in protein secretion by helping the post-translocational extracellular folding of several secreted proteins K03769,K07533 - 5.2.1.8 0.000000000007592 76.0
PYH3_k127_53107_0 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000001339 252.0
PYH3_k127_53107_1 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K01905,K11175,K22224 - 2.1.2.2,6.2.1.13 0.00000000000000000000000000000000000000000000000000000000000001994 225.0
PYH3_k127_53107_2 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000003245 94.0
PYH3_k127_53107_3 helix_turn_helix, Lux Regulon - - - 0.0000114 47.0
PYH3_k127_5323573_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K00123,K12527,K15022 - 1.17.1.10,1.17.1.9,1.97.1.9 2.37e-226 726.0
PYH3_k127_5323573_1 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 3.769e-208 660.0
PYH3_k127_5323573_2 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003527 377.0
PYH3_k127_5323573_3 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005419 369.0
PYH3_k127_5323573_4 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 - 2.3.1.29,2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003652 363.0
PYH3_k127_5323573_5 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 - 6.3.3.3 0.00000000000000000000000000000000000000000007054 170.0
PYH3_k127_5323573_6 Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met- O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.0000000000000005025 81.0
PYH3_k127_5350024_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004322 574.0
PYH3_k127_5350024_1 AMP-binding enzyme C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002111 453.0
PYH3_k127_5350024_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360 3.1.26.3 0.000000000000000000000000000000000000000000000000000000000000008832 223.0
PYH3_k127_5393832_0 COG1053 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.0000000000000000000000000000000000000000000000000000000002773 220.0
PYH3_k127_5393832_1 Similarity to COG0437 Fe-S-cluster-containing hydrogenase components 1(Evalue - - - 0.00000000000001116 76.0
PYH3_k127_5397730_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003047 406.0
PYH3_k127_5397730_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 393.0
PYH3_k127_5397730_2 HpcH/HpaI aldolase/citrate lyase family K01644 - 4.1.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001229 376.0
PYH3_k127_5397730_3 - - - - 0.000000000000000000000000000000008185 129.0
PYH3_k127_5406569_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 5.186e-206 650.0
PYH3_k127_5406569_1 Protein of unknown function (DUF1461) - - - 0.0000000000000000000000000000000000000001045 160.0
PYH3_k127_5406569_2 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.000000002705 58.0
PYH3_k127_5415885_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 404.0
PYH3_k127_5415885_1 Bifunctional nuclease K08999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000436 241.0
PYH3_k127_5451404_0 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006103 420.0
PYH3_k127_5451404_1 Involved in the synthesis of meso-diaminopimelate (m-DAP or DL-DAP), required for both lysine and peptidoglycan biosynthesis. Catalyzes the direct conversion of tetrahydrodipicolinate to LL-diaminopimelate K10206 - 2.6.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008165 285.0
PYH3_k127_5452334_0 Selenium-dependent molybdenum hydroxylase system protein, YqeB family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 299.0
PYH3_k127_5452334_1 Involved in chromosome partitioning - - - 0.0000000000000000000000000000000000000000000000002337 185.0
PYH3_k127_5452334_2 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K07141,K19190 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006725,GO:0006732,GO:0006753,GO:0006777,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019538,GO:0019637,GO:0019720,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0043170,GO:0043545,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0046872,GO:0051186,GO:0051188,GO:0051189,GO:0055086,GO:0061602,GO:0070567,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902759,GO:1902760 1.1.1.328,2.7.7.76 0.00000000000000000000000000000000000000001926 159.0
PYH3_k127_5452334_3 Sir2 family K12410 - - 0.00000000000006547 76.0
PYH3_k127_5461713_0 Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008127 323.0
PYH3_k127_5461713_1 Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.000000000000000000000000000000000002555 139.0
PYH3_k127_5461713_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000001145 68.0
PYH3_k127_5466668_0 Subtilase family K08651 - 3.4.21.66 0.000000000000652 75.0
PYH3_k127_5473415_0 - K03561,K12287 - - 0.000000001076 69.0
PYH3_k127_5536591_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 8.069e-222 696.0
PYH3_k127_5536591_1 histidyl-tRNA aminoacylation K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 576.0
PYH3_k127_5536591_2 MacB-like periplasmic core domain K02004,K05685 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 298.0
PYH3_k127_5536591_3 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006556 281.0
PYH3_k127_5536591_4 Secretion protein K02005 - - 0.000000000000003656 85.0
PYH3_k127_5575371_0 DHH family K07462 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 534.0
PYH3_k127_5575371_1 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000005843 163.0
PYH3_k127_5575371_2 Putative Fe-S cluster - - - 0.00000000000000000000211 100.0
PYH3_k127_5595690_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 484.0
PYH3_k127_5595690_1 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000001233 226.0
PYH3_k127_5595690_2 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000003093 52.0
PYH3_k127_5615615_0 PFAM aldo keto reductase K07079 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004296 454.0
PYH3_k127_5615615_1 geranylgeranyl reductase activity K06444,K17830 - 1.3.1.101,1.3.7.11,5.5.1.18 0.00000000000000000000000000000000000000000000000000001679 203.0
PYH3_k127_5615615_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000005 191.0
PYH3_k127_5615615_3 Dynamin family - - - 0.00000002458 59.0
PYH3_k127_5615615_4 Phosphoglycerate mutase family K22305 - 3.1.3.3 0.00001147 49.0
PYH3_k127_5617704_0 MatE - - - 0.0000000000000000000000000000000000000000000000000002629 198.0
PYH3_k127_5624768_0 Predicted membrane protein (DUF2339) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001337 257.0
PYH3_k127_5624768_1 transmembrane transporter activity K05820 - - 0.0000000000000000000000000000000000000000000000000000000000001894 225.0
PYH3_k127_5624768_2 integral membrane protein - - - 0.00000000006109 64.0
PYH3_k127_5634712_0 PFAM DNA methylase N-4 N-6 K00571,K07316 - 2.1.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004065 293.0
PYH3_k127_5634712_1 Trypsin K08070,K08372 - 1.3.1.74 0.00000000000000000000000000000000000000000000000000000000000000000009248 245.0
PYH3_k127_5634712_2 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000004694 152.0
PYH3_k127_5634712_3 - - - - 0.0000272 48.0
PYH3_k127_5688603_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 611.0
PYH3_k127_5688603_1 PHP domain K07053 - 3.1.3.97 0.00000000000000000000000000009631 123.0
PYH3_k127_5709114_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 1.815e-293 925.0
PYH3_k127_5709114_1 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007381 318.0
PYH3_k127_5709114_2 BadF/BadG/BcrA/BcrD ATPase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001116 258.0
PYH3_k127_5709114_3 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002779 252.0
PYH3_k127_5709114_4 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000002303 227.0
PYH3_k127_5709114_5 4Fe-4S dicluster domain K03390 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000018 171.0
PYH3_k127_5709114_6 PFAM 2-hydroxyglutaryl-CoA dehydratase, D-component - - - 0.000000000000000000264 101.0
PYH3_k127_5709114_8 dehydratase - - - 0.00003329 51.0
PYH3_k127_5738216_0 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003144 278.0
PYH3_k127_5738216_1 nucleic-acid-binding protein containing a Zn-ribbon - - - 0.000000000000000000001626 99.0
PYH3_k127_5738216_2 TIGRFAM Acetoacetyl-CoA synthase K01907 - 6.2.1.16 0.00000000001141 65.0
PYH3_k127_5744061_0 Putative cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001203 374.0
PYH3_k127_5744061_1 TIGRFAM hydro-lyase, Fe-S type, tartrate fumarate subfamily, alpha subunit K01677,K03779 - 4.2.1.2,4.2.1.32 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004189 336.0
PYH3_k127_5744061_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002129 335.0
PYH3_k127_5744061_3 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006233 321.0
PYH3_k127_5744061_4 fumarate reductase, flavoprotein subunit K00239,K00244 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 282.0
PYH3_k127_5744061_5 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000001463 221.0
PYH3_k127_5744061_6 Histidine kinase - - - 0.00000000000000000009681 92.0
PYH3_k127_5745577_0 Type II/IV secretion system protein K02669 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 399.0
PYH3_k127_5745577_1 Transglutaminase/protease-like homologues - - - 0.0000000000000000000000000000191 126.0
PYH3_k127_5757903_0 General secretory system II, protein E domain protein K02652 - - 0.0000000000000000000000000000000000000000000000000000007752 208.0
PYH3_k127_5769324_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 586.0
PYH3_k127_5769324_1 arginine biosynthetic process via ornithine K01755 - 4.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007516 567.0
PYH3_k127_5769324_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 530.0
PYH3_k127_5769324_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 431.0
PYH3_k127_5769324_4 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001235 263.0
PYH3_k127_5769324_5 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000006529 230.0
PYH3_k127_5769324_6 Ribosomal L28 family K02902 - - 0.000000000000000001115 91.0
PYH3_k127_5769324_7 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.00000000003515 69.0
PYH3_k127_5802265_0 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000002343 264.0
PYH3_k127_5823076_0 PFAM RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) - - - 0.000000000000000000000003274 105.0
PYH3_k127_5828853_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K06001 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008453 512.0
PYH3_k127_5836240_0 Amidohydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001271 405.0
PYH3_k127_5836240_1 Succinate dehydrogenase fumarate reductase flavoprotein subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002801 351.0
PYH3_k127_5836240_2 Oxidoreductase - - - 0.000000000000000000000000000000000000000000001651 177.0
PYH3_k127_5836240_3 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000001528 125.0
PYH3_k127_5836240_4 Glyoxalase-like domain K05606 - 5.1.99.1 0.00000000000000000000003391 103.0
PYH3_k127_5836240_5 Protein of unknown function (DUF2905) - - - 0.0000000000000000000174 93.0
PYH3_k127_5836240_6 4Fe-4S dicluster domain - - - 0.00000000000000000004951 91.0
PYH3_k127_5836240_7 Nickel ABC transporter substrate-binding protein K15584 - - 0.00001574 53.0
PYH3_k127_5836240_8 PFAM Cupin - - - 0.0002695 49.0
PYH3_k127_5860541_0 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007025 345.0
PYH3_k127_58767_0 domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 325.0
PYH3_k127_58767_1 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000006394 174.0
PYH3_k127_58767_2 Belongs to the 'phage' integrase family - - - 0.0000003093 52.0
PYH3_k127_5879896_0 DNA polymerase III, delta subunit K02341 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000001159 257.0
PYH3_k127_5879896_1 PSP1 C-terminal conserved region - - - 0.00000000000000000000000000000000000000000000000000000000000000000000004215 250.0
PYH3_k127_5879896_2 SMART HNH nuclease - - - 0.00000000000000000000000000000000000000000000000000001235 193.0
PYH3_k127_5939354_0 COG2133 Glucose sorbosone dehydrogenases - - - 0.0000000000000000000000000000000005807 141.0
PYH3_k127_5939354_2 DsrE/DsrF-like family - - - 0.00000000000006255 74.0
PYH3_k127_593966_0 PFAM Aminotransferase class-III K01845 - 5.4.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003513 299.0
PYH3_k127_593966_1 - - - - 0.00000006116 60.0
PYH3_k127_5947193_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000002695 140.0
PYH3_k127_594981_0 Belongs to the SOS response-associated peptidase family - - - 0.000000000000000000000000000000000000000000000000000000001041 209.0
PYH3_k127_594981_1 PFAM FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000000000000000000000000000000000006024 166.0
PYH3_k127_5951725_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005537 554.0
PYH3_k127_5985348_0 Peptidase dimerisation domain K01438,K01439 - 3.5.1.16,3.5.1.18 0.000000000000000000000000000000000000000003642 169.0
PYH3_k127_5985348_1 helix_turn_helix ASNC type K03718 - - 0.0000000000000002949 84.0
PYH3_k127_5999848_0 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006693 318.0
PYH3_k127_5999848_1 TIGRFAM molybdenum cofactor synthesis domain - - - 0.00000000000000000000000000000000000000000000000000000004391 201.0
PYH3_k127_5999848_2 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000228 173.0
PYH3_k127_5999848_3 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000007221 142.0
PYH3_k127_600704_0 B12 binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 610.0
PYH3_k127_600704_1 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008458 448.0
PYH3_k127_600704_2 fosmidomycin resistance protein K08223 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.0000000000000000001541 102.0
PYH3_k127_600704_3 Haloacid dehalogenase-like hydrolase K07025 - - 0.00000004378 56.0
PYH3_k127_6062030_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000005334 245.0
PYH3_k127_6062030_1 Phage derived protein Gp49-like (DUF891) - - - 0.000000000000000000000009985 104.0
PYH3_k127_6062030_2 Helix-turn-helix domain - - - 0.00000000000002145 76.0
PYH3_k127_6091106_0 transmembrane transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005685 256.0
PYH3_k127_6091106_1 peptidase, M24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000004683 243.0
PYH3_k127_6091106_2 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000001144 130.0
PYH3_k127_6091106_3 ABC-type transport system, involved in lipoprotein release, permease component K02004 - - 0.00000000000000002105 89.0
PYH3_k127_6091106_4 Uroporphyrinogen decarboxylase (URO-D) K01599 - 4.1.1.37 0.0000008636 54.0
PYH3_k127_6099846_0 Amidohydrolase K07045,K14333,K15063 - 4.1.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009972 407.0
PYH3_k127_6151820_0 Enoyl-(Acyl carrier protein) reductase K00059,K07535 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004597 291.0
PYH3_k127_6151820_1 PFAM Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000009051 187.0
PYH3_k127_6151820_2 3-hydroxyacyl-CoA dehydrogenase K15016 - 1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000001709 156.0
PYH3_k127_6170312_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 492.0
PYH3_k127_6170312_1 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 423.0
PYH3_k127_6170312_2 Bacterial transferase hexapeptide repeat K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000004791 188.0
PYH3_k127_6188585_0 Major facilitator superfamily MFS_1 - - - 0.0000000000000000000000001613 116.0
PYH3_k127_6188585_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000004595 102.0
PYH3_k127_6188585_2 - - - - 0.00002032 48.0
PYH3_k127_6191497_0 Recombinase zinc beta ribbon domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 444.0
PYH3_k127_621252_0 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 316.0
PYH3_k127_621252_1 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000001072 198.0
PYH3_k127_621252_2 NPCBM-associated, NEW3 domain of alpha-galactosidase - - - 0.000000000000000000000000000008478 130.0
PYH3_k127_621252_3 electron transfer flavoprotein, alpha subunit K03522 - - 0.000001086 50.0
PYH3_k127_6226927_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 4.902e-246 772.0
PYH3_k127_6226927_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000016 196.0
PYH3_k127_6239807_0 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000006653 108.0
PYH3_k127_6305334_0 Enoyl-CoA hydratase/isomerase K01692 GO:0003674,GO:0003824,GO:0004300,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016020,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0030312,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0044464,GO:0046395,GO:0055114,GO:0071704,GO:0071944,GO:0072329,GO:1901575 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000005827 218.0
PYH3_k127_6305334_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.0000000000000000000000000000000000000000000000000003192 196.0
PYH3_k127_6305334_2 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000003859 145.0
PYH3_k127_6307743_0 bacterial-type flagellum-dependent cell motility - - - 0.0000000000000000000000000000000000000000000006337 189.0
PYH3_k127_6349_0 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid K05555 - - 0.000000000000000000000000000000000000000000001923 175.0
PYH3_k127_6349_1 Putative redox-active protein (C_GCAxxG_C_C) - - - 0.000003354 55.0
PYH3_k127_6385647_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002318 282.0
PYH3_k127_6385647_1 COG0534 Na -driven multidrug efflux pump - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009832 254.0
PYH3_k127_6385647_10 4Fe-4S dicluster domain - - - 0.000000000573 63.0
PYH3_k127_6385647_11 Putative peptidoglycan binding domain - - - 0.00008039 50.0
PYH3_k127_6385647_2 PFAM NADH flavin oxidoreductase NADH oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000743 248.0
PYH3_k127_6385647_3 phosphatidylinositol kinase activity - - - 0.00000000000000000000000000000000000000000000000000000000000008087 220.0
PYH3_k127_6385647_4 Fumarate reductase flavoprotein C-term - - - 0.00000000000000000000000000000000000000000000009218 188.0
PYH3_k127_6385647_5 Protein of unknown function (DUF401) K09133 - - 0.00000000000000000000000000000000000000000002812 177.0
PYH3_k127_6385647_6 Inositol monophosphatase family - - - 0.0000000000000000000000000000000000000000007293 169.0
PYH3_k127_6385647_7 COG0006 Xaa-Pro aminopeptidase - - - 0.00000000000000000000000000000000002687 147.0
PYH3_k127_6385647_8 Alpha beta hydrolase K14731 - 3.1.1.83 0.000000000000000000000000000000001866 140.0
PYH3_k127_6385647_9 Protein of unknown function (DUF3090) - - - 0.0000000000000007524 83.0
PYH3_k127_6429367_0 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002127 265.0
PYH3_k127_6429367_1 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000001387 218.0
PYH3_k127_6429367_2 FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000000000008895 141.0
PYH3_k127_6429367_3 FAD linked oxidase domain protein - - - 0.000000000002695 69.0
PYH3_k127_6435431_0 DNA ligase K01971 - 6.5.1.1 4.82e-232 747.0
PYH3_k127_6435431_1 Arylsulfotransferase (ASST) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007906 398.0
PYH3_k127_6435431_2 acid phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002734 325.0
PYH3_k127_6435431_3 PFAM Haloacid dehalogenase domain protein hydrolase - - - 0.0000000000000000000000001356 115.0
PYH3_k127_6438545_0 Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis K01042 - 2.9.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000325 473.0
PYH3_k127_6438545_1 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.0000179 51.0
PYH3_k127_6438545_2 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0007745 42.0
PYH3_k127_6468440_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 2.122e-215 687.0
PYH3_k127_6468440_1 - - - - 0.0000000000000000002486 92.0
PYH3_k127_6468656_0 ABC transporter transmembrane region K06147 - - 4.011e-287 897.0
PYH3_k127_6468656_1 ABC transporter, transmembrane region K06147 - - 5.439e-260 821.0
PYH3_k127_6468656_2 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008741 293.0
PYH3_k127_6468656_3 Transmembrane secretion effector K08217 - - 0.00000000000000000000000000000000000005778 155.0
PYH3_k127_6468656_4 helix_turn_helix multiple antibiotic resistance protein - - - 0.0000000000000000000000000001502 120.0
PYH3_k127_6468656_5 PDZ domain (Also known as DHR or GLGF) K08372 - - 0.000000000000017 78.0
PYH3_k127_6472668_0 Belongs to the enoyl-CoA hydratase isomerase family - GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006635,GO:0008150,GO:0008152,GO:0009056,GO:0009062,GO:0009987,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000002358 211.0
PYH3_k127_6472668_1 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000002447 126.0
PYH3_k127_6474165_0 AMP-binding enzyme K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007141 362.0
PYH3_k127_6482240_0 Matrixin - - - 0.00000000000000000000001632 109.0
PYH3_k127_6482240_1 PemK-like, MazF-like toxin of type II toxin-antitoxin system K07171 - - 0.000000000000000006256 87.0
PYH3_k127_652166_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000043 248.0
PYH3_k127_6543113_0 R3H domain - - - 5.397e-203 643.0
PYH3_k127_6543113_1 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000458 469.0
PYH3_k127_6543113_2 transposition - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002451 304.0
PYH3_k127_6543113_3 Alpha/beta hydrolase of unknown function (DUF1057) - - - 0.00000000000000000000000000000000000000000000133 174.0
PYH3_k127_6543113_4 PFAM Integrase core domain - - - 0.0000001628 63.0
PYH3_k127_6551818_0 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000001109 250.0
PYH3_k127_6551818_1 ATPases associated with a variety of cellular activities K02003 - - 0.00000000000000000000000000000000000000000000000000000000000007044 220.0
PYH3_k127_6551818_2 BetI-type transcriptional repressor, C-terminal - - - 0.00000000000000000000000004041 115.0
PYH3_k127_6551818_3 membrane - - - 0.0000001036 60.0
PYH3_k127_6551818_4 PFAM NHL repeat - - - 0.000525 51.0
PYH3_k127_6562415_0 Mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000004311 211.0
PYH3_k127_6562415_1 dUTPase K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000007105 191.0
PYH3_k127_6570786_0 Carbamoyl-phosphate synthetase large chain, oligomerisation K01955 - 6.3.5.5 4.074e-210 658.0
PYH3_k127_6586512_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 2.015e-270 841.0
PYH3_k127_6586512_1 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 473.0
PYH3_k127_6586512_2 Poly A polymerase head domain K00974 - 2.7.7.72 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001739 303.0
PYH3_k127_6586512_3 MafB19-like deaminase K01493 - 3.5.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000007549 254.0
PYH3_k127_6586512_4 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000004317 212.0
PYH3_k127_6586512_5 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000004168 211.0
PYH3_k127_6586512_6 Telomere recombination K07566 - 2.7.7.87 0.00000000000000000000000000000000000000000000001214 179.0
PYH3_k127_6586512_7 Ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.0000000000000000000000000000000000000001043 154.0
PYH3_k127_6586512_8 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000394 66.0
PYH3_k127_6592901_0 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001131 349.0
PYH3_k127_6592901_1 cell redox homeostasis K00384,K03671 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000008299 231.0
PYH3_k127_6592901_2 YHYH protein - - - 0.000000000000000000008621 100.0
PYH3_k127_6592901_3 PFAM PEBP family protein K06910 - - 0.00000000008347 72.0
PYH3_k127_6594727_0 Elongator protein 3, MiaB family, Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000852 357.0
PYH3_k127_6594727_1 Phosphoribosyl transferase domain K07100 - - 0.000000000000000000000000000000000000000000000000000000000000000000003147 241.0
PYH3_k127_6594727_2 Competence-damaged protein K03743 - 3.5.1.42 0.0000000000000000000000000000000000000000001092 164.0
PYH3_k127_6594727_3 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000001238 145.0
PYH3_k127_6597208_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000285 270.0
PYH3_k127_6597208_1 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000004629 257.0
PYH3_k127_6597208_2 Dehydrogenase - - - 0.000000000000000001471 90.0
PYH3_k127_6597208_3 KR domain - - - 0.000000000000000003047 87.0
PYH3_k127_6608667_0 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000002029 63.0
PYH3_k127_661184_0 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 5.31e-272 848.0
PYH3_k127_661184_1 PFAM ABC transporter related K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001344 302.0
PYH3_k127_661184_2 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K02823 - - 0.00000000000000000000000000000000000000000000000000000000001154 215.0
PYH3_k127_661184_3 ABC-2 family transporter protein - - - 0.0000000001271 69.0
PYH3_k127_66162_0 Arsenical pump membrane protein K03893 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 452.0
PYH3_k127_6619838_0 Mate efflux family protein K03327 - - 0.000000000000000000000000000000006511 138.0
PYH3_k127_6619838_1 fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.000000000000000000001276 97.0
PYH3_k127_6638684_0 Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine K04487 - 2.8.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 413.0
PYH3_k127_6677566_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 7.25e-204 654.0
PYH3_k127_6677566_1 ATPase associated with various cellular activities, AAA_5 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005638 400.0
PYH3_k127_6677566_2 VWA containing CoxE family protein K09989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001332 351.0
PYH3_k127_6677566_3 Pyridine nucleotide-disulphide oxidoreductase K03387 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008953 311.0
PYH3_k127_6677566_4 Glutaredoxin K03676,K04771 - 3.4.21.107 0.000000000000000000000000000000003941 133.0
PYH3_k127_6677566_5 phosphatase 2C K17500 - 3.1.3.16 0.000003982 53.0
PYH3_k127_668821_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003992 426.0
PYH3_k127_668821_1 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.00000000000000000000000000000000000000000000000000000000000000000008395 233.0
PYH3_k127_668821_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.000000000000000000000000000000000000000000000000000000325 197.0
PYH3_k127_6707399_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003169 251.0
PYH3_k127_6707399_1 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0000000000000000003946 87.0
PYH3_k127_6720729_0 arginyl-tRNA aminoacylation K01887 - 6.1.1.19 8.673e-223 703.0
PYH3_k127_6721237_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009181 330.0
PYH3_k127_6728770_0 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 5.263e-201 634.0
PYH3_k127_6728770_1 Rubredoxin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002744 299.0
PYH3_k127_6728770_2 Ribonuclease R winged-helix domain K09720 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002995 303.0
PYH3_k127_6728770_3 Nitrogen regulatory protein P-II K04751 - - 0.00000000000000000000000000000000000000757 147.0
PYH3_k127_6728770_4 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.0000000000000000000000004165 109.0
PYH3_k127_6728770_5 - - - - 0.000000000000000001078 85.0
PYH3_k127_676148_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 415.0
PYH3_k127_676148_1 SAICAR synthetase K01923 - 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 399.0
PYH3_k127_676148_2 imidazoleglycerol-phosphate dehydratase activity K01693 - 4.2.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002398 283.0
PYH3_k127_676148_3 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013,K15509 - 1.1.1.23,1.1.1.308 0.0000000000000000000000000000000000000000000000000000000000000001546 228.0
PYH3_k127_676148_4 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.0000000000000000000000000000000000000000000000000000000000001481 216.0
PYH3_k127_6762229_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 9.587e-239 748.0
PYH3_k127_6762229_1 Thermophilic metalloprotease (M29) K19689 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009194 482.0
PYH3_k127_6762229_2 Insulinase (Peptidase family M16) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009764 407.0
PYH3_k127_6762229_3 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000001363 138.0
PYH3_k127_6800938_0 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 316.0
PYH3_k127_6800938_1 flavin adenine dinucleotide binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001138 263.0
PYH3_k127_6800938_11 COG NOG14600 non supervised orthologous group - - - 0.0003039 45.0
PYH3_k127_6800938_2 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009234 256.0
PYH3_k127_6800938_3 transmembrane transporter activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001428 234.0
PYH3_k127_6800938_4 Metallopeptidase family M24 - - - 0.0000000000000000000000000000000000000000000000000003031 200.0
PYH3_k127_6800938_5 Oxidoreductase family, C-terminal alpha/beta domain - - - 0.00000000000000000000000000000000000000000002287 174.0
PYH3_k127_6800938_6 Protein of unknown function (DUF1847) - - - 0.0000000000000000000000000000000007911 139.0
PYH3_k127_6800938_7 Creatinase/Prolidase N-terminal domain K01271 - 3.4.13.9 0.00000000000000000000000000000002325 140.0
PYH3_k127_6800938_8 - - - - 0.0000000000000000000000007918 104.0
PYH3_k127_6800938_9 Cupin domain - - - 0.00000000000001197 79.0
PYH3_k127_6804156_0 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001065 267.0
PYH3_k127_6804156_1 ATP-grasp domain K22224 - 6.2.1.13 0.000000000001666 68.0
PYH3_k127_6841178_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K08352,K21307 - 1.8.5.5,1.8.5.6 2.466e-201 657.0
PYH3_k127_6841178_1 PFAM 4Fe-4S binding domain K00184 - - 0.000000000000000000000000000000000000000000000000000000000000000000003958 241.0
PYH3_k127_6841178_2 Polysulphide reductase, NrfD - - - 0.000000000000000000000989 106.0
PYH3_k127_6841178_3 PFAM Nitrate reductase delta subunit - - - 0.0000000000847 71.0
PYH3_k127_6841178_4 SERine Proteinase INhibitors K13963 - - 0.00000005855 57.0
PYH3_k127_6848924_0 Conserved carboxylase domain K01960 - 6.4.1.1 2.337e-240 754.0
PYH3_k127_6848924_1 Biotin carboxylase C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008768 375.0
PYH3_k127_6848924_2 acyl-CoA dehydrogenase K18244 - - 0.000000000000000000000000000000000000004091 154.0
PYH3_k127_6852197_0 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
PYH3_k127_6852197_1 ATP-grasp domain K01903 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001272 377.0
PYH3_k127_6852197_2 CoA-ligase K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001179 349.0
PYH3_k127_6852197_3 DNA modification repair radical SAM protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003382 328.0
PYH3_k127_6852197_4 GYD domain - - - 0.0000000000000000000000005865 107.0
PYH3_k127_6852197_5 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000001612 86.0
PYH3_k127_6852197_6 - - - - 0.00000000001395 68.0
PYH3_k127_6876101_0 Iron-sulfur cluster binding domain of dihydroorotate dehydrogenase B K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005288 423.0
PYH3_k127_6876101_1 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002393 237.0
PYH3_k127_6876101_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000001876 209.0
PYH3_k127_6876101_3 Nitrous oxide-stimulated promoter - - - 0.0000000000000000000000000000000000001497 143.0
PYH3_k127_6876101_4 Domain of unknown function (DUF370) K09777 - - 0.0000000000000000000000000000000005072 133.0
PYH3_k127_6876101_5 Creatinase/Prolidase N-terminal domain - - - 0.000000000000000000000000000000001109 143.0
PYH3_k127_6876101_6 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000000000006371 128.0
PYH3_k127_6876101_7 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 0.00000000000001308 78.0
PYH3_k127_6876101_8 TIGRFAM glutamate synthase (NADPH), homotetrameric K00266 - 1.4.1.13,1.4.1.14 0.0000003592 53.0
PYH3_k127_6876101_9 Creatinase/Prolidase N-terminal domain K01262,K01271 - 3.4.11.9,3.4.13.9 0.000001204 60.0
PYH3_k127_6953910_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 3.919e-211 661.0
PYH3_k127_6953910_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 313.0
PYH3_k127_6953910_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005156 261.0
PYH3_k127_6953910_3 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000703 215.0
PYH3_k127_6953910_4 Hemerythrin HHE cation binding domain K09155 - - 0.000000000000000000000000000000000000000000000000000000000004965 213.0
PYH3_k127_6953910_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000000873 145.0
PYH3_k127_6953910_6 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000001748 129.0
PYH3_k127_6953910_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000105 77.0
PYH3_k127_6953910_8 Hemerythrin HHE cation binding domain protein K09155 - - 0.0000000000001542 73.0
PYH3_k127_6953910_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.000003068 51.0
PYH3_k127_6981355_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000001648 228.0
PYH3_k127_6981355_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000001023 222.0
PYH3_k127_6981355_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.0000000000000000000000000000001245 127.0
PYH3_k127_7050819_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1040.0
PYH3_k127_7050819_1 Single-strand binding protein family K03111 - - 0.00000000000000000000000000000000000000000000000000000000000115 211.0
PYH3_k127_7050819_2 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.000000000000000000000000000000000000000000002228 172.0
PYH3_k127_7050819_3 - - - - 0.0000000000000000000000000000000006291 132.0
PYH3_k127_7050819_4 COG0526, thiol-disulfide isomerase and thioredoxins - - - 0.0000000000000000000000000000002489 129.0
PYH3_k127_7050819_5 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000003634 97.0
PYH3_k127_705905_0 PFAM alpha beta hydrolase fold - - - 0.0000000000000000000000000000000000000000000000000009851 196.0
PYH3_k127_7080004_0 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000003519 220.0
PYH3_k127_7080004_1 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000002804 218.0
PYH3_k127_7080004_2 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770 - 4.6.1.12 0.000000000000000000000000000003839 120.0
PYH3_k127_709357_0 DAHP synthetase I family K03856 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002842 492.0
PYH3_k127_709357_1 Histone deacetylase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 336.0
PYH3_k127_709357_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001654 261.0
PYH3_k127_709357_3 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001126 261.0
PYH3_k127_7115356_0 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000009194 225.0
PYH3_k127_7115356_1 Cyclophilin-like K09143 - - 0.0000000000000000000000000000006359 125.0
PYH3_k127_7115356_2 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.00000000000000000000002516 104.0
PYH3_k127_7115356_3 FKBP-type peptidyl-prolyl cis-trans isomerase K01802 - 5.2.1.8 0.00000000000001318 75.0
PYH3_k127_7129912_0 COG0146 N-methylhydantoinase B acetone carboxylase, alpha subunit K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000341 557.0
PYH3_k127_7129912_1 N-methylhydantoinase A acetone carboxylase, beta subunit K01473 - 3.5.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008102 557.0
PYH3_k127_7129912_2 Class ii aldolase K01628 - 4.1.2.17 0.00000000000000000000000000000000000000000000000000000008891 202.0
PYH3_k127_7129912_3 ligase activity K01474 - 3.5.2.14 0.00000000000000000000000826 117.0
PYH3_k127_7129912_4 - - - - 0.0000000000000000000001949 107.0
PYH3_k127_7134264_0 PFAM NADH flavin oxidoreductase NADH oxidase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 304.0
PYH3_k127_7134264_1 With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD K10979 - - 0.0000000000000000000000000000000000000000000000000000000001947 213.0
PYH3_k127_7134264_2 LysE type translocator - - - 0.00000000000000000000000000000000000000000000000000001234 195.0
PYH3_k127_7134264_3 Bacterial regulatory proteins, luxR family - - - 0.0000000000000000000000000000000000000000000000001478 180.0
PYH3_k127_7134264_4 Arylsulfotransferase (ASST) - - - 0.0000000000004617 76.0
PYH3_k127_714006_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.192 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002287 330.0
PYH3_k127_714006_1 'Cold-shock' DNA-binding domain - - - 0.0000000000000000000000000000000000000000000001886 175.0
PYH3_k127_714006_2 Family of unknown function (DUF438) K09155 - - 0.0000000000000000000000000000000000000003387 156.0
PYH3_k127_714006_3 AMP binding - - - 0.0000000000000000000000000543 113.0
PYH3_k127_71697_0 GMC oxidoreductase K06151 - 1.1.99.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 437.0
PYH3_k127_71697_1 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.00000000000001701 77.0
PYH3_k127_71697_2 Secreted repeat of unknown function - - - 0.00000006243 61.0
PYH3_k127_7175874_0 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000008686 186.0
PYH3_k127_7175874_1 Bacterial fructose-1,6-bisphosphatase, glpX-encoded - - - 0.0000000000000000000000000000006041 124.0
PYH3_k127_7175874_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000005813 108.0
PYH3_k127_7175874_3 - - - - 0.0000000000000001641 79.0
PYH3_k127_7186286_0 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 3.559e-196 625.0
PYH3_k127_7186286_1 Radical_SAM C-terminal domain K07739 - 2.3.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 607.0
PYH3_k127_7186286_10 Thioredoxin - - - 0.00000000000000000000000003176 115.0
PYH3_k127_7186286_11 - - - - 0.0000000000000000611 81.0
PYH3_k127_7186286_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000703 335.0
PYH3_k127_7186286_3 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008383 285.0
PYH3_k127_7186286_4 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002126 279.0
PYH3_k127_7186286_5 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001711 262.0
PYH3_k127_7186286_6 Beta-lactamase superfamily domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000001045 242.0
PYH3_k127_7186286_7 Hit family K19710 - 2.7.7.53 0.00000000000000000000000000000000000000000000000000000000000000007299 225.0
PYH3_k127_7186286_8 Shikimate kinase K00891 - 2.7.1.71 0.0000000000000000000000000000000000000002834 155.0
PYH3_k127_7186286_9 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000002232 128.0
PYH3_k127_7233686_0 belongs to the thioredoxin family K20444,K20543 - - 0.00000000000000000000000000000000000000000000001008 183.0
PYH3_k127_7233686_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 GO:0005575,GO:0005623,GO:0005886,GO:0008150,GO:0016020,GO:0040007,GO:0044464,GO:0071944 4.2.1.20 0.0000001856 60.0
PYH3_k127_7233686_2 Rhodanese-like domain - - - 0.000001394 57.0
PYH3_k127_7234576_0 PFAM Nucleotidyl transferase K00973 - 2.7.7.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001479 365.0
PYH3_k127_7234576_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000004404 188.0
PYH3_k127_7318513_0 Trehalase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002052 270.0
PYH3_k127_7318513_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.0000000000000000000000000000000000000000000000000000000000000002613 227.0
PYH3_k127_7318513_2 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000004198 229.0
PYH3_k127_7318513_3 helix_turn_helix isocitrate lyase regulation K13641 - - 0.000000000000000000000000000000000000000000000000000002261 200.0
PYH3_k127_7318513_4 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000002489 162.0
PYH3_k127_7318513_5 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000001466 153.0
PYH3_k127_7318513_6 Belongs to the glycosyl hydrolase 8 (cellulase D) family - - - 0.00000000000000003055 96.0
PYH3_k127_7318513_7 transposition - - - 0.0000000000003766 71.0
PYH3_k127_7318513_8 Phage integrase, N-terminal SAM-like domain - - - 0.000003296 50.0
PYH3_k127_7325364_0 Homoserine dehydrogenase K00003 - 1.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 487.0
PYH3_k127_7325364_1 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 347.0
PYH3_k127_7340422_0 phosphorelay signal transduction system K07667 - - 0.00000000000000000000000000000000000000000000000000002789 196.0
PYH3_k127_7340422_1 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.00000000000000000002017 96.0
PYH3_k127_7342458_0 MFS_1 like family - - - 0.0000000000000000000000000000000000000005596 163.0
PYH3_k127_7351113_0 deoxyhypusine monooxygenase activity - - - 0.000000000000006191 81.0
PYH3_k127_7351113_1 Thioredoxin-like K06196 - - 0.00000000006247 66.0
PYH3_k127_7351113_2 periplasmic protein thiol disulfide oxidoreductases, DsbE subfamily K02199 - - 0.0000126 52.0
PYH3_k127_7361788_0 Transcriptional regulatory protein, C terminal K07667 - - 0.000000000000000000000000000000000000000000000000000000000000000000002564 242.0
PYH3_k127_7361788_1 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000007821 140.0
PYH3_k127_737944_0 Selenocysteine-specific translation elongation factor K03833 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000103 266.0
PYH3_k127_737944_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000002162 161.0
PYH3_k127_738724_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000007438 257.0
PYH3_k127_738724_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001271 256.0
PYH3_k127_738724_2 Acetyltransferase (GNAT) domain K00619 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000652 211.0
PYH3_k127_738724_3 NUDIX domain K01515 - 3.6.1.13 0.0000000000000000000000000000000000000000000000216 176.0
PYH3_k127_738724_4 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000007322 73.0
PYH3_k127_7387607_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003283 488.0
PYH3_k127_7387607_1 Putative modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000138 150.0
PYH3_k127_7418015_0 Cysteine-rich secretory protein family - - - 0.000000000000005211 80.0
PYH3_k127_7455706_0 tail specific protease K03797 - 3.4.21.102 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000215 317.0
PYH3_k127_7460342_0 Belongs to the GSP D family K02280 - - 0.00000000000000000000001017 113.0
PYH3_k127_7489675_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 413.0
PYH3_k127_7489675_1 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004727 298.0
PYH3_k127_7489675_2 periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 290.0
PYH3_k127_7513585_0 cellulose binding - - - 0.0000000000000000000000000000001248 135.0
PYH3_k127_7513585_1 - - - - 0.000000000000000000000000000001882 130.0
PYH3_k127_752481_0 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000001282 185.0
PYH3_k127_752481_1 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides - - - 0.000000001806 60.0
PYH3_k127_752481_2 Histidine kinase-like ATPases K04079 - - 0.0000000234 66.0
PYH3_k127_752481_3 MerR family regulatory protein - - - 0.0006574 46.0
PYH3_k127_7539281_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 9.997e-242 770.0
PYH3_k127_7539281_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004276 421.0
PYH3_k127_7539281_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.0000000000000000000000000000000000000000000000000000001217 200.0
PYH3_k127_7539281_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.000000000000000000000000000000000001202 141.0
PYH3_k127_7539281_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000008306 76.0
PYH3_k127_7545097_0 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 9.354e-265 823.0
PYH3_k127_7545097_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005443 538.0
PYH3_k127_7545097_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002993 462.0
PYH3_k127_7545097_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000001719 198.0
PYH3_k127_7545097_4 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000302 177.0
PYH3_k127_7545097_5 4Fe-4S dicluster domain K00171 - 1.2.7.1 0.000000000000000000000000000000000000003549 147.0
PYH3_k127_7556913_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead domain K03520,K07469,K11177 - 1.17.1.4,1.2.5.3,1.2.99.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 478.0
PYH3_k127_7556913_1 Isochorismatase family K09020 - 3.5.1.110 0.000000000000000000001435 100.0
PYH3_k127_7574605_0 sulfur carrier activity K09004 - - 0.0000000000000003844 78.0
PYH3_k127_7578640_0 PFAM Appr-1-p processing - - - 0.00000000000000000000000000000000000000000000000000000000000251 213.0
PYH3_k127_7578640_1 COG0477 Permeases of the major facilitator superfamily - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000001128 170.0
PYH3_k127_7578640_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000001084 161.0
PYH3_k127_7578640_3 4Fe-4S dicluster domain - - - 0.000000001043 59.0
PYH3_k127_7633411_0 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000271 526.0
PYH3_k127_7633411_1 Phosphoglycerate mutase family K01834 - 5.4.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002159 391.0
PYH3_k127_7633411_2 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004195 356.0
PYH3_k127_7633411_3 PQ loop repeat K15383 - - 0.00000000000002526 75.0
PYH3_k127_7667792_0 PFAM CO dehydrogenase acetyl-CoA synthase complex beta subunit K14138 - 2.3.1.169 0.0 1120.0
PYH3_k127_7667792_1 TIGRFAM Carbon-monoxide dehydrogenase, catalytic subunit K00198 - 1.2.7.4 1.35e-286 893.0
PYH3_k127_7667792_2 Putative Fe-S cluster K00197 - 2.1.1.245 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009798 561.0
PYH3_k127_7667792_3 CO dehydrogenase/acetyl-CoA synthase delta subunit K00194 - 2.1.1.245 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001481 433.0
PYH3_k127_7667792_4 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004115 378.0
PYH3_k127_7667792_5 Pterin binding enzyme K15023 - 2.1.1.258 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009898 350.0
PYH3_k127_7667792_6 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000003513 138.0
PYH3_k127_7667792_7 - - - - 0.000108 48.0
PYH3_k127_7680353_0 4Fe-4S ferredoxin, iron-sulfur binding K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 557.0
PYH3_k127_7680353_1 PFAM Methylene-tetrahydrofolate reductase C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000204 276.0
PYH3_k127_7680353_2 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.00000000000000000000000000000000000000000000000000007244 189.0
PYH3_k127_7680353_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000005883 190.0
PYH3_k127_7680353_4 Methylenetetrahydrofolate reductase - - - 0.0000000000002325 72.0
PYH3_k127_7683103_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 469.0
PYH3_k127_7683103_1 Receptor family ligand binding region K01999 - - 0.000000000000000001163 89.0
PYH3_k127_7683103_2 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000008113 77.0
PYH3_k127_7693269_0 integral membrane protein - - - 0.0000000000000000000000000000000000002949 151.0
PYH3_k127_7693269_1 protein phosphatase 2C domain protein K20074 - 3.1.3.16 0.0002377 46.0
PYH3_k127_7701_0 ACT domain K00928 - 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 569.0
PYH3_k127_7701_1 Metalloenzyme superfamily K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000974 503.0
PYH3_k127_7701_2 TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000101 200.0
PYH3_k127_7706825_0 Telomere recombination K04656 - - 1.373e-271 856.0
PYH3_k127_7706825_1 Hydrogenase formation hypA family K04654 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 393.0
PYH3_k127_7706825_2 acetyl-CoA hydrolase K18122 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006095 379.0
PYH3_k127_7706825_3 PFAM DegV family protein - - - 0.000000000000000000000000000000004089 139.0
PYH3_k127_7706825_4 hydrogenase assembly chaperone HypC HupF K04653 - - 0.000000000000000004345 85.0
PYH3_k127_7710907_0 Chagasin family peptidase inhibitor I42 K14475 - - 0.00000000000002255 79.0
PYH3_k127_7710907_1 Pyrrolo-quinoline quinone - - - 0.000025 48.0
PYH3_k127_7720380_0 TIGRFAM zinc-binding alcohol dehydrogenase family protein K13953 - 1.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000006727 266.0
PYH3_k127_7720380_1 Trypsin - - - 0.0000000000000000634 87.0
PYH3_k127_7720380_2 Belongs to the phosphoglycerate mutase family K22305 - 3.1.3.3 0.0006044 48.0
PYH3_k127_7728828_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000269 354.0
PYH3_k127_7728828_1 AAA domain K07321 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005129 311.0
PYH3_k127_7728828_2 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 311.0
PYH3_k127_7728828_3 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000001864 125.0
PYH3_k127_7738156_0 Participates in both transcription termination and antitermination K02600 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009246 508.0
PYH3_k127_7738156_1 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006041 464.0
PYH3_k127_7738156_2 Protein of unknown function (DUF448) K07742 - - 0.00000000000000000000176 96.0
PYH3_k127_7846012_0 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000000000000001371 212.0
PYH3_k127_7862834_0 PFAM ApbE family K09740 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000782 256.0
PYH3_k127_7862834_1 NIL - - - 0.00000000000000000000000000000000000000000000000000000001254 200.0
PYH3_k127_7862834_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000001044 129.0
PYH3_k127_7862834_3 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000000003522 123.0
PYH3_k127_7880786_0 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity K01814 GO:0000105,GO:0003674,GO:0003824,GO:0003949,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005197 296.0
PYH3_k127_7880786_1 PFAM isochorismatase hydrolase - - - 0.00000000000000000000000000000000000000000000000000000005003 201.0
PYH3_k127_7880786_2 Protein of unknown function (DUF1385) K09153 - - 0.000000000000000000000000000000000000000000000002769 176.0
PYH3_k127_7880786_3 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 - 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000002601 156.0
PYH3_k127_7880786_4 acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01966 - 2.1.3.15,6.4.1.3 0.000000000000000001453 87.0
PYH3_k127_788756_0 Pfam:Kce K18013 - 2.3.1.247 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 363.0
PYH3_k127_788756_1 Dehydrogenase K00074 - 1.1.1.157 0.00000000000000000000000000000000000000000000000000000008655 197.0
PYH3_k127_788756_2 Serine aminopeptidase, S33 - - - 0.0000000000000000000000001384 108.0
PYH3_k127_788756_3 Serine aminopeptidase, S33 K01048 GO:0001906,GO:0001907,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006629,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0010941,GO:0010942,GO:0016020,GO:0016042,GO:0016298,GO:0016787,GO:0016788,GO:0030312,GO:0031341,GO:0031343,GO:0031640,GO:0035821,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043900,GO:0043902,GO:0043903,GO:0044003,GO:0044004,GO:0044068,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044364,GO:0044403,GO:0044419,GO:0044464,GO:0044531,GO:0044532,GO:0044533,GO:0046486,GO:0046503,GO:0047372,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051701,GO:0051704,GO:0051709,GO:0051712,GO:0051817,GO:0051818,GO:0051883,GO:0052040,GO:0052042,GO:0052150,GO:0052151,GO:0052248,GO:0052330,GO:0052433,GO:0052501,GO:0052689,GO:0065007,GO:0071704,GO:0071944,GO:1901575 3.1.1.5 0.0000000000000000000001115 100.0
PYH3_k127_788756_4 Alpha/beta hydrolase family - GO:0003674,GO:0003824,GO:0005575,GO:0006629,GO:0008150,GO:0008152,GO:0016020,GO:0016298,GO:0016787,GO:0016788,GO:0044238,GO:0071704 - 0.00000000002275 64.0
PYH3_k127_7887798_0 Dak1_2 K07030 - - 0.000000000000000000000000000000000000000000000000000000000006496 214.0
PYH3_k127_7887798_1 Dodecin K09165 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000001187 57.0
PYH3_k127_78900_0 GYD domain - - - 0.000000000000000000000000000003713 122.0
PYH3_k127_78900_1 Universal stress protein family - - - 0.000000000003055 72.0
PYH3_k127_7901611_0 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000035 262.0
PYH3_k127_7901611_1 Major Facilitator Superfamily - - - 0.0000000000005787 73.0
PYH3_k127_7914377_0 PFAM Formylglycine-generating sulfatase enzyme - - - 0.000000000000000000000000000000004348 145.0
PYH3_k127_7914377_1 Oxygen-independent coproporphyrinogen III oxidase - - - 0.0001951 44.0
PYH3_k127_7919565_0 Homocysteine biosynthesis enzyme, sulfur-incorporation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001014 605.0
PYH3_k127_7919565_1 Domain of unknown function (DUF362) - - - 0.000000000000000000523 94.0
PYH3_k127_7956726_0 PFAM SMP-30 Gluconolaconase LRE-like region K01053 - 3.1.1.17 0.00000000000000000000000000000000000000000000000000000003086 217.0
PYH3_k127_7956726_1 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000007535 94.0
PYH3_k127_7956726_2 Phosphatidylethanolamine-binding protein K06910 - - 0.00000000001108 74.0
PYH3_k127_7970506_0 Belongs to the peptidase M50B family - - - 0.00000000000000000000000000000000000000000000002349 176.0
PYH3_k127_7970506_1 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000007023 130.0
PYH3_k127_7992432_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000001148 115.0
PYH3_k127_7992432_1 transposition K07497 - - 0.00000000000000000000000145 105.0
PYH3_k127_8001360_0 prohibitin homologues - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008307 259.0
PYH3_k127_8001360_1 4Fe-4S dicluster domain K00184 - - 0.0000000000000000000000000000000000000000000000000006152 195.0
PYH3_k127_8023761_0 pathogenesis - - - 0.0000000000000001579 82.0
PYH3_k127_8023761_1 cellulase activity K12567 - 2.7.11.1 0.000000000004023 77.0
PYH3_k127_8023761_2 Domain of unknown function (DUF4382) - - - 0.0000003616 55.0
PYH3_k127_8023761_3 Cystathionine beta-lyase K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.00001384 56.0
PYH3_k127_8051873_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004601 391.0
PYH3_k127_8051873_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000003777 216.0
PYH3_k127_8056356_0 PFAM Pyridoxal-5'-phosphate-dependent protein beta subunit K01697,K01738,K12339 - 2.5.1.47,4.2.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007429 324.0
PYH3_k127_8056356_1 Uncharacterised protein, DegV family COG1307 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003538 299.0
PYH3_k127_8060578_0 Yqey-like protein K09117 - - 0.00000000000000000000000000000001147 132.0
PYH3_k127_8060578_1 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.000000000000003584 75.0
PYH3_k127_8060578_2 Ribosomal protein S21 K02970 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000004509 76.0
PYH3_k127_8060578_3 Myo-inositol-1-phosphate synthase K01858 - 5.5.1.4 0.00000000000003656 73.0
PYH3_k127_8071065_0 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009899 386.0
PYH3_k127_8071065_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01840 - 5.4.2.8 0.00000000000000000000000000000000000000001149 156.0
PYH3_k127_8115843_0 PFAM Bile acid sodium symporter K03325 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001132 484.0
PYH3_k127_8115843_1 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001853 346.0
PYH3_k127_8115843_2 PFAM Methyltransferase type 11 K07755 - 2.1.1.137 0.0000000000000000000000000000000000000000000000002222 184.0
PYH3_k127_8115843_3 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000007822 96.0
PYH3_k127_811710_0 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K13829 - 2.7.1.71,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 329.0
PYH3_k127_811710_1 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 - 1.1.1.25 0.000000000000000000000000000000000000000000000000000000000003367 216.0
PYH3_k127_811710_2 Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate K03785 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000006798 197.0
PYH3_k127_8118848_0 NADH ubiquinone oxidoreductase, NADH-binding K00124,K00335,K18331 - 1.12.1.3,1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 499.0
PYH3_k127_8118848_1 Iron hydrogenase small subunit K00123,K00336,K18332 - 1.12.1.3,1.17.1.9,1.6.5.3 0.00000000000000000000000000000000000000000000981 171.0
PYH3_k127_8118848_2 nitrite transmembrane transporter activity K02575,K10850 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000005759 63.0
PYH3_k127_8131182_0 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000004443 107.0
PYH3_k127_8131182_1 Helix-turn-helix domain - - - 0.000000006023 57.0
PYH3_k127_813227_0 - - - - 0.000000000000112 71.0
PYH3_k127_813227_1 PFAM PEBP family protein K06910 - - 0.0000000123 64.0
PYH3_k127_8142556_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 544.0
PYH3_k127_8142556_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 500.0
PYH3_k127_8142556_2 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005365 478.0
PYH3_k127_8142556_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 321.0
PYH3_k127_8142556_4 ABC-2 family transporter protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004524 300.0
PYH3_k127_8142556_5 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006951 274.0
PYH3_k127_8142556_6 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000289 156.0
PYH3_k127_8142556_7 PFAM Uncharacterised protein, DegV family COG1307 - GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000002925 128.0
PYH3_k127_8142556_8 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000001206 111.0
PYH3_k127_8142556_9 ATP binding cassette transporter ABC protein K01990 - - 0.0002646 46.0
PYH3_k127_8182927_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K03885,K15977 - 1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001265 288.0
PYH3_k127_8182927_1 PFAM adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.00000000000000000000000000000000000000000000000005171 194.0
PYH3_k127_8206125_0 histidine kinase, HAMP K02482 - 2.7.13.3 0.000000000000000000000000000000000000000000000000127 184.0
PYH3_k127_8206125_1 Cupin domain - - - 0.00000000003892 69.0
PYH3_k127_8238137_0 belongs to the thioredoxin family K20444,K20543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009767 306.0
PYH3_k127_8238137_1 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain and a metal-binding domain - - - 0.00007439 46.0
PYH3_k127_8285092_0 tyrosine recombinase XerC K03733,K04763 - - 0.00000000000000000000000000000001291 141.0
PYH3_k127_8286236_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006365 328.0
PYH3_k127_8286236_1 ABC transporter permease K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 289.0
PYH3_k127_8286236_2 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000006955 146.0
PYH3_k127_8286695_0 Iron-sulfur cluster-binding protein K00782 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002045 476.0
PYH3_k127_8286695_1 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009726 355.0
PYH3_k127_8286695_2 4Fe-4S ferredoxin iron-sulfur binding domain protein K11473 - - 0.000000000000000000000000000000000000000000000000000002406 203.0
PYH3_k127_8308395_0 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006814 349.0
PYH3_k127_8309995_0 Peptidase dimerisation domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001766 441.0
PYH3_k127_8309995_1 BadF BadG BcrA BcrD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 420.0
PYH3_k127_8309995_10 Lrp/AsnC ligand binding domain - - - 0.000000000000000000007743 94.0
PYH3_k127_8309995_11 4-oxalocrotonate tautomerase K01821 - 5.3.2.6 0.00000000000001334 76.0
PYH3_k127_8309995_2 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001215 392.0
PYH3_k127_8309995_3 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004308 343.0
PYH3_k127_8309995_4 PFAM CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 342.0
PYH3_k127_8309995_5 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001568 310.0
PYH3_k127_8309995_6 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007777 295.0
PYH3_k127_8309995_7 CoA enzyme activase uncharacterised domain (DUF2229) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002047 270.0
PYH3_k127_8309995_8 Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS K08681 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006081,GO:0006725,GO:0006732,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0009058,GO:0009108,GO:0009110,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0042822,GO:0042823,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046184,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617,GO:1902494,GO:1903600 4.3.3.6 0.000000000000000000000000000000000000000000000000000000000000002325 222.0
PYH3_k127_8309995_9 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000004867 139.0
PYH3_k127_8356159_0 Iron-containing alcohol dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000004185 226.0
PYH3_k127_8356159_1 Fumarate reductase flavoprotein C-term K00278 - 1.4.3.16 0.000001963 51.0
PYH3_k127_8380919_0 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005114 587.0
PYH3_k127_838576_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001003 560.0
PYH3_k127_838576_1 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003808 321.0
PYH3_k127_8403891_0 X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain K06978 - - 9.414e-221 699.0
PYH3_k127_8403891_1 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.0000000000000000000000003544 106.0
PYH3_k127_8444773_0 Haemolysin-type calcium-binding repeat (2 copies) - - - 0.0000000000000000000000000000000000000000000000000000000000000005121 231.0
PYH3_k127_8444773_1 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000001984 151.0
PYH3_k127_8444773_2 META domain protein - - - 0.00000000000879 76.0
PYH3_k127_8455090_0 Psort location CytoplasmicMembrane, score K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.000000000000003133 81.0
PYH3_k127_8455090_1 4-amino-4-deoxy-L-arabinose transferase activity - - - 0.000001162 60.0
PYH3_k127_8460849_0 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 557.0
PYH3_k127_8478968_0 acid phosphatase activity - - - 0.00000000000000000000000000000000000000006027 158.0
PYH3_k127_8478968_1 phosphatase K01113 - 3.1.3.1 0.0004606 51.0
PYH3_k127_8488785_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 320.0
PYH3_k127_8488785_1 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001802 308.0
PYH3_k127_8488785_2 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000003866 169.0
PYH3_k127_8565648_0 methyltransferase activity - - - 0.000000000000000000000000000003836 128.0
PYH3_k127_8573664_0 Bacterial extracellular solute-binding proteins, family 5 Middle K15580 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 513.0
PYH3_k127_8573664_1 Peptidase MA superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000454 285.0
PYH3_k127_8573664_2 Domain of unknown function (DUF296) K06934 - - 0.00000004642 60.0
PYH3_k127_8590510_0 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003349 385.0
PYH3_k127_8590510_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 0.00000000000000000000000000000000000000000000000001859 183.0
PYH3_k127_8590510_2 - - - - 0.0006797 48.0
PYH3_k127_8643346_0 CobW/HypB/UreG, nucleotide-binding domain K04652 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000355 250.0
PYH3_k127_8643346_1 hydrogenase expression formation protein HypE K04655 - - 0.0000000000000000000000000000000000000000000000000000004252 196.0
PYH3_k127_8643346_2 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000008294 137.0
PYH3_k127_8643346_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00000000000000000000000002375 111.0
PYH3_k127_8667473_0 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 1.938e-223 703.0
PYH3_k127_8667473_1 Aminotransferase class-V - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007328 464.0
PYH3_k127_8667473_2 Protein of unknown function (DUF1015) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000443 433.0
PYH3_k127_8667473_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.0000000000000000000000000000000000000000000000000000005008 198.0
PYH3_k127_8669534_0 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004732 423.0
PYH3_k127_8669534_1 endonuclease III - - - 0.00000000000000000000000000000000000000000000000000000000000002364 222.0
PYH3_k127_8669534_2 Amidohydrolase K22213 - 4.1.1.52 0.0000000000000002262 91.0
PYH3_k127_8713124_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1079.0
PYH3_k127_8713124_1 Elongator protein 3, MiaB family, Radical SAM - - - 1.164e-220 700.0
PYH3_k127_8713124_3 TPR repeat - - - 0.0006879 45.0
PYH3_k127_874139_0 NADH oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008806 374.0
PYH3_k127_874139_1 MmgE/PrpD family - - - 0.000000000000000000000005349 116.0
PYH3_k127_874139_2 hmm pf01266 K00244 - 1.3.5.4 0.00000000000002188 75.0
PYH3_k127_877327_0 peptidase, M24 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003141 255.0
PYH3_k127_877327_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000199 129.0
PYH3_k127_877327_2 PFAM D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000001979 62.0
PYH3_k127_8782278_0 ABC transporter substrate-binding protein - - - 0.00000000000000000000000000000000000000000000009957 188.0
PYH3_k127_8782278_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000001048 61.0
PYH3_k127_8784756_0 Arylsulfotransferase (ASST) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003291 327.0
PYH3_k127_8784756_1 Arylsulfotransferase (ASST) - - - 0.00000000000000000000000000000000000000000000000000000000000001731 233.0
PYH3_k127_8784756_2 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000002837 230.0
PYH3_k127_8784756_3 COG1520 FOG WD40-like repeat - - - 0.0000000000000000000000000000000000000000000004328 183.0
PYH3_k127_8872985_0 ABC transporter substrate-binding protein K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000003988 242.0
PYH3_k127_8882919_0 PFAM Formate--tetrahydrofolate ligase K01938 - 6.3.4.3 1.47e-198 622.0
PYH3_k127_8882919_1 PFAM CobQ CobB MinD ParA nucleotide binding domain K07321 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000037 296.0
PYH3_k127_8921316_0 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 290.0
PYH3_k127_8921316_1 TIGRFAM HAD-superfamily hydrolase, subfamily IA, variant 3 K01838 - 5.4.2.6 0.00000000000000000000000000000000000000000000000003083 192.0
PYH3_k127_8921316_2 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000000000004476 178.0
PYH3_k127_8921316_3 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 GO:0003674,GO:0003824,GO:0004550,GO:0006139,GO:0006165,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009117,GO:0009132,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0019205,GO:0019637,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046939,GO:0055086,GO:0071704,GO:1901360 2.7.4.6 0.00000000000000000000000000000000000000000000004747 172.0
PYH3_k127_8921316_4 PFAM peptidase M22 glycoprotease K14742 - - 0.00000000000000000000000000000000000000000000157 174.0
PYH3_k127_8921316_5 Thioesterase superfamily - - - 0.000000000000000000000005495 114.0
PYH3_k127_8921316_6 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000002939 65.0
PYH3_k127_8925717_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 321.0
PYH3_k127_8925717_1 Belongs to the D-alanine--D-alanine ligase family K01921,K01955 - 6.3.2.4,6.3.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002388 285.0
PYH3_k127_8929215_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 1.642e-242 764.0
PYH3_k127_8929215_1 Putative exonuclease SbcCD, C subunit K03546 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007345 359.0
PYH3_k127_8929215_2 B12 binding domain - - - 0.000000008114 61.0
PYH3_k127_8932795_0 COG1173 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008711 298.0
PYH3_k127_8932795_1 ABC transporter permease K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005012 295.0
PYH3_k127_8932795_2 Bacterial extracellular solute-binding proteins, family 5 Middle - - - 0.00000000000000000919 92.0
PYH3_k127_8955297_0 Phosphatidylethanolamine-binding protein K06910 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044424,GO:0044464 - 0.000000006679 63.0
PYH3_k127_8956548_0 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000000000000000000002915 209.0
PYH3_k127_8956548_1 Phosphohydrolase-associated domain K01129 - 3.1.5.1 0.00000000000000000000000000000000000000000000000000000001354 203.0
PYH3_k127_8970961_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003939 576.0
PYH3_k127_8970961_1 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 300.0
PYH3_k127_8970961_2 phosphoribosylanthranilate isomerase activity K01817 - 5.3.1.24 0.000000000000000000000000000000000000000000000000000000000461 209.0
PYH3_k127_8970961_3 Elongation factor G, domain IV K02355 - - 0.00000000000000000000000000005874 117.0
PYH3_k127_8975526_0 ferroxidase activity K03594 GO:0003674,GO:0003824,GO:0004322,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006873,GO:0006875,GO:0006879,GO:0008150,GO:0008152,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0016020,GO:0016491,GO:0016722,GO:0016724,GO:0019725,GO:0030003,GO:0033212,GO:0033214,GO:0042221,GO:0042592,GO:0044424,GO:0044444,GO:0044464,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0055065,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055114,GO:0065007,GO:0065008,GO:0071944,GO:0098771 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000001471 212.0
PYH3_k127_8975526_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000001329 87.0
PYH3_k127_8975526_2 YHYH protein - - - 0.00000000000000006177 87.0
PYH3_k127_8977920_0 4fe-4S ferredoxin, iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 347.0
PYH3_k127_8977920_1 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.00000000000001271 74.0
PYH3_k127_8992092_0 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002049 331.0
PYH3_k127_8992092_1 Pfam SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000002156 181.0
PYH3_k127_8992092_2 MerR HTH family regulatory protein K13640 - - 0.000000000000000000000000000001313 123.0
PYH3_k127_8992092_3 Methyltransferase type 11 - - - 0.0000000000000001254 87.0
PYH3_k127_8996302_0 Type II secretion system (T2SS), protein F K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000219 363.0
PYH3_k127_9010466_0 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.00000000000000000000000000000000000001723 147.0
PYH3_k127_9010466_1 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0005886,GO:0015934,GO:0016020,GO:0022625,GO:0022626,GO:0030312,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071944,GO:1990904 - 0.000000000002674 72.0
PYH3_k127_9010466_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.0001207 47.0
PYH3_k127_9036386_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004654,GO:0005488,GO:0006139,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0019439,GO:0034641,GO:0034655,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575 2.7.7.8 3.62e-265 836.0
PYH3_k127_9036386_1 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 288.0
PYH3_k127_9036386_2 haloacid dehalogenase-like hydrolase K08966 - 3.1.3.87 0.000000000000000000000000000000000000000000000000000000000000000136 227.0
PYH3_k127_9036386_3 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000002691 229.0
PYH3_k127_9036386_4 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.0000000000000000000000000000000000000000004907 160.0
PYH3_k127_9036386_5 Mut7-C RNAse domain K09122 - - 0.00000000000000000000000000000000726 134.0
PYH3_k127_9036386_6 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000006147 106.0
PYH3_k127_9042217_0 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002725 286.0
PYH3_k127_9042217_1 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.0000000000000000000001381 99.0
PYH3_k127_9062964_0 SERine Proteinase INhibitors K13963 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 462.0
PYH3_k127_9072587_0 Domain of unknown function (DUF2437) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003603 279.0
PYH3_k127_9072587_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
PYH3_k127_9072587_2 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.00003487 47.0
PYH3_k127_9098243_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001082 312.0
PYH3_k127_9098243_1 Protein of unknown function (DUF1464) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003046 297.0
PYH3_k127_9098243_2 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000008082 134.0
PYH3_k127_9130036_0 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 339.0
PYH3_k127_9130036_1 Belongs to the sulfur carrier protein TusA family - - - 0.00000006736 56.0
PYH3_k127_9157917_0 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005674 374.0
PYH3_k127_9157917_1 Radical SAM domain protein K04070 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000002724 230.0
PYH3_k127_9157917_2 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation - - - 0.0000000000000000016 86.0
PYH3_k127_9157917_3 - - - - 0.0006968 44.0
PYH3_k127_9194553_0 PAC2 family K07159 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001597 289.0
PYH3_k127_9194553_1 - - - - 0.000000000000000000000000000000000000000000000000006719 192.0
PYH3_k127_9194553_2 GtrA-like protein K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000006771 176.0
PYH3_k127_9194553_3 PAC2 family - - - 0.00000000000000000000000000000000000000001079 165.0
PYH3_k127_9198380_0 Cytochrome c K02030 - - 0.0000000000000000000009963 100.0
PYH3_k127_9198380_1 Gluconate 2-dehydrogenase subunit 3 K06152 - 1.1.99.3 0.000000004635 63.0
PYH3_k127_920441_0 B12 binding domain - - - 1.341e-196 623.0
PYH3_k127_920441_1 RNA recognition motif - - - 0.00000000000000005802 83.0
PYH3_k127_920441_2 Probable zinc-ribbon domain - - - 0.0000000000000002615 82.0
PYH3_k127_920441_3 extracellular solute-binding protein, family 1 K05772 - - 0.00000001262 56.0
PYH3_k127_9215482_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1074.0
PYH3_k127_9215482_1 Catalyzes the attachment of glycine to tRNA(Gly) K01880 - 6.1.1.14 9.685e-213 669.0
PYH3_k127_9215482_2 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001661 524.0
PYH3_k127_9215482_3 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000288 408.0
PYH3_k127_9215482_4 lysyl-tRNA aminoacylation K04567 - 6.1.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000002265 261.0
PYH3_k127_9215482_5 Divergent PAP2 family K09775 - - 0.00000000000000000000000000000002846 130.0
PYH3_k127_9215482_6 - - - - 0.000000000000000000001151 102.0
PYH3_k127_921765_0 Pyridoxal-phosphate dependent enzyme K01738 - 2.5.1.47 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002694 494.0
PYH3_k127_921765_1 PFAM Cys Met metabolism, pyridoxal phosphate-dependent enzyme K01760 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 485.0
PYH3_k127_921765_2 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008824 458.0
PYH3_k127_921765_3 Dak1_2 K07030 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006045 343.0
PYH3_k127_921765_4 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000002976 224.0
PYH3_k127_921765_5 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000001319 200.0
PYH3_k127_921765_6 denitrification pathway - - - 0.000000000000000000000000000000000000000000000008928 181.0
PYH3_k127_921765_7 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000001823 165.0
PYH3_k127_921765_8 Carboxylesterase family - - - 0.000000000000000000000000000000000000000005591 160.0
PYH3_k127_921765_9 methionine transport K02071 - - 0.0000000000000002594 81.0
PYH3_k127_9259123_0 Histidine kinase K07777 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001196 288.0
PYH3_k127_9259123_1 PFAM Response regulator receiver domain K02479 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000158 247.0
PYH3_k127_9259123_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000004948 168.0
PYH3_k127_9259123_3 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000004501 111.0
PYH3_k127_9286787_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00394 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009307 292.0
PYH3_k127_9286787_1 amidohydrolase - - - 0.000000000000000000000000006594 118.0
PYH3_k127_9288798_0 Family of unknown function (DUF5343) - - - 0.000000000000000000000000000000000000000000000000000000000000001231 224.0
PYH3_k127_9288798_1 Type II/IV secretion system protein K02669 - - 0.000000000000000005056 85.0
PYH3_k127_9315022_0 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008947 438.0
PYH3_k127_9315022_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K10823 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002302 418.0
PYH3_k127_9348801_0 glycyl-radical enzyme activating protein family K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001374 317.0
PYH3_k127_9348801_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.0008002 42.0
PYH3_k127_9359488_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 601.0
PYH3_k127_9359488_1 Aminotransferase class-V K00830,K00839 GO:0001505,GO:0003674,GO:0003824,GO:0004760,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005777,GO:0006082,GO:0006520,GO:0006544,GO:0006545,GO:0006807,GO:0008150,GO:0008152,GO:0008453,GO:0008483,GO:0008652,GO:0009058,GO:0009069,GO:0009070,GO:0009987,GO:0016053,GO:0016740,GO:0016769,GO:0017144,GO:0019265,GO:0019752,GO:0042133,GO:0042136,GO:0042579,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0065007,GO:0065008,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.6.1.112,2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009395 323.0
PYH3_k127_9367045_0 Uncharacterised MFS-type transporter YbfB - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001111 298.0
PYH3_k127_9367045_1 Glutamine cyclotransferase K00683 - 2.3.2.5 0.000000000000000000000000000000000000000000000000000000000000000000001578 241.0
PYH3_k127_9367045_2 peroxiredoxin activity K01607 - 4.1.1.44 0.0000000000000006474 81.0
PYH3_k127_9403428_0 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000107 500.0
PYH3_k127_9403428_1 Domain of unknown function (DUF4389) - - - 0.000000000000000000003713 98.0
PYH3_k127_9403428_2 Protease prsW family - - - 0.0001203 51.0
PYH3_k127_9461764_0 Aldo/keto reductase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003731 308.0
PYH3_k127_9461764_1 ABC-type antimicrobial peptide transport system, ATPase component K02003 - - 0.0000000000000000000000000000000000000000000000000000000000001201 220.0
PYH3_k127_9461764_2 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000003236 77.0
PYH3_k127_9472326_0 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 520.0
PYH3_k127_9472326_1 TIGRFAM sodium ion-translocating decarboxylase, beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002099 454.0
PYH3_k127_9472326_2 D-isomer specific 2-hydroxyacid dehydrogenase K12972 - 1.1.1.79,1.1.1.81 0.000000000000000000000000000000000000000000000000000000000000005368 229.0
PYH3_k127_9472326_3 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000002615 161.0
PYH3_k127_9472326_4 Cytidylate kinase-like family - - - 0.0000000000000000002042 96.0
PYH3_k127_947251_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 8.639e-301 947.0
PYH3_k127_947251_1 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 499.0
PYH3_k127_947251_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:1901564 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005915 454.0
PYH3_k127_947251_3 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007492 348.0
PYH3_k127_947251_4 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 332.0
PYH3_k127_947251_5 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003168 301.0
PYH3_k127_947251_6 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004153 278.0
PYH3_k127_947251_7 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.0000000000000000000000000000000000000000000000000000000000000004277 225.0
PYH3_k127_947251_8 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.000000000000000000000000000000000000000000000000000009077 193.0
PYH3_k127_947251_9 Transporter of a GTP-driven Fe(2 ) uptake system - - - 0.00000000000000000000000000000000000000000000000002818 189.0
PYH3_k127_9487553_0 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006936 291.0
PYH3_k127_9487553_1 beta-keto acid cleavage enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000001723 241.0
PYH3_k127_9487553_2 Enoyl-(Acyl carrier protein) reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000006399 228.0
PYH3_k127_9487553_3 coenzyme F420 binding K00275 - 1.4.3.5 0.00000000000000000000000000001165 123.0
PYH3_k127_9487553_4 Ferritin-like domain K03594 - 1.16.3.1 0.000000005419 57.0
PYH3_k127_9498656_0 NapC/NirT cytochrome c family, N-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002208 313.0
PYH3_k127_9524930_0 cation diffusion facilitator family transporter K16264 - - 0.000000000000000001073 90.0
PYH3_k127_9524930_1 Belongs to the 'phage' integrase family - - - 0.0000000002618 61.0
PYH3_k127_9575072_0 ATP-grasp domain K22224 - 6.2.1.13 0.000000000000000000000000000000000000000000000000000000000000000000002674 242.0
PYH3_k127_9575072_1 PFAM CoA-binding domain protein - - - 0.000000000003094 75.0
PYH3_k127_9578688_0 COG2414 Aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003835 490.0
PYH3_k127_9578688_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000112 357.0
PYH3_k127_9578688_2 conserved protein (DUF2088) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008137 293.0
PYH3_k127_9578688_3 Belongs to the LDH MDH superfamily. LDH family K00016,K00024 - 1.1.1.27,1.1.1.37 0.00000000000000000000000000000001502 134.0
PYH3_k127_9578688_4 Tetratricopeptide repeat - - - 0.0000000000000000000005841 100.0
PYH3_k127_9578688_5 - - - - 0.000000000002367 70.0
PYH3_k127_9578688_6 Isochorismatase family - - - 0.000002983 57.0
PYH3_k127_9578688_7 PFAM Protein kinase domain - - - 0.000025 48.0
PYH3_k127_9591084_0 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000005165 198.0
PYH3_k127_9591084_1 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000004866 162.0
PYH3_k127_9609492_0 FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 467.0
PYH3_k127_9609492_1 PFAM Methylenetetrahydrofolate reductase K00297,K00547 - 1.5.1.20,2.1.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001281 362.0
PYH3_k127_9609492_2 Methylene-tetrahydrofolate reductase C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000000009606 241.0
PYH3_k127_9609492_3 Enoyl-CoA hydratase/isomerase K15866,K18474 GO:0003674,GO:0003824,GO:0004300,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0006635,GO:0006636,GO:0008150,GO:0008152,GO:0008610,GO:0009056,GO:0009058,GO:0009062,GO:0009987,GO:0016042,GO:0016053,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016853,GO:0016860,GO:0016863,GO:0019395,GO:0019752,GO:0030258,GO:0032787,GO:0033559,GO:0034017,GO:0034440,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0055114,GO:0071704,GO:0072329,GO:0072330,GO:1901575,GO:1901576 5.3.3.14,5.3.3.18 0.000000000000000000000000000000000000000000000000000000000376 211.0
PYH3_k127_9609492_4 Response regulator receiver - - - 0.000000000000000000000000000000000000000000000000000000006351 205.0
PYH3_k127_9609492_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000000000000000000000000000002697 199.0
PYH3_k127_9609492_6 helix_turn_helix, Lux Regulon K11618 - - 0.0000000000000000000000000000003161 134.0
PYH3_k127_9616434_0 GTP cyclohydrolase I activity K01495 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002695 274.0
PYH3_k127_9616434_1 ABC-2 family transporter protein - - - 0.000000000000248 75.0
PYH3_k127_9633607_0 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001499 255.0
PYH3_k127_9633607_1 cell division ATP-binding protein FtsE K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000007751 240.0
PYH3_k127_9633607_2 Part of the ABC transporter FtsEX involved in asymmetric cellular division facilitating the initiation of sporulation K09811 - - 0.000000000000004287 83.0
PYH3_k127_9693774_0 domain protein - - - 0.0000000002008 73.0
PYH3_k127_9693774_1 cellulase activity - - - 0.00004701 55.0
PYH3_k127_9696128_0 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002787 390.0
PYH3_k127_9696128_1 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000001211 60.0
PYH3_k127_971633_0 ABC transporter substrate-binding protein K02035 - - 0.0000000000000000000000000000000000000000000000002238 195.0
PYH3_k127_9743787_0 ATPase associated with various cellular activities, AAA_5 K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003543 388.0
PYH3_k127_9743787_1 Protein of unknown function DUF58 - - - 0.000000000628 66.0
PYH3_k127_9744401_0 PFAM fumarate reductase succinate dehydrogenase flavoprotein domain protein K00244 - 1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000009746 272.0
PYH3_k127_975323_0 SNARE associated Golgi protein - - - 0.00000000000000000000000000000000000000000000000000000000000000001858 230.0
PYH3_k127_975323_1 Belongs to the phosphoglycerate kinase family K00927,K01803 - 2.7.2.3,5.3.1.1 0.00000000000000000000000000000000000000000000000000000000000005954 219.0
PYH3_k127_9765972_0 Fructose-bisphosphate aldolase class-II - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001938 383.0
PYH3_k127_9765972_1 Transmembrane secretion effector - - - 0.000000000000000000000000000000000000000000000004918 188.0
PYH3_k127_9765972_2 - K03975 - - 0.00000000000000000000000000000000006515 143.0
PYH3_k127_996794_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 1.639e-197 631.0
PYH3_k127_996794_1 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000001044 241.0
PYH3_k127_998916_0 electron transfer flavoprotein, alpha subunit K03522,K22432 - 1.3.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007327 289.0