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Overview

ID MAG03227
Name PYH3_bin.32
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Pseudomonadota
Class Gammaproteobacteria
Order Burkholderiales
Family SG8-39
Genus 2-02-FULL-66-14
Species
Assembly information
Completeness (%) 88.3
Contamination (%) 5.84
GC content (%) 68.0
N50 (bp) 8,482
Genome size (bp) 3,107,891

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes3327

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1011329_0 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007499 293.0
PYH3_k127_1011329_1 ABC-type uncharacterized transport system - - - 0.00000000000000000000000000000000000000000000000000000000000000009654 232.0
PYH3_k127_1011329_2 ABC transporter, ATP-binding protein K01990 - - 0.00006763 47.0
PYH3_k127_1035885_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1177.0
PYH3_k127_1035885_1 SNARE associated Golgi protein - - - 0.0 1022.0
PYH3_k127_1035885_2 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002156 545.0
PYH3_k127_1035885_3 PFAM Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005214 468.0
PYH3_k127_1035885_4 PFAM ATPase family associated with various cellular activities (AAA) K01338 - 3.4.21.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007216 411.0
PYH3_k127_1035885_5 Protein of unknown function, DUF547 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004015 301.0
PYH3_k127_1035885_6 PFAM NUDIX hydrolase K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000005935 208.0
PYH3_k127_1035885_7 membrane transporter protein K07090 - - 0.000000000000000000000000000000000000000001852 177.0
PYH3_k127_1035885_8 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000001605 137.0
PYH3_k127_1048998_0 Hydantoinase B/oxoprolinase - - - 1.08e-286 891.0
PYH3_k127_1048998_1 Hydantoinase/oxoprolinase - - - 9.002e-277 876.0
PYH3_k127_1048998_10 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 310.0
PYH3_k127_1048998_11 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001285 296.0
PYH3_k127_1048998_12 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001464 303.0
PYH3_k127_1048998_13 NADH dehydrogenase NAD(P)H nitroreductase K09019 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004046 274.0
PYH3_k127_1048998_14 ABC transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004091 274.0
PYH3_k127_1048998_15 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002569 272.0
PYH3_k127_1048998_16 phenazine biosynthesis protein PhzF family K06998 - 5.3.3.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000005422 271.0
PYH3_k127_1048998_17 Flavodoxin domain K00230 - 1.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000005523 247.0
PYH3_k127_1048998_18 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003108 247.0
PYH3_k127_1048998_19 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000003212 248.0
PYH3_k127_1048998_2 AMP-binding enzyme C-terminal domain K00666 - - 5.707e-227 715.0
PYH3_k127_1048998_20 PFAM Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000006298 237.0
PYH3_k127_1048998_21 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000002079 169.0
PYH3_k127_1048998_22 ABC-type transport auxiliary lipoprotein component K18480 - - 0.00000000000000000000000000000000000001829 162.0
PYH3_k127_1048998_23 - - - - 0.000000000000000000000003229 111.0
PYH3_k127_1048998_24 LTXXQ motif family protein - - - 0.000000000000000000003969 98.0
PYH3_k127_1048998_3 Periplasmic binding protein K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 489.0
PYH3_k127_1048998_4 ABC-type transport system involved in resistance to organic solvents, permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006499 422.0
PYH3_k127_1048998_5 L-phenylalanine transmembrane transporter activity K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007295 400.0
PYH3_k127_1048998_6 Acetyl-CoA hydrolase/transferase N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007136 381.0
PYH3_k127_1048998_7 Abc transporter K02065 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004718 368.0
PYH3_k127_1048998_8 ABC transporter K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 312.0
PYH3_k127_1048998_9 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002127 309.0
PYH3_k127_1101358_0 Carboxylesterase K06999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008701 284.0
PYH3_k127_1101358_1 Protein of unknown function (DUF2889) - - - 0.0000000000000000000000000000000000000000000000000000000000004342 218.0
PYH3_k127_1101358_2 PFAM Restriction endonuclease K07448 - - 0.000000000000003936 86.0
PYH3_k127_1112864_0 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001774 584.0
PYH3_k127_1112864_1 Fad dependent oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000638 468.0
PYH3_k127_1112864_2 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001984 337.0
PYH3_k127_1112864_3 transport system small permease component - - - 0.0000000000000000000000000000000000000000000000000000002064 199.0
PYH3_k127_1120564_0 Amidase K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003072 575.0
PYH3_k127_1120564_1 PFAM extracellular solute-binding protein family 1 K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 565.0
PYH3_k127_1120564_2 Bacterial extracellular solute-binding protein K05813 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 462.0
PYH3_k127_1120564_3 Part of the ABC transporter complex UgpABCE involved in sn-glycerol-3-phosphate import. Responsible for energy coupling to the transport system K05816,K10111,K10112 - 3.6.3.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002759 440.0
PYH3_k127_1120564_4 transporter permease K05814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001187 422.0
PYH3_k127_1120564_5 probably responsible for the translocation of the substrate across the membrane K02026,K05815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 407.0
PYH3_k127_1120564_6 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000002656 228.0
PYH3_k127_1120564_7 Glycerophosphoryl diester phosphodiesterase K01126 - 3.1.4.46 0.0000000001567 71.0
PYH3_k127_1154319_0 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003297 565.0
PYH3_k127_1154319_1 mechanosensitive K05802 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000366 393.0
PYH3_k127_1154319_2 Integral membrane protein TerC family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002436 349.0
PYH3_k127_1154319_3 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0031974,GO:0031981,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0046483,GO:0070013,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:1901360 2.1.1.176 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 343.0
PYH3_k127_1154319_4 RadC-like JAB domain K03630 - - 0.0000000000000000000000000000000000000000000000000000000000002124 215.0
PYH3_k127_1154319_5 - - - - 0.0000000000000000000000000000000000000000004733 168.0
PYH3_k127_1154319_6 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.000000000000000000000000000001105 122.0
PYH3_k127_1154319_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000001369 95.0
PYH3_k127_1158605_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 1.837e-299 929.0
PYH3_k127_1158605_1 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000003156 269.0
PYH3_k127_1158605_2 One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA K02834 - - 0.00000000000000000000000000000008463 129.0
PYH3_k127_1167945_0 A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003256 463.0
PYH3_k127_1167945_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006594 439.0
PYH3_k127_1167945_2 abc transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 348.0
PYH3_k127_1167945_3 Short-chain dehydrogenase reductase sdr K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003138 324.0
PYH3_k127_1167945_4 dioxygenase K15777 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000008014 294.0
PYH3_k127_1167945_5 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000001044 235.0
PYH3_k127_1167945_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000005937 222.0
PYH3_k127_1168670_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving both as a receptor for the preprotein-SecB complex and as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 - - 0.0 1283.0
PYH3_k127_1168670_1 COG2804 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02652 - - 3.321e-240 755.0
PYH3_k127_1168670_10 Cytochrome c assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000007003 226.0
PYH3_k127_1168670_11 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000002547 86.0
PYH3_k127_1168670_2 type II secretion system protein K02653 - - 2.101e-197 622.0
PYH3_k127_1168670_3 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003757 504.0
PYH3_k127_1168670_4 Domain of unknown function DUF21 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000869 455.0
PYH3_k127_1168670_5 Type IV leader peptidase family K02654 - 3.4.23.43 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006219 370.0
PYH3_k127_1168670_6 SMART AAA ATPase K06923 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 364.0
PYH3_k127_1168670_7 Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity K18778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008005 356.0
PYH3_k127_1168670_8 Belongs to the Nudix hydrolase family K03574 - 3.6.1.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 320.0
PYH3_k127_1168670_9 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000006748 231.0
PYH3_k127_1194267_0 Thi4 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 541.0
PYH3_k127_1194267_1 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 340.0
PYH3_k127_1194267_10 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.0000000000000000000000000133 113.0
PYH3_k127_1194267_11 Phosphopantetheine attachment site K02078 - - 0.0000000000000000000000008018 111.0
PYH3_k127_1194267_12 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases - - - 0.0000000000000000003643 103.0
PYH3_k127_1194267_13 Belongs to the P-Pant transferase superfamily K06133 - - 0.0000003665 60.0
PYH3_k127_1194267_2 amp-dependent synthetase and ligase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003524 314.0
PYH3_k127_1194267_3 Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004776 312.0
PYH3_k127_1194267_4 Phosphate acyltransferases - - - 0.00000000000000000000000000000000000000000000000000000000001519 220.0
PYH3_k127_1194267_5 PFAM thioesterase superfamily protein K07107 - - 0.000000000000000000000000000000000000000000000000007922 188.0
PYH3_k127_1194267_6 Beta-ketoacyl synthase, N-terminal domain - - - 0.0000000000000000000000000000000000000000000001111 180.0
PYH3_k127_1194267_7 membrane - - - 0.000000000000000000000000000000000000000001893 162.0
PYH3_k127_1194267_8 MMPL family - - - 0.000000000000000000000000000000000000001316 157.0
PYH3_k127_1194267_9 Outer membrane lipoprotein carrier protein LolA - - - 0.000000000000000000000000000003667 132.0
PYH3_k127_1198040_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688 - - 0.0 1492.0
PYH3_k127_1198040_1 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000007312 188.0
PYH3_k127_1198040_2 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.00000000000000000000000000000000000004064 146.0
PYH3_k127_1198367_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 GO:0000096,GO:0003674,GO:0003824,GO:0004013,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006534,GO:0006555,GO:0006575,GO:0006725,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009069,GO:0009116,GO:0009119,GO:0009987,GO:0016787,GO:0016801,GO:0016802,GO:0017144,GO:0019752,GO:0033353,GO:0034641,GO:0042278,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046128,GO:0046439,GO:0046483,GO:0046498,GO:0046500,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:1901135,GO:1901360,GO:1901564,GO:1901605,GO:1901657 3.3.1.1 1.023e-255 796.0
PYH3_k127_1198367_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000298 602.0
PYH3_k127_1198367_10 CHASE2 K01768 - 4.6.1.1 0.000000000000000000000000000000000000000001185 164.0
PYH3_k127_1198367_2 Methylenetetrahydrofolate reductase K00297 GO:0000166,GO:0003674,GO:0003824,GO:0004489,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006575,GO:0006725,GO:0006730,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009396,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0018130,GO:0019438,GO:0019752,GO:0022607,GO:0034641,GO:0036094,GO:0042398,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0048037,GO:0050660,GO:0050662,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0071949,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.5.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002008 415.0
PYH3_k127_1198367_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006553,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0008837,GO:0009058,GO:0009066,GO:0009067,GO:0009085,GO:0009089,GO:0009987,GO:0016053,GO:0016853,GO:0016854,GO:0016855,GO:0019752,GO:0036361,GO:0043436,GO:0043648,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046451,GO:0047661,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003098 366.0
PYH3_k127_1198367_4 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000504 350.0
PYH3_k127_1198367_5 Phage integrase, N-terminal SAM-like domain K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004014 325.0
PYH3_k127_1198367_6 Lipid A Biosynthesis K02517,K12974 - 2.3.1.241,2.3.1.242 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003149 287.0
PYH3_k127_1198367_7 Protein of unknown function, DUF484 K09921 - - 0.00000000000000000000000000000000000000000000000000000000000000000004624 238.0
PYH3_k127_1198367_8 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K06969 - 2.1.1.191 0.000000000000000000000000000000000000000000000000000000007048 216.0
PYH3_k127_1198367_9 CoA binding domain - - - 0.000000000000000000000000000000000000000000001843 169.0
PYH3_k127_1205506_0 Acyl-CoA dehydrogenase, C-terminal domain K09456 - - 5.804e-196 621.0
PYH3_k127_1205506_1 PHB de-polymerase C-terminus K05973 - 3.1.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004568 564.0
PYH3_k127_1205506_2 peptidase S45, penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 473.0
PYH3_k127_1205506_3 Disulfide bond formation protein DsbB - - - 0.00000000000000000000000000000000000000000004137 170.0
PYH3_k127_1206334_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 6.078e-276 854.0
PYH3_k127_1206334_1 Class II Aldolase and Adducin N-terminal domain - - - 2.029e-271 852.0
PYH3_k127_1206334_10 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.00000000000000000000000000000000000000000000000000000000000000006597 231.0
PYH3_k127_1206334_11 L,D-transpeptidase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000002936 233.0
PYH3_k127_1206334_12 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000002233 220.0
PYH3_k127_1206334_13 Belongs to the GcvT family K06980 - - 0.000000000000000000000000000000000000000000000000000000003739 209.0
PYH3_k127_1206334_14 dna polymerase iii K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000002581 209.0
PYH3_k127_1206334_15 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000000000000000000000000000000168 197.0
PYH3_k127_1206334_16 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 GO:0002097,GO:0002100,GO:0003674,GO:0003824,GO:0004000,GO:0005488,GO:0006139,GO:0006382,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008251,GO:0008270,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016553,GO:0016787,GO:0016810,GO:0016814,GO:0019239,GO:0034470,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0052717,GO:0071704,GO:0090304,GO:1901360 3.5.4.33 0.000000000000000000000000000000000000000000001596 168.0
PYH3_k127_1206334_17 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000000000000004611 168.0
PYH3_k127_1206334_18 Sh3 type 3 domain protein - - - 0.000000000000000000000000000785 121.0
PYH3_k127_1206334_19 Tetratricopeptide repeat - - - 0.00000000000000000005683 93.0
PYH3_k127_1206334_2 arylsulfatase A K01130 - 3.1.6.1 1.242e-270 840.0
PYH3_k127_1206334_20 Domain of unknown function (DUF4124) - - - 0.00000000000002824 85.0
PYH3_k127_1206334_21 - - - - 0.00001922 55.0
PYH3_k127_1206334_22 Domain of unknown function (DUF4936) - - - 0.000202 55.0
PYH3_k127_1206334_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 1.619e-237 742.0
PYH3_k127_1206334_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008006 485.0
PYH3_k127_1206334_5 polysaccharide biosynthetic process K00721 - 2.4.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003559 419.0
PYH3_k127_1206334_6 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 - 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007441 395.0
PYH3_k127_1206334_7 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000682 385.0
PYH3_k127_1206334_8 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008988 282.0
PYH3_k127_1206334_9 PAP2 superfamily K19803 - 2.7.4.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003049 303.0
PYH3_k127_1249718_0 Glycosyltransferase family 28 C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 576.0
PYH3_k127_1249718_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 407.0
PYH3_k127_1249718_2 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005543 329.0
PYH3_k127_1249718_3 Belongs to the TrpC family K01609 - 4.1.1.48 0.00000000000000000000000000000000000000000000000000000000000000000000102 239.0
PYH3_k127_1249718_4 Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol K06134 - - 0.000000000000000000000000000000000000000000000000000000000000000000009023 240.0
PYH3_k127_1249718_5 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) - - - 0.00000000000001057 82.0
PYH3_k127_1249718_6 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.0000000006107 72.0
PYH3_k127_1258083_0 D,D-heptose 1,7-bisphosphate phosphatase K03273 - 3.1.3.82,3.1.3.83 0.0000000000000000000000000000000000000000000000000000000000000000000000001223 264.0
PYH3_k127_1258083_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000001377 245.0
PYH3_k127_1258083_2 PFAM Phospholipid glycerol acyltransferase K00655 - 2.3.1.51 0.000000000000000000000000000000000000000000000000000000000003711 221.0
PYH3_k127_1258796_0 Sulfatase - - - 1.19e-219 689.0
PYH3_k127_1258796_1 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 1.352e-215 680.0
PYH3_k127_1258796_2 Domain of Unknown Function (DUF748) - - - 3.832e-205 672.0
PYH3_k127_1261238_0 Catalyzes the isomerization of citrate to isocitrate via cis-aconitate K01681 - 4.2.1.3 0.0 1384.0
PYH3_k127_1261238_1 2-methylcitrate dehydratase K01720 - 4.2.1.79 7.354e-254 788.0
PYH3_k127_1261238_2 Thioredoxin-like - - - 0.000000000000000000000000000155 129.0
PYH3_k127_1269289_0 Redoxin K03386 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000000000000000002297 236.0
PYH3_k127_1269289_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000009219 211.0
PYH3_k127_1269289_2 OsmC-like protein K04063 - - 0.00000000000000000000000000000000000000000000000123 177.0
PYH3_k127_1269289_3 branched-chain amino acid permease (azaleucine resistance) - - - 0.00000000000000000000000000000000000000000001518 170.0
PYH3_k127_126991_0 General secretory system II protein E domain protein K02454,K02652,K12276 - - 0.0 1144.0
PYH3_k127_126991_1 CHASE2 K01768 - 4.6.1.1 4.237e-270 850.0
PYH3_k127_126991_2 metal-dependent phosphohydrolase HD sub domain - - - 1.824e-238 749.0
PYH3_k127_126991_3 TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007042 449.0
PYH3_k127_126991_4 SMART beta-lactamase domain protein K01120 - 3.1.4.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 363.0
PYH3_k127_126991_5 (FHA) domain - - - 0.00000000000000000000000000000000000403 139.0
PYH3_k127_126991_6 Belongs to the N-Me-Phe pilin family K02650 - - 0.00000000000000003761 81.0
PYH3_k127_126991_7 - - - - 0.00000002117 61.0
PYH3_k127_1279094_0 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000394 325.0
PYH3_k127_1279094_1 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000005007 178.0
PYH3_k127_1279094_2 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 - 2.5.1.78 0.0000000000000000000000000000000000000043 153.0
PYH3_k127_1279094_3 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.000000000000000000000000000000000001428 150.0
PYH3_k127_1289328_0 ABC-type multidrug transport system, ATPase and permease K06147 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 345.0
PYH3_k127_1289328_1 SMART PAS domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003471 284.0
PYH3_k127_1289328_2 PFAM histone deacetylase superfamily K04768 - - 0.0000000006455 60.0
PYH3_k127_1293931_0 RmuC family K09760 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008658 458.0
PYH3_k127_1293931_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 349.0
PYH3_k127_1295310_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K05807 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000254 368.0
PYH3_k127_1295310_1 Nad-dependent epimerase dehydratase K22025 - 1.1.1.410 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005703 293.0
PYH3_k127_1295310_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000007921 57.0
PYH3_k127_1323101_0 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001141 341.0
PYH3_k127_1323101_1 AMP-binding enzyme K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000153 326.0
PYH3_k127_1330862_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.302e-195 617.0
PYH3_k127_1330862_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001833 558.0
PYH3_k127_1330862_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000444 153.0
PYH3_k127_1330862_3 Preprotein translocase, YajC subunit K03210 - - 0.000000000000000000000000000000005745 138.0
PYH3_k127_1346331_0 Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family K00383 - 1.8.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003522 536.0
PYH3_k127_1346331_1 cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 484.0
PYH3_k127_1346331_2 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000004366 221.0
PYH3_k127_1346331_3 Sulfite exporter TauE/SafE K07090 - - 0.000000000000001277 81.0
PYH3_k127_1357965_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.082e-318 983.0
PYH3_k127_1357965_1 Pyruvate flavodoxin ferredoxin oxidoreductase domain protein K00174 - 1.2.7.11,1.2.7.3 2.071e-310 983.0
PYH3_k127_1357965_10 'Cold-shock' DNA-binding domain K03704 - - 0.0000000000000000000000000000000239 126.0
PYH3_k127_1357965_2 amino acid K11959 - - 1.539e-231 722.0
PYH3_k127_1357965_3 PFAM Thiamine pyrophosphate K00175 - 1.2.7.11,1.2.7.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 602.0
PYH3_k127_1357965_4 aminotransferase class I and II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 496.0
PYH3_k127_1357965_5 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 GO:0003674,GO:0003824,GO:0004801,GO:0016740,GO:0016744 2.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003318 435.0
PYH3_k127_1357965_6 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007606 342.0
PYH3_k127_1357965_7 Metal dependent phosphohydrolases with conserved 'HD' motif. K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 323.0
PYH3_k127_1357965_8 decarboxylase K01607 - 4.1.1.44 0.000000000000000000000000000000000000000000000000000000000000002464 224.0
PYH3_k127_1357965_9 Domain of unknown function (DUF4337) - - - 0.000000000000000000000000000000000000000000000000000005799 195.0
PYH3_k127_1365577_0 Major facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 377.0
PYH3_k127_1365577_1 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 374.0
PYH3_k127_1366029_0 PERMEase K06901 - - 7.485e-222 709.0
PYH3_k127_1366029_1 Acyl-CoA dehydrogenase, C-terminal domain - - - 2.505e-205 653.0
PYH3_k127_1366029_10 Major facilitator superfamily MFS_1 K02445 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 398.0
PYH3_k127_1366029_11 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001196 373.0
PYH3_k127_1366029_12 Isochorismatase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004655 336.0
PYH3_k127_1366029_13 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008435 328.0
PYH3_k127_1366029_14 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004865 327.0
PYH3_k127_1366029_15 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007903 285.0
PYH3_k127_1366029_16 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005087 289.0
PYH3_k127_1366029_17 enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000001494 189.0
PYH3_k127_1366029_2 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 7.434e-205 651.0
PYH3_k127_1366029_3 Extracellular ligand-binding receptor K01999 - - 3.815e-194 613.0
PYH3_k127_1366029_4 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009664 568.0
PYH3_k127_1366029_5 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001888 550.0
PYH3_k127_1366029_6 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001453 495.0
PYH3_k127_1366029_7 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009135 444.0
PYH3_k127_1366029_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006264 387.0
PYH3_k127_1366029_9 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 383.0
PYH3_k127_1378466_0 PFAM L-carnitine dehydratase bile acid-inducible protein F K01796 - 5.1.99.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 486.0
PYH3_k127_1378466_1 Alkyl sulfatase dimerisation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004794 262.0
PYH3_k127_1378466_2 PFAM Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000001269 201.0
PYH3_k127_1386645_0 Hydantoinase B/oxoprolinase K01469 - 3.5.2.9 5.482e-236 739.0
PYH3_k127_1386645_1 of the major facilitator superfamily K07552 - - 0.0000000000000002557 82.0
PYH3_k127_1397051_0 Outer Membrane Lipoprotein K03098 - - 0.000000000000000000000000000000000000000000000000000000000000000001679 241.0
PYH3_k127_1397051_1 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000009311 188.0
PYH3_k127_1397051_2 3-oxo-5-alpha-steroid 4-dehydrogenase - - - 0.0000000000000000000000000000000000000000000002192 168.0
PYH3_k127_1399517_0 EVE domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000004691 231.0
PYH3_k127_1399517_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000001474 189.0
PYH3_k127_1399517_2 ABC-type Fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000001877 191.0
PYH3_k127_1399517_3 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.0000000000000000000000000000008343 124.0
PYH3_k127_1420503_0 Bacterial extracellular solute-binding protein K05772 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000565 409.0
PYH3_k127_1420503_1 Binding-protein-dependent transport system inner membrane component K05773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001068 281.0
PYH3_k127_1420503_2 ABC transporter K06857 - 3.6.3.55 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007819 283.0
PYH3_k127_1420503_3 Sulfite exporter TauE/SafE K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000003109 228.0
PYH3_k127_1420503_4 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.00000000000000000000000000000000000000000000000000000000003495 222.0
PYH3_k127_1420503_5 MoeA domain protein domain I and II K03750 - 2.10.1.1 0.0000000000000000000008412 108.0
PYH3_k127_1431579_0 radical SAM domain protein K04070 - 1.97.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001129 433.0
PYH3_k127_1431579_1 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.00000000000000000000000000000000000000000000000000000000000000000001835 236.0
PYH3_k127_1431579_2 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000002996 127.0
PYH3_k127_1431845_0 reductase, alpha subunit K00394 - 1.8.99.2 0.0 1072.0
PYH3_k127_1431845_1 PUA-like domain K00958 - 2.7.7.4 3.054e-205 642.0
PYH3_k127_1431845_2 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004317 436.0
PYH3_k127_1431845_3 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004112 269.0
PYH3_k127_1431845_4 lipid catabolic process - - - 0.00000000000000000000000000000000001919 152.0
PYH3_k127_1431845_5 Pfam Family of - - - 0.000000000000000000000000000000598 141.0
PYH3_k127_1431845_6 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.0000000000000000000003234 96.0
PYH3_k127_1431845_7 RNA recognition motif - - - 0.0002229 48.0
PYH3_k127_1453105_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002247 605.0
PYH3_k127_1453105_1 Amidohydrolase family K06015 - 3.5.1.81 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006793 274.0
PYH3_k127_1453105_2 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000001632 83.0
PYH3_k127_1486146_0 Mannose-6-phosphate isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 563.0
PYH3_k127_1486146_1 Glycosyl transferase group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007326 341.0
PYH3_k127_1486146_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001137 300.0
PYH3_k127_1486146_3 Glycosyltransferase like family 2 K13002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001023 279.0
PYH3_k127_1486146_4 Methyltransferase FkbM domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000189 243.0
PYH3_k127_1486146_5 ADP-glyceromanno-heptose 6-epimerase activity K19997,K22320 - 1.1.1.412,5.1.3.26 0.000000000000000000000000000000000000000000000000000000000000000005038 240.0
PYH3_k127_1486146_7 methyltransferase activity K00563,K13307,K13330,K15256 - 2.1.1.187,2.1.1.235,2.1.1.324 0.000000000000000000000000000000000000000000000000000001108 198.0
PYH3_k127_150612_0 Acyl-CoA synthetase (NDP forming) K09181 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009531 494.0
PYH3_k127_1517385_0 COG1593 TRAP-type C4-dicarboxylate transport system, large permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009794 526.0
PYH3_k127_1517385_1 COG1638 TRAP-type C4-dicarboxylate transport system, periplasmic component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004978 342.0
PYH3_k127_1517385_2 UDP-glucose 4-epimerase K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000006319 251.0
PYH3_k127_1517385_3 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000005343 105.0
PYH3_k127_1544953_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007007 443.0
PYH3_k127_1544953_1 Molybdopterin converting factor, large subunit K03635 - 2.8.1.12 0.000000000000000000000000000000000000000000000000000000003974 204.0
PYH3_k127_1544953_2 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 - - 0.00000000000000000000000000000000003308 144.0
PYH3_k127_1549108_0 PFAM Peptidase M48 K06013 - 3.4.24.84 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 497.0
PYH3_k127_1549108_1 mechanosensitive ion channel K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 385.0
PYH3_k127_1549108_2 3'-to-5' exoribonuclease specific for small oligoribonucleotides K13288 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001539 263.0
PYH3_k127_1549108_3 diol metabolic process K01724 - 4.2.1.96 0.0000000000000000000000000000000000000000008525 171.0
PYH3_k127_1549108_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.000000000000000000000000000000000006296 138.0
PYH3_k127_1549108_5 Putative prokaryotic signal transducing protein - - - 0.00000000000000000001061 96.0
PYH3_k127_1579815_0 Beta-Casp domain K07576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 473.0
PYH3_k127_1579815_2 Cytochrome c - - - 0.00000000279 61.0
PYH3_k127_1579815_3 FixH family K09926 - - 0.000008774 49.0
PYH3_k127_1582700_0 Prolyl oligopeptidase family - - - 5.8e-245 776.0
PYH3_k127_1582700_1 Zn_pept - - - 1.005e-228 721.0
PYH3_k127_1582700_10 PFAM Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000000000000000004796 194.0
PYH3_k127_1582700_11 TonB dependent biopolymer transporter integral cytoplasmic membrane subunit, working with ExbB K03559 - - 0.00000000000000000000000000000000000000000000000000003922 193.0
PYH3_k127_1582700_12 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.000000000000000000000000000000000000000000000000000121 192.0
PYH3_k127_1582700_13 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.0000000000000000000000000000000000000000007277 173.0
PYH3_k127_1582700_14 Conserved protein containing a Zn-ribbon-like motif possibly RNA-binding - - - 0.00000000000000000000000000000004067 134.0
PYH3_k127_1582700_16 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000008568 97.0
PYH3_k127_1582700_2 TonB dependent receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009439 617.0
PYH3_k127_1582700_3 Ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001666 379.0
PYH3_k127_1582700_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007407 299.0
PYH3_k127_1582700_5 MotA/TolQ/ExbB proton channel family K03561 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007495 295.0
PYH3_k127_1582700_6 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001469 263.0
PYH3_k127_1582700_7 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000049 246.0
PYH3_k127_1582700_8 ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000001022 241.0
PYH3_k127_1582700_9 Belongs to the binding-protein-dependent transport system permease family - - - 0.000000000000000000000000000000000000000000000000000000000004738 218.0
PYH3_k127_1598374_0 D-galactarate dehydratase / Altronate hydrolase, C terminus K16846,K16850 - 4.2.1.7,4.4.1.24 4.909e-214 674.0
PYH3_k127_1598374_1 PhoD-like phosphatase, N-terminal domain K01113 - 3.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 529.0
PYH3_k127_1598374_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
PYH3_k127_1598374_3 SAF K16845 - 4.4.1.24 0.00000000000000000000000000000000000000001447 154.0
PYH3_k127_1598374_4 Chalcone isomerase-like - - - 0.0000000000000000000001259 102.0
PYH3_k127_1598987_0 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 - 3.1.3.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 475.0
PYH3_k127_1598987_1 major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000000000009924 201.0
PYH3_k127_1598987_2 SWI complex, BAF60b domains - - - 0.0000000000000000000000000000000001542 134.0
PYH3_k127_1598987_3 Beta-lactamase K01069 - 3.1.2.6 0.00000001269 56.0
PYH3_k127_1614762_0 Glucose sorbosone K21430 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 481.0
PYH3_k127_1614762_1 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 389.0
PYH3_k127_1614762_2 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003568 377.0
PYH3_k127_1614762_3 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000003816 258.0
PYH3_k127_1614762_4 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000008681 228.0
PYH3_k127_1614762_5 Outer membrane protein beta-barrel domain - - - 0.00000000000005083 83.0
PYH3_k127_1614762_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000004445 66.0
PYH3_k127_1614959_0 Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B K02274 - 1.9.3.1 4.019e-289 893.0
PYH3_k127_1614959_1 Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) K02275 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001621 494.0
PYH3_k127_1614959_2 COG1845 Heme copper-type cytochrome quinol oxidase, subunit 3 K02276 - 1.9.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 376.0
PYH3_k127_1614959_3 oxidase assembly K02258 - - 0.0000000000000000000000000000000000000000000000000000000000000000000008407 242.0
PYH3_k127_1614959_4 Protein of unknown function (DUF2909) - - - 0.0000000000006961 72.0
PYH3_k127_1614959_5 Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway K02169 - 2.1.1.197 0.0000000002189 62.0
PYH3_k127_1614959_6 Protein of unknown function (DUF2970) - - - 0.0008198 50.0
PYH3_k127_1627054_0 acyl-CoA dehydrogenase K06445 - - 6.768e-317 1002.0
PYH3_k127_1627054_1 ABC transporter transmembrane region K06147 - - 6.999e-237 746.0
PYH3_k127_1627054_2 Belongs to the thiolase family K00626 - 2.3.1.9 7.399e-202 635.0
PYH3_k127_1627054_3 3-hydroxyacyl-CoA dehydrogenase K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006815 388.0
PYH3_k127_1627054_4 Belongs to the peptidase S11 family K07262 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002023 299.0
PYH3_k127_1627054_5 Histidine-specific methyltransferase, SAM-dependent - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001845 278.0
PYH3_k127_1627054_6 Bacterial regulatory proteins, tetR family - - - 0.00000000000000000000000000000000000000000000000000000000000003282 222.0
PYH3_k127_1650717_0 Peptidogalycan biosysnthesis/recognition K09919 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004423 433.0
PYH3_k127_1650717_1 PFAM Short-chain dehydrogenase reductase SDR K00059 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0010130,GO:0016043,GO:0016491,GO:0016614,GO:0016616,GO:0018913,GO:0018915,GO:0022607,GO:0042537,GO:0043933,GO:0044085,GO:0044237,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:1901360 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008878 343.0
PYH3_k127_1650717_2 Belongs to the P(II) protein family K04751 - - 0.00000000000000000000000000000000000000000000000000000000287 201.0
PYH3_k127_1650717_3 PFAM glycerophosphoryl diester phosphodiesterase K01126 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0008081,GO:0008889,GO:0016787,GO:0016788,GO:0042578,GO:0043167,GO:0043169,GO:0046872,GO:0047389,GO:0047395 3.1.4.46 0.0000000000000000000000000000000000000000003745 161.0
PYH3_k127_1650717_4 Small MutS-related domain - - - 0.00000000000000000000000000000002641 127.0
PYH3_k127_1651653_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 7.008e-254 791.0
PYH3_k127_1669709_0 alpha/beta hydrolase fold K03821 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008655 358.0
PYH3_k127_1669709_1 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000599 232.0
PYH3_k127_1669709_2 Phage plasmid primase P4 family K06919 - - 0.00000000000000000000000000000000000000000000001498 175.0
PYH3_k127_1669709_3 PFAM DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000001312 164.0
PYH3_k127_1694293_0 - - - - 0.00000000000000000000000000000000000000000000000009175 195.0
PYH3_k127_1694293_1 - - - - 0.00001962 50.0
PYH3_k127_1698840_0 acyl-CoA dehydrogenase K11731 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003492 593.0
PYH3_k127_1698840_1 Acetyl propionyl-CoA carboxylase, alpha subunit K01968,K13777 - 6.4.1.4,6.4.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002477 425.0
PYH3_k127_1704878_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 391.0
PYH3_k127_1704878_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K01652,K12673 - 2.2.1.6,2.5.1.66 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003848 368.0
PYH3_k127_1712899_0 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.00000000000000000000000000000000000000000000000000000000000000000003538 248.0
PYH3_k127_1712899_1 FtsX-like permease family K02004 - - 0.000000000000000003367 87.0
PYH3_k127_1712899_2 Amidohydrolase family - - - 0.000000009691 56.0
PYH3_k127_1716210_0 benzoyl-CoA oxygenase K15512 - 1.14.13.208 4.781e-266 827.0
PYH3_k127_1716210_1 enoyl-CoA hydratase K15513 - 4.1.2.44 1.607e-247 788.0
PYH3_k127_1716210_10 cytochrome - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005203 325.0
PYH3_k127_1716210_11 4-carboxy-4-hydroxy-2-oxoadipate aldolase oxaloacetate decarboxylase K10218 - 4.1.3.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 303.0
PYH3_k127_1716210_12 4,5-dihydroxyphthalate decarboxylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001947 277.0
PYH3_k127_1716210_13 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001107 258.0
PYH3_k127_1716210_14 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003594 275.0
PYH3_k127_1716210_15 denitrification pathway - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001652 257.0
PYH3_k127_1716210_16 Domain of unknown function (DUF1932) - - - 0.000000000000000000000000000000000000000000000000000000000000000002254 237.0
PYH3_k127_1716210_17 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K15546 - - 0.00000000000000000000000000000000000000000000000000000000000000005831 231.0
PYH3_k127_1716210_18 metal-dependent hydrolase of the TIM-barrel fold - - - 0.000000000000000000000000000000000000000000000000000000000004325 231.0
PYH3_k127_1716210_19 response regulator - - - 0.00000000000000000000000000000000000000000000000000003461 198.0
PYH3_k127_1716210_2 AMP-binding enzyme C-terminal domain K04110 - 6.2.1.25 2.841e-226 711.0
PYH3_k127_1716210_20 Flavodoxin - - - 0.000000000000000000000000000000000000000000000000005922 185.0
PYH3_k127_1716210_21 Pfam Response regulator receiver - - - 0.00000000000000000000000000000000000000000003178 167.0
PYH3_k127_1716210_3 response regulator K02481 - - 2.511e-214 679.0
PYH3_k127_1716210_4 Histidine kinase K02482 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 584.0
PYH3_k127_1716210_5 benzoyl-CoA oxygenase K15512 - 1.14.13.208 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 568.0
PYH3_k127_1716210_6 Amidohydrolase K03392,K10220 - 4.1.1.45,4.2.1.83 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001185 527.0
PYH3_k127_1716210_7 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004565 379.0
PYH3_k127_1716210_8 Fumarylacetoacetate (FAA) hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 357.0
PYH3_k127_1716210_9 D-isomer specific 2-hydroxyacid dehydrogenase K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 328.0
PYH3_k127_1734391_0 Belongs to the IlvD Edd family K01687,K22186 - 4.2.1.82,4.2.1.9 5.823e-276 859.0
PYH3_k127_1734391_1 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003302 300.0
PYH3_k127_1734391_2 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002405 293.0
PYH3_k127_1734391_3 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001455 285.0
PYH3_k127_1734391_4 PFAM fatty acid desaturase K00496 - 1.14.15.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001093 290.0
PYH3_k127_1734391_5 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K15919,K18606 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0009853,GO:0009854,GO:0009987,GO:0016491,GO:0016614,GO:0016616,GO:0016618,GO:0030267,GO:0043094,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.1.1.237 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002374 302.0
PYH3_k127_1734391_6 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.00000000000000000000000000000000000000000000000000002436 207.0
PYH3_k127_1785769_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 1.336e-195 620.0
PYH3_k127_1785769_1 TIGRFAM Ubiquinone biosynthesis hydroxylase, UbiH UbiF VisC COQ6 family K03185 - - 0.00000000000000000000000000000000005787 140.0
PYH3_k127_1785769_2 - - - - 0.0000000000008216 73.0
PYH3_k127_1785769_3 phosphate starvation-inducible protein PhoH K06217 - - 0.00000000001734 65.0
PYH3_k127_1839996_0 Bacterial extracellular solute-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000591 428.0
PYH3_k127_1839996_1 NADH ubiquinone oxidoreductase 20 kDa subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002175 275.0
PYH3_k127_1839996_2 Respiratory-chain NADH dehydrogenase, 49 Kd subunit - - - 0.0000000000000000000000000000000000000000000000000000000005091 204.0
PYH3_k127_1839996_3 Acylphosphatase K01512 - 3.6.1.7 0.000000000000001296 87.0
PYH3_k127_1866448_0 Belongs to the anaerobic coproporphyrinogen-III oxidase family - - - 6.272e-199 629.0
PYH3_k127_1866448_1 PFAM ATP-binding region, ATPase domain protein K02486 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 308.0
PYH3_k127_1866448_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.000000000654 62.0
PYH3_k127_1867205_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K08483 - 2.7.3.9 4.576e-214 683.0
PYH3_k127_1867205_1 Transfers a succinyl group from succinyl-CoA to L- homoserine, forming succinyl-L-homoserine K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001598 573.0
PYH3_k127_1867205_2 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 511.0
PYH3_k127_1867205_3 TIGRFAM methionine biosynthesis protein MetW - - - 0.000000000000000000000000000000000000000000000000000000000000000000002728 256.0
PYH3_k127_1867205_4 Phosphotransferase System K11189 - - 0.000000000000000000000000000000004933 129.0
PYH3_k127_1867205_5 AI-2E family transporter - - - 0.000000000000000000000001013 115.0
PYH3_k127_1867205_6 PFAM PTS system fructose subfamily IIA component K02821 - 2.7.1.194 0.000000001582 59.0
PYH3_k127_1872528_0 Malic enzyme K00029 - 1.1.1.40 0.0 1056.0
PYH3_k127_1872528_1 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 461.0
PYH3_k127_1872528_2 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006831 437.0
PYH3_k127_1872528_3 esterase of the alpha-beta hydrolase superfamily K07001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 425.0
PYH3_k127_1872528_4 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002843 400.0
PYH3_k127_1872528_5 NUDIX domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001315 233.0
PYH3_k127_1872528_6 - - - - 0.00000000000000000003166 92.0
PYH3_k127_1872528_7 - - - - 0.0000000000000001313 81.0
PYH3_k127_1872528_8 SapC - - - 0.0002231 46.0
PYH3_k127_1872939_0 PFAM major facilitator superfamily MFS_1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000109 449.0
PYH3_k127_1872939_1 COG0179 2-keto-4-pentenoate hydratase 2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) K16165 - 3.7.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001545 280.0
PYH3_k127_1872939_2 AMP-binding enzyme C-terminal domain K04110,K20458 - 6.2.1.25,6.2.1.27,6.2.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000004315 268.0
PYH3_k127_1872939_3 maleylacetoacetate isomerase K01801 - 5.2.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000005817 262.0
PYH3_k127_1872939_4 Catalytic LigB subunit of aromatic ring-opening dioxygenase K00455 - 1.13.11.15 0.0000000000000000000000000000000000000000000000001165 190.0
PYH3_k127_1872939_5 -Thioesterase K01075 - 3.1.2.23 0.000000000000000000004889 98.0
PYH3_k127_1888223_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 GO:0000166,GO:0000988,GO:0000989,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008144,GO:0008150,GO:0008270,GO:0009266,GO:0009408,GO:0009628,GO:0009889,GO:0009987,GO:0010033,GO:0010556,GO:0016043,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0016989,GO:0017076,GO:0017111,GO:0019219,GO:0019222,GO:0022607,GO:0030554,GO:0031323,GO:0031326,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033554,GO:0034620,GO:0035639,GO:0035966,GO:0035967,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0043169,GO:0043531,GO:0043933,GO:0044085,GO:0044183,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0051171,GO:0051252,GO:0051716,GO:0060255,GO:0061077,GO:0065003,GO:0065007,GO:0070887,GO:0071310,GO:0071840,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1903506,GO:2001141 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006901 463.0
PYH3_k127_1888223_1 peptidylprolyl isomerase K03769 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000001941 261.0
PYH3_k127_1888223_2 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000001649 244.0
PYH3_k127_1888223_3 ubiE/COQ5 methyltransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000008253 225.0
PYH3_k127_1888223_4 - - - - 0.000000000000000000000000000000000000000000000000000000005516 216.0
PYH3_k127_1888223_5 Ferredoxin, 2Fe-2S type, ISC system K04755 - - 0.0000000000000000000000000000000000000000000000004005 177.0
PYH3_k127_1888223_6 phosphatase homologous to the C-terminal domain of histone macroH2A1 K07478 - - 0.0000000000000000000000000000000253 134.0
PYH3_k127_1888223_7 FeS assembly protein IscX - - - 0.0000000000000000000005252 111.0
PYH3_k127_1888223_8 Belongs to the BolA IbaG family K05527 - - 0.0000000000002196 71.0
PYH3_k127_1888223_9 - - - - 0.000007208 58.0
PYH3_k127_1899936_0 Cytochrome c K02198 - - 1.328e-276 863.0
PYH3_k127_1899936_1 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02195 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002941 392.0
PYH3_k127_1899936_2 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02194 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004877 261.0
PYH3_k127_1899936_3 Redoxin K02199 - - 0.0000000000000000000000000000000000000000000000000000000000000007666 248.0
PYH3_k127_1899936_4 Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH K02197 - - 0.00000000000000000000000000000000000000000000000000000000000003409 219.0
PYH3_k127_1899936_5 subunit of a heme lyase K02200 - - 0.000000000000000000000000000000001885 141.0
PYH3_k127_1899936_6 Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes K02196 - - 0.000001744 59.0
PYH3_k127_1905896_0 PFAM AMP-dependent synthetase and ligase K00666 - - 1.412e-272 869.0
PYH3_k127_1905896_1 Mechanosensitive ion channel - - - 0.00007886 55.0
PYH3_k127_1944644_0 Na+ dependent nucleoside transporter N-terminus K03317 GO:0003674,GO:0005215,GO:0005337,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008150,GO:0015858,GO:0015931,GO:0015932,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071944,GO:1901264,GO:1901505,GO:1901642 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 472.0
PYH3_k127_1944644_1 Belongs to the 'phage' integrase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003106 413.0
PYH3_k127_1944644_2 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 291.0
PYH3_k127_1944644_3 ORF6N domain - - - 0.00000000000000000000000000000000000000000000000000000009917 199.0
PYH3_k127_1944644_4 UPF0761 membrane protein K07058 - - 0.0000000003885 64.0
PYH3_k127_1954089_0 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002953 379.0
PYH3_k127_1954089_1 Branched-chain amino acid transport system / permease component K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 352.0
PYH3_k127_1954089_2 ATPases associated with a variety of cellular activities K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007723 324.0
PYH3_k127_1954089_3 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 314.0
PYH3_k127_1954089_4 Hsp33 protein K04083 - - 0.000000000000000000000000000000000000000000000000000000000000000000000006398 252.0
PYH3_k127_1954089_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000007819 62.0
PYH3_k127_2016833_0 4-hydroxyphenylacetate 3-hydroxylase C terminal - - - 5.24e-256 796.0
PYH3_k127_2016833_1 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 7.318e-222 702.0
PYH3_k127_2016833_10 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000004144 181.0
PYH3_k127_2016833_2 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006932 563.0
PYH3_k127_2016833_3 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000948 470.0
PYH3_k127_2016833_4 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 375.0
PYH3_k127_2016833_5 PFAM Branched-chain amino acid transport system permease component K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000835 368.0
PYH3_k127_2016833_6 ROK family K00847 - 2.7.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003238 373.0
PYH3_k127_2016833_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 354.0
PYH3_k127_2016833_8 ABC transporter K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002608 328.0
PYH3_k127_2016833_9 PFAM Branched-chain amino acid transport system permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002873 317.0
PYH3_k127_2022781_0 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000004334 269.0
PYH3_k127_2022781_1 ATPase histidine kinase DNA gyrase B HSP90 domain protein K02668 - 2.7.13.3 0.0000000000000000000000000000000000000000514 164.0
PYH3_k127_2022781_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000002367 147.0
PYH3_k127_2022781_3 - K06950 - - 0.0000000001566 66.0
PYH3_k127_2022781_4 Protein of unknown function DUF99 K09120 - - 0.00004633 46.0
PYH3_k127_2051690_0 DNA helicase K03657 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003311 363.0
PYH3_k127_2051690_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000001318 241.0
PYH3_k127_2065621_0 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0 1045.0
PYH3_k127_2065621_1 impB/mucB/samB family K14161 - - 0.0000000000000000000000000000000000002723 146.0
PYH3_k127_2066110_0 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 459.0
PYH3_k127_2066110_1 Essential cell division protein that stabilizes the FtsZ protofilaments by cross-linking them and that serves as a cytoplasmic membrane anchor for the Z ring. Also required for the recruitment to the septal ring of downstream cell division proteins - - - 0.0000000001008 68.0
PYH3_k127_2067091_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 346.0
PYH3_k127_2067091_1 - - - - 0.000000000000000000000000000000000000000000000002173 184.0
PYH3_k127_2067091_2 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000003353 179.0
PYH3_k127_2067091_3 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2- polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) K03183 - 2.1.1.163,2.1.1.201 0.00000000000000000000001333 107.0
PYH3_k127_2067091_4 Phosphotransferase enzyme family K02204 - 2.7.1.39 0.00000000000001421 74.0
PYH3_k127_2070928_0 Psort location Cytoplasmic, score 7.50 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000184 551.0
PYH3_k127_2070928_1 Belongs to the ALAD family K01698 GO:0003674,GO:0003824,GO:0004655,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.2.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 498.0
PYH3_k127_2070928_2 NYN domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007193 401.0
PYH3_k127_2070928_3 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 285.0
PYH3_k127_2070928_4 transmembrane transcriptional regulator (Anti-sigma factor) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000109 259.0
PYH3_k127_2070928_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000008102 237.0
PYH3_k127_2070928_6 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000000000000000000006799 212.0
PYH3_k127_2070928_7 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.000000000000000000000000000000000000000000000000001378 188.0
PYH3_k127_2070928_8 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.00000000000000000000000000000000000000000000000001932 182.0
PYH3_k127_2070928_9 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.0000000000000000000000000000000000000000000001274 175.0
PYH3_k127_2091575_0 Catalyzes the ATP-dependent 2-thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32). The sulfur atoms are provided by the cysteine cysteine desulfurase (IscS) system K14058 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003262 405.0
PYH3_k127_2091575_1 Protein of unknown function (DUF3750) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 302.0
PYH3_k127_2091575_2 Enoyl-(Acyl carrier protein) reductase K03793 - 1.5.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000004555 273.0
PYH3_k127_2091575_3 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000001257 241.0
PYH3_k127_2091575_4 cyclopropane-fatty-acyl-phospholipid synthase K00574 - - - 0.00000000000000000000000000008307 117.0
PYH3_k127_2093099_0 Belongs to the GPAT DAPAT family K00631 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005883 600.0
PYH3_k127_2093099_1 Tartrate dehydrogenase K07246 - 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001085 539.0
PYH3_k127_2093099_2 Tartrate dehydrogenase K07246 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.83,1.1.1.93,4.1.1.73 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002076 497.0
PYH3_k127_2093099_3 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000003702 229.0
PYH3_k127_2093099_4 Porin subfamily - - - 0.0000000000000000000000000000000000004822 156.0
PYH3_k127_2093099_5 - - - - 0.0000000004147 68.0
PYH3_k127_2093099_6 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000004085 55.0
PYH3_k127_2115092_0 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005442 471.0
PYH3_k127_2115092_1 Chorismate mutase type II K01713,K14170 - 4.2.1.51,4.2.1.91,5.4.99.5 0.000000000000000000000000000000000002728 139.0
PYH3_k127_2142452_0 O-methyltransferase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004549 512.0
PYH3_k127_2142452_1 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008371 429.0
PYH3_k127_2142452_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 353.0
PYH3_k127_2162878_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 3.47e-291 908.0
PYH3_k127_2162878_1 Belongs to the Orn Lys Arg decarboxylase class-II family K01581 - 4.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 584.0
PYH3_k127_2162878_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007992 554.0
PYH3_k127_2162878_3 PFAM Serine threonine-protein kinase-like domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001217 349.0
PYH3_k127_2162878_4 dUTPase K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008753 352.0
PYH3_k127_2162878_5 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005148 293.0
PYH3_k127_2162878_6 adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002722 268.0
PYH3_k127_2162878_7 Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis K00287 - 1.5.1.3 0.0000000000000000000000000000000000000000000000000005508 190.0
PYH3_k127_2162878_8 Type IV pilus biogenesis stability protein PilW - - - 0.00000000000000000000000000006646 120.0
PYH3_k127_2175116_0 Methionine aminopeptidase K01265 GO:0003674,GO:0003824,GO:0004177,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008233,GO:0008235,GO:0008237,GO:0008238,GO:0009987,GO:0016787,GO:0019538,GO:0036211,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044424,GO:0044444,GO:0044464,GO:0046872,GO:0046914,GO:0070006,GO:0070011,GO:0070084,GO:0071704,GO:0140096,GO:1901564 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002528 434.0
PYH3_k127_2175116_1 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 393.0
PYH3_k127_2175116_2 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008444 377.0
PYH3_k127_2175116_3 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007422 349.0
PYH3_k127_2175116_4 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 329.0
PYH3_k127_2175116_5 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 293.0
PYH3_k127_2175116_6 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001381 269.0
PYH3_k127_2175116_7 Belongs to the CDS family K00981 GO:0003674,GO:0003824,GO:0004605,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006220,GO:0006221,GO:0006629,GO:0006644,GO:0006650,GO:0006655,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016020,GO:0016024,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044271,GO:0044281,GO:0044464,GO:0045017,GO:0046341,GO:0046471,GO:0046474,GO:0046483,GO:0046486,GO:0055086,GO:0070567,GO:0071704,GO:0071944,GO:0072527,GO:0072528,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.7.41 0.000137 53.0
PYH3_k127_2178086_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 3.578e-197 624.0
PYH3_k127_2178086_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004701 447.0
PYH3_k127_2178086_2 COG0476 Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002401 344.0
PYH3_k127_2178086_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007927 272.0
PYH3_k127_2178086_4 Pyrimidine 5''-nucleotidase K07025 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001317 258.0
PYH3_k127_2178086_5 Bacterial regulatory proteins, tetR family K05501 - - 0.00000000000000000000000000000000000000000000000000000000003411 210.0
PYH3_k127_2178086_6 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000004042 199.0
PYH3_k127_2178086_7 Sigma-70 region 2 K03088 - - 0.000000000000000000000000000000000000000000000000000003642 199.0
PYH3_k127_2178086_8 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000004986 153.0
PYH3_k127_2180042_0 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001611 590.0
PYH3_k127_2180042_1 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007898 269.0
PYH3_k127_2180042_2 dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes K01790 - 5.1.3.13 0.000001752 61.0
PYH3_k127_2182616_0 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 4.729e-209 658.0
PYH3_k127_2182616_1 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000208 340.0
PYH3_k127_2182616_10 Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB NOP family K03500 - 2.1.1.176 0.000000000000000000003041 101.0
PYH3_k127_2182616_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000001269 261.0
PYH3_k127_2182616_3 Belongs to the Dps family K04047 - - 0.00000000000000000000000000000000000000000000000000000000000000004979 229.0
PYH3_k127_2182616_4 TraB family K09973 - - 0.00000000000000000000000000000000000000000000000000000000007935 222.0
PYH3_k127_2182616_5 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000538 203.0
PYH3_k127_2182616_6 Belongs to the thioredoxin family K03671 - - 0.000000000000000000000000000000000000000000000006776 181.0
PYH3_k127_2182616_7 Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon K01894 - - 0.00000000000000000000000000000000000000000007523 166.0
PYH3_k127_2182616_8 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000001259 136.0
PYH3_k127_2182616_9 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000005327 130.0
PYH3_k127_2211229_0 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001107 516.0
PYH3_k127_2211229_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004266 400.0
PYH3_k127_2211229_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002507 355.0
PYH3_k127_2211229_3 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.0000000000000000000000000000000000000002095 156.0
PYH3_k127_2212727_0 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 1.889e-210 664.0
PYH3_k127_2212727_1 phosphate-selective porin O and P - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006229 475.0
PYH3_k127_2212727_2 Zinc-uptake complex component A periplasmic K02077 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 374.0
PYH3_k127_2212727_3 ABC-3 protein K02075 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004046 301.0
PYH3_k127_2212727_4 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 289.0
PYH3_k127_2212727_5 Belongs to the anti-sigma-factor antagonist family - - - 0.000000000000000000000000000000000000000000000000000008645 203.0
PYH3_k127_2212727_6 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000002371 115.0
PYH3_k127_2241783_0 ATPase related to phosphate starvation-inducible protein PhoH K07175 - - 6.08e-234 734.0
PYH3_k127_2241783_1 NAD(P)H-binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005201 545.0
PYH3_k127_2241783_10 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.000000000000000000005627 96.0
PYH3_k127_2241783_11 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 GO:0003674,GO:0003824,GO:0004601,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008379,GO:0009636,GO:0009987,GO:0016209,GO:0016491,GO:0016684,GO:0019725,GO:0033554,GO:0034599,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045454,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0051920,GO:0055114,GO:0065007,GO:0065008,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.11.1.15 0.0003116 44.0
PYH3_k127_2241783_2 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008605 514.0
PYH3_k127_2241783_3 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001664 397.0
PYH3_k127_2241783_4 Glycosyl transferase family 2 K10012 - 2.4.2.53 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004804 396.0
PYH3_k127_2241783_5 Alpha/beta hydrolase family K01561 - 3.8.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004542 365.0
PYH3_k127_2241783_6 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 350.0
PYH3_k127_2241783_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001127 257.0
PYH3_k127_2241783_8 Small Multidrug Resistance protein - - - 0.00000000000000000000000000000000000000000000000004281 186.0
PYH3_k127_2241783_9 Protein of unknown function DUF111 - - - 0.0000000000000000000000000000001221 129.0
PYH3_k127_2250941_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 5.656e-225 721.0
PYH3_k127_2250941_1 III protein, CoA-transferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003184 496.0
PYH3_k127_2250941_2 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000001435 226.0
PYH3_k127_2276411_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 5.04e-322 994.0
PYH3_k127_2276411_1 Exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 442.0
PYH3_k127_2276411_2 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001744 264.0
PYH3_k127_2276411_3 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000001208 187.0
PYH3_k127_2276411_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.000000000000000003081 96.0
PYH3_k127_2276411_5 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000002779 77.0
PYH3_k127_2292077_0 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 543.0
PYH3_k127_2292077_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 447.0
PYH3_k127_2292077_2 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000004419 141.0
PYH3_k127_2292077_3 helix_turn_helix multiple antibiotic resistance protein - - - 0.000000000000000171 83.0
PYH3_k127_2292077_4 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.00008782 48.0
PYH3_k127_2340552_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 607.0
PYH3_k127_2340552_1 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003264 412.0
PYH3_k127_2340552_2 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 GO:0000725,GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006310,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0007154,GO:0008047,GO:0008150,GO:0008152,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0030234,GO:0031668,GO:0033554,GO:0034641,GO:0042802,GO:0043085,GO:0043170,GO:0044093,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496,GO:0071704,GO:0090304,GO:0097159,GO:0098772,GO:1901360,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000128 209.0
PYH3_k127_2355278_0 response regulator K07715 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 531.0
PYH3_k127_2355278_1 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis K00560 - 2.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003109 439.0
PYH3_k127_2355278_2 Protein kinase domain K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000783 247.0
PYH3_k127_2372678_0 Methylmalonyl-CoA mutase K01847,K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 1.276e-270 847.0
PYH3_k127_2372678_1 COG1960 Acyl-CoA dehydrogenases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008777 598.0
PYH3_k127_2372678_2 AMP-binding enzyme C-terminal domain K00666 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 407.0
PYH3_k127_2372678_3 B12 binding domain K01849,K20907 - 5.4.99.2,5.4.99.64 0.000000000000000000000000000000000000000000000000000009068 209.0
PYH3_k127_2372678_4 CO dehydrogenase flavoprotein C-terminal domain K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000002142 188.0
PYH3_k127_2373758_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1144.0
PYH3_k127_2373758_1 Belongs to the glutamate--cysteine ligase type 1 family. Type 1 subfamily K01919 - 6.3.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004923 584.0
PYH3_k127_2373758_2 Zinc-binding dehydrogenase K00001 GO:0001505,GO:0003008,GO:0003674,GO:0003824,GO:0004022,GO:0004552,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0007610,GO:0007611,GO:0007612,GO:0007632,GO:0008150,GO:0008152,GO:0008306,GO:0008542,GO:0009314,GO:0009416,GO:0009628,GO:0016491,GO:0016614,GO:0016616,GO:0016651,GO:0016657,GO:0019222,GO:0031323,GO:0031399,GO:0032268,GO:0032501,GO:0044281,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0050877,GO:0050890,GO:0050896,GO:0051171,GO:0051246,GO:0051903,GO:0055114,GO:0060255,GO:0065007,GO:0065008,GO:0071704,GO:0080007,GO:0080090,GO:0080164,GO:1901615,GO:2000169,GO:2000377 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000007108 275.0
PYH3_k127_2373758_3 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.000000000000000000000000000001416 130.0
PYH3_k127_2418437_0 PFAM carboxyl transferase K01615 - 4.1.1.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 586.0
PYH3_k127_2418437_1 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 540.0
PYH3_k127_2418437_2 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004461 544.0
PYH3_k127_2418437_3 PAP2 superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008454 305.0
PYH3_k127_2418437_4 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000463 177.0
PYH3_k127_2418437_5 Cupin domain - - - 0.0000000000000000000000000000000000000216 151.0
PYH3_k127_2418437_6 GYD domain - - - 0.000000000000000000000000000005829 121.0
PYH3_k127_2418437_7 Sulfite exporter TauE/SafE - - - 0.000000000000008867 78.0
PYH3_k127_2436601_0 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004971 473.0
PYH3_k127_2436601_1 Pyridoxamine 5'-phosphate oxidase K07005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002059 259.0
PYH3_k127_2436601_2 Belongs to the MtfA family K09933 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004538 261.0
PYH3_k127_2436601_3 Solute carrier family 35 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000005239 254.0
PYH3_k127_2495944_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 7.535e-280 876.0
PYH3_k127_2495944_1 Histone deacetylase domain K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 327.0
PYH3_k127_2495944_2 glycolate oxidase iron-sulfur subunit K11473 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005518 312.0
PYH3_k127_2496001_0 Belongs to the malate synthase family K01638 - 2.3.3.9 5.891e-241 755.0
PYH3_k127_2496001_1 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002895 561.0
PYH3_k127_2496001_2 Two component, sigma54 specific, transcriptional regulator, Fis family K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001428 495.0
PYH3_k127_2496001_3 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005849 486.0
PYH3_k127_2496001_4 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002936 362.0
PYH3_k127_2496001_5 glycosyl transferase K12983,K12988,K19354 - - 0.000000000000000000000000000000000000000000006054 177.0
PYH3_k127_2496001_6 Glutathione S-transferase, C-terminal domain K11209 - - 0.00000000000000000000000000000000000007677 160.0
PYH3_k127_2496001_7 Domain of unknown function (DUF4124) - - - 0.000000000000000000000000001946 121.0
PYH3_k127_2501201_0 Protein of unknown function (DUF1302) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 512.0
PYH3_k127_2501201_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000005222 239.0
PYH3_k127_2501201_2 general secretion pathway protein G K02456 - - 0.00000000000000000000000000000000000000000000000000000000008402 206.0
PYH3_k127_2501201_3 Sigma factor PP2C-like phosphatases K07315,K07680 - 2.7.13.3,3.1.3.3 0.0000000000000000000000000000000000000000000000000000000114 224.0
PYH3_k127_2501201_4 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000002965 194.0
PYH3_k127_2501201_5 sigma factor antagonist activity K04757 - 2.7.11.1 0.000000000000000000000000000000009958 132.0
PYH3_k127_2501201_6 PFAM Sulfate transporter antisigma-factor antagonist STAS - - - 0.000000000000000000000004461 109.0
PYH3_k127_2501201_7 Type II secretion system (T2SS), protein F K02455 - - 0.0000000000000000832 83.0
PYH3_k127_2501201_8 - - - - 0.00000002243 65.0
PYH3_k127_2501201_9 Secretin and TonB N terminus short domain K02453 - - 0.00001202 57.0
PYH3_k127_251689_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 406.0
PYH3_k127_251689_1 with Pas Pac - - - 0.0000000000000000000000000000000006283 134.0
PYH3_k127_251689_2 Alpha beta hydrolase K01563 - 3.8.1.5 0.00000000000000000000002592 100.0
PYH3_k127_2526220_0 type II secretion system protein E K02454,K02504,K02652,K12276 - - 1.948e-257 805.0
PYH3_k127_2526220_1 type II secretion system protein K02653 - - 0.0000000000000000000000000000000000003337 144.0
PYH3_k127_2529687_0 Amidohydrolase family - - - 4.044e-232 730.0
PYH3_k127_2529687_1 Methionine synthase K00549 - 2.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005039 420.0
PYH3_k127_2529687_2 Protein involved in meta-pathway of phenol degradation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007048 361.0
PYH3_k127_2529687_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 358.0
PYH3_k127_2529687_4 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K04098 - 1.13.11.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 330.0
PYH3_k127_2529687_5 D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain K12972 - 1.1.1.79,1.1.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 296.0
PYH3_k127_2529687_6 Bacterial protein of unknown function (DUF899) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000009521 263.0
PYH3_k127_2529687_7 SCO1/SenC K07152 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001776 249.0
PYH3_k127_2529687_8 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000003088 224.0
PYH3_k127_2543695_0 COG0457 FOG TPR repeat - - - 9.276e-222 699.0
PYH3_k127_2543695_1 AMP-binding enzyme C-terminal domain K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 398.0
PYH3_k127_2543695_2 Glutathione-dependent formaldehyde-activating enzyme - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002404 291.0
PYH3_k127_2543695_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001329 312.0
PYH3_k127_2543695_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008601 274.0
PYH3_k127_2543695_5 Flavin reductase like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009997 251.0
PYH3_k127_2543695_6 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000001769 172.0
PYH3_k127_2543695_7 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000002839 168.0
PYH3_k127_2543695_9 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0001919 44.0
PYH3_k127_2546461_0 TIGRFAM PQQ-dependent dehydrogenase, methanol ethanol family - - - 2.63e-296 916.0
PYH3_k127_2546461_1 Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding K07303 - 1.3.99.16 3.989e-263 837.0
PYH3_k127_2546461_2 Belongs to the aldehyde dehydrogenase family K00135 - 1.2.1.16,1.2.1.20,1.2.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 512.0
PYH3_k127_2546461_3 2Fe-2S -binding domain protein K07302 - 1.3.99.16 0.00000000000000000000000000000000000000000000000000000000000000000000154 239.0
PYH3_k127_2546461_4 alpha beta - - - 0.00000000000000000000000000000000000000000000000000000000002718 215.0
PYH3_k127_2546461_5 Bacterial extracellular solute-binding proteins, family 3 - - - 0.000000000000000000000000000000000000000000000000000000003459 213.0
PYH3_k127_2546461_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000003515 107.0
PYH3_k127_2565886_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 2.169e-226 719.0
PYH3_k127_2565886_1 - - - - 0.000000000000000000000000000000000000000002322 166.0
PYH3_k127_2565886_2 Type II secretion system (T2SS), protein F K02455 - - 0.000000000000000000000000000000000001107 140.0
PYH3_k127_2565886_3 - - - - 0.000000000006994 78.0
PYH3_k127_2650041_0 Cytochrome b(N-terminal)/b6/petB - - - 3.05e-241 773.0
PYH3_k127_2650041_1 Methyl-viologen-reducing hydrogenase, delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000629 396.0
PYH3_k127_2650041_2 Cytochrome C and Quinol oxidase polypeptide I - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000188 344.0
PYH3_k127_2650041_3 PFAM electron transport protein SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000007857 242.0
PYH3_k127_2650041_4 - - - - 0.0000000000000000000000000000000002311 145.0
PYH3_k127_2650041_5 - - - - 0.00000000000000000000001052 117.0
PYH3_k127_2650041_6 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000001044 85.0
PYH3_k127_2677402_0 Permease MlaE K02066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 420.0
PYH3_k127_2677402_1 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 404.0
PYH3_k127_2677402_2 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002411 377.0
PYH3_k127_2677402_3 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000761 336.0
PYH3_k127_2677402_4 VacJ family lipoprotein K04754 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008419 274.0
PYH3_k127_2677402_5 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000006199 223.0
PYH3_k127_2677402_6 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000000000000000274 201.0
PYH3_k127_2677402_7 abc transporter K02065 - - 0.0000000000000000000000000000000000000000001256 161.0
PYH3_k127_2677402_8 Belongs to the BolA IbaG family - - - 0.0000000000000000000000000000484 117.0
PYH3_k127_2677402_9 STAS domain K07122 - - 0.00000000000001631 77.0
PYH3_k127_2691387_0 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0006082,GO:0006520,GO:0006560,GO:0006561,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016620,GO:0016903,GO:0018130,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001873 539.0
PYH3_k127_2691387_1 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.0000000000000000000000000000000000000000103 170.0
PYH3_k127_2691387_2 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.00000000000000003924 87.0
PYH3_k127_2711609_0 PFAM FAD linked oxidase domain protein K00102,K00104,K03777 - 1.1.2.4,1.1.3.15,1.1.5.12 9.293e-230 727.0
PYH3_k127_2711609_1 FAD binding domain K11472 - - 0.00000000000000000000000001514 121.0
PYH3_k127_2712434_0 AcrB/AcrD/AcrF family - - - 0.0 1240.0
PYH3_k127_2712434_1 molybdenum cofactor K03831 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006529 274.0
PYH3_k127_2712434_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K18302 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000415 260.0
PYH3_k127_2712434_3 Belongs to the UPF0311 family - - - 0.00000000000000000000000000000000000000000000001654 175.0
PYH3_k127_2712434_4 Bacterial regulatory proteins, tetR family - - - 0.00000000000000166 83.0
PYH3_k127_2715276_0 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 437.0
PYH3_k127_2715276_1 PFAM 5-nucleotidase K01081 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004016 424.0
PYH3_k127_2715276_2 Adenylate and Guanylate cyclase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 354.0
PYH3_k127_2715276_3 Putative methyltransferase K03439 - 2.1.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001205 295.0
PYH3_k127_2715276_4 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000003655 182.0
PYH3_k127_2715276_5 OsmC-like protein - - - 0.0000000000000000000000000000000000000106 152.0
PYH3_k127_2715276_6 ThiS family K03154 - - 0.00000000000000000002463 92.0
PYH3_k127_2715276_7 Cupin superfamily (DUF985) K09705 - - 0.000000000000000001402 89.0
PYH3_k127_2715276_8 - - - - 0.0002433 53.0
PYH3_k127_2729232_0 CBS domain containing protein K06189 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006869 370.0
PYH3_k127_2729232_1 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009156 323.0
PYH3_k127_2752963_0 UvrD/REP helicase N-terminal domain K03657 - 3.6.4.12 1.707e-232 736.0
PYH3_k127_2752963_1 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005321 425.0
PYH3_k127_2752963_2 FKBP-type peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000001096 184.0
PYH3_k127_2752963_3 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000005032 87.0
PYH3_k127_2752963_4 - - - - 0.00000000000000004103 81.0
PYH3_k127_2755547_0 Type I phosphodiesterase / nucleotide pyrophosphatase - - - 2.622e-226 708.0
PYH3_k127_2755547_1 Epoxide hydrolase N terminus K01253 - 3.3.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 544.0
PYH3_k127_2755547_10 enoyl-CoA hydratase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000001732 197.0
PYH3_k127_2755547_11 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0002475 49.0
PYH3_k127_2755547_2 TatD related DNase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002548 505.0
PYH3_k127_2755547_3 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735,K19969 - 4.2.3.152,4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005796 493.0
PYH3_k127_2755547_4 Xylose isomerase domain protein TIM barrel - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005823 444.0
PYH3_k127_2755547_5 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003981 316.0
PYH3_k127_2755547_6 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003867 277.0
PYH3_k127_2755547_7 Belongs to the enoyl-CoA hydratase isomerase family K01692,K11264 - 4.1.1.41,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000046 271.0
PYH3_k127_2755547_8 UbiA prenyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000351 278.0
PYH3_k127_2755547_9 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000122 231.0
PYH3_k127_2766969_0 Selenium-binding protein K17285 - - 5.204e-222 693.0
PYH3_k127_2766969_1 AMP-binding enzyme C-terminal domain K00666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 477.0
PYH3_k127_2778353_0 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002748 404.0
PYH3_k127_2778353_1 RNA polymerase sigma K03089 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008728 356.0
PYH3_k127_2778353_2 Involved in biogenesis of respiratory and photosynthetic systems K07152 - - 0.0000000000000000000000000000000000000000000000000000000000000000002926 236.0
PYH3_k127_2778353_3 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.000000000000000000000000000000000001375 141.0
PYH3_k127_2778353_4 signal sequence binding - - - 0.000000000001429 68.0
PYH3_k127_2801856_0 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 466.0
PYH3_k127_2801856_1 Beta-lactamase superfamily domain K00784 - 3.1.26.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000719 437.0
PYH3_k127_2801856_2 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002736 331.0
PYH3_k127_2801856_3 Sigma 54 modulation protein / S30EA ribosomal protein - - - 0.000000000000000000000000000000000000000000000000000000000000101 218.0
PYH3_k127_2801856_4 TIGRFAM ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 0.00000000000000000000000000000000000000000001265 166.0
PYH3_k127_2801856_5 universal stress protein - - - 0.0000000000000000000000000000002849 130.0
PYH3_k127_2801856_6 dksA traR - - - 0.00000000000000000000000002374 113.0
PYH3_k127_280446_0 Belongs to the helicase family. UvrD subfamily K03582 - 3.1.11.5 3.695e-265 847.0
PYH3_k127_280446_1 ABC transporter - - - 6.153e-241 755.0
PYH3_k127_280446_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001187 290.0
PYH3_k127_280446_11 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001124 270.0
PYH3_k127_280446_12 Universal stress protein UspA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001859 259.0
PYH3_k127_280446_13 hydrolase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006778 247.0
PYH3_k127_280446_14 Glyoxalase bleomycin resistance - - - 0.00000000000000000000000000000000000000000000000000001838 190.0
PYH3_k127_280446_15 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.0000000000000000000000000000000000000000000000000002346 186.0
PYH3_k127_280446_16 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000003205 187.0
PYH3_k127_280446_17 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.000000000000000000000000000000000000000000004814 168.0
PYH3_k127_280446_18 response regulator - - - 0.00000000000000000000000000000000000000001188 163.0
PYH3_k127_280446_19 Redoxin - - - 0.0000000000000000000000000000000000000001737 156.0
PYH3_k127_280446_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.933e-237 738.0
PYH3_k127_280446_20 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family - - - 0.0000000000000000000000000000000000002459 148.0
PYH3_k127_280446_21 Cupin domain - - - 0.000000000000000000000000000000000001566 145.0
PYH3_k127_280446_22 Domain of unknown function (DUF1330) - - - 0.000000000000000000000000000001144 124.0
PYH3_k127_280446_23 PFAM ribosomal protein L31 K02909 - - 0.00000000000000000000000000002571 119.0
PYH3_k127_280446_3 PD-(D/E)XK nuclease superfamily K01144 - 3.1.11.5 2.671e-209 679.0
PYH3_k127_280446_4 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 3.939e-195 621.0
PYH3_k127_280446_5 Cysteine synthase A K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003953 423.0
PYH3_k127_280446_6 Putative cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002669 391.0
PYH3_k127_280446_7 COG0500 SAM-dependent methyltransferases K07755 - 2.1.1.137 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001501 386.0
PYH3_k127_280446_8 Putative esterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008982 327.0
PYH3_k127_280446_9 Belongs to the pirin family K06911 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001853 300.0
PYH3_k127_2850173_0 COG1902 NADH flavin oxidoreductases, Old Yellow Enzyme family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007456 461.0
PYH3_k127_2850173_1 Belongs to the UPF0271 (lamB) family K07160 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006269 320.0
PYH3_k127_2850173_2 Protein of unknown function (DUF3467) - - - 0.000000000000111 74.0
PYH3_k127_2853267_0 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005256 342.0
PYH3_k127_2853267_1 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004696 339.0
PYH3_k127_2853267_2 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000004873 119.0
PYH3_k127_2876834_0 Bacterial extracellular solute-binding protein K02012 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001051 465.0
PYH3_k127_2876834_1 Bacterial type II and III secretion system protein - - - 0.000000000000000000000000000000000000001824 155.0
PYH3_k127_2876834_2 NlpC/P60 family K19303 - - 0.00000000000000000000000000000000000001669 149.0
PYH3_k127_2876834_3 COG1178 ABC-type Fe3 transport system, permease component K02011 - - 0.0000000000000000000000000006532 114.0
PYH3_k127_2904164_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1176.0
PYH3_k127_2904164_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 1.637e-287 893.0
PYH3_k127_2904164_10 dehydratase - - - 0.000000000000000000000000000000000000000000000001487 185.0
PYH3_k127_2904164_11 PFAM NUDIX hydrolase K08310 - 3.6.1.67 0.0000000000000000000000000000000000000000000001823 184.0
PYH3_k127_2904164_12 Polyketide cyclase / dehydrase and lipid transport - - - 0.000000000000000000000000000000000000000001434 164.0
PYH3_k127_2904164_13 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000000000005106 143.0
PYH3_k127_2904164_14 Protein of unknown function (DUF2946) - - - 0.00000000000000000000000000000000007857 139.0
PYH3_k127_2904164_15 Ribonuclease K01167 - 3.1.27.3 0.00000000000000000000000000000004243 128.0
PYH3_k127_2904164_16 Putative regulatory protein - - - 0.00000000000000000000000000000385 121.0
PYH3_k127_2904164_17 Barstar (barnase inhibitor) - - - 0.000000000000000002757 89.0
PYH3_k127_2904164_18 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000004974 84.0
PYH3_k127_2904164_2 Catalyzes the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol K06131 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002198 416.0
PYH3_k127_2904164_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 377.0
PYH3_k127_2904164_4 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001614 329.0
PYH3_k127_2904164_5 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 287.0
PYH3_k127_2904164_6 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003397 257.0
PYH3_k127_2904164_7 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000003812 222.0
PYH3_k127_2904164_8 Haem-degrading - - - 0.00000000000000000000000000000000000000000000000000004308 192.0
PYH3_k127_2904164_9 N-terminal half of MaoC dehydratase - - - 0.00000000000000000000000000000000000000000000000000615 193.0
PYH3_k127_2924354_0 Di-haem cytochrome c peroxidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 462.0
PYH3_k127_2924354_1 SCO1 SenC K07152 - - 0.000000000000000000000000000000000000000000000000000000001658 206.0
PYH3_k127_2924354_2 EamA-like transporter family - - - 0.0000000000000000000000000000000374 136.0
PYH3_k127_2943075_0 poly(R)-hydroxyalkanoic acid synthase K03821 - - 7.306e-276 859.0
PYH3_k127_2943075_1 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969 - 6.4.1.4 5.28e-262 834.0
PYH3_k127_2943075_10 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002429 369.0
PYH3_k127_2943075_11 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002104 361.0
PYH3_k127_2943075_12 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001889 296.0
PYH3_k127_2943075_13 2-hydroxychromene-2-carboxylate isomerase K14584 - 5.99.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000002995 243.0
PYH3_k127_2943075_14 KR domain - - - 0.00000000000000000000000000000000000000000000000000006938 190.0
PYH3_k127_2943075_15 Thioesterase K07107,K12500 - - 0.00000000000000000000000000000000000000000000000004334 198.0
PYH3_k127_2943075_16 Transcriptional regulator - - - 0.000000000000000000000000000000000000002372 151.0
PYH3_k127_2943075_17 thiolester hydrolase activity K17362 - - 0.0000000000000000000000000004339 130.0
PYH3_k127_2943075_2 Acetyl propionyl-CoA carboxylase, alpha subunit K01968 - 6.4.1.4 1.04e-236 751.0
PYH3_k127_2943075_3 COG1960 Acyl-CoA dehydrogenases K00253 - 1.3.8.4 2.104e-202 634.0
PYH3_k127_2943075_4 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 609.0
PYH3_k127_2943075_5 COG1960 Acyl-CoA dehydrogenases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003156 531.0
PYH3_k127_2943075_6 AMP-binding enzyme K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005089 523.0
PYH3_k127_2943075_7 HMGL-like K01640 - 4.1.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003447 450.0
PYH3_k127_2943075_8 Beta-lactamase superfamily domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004986 387.0
PYH3_k127_2943075_9 Enoyl-CoA hydratase/isomerase K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000893 384.0
PYH3_k127_2946188_0 aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K00087,K03520,K04108 - 1.17.1.4,1.2.5.3,1.3.7.9 0.0 1057.0
PYH3_k127_2946188_1 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008201 550.0
PYH3_k127_2946188_2 protein involved in response to NO K07234 - - 0.00000000000002888 86.0
PYH3_k127_3056765_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.403e-287 890.0
PYH3_k127_3056765_1 Acetyl-coenzyme A synthetase N-terminus K01907 - 6.2.1.16 4.845e-284 888.0
PYH3_k127_3056765_10 Glutamate/Leucine/Phenylalanine/Valine dehydrogenase K00261 - 1.4.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000005975 264.0
PYH3_k127_3056765_11 Cytidylate kinase-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000002577 233.0
PYH3_k127_3056765_12 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.0000000000000000000000000000000000000000000000000000004869 194.0
PYH3_k127_3056765_13 CoA binding domain K09181 - - 0.000000000000000000000000000000000000000004305 161.0
PYH3_k127_3056765_14 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K05589 - - 0.0000000000000000000000000001096 117.0
PYH3_k127_3056765_15 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000009105 83.0
PYH3_k127_3056765_16 low-complexity proteins - - - 0.0000000000000984 82.0
PYH3_k127_3056765_2 electron transfer flavoprotein-ubiquinone oxidoreductase K00311 - 1.5.5.1 5.657e-280 872.0
PYH3_k127_3056765_3 homoserine dehydrogenase - - - 2.022e-209 659.0
PYH3_k127_3056765_4 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 550.0
PYH3_k127_3056765_5 Beta-eliminating lyase K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005833 462.0
PYH3_k127_3056765_6 Pyridoxal-phosphate dependent enzyme K01754 - 4.3.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 437.0
PYH3_k127_3056765_7 Glutathione S-transferase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002862 430.0
PYH3_k127_3056765_8 3-deoxy-D-manno-octulosonic acid 8-phosphate synthase K01627 - 2.5.1.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004723 441.0
PYH3_k127_3056765_9 Protein involved in biosynthesis of mitomycin antibiotics polyketide fumonisin K10674 - 1.14.11.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 388.0
PYH3_k127_3056975_0 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 513.0
PYH3_k127_3056975_1 extracellular solute-binding protein, family 5 - - - 0.000000000000000000000000000000000000000000000001535 176.0
PYH3_k127_3056975_2 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000009122 158.0
PYH3_k127_3057439_0 MMPL family - - - 0.0 1310.0
PYH3_k127_3057439_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 3.4e-226 728.0
PYH3_k127_3057439_2 Acyl-CoA dehydrogenase, C-terminal domain - - - 4.402e-199 634.0
PYH3_k127_3057439_3 CoA-transferase family III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004799 347.0
PYH3_k127_3057439_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002176 271.0
PYH3_k127_3057439_5 Cupin 2, conserved barrel - - - 0.00000000000000000000000000000000000000000000004701 171.0
PYH3_k127_3057439_6 Universal stress protein family - - - 0.00000000000000000000000000008811 122.0
PYH3_k127_3057439_7 Heavy-metal-associated domain K01533,K17686 - 3.6.3.4,3.6.3.54 0.000000009076 69.0
PYH3_k127_3066892_0 amino acid K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 585.0
PYH3_k127_3066892_1 Belongs to the peptidase S1C family K04691,K04772 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008492 442.0
PYH3_k127_3066892_10 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000009216 209.0
PYH3_k127_3066892_11 Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP K01496,K11755 GO:0000105,GO:0003674,GO:0003824,GO:0004635,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016787,GO:0016810,GO:0016814,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 3.5.4.19,3.6.1.31 0.00000000000000000000000000000000000000000000000000000000019 205.0
PYH3_k127_3066892_12 Nucleotide transport and metabolism Carbohydrate transport and metabolism General function prediction only K02503 - - 0.0000000000000000000000000000000000000000001248 168.0
PYH3_k127_3066892_13 Psort location Cytoplasmic, score K01523 - 3.6.1.31 0.0000000000000000000000000000000001167 138.0
PYH3_k127_3066892_14 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.00000000000000000000000000002696 120.0
PYH3_k127_3066892_15 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.0000000000000000000000005632 105.0
PYH3_k127_3066892_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 441.0
PYH3_k127_3066892_3 Alpha beta hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 418.0
PYH3_k127_3066892_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001535 412.0
PYH3_k127_3066892_5 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003321 385.0
PYH3_k127_3066892_6 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 380.0
PYH3_k127_3066892_7 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003465 364.0
PYH3_k127_3066892_8 ATPases associated with a variety of cellular activities K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002623 364.0
PYH3_k127_3066892_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 345.0
PYH3_k127_3086734_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1123.0
PYH3_k127_3086734_1 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003128 321.0
PYH3_k127_3086734_2 Transglutaminase-like superfamily - - - 0.0000000000000000000001949 100.0
PYH3_k127_3100155_0 Putative diguanylate phosphodiesterase - - - 1.825e-228 743.0
PYH3_k127_3100155_1 PFAM Sulfatase K01130 - 3.1.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 557.0
PYH3_k127_3100155_2 PFAM oxidoreductase FAD NAD(P)-binding domain protein K00528 - 1.18.1.2,1.19.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004785 286.0
PYH3_k127_3100155_3 Alpha/beta hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000000000009906 234.0
PYH3_k127_3100155_4 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000001667 221.0
PYH3_k127_3100155_5 deoxyhypusine monooxygenase activity K05384,K05386 - - 0.000000000000000000000000000000000000000003181 179.0
PYH3_k127_3100155_6 COG0457 FOG TPR repeat - - - 0.0000000000000000000000000001187 121.0
PYH3_k127_3100155_7 Protein of unknown function (DUF3301) - - - 0.000000000000000007103 85.0
PYH3_k127_3100155_8 - - - - 0.0000000003314 71.0
PYH3_k127_3100155_9 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.0000003597 53.0
PYH3_k127_3137314_0 GTP-binding protein TypA K06207 - - 2.13e-303 939.0
PYH3_k127_3137314_1 DEAD-box RNA helicase involved in ribosome assembly. Has RNA-dependent ATPase activity and unwinds double-stranded RNA K11927 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008026,GO:0008104,GO:0008150,GO:0008186,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032991,GO:0033036,GO:0035770,GO:0036464,GO:0042623,GO:0043186,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044424,GO:0044444,GO:0044464,GO:0045495,GO:0051179,GO:0060293,GO:0070035,GO:0140098,GO:1990904 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 535.0
PYH3_k127_3137314_2 phosphoribosylaminoimidazolesuccinocarboxamide synthase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003521 446.0
PYH3_k127_3137314_3 fructose-bisphosphate aldolase K01623 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001699 411.0
PYH3_k127_3137314_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007842 326.0
PYH3_k127_3137314_5 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 318.0
PYH3_k127_3137314_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.0000000000000000000000000000000000000000000000000002618 202.0
PYH3_k127_3137314_7 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 - 2.7.7.87 0.0000000000000000000001819 106.0
PYH3_k127_3199101_0 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs K12573 - - 7.804e-243 761.0
PYH3_k127_3199101_1 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 - 3.6.4.12 2.132e-198 627.0
PYH3_k127_3199101_10 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000000001504 136.0
PYH3_k127_3199101_11 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.00000000000000000000000000000000002129 137.0
PYH3_k127_3199101_12 Binds single-stranded DNA at the primosome assembly site (PAS) K02686 - - 0.000000000000003526 84.0
PYH3_k127_3199101_2 Protein of unknown function (DUF1254) - - - 3.01e-196 614.0
PYH3_k127_3199101_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003154 433.0
PYH3_k127_3199101_4 Large family of predicted nucleotide-binding domains K07175 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002577 360.0
PYH3_k127_3199101_5 Specifically methylates the ribose of guanosine 2251 in 23S rRNA K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003828 293.0
PYH3_k127_3199101_6 Histone methylation protein DOT1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000008511 261.0
PYH3_k127_3199101_7 binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000000000000000000000001139 212.0
PYH3_k127_3199101_8 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.00000000000000000000000000000000000000000000000000000000008403 209.0
PYH3_k127_3199101_9 FecR protein - - - 0.000000000000000000000000000000000000000001708 166.0
PYH3_k127_3205739_0 PFAM PfkB domain protein K00852,K00856 - 2.7.1.15,2.7.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 436.0
PYH3_k127_3205739_1 Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP K01525 - 3.6.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005157 335.0
PYH3_k127_3205739_2 COG0537 Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases K02503 - - 0.00000000000000000000000000000000000000000000003448 173.0
PYH3_k127_3205739_3 TIGRFAM MJ0042 family finger-like protein - - - 0.000000000000000000000000000000000007821 140.0
PYH3_k127_3205739_4 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 0.0000000000000000000000000001639 117.0
PYH3_k127_3256349_0 Enoyl-CoA hydratase/isomerase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009352 440.0
PYH3_k127_3256349_1 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001105 352.0
PYH3_k127_3256349_2 Competence protein ComEC Rec2 K02238 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000005349 259.0
PYH3_k127_3256349_3 Dodecin K09165 - - 0.000000000000000000005875 96.0
PYH3_k127_3335412_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006871 394.0
PYH3_k127_3335412_1 cell division ATP-binding protein FtsE K09812 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0008144,GO:0008150,GO:0009898,GO:0009987,GO:0016020,GO:0017076,GO:0019897,GO:0019898,GO:0030554,GO:0031234,GO:0032153,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042221,GO:0043167,GO:0043168,GO:0044424,GO:0044425,GO:0044459,GO:0044464,GO:0046677,GO:0050896,GO:0051301,GO:0071944,GO:0097159,GO:0097367,GO:0098552,GO:0098562,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000116 233.0
PYH3_k127_3335412_2 Part of the ABC transporter FtsEX involved in cellular division K09811 - - 0.0000000000003052 73.0
PYH3_k127_3346252_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1180.0
PYH3_k127_3346252_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895,K01907 - 6.2.1.1,6.2.1.16 1.889e-259 816.0
PYH3_k127_3346252_10 Phospholipase/Carboxylesterase K06999 - - 0.0000000000000000000000000000000000008014 148.0
PYH3_k127_3346252_2 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 7.987e-224 727.0
PYH3_k127_3346252_3 Belongs to the TPP enzyme family K01652 - 2.2.1.6 2.985e-206 654.0
PYH3_k127_3346252_4 ABC transporter K10004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 411.0
PYH3_k127_3346252_5 Bacterial periplasmic substrate-binding proteins K02030,K10001 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 375.0
PYH3_k127_3346252_6 TIGRFAM amine acid ABC transporter, permease protein, 3-TM region, His Glu Gln Arg opine family K10002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 337.0
PYH3_k127_3346252_7 TIGRFAM polar amino acid ABC transporter, inner membrane subunit K10003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001307 314.0
PYH3_k127_3346252_8 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.00000000000000000000000000000000000000000000000000000000001986 217.0
PYH3_k127_3346252_9 Domain of unknown function (DUF4442) - - - 0.000000000000000000000000000000000000000000000000001848 186.0
PYH3_k127_3362784_0 Belongs to the beta-ketoacyl-ACP synthases family K09458 - 2.3.1.179 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004332 565.0
PYH3_k127_3362784_1 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 462.0
PYH3_k127_3362784_2 Belongs to the beta-ketoacyl-ACP synthases family K00647 - 2.3.1.41 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002141 445.0
PYH3_k127_3362784_3 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 332.0
PYH3_k127_3362784_4 MMPL family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 300.0
PYH3_k127_3362784_5 PFAM Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA FabZ - - - 0.0000000000000000000000000000000000009993 149.0
PYH3_k127_3362784_6 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.00000000000000000000000000000003234 126.0
PYH3_k127_3362784_8 Protein of unknown function (DUF3261) - - - 0.000002154 60.0
PYH3_k127_3369901_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003418 576.0
PYH3_k127_3369901_1 YqeY-like protein K09117 - - 0.000000000000000000000000000000000000000000000001154 182.0
PYH3_k127_3369901_2 Belongs to the bacterial ribosomal protein bS21 family K02970 - - 0.00000000000000000000000000001787 123.0
PYH3_k127_3369901_3 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000048 103.0
PYH3_k127_3381066_0 PFAM L-carnitine dehydratase bile acid-inducible protein F - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 486.0
PYH3_k127_3381066_1 PFAM conserved - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006992 422.0
PYH3_k127_3381066_10 PFAM major facilitator superfamily MFS_1 - - - 0.0000001224 64.0
PYH3_k127_3381066_11 DNA-sulfur modification-associated - - - 0.000001013 61.0
PYH3_k127_3381066_2 cytochrome p450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003346 414.0
PYH3_k127_3381066_3 C-terminal region of band_7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 399.0
PYH3_k127_3381066_4 Carboxymuconolactone decarboxylase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007094 259.0
PYH3_k127_3381066_5 2-keto-4-pentenoate hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000002837 226.0
PYH3_k127_3381066_6 Protein of unknown function (DUF1223) - - - 0.000000000000000000000000000000000000000000000000000000000001048 221.0
PYH3_k127_3381066_7 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.0000000000000000000000000000000007799 134.0
PYH3_k127_3381066_8 Haem-binding uptake, Tiki superfamily, ChaN - - - 0.0000000000000002054 81.0
PYH3_k127_3381066_9 NfeD-like C-terminal, partner-binding - - - 0.00000000000005109 78.0
PYH3_k127_3382604_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007341 371.0
PYH3_k127_3382604_1 gag-polyprotein putative aspartyl protease - - - 0.0000000000000000000000000000000000001132 157.0
PYH3_k127_3401695_0 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 547.0
PYH3_k127_3401695_1 Amidohydrolase K01686 - 4.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000003651 245.0
PYH3_k127_3401695_2 RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs K03666 - - 0.00000000000000000000000000000000000156 138.0
PYH3_k127_3411561_0 Pyruvate ferredoxin/flavodoxin oxidoreductase K04090 - 1.2.7.8 0.0 1560.0
PYH3_k127_3411561_1 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 3.888e-207 647.0
PYH3_k127_3411561_2 transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007709 271.0
PYH3_k127_3411561_3 Related to pyridoxine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000001318 235.0
PYH3_k127_3441573_0 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 368.0
PYH3_k127_3441573_1 Amidase K01426 - 3.5.1.4 0.0000000000000000000002082 98.0
PYH3_k127_3445750_0 serine threonine protein kinase K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008174 523.0
PYH3_k127_3445750_1 argininosuccinate lyase K01755 - 4.3.2.1 0.00000000000000005929 81.0
PYH3_k127_3447242_0 Long-chain acyl-CoA synthetases (AMP-forming) K01897 - 6.2.1.3 3.564e-292 909.0
PYH3_k127_3447242_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 2.321e-209 659.0
PYH3_k127_3447242_2 Coenzyme F390 synthetase K01912 - 6.2.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007252 524.0
PYH3_k127_3447242_3 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 505.0
PYH3_k127_3447242_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005175 465.0
PYH3_k127_3447242_5 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 460.0
PYH3_k127_3447242_6 branched-chain amino acid K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007357 428.0
PYH3_k127_3447242_7 COG0411 ABC-type branched-chain amino acid transport systems, ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 430.0
PYH3_k127_3447242_8 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity K01607 - 4.1.1.44 0.0000000000002344 70.0
PYH3_k127_3448379_0 Permease, YjgP YjgQ family K11720 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003535 383.0
PYH3_k127_3448379_1 Permease YjgP YjgQ family K07091 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003749 369.0
PYH3_k127_3448379_2 Protein of unknown function (DUF3106) - - - 0.0000000000000000000000003027 114.0
PYH3_k127_3448379_3 RDD family - - - 0.000000000000000000000007608 112.0
PYH3_k127_3448379_4 Protein of unknown function (DUF3619) - - - 0.000000000001562 70.0
PYH3_k127_3463360_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 7.693e-248 778.0
PYH3_k127_3463360_1 RNB K01147 - 3.1.13.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008109 621.0
PYH3_k127_3463360_2 Reutilizes the intact tripeptide L-alanyl-gamma-D- glutamyl-meso-diaminopimelate by linking it to UDP-N- acetylmuramate K02558 - 6.3.2.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005562 606.0
PYH3_k127_3463360_3 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000001727 198.0
PYH3_k127_3463360_4 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000006918 187.0
PYH3_k127_3463360_5 Uncharacterised protein family (UPF0227) K07000 - - 0.00000000000000000000000000000000000000000000000003516 186.0
PYH3_k127_3463360_6 - - - - 0.000000000000000000000000000000000000000000005515 170.0
PYH3_k127_3463360_7 Redoxin family - - - 0.00000000000000000000000000000000001199 146.0
PYH3_k127_3463360_8 COG0810 Periplasmic protein TonB, links inner and outer membranes K03832 - - 0.0000000000000000000000002332 110.0
PYH3_k127_3463360_9 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000002562 95.0
PYH3_k127_3481175_0 AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.296e-256 815.0
PYH3_k127_3481175_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 517.0
PYH3_k127_3481175_2 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 471.0
PYH3_k127_3481175_3 Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007928 469.0
PYH3_k127_3481175_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001643 410.0
PYH3_k127_3481175_5 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001144 387.0
PYH3_k127_3481175_6 branched-chain amino acid transport K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 356.0
PYH3_k127_3481175_7 Thioesterase superfamily - - - 0.000000000000000000000000000004241 137.0
PYH3_k127_3481175_8 Biotin carboxylase C-terminal domain K01968,K13777 - 6.4.1.4,6.4.1.5 0.000000000000001053 79.0
PYH3_k127_3481175_9 PFAM acyl-CoA dehydrogenase domain protein K09456 - - 0.00000005215 58.0
PYH3_k127_3508600_0 ABC transporter transmembrane region K02021 - - 2.685e-272 865.0
PYH3_k127_3508600_1 Oligopeptide/dipeptide transporter, C-terminal region K02031,K02032 - - 5.466e-259 814.0
PYH3_k127_3508600_10 sulfite oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000526 432.0
PYH3_k127_3508600_11 Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities K00842,K14155 - 4.4.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 390.0
PYH3_k127_3508600_12 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004004 394.0
PYH3_k127_3508600_13 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 376.0
PYH3_k127_3508600_14 Pfam:Kce - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007047 367.0
PYH3_k127_3508600_15 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 361.0
PYH3_k127_3508600_16 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 369.0
PYH3_k127_3508600_17 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007484 266.0
PYH3_k127_3508600_18 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000008162 235.0
PYH3_k127_3508600_19 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000000000005174 221.0
PYH3_k127_3508600_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 2.115e-252 794.0
PYH3_k127_3508600_20 OsmC-like protein K07397 - - 0.0000000000000000000000000000000000000000000000000000000000002221 215.0
PYH3_k127_3508600_21 Required for insertion of 4Fe-4S clusters K15724 - - 0.000000000000000000000000000000000000000000000000000000000000372 216.0
PYH3_k127_3508600_22 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.000000000000000000000000000000000000000000000000000000000002794 210.0
PYH3_k127_3508600_23 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K06034 - 4.1.1.79 0.000000000000000000000000000000000000000000000000000000000008411 213.0
PYH3_k127_3508600_24 - - - - 0.0000000000000000000000000000000000000000000000005581 189.0
PYH3_k127_3508600_25 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000000000000000000001021 177.0
PYH3_k127_3508600_26 polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000008336 172.0
PYH3_k127_3508600_27 Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides K07232 - - 0.000000000000000000000000000000000000000003589 171.0
PYH3_k127_3508600_28 cyclic nucleotide-binding - - - 0.00000000000000000000000000000000000009594 148.0
PYH3_k127_3508600_29 - - - - 0.0000000000000000000000000000000001483 139.0
PYH3_k127_3508600_3 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.026e-197 627.0
PYH3_k127_3508600_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003234 602.0
PYH3_k127_3508600_5 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008742 563.0
PYH3_k127_3508600_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002207 551.0
PYH3_k127_3508600_7 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002418 528.0
PYH3_k127_3508600_8 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001174 514.0
PYH3_k127_3508600_9 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 462.0
PYH3_k127_352153_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS K01881 - 6.1.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007796 385.0
PYH3_k127_352153_1 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000297 287.0
PYH3_k127_352153_2 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001649 259.0
PYH3_k127_352153_3 Protein of unknown function (DUF3501) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002889 248.0
PYH3_k127_352153_4 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.00000000000000000000000000000000005084 135.0
PYH3_k127_352153_5 CNP1-like family - - - 0.00000000000000000000000000006402 128.0
PYH3_k127_352332_0 Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2-amino-butenoic acid K18235 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008395 391.0
PYH3_k127_352332_1 probably involved in intracellular septation K06190 - - 0.00000000000000000000000000000000000000000000000000000000000000000002404 236.0
PYH3_k127_352332_2 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000004773 214.0
PYH3_k127_352332_3 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000001192 217.0
PYH3_k127_352332_4 Alanine acetyltransferase - - - 0.000000000000000000000000000000000000000000000000000001083 196.0
PYH3_k127_352332_6 GYD domain - - - 0.00000000000000000207 90.0
PYH3_k127_352332_7 Ankyrin repeat - - - 0.000000000000007791 88.0
PYH3_k127_358053_0 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008537 495.0
PYH3_k127_358053_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005086 463.0
PYH3_k127_358053_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000753 422.0
PYH3_k127_358053_3 Belongs to the GST superfamily K11209 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009047 312.0
PYH3_k127_358053_4 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001456 306.0
PYH3_k127_358053_5 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001737 306.0
PYH3_k127_358053_6 Alpha beta hydrolase K00433 - 1.11.1.10 0.0000000000000000000000000000000000000000000000000000000000000000006668 245.0
PYH3_k127_358053_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000001178 227.0
PYH3_k127_3582189_0 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.521e-242 777.0
PYH3_k127_3582189_1 Endoribonuclease L-PSP - - - 0.00000000000000000000000000000000000000000000000006233 180.0
PYH3_k127_3582189_2 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000001042 119.0
PYH3_k127_3582189_3 Tetratricopeptide repeat - - - 0.000000000000000005787 86.0
PYH3_k127_3597998_0 5'-nucleotidase K01081 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 412.0
PYH3_k127_3597998_1 AsmA family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 430.0
PYH3_k127_360322_0 Exopolysaccharide biosynthesis protein YbjH - - - 1.281e-214 698.0
PYH3_k127_3638864_0 Neisseria PilC beta-propeller domain K02674 - - 2.836e-210 704.0
PYH3_k127_3638864_1 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002103 459.0
PYH3_k127_3638864_10 Pilus assembly protein PilX - - - 0.0000000000000000000000000000405 124.0
PYH3_k127_3638864_11 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000001106 112.0
PYH3_k127_3638864_12 Type II transport protein GspH K08084 - - 0.000000000000000000000001058 111.0
PYH3_k127_3638864_13 Thioesterase superfamily K01075 - 3.1.2.23 0.0000000005616 67.0
PYH3_k127_3638864_2 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003129 400.0
PYH3_k127_3638864_3 Methionine synthase K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001735 342.0
PYH3_k127_3638864_4 CoA-transferase family III K07749 - 2.8.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007854 315.0
PYH3_k127_3638864_5 FMN-dependent dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002504 289.0
PYH3_k127_3638864_6 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000003392 252.0
PYH3_k127_3638864_7 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000005111 241.0
PYH3_k127_3638864_8 type 4 fimbrial biogenesis K02672 - - 0.000000000000000000000000000000000000000000000000000000000000000002871 238.0
PYH3_k127_3638864_9 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000000000000000000000008972 157.0
PYH3_k127_3641291_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003087 376.0
PYH3_k127_3641291_1 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K01420 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007435 324.0
PYH3_k127_3641291_2 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000006395 236.0
PYH3_k127_3641291_3 Pfam Response regulator receiver - - - 0.0000000000001682 75.0
PYH3_k127_3686515_0 Arginyl-tRNA synthetase K01887 - 6.1.1.19 6.497e-204 647.0
PYH3_k127_3686515_1 cell division protein - - - 0.00000005527 57.0
PYH3_k127_3722150_0 NADPH quinone oxidoreductase K00344 - 1.6.5.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008145 457.0
PYH3_k127_3722150_1 PFAM short-chain dehydrogenase reductase SDR - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004394 409.0
PYH3_k127_3722150_2 Cupin 2, conserved barrel domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 327.0
PYH3_k127_3722150_3 7TM diverse intracellular signalling - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 330.0
PYH3_k127_3722150_4 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001522 282.0
PYH3_k127_3722150_5 DSBA-like thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004926 273.0
PYH3_k127_3722150_6 Protein of unknown function (DUF2892) - - - 0.000000000000000000523 94.0
PYH3_k127_3722150_7 NUDIX hydrolase - - - 0.0007921 51.0
PYH3_k127_373858_0 RHS Repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002869 528.0
PYH3_k127_373858_1 nitrite transmembrane transporter activity K08218,K08223 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008581 497.0
PYH3_k127_373858_2 TIGRFAM RHS repeat-associated core domain - - - 0.000000000000000000000000000000000000001146 164.0
PYH3_k127_373858_3 Bacterial protein of unknown function (DUF883) - - - 0.000000000000000000000000000000000007869 141.0
PYH3_k127_373858_4 Putative Actinobacterial Holin-X, holin superfamily III - - - 0.00000000000000001758 87.0
PYH3_k127_3778704_0 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00525 GO:0000166,GO:0003674,GO:0003824,GO:0004748,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005971,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009262,GO:0009263,GO:0009987,GO:0016491,GO:0016725,GO:0016728,GO:0018130,GO:0019438,GO:0019637,GO:0032991,GO:0034641,GO:0034654,GO:0036094,GO:0042802,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0046483,GO:0055086,GO:0055114,GO:0061731,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901137,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902494,GO:1990204 1.17.4.1 0.0 1440.0
PYH3_k127_3778704_1 Sigma-54 interaction domain protein K02667 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004374 379.0
PYH3_k127_3778704_2 Ami_2 K03806 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000002155 227.0
PYH3_k127_3804671_0 Fe-S oxidoreductase K21834 - - 4.262e-251 784.0
PYH3_k127_3804671_1 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008505 494.0
PYH3_k127_3804671_2 NADPH-dependent glutamate synthase beta - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 438.0
PYH3_k127_3804671_3 Nitrate reductase gamma subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007712 350.0
PYH3_k127_3804671_4 sulfur relay protein TusD DsrE K07235 - - 0.0000000000000000000000000000000000000000000000000000000000006119 211.0
PYH3_k127_3804671_5 part of a sulfur-relay system K11179 - - 0.000000000000000000000000000000000000000000000000000000005565 199.0
PYH3_k127_3804671_6 Sulfur relay protein TusC DsrF K07236 - - 0.0000000000000000000000000000000000000000000000000008196 190.0
PYH3_k127_3804671_7 DsrH like protein K07237 - - 0.000000000000000000000000000000001948 138.0
PYH3_k127_3859591_0 KR domain K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 332.0
PYH3_k127_3859591_1 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000002411 213.0
PYH3_k127_3860075_0 Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002625 380.0
PYH3_k127_3860075_1 One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA K03071 - - 0.0000000000000000000000000000000000000000000000001441 185.0
PYH3_k127_3860075_2 transcriptional - - - 0.000000000000000000000000000000000000000003408 161.0
PYH3_k127_3860075_3 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000001976 150.0
PYH3_k127_3860075_4 Bacterial SH3 domain - - - 0.00000000000000000000000000000000002427 139.0
PYH3_k127_3860075_5 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins K03676 - - 0.0000000000000000000000000001674 119.0
PYH3_k127_3870550_0 Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL CutL-like protein K07303 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000734 552.0
PYH3_k127_3885162_0 Transglycosylase SLT domain K08305 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 336.0
PYH3_k127_3885162_1 Lysin motif K06194 - - 0.0000000000000000000000000000000000000000000000000005356 189.0
PYH3_k127_3892983_0 glutamine synthetase K01915,K20712 GO:0003674,GO:0003824,GO:0006725,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016866,GO:0034022,GO:0042537,GO:0044237,GO:0050486,GO:0071704,GO:1901360 5.4.4.3,6.3.1.2 1.535e-245 764.0
PYH3_k127_3892983_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.17 2.159e-215 670.0
PYH3_k127_3892983_2 Sigma-54 interaction domain K07712 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0019219,GO:0019222,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0043565,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:2000112,GO:2000113,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 435.0
PYH3_k127_3892983_3 serine threonine protein kinase K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004866 409.0
PYH3_k127_3892983_4 Signal transduction histidine kinase, nitrogen specific K07708 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 381.0
PYH3_k127_3892983_5 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002378 348.0
PYH3_k127_3892983_6 Serine aminopeptidase, S33 K06889 - - 0.0000000000000000000000000000000000000000000000000000002476 203.0
PYH3_k127_3892983_7 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000002048 188.0
PYH3_k127_3892983_8 Domain of unknown function (DUF4124) - - - 0.000000000000000000003074 100.0
PYH3_k127_3893127_0 PFAM sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 414.0
PYH3_k127_3893127_1 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000000000000000000009115 147.0
PYH3_k127_3893127_2 CBS domain containing protein - - - 0.0000004591 56.0
PYH3_k127_3893127_3 KR domain K19548 - 1.1.1.385 0.0007365 43.0
PYH3_k127_3934958_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.57e-233 728.0
PYH3_k127_3934958_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 GO:0003674,GO:0003824,GO:0003899,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006351,GO:0006354,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0032774,GO:0034062,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097659,GO:0097747,GO:0140098,GO:1901360,GO:1901362,GO:1901576 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007518 532.0
PYH3_k127_3934958_10 Ribosomal protein L17 K02879 - - 0.00000000000000000000000000000000000000000000000000001358 196.0
PYH3_k127_3934958_11 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.0000000000000000000000000000000000000000000000000001083 188.0
PYH3_k127_3934958_12 binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000002912 189.0
PYH3_k127_3934958_13 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000000000000000009286 181.0
PYH3_k127_3934958_14 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000002966 154.0
PYH3_k127_3934958_15 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000000006653 137.0
PYH3_k127_3934958_16 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000001487 134.0
PYH3_k127_3934958_17 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.0000000000000000000000000001668 119.0
PYH3_k127_3934958_18 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000003566 102.0
PYH3_k127_3934958_19 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.00000000000000000008734 89.0
PYH3_k127_3934958_2 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 372.0
PYH3_k127_3934958_20 Ribosomal protein L30 K02907 - - 0.00000000000000001867 84.0
PYH3_k127_3934958_21 NapD protein K02570 - - 0.00000000000002016 80.0
PYH3_k127_3934958_23 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K02572 - - 0.00000000000008982 75.0
PYH3_k127_3934958_24 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000006153 68.0
PYH3_k127_3934958_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003707 341.0
PYH3_k127_3934958_4 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009642 300.0
PYH3_k127_3934958_5 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006955 280.0
PYH3_k127_3934958_6 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001452 265.0
PYH3_k127_3934958_7 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000001287 220.0
PYH3_k127_3934958_8 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000001619 218.0
PYH3_k127_3934958_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000003567 216.0
PYH3_k127_3939038_0 ribonuclease, Rne Rng family K08301 - - 6.832e-226 717.0
PYH3_k127_3939038_1 Belongs to the amidase family K01426,K02433 - 3.5.1.4,6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002658 598.0
PYH3_k127_3939038_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006865 456.0
PYH3_k127_3939038_3 Belongs to the prokaryotic GSH synthase family K01920 - 6.3.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003771 319.0
PYH3_k127_3939038_4 Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 312.0
PYH3_k127_3939038_5 Maf-like protein K06287 - - 0.00000000000000000000000000000000000000000000000000000000000008266 222.0
PYH3_k127_3939038_6 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000002154 167.0
PYH3_k127_3939038_7 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.00000000000000003524 81.0
PYH3_k127_3966427_0 Aminotransferase K14261 - - 4.445e-221 689.0
PYH3_k127_3966427_1 Cysteine-rich domain - - - 1.384e-220 691.0
PYH3_k127_3966427_2 homoserine dehydrogenase K00003 - 1.1.1.3 1.177e-200 653.0
PYH3_k127_3966427_3 Threonine synthase K01733 - 4.2.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001446 611.0
PYH3_k127_3966427_4 cation transport ATPase K01533 - 3.6.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 353.0
PYH3_k127_3966427_5 PFAM glycosyl transferase family 39 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002394 349.0
PYH3_k127_3966427_6 Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes - - - 0.00000000000000000000000000000000000000000000000000132 194.0
PYH3_k127_3966427_7 Hsp20/alpha crystallin family - - - 0.00000000000000000000000000000000000000007202 155.0
PYH3_k127_3966427_8 Protein of unknown function (DUF498/DUF598) - - - 0.0000000000000000000000000000000007097 149.0
PYH3_k127_3966427_9 Vibrio cholerae RfbT protein - - - 0.00000000000000000004083 102.0
PYH3_k127_3968556_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1215.0
PYH3_k127_3968556_1 dna topoisomerase III K03169 - 5.99.1.2 0.0 1110.0
PYH3_k127_3968556_10 Domain of unknown function (DUF4390) - - - 0.00000000000000000000000000000000000000000000001035 181.0
PYH3_k127_3968556_11 Belongs to the Smg family K03747 - - 0.0000000000000000000000000000001804 131.0
PYH3_k127_3968556_12 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.00000000241 59.0
PYH3_k127_3968556_2 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006533 571.0
PYH3_k127_3968556_3 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000139 432.0
PYH3_k127_3968556_4 Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004948 436.0
PYH3_k127_3968556_5 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001912 385.0
PYH3_k127_3968556_6 PFAM Peptidoglycan-binding LysM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 355.0
PYH3_k127_3968556_7 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 344.0
PYH3_k127_3968556_8 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002526 275.0
PYH3_k127_3968556_9 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000001037 219.0
PYH3_k127_3999538_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 0.0 1115.0
PYH3_k127_3999538_1 Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the phosphoenolpyruvate synthase (PEPS) by catalyzing its phosphorylation dephosphorylation K09773 - 2.7.11.33,2.7.4.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 362.0
PYH3_k127_3999538_2 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000001955 229.0
PYH3_k127_3999538_3 Oligoketide cyclase lipid transport protein - - - 0.00000000000000000000000000000000000009867 146.0
PYH3_k127_3999538_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03437 - - 0.00000000000000003088 83.0
PYH3_k127_3999538_5 RnfH family Ubiquitin K09801 - - 0.0007563 44.0
PYH3_k127_4000507_0 Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation K00549 - 2.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004736 546.0
PYH3_k127_4000507_1 Rhodanese Homology Domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003084 528.0
PYH3_k127_4000507_10 NIPSNAP - - - 0.000000000000000000000000000000000000000000000007723 176.0
PYH3_k127_4000507_11 Cysteine dioxygenase type I - - - 0.00000000000000000000000000000000000000329 153.0
PYH3_k127_4000507_12 Cupin 2, conserved barrel K21700 - - 0.00000000000000000000000000000003508 133.0
PYH3_k127_4000507_2 Major facilitator superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 537.0
PYH3_k127_4000507_3 Protein of unknown function (DUF2817) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001846 423.0
PYH3_k127_4000507_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001567 402.0
PYH3_k127_4000507_5 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002325 324.0
PYH3_k127_4000507_6 Alpha/beta hydrolase family K01055 - 3.1.1.24 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002156 289.0
PYH3_k127_4000507_7 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000001285 263.0
PYH3_k127_4000507_8 type I phosphodiesterase nucleotide pyrophosphatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005323 250.0
PYH3_k127_4000507_9 Glycosyltransferase like family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000001938 224.0
PYH3_k127_4020411_0 Catalyzes cross-linking of the peptidoglycan cell wall at the division septum K03587 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006301 548.0
PYH3_k127_4020411_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 534.0
PYH3_k127_4020411_2 MraW methylase family K03438 - 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003117 365.0
PYH3_k127_4020411_3 Mammalian cell entry related domain protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005702 342.0
PYH3_k127_4020411_4 Permease MlaE - - - 0.0000000000000000000000000000000000000000000000000003867 192.0
PYH3_k127_4020411_5 Belongs to the MraZ family K03925 - - 0.0000000000000000000000000000000000000000541 157.0
PYH3_k127_4020411_6 - - - - 0.00000000000000000000000000000000000000005851 169.0
PYH3_k127_4020411_7 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic K03586 - - 0.00000000000000000000005921 101.0
PYH3_k127_403014_0 ABC transporter K15738 - - 2.943e-216 684.0
PYH3_k127_403014_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007416 404.0
PYH3_k127_403014_2 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.000000000000002381 89.0
PYH3_k127_403014_3 Major Facilitator Superfamily K19577 - - 0.000000000008134 70.0
PYH3_k127_4130648_0 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005971 426.0
PYH3_k127_4130648_1 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 299.0
PYH3_k127_4130648_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009215 255.0
PYH3_k127_4130648_3 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000001883 104.0
PYH3_k127_4189769_0 Hydantoinase/oxoprolinase N-terminal region K01473 - 3.5.2.14 3.373e-284 889.0
PYH3_k127_4189769_1 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007203 572.0
PYH3_k127_4189769_2 GntR family - - - 0.00000302 52.0
PYH3_k127_421730_0 Patatin-like phospholipase K07001 - - 6.772e-267 837.0
PYH3_k127_421730_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 6.33e-209 655.0
PYH3_k127_421730_2 Glutathione S-transferase K03599 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001922 325.0
PYH3_k127_421730_3 Cytochrome C1 family K00413 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001373 289.0
PYH3_k127_421730_4 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000002638 259.0
PYH3_k127_421730_5 stringent starvation protein B K03600 - - 0.000000000000000000000000000000000000000001803 160.0
PYH3_k127_421730_6 Trypsin-like serine proteases typically periplasmic contain C-terminal PDZ domain K04691,K04772 - - 0.000000002291 59.0
PYH3_k127_424362_0 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002189 362.0
PYH3_k127_424362_1 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000007399 260.0
PYH3_k127_424362_2 PFAM NnrS family protein K07234 - - 0.000000000000000000000000000000000000000000008469 181.0
PYH3_k127_4251296_0 l-serine dehydratase K01752 - 4.3.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002622 537.0
PYH3_k127_4251296_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000009821 162.0
PYH3_k127_4251296_2 Bacterial extracellular solute-binding protein, family 7 K21395 - - 0.000000000000000000000000000000000000000005114 157.0
PYH3_k127_4251296_3 - - - - 0.00000000000000000000376 105.0
PYH3_k127_4280847_0 Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol, an intermediate step in ubiquinone biosynthesis K03182 - 4.1.1.98 6.263e-270 847.0
PYH3_k127_4280847_1 Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000004774 228.0
PYH3_k127_4280847_2 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.00000000000000000000000000000000000007957 144.0
PYH3_k127_4313901_0 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 320.0
PYH3_k127_4313901_1 DNA polymerase III, epsilon subunit K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005378 320.0
PYH3_k127_4316530_0 Peptidoglycan polymerase that is essential for cell division K03588 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002412 508.0
PYH3_k127_4316530_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000001151 108.0
PYH3_k127_4316530_2 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000009978 77.0
PYH3_k127_432117_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 594.0
PYH3_k127_432117_1 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000001096 137.0
PYH3_k127_4332408_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 3.297e-230 726.0
PYH3_k127_4332408_1 Belongs to the GARS family K01945 - 6.3.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001907 529.0
PYH3_k127_4332408_2 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000003372 134.0
PYH3_k127_4332408_3 Belongs to the transcriptional regulatory Fis family K03557 - - 0.000000000000000000005924 100.0
PYH3_k127_434013_0 PQQ enzyme repeat - - - 4.404e-303 937.0
PYH3_k127_434013_1 TonB-dependent Receptor Plug Domain K02014 - - 9.356e-216 691.0
PYH3_k127_434013_10 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003031 293.0
PYH3_k127_434013_11 hydrolases or acyltransferases (alpha beta hydrolase superfamily) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002382 283.0
PYH3_k127_434013_12 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005594 279.0
PYH3_k127_434013_13 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000366 245.0
PYH3_k127_434013_14 PFAM Ankyrin K06867 - - 0.00000000000000000000000000000000000000000000000000003016 195.0
PYH3_k127_434013_15 Solute carrier family 35 - - - 0.0000000000000000000000000000000000000000000008948 177.0
PYH3_k127_434013_16 Cytochrome B561 K12262 - - 0.0000000000000000000000000000000000000000313 171.0
PYH3_k127_434013_17 cytochrome - - - 0.000001773 55.0
PYH3_k127_434013_2 TonB-dependent receptor K02014 - - 1.691e-202 675.0
PYH3_k127_434013_3 Glucose / Sorbosone dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003049 583.0
PYH3_k127_434013_4 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 452.0
PYH3_k127_434013_5 40-residue YVTN family beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001157 394.0
PYH3_k127_434013_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines. Specifically modifies U20 and U20a in tRNAs K05539 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 390.0
PYH3_k127_434013_7 Lipocalin-like domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006418 367.0
PYH3_k127_434013_8 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001118 324.0
PYH3_k127_434013_9 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002228 322.0
PYH3_k127_4347137_0 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 571.0
PYH3_k127_4347137_1 prepilin-type N-terminal cleavage methylation K02456 - - 0.000000000000000000000000000000000000000000000000000000003271 202.0
PYH3_k127_4347137_2 prepilin-type N-terminal cleavage methylation K02456 - - 0.00000000000000000000000000000000000000000002763 166.0
PYH3_k127_4347137_3 Type II secretory pathway pseudopilin - - - 0.00000000000000000000000000000000000000005165 166.0
PYH3_k127_4359084_0 extracellular solute-binding protein - - - 1.872e-282 897.0
PYH3_k127_4359084_1 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000656 381.0
PYH3_k127_4359084_2 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000006912 59.0
PYH3_k127_4367531_0 AMP-binding enzyme K01895 - 6.2.1.1 8.476e-236 747.0
PYH3_k127_4367531_1 Ammonium Transporter Family K03320,K06580 - - 1.136e-208 654.0
PYH3_k127_4367531_2 protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001804 432.0
PYH3_k127_4367531_3 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005699 273.0
PYH3_k127_4367531_4 Haloacid dehalogenase-like hydrolase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000003601 209.0
PYH3_k127_4367531_6 Tripartite tricarboxylate transporter TctA family K07793 - - 0.000000000000004894 75.0
PYH3_k127_4378624_0 Bacterial protein of unknown function (DUF853) K06915 - - 5.581e-227 712.0
PYH3_k127_4378624_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004099 592.0
PYH3_k127_4378624_10 Histidine kinase K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 376.0
PYH3_k127_4378624_11 PFAM MotA TolQ ExbB proton channel K03562 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001628 334.0
PYH3_k127_4378624_12 Transcriptional regulatory protein, C terminal K07657 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 323.0
PYH3_k127_4378624_13 Plays a role in the regulation of phosphate uptake K02039 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000266 286.0
PYH3_k127_4378624_14 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005071 273.0
PYH3_k127_4378624_15 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000002836 255.0
PYH3_k127_4378624_16 Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group K01159 - 3.1.22.4 0.0000000000000000000000000000000000000000000000000000000000000000001175 246.0
PYH3_k127_4378624_17 TonB C terminal K03646 - - 0.000000000000000000000000000000000000000000000000575 189.0
PYH3_k127_4378624_18 phosphohistidine phosphatase K08296 - - 0.00000000000000000000000000000000000000002874 166.0
PYH3_k127_4378624_19 Acyl-CoA thioesterase K07107 - - 0.000000000000000000000000000001582 137.0
PYH3_k127_4378624_2 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000248 541.0
PYH3_k127_4378624_20 Biopolymer transport protein ExbD TolR K03560 - - 0.0000000000000000000000000003577 128.0
PYH3_k127_4378624_21 Involved in the tonB-independent uptake of proteins K03641 - - 0.000002986 50.0
PYH3_k127_4378624_3 COG0798 Arsenite efflux pump ACR3 and related permeases K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009785 533.0
PYH3_k127_4378624_4 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003216 467.0
PYH3_k127_4378624_5 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002361 435.0
PYH3_k127_4378624_6 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000135 420.0
PYH3_k127_4378624_7 phosphate transport system permease K02038 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000113 415.0
PYH3_k127_4378624_8 transcriptional regulatory protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000587 377.0
PYH3_k127_4378624_9 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001576 374.0
PYH3_k127_4421479_0 Amidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 433.0
PYH3_k127_4421479_1 Aldo/keto reductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005868 314.0
PYH3_k127_4421479_2 ATP ADP translocase K03301 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000045 258.0
PYH3_k127_4424075_0 BT1 family - - - 2.833e-231 729.0
PYH3_k127_4424075_1 Glucose inhibited division protein A - - - 2.053e-218 707.0
PYH3_k127_4424075_10 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000003564 246.0
PYH3_k127_4424075_11 Protein of unknown function (DUF938) - - - 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
PYH3_k127_4424075_12 Domain of unknown function (DUF1993) K09983 - - 0.000000000000000000000000000000000000000000000000000000000000006689 226.0
PYH3_k127_4424075_13 membrane - - - 0.0000000000000000000000000000000000000000000000000000000000005621 215.0
PYH3_k127_4424075_14 FecR protein - - - 0.00000000000000000000000000000000000000000103 171.0
PYH3_k127_4424075_15 Glycine-zipper domain - - - 0.00000000000000000000000000000000000000001785 160.0
PYH3_k127_4424075_16 - - - - 0.000000000000000000001012 99.0
PYH3_k127_4424075_17 Belongs to the pirin family K06911 - - 0.0000000000000000000271 91.0
PYH3_k127_4424075_18 - - - - 0.0000000107 62.0
PYH3_k127_4424075_2 Uncharacterised ArCR, COG2043 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002794 421.0
PYH3_k127_4424075_3 Haemolysin secretion/activation protein ShlB/FhaC/HecB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 397.0
PYH3_k127_4424075_4 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000461 397.0
PYH3_k127_4424075_5 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 359.0
PYH3_k127_4424075_6 Glucose / Sorbosone dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006457 346.0
PYH3_k127_4424075_7 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 330.0
PYH3_k127_4424075_8 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 312.0
PYH3_k127_4424075_9 HAD-hyrolase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003031 280.0
PYH3_k127_4430780_0 Orn/Lys/Arg decarboxylase, C-terminal domain K01583 - 4.1.1.19 0.0 1073.0
PYH3_k127_4430780_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.687e-210 662.0
PYH3_k127_4430780_2 acetylornithine aminotransferase K00821 - 2.6.1.11,2.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005445 457.0
PYH3_k127_4430780_3 Binds directly to 16S ribosomal RNA K02968 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0004857,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008073,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030234,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0042979,GO:0043043,GO:0043086,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044092,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050790,GO:0065003,GO:0065007,GO:0065009,GO:0070181,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:0098772,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001018 74.0
PYH3_k127_44613_0 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004797 541.0
PYH3_k127_44613_1 COG4665 TRAP-type mannitol chloroaromatic compound transport system small permease component - - - 0.0000000000000002396 85.0
PYH3_k127_4539499_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 - 2.7.7.6 0.0 1453.0
PYH3_k127_4545331_0 Secretin and TonB N terminus short domain K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 582.0
PYH3_k127_4545331_1 carbon utilization - - - 0.000000000000000141 83.0
PYH3_k127_4551780_0 COG1529 Aerobic-type carbon monoxide dehydrogenase large subunit CoxL CutL homologs K07303 - 1.3.99.16 1.539e-283 890.0
PYH3_k127_4551780_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003935 432.0
PYH3_k127_4551780_10 - - - - 0.0001975 48.0
PYH3_k127_4551780_2 Thioesterase-like superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 385.0
PYH3_k127_4551780_3 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007872 345.0
PYH3_k127_4551780_4 SnoaL-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 309.0
PYH3_k127_4551780_5 Thiopurine S-methyltransferase (TPMT) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000022 284.0
PYH3_k127_4551780_6 Belongs to the IlvD Edd family K01687 GO:0003674,GO:0003824,GO:0004160,GO:0016829,GO:0016835,GO:0016836 4.2.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001782 283.0
PYH3_k127_4551780_7 BON domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001127 263.0
PYH3_k127_4551780_8 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000003723 229.0
PYH3_k127_4551780_9 Bacterial extracellular solute-binding protein K02020 - - 0.000000000000000000000000000000000000000000000000000000000000005107 226.0
PYH3_k127_4561126_0 Aldo/keto reductase family K05275 - 1.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 325.0
PYH3_k127_4561126_1 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000003333 216.0
PYH3_k127_4561126_2 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000003895 213.0
PYH3_k127_4561126_3 Major Facilitator Superfamily - - - 0.000000000000000000000000000000009148 130.0
PYH3_k127_4561126_4 Gaf domain K01768,K04769 - 4.6.1.1 0.00002966 56.0
PYH3_k127_4568226_0 Belongs to the MurCDEF family K01924 - 6.3.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 587.0
PYH3_k127_4568226_1 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.0000000000000000000000000000000000000000000000000000000001218 207.0
PYH3_k127_4602612_0 Protein of unknown function - - - 2.365e-275 893.0
PYH3_k127_4602612_1 PFAM Nitrilase cyanide hydratase and apolipoprotein N-acyltransferase K01501,K11206 - 3.5.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003136 350.0
PYH3_k127_4602612_2 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000004299 190.0
PYH3_k127_4621116_0 NADH Ubiquinone plastoquinone (Complex I) K12141 - - 3.016e-252 787.0
PYH3_k127_4621116_1 NADH ubiquinone plastoquinone (Complex I) - - - 4.359e-225 713.0
PYH3_k127_4621116_2 PFAM NADH dehydrogenase (ubiquinone) 30 kDa subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001069 468.0
PYH3_k127_4621116_3 NADH dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 448.0
PYH3_k127_4621116_4 hydrogenase 4 membrane K12140 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002717 299.0
PYH3_k127_4633118_0 Cobalamin synthesis protein cobW C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003099 449.0
PYH3_k127_4633118_1 SMART PUA domain containing protein K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000002929 188.0
PYH3_k127_4677605_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 - 6.1.1.6 1.008e-201 655.0
PYH3_k127_4677605_1 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 531.0
PYH3_k127_4677605_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000451 521.0
PYH3_k127_4677605_3 Single-stranded-DNA-specific exonuclease K07462 - - 0.00000000000000000000000000000000000000000000001925 174.0
PYH3_k127_4677605_4 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000007944 180.0
PYH3_k127_4677605_5 Cyclophilin-like K09143 - - 0.00000000000000000000000000001838 132.0
PYH3_k127_4677605_6 KTSC domain - - - 0.0000003248 60.0
PYH3_k127_4677605_7 17 kDa surface antigen - - - 0.0004311 48.0
PYH3_k127_4683988_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 2.223e-198 634.0
PYH3_k127_4688332_0 Glycosyl hydrolase 36 superfamily, catalytic domain K13688,K18786 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.321 0.0 1808.0
PYH3_k127_4688332_1 His Kinase A (phosphoacceptor) domain - - - 0.0002456 48.0
PYH3_k127_46972_0 Belongs to the peptidase M16 family K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001819 469.0
PYH3_k127_46972_1 mechanosensitive ion channel activity K03282 GO:0003674,GO:0005215,GO:0005216,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015075,GO:0015267,GO:0015318,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022838,GO:0022857,GO:0030104,GO:0031224,GO:0031226,GO:0032535,GO:0034220,GO:0042592,GO:0042802,GO:0044425,GO:0044459,GO:0044464,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0071944,GO:0090066 - 0.00000000000000000000000000000000000000001236 159.0
PYH3_k127_46972_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.00000000000000000002897 91.0
PYH3_k127_4722909_0 PFAM type II and III secretion system protein K02453 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 345.0
PYH3_k127_4722909_1 Tetratricopeptide repeat - - - 0.000000001661 67.0
PYH3_k127_4763811_0 NADH flavin oxidoreductase NADH oxidase K09461 - 1.14.13.40 2.946e-314 1007.0
PYH3_k127_4763811_1 Belongs to the IlvD Edd family K01687 - 4.2.1.9 6.29e-264 823.0
PYH3_k127_4763811_10 COG0685 5,10-methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.0000000000000000000000000000000000000000000000002141 187.0
PYH3_k127_4763811_11 Transcriptional regulator - - - 0.000000000000000000000000000000000000000004454 160.0
PYH3_k127_4763811_12 Transcriptional regulator, LysR family - - - 0.000000000000000000000000000000000000001205 151.0
PYH3_k127_4763811_2 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 1.647e-249 782.0
PYH3_k127_4763811_3 AMP-binding enzyme C-terminal domain K08295 - 6.2.1.32 1.798e-238 747.0
PYH3_k127_4763811_4 AMP-binding enzyme K12508 - 6.2.1.34 7.108e-220 702.0
PYH3_k127_4763811_5 Tripartite ATP-independent periplasmic transporter, DctM component - - - 1.739e-197 623.0
PYH3_k127_4763811_6 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 441.0
PYH3_k127_4763811_7 Cobalamin-independent synthase, Catalytic domain K00549 - 2.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005029 359.0
PYH3_k127_4763811_8 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 365.0
PYH3_k127_4763811_9 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000003192 218.0
PYH3_k127_4764964_0 PFAM Cytochrome c oxidase, subunit I K02274 - 1.9.3.1 1.785e-245 769.0
PYH3_k127_4764964_1 Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group K02259 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 388.0
PYH3_k127_4764964_2 cytochrome c oxidase (Subunit II) K02275 - 1.9.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004411 271.0
PYH3_k127_4764964_3 Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group K02257 - 2.5.1.141 0.00000000000000000000000000000000000000000000000000000000000000000000000654 248.0
PYH3_k127_4764964_4 - - - - 0.0000000000004585 70.0
PYH3_k127_4766442_0 Protein of unknown function (DUF3141) - - - 0.0 1037.0
PYH3_k127_4766442_1 sulfite reductase, dissimilatory-type alpha subunit K11180 - 1.8.99.5 1.775e-218 688.0
PYH3_k127_4766442_10 DsrC like protein K11179 - - 0.000000000000000000000000000000000000007896 159.0
PYH3_k127_4766442_11 part of a sulfur-relay system K11179 - - 0.0000000000000000000000000000000004127 144.0
PYH3_k127_4766442_12 Cas6 Crispr - - - 0.000000000000000000000000000004623 130.0
PYH3_k127_4766442_13 - - - - 0.000000000000000000000000006934 110.0
PYH3_k127_4766442_14 - - - - 0.00000000000000000000000003465 123.0
PYH3_k127_4766442_15 - - - - 0.0000000000000000008601 92.0
PYH3_k127_4766442_16 belongs to the aldehyde dehydrogenase family K10217 - 1.2.1.32,1.2.1.85 0.0000000001344 63.0
PYH3_k127_4766442_2 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003642 472.0
PYH3_k127_4766442_3 PFAM phosphate acetyl butaryl transferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 458.0
PYH3_k127_4766442_4 Fumarylacetoacetate (FAA) hydrolase family K02509 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007544 355.0
PYH3_k127_4766442_5 Putative zinc- or iron-chelating domain K06940 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 317.0
PYH3_k127_4766442_6 Taurine catabolism dioxygenase TauD, TfdA family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005398 295.0
PYH3_k127_4766442_7 Nitrite and sulphite reductase 4Fe-4S domain K11181 - 1.8.99.5 0.000000000000000000000000000000000000000000000000000000000000000000002217 264.0
PYH3_k127_4766442_8 - - - - 0.000000000000000000000000000000000000000000000000009887 193.0
PYH3_k127_4766442_9 Sulfurtransferase TusA - - - 0.00000000000000000000000000000000000000000000001975 177.0
PYH3_k127_4770495_0 Serine aminopeptidase, S33 K01259 - 3.4.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003445 324.0
PYH3_k127_4770495_1 [2Fe-2S] binding domain - - - 0.000000000000000000000000000000000000000000000000000001096 196.0
PYH3_k127_4770495_2 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.00000000000000000000000000000000000000000000000004946 185.0
PYH3_k127_4770495_3 Alpha/beta hydrolase family - - - 0.0000000000000000000001944 110.0
PYH3_k127_479107_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1219.0
PYH3_k127_479107_1 iron ion homeostasis - - - 0.0000000000000000000000000000000000000000000000006324 180.0
PYH3_k127_479515_0 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 336.0
PYH3_k127_479515_1 ApaG domain - - - 0.0000000000000000000000000000000000000000000000000000001878 198.0
PYH3_k127_479515_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.00000000000000000000000000001235 123.0
PYH3_k127_479592_0 amino acid - - - 2.559e-281 879.0
PYH3_k127_479592_1 type I secretion membrane fusion protein, HlyD family K11003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 300.0
PYH3_k127_479592_2 Uncharacterized protein conserved in bacteria (DUF2237) K09966 - - 0.00000000000000000000000000000000000000000000000000001616 190.0
PYH3_k127_479592_3 SapC - - - 0.000000000000000000000000000000000000000004171 164.0
PYH3_k127_479592_4 Tetratricopeptide repeat - - - 0.0000003248 52.0
PYH3_k127_4803137_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 8.768e-296 925.0
PYH3_k127_4803137_1 zinc metalloprotease K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003955 482.0
PYH3_k127_4803137_10 Belongs to the skp family K06142 - - 0.0000000000000000000000000000000000000000000000000000004671 198.0
PYH3_k127_4803137_11 methyltransferase K03437 - - 0.00000000000000000000000000001247 124.0
PYH3_k127_4803137_2 Methyl-transferase K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004633 415.0
PYH3_k127_4803137_3 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008439 418.0
PYH3_k127_4803137_4 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 375.0
PYH3_k127_4803137_5 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001625 379.0
PYH3_k127_4803137_6 Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 361.0
PYH3_k127_4803137_7 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002943 274.0
PYH3_k127_4803137_8 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000007271 225.0
PYH3_k127_4803137_9 Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs K02372 - 4.2.1.59 0.0000000000000000000000000000000000000000000000000000000000202 211.0
PYH3_k127_4830639_0 Transporter - - - 4.269e-214 699.0
PYH3_k127_4830639_1 TRAP transporter, solute receptor (TAXI family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003679 304.0
PYH3_k127_4830639_2 N-terminal half of MaoC dehydratase - - - 0.000000000000000000000000000000000000000000000000004688 187.0
PYH3_k127_4830639_3 Passenger-associated-transport-repeat - - - 0.00000000000000000001139 103.0
PYH3_k127_4830639_4 Major facilitator Superfamily - - - 0.000000004954 70.0
PYH3_k127_4864266_0 - - - - 7.606e-234 760.0
PYH3_k127_4864266_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006066 488.0
PYH3_k127_4864266_2 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 385.0
PYH3_k127_4864266_3 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003688 323.0
PYH3_k127_4864266_4 Beta-lactamase K01069 - 3.1.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005641 291.0
PYH3_k127_4864266_5 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001341 282.0
PYH3_k127_4864266_6 PFAM ABC transporter related K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000001875 246.0
PYH3_k127_4864266_7 Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) K00275 - 1.4.3.5 0.000000000000000000000000000000000000000000000003008 182.0
PYH3_k127_4864266_8 MAPEG family - - - 0.000000000000000000000000000000000000000001884 160.0
PYH3_k127_4864266_9 ABC transporter K01995 - - 0.00000000000000000000000000000000000000008242 153.0
PYH3_k127_4887689_0 Fumarate reductase flavoprotein C-term - - - 1.497e-246 775.0
PYH3_k127_4887689_1 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007145 501.0
PYH3_k127_4887689_2 C4-dicarboxylate transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001305 497.0
PYH3_k127_4887689_3 dehydrogenase, E1 component K00161,K21416 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006891 430.0
PYH3_k127_4887689_4 PFAM Transketolase central region K00162,K21417 - 1.2.4.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000152 419.0
PYH3_k127_4887689_5 2Fe-2S iron-sulfur cluster binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001485 338.0
PYH3_k127_4887689_6 ubiE/COQ5 methyltransferase family K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000011 250.0
PYH3_k127_4887689_7 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.000000000000000000000000000000000000001003 153.0
PYH3_k127_4887689_8 Fumarate reductase subunit C - - - 0.00000000000000000000000000001526 132.0
PYH3_k127_4887689_9 Fumarate reductase subunit D - - - 0.000000000000000000000007359 104.0
PYH3_k127_488812_0 FAD binding domain K00480,K22270 - 1.14.13.1,1.14.13.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002874 473.0
PYH3_k127_488812_1 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 463.0
PYH3_k127_488812_2 L-lactate dehydrogenase K00101,K15054 - 1.1.2.3,1.1.99.31 0.00000000003825 64.0
PYH3_k127_488812_3 Amidase K01426 - 3.5.1.4 0.000001727 54.0
PYH3_k127_489118_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 535.0
PYH3_k127_489118_1 Beta-lactamase domain protein K06897 - 2.5.1.105 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002106 497.0
PYH3_k127_489118_2 transport protein CorA K03284 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 419.0
PYH3_k127_489118_3 Aminotransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002496 402.0
PYH3_k127_489118_4 Uracil DNA glycosylase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006197 248.0
PYH3_k127_489118_5 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000001571 234.0
PYH3_k127_489118_6 ubiE/COQ5 methyltransferase family - - - 0.00000000000000000000000000000000000000000000000000000000000003184 243.0
PYH3_k127_489118_7 Belongs to the Nudix hydrolase family. NudJ subfamily - - - 0.000000000000000000000000000000000000000000000000004259 195.0
PYH3_k127_489118_8 Transcriptional regulator - - - 0.000000000000000003852 86.0
PYH3_k127_4926641_0 Predicted methyltransferase regulatory domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005456 415.0
PYH3_k127_4926641_1 COG2931, RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009056 345.0
PYH3_k127_4926641_2 - - - - 0.0000000000000000000000000000000000000000000000000001769 201.0
PYH3_k127_4926928_0 Rod shape-determining protein MreB K03569 - - 3.38e-201 630.0
PYH3_k127_4926928_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000009788 239.0
PYH3_k127_4926928_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000000005928 105.0
PYH3_k127_4926928_3 Involved in formation and maintenance of cell shape K03570 - - 0.0000000000000000696 82.0
PYH3_k127_493030_0 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001522 341.0
PYH3_k127_493030_1 serine threonine protein kinase K08282 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001113 319.0
PYH3_k127_493030_2 TIGRFAM Carbohydrate kinase, thermoresistant glucokinase K00851 - 2.7.1.12 0.0000000000000000000000000000000000001043 156.0
PYH3_k127_493030_3 - - - - 0.00000000000000000000000002344 115.0
PYH3_k127_493779_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1067.0
PYH3_k127_493779_1 Sodium/calcium exchanger protein K07300 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001128 537.0
PYH3_k127_493779_10 - - - - 0.00001893 50.0
PYH3_k127_493779_2 Aminotransferase K00832 - 2.6.1.57 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003944 527.0
PYH3_k127_493779_3 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006308 511.0
PYH3_k127_493779_4 Ethylbenzene dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 447.0
PYH3_k127_493779_5 Formate/nitrite transporter K06212,K21993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001906 405.0
PYH3_k127_493779_6 Alginate export - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003815 378.0
PYH3_k127_493779_7 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104 GO:0000271,GO:0003674,GO:0003824,GO:0004721,GO:0004725,GO:0005975,GO:0005976,GO:0006464,GO:0006470,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009242,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019538,GO:0033692,GO:0034637,GO:0034645,GO:0035335,GO:0036211,GO:0042578,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044262,GO:0044264,GO:0044267,GO:0046377,GO:0071704,GO:0140096,GO:1901135,GO:1901137,GO:1901564,GO:1901576 3.1.3.48 0.0000000000000000000000000000000000000000000000000000000002626 206.0
PYH3_k127_493779_8 ribosomal large subunit export from nucleus - - - 0.00000000000000000000000000000000000000000000000001213 184.0
PYH3_k127_493779_9 Universal stress protein - - - 0.00000000000000000000000002762 114.0
PYH3_k127_4951038_0 Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate K00451 - 1.13.11.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000102 601.0
PYH3_k127_4951038_1 fumarylacetoacetate (FAA) hydrolase K01555 - 3.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005596 522.0
PYH3_k127_4951038_2 domain protein - - - 0.00000000000000000000000000000000000001626 156.0
PYH3_k127_4951038_3 addiction module toxin, RelE StbE family K19157 - - 0.000000000000000443 83.0
PYH3_k127_4974439_0 nitrite reductase [NAD(P)H] activity K00158,K00363,K03809,K05710 - 1.2.3.3,1.6.5.2,1.7.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 448.0
PYH3_k127_4974439_1 Adenylyl- / guanylyl cyclase, catalytic domain - - - 0.00000000000000000000000000000000000000000000000000002339 190.0
PYH3_k127_4974439_2 - - - - 0.0005322 47.0
PYH3_k127_4979203_0 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002193 401.0
PYH3_k127_4979203_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003314 363.0
PYH3_k127_4979802_0 NhaP-type Na H and K H antiporters with a unique C-terminal domain K11105 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000744 596.0
PYH3_k127_4979802_1 MacB-like periplasmic core domain K02004 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008964 559.0
PYH3_k127_4979802_10 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000008188 277.0
PYH3_k127_4979802_11 MgtC family K07507 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001426 257.0
PYH3_k127_4979802_12 Domain of Unknown Function (DUF1080) - - - 0.0000000000000000000000000000000000000000000000000000000000003773 219.0
PYH3_k127_4979802_13 LysR substrate binding domain - - - 0.000000000000000000000000000000000000000000000000000003879 203.0
PYH3_k127_4979802_14 serine protease K07403 - - 0.00000000000000000000000000001376 121.0
PYH3_k127_4979802_15 Belongs to the HpcH HpaI aldolase family K02510 - 4.1.2.52 0.000000000000000000001312 96.0
PYH3_k127_4979802_2 MacB-like periplasmic core domain K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006203 558.0
PYH3_k127_4979802_3 Histidine kinase-like ATPases - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 562.0
PYH3_k127_4979802_4 amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000273 500.0
PYH3_k127_4979802_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004411 467.0
PYH3_k127_4979802_6 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001746 452.0
PYH3_k127_4979802_7 NADPH:quinone reductase activity K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 388.0
PYH3_k127_4979802_8 abc transporter K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005041 351.0
PYH3_k127_4979802_9 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003463 316.0
PYH3_k127_4980811_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1234.0
PYH3_k127_4980811_1 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 3.563e-215 673.0
PYH3_k127_4980811_10 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000195 349.0
PYH3_k127_4980811_11 phytoene K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002424 340.0
PYH3_k127_4980811_12 squalene-associated FAD-dependent desaturase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000399 324.0
PYH3_k127_4980811_13 TIGRFAM phage SPO1 DNA polymerase-related protein K21929 - 3.2.2.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000001603 275.0
PYH3_k127_4980811_14 PFAM Peptidase M22, glycoprotease K14742 - - 0.00000000000000000000000000000000000000000004428 165.0
PYH3_k127_4980811_15 This enzyme acetylates the N-terminal alanine of ribosomal protein S18 K03789 - 2.3.1.128 0.00000000000000000000000000000000000000001381 165.0
PYH3_k127_4980811_16 Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions K03530 - - 0.00000000000000000000000000000005214 126.0
PYH3_k127_4980811_17 - - - - 0.0000000000000008718 79.0
PYH3_k127_4980811_2 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009502 610.0
PYH3_k127_4980811_3 Major Facilitator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000967 514.0
PYH3_k127_4980811_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002066 473.0
PYH3_k127_4980811_5 peptidylprolyl isomerase K03770 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 447.0
PYH3_k127_4980811_6 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002639 419.0
PYH3_k127_4980811_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001242 421.0
PYH3_k127_4980811_8 Phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000019 398.0
PYH3_k127_4980811_9 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004552 401.0
PYH3_k127_4982941_0 TIGRFAM lipoprotein releasing system, transmembrane protein, LolC E family K09808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004355 565.0
PYH3_k127_4982941_1 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000003349 198.0
PYH3_k127_4982941_2 LysE type translocator - - - 0.0000000000000000000000000000000003378 152.0
PYH3_k127_4982941_3 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.000000000000000000000000001254 117.0
PYH3_k127_4990679_0 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 434.0
PYH3_k127_4990679_1 (Lipo)protein K07287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 403.0
PYH3_k127_4990679_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004162 302.0
PYH3_k127_4990679_3 PFAM Methyltransferase type - - - 0.0000000000000000000000000000000000000000000000000001388 197.0
PYH3_k127_4990679_4 - - - - 0.000000000000000001303 94.0
PYH3_k127_4990679_5 Domain of Unknown Function (DUF748) - - - 0.00000000121 64.0
PYH3_k127_4993094_0 5-oxoprolinase K01469,K01473 - 3.5.2.14,3.5.2.9 2.7e-259 808.0
PYH3_k127_4993094_1 AsmA-like C-terminal region - - - 0.0003248 47.0
PYH3_k127_4998846_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 1.075e-241 759.0
PYH3_k127_4998846_1 Belongs to the monovalent cation proton antiporter 2 (cpa2) transporter (TC 2.A.37) family K03455 - - 7.992e-223 709.0
PYH3_k127_4998846_10 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family K03270 - 3.1.3.45 0.0000000000000000000000000000000000000000000000000001885 198.0
PYH3_k127_4998846_11 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000002958 191.0
PYH3_k127_4998846_12 Tetratricopeptide repeats - - - 0.0000000000000000000000000000000000000000000004655 173.0
PYH3_k127_4998846_13 general secretion pathway protein - - - 0.000000000000000000000000000000001723 148.0
PYH3_k127_4998846_14 Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane K09774 - - 0.0000000000000000000000000000003514 137.0
PYH3_k127_4998846_15 Lipopolysaccharide-assembly, LptC-related K11719 - - 0.00000000000000000000000004923 121.0
PYH3_k127_4998846_16 - - - - 0.0000000000000000000000005374 114.0
PYH3_k127_4998846_17 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000009898 83.0
PYH3_k127_4998846_18 - - - - 0.000000000000003999 82.0
PYH3_k127_4998846_2 type II secretion system protein K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001426 492.0
PYH3_k127_4998846_3 Histidine kinase-like ATPases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 451.0
PYH3_k127_4998846_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003946 414.0
PYH3_k127_4998846_5 ABC-type (Unclassified) transport system, ATPase component K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001741 367.0
PYH3_k127_4998846_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002835 257.0
PYH3_k127_4998846_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000004552 236.0
PYH3_k127_4998846_9 Prokaryotic N-terminal methylation motif - - - 0.000000000000000000000000000000000000000000000000000002739 198.0
PYH3_k127_5039954_0 Methyl-accepting chemotaxis protein K02660 - - 5.694e-222 710.0
PYH3_k127_5039954_1 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000000000000001113 222.0
PYH3_k127_5039954_2 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000000000000000000003495 222.0
PYH3_k127_5039954_3 response regulator receiver K02658 - - 0.00000000000000000000000000000000000000000000004522 181.0
PYH3_k127_5039954_4 Chemotaxis signal transduction protein K02659 - - 0.00000000000000000000000000000000000004709 150.0
PYH3_k127_5039954_5 Rubredoxin - - - 0.0000000000000000000000000000005591 123.0
PYH3_k127_5039954_6 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.000000000000000000000000000001079 126.0
PYH3_k127_5054488_0 N-Acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 488.0
PYH3_k127_5054488_1 PFAM SNARE associated Golgi protein K03975 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000115 253.0
PYH3_k127_5054488_2 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 - - 0.0000000000000000000000000000000000001197 145.0
PYH3_k127_5070411_0 GMC oxidoreductase K00108 - 1.1.99.1 2.983e-241 754.0
PYH3_k127_5070411_1 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 3.683e-205 677.0
PYH3_k127_5070411_10 Oxidative deamination of D-amino acids K00285 - 1.4.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009966 535.0
PYH3_k127_5070411_11 beta-keto acid cleavage enzyme - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008427 465.0
PYH3_k127_5070411_12 CHASE2 K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 454.0
PYH3_k127_5070411_13 Belongs to the TPP enzyme family K03852 - 2.3.3.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000616 378.0
PYH3_k127_5070411_14 belongs to the CobB CobQ family K13788 - 2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 310.0
PYH3_k127_5070411_15 NADP oxidoreductase, coenzyme f420-dependent K06988 - 1.5.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 285.0
PYH3_k127_5070411_16 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000156 270.0
PYH3_k127_5070411_17 Glutathione S-transferase, N-terminal domain K00799 - 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000007562 228.0
PYH3_k127_5070411_18 COG4665 TRAP-type mannitol chloroaromatic compound transport system, small permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000004004 224.0
PYH3_k127_5070411_19 Universal stress protein family - - - 0.000000000000000000000000000000000000169 152.0
PYH3_k127_5070411_2 TRAP-type mannitol chloroaromatic compound transport system large permease component - - - 1.749e-203 650.0
PYH3_k127_5070411_21 - - - - 0.0000004605 59.0
PYH3_k127_5070411_22 short-chain dehydrogenase - - - 0.00001061 54.0
PYH3_k127_5070411_3 Adenylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 618.0
PYH3_k127_5070411_4 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 608.0
PYH3_k127_5070411_5 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001776 616.0
PYH3_k127_5070411_6 3-hydroxyacyl-CoA dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009487 584.0
PYH3_k127_5070411_7 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 570.0
PYH3_k127_5070411_8 Na+-transporting oxaloacetate decarboxylase beta subunit K01572 - 4.1.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001123 572.0
PYH3_k127_5070411_9 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003075 565.0
PYH3_k127_5080452_0 Branched-chain amino acid transport system / permease component K11961 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001645 537.0
PYH3_k127_5080452_1 Belongs to the binding-protein-dependent transport system permease family K11960 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 492.0
PYH3_k127_5080452_2 Branched-chain amino acid ATP-binding cassette transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004752 408.0
PYH3_k127_5080452_3 ABC transporter, ATP-binding protein K11963 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 377.0
PYH3_k127_5080452_4 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.0000000000000000000004531 98.0
PYH3_k127_5081137_0 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 612.0
PYH3_k127_5081137_1 Belongs to the RNA methyltransferase TrmD family K00554 GO:0000287,GO:0001510,GO:0002939,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042802,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046872,GO:0050518,GO:0052906,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 323.0
PYH3_k127_5081137_2 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 - - 0.000000000000000000000000000000000000000000000000000006244 199.0
PYH3_k127_5081137_3 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.00000000000000000000000000000000001009 141.0
PYH3_k127_5081137_4 KR domain - - - 0.0000000000000000000000000000000007533 142.0
PYH3_k127_5081137_5 Belongs to the bacterial ribosomal protein bS16 family K02959 - - 0.00000000000000000000000000003067 119.0
PYH3_k127_5081137_6 - - - - 0.000000000000129 73.0
PYH3_k127_5081137_7 PFAM Cytochrome c assembly protein - - - 0.0007843 43.0
PYH3_k127_508686_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001116 509.0
PYH3_k127_508686_1 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 370.0
PYH3_k127_508686_2 Transfers the fatty acyl group on membrane lipoproteins K03820 - - 0.00000000000000000000000000000000001195 138.0
PYH3_k127_5096574_0 Outer membrane protein transport protein (OMPP1/FadL/TodX) K06076 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000232 336.0
PYH3_k127_5096574_1 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005699 269.0
PYH3_k127_5096574_2 CHAD - - - 0.0000000000000000000000000000000000000000000000000000000000001328 224.0
PYH3_k127_5096574_3 Belongs to the sulfur carrier protein TusA family K04085 - - 0.000000000000000000000000000005737 121.0
PYH3_k127_5112438_0 VanZ like family - - - 0.0000000000000000000000000000000000000000000000008771 182.0
PYH3_k127_5112438_1 Ferredoxin - - - 0.0000000000000000000000000000000000000000000003933 168.0
PYH3_k127_5112438_2 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000000000000000000000000000000000007463 173.0
PYH3_k127_5117009_0 Together with LptE, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007444 565.0
PYH3_k127_5117009_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000152 75.0
PYH3_k127_5122815_0 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 1.521e-255 799.0
PYH3_k127_5122815_1 Indolepyruvate ferredoxin oxidoreductase K00179 - 1.2.7.8 0.00000000000000000003248 90.0
PYH3_k127_5129610_0 Metallopeptidase family M24 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 610.0
PYH3_k127_5129610_1 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 504.0
PYH3_k127_5129610_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007671 371.0
PYH3_k127_5129610_3 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001036 291.0
PYH3_k127_5129610_4 Alcohol dehydrogenase GroES-like domain K00001,K00055 - 1.1.1.1,1.1.1.90 0.00000000000000000003417 98.0
PYH3_k127_5129610_5 cytochrome - - - 0.000000000000006327 82.0
PYH3_k127_5129610_6 - - - - 0.0003577 53.0
PYH3_k127_513632_0 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003211 370.0
PYH3_k127_513632_1 Cytochrome c3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000008139 262.0
PYH3_k127_513632_2 Transcriptional regulator, Crp Fnr family K21563 - - 0.0000000000000732 81.0
PYH3_k127_513632_3 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000002652 59.0
PYH3_k127_5141909_0 Belongs to the cysteine synthase cystathionine beta- synthase family K12339 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 488.0
PYH3_k127_5141909_1 Catalyzes the interconversion between ADP-D-glycero- beta-D-manno-heptose and ADP-L-glycero-beta-D-manno-heptose via an epimerization at carbon 6 of the heptose K03274 - 5.1.3.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002051 420.0
PYH3_k127_5141909_2 Predicted 3'-5' exonuclease related to the exonuclease domain of PolB K07501 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006559 349.0
PYH3_k127_5141909_3 pfkB family carbohydrate kinase K03272,K21344 - 2.7.1.167,2.7.7.70 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004828 302.0
PYH3_k127_5141909_4 Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0070041,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.0000002242 56.0
PYH3_k127_5148631_0 - - - - 0.0 1306.0
PYH3_k127_5148631_1 hydrolase activity, acting on ester bonds K01563 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 465.0
PYH3_k127_5148631_10 cytochrome c5 - - - 0.00000000000000000000000000000000000000000001401 171.0
PYH3_k127_5148631_11 Histidine kinase K08082 - 2.7.13.3 0.00008702 45.0
PYH3_k127_5148631_2 Dienelactone hydrolase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005019 370.0
PYH3_k127_5148631_3 cAMP biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004617 348.0
PYH3_k127_5148631_4 Transmembrane secretion effector - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008603 338.0
PYH3_k127_5148631_5 Serine aminopeptidase, S33 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001655 292.0
PYH3_k127_5148631_6 Protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005097 292.0
PYH3_k127_5148631_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000719 224.0
PYH3_k127_5148631_8 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.00000000000000000000000000000000000000000000002138 181.0
PYH3_k127_5148631_9 chromosome segregation K03497 - - 0.00000000000000000000000000000000000000000000002373 181.0
PYH3_k127_515298_0 AAA domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000358 571.0
PYH3_k127_515298_1 Universal stress protein family - - - 0.00000000000001168 87.0
PYH3_k127_5165747_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002811 445.0
PYH3_k127_5165747_1 D-alanyl-D-alanine carboxypeptidase K07259 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004261 300.0
PYH3_k127_5165747_2 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.00000000000000000000000000000000000000000000004653 171.0
PYH3_k127_5165747_3 PFAM Polysaccharide deacetylase - - - 0.0005536 46.0
PYH3_k127_5234875_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 5e-324 998.0
PYH3_k127_5234875_1 PFAM carboxyl transferase K01615 - 4.1.1.70 8.742e-296 917.0
PYH3_k127_5234875_2 PFAM Acyl-CoA dehydrogenase K16173 - 1.3.99.32 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004652 554.0
PYH3_k127_5234875_3 Uncharacterized ACR, COG1678 - - - 0.0000000000000000000000001891 114.0
PYH3_k127_5234875_4 Universal stress protein - - - 0.0000000000000000000001261 102.0
PYH3_k127_5234875_5 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000001363 105.0
PYH3_k127_5234875_6 Biotin-requiring enzyme - - - 0.0000000000000007623 86.0
PYH3_k127_5248054_0 Allophanate hydrolase K01457 - 3.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001325 587.0
PYH3_k127_5248054_1 Membrane protein FdrA - - - 0.00000000000002181 80.0
PYH3_k127_5300307_0 Belongs to the ABC transporter superfamily K02010 - 3.6.3.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001637 524.0
PYH3_k127_5300307_1 Binding-protein-dependent transport system inner membrane component K02011 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000812 385.0
PYH3_k127_5300307_2 Gram-negative bacterial TonB protein C-terminal K03832 - - 0.00000000000001215 78.0
PYH3_k127_5307192_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1138.0
PYH3_k127_5307192_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006254 471.0
PYH3_k127_5307192_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003387 355.0
PYH3_k127_5307192_3 Protein of unknown function (DUF4197) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000006857 261.0
PYH3_k127_5307192_4 Belongs to the pseudomonas-type ThrB family K02204 - 2.7.1.39 0.00000000000000000000000000000000000000000000000000000002057 203.0
PYH3_k127_5307192_5 Protein of unknown function (DUF2782) - - - 0.00000000000000000000004527 104.0
PYH3_k127_5307192_6 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.0000000000000000000001176 98.0
PYH3_k127_5308564_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain - - - 0.0 1192.0
PYH3_k127_5308564_1 Belongs to the binding-protein-dependent transport system permease family K01997,K01998 - - 4.491e-251 790.0
PYH3_k127_5308564_2 COG1180 Pyruvate-formate lyase-activating enzyme - - - 5.033e-233 728.0
PYH3_k127_5308564_3 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002818 571.0
PYH3_k127_5308564_4 Isochorismatase family K08281 - 3.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 347.0
PYH3_k127_5308564_5 CO dehydrogenase flavoprotein C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004342 306.0
PYH3_k127_5308564_6 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002777 287.0
PYH3_k127_5308564_7 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.000000000000000000000000000000000000000000000000000002945 216.0
PYH3_k127_5308564_8 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.00000000000000000000000000000000000003008 145.0
PYH3_k127_5362271_0 Enoyl- acyl-carrier-protein reductase NADH K00208 - 1.3.1.10,1.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000702 411.0
PYH3_k127_5362271_1 TIGRFAM 3-hydroxybutyrate dehydrogenase K00019 - 1.1.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003716 376.0
PYH3_k127_5362271_10 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 0.0000000007974 59.0
PYH3_k127_5362271_2 Coenzyme A transferase K01029,K01035 - 2.8.3.5,2.8.3.8,2.8.3.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004506 342.0
PYH3_k127_5362271_3 TIGRFAM 3-oxoacid CoA-transferase, A subunit K01034 - 2.8.3.8,2.8.3.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 329.0
PYH3_k127_5362271_4 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995,K08744 - 2.7.8.41,2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 265.0
PYH3_k127_5362271_5 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000002835 266.0
PYH3_k127_5362271_6 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000007561 197.0
PYH3_k127_5362271_7 OmpA family - - - 0.000000000000000000000000000000000000000008129 160.0
PYH3_k127_5362271_8 FecR protein - - - 0.000000000000000000000000000000000000002213 151.0
PYH3_k127_5362271_9 Histidine kinase-like ATPase domain - - - 0.000000000000000009214 92.0
PYH3_k127_536935_0 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000004355 226.0
PYH3_k127_536935_1 PFAM Sporulation domain protein - - - 0.000000000000000000000000004075 116.0
PYH3_k127_536935_2 Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon K03524 GO:0000166,GO:0000976,GO:0000984,GO:0001017,GO:0001067,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003824,GO:0004077,GO:0005488,GO:0005515,GO:0005524,GO:0005575,GO:0006082,GO:0006464,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009305,GO:0009374,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0017053,GO:0017076,GO:0017144,GO:0018130,GO:0018271,GO:0019538,GO:0019752,GO:0019842,GO:0030554,GO:0031406,GO:0032553,GO:0032555,GO:0032559,GO:0032787,GO:0032991,GO:0033218,GO:0033293,GO:0034641,GO:0035639,GO:0036094,GO:0036211,GO:0042364,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043565,GO:0043603,GO:0043604,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901681,GO:1990837 6.3.4.15 0.00001088 51.0
PYH3_k127_538131_0 Dehydratase family K13875 - 4.2.1.25 8.794e-305 943.0
PYH3_k127_538131_1 RuBisCO catalyzes two reactions the carboxylation of D- ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site K01601 - 4.1.1.39 1.814e-283 874.0
PYH3_k127_538131_10 Belongs to the ABC transporter superfamily K10112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005472 487.0
PYH3_k127_538131_11 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007834 436.0
PYH3_k127_538131_12 PFAM fumarylacetoacetate (FAA) hydrolase K18336 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002866 417.0
PYH3_k127_538131_13 Enoyl-(Acyl carrier protein) reductase K21883 - 1.1.1.401 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008501 324.0
PYH3_k127_538131_14 Enoyl-(Acyl carrier protein) reductase K00019,K18335 - 1.1.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 334.0
PYH3_k127_538131_15 Redoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003669 299.0
PYH3_k127_538131_16 NADH pyrophosphatase-like rudimentary NUDIX domain K03426 - 3.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 305.0
PYH3_k127_538131_17 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001641 284.0
PYH3_k127_538131_18 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000005594 227.0
PYH3_k127_538131_19 Tripartite ATP-independent periplasmic transporter - - - 0.0000000000000000000000000000000000000000000000000000000000001074 220.0
PYH3_k127_538131_2 D-galactarate dehydratase / Altronate hydrolase, C terminus K01685 - 4.2.1.7 1.218e-228 717.0
PYH3_k127_538131_20 PFAM Ribulose bisphosphate carboxylase, small chain K01602 - 4.1.1.39 0.0000000000000000000000000000000000000005412 156.0
PYH3_k127_538131_21 AraC-like ligand binding domain - - - 0.000000000000000000000000000000002562 141.0
PYH3_k127_538131_22 subfamily IA, variant 3 - - - 0.000000000000000000000000000002824 123.0
PYH3_k127_538131_23 protein ubiquitination - - - 0.00002201 54.0
PYH3_k127_538131_3 Bacterial extracellular solute-binding protein K02027 - - 5.248e-214 672.0
PYH3_k127_538131_4 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00822 - 2.6.1.18 2.44e-198 631.0
PYH3_k127_538131_5 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000035 601.0
PYH3_k127_538131_6 Binding-protein-dependent transport system inner membrane component K02025,K10237 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001627 518.0
PYH3_k127_538131_7 TIGRFAM amidase, hydantoinase carbamoylase family K06016 - 3.5.1.6,3.5.1.87 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 525.0
PYH3_k127_538131_8 Belongs to the PdxA family K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 494.0
PYH3_k127_538131_9 ABC-type sugar transport system, permease component K02026 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 497.0
PYH3_k127_541138_0 xanthine dehydrogenase activity K04108 - 1.3.7.9 3.685e-263 841.0
PYH3_k127_541138_1 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001108 359.0
PYH3_k127_541138_2 xanthine dehydrogenase activity K04109 - 1.3.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005563 330.0
PYH3_k127_541138_3 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000001739 217.0
PYH3_k127_541138_4 Glycine cleavage system T protein K00605 - 2.1.2.10 0.000000000000000000006967 107.0
PYH3_k127_541138_5 Sir2 family K12410 - - 0.0000000000002875 71.0
PYH3_k127_544516_0 3-hydroxyacyl-CoA dehydrogenase, NAD binding domain K01782 - 1.1.1.35,4.2.1.17,5.1.2.3 1.003e-283 907.0
PYH3_k127_544516_1 Belongs to the thiolase family K00626 - 2.3.1.9 1.61e-197 621.0
PYH3_k127_544516_2 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000116 557.0
PYH3_k127_544516_3 Conserved hypothetical protein 698 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 534.0
PYH3_k127_544516_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001594 452.0
PYH3_k127_544516_5 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.000000000000059 84.0
PYH3_k127_548863_0 catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-acp K00646,K09458 GO:0003674,GO:0003824,GO:0004312,GO:0004315,GO:0016740,GO:0016746,GO:0016747,GO:0033817 2.3.1.179 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 369.0
PYH3_k127_548863_1 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000267 338.0
PYH3_k127_548863_2 Malonyl CoA-acyl carrier protein transacylase K00645,K15355 GO:0003674,GO:0003824,GO:0004312,GO:0004314,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016053,GO:0016417,GO:0016419,GO:0016420,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0071704,GO:0072330,GO:1901576 2.3.1.39 0.0000000000000000000000000000000000000001091 153.0
PYH3_k127_548863_3 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000000000002206 134.0
PYH3_k127_5490439_0 Belongs to the argininosuccinate synthase family. Type 2 subfamily K01940 - 6.3.4.5 2.399e-209 672.0
PYH3_k127_5490439_1 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 511.0
PYH3_k127_5490439_2 general L-amino acid-binding periplasmic protein AapJ K09969 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009733 497.0
PYH3_k127_5490439_3 COG0765 ABC-type amino acid transport system, permease component K09971 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003806 447.0
PYH3_k127_5490439_4 PFAM Glutamine amidotransferase class-I K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000067 324.0
PYH3_k127_5490439_5 protein-L-isoaspartate O-methyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000000000000004857 254.0
PYH3_k127_5490439_6 gag-polyprotein putative aspartyl protease K06985 - - 0.000000000000000000000000000000000000000000000000000000001184 207.0
PYH3_k127_5490439_7 PFAM Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 0.000000000000000006146 85.0
PYH3_k127_5516708_0 Oxidoreductase - - - 1.558e-201 647.0
PYH3_k127_5516708_1 PFAM Extracellular ligand-binding receptor K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 504.0
PYH3_k127_5516708_2 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.000000000000000000000000000000000000000000000000001837 191.0
PYH3_k127_5516708_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000009403 170.0
PYH3_k127_5516708_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000004828 136.0
PYH3_k127_5516708_5 Copper binding periplasmic protein CusF - - - 0.00000000000000000000000000001349 119.0
PYH3_k127_5522748_0 Belongs to the glutamate synthase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007488 576.0
PYH3_k127_5522748_1 PFAM AMP-dependent synthetase and ligase K01895 - 6.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 508.0
PYH3_k127_5534959_0 Flavin-binding monooxygenase-like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001403 533.0
PYH3_k127_5534959_1 glycolate oxidase subunit GlcD - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002636 511.0
PYH3_k127_5534959_2 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006058 318.0
PYH3_k127_5534959_3 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 317.0
PYH3_k127_5534959_4 Vitamin k epoxide reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007304 290.0
PYH3_k127_5534959_5 Receptor family ligand binding region K01999 - - 0.0000000000000000000000000000000000001018 158.0
PYH3_k127_5534959_6 Iron-sulfur cluster assembly protein - - - 0.000000000000000000000000004171 115.0
PYH3_k127_5534959_7 acetyltransferases and hydrolases with the alpha beta hydrolase fold - - - 0.00000000002008 76.0
PYH3_k127_5534959_8 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.0009222 42.0
PYH3_k127_5568418_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 5.733e-261 815.0
PYH3_k127_5568418_1 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 4.531e-207 650.0
PYH3_k127_5568418_10 Alpha/beta hydrolase family - - - 0.00000000000002013 76.0
PYH3_k127_5568418_2 Zinc-binding dehydrogenase K12957,K13953,K19961 - 1.1.1.1,1.1.1.258 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 421.0
PYH3_k127_5568418_3 alpha/beta hydrolase fold K01066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002946 339.0
PYH3_k127_5568418_4 zinc protease protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000121 291.0
PYH3_k127_5568418_5 B-1 B cell differentiation K03634,K14166 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003048 300.0
PYH3_k127_5568418_6 Glutathione S-Transferase K00799 GO:0003674,GO:0003824,GO:0004364,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0016491,GO:0016740,GO:0016765,GO:0030611,GO:0042802,GO:0044424,GO:0044444,GO:0044464,GO:0055114 2.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000001068 269.0
PYH3_k127_5568418_7 CoA-binding protein K06929 - - 0.00000000000000000000000000000000000000000000000000000000000000000197 229.0
PYH3_k127_5568418_8 helix_turn_helix, arabinose operon control protein - - - 0.00000000000000000000000000000000000000000007683 171.0
PYH3_k127_5568418_9 NIPSNAP - - - 0.000000000000000000000000000000000000000004253 157.0
PYH3_k127_5612998_0 Peptidase M50 K16922 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001549 578.0
PYH3_k127_5612998_1 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 352.0
PYH3_k127_5620370_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 2.003e-241 754.0
PYH3_k127_5620370_1 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 3.986e-227 709.0
PYH3_k127_5620370_10 pyruvate flavodoxin ferredoxin oxidoreductase K00169,K03737 - 1.2.7.1 0.000000000000000000000004499 104.0
PYH3_k127_5620370_11 pilus assembly protein FimV K08086 - - 0.0000000000000000000000168 108.0
PYH3_k127_5620370_2 Catalyzes the formation of L-homocysteine from O- succinyl-L-homoserine (OSHS) and hydrogen sulfide K01739,K10764 - 2.5.1.48 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006468 548.0
PYH3_k127_5620370_3 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 459.0
PYH3_k127_5620370_4 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001708 447.0
PYH3_k127_5620370_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003539 365.0
PYH3_k127_5620370_6 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 - 5.4.99.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 343.0
PYH3_k127_5620370_7 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000008457 254.0
PYH3_k127_5620370_8 PFAM Colicin V production protein K03558 - - 0.00000000000000000000000000000000007792 145.0
PYH3_k127_5620370_9 Sporulation related domain K03749 - - 0.00000000000000000000000002869 115.0
PYH3_k127_5638616_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1495.0
PYH3_k127_5638616_1 chain 5 L K00341 - 1.6.5.3 1.14e-278 869.0
PYH3_k127_5638616_10 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000001942 205.0
PYH3_k127_5638616_11 response to abiotic stimulus K06867 - - 0.0000000000000000000000000000000000000000000000002565 186.0
PYH3_k127_5638616_12 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000009982 169.0
PYH3_k127_5638616_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreB releases sequences of up to 9 nucleotides in length K04760 - - 0.0000000000000000000000000000000000009994 144.0
PYH3_k127_5638616_14 Molybdopterin oxidoreductase Fe4S4 domain K00336 - 1.6.5.3 0.000000000006664 68.0
PYH3_k127_5638616_2 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 1.364e-247 771.0
PYH3_k127_5638616_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002544 569.0
PYH3_k127_5638616_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 527.0
PYH3_k127_5638616_5 PFAM Metal-dependent phosphohydrolase, HD - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004934 299.0
PYH3_k127_5638616_6 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002071 290.0
PYH3_k127_5638616_7 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000006731 262.0
PYH3_k127_5638616_8 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002192 274.0
PYH3_k127_5638616_9 Carboxymuconolactone decarboxylase family - - - 0.0000000000000000000000000000000000000000000000000000000003262 207.0
PYH3_k127_5674251_0 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001889 384.0
PYH3_k127_5674251_1 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000002555 222.0
PYH3_k127_5674251_2 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.0000000000000008557 78.0
PYH3_k127_5677424_0 Type II secretion system (T2SS), protein E, N-terminal domain K02454 - - 3.015e-289 898.0
PYH3_k127_5677424_1 Major facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001298 547.0
PYH3_k127_5677424_2 Diguanylate cyclase phosphodiesterase with PAS PAC - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 455.0
PYH3_k127_5682839_0 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 6.409e-265 898.0
PYH3_k127_5682839_1 PFAM AMP-dependent synthetase and ligase K20034 - 6.2.1.44 2.551e-258 805.0
PYH3_k127_5682839_10 ATPases associated with a variety of cellular activities K01995 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 367.0
PYH3_k127_5682839_11 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001976 350.0
PYH3_k127_5682839_12 Alpha/beta hydrolase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003758 284.0
PYH3_k127_5682839_13 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009836 269.0
PYH3_k127_5682839_14 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000006868 267.0
PYH3_k127_5682839_15 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000000000000000004575 210.0
PYH3_k127_5682839_16 Cell wall hydrolase autolysin K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000001184 207.0
PYH3_k127_5682839_17 dehydratase - - - 0.000000000000000000000000000000000000000000000000004008 185.0
PYH3_k127_5682839_18 L-2-amino-thiazoline-4-carboxylic acid hydrolase - - - 0.0000000000000000000000000000000000000000001302 176.0
PYH3_k127_5682839_19 phosphorelay signal transduction system K11443 - - 0.000000000000000000000000000000000318 148.0
PYH3_k127_5682839_2 Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate - - - 9.262e-212 669.0
PYH3_k127_5682839_3 Receptor family ligand binding region - - - 3.226e-208 662.0
PYH3_k127_5682839_4 Putative cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001556 480.0
PYH3_k127_5682839_5 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001126 437.0
PYH3_k127_5682839_6 Periplasmic binding protein domain K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 431.0
PYH3_k127_5682839_7 Branched-chain amino acid transport system / permease component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004521 420.0
PYH3_k127_5682839_8 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001782 422.0
PYH3_k127_5682839_9 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 437.0
PYH3_k127_5686307_0 Protein of unknown function (DUF2721) - - - 0.000000000000000000001184 108.0
PYH3_k127_5686307_1 Domain of unknown function (DUF4340) - - - 0.0000000000000007083 89.0
PYH3_k127_5686307_2 hydrolase activity, acting on ester bonds - - - 0.0000002456 62.0
PYH3_k127_5690389_0 TIGRFAM Acetolactate synthase, large subunit, biosynthetic K01652 - 2.2.1.6 2.451e-308 954.0
PYH3_k127_5690389_1 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 570.0
PYH3_k127_5690389_2 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002606 257.0
PYH3_k127_5690389_3 Acetolactate synthase small K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000002921 257.0
PYH3_k127_5690389_4 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.000000000000000000000000000003395 121.0
PYH3_k127_5750293_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003677 601.0
PYH3_k127_5750293_1 XdhC and CoxI family K07402 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003855 423.0
PYH3_k127_5750293_2 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.000000000000000000000000000000000000000000000000000000005359 203.0
PYH3_k127_5750293_3 Molybdopterin-guanine dinucleotide biosynthesis protein MobA K07141 - 2.7.7.76 0.000000000000000000000000000000000000000000000000004741 192.0
PYH3_k127_5750293_4 Two-component sensor kinase N-terminal - - - 0.000000000000000000000000000000000000000007532 161.0
PYH3_k127_5750293_5 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.00000000000000000000000000007437 124.0
PYH3_k127_5750293_6 Catalyzes the reversible phosphorylation of UMP to UDP K09903 GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015949,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.4.22 0.000000000000002746 83.0
PYH3_k127_5774358_0 ABC-type uncharacterized transport system - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001864 365.0
PYH3_k127_578758_0 NADH flavin oxidoreductase NADH oxidase K00219 - 1.3.1.34 1.451e-241 764.0
PYH3_k127_578758_1 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 2.321e-241 758.0
PYH3_k127_578758_10 Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein K03611 - - 0.0000000007993 60.0
PYH3_k127_578758_2 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 4.093e-211 663.0
PYH3_k127_578758_3 Belongs to the enoyl-CoA hydratase isomerase family K01692,K01715 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001396 397.0
PYH3_k127_578758_4 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005615 329.0
PYH3_k127_578758_5 Phenylacetic acid degradation protein PaaY K08279 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002383 273.0
PYH3_k127_578758_6 Metal binding domain of Ada K00567,K10778 - 2.1.1.63 0.000000000000000000000000000000000000000000000000000000000000000000002185 261.0
PYH3_k127_578758_7 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000005455 246.0
PYH3_k127_578758_8 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000002484 229.0
PYH3_k127_578758_9 PFAM isochorismatase hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000001144 211.0
PYH3_k127_5803635_0 Lactonase, 7-bladed beta-propeller - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002937 523.0
PYH3_k127_5803635_1 Na( ) H( ) antiporter that extrudes sodium in exchange for external protons K03313 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009912 432.0
PYH3_k127_5803635_10 COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) K00046 - 1.1.1.69 0.00000000000000000000000000000006756 137.0
PYH3_k127_5803635_11 Domain of unknown function (DUF1330) - - - 0.00000000000000000000000008331 113.0
PYH3_k127_5803635_12 cellulose binding K01183,K01233,K13381 GO:0003674,GO:0003824,GO:0004553,GO:0004568,GO:0005575,GO:0005623,GO:0008843,GO:0016787,GO:0016798,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464 3.2.1.132,3.2.1.14,3.2.1.17 0.0000000000000000000000001453 114.0
PYH3_k127_5803635_14 PFAM Carboxymuconolactone decarboxylase - - - 0.000799 49.0
PYH3_k127_5803635_2 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002889 320.0
PYH3_k127_5803635_3 phosphoserine phosphatase homoserine phosphotransferase bifunctional protein K02203 - 2.7.1.39,3.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003849 282.0
PYH3_k127_5803635_4 Thioesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000003941 243.0
PYH3_k127_5803635_5 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000000000000000005844 194.0
PYH3_k127_5803635_6 Flavin reductase like domain - - - 0.00000000000000000000000000000000000000169 154.0
PYH3_k127_5803635_7 Chromate transporter K07240 - - 0.000000000000000000000000000000000000004817 164.0
PYH3_k127_5803635_8 overlaps another CDS with the same product name K07240 - - 0.0000000000000000000000000000000000001933 147.0
PYH3_k127_5803635_9 PFAM cytoplasmic chaperone TorD family protein - - - 0.00000000000000000000000000000000009136 140.0
PYH3_k127_5813084_0 tRNA synthetases class I (E and Q), anti-codon binding domain K01886 - 6.1.1.18 5.439e-266 828.0
PYH3_k127_5813084_1 Amidohydrolase family - - - 2.977e-205 651.0
PYH3_k127_5813084_2 Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily K00001,K00344 - 1.1.1.1,1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003395 413.0
PYH3_k127_5813084_3 COG0834 ABC-type amino acid transport signal transduction systems periplasmic component domain K02030 - - 0.0000000000000000000000000000000000000000000000000000000000006757 215.0
PYH3_k127_5834975_0 Acyl-CoA dehydrogenase N terminal K20035 - - 3.109e-246 788.0
PYH3_k127_5834975_1 AMP-binding enzyme C-terminal domain K00666 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 601.0
PYH3_k127_5834975_2 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005753 556.0
PYH3_k127_5834975_3 Electron transfer flavoprotein, alpha subunit K03522 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009347 453.0
PYH3_k127_5834975_4 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005525 456.0
PYH3_k127_5834975_5 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005793 355.0
PYH3_k127_5834975_6 2-oxoacid acceptor oxidoreductase, gamma subunit, pyruvate 2-ketoisovalerate K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000008499 175.0
PYH3_k127_584032_0 PFAM Hemerythrin HHE cation binding domain - - - 0.0000000000000000000000000000000000000000702 160.0
PYH3_k127_584032_1 CRP FNR family K21563 - - 0.00000000000000000000000000000000000000105 156.0
PYH3_k127_584032_2 Universal stress protein - - - 0.00000000000000000000000000000000005898 139.0
PYH3_k127_584032_3 Universal stress protein - - - 0.00000000000000000000000000000000023 139.0
PYH3_k127_584032_4 2-nitropropane dioxygenase K00459 - 1.13.12.16 0.00000000000000000000002972 102.0
PYH3_k127_584032_5 Prokaryotic dksA/traR C4-type zinc finger - - - 0.0000001167 61.0
PYH3_k127_5859014_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 3.352e-194 612.0
PYH3_k127_5859014_1 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.0000000000000000000000000000000005595 135.0
PYH3_k127_5860642_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 1.138e-289 913.0
PYH3_k127_5860642_1 Type I GTP cyclohydrolase folE2 K09007 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005923 403.0
PYH3_k127_5860642_2 Polyprenyl synthetase K00795 - 2.5.1.1,2.5.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005099 305.0
PYH3_k127_5862795_0 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003764 361.0
PYH3_k127_5862795_1 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 291.0
PYH3_k127_5862795_2 plastoquinol--plastocyanin reductase activity - - - 0.0000000000001222 72.0
PYH3_k127_5865822_0 PFAM Alcohol dehydrogenase zinc-binding domain protein K00344 - 1.6.5.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002334 412.0
PYH3_k127_5865822_1 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007944 361.0
PYH3_k127_5865822_2 Amidohydrolase K03392 - 4.1.1.45 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 316.0
PYH3_k127_5865822_3 Glutathione S-transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004487 314.0
PYH3_k127_5865822_4 PFAM conserved - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001154 291.0
PYH3_k127_5865822_5 KR domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002161 237.0
PYH3_k127_5865822_6 N-acetyltransferase K03823 - 2.3.1.183 0.000000000000000000000000000000000000000000000000000000004149 204.0
PYH3_k127_5865822_7 Aminotransferase K09758 - 4.1.1.12 0.0000000000000000000000000000000000001096 145.0
PYH3_k127_5865822_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane - - - 0.0000000008237 67.0
PYH3_k127_5911524_0 periplasmic protein kinase ArgK and related GTPases of G3E family K07588 - - 0.000000000000000000000000000000000000000000000000000000000000003362 237.0
PYH3_k127_5911524_1 galactose-1-phosphate uridylyltransferase - - - 0.0000000000000000000000000000000000000000000000008155 194.0
PYH3_k127_5993657_0 Transcriptional regulatory protein, C terminal - - - 0.000000000000000000000000000000000000000000000000000000000000000615 236.0
PYH3_k127_5999962_0 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02621 - - 6.292e-232 740.0
PYH3_k127_5999962_1 Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule K02622 - - 6.814e-200 638.0
PYH3_k127_6034224_0 Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) K01969,K13778 - 6.4.1.4,6.4.1.5 5.423e-233 746.0
PYH3_k127_6034224_1 acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 572.0
PYH3_k127_6034224_2 Belongs to the thiolase family K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002185 496.0
PYH3_k127_6034224_3 Enoyl-(Acyl carrier protein) reductase K13774 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005802 375.0
PYH3_k127_6034224_4 Toxic component of a toxin-antitoxin (TA) module K07171 - - 0.00000000000000000000000000000000001108 141.0
PYH3_k127_6034224_5 PFAM CopG domain protein DNA-binding domain protein - - - 0.00000000000004407 78.0
PYH3_k127_6034224_6 acyl-CoA dehydrogenase K11731 - - 0.00000001617 55.0
PYH3_k127_6040161_0 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 467.0
PYH3_k127_6040161_1 Acyl-CoA dehydrogenase, C-terminal domain K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006373 476.0
PYH3_k127_6040161_2 KR domain K07535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004027 341.0
PYH3_k127_6040161_3 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001193 269.0
PYH3_k127_6040161_4 2Fe-2S -binding domain protein K03518 - 1.2.5.3 0.000000000000000000000000000000000000000000000004956 181.0
PYH3_k127_6040161_5 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000002953 149.0
PYH3_k127_6047115_0 Cytochrome D1 heme domain K15864 - 1.7.2.1,1.7.99.1 2.815e-294 911.0
PYH3_k127_6047115_1 cytochrome - - - 1.823e-239 750.0
PYH3_k127_6047115_2 Peptidase U32 K08303 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 513.0
PYH3_k127_6047115_3 Peptidase family U32 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007902 334.0
PYH3_k127_6047115_4 once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system K02193 - 3.6.3.41 0.000000000000000000000000000000000000002204 153.0
PYH3_k127_6047115_5 PFAM Cytochrome c, class I - - - 0.000000000000000000000000000005046 123.0
PYH3_k127_6047115_6 Sterol-binding domain protein - - - 0.000000000000000000000003828 111.0
PYH3_k127_6047115_7 Hemerythrin HHE cation binding domain - - - 0.00000000000000001024 93.0
PYH3_k127_6047115_8 Uncharacterized conserved protein (DUF2249) - - - 0.0000000005229 69.0
PYH3_k127_6063987_0 Diguanylate cyclase - - - 4.685e-295 936.0
PYH3_k127_6063987_1 elongation factor G K02355 - - 7.14e-294 915.0
PYH3_k127_6063987_10 Glutathione S-transferase, C-terminal domain K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003996 331.0
PYH3_k127_6063987_11 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 342.0
PYH3_k127_6063987_12 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 300.0
PYH3_k127_6063987_13 PFAM Glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002565 271.0
PYH3_k127_6063987_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001791 268.0
PYH3_k127_6063987_15 ChrR Cupin-like domain - - - 0.0000000000000000000000000000000000000000000000197 184.0
PYH3_k127_6063987_16 gluconolactonase activity K01053,K02352 - 3.1.1.17 0.000000000000000000000000000000000000000000001169 177.0
PYH3_k127_6063987_17 - - - - 0.000000000000000000000000000000000000000000004192 171.0
PYH3_k127_6063987_19 Prokaryotic cytochrome b561 K12262 - - 0.000000000000000000000000001594 130.0
PYH3_k127_6063987_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.24e-207 669.0
PYH3_k127_6063987_20 Polyketide cyclase / dehydrase and lipid transport - - - 0.00000000000000000000000006885 113.0
PYH3_k127_6063987_21 Bacterial regulatory proteins, crp family K10914 - - 0.000000000000001227 83.0
PYH3_k127_6063987_22 Glutathione S-transferase K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.00000000005126 66.0
PYH3_k127_6063987_23 hydrolase activity, acting on ester bonds - - - 0.000000001473 61.0
PYH3_k127_6063987_3 Methionine synthase K00549 - 2.1.1.14 3.407e-194 614.0
PYH3_k127_6063987_4 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 592.0
PYH3_k127_6063987_5 Mandelate Racemase Muconate Lactonizing - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 481.0
PYH3_k127_6063987_6 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 482.0
PYH3_k127_6063987_7 oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003607 422.0
PYH3_k127_6063987_8 Glutathione S-transferase, C-terminal domain K07393 GO:0003674,GO:0003824,GO:0004364,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0009636,GO:0009987,GO:0016491,GO:0016667,GO:0016672,GO:0016740,GO:0016765,GO:0042221,GO:0044424,GO:0044464,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0097237,GO:0098754,GO:0098869,GO:1990748 1.8.5.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006127 410.0
PYH3_k127_6063987_9 Xylose isomerase-like TIM barrel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001033 342.0
PYH3_k127_606434_0 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001896 614.0
PYH3_k127_606434_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006613 478.0
PYH3_k127_606434_2 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 421.0
PYH3_k127_606434_3 Peptidase family M23 K08259 - 3.4.24.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 318.0
PYH3_k127_606434_4 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K03589 - - 0.00000000000000000000000004675 110.0
PYH3_k127_606434_5 Protein of unknown function (DUF721) - - - 0.000000001222 70.0
PYH3_k127_6079366_0 peptidase M24B, X-Pro dipeptidase aminopeptidase K01262 - 3.4.11.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003114 580.0
PYH3_k127_6079366_1 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004794 420.0
PYH3_k127_6079366_2 Nucleotidyl transferase K00992 - 2.7.7.99 0.00000000000000000000000000000000000000000000000000000000000000008605 241.0
PYH3_k127_6122908_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 2.976e-300 932.0
PYH3_k127_6122908_1 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002541 538.0
PYH3_k127_6122908_2 Phosphoribulokinase / Uridine kinase family K00855 - 2.7.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004543 484.0
PYH3_k127_6122908_3 carbohydrate phosphatase activity K01086 - 3.1.3.11,3.1.3.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000222 432.0
PYH3_k127_6122908_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000009301 246.0
PYH3_k127_6122908_5 subfamily IA, variant 3 - - - 0.0000000000000000000000000001775 118.0
PYH3_k127_613037_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003484 586.0
PYH3_k127_613037_1 PFAM VanZ family protein - - - 0.000000000000000000000004033 103.0
PYH3_k127_6154256_0 Adenylate cyclase - - - 0.0000000000000002327 92.0
PYH3_k127_6158210_0 Chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB K04044 - - 1.23e-271 845.0
PYH3_k127_6158210_1 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666,K01897 - 6.2.1.3 3.715e-236 739.0
PYH3_k127_6158210_10 Rrf2 family transcriptional regulator, iron-sulfur cluster assembly K13643 - - 0.000000000000000000000000000000000000000000000000000000000000000006705 228.0
PYH3_k127_6158210_11 Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA K02533 - - 0.000000000000000000000000000000000000000000000000000000002366 207.0
PYH3_k127_6158210_12 Belongs to the HesB IscA family K13628 - - 0.0000000000000000000000000000000000000000000000000002325 193.0
PYH3_k127_6158210_13 Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA K04082 - - 0.000000000000000000000000000000000000000000000002845 181.0
PYH3_k127_6158210_14 Reversible hydration of carbon dioxide K01673 GO:0003674,GO:0003824,GO:0004089,GO:0005488,GO:0008150,GO:0008270,GO:0015976,GO:0016829,GO:0016835,GO:0016836,GO:0043167,GO:0043169,GO:0046872,GO:0046914 4.2.1.1 0.00000000000000000000000000000000000000000000005427 172.0
PYH3_k127_6158210_15 acetyltransferase - - - 0.0000000000000000000000000000007129 131.0
PYH3_k127_6158210_16 Small Multidrug Resistance protein - - - 0.000000000000000000000000004219 115.0
PYH3_k127_6158210_17 Sodium Bile acid symporter family - - - 0.0000000000000004328 91.0
PYH3_k127_6158210_18 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.0000000002632 71.0
PYH3_k127_6158210_19 Lipocalin-like domain - - - 0.0000000004722 64.0
PYH3_k127_6158210_2 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 5.672e-208 662.0
PYH3_k127_6158210_3 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 575.0
PYH3_k127_6158210_4 Belongs to the DegT DnrJ EryC1 family K02805 - 2.6.1.59 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 536.0
PYH3_k127_6158210_5 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002698 417.0
PYH3_k127_6158210_6 Glycosyl transferase family 2 K13670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002275 372.0
PYH3_k127_6158210_7 Inositol monophosphatase K01092 - 3.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002315 342.0
PYH3_k127_6158210_8 TIGRFAM Serine O-acetyltransferase K00640 - 2.3.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000026 306.0
PYH3_k127_6158210_9 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008702 241.0
PYH3_k127_6178456_0 PFAM AMP-dependent synthetase K01895 - 6.2.1.1 6.442e-267 842.0
PYH3_k127_6178456_1 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000004042 267.0
PYH3_k127_6186970_0 glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1508.0
PYH3_k127_6186970_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 5.435e-287 894.0
PYH3_k127_6186970_10 Cache domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005828 528.0
PYH3_k127_6186970_11 Belongs to the adenylyl cyclase class-4 guanylyl cyclase family K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004209 439.0
PYH3_k127_6186970_12 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001968 439.0
PYH3_k127_6186970_13 Benzoyl-CoA reductase subunit K04115 - 1.3.7.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 367.0
PYH3_k127_6186970_14 Enoyl-CoA hydratase/isomerase K07537 - 4.2.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007924 317.0
PYH3_k127_6186970_15 NAD dependent epimerase/dehydratase family K00059,K07535 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008611 305.0
PYH3_k127_6186970_16 SMART cyclic nucleotide-binding K10914 - - 0.00000000000000000000000000000000000000000000000000000000000000002088 229.0
PYH3_k127_6186970_17 translation initiation inhibitor, yjgF family - - - 0.000000000000000000000000000000000000000000000000000006967 193.0
PYH3_k127_6186970_18 ferredoxin - - - 0.0000000000000000000000000000000000002399 141.0
PYH3_k127_6186970_19 Rubrerythrin - - - 0.00000000000000000000000000004071 133.0
PYH3_k127_6186970_2 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster K00266 - 1.4.1.13,1.4.1.14 1.585e-239 747.0
PYH3_k127_6186970_20 PFAM response regulator receiver K11443 - - 0.0000000000000000000000000001236 123.0
PYH3_k127_6186970_21 Belongs to the enoyl-CoA hydratase isomerase family - - - 0.00000000000000000000000000034 116.0
PYH3_k127_6186970_22 Cytochrome c - - - 0.0000000000000959 74.0
PYH3_k127_6186970_23 ABC transporter substrate binding protein K01989 - - 0.0001024 46.0
PYH3_k127_6186970_3 Pyruvate flavodoxin/ferredoxin oxidoreductase, thiamine diP-bdg K00174 - 1.2.7.11,1.2.7.3 2.497e-223 706.0
PYH3_k127_6186970_4 2-hydroxyglutaryl-CoA dehydratase, D-component K04113 - 1.3.7.8 9.59e-211 669.0
PYH3_k127_6186970_5 Benzoyl-CoA reductase subunit K04114 - 1.3.7.8 7.386e-195 616.0
PYH3_k127_6186970_6 Enoyl-CoA hydratase/isomerase K07539 - 3.7.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006268 577.0
PYH3_k127_6186970_7 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004259 560.0
PYH3_k127_6186970_8 2-hydroxyglutaryl-CoA dehydratase, D-component K04112 - 1.3.7.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007196 562.0
PYH3_k127_6186970_9 COG0457 FOG TPR repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000685 520.0
PYH3_k127_6229371_0 Belongs to the CarB family K01955 - 6.3.5.5 0.0 1669.0
PYH3_k127_6229371_1 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002175 292.0
PYH3_k127_6229371_2 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.0000000000000000000000000000000000000000000000000000000000000000000111 238.0
PYH3_k127_6229371_3 Belongs to the Fur family K03711 - - 0.00000000000000000000000000000000000000000000000000000000000000001916 229.0
PYH3_k127_6229371_4 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000005226 184.0
PYH3_k127_6229371_5 membrane - - - 0.0000000000000000000000000000000000000000000000000901 183.0
PYH3_k127_6229371_6 - - - - 0.000000000000000000000000000000000000000008217 171.0
PYH3_k127_6229371_7 - - - - 0.000000000000000000000000000000000000001588 153.0
PYH3_k127_6229371_8 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K06186 - - 0.000000000000000000000000000000002974 136.0
PYH3_k127_6229371_9 May be involved in recombinational repair of damaged DNA K03631 - - 0.000000002194 59.0
PYH3_k127_6269062_0 P-aminobenzoate N-oxygenase AurF - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 430.0
PYH3_k127_6269062_1 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000216 408.0
PYH3_k127_6269062_2 Alpha beta hydrolase K01563 - 3.8.1.5 0.000000000000000000000009071 101.0
PYH3_k127_6270362_0 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 613.0
PYH3_k127_6270362_1 Belongs to the GPI family K01810 - 5.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002522 352.0
PYH3_k127_6270362_2 YjgF/chorismate_mutase-like, putative endoribonuclease - - - 0.0000000000000000000000000000000000000000000000000000000004331 224.0
PYH3_k127_6270362_3 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000005608 85.0
PYH3_k127_6291195_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.0 1207.0
PYH3_k127_6291195_1 AAA domain (dynein-related subfamily) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003883 445.0
PYH3_k127_6291195_10 PFAM Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000001054 141.0
PYH3_k127_6291195_11 Lipocalin-like domain - - - 0.00000000000002654 79.0
PYH3_k127_6291195_12 Adenylate cyclase K01768 - 4.6.1.1 0.00000001109 67.0
PYH3_k127_6291195_2 VWA domain containing CoxE-like protein K07161 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003307 445.0
PYH3_k127_6291195_3 Malonyl-CoA decarboxylase N-terminal domain K01578 - 4.1.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000541 426.0
PYH3_k127_6291195_4 PFAM molybdopterin dehydrogenase, FAD-binding K03519 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001817 317.0
PYH3_k127_6291195_5 peptidase U62, modulator of DNA gyrase K03592 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003772 304.0
PYH3_k127_6291195_6 [2Fe-2S] binding domain K03518 - 1.2.5.3 0.0000000000000000000000000000000000000000000000000000000000000000001596 237.0
PYH3_k127_6291195_7 Histone methylation protein DOT1 - - - 0.00000000000000000000000000000000000000000000000000000000000000006643 226.0
PYH3_k127_6291195_8 DSBA-like thioredoxin domain - - - 0.000000000000000000000000000000000000000000000000000004071 199.0
PYH3_k127_6291195_9 carbon monoxide dehydrogenase K09386 - - 0.000000000000000000000000000000000000000001511 177.0
PYH3_k127_6293580_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 0.0 1376.0
PYH3_k127_6293580_1 Protein tyrosine kinase K12132 - 2.7.11.1 0.0 1163.0
PYH3_k127_6293580_10 Cyclic nucleotide-monophosphate binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007809 268.0
PYH3_k127_6293580_11 Integral membrane protein TerC family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000008744 249.0
PYH3_k127_6293580_12 (FHA) domain - - - 0.0000000000000000000000000000000000000000000000000000235 191.0
PYH3_k127_6293580_13 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000000000000000000000008537 172.0
PYH3_k127_6293580_2 Belongs to the TPP enzyme family K01577 - 4.1.1.8 3.63e-320 985.0
PYH3_k127_6293580_3 formate-tetrahydrofolate ligase activity K01938 - 6.3.4.3 7.081e-270 875.0
PYH3_k127_6293580_4 Tripartite tricarboxylate transporter TctA family K07793 - - 1.944e-242 756.0
PYH3_k127_6293580_5 Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 1.203e-194 609.0
PYH3_k127_6293580_6 CoA-transferase family III K07749,K14471,K14472 - 2.8.3.16,2.8.3.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007875 596.0
PYH3_k127_6293580_7 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007604 497.0
PYH3_k127_6293580_8 PFAM formyl transferase domain protein K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004747 419.0
PYH3_k127_6293580_9 Serine/threonine phosphatases, family 2C, catalytic domain K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002555 351.0
PYH3_k127_6365865_0 FAD linked oxidase domain protein K06911 - - 0.0 1202.0
PYH3_k127_6365865_1 luciferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002501 334.0
PYH3_k127_6365865_2 Sulfite exporter TauE/SafE K07090 - - 0.00000000000000000000000000000000000000000000007304 185.0
PYH3_k127_6365865_3 Ankyrin repeat and kinase domain containing 1 K16289 - 2.7.11.1 0.000000000000000000000936 110.0
PYH3_k127_6365865_4 COG0501 Zn-dependent protease with chaperone function K03799 - - 0.0000000000007915 76.0
PYH3_k127_6370958_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family - - - 0.0 1455.0
PYH3_k127_6370958_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 606.0
PYH3_k127_6370958_10 Metal-sensitive transcriptional repressor - - - 0.000000000000001517 79.0
PYH3_k127_6370958_2 PFAM monooxygenase FAD-binding K20940 - 1.14.13.218 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006649 530.0
PYH3_k127_6370958_3 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002868 483.0
PYH3_k127_6370958_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001678 394.0
PYH3_k127_6370958_5 protein conserved in bacteria - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 329.0
PYH3_k127_6370958_6 PFAM secretion protein HlyD family protein K03543 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 327.0
PYH3_k127_6370958_7 DsrC like protein K11179 - - 0.0000000000000000000000000000000000000007227 152.0
PYH3_k127_6370958_8 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000002181 158.0
PYH3_k127_6370958_9 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000001422 124.0
PYH3_k127_6373388_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08309 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 454.0
PYH3_k127_6373388_1 NAD dependent epimerase dehydratase family protein K00329,K00356 - 1.6.5.3,1.6.99.3 0.0000000000000000000000001809 109.0
PYH3_k127_6388417_0 Tyrosine recombinase xerD K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004933 369.0
PYH3_k127_6388417_1 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 348.0
PYH3_k127_6388417_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000488 292.0
PYH3_k127_6388417_3 Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000001893 229.0
PYH3_k127_6388417_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.00000000000000000000000000000000000000000000000003026 185.0
PYH3_k127_6388417_5 Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.000000000000000000000000000005073 124.0
PYH3_k127_6388417_6 COG0350 Methylated DNA-protein cysteine methyltransferase K00567 - 2.1.1.63 0.0000000000000000000000003277 105.0
PYH3_k127_6404941_0 Cytochrome c554 and c-prime - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000773 603.0
PYH3_k127_6404941_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001713 556.0
PYH3_k127_6404941_10 Protein of unknown function (DUF2490) - - - 0.00000000000000000000000000000003111 134.0
PYH3_k127_6404941_11 Toxic component of a toxin-antitoxin (TA) module. An RNase K07062 - - 0.0000000000000000000000000000001761 132.0
PYH3_k127_6404941_12 COG3090 TRAP-type C4-dicarboxylate transport system, small permease component - - - 0.00000000000000000000000001606 120.0
PYH3_k127_6404941_13 bacterial (prokaryotic) histone like domain K03530 - - 0.000000000000000000001608 96.0
PYH3_k127_6404941_14 Antitoxin component of a toxin-antitoxin (TA) module - - - 0.000000000101 65.0
PYH3_k127_6404941_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K18661 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 451.0
PYH3_k127_6404941_3 Belongs to the IlvD Edd family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001235 415.0
PYH3_k127_6404941_4 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 406.0
PYH3_k127_6404941_5 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 302.0
PYH3_k127_6404941_6 HNH endonuclease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008698 269.0
PYH3_k127_6404941_7 endonuclease III K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000000002237 255.0
PYH3_k127_6404941_8 GGDEF domain K21019 - 2.7.7.65 0.00000000000000000000000000000000000000000000000000000000000005253 230.0
PYH3_k127_6404941_9 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000001267 198.0
PYH3_k127_6417543_0 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001881 428.0
PYH3_k127_6417543_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003582 441.0
PYH3_k127_6417543_2 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 399.0
PYH3_k127_6417543_3 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.000000000000000000000000000000000000000000000000000000000000000000000006834 248.0
PYH3_k127_6417543_4 Haloacid dehalogenase-like hydrolase K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000003081 250.0
PYH3_k127_6417543_5 Maf-like protein K06287 - - 0.0000000000000000000000000000000000000000000000000000000000000001212 229.0
PYH3_k127_6417543_6 rieske 2fe-2s - - - 0.0000000000000000000000000000001702 132.0
PYH3_k127_6417543_7 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000000006556 108.0
PYH3_k127_6417543_8 metal-binding, possibly nucleic acid-binding protein K07040 - - 0.000000000000000000000007517 107.0
PYH3_k127_6417543_9 Acyl transferase domain K00645 - 2.3.1.39 0.0000000000000000000002882 99.0
PYH3_k127_6419318_0 Phosphatidylethanolamine-binding protein K06910 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008523 321.0
PYH3_k127_6419318_1 COG0477 Permeases of the major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000000001613 186.0
PYH3_k127_6419318_2 membrane transporter protein K07090 - - 0.000001224 55.0
PYH3_k127_6442488_0 CoA-binding domain - - - 4.67e-217 707.0
PYH3_k127_6442488_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472,K02474,K13015 - 1.1.1.136,1.1.1.336 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001898 624.0
PYH3_k127_6442488_2 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001967 537.0
PYH3_k127_6442488_3 Glycosyl transferases group 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 359.0
PYH3_k127_6442488_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005468 284.0
PYH3_k127_6442488_5 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.00000000000000000000000000000000000000000000000000000000000000000000001778 246.0
PYH3_k127_6442488_6 PFAM Glycosyl transferase family 4 K13007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000006473 268.0
PYH3_k127_6442488_7 Male sterility protein - - - 0.00000000000000000000000000000000000000000000000000000000142 212.0
PYH3_k127_6442488_8 O-Antigen ligase - - - 0.0000000000000000000000000000000000000000000000000006086 202.0
PYH3_k127_6442488_9 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000005569 99.0
PYH3_k127_6447695_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00281,K00283 - 1.4.4.2 1.9e-276 863.0
PYH3_k127_6447695_1 Amidohydrolase K10220 - 4.2.1.83 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004415 415.0
PYH3_k127_6447695_2 Tripartite ATP-independent periplasmic transporter, DctM component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001427 259.0
PYH3_k127_6447695_3 Single cache domain 3 - - - 0.000000000000000000000000000000000000000000000000000000000000000000006496 237.0
PYH3_k127_6458483_0 dehydrogenase, E1 component K00164 - 1.2.4.2 0.0 1335.0
PYH3_k127_6458483_1 His Kinase A (phospho-acceptor) domain - - - 0.0 1208.0
PYH3_k127_6458483_10 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005226 578.0
PYH3_k127_6458483_11 The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) K00658 - 2.3.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001222 552.0
PYH3_k127_6458483_12 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005034 518.0
PYH3_k127_6458483_13 binding-protein-dependent transport systems inner membrane component K02050 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001963 423.0
PYH3_k127_6458483_14 PFAM AFG1-family ATPase K06916 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003327 443.0
PYH3_k127_6458483_15 succinate dehydrogenase fumarate reductase K00240 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005623,GO:0005886,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009060,GO:0009987,GO:0015980,GO:0016020,GO:0016491,GO:0022900,GO:0022904,GO:0044237,GO:0044464,GO:0045333,GO:0048037,GO:0051536,GO:0051537,GO:0051538,GO:0051539,GO:0051540,GO:0055114,GO:0071944 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006039 426.0
PYH3_k127_6458483_16 Pyruvate carboxyltransferase K01640 - 4.1.3.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001499 396.0
PYH3_k127_6458483_17 Putative nucleotidyltransferase substrate binding domain K07182 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000469 404.0
PYH3_k127_6458483_18 COG0604 NADPH quinone reductase and related Zn-dependent oxidoreductases K00001 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000106 398.0
PYH3_k127_6458483_19 NMT1-like family K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001941 392.0
PYH3_k127_6458483_2 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1052.0
PYH3_k127_6458483_20 PFAM ABC transporter related K02049 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008717 369.0
PYH3_k127_6458483_21 PFAM conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006981 306.0
PYH3_k127_6458483_22 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001167 285.0
PYH3_k127_6458483_23 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004071 289.0
PYH3_k127_6458483_24 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002894 286.0
PYH3_k127_6458483_25 Haem-degrading - - - 0.0000000000000000000000000000000000000000000002069 179.0
PYH3_k127_6458483_26 Response regulator receiver domain - - - 0.0000000000000000000000000000000000000000000002743 169.0
PYH3_k127_6458483_27 Pentapeptide repeats (9 copies) - - - 0.00000000000000000000000000000000000000000007465 176.0
PYH3_k127_6458483_28 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.0000000000000000000000000000000000000004272 152.0
PYH3_k127_6458483_29 Tetratricopeptide TPR_2 repeat protein - - - 0.00000000000000000000000000000000000004311 151.0
PYH3_k127_6458483_3 COG0365 Acyl-coenzyme A synthetases AMP-(fatty) acid ligases K01908 - 6.2.1.17 3.176e-292 924.0
PYH3_k127_6458483_30 Haem-degrading - - - 0.0000000000000000000000000000000005148 145.0
PYH3_k127_6458483_31 Domain of unknown function (DUF4212) - - - 0.00000000000000000000000000000004219 127.0
PYH3_k127_6458483_33 - - - - 0.000000000000000004971 87.0
PYH3_k127_6458483_34 - - - - 0.00000000000000002085 83.0
PYH3_k127_6458483_35 - - - - 0.0000000000000007053 86.0
PYH3_k127_6458483_37 Flavinator of succinate dehydrogenase K09159 - - 0.00000008603 61.0
PYH3_k127_6458483_38 - - - - 0.000001624 53.0
PYH3_k127_6458483_4 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 1.649e-282 883.0
PYH3_k127_6458483_5 Catalyzes the reversible hydration of fumarate to (S)- malate K01676 - 4.2.1.2 7.615e-256 799.0
PYH3_k127_6458483_6 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 1.336e-249 781.0
PYH3_k127_6458483_7 Belongs to the citrate synthase family K01647 - 2.3.3.1 1.072e-226 708.0
PYH3_k127_6458483_8 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes K00382 - 1.8.1.4 6.035e-195 617.0
PYH3_k127_6458483_9 Exonuclease K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003284 592.0
PYH3_k127_6467479_0 Sulfatase K01130,K01138 - 3.1.6.1 0.0 1379.0
PYH3_k127_6467479_1 NMT1-like family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001188 426.0
PYH3_k127_6467479_2 Amino acid permease K03294 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005306 406.0
PYH3_k127_6467479_3 Sulfatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001483 385.0
PYH3_k127_6467479_4 Putative MetA-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 382.0
PYH3_k127_6467479_5 Putative neutral zinc metallopeptidase K07054 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 364.0
PYH3_k127_6467479_6 Transcriptional regulator K04761 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005672 382.0
PYH3_k127_6480138_0 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 6.895e-194 611.0
PYH3_k127_6480138_1 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 360.0
PYH3_k127_6480138_2 LUD domain K00782 - - 0.00000000000000000000000000000000000000000000000000000000000000001379 228.0
PYH3_k127_6498444_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase - - - 0.0 1444.0
PYH3_k127_6498444_1 Participates in both transcription termination and antitermination K02600 - - 7.229e-217 690.0
PYH3_k127_6498444_10 Bacterial transferase hexapeptide (six repeats) - - - 0.000000000000000000000000000000000000000000000000000000001722 205.0
PYH3_k127_6498444_11 Required for maturation of 30S ribosomal subunits K09748 - - 0.0000000000000000000000000000000000000000000001453 172.0
PYH3_k127_6498444_12 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.000000000000000000000000000000000004674 144.0
PYH3_k127_6498444_2 Tryptophanyl-tRNA synthetase K01867 - 6.1.1.2 6.027e-205 655.0
PYH3_k127_6498444_3 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001646 356.0
PYH3_k127_6498444_4 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004517 349.0
PYH3_k127_6498444_5 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005988 324.0
PYH3_k127_6498444_6 Belongs to the SUA5 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003193 289.0
PYH3_k127_6498444_7 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001008 287.0
PYH3_k127_6498444_8 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007486 264.0
PYH3_k127_6498444_9 Peptidase M50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008061 268.0
PYH3_k127_6499443_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.0000000000000000000000000000000000000000000000000000000000000009455 228.0
PYH3_k127_6501426_0 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 505.0
PYH3_k127_6501426_1 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.0000000000000000000000000000000000000000000000000005938 191.0
PYH3_k127_6504068_0 Belongs to the aspartokinase family K00928 GO:0003674,GO:0003824,GO:0004072,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009507,GO:0009532,GO:0009536,GO:0009570,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019202,GO:0019752,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044422,GO:0044424,GO:0044434,GO:0044435,GO:0044444,GO:0044446,GO:0044464,GO:0046394,GO:0071704,GO:1901564,GO:1901566,GO:1901576 2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002817 590.0
PYH3_k127_6504068_1 Phospholipase D. Active site motifs. K06132 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000172 535.0
PYH3_k127_6504068_2 tRNA (Uracil-5-)-methyltransferase K03215 - 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004821 408.0
PYH3_k127_6504068_3 Inhibitor of apoptosis-promoting Bax1 K19416 - - 0.0000000000000000000000000000000000000000000000000000000000000006118 228.0
PYH3_k127_6504068_4 Histidine kinase-like ATPase domain - - - 0.00000000000000000000000002374 113.0
PYH3_k127_6506326_0 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006799 574.0
PYH3_k127_6506326_1 PFAM HpcH HpaI aldolase citrate lyase family K02510 - 4.1.2.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002438 319.0
PYH3_k127_6506326_2 ABC transporter C-terminal domain K15738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005126 281.0
PYH3_k127_6506326_3 COG2513 PEP phosphonomutase and related enzymes - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001576 280.0
PYH3_k127_6506326_4 nucleic-acid-binding protein contains PIN domain - - - 0.000000000000000000000000004403 116.0
PYH3_k127_6506326_5 Domain of unknown function (DUF4410) - - - 0.0003498 50.0
PYH3_k127_6538355_0 P-aminobenzoate N-oxygenase AurF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001692 435.0
PYH3_k127_6538355_1 Alanine dehydrogenase/PNT, C-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002151 424.0
PYH3_k127_6538355_2 Acyltransferase - - - 0.00000000000000000000000002462 124.0
PYH3_k127_6543102_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000002181 183.0
PYH3_k127_6543102_1 Protein involved in outer membrane biogenesis - - - 0.00000000000000201 89.0
PYH3_k127_6560647_0 Type I secretion system K16299 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007091 484.0
PYH3_k127_6560647_1 type I secretion membrane fusion K02022,K12537 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000575 346.0
PYH3_k127_6560647_2 enoyl-CoA hydratase K13766,K15312 - 4.2.1.18 0.0000000000000000000000000000000000000000000000000000000000348 211.0
PYH3_k127_6560647_3 Response regulator, receiver - - - 0.00000000000000000000000000000000000001082 153.0
PYH3_k127_6567719_0 pilus assembly protein tip-associated adhesin K02674 - - 3.697e-295 971.0
PYH3_k127_6567719_1 General secretion pathway protein K02459,K02672,K02680 - - 0.00000000000000000000000000000000000000000000000003002 201.0
PYH3_k127_6567719_2 Type II transport protein GspH K08084 - - 0.0000000000000000000000000000000000000001416 165.0
PYH3_k127_6567719_3 Type IV minor pilin ComP, DNA uptake sequence receptor K02655 - - 0.0000000000000000000000000001939 123.0
PYH3_k127_6567719_4 Pilus assembly protein PilX - - - 0.000000000000000000000000004008 128.0
PYH3_k127_6567719_5 type IV pilus modification protein PilV K02671 - - 0.0000000000000000000001107 110.0
PYH3_k127_6567719_6 PFAM Sporulation domain protein - - - 0.00003153 47.0
PYH3_k127_6567719_7 - - - - 0.0002209 47.0
PYH3_k127_6576213_0 PFAM Sulfatase - - - 0.0 1215.0
PYH3_k127_6576213_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 3.539e-285 882.0
PYH3_k127_6576213_2 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002739 464.0
PYH3_k127_6576213_3 PFAM Peptidase S13, D-Ala-D-Ala carboxypeptidase C K07259 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 375.0
PYH3_k127_6576213_4 protein conserved in bacteria K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000211 371.0
PYH3_k127_6576213_5 response regulator K02483,K07666,K07774 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003065 338.0
PYH3_k127_6576213_6 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004416 293.0
PYH3_k127_6576213_7 long-chain fatty acid transport protein - - - 0.000000000000000000000000000000000000000000000000000002713 207.0
PYH3_k127_6576213_8 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 - - 0.0000000000000000000000000000000000000000000002604 168.0
PYH3_k127_6592865_0 HflC and HflK could regulate a protease K04087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007432 395.0
PYH3_k127_6592865_1 Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine K02502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001476 351.0
PYH3_k127_6592865_2 Uncharacterized protein conserved in bacteria (DUF2065) K09937 - - 0.000000000000000001522 86.0
PYH3_k127_6612935_0 Long-chain fatty acid--CoA ligase K01897 - 6.2.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002587 586.0
PYH3_k127_6612935_1 Dehydrogenase K15515 - 1.2.1.81 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002572 579.0
PYH3_k127_6612935_2 Product type K16922 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003913 486.0
PYH3_k127_6612935_3 TIGRFAM Acetolactate synthase, large subunit, biosynthetic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 424.0
PYH3_k127_6612935_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001511 354.0
PYH3_k127_6612935_5 PFAM Collagen-binding surface protein Cna-like, B-type domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000745 321.0
PYH3_k127_6612935_6 COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.0000000000000000000000000000000000000000000000000002559 214.0
PYH3_k127_6612935_7 - - - - 0.000000000000000000000000000000000000000002936 162.0
PYH3_k127_6612935_9 Protein conserved in bacteria - - - 0.0000000000000000000000000000006447 143.0
PYH3_k127_6617548_0 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 - 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008674 332.0
PYH3_k127_6617548_1 PFAM O-methyltransferase, family 3 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001451 282.0
PYH3_k127_6617548_2 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family - - - 0.00000000000000000000000000000000000000000000000008102 184.0
PYH3_k127_6617548_3 Soluble lytic murein transglycosylase L domain K08309 - - 0.00000000000000000000000000000000000000002442 160.0
PYH3_k127_6646146_0 TRAP-type mannitol chloroaromatic compound transport system, large permease component - - - 5.566e-255 807.0
PYH3_k127_6646146_1 Amidase K02433 - 6.3.5.6,6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 540.0
PYH3_k127_6646146_2 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 470.0
PYH3_k127_6646146_3 Tripartite ATP-independent periplasmic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006243 331.0
PYH3_k127_6646146_4 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004815 283.0
PYH3_k127_6646146_5 Protein of unknown function (DUF3025) - - - 0.00000000000000000000000000000000000000000000365 180.0
PYH3_k127_6646146_6 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000005733 59.0
PYH3_k127_6646146_7 PFAM HD domain - - - 0.000000004091 69.0
PYH3_k127_6649777_0 radical SAM protein - - - 4.029e-194 610.0
PYH3_k127_6649777_1 Cyclic nucleotide-monophosphate binding domain K21563 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004511 283.0
PYH3_k127_6649777_2 transcriptional regulator AsnC family - - - 0.0000000000000000000000000000000000000000000000000000004816 203.0
PYH3_k127_6649777_3 overlaps another CDS with the same product name - - - 0.0000000000000000000000000000000000000000000000002745 180.0
PYH3_k127_6649777_4 Cytochrome c-type biogenesis protein K02200 - - 0.00000000000000000000000000001305 123.0
PYH3_k127_668036_0 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 514.0
PYH3_k127_668036_1 PFAM Fructosamine - - - 0.000000000000000000000000000000000000000000000000000000000000000002928 231.0
PYH3_k127_668036_2 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 - 2.1.1.297 0.0000000000000000000000000000000000000000000000000000000000000003441 246.0
PYH3_k127_668036_3 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.0000000000000000000000000000000000000000000000000007568 187.0
PYH3_k127_668036_4 Belongs to the glutaredoxin family. Monothiol subfamily K07390 - - 0.0000000000000000000000000000000000000000000001242 169.0
PYH3_k127_6682177_0 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 557.0
PYH3_k127_6682177_1 outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 389.0
PYH3_k127_6682177_10 6-phosphogluconolactonase activity - - - 0.00000000005461 76.0
PYH3_k127_6682177_2 O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway K00568 - 2.1.1.222,2.1.1.64 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 349.0
PYH3_k127_6682177_3 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001146 267.0
PYH3_k127_6682177_4 haloacid dehalogenase-like hydrolase K22292 - 3.1.3.105 0.00000000000000000000000000000000000000000000000000000000000000000000001101 249.0
PYH3_k127_6682177_5 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001645 245.0
PYH3_k127_6682177_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000002062 189.0
PYH3_k127_6682177_7 chlorophyll binding - - - 0.0000000000000000000000000000000000000000000002155 190.0
PYH3_k127_6682177_8 OmpA family K03286 - - 0.000000000000000000000000000000000003232 141.0
PYH3_k127_6682177_9 Domain of unknown function (DUF4347) - - - 0.00000000000000008941 95.0
PYH3_k127_6848703_0 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 4.7e-322 997.0
PYH3_k127_6848703_1 Alkyl sulfatase C-terminal - - - 2.483e-301 940.0
PYH3_k127_6848703_10 Response regulator of the LytR AlgR family K02477 - - 0.000000000000000000000000000000000000000000000000000000000000000000000004888 253.0
PYH3_k127_6848703_11 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008121 250.0
PYH3_k127_6848703_12 ABC transporter substrate binding protein K01989 - - 0.000000000000000000000000000000000000000000000000000000000000000000001064 250.0
PYH3_k127_6848703_13 decarboxylase K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000000000000000000002485 231.0
PYH3_k127_6848703_14 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000004201 226.0
PYH3_k127_6848703_15 hydratase decarboxylase - - - 0.00000000000000000000000000000000000000000000000000000059 203.0
PYH3_k127_6848703_16 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000002458 208.0
PYH3_k127_6848703_17 Histidine kinase - - - 0.0000000000000000000000000000000388 137.0
PYH3_k127_6848703_18 Glutathione-dependent formaldehyde-activating - - - 0.0000000000000000000000000006715 117.0
PYH3_k127_6848703_19 Belongs to the UPF0434 family K09791 - - 0.0000000000000000000001112 98.0
PYH3_k127_6848703_2 Ferrous iron transport protein B K04759 - - 4.031e-221 705.0
PYH3_k127_6848703_20 Cytochrome P460 - - - 0.000000000000000000001102 110.0
PYH3_k127_6848703_21 cytochrome - - - 0.000000000000001025 91.0
PYH3_k127_6848703_3 OPT oligopeptide transporter protein - - - 1.662e-200 640.0
PYH3_k127_6848703_4 Dienelactone hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005707 434.0
PYH3_k127_6848703_5 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001184 351.0
PYH3_k127_6848703_6 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001408 333.0
PYH3_k127_6848703_7 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002439 314.0
PYH3_k127_6848703_8 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001967 285.0
PYH3_k127_6848703_9 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001645 284.0
PYH3_k127_6929458_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.392e-267 841.0
PYH3_k127_6929458_1 cytochrome C oxidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 609.0
PYH3_k127_6929458_2 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002347 424.0
PYH3_k127_6929458_3 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006386 371.0
PYH3_k127_6929458_4 PFAM cytochrome C oxidase mono-heme subunit FixO K00405 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001702 313.0
PYH3_k127_6929458_5 FixH family K09926 - - 0.00000000000000000000008167 103.0
PYH3_k127_6929458_6 COG4736 Cbb3-type cytochrome oxidase, subunit 3 K00407 - - 0.0000000611 63.0
PYH3_k127_6936654_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 380.0
PYH3_k127_6936654_1 MotA TolQ ExbB proton channel K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000424 284.0
PYH3_k127_6936654_2 Biopolymer transport protein ExbD TolR K03559 - - 0.000000000000000000000000000000000000000001753 169.0
PYH3_k127_6936654_3 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.0000000000000000000000003561 116.0
PYH3_k127_696923_0 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001887 439.0
PYH3_k127_696923_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003598 396.0
PYH3_k127_6969341_0 Domain of unknown function (DUF3394) - - - 4.211e-304 944.0
PYH3_k127_6969341_1 Belongs to the FAD-dependent oxidoreductase 2 family. FRD SDH subfamily K00239 - 1.3.5.1,1.3.5.4 9.122e-265 829.0
PYH3_k127_6969341_10 Pfam Sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000000000000001483 259.0
PYH3_k127_6969341_11 Chalcone isomerase-like - - - 0.000000000000000000000000000000000000000000000000002655 188.0
PYH3_k127_6969341_12 PFAM conserved - - - 0.000000000000000000000000000000000000000001011 159.0
PYH3_k127_6969341_13 SAF K16845 - 4.4.1.24 0.000000000000000000000000000000000000001069 149.0
PYH3_k127_6969341_14 Succinate dehydrogenase/Fumarate reductase transmembrane subunit - - - 0.0000000000000000000000000000000001161 141.0
PYH3_k127_6969341_15 transcriptional regulator K03710 - - 0.000000000267 62.0
PYH3_k127_6969341_2 D-galactarate dehydratase K16846,K16850 - 4.2.1.7,4.4.1.24 8.996e-218 681.0
PYH3_k127_6969341_3 NMT1-like family K07080 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001269 478.0
PYH3_k127_6969341_4 ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity K06048 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002413 467.0
PYH3_k127_6969341_5 Tartrate K01677 - 4.2.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 450.0
PYH3_k127_6969341_6 Zinc-binding dehydrogenase K00344 - 1.6.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001376 383.0
PYH3_k127_6969341_7 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00245 - 1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 363.0
PYH3_k127_6969341_8 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 337.0
PYH3_k127_6969341_9 Fumarate K01678,K03780 - 4.2.1.2,4.2.1.32 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001586 322.0
PYH3_k127_6985196_0 TIGRFAM transporter, hydrophobe amphiphile efflux-1 (HAE1) family K03296,K18138 - - 0.0 1241.0
PYH3_k127_6985196_1 Outer membrane efflux protein K18139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009713 536.0
PYH3_k127_6985196_10 Histidine kinase K07638 - 2.7.13.3 0.00001569 47.0
PYH3_k127_6985196_2 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001779 460.0
PYH3_k127_6985196_3 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 419.0
PYH3_k127_6985196_4 Biotin-lipoyl like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000911 382.0
PYH3_k127_6985196_5 Catalyzes the formation of 4-diphosphocytidyl-2-C- methyl-D-erythritol from CTP and 2-C-methyl-D-erythritol 4- phosphate (MEP) K00991 - 2.7.7.60 0.0000000000000000000000000000000000000000000000000000000000000000000001902 245.0
PYH3_k127_6985196_6 YgbB family K01770 - 4.6.1.12 0.0000000000000000000000000000000000000000000000000000000000000007255 222.0
PYH3_k127_6985196_7 transcriptional regulator K07734 - - 0.0000000000000000000000000000000000000000000000003774 189.0
PYH3_k127_6985196_8 Protein of unknown function (DUF3302) - - - 0.00000000000000000000000000000000000000006897 155.0
PYH3_k127_6985196_9 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000008488 123.0
PYH3_k127_6985322_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1563.0
PYH3_k127_6985322_1 4Fe-4S binding domain K21308 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002042 453.0
PYH3_k127_6985322_2 DMSO reductase anchor subunit (DmsC) K21309 - - 0.00000000000000000000000000000000000000000000000000000000000000000008578 236.0
PYH3_k127_6985322_3 - - - - 0.00000000000007911 78.0
PYH3_k127_6985322_4 - - - - 0.00000000000008224 77.0
PYH3_k127_6985322_5 - - - - 0.0000000000001755 76.0
PYH3_k127_6991348_0 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000003348 225.0
PYH3_k127_6991348_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K21345 - 2.7.7.70 0.00000000000000000000000000000000000000000000000000000000000000005306 225.0
PYH3_k127_6991348_2 periplasmic or secreted lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000695 218.0
PYH3_k127_6991348_3 - - - - 0.00000000000000000000000000006109 124.0
PYH3_k127_7020353_0 Belongs to the citrate synthase family K01659 - 2.3.3.5 4.201e-199 640.0
PYH3_k127_7020353_1 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 482.0
PYH3_k127_7020353_2 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate K01841,K03417 - 4.1.3.30,5.4.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002905 435.0
PYH3_k127_7020353_3 COG2009 Succinate dehydrogenase fumarate reductase, cytochrome b subunit K00241 - - 0.00000000000000000000000000000000000003217 147.0
PYH3_k127_7020353_4 Succinate dehydrogenase hydrophobic membrane anchor protein K00242 - - 0.0000000000000000000000000000000000005379 148.0
PYH3_k127_7020353_5 Protein of unknown function (DUF3460) - - - 0.00000416 59.0
PYH3_k127_7038714_0 Adenylate cyclase K01768 - 4.6.1.1 5.124e-215 682.0
PYH3_k127_7038714_1 Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) K01649 - 2.3.3.13 2.141e-209 658.0
PYH3_k127_7038714_2 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.000000000000000000000000000000000000000000000000000000000000000021 225.0
PYH3_k127_7038714_3 Predicted membrane protein (DUF2069) - - - 0.000000000000000000000000000000001816 138.0
PYH3_k127_7038714_4 - K01611 - 4.1.1.50 0.00000005474 59.0
PYH3_k127_7056670_0 PFAM Aminotransferase, class V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009017 613.0
PYH3_k127_7056670_1 Belongs to the TPP enzyme family K01576 - 4.1.1.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007624 386.0
PYH3_k127_7056670_2 Peptidase family M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005501 306.0
PYH3_k127_7056670_3 serine threonine protein kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000001789 280.0
PYH3_k127_7056670_4 Bacterial SH3 domain - - - 0.00000000000000000002765 93.0
PYH3_k127_7066994_0 Transcriptional regulatory protein, C terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000005904 265.0
PYH3_k127_7066994_1 Domain of unknown function DUF108 K06989 - 1.4.1.21 0.0000000000000000000000000000000000000000000000000000000000000008419 228.0
PYH3_k127_7066994_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000005013 83.0
PYH3_k127_7066994_4 LysR substrate binding domain - - - 0.00000008907 55.0
PYH3_k127_7072180_0 Glycosyl transferase, family 4 K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000008641 268.0
PYH3_k127_7072180_1 FecR protein - - - 0.000000000000000004224 96.0
PYH3_k127_7079868_0 LemA family K03744 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002662 310.0
PYH3_k127_7079868_1 TPM domain K06872 - - 0.000000000000000000000000000000000000000000000000000000000000000000006084 246.0
PYH3_k127_7079868_2 3'-5' exonuclease - - - 0.00000000000000000000000000000000000000000000000000003315 193.0
PYH3_k127_7079868_3 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000003827 184.0
PYH3_k127_7079868_4 TPM domain - - - 0.0000000000000000000000000000000000000000000000004645 184.0
PYH3_k127_7079868_5 - - - - 0.000000000000000000000000000002059 123.0
PYH3_k127_7079868_6 restriction endonuclease K07448 - - 0.0000000000000000000000165 103.0
PYH3_k127_7079868_7 Antibiotic biosynthesis monooxygenase - - - 0.000000000000000001971 89.0
PYH3_k127_7079868_8 COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) K05770 - - 0.0000000001227 70.0
PYH3_k127_7114758_0 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 GO:0000105,GO:0003674,GO:0003824,GO:0004399,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0018130,GO:0019438,GO:0019752,GO:0030145,GO:0034641,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046872,GO:0046914,GO:0052803,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003141 484.0
PYH3_k127_7114758_1 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002667 396.0
PYH3_k127_7114758_2 Imidazoleglycerol-phosphate dehydratase K01693 - 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 329.0
PYH3_k127_7114758_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.000000000000000000000000000000000000000000000000000000000000000000002939 237.0
PYH3_k127_7118975_0 COG1960 Acyl-CoA dehydrogenases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007561 465.0
PYH3_k127_7118975_1 PFAM Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002157 340.0
PYH3_k127_7118975_2 Belongs to the helicase family. UvrD subfamily K10742 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000005088 227.0
PYH3_k127_7118975_3 Thioredoxin K05838 - - 0.0000000000000000000000000000000000000000000000000000000000000069 224.0
PYH3_k127_7118975_4 Belongs to the UPF0178 family K09768 - - 0.0000000000000000000000000000000000000000000000000000000002284 223.0
PYH3_k127_7118975_5 HNH nucleases - - - 0.000000000000000000000000000000000000007477 147.0
PYH3_k127_7118975_6 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 0.000000000000000000000000000000000006912 138.0
PYH3_k127_7118975_7 - - - - 0.0000000000000000000000000000000003871 134.0
PYH3_k127_7118975_8 TspO MBR family protein K05770 - - 0.0000000000000000000000001441 108.0
PYH3_k127_7141310_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 1.443e-235 737.0
PYH3_k127_7141310_1 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases K00174 - 1.2.7.11,1.2.7.3 4.223e-221 709.0
PYH3_k127_7141310_10 Tetratricopeptide repeat - - - 0.0000000000000000000002658 113.0
PYH3_k127_7141310_11 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor - - - 0.00000000000000001285 88.0
PYH3_k127_7141310_2 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 3.024e-197 620.0
PYH3_k127_7141310_3 2 iron, 2 sulfur cluster binding K00266,K00528,K02823 - 1.18.1.2,1.19.1.1,1.4.1.13,1.4.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006994 481.0
PYH3_k127_7141310_4 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 472.0
PYH3_k127_7141310_5 COG1013 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008788 349.0
PYH3_k127_7141310_6 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 301.0
PYH3_k127_7141310_7 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004142 312.0
PYH3_k127_7141310_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802,K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000006388 253.0
PYH3_k127_7141310_9 Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000000000000003862 250.0
PYH3_k127_7150173_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 2.215e-241 752.0
PYH3_k127_7150173_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002435 552.0
PYH3_k127_7150173_2 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001331 493.0
PYH3_k127_7150173_3 COG3170 Tfp pilus assembly protein FimV K08086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003183 423.0
PYH3_k127_7150173_4 COG0477 Permeases of the major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008357 329.0
PYH3_k127_7150173_5 Peptidase M48 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002475 327.0
PYH3_k127_7150173_6 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000001855 274.0
PYH3_k127_7150173_7 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine - - - 0.00000000000000000000000000000000000000000000000000000000000001696 222.0
PYH3_k127_7163220_0 Belongs to the GMC oxidoreductase family - - - 1.055e-195 631.0
PYH3_k127_7163220_1 Cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009698 540.0
PYH3_k127_7163220_10 COGs COG1028 Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) K00046 - 1.1.1.69 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 317.0
PYH3_k127_7163220_11 helix_turn_helix isocitrate lyase regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005541 301.0
PYH3_k127_7163220_12 CoA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 292.0
PYH3_k127_7163220_13 RDD family - - - 0.0000000000000000000000000000000000000000000000006198 179.0
PYH3_k127_7163220_14 Thioesterase superfamily protein - - - 0.000000000000000000000000162 112.0
PYH3_k127_7163220_15 4Fe-4S single cluster domain of Ferredoxin I K05337 - - 0.0000000000000000001597 99.0
PYH3_k127_7163220_2 acyl-CoA dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001729 521.0
PYH3_k127_7163220_3 13-prostaglandin reductase activity K07119 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 414.0
PYH3_k127_7163220_4 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000136 354.0
PYH3_k127_7163220_5 PFAM Alcohol dehydrogenase GroES domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002115 369.0
PYH3_k127_7163220_6 Acyl-CoA dehydrogenase, middle domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 345.0
PYH3_k127_7163220_7 KR domain K00076,K08081 - 1.1.1.159,1.1.1.206 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007641 325.0
PYH3_k127_7163220_8 Belongs to the GST superfamily K11209 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002542 323.0
PYH3_k127_7163220_9 Major Facilitator Superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004838 335.0
PYH3_k127_7193143_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 2410.0
PYH3_k127_7193143_1 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 3.454e-310 981.0
PYH3_k127_7193143_2 Pyridine nucleotide-disulphide oxidoreductase K03885 - 1.6.99.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 336.0
PYH3_k127_7193143_3 NnrU protein - - - 0.00000000000000000000000000000000000000000000000001124 187.0
PYH3_k127_7193143_4 ABC-type transport system involved in resistance to organic solvents, auxiliary component K07323 - - 0.0000000000000000000000000000000000000000000000004881 197.0
PYH3_k127_7193143_5 Thioesterase - - - 0.00000000000000000000000000000000000002341 149.0
PYH3_k127_7193143_6 glucose sorbosone K21430 - - 0.000000006442 68.0
PYH3_k127_7215243_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1388.0
PYH3_k127_7215243_1 Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain K00382 - 1.8.1.4 9.212e-258 827.0
PYH3_k127_7215243_2 The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00382,K00627 - 1.8.1.4,2.3.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001998 534.0
PYH3_k127_7215243_3 PFAM peptidase M3A and M3B, thimet oligopeptidase F K01414 - 3.4.24.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 413.0
PYH3_k127_7215243_4 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000071 356.0
PYH3_k127_7215243_5 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006606 295.0
PYH3_k127_7215243_6 Belongs to the acetyltransferase family. ArgA subfamily K14682 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000003501 221.0
PYH3_k127_7215243_7 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.0000000000000000000000000000000000000000000002607 167.0
PYH3_k127_7229355_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 5.502e-204 644.0
PYH3_k127_7229355_1 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 486.0
PYH3_k127_7229355_2 Exodeoxyribonuclease III xth K01142 - 3.1.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002415 385.0
PYH3_k127_7229355_3 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007397 341.0
PYH3_k127_7229355_4 Domain of unknown function (DUF4124) - - - 0.00000000000000000003389 98.0
PYH3_k127_7269630_0 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 415.0
PYH3_k127_7269630_1 ATPases associated with a variety of cellular activities K02013 - 3.6.3.34 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003467 304.0
PYH3_k127_7269630_2 Chromate resistance exported protein - - - 0.0000000000000000000000000000000000000000000000000000000000001186 220.0
PYH3_k127_7269630_3 PBP superfamily domain - - - 0.000000000000005108 79.0
PYH3_k127_7285527_0 Sulfate transporter antisigma-factor antagonist STAS - - - 1.5e-238 757.0
PYH3_k127_7285527_1 TIGRFAM isocitrate dehydrogenase, NADP-dependent K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 1.044e-233 728.0
PYH3_k127_7285527_2 STAS domain K03321 - - 3.996e-195 626.0
PYH3_k127_7285527_3 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 387.0
PYH3_k127_7285527_4 Urate oxidase N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000008108 262.0
PYH3_k127_7285527_5 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000003077 171.0
PYH3_k127_7285527_6 Belongs to the hyi family K01816,K22131 - 5.3.1.22,5.3.1.35 0.0000000000000000000000138 107.0
PYH3_k127_729150_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1221.0
PYH3_k127_729150_1 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 3.602e-284 896.0
PYH3_k127_729150_2 AMP-binding enzyme C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001727 604.0
PYH3_k127_729150_3 Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA K01754 GO:0006082,GO:0006520,GO:0006566,GO:0006807,GO:0008150,GO:0008152,GO:0009066,GO:0009987,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0071704,GO:1901564,GO:1901605 4.3.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000314 398.0
PYH3_k127_729150_4 membrane - - - 0.000000000000000000000000000000000002746 142.0
PYH3_k127_729150_5 Together with LptD, is involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane. Required for the proper assembly of LptD. Binds LPS and may serve as the LPS recognition site at the outer membrane K03643 - - 0.000000000000000000000000000000003481 141.0
PYH3_k127_729150_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000001411 96.0
PYH3_k127_729150_7 DNA polymerase III delta subunit K02340 - 2.7.7.7 0.00000006579 54.0
PYH3_k127_7342069_0 COG1235 Metal-dependent hydrolases of the beta-lactamase superfamily I - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002201 422.0
PYH3_k127_7342069_1 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000001095 229.0
PYH3_k127_7342069_2 Fumarylacetoacetate (FAA) hydrolase family - - - 0.00000000000000000000000000000000000000000000000000000000007081 215.0
PYH3_k127_7342069_3 pilus assembly protein PilZ K02676 - - 0.000000000000000000000000000000000000000008474 161.0
PYH3_k127_7342069_4 ankyrin repeat K06867 - - 0.0000000000000000000000000000000000005997 148.0
PYH3_k127_7342069_5 Protein of unknown function (DUF1178) - - - 0.00000000000000000000000000000000001328 140.0
PYH3_k127_7342069_6 STAS domain - - - 0.00000000004635 68.0
PYH3_k127_7347545_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 0.000000000000000000000000000000000000000000000000000000000000001317 220.0
PYH3_k127_7347545_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.000000000000000000000000000000000000000000000000000002234 193.0
PYH3_k127_7347545_2 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.00000000000000000000000000000000000006661 145.0
PYH3_k127_7347545_3 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000042 135.0
PYH3_k127_7347545_4 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000001008 75.0
PYH3_k127_7356496_0 Belongs to the 5'-nucleotidase family K11751,K17224 - 3.1.3.5,3.6.1.45 3.665e-253 792.0
PYH3_k127_7356496_1 ABC-type antimicrobial peptide transport system, permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007904 479.0
PYH3_k127_7356496_10 Sulphur oxidation protein SoxZ K17227 - - 0.0000000000000000000000000000000002802 134.0
PYH3_k127_7356496_11 Bacterial membrane protein YfhO - - - 0.0000001945 63.0
PYH3_k127_7356496_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005,K13888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 410.0
PYH3_k127_7356496_3 Peptidase family M48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008273 362.0
PYH3_k127_7356496_4 Non-canonical ABC transporter that contains transmembrane domains (TMD), which form a pore in the membrane, and an ATP-binding domain (NBD), which is responsible for energy generation. Confers resistance against macrolides K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 304.0
PYH3_k127_7356496_5 Thiosulfate-oxidizing multienzyme system protein SoxA K17222,K19713 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005507,GO:0005515,GO:0005575,GO:0005623,GO:0006091,GO:0006464,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016491,GO:0016667,GO:0016669,GO:0016740,GO:0016782,GO:0016783,GO:0018192,GO:0018193,GO:0018198,GO:0018307,GO:0019417,GO:0019538,GO:0020037,GO:0022900,GO:0036211,GO:0042597,GO:0043167,GO:0043169,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044464,GO:0046872,GO:0046906,GO:0046914,GO:0046982,GO:0046983,GO:0048037,GO:0055114,GO:0071704,GO:0097159,GO:0098822,GO:1901363,GO:1901564 1.8.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000008157 288.0
PYH3_k127_7356496_6 Tetratricopeptide repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000001042 258.0
PYH3_k127_7356496_7 Cytochrome c K17223 - - 0.00000000000000000000000000000000000000000000000001148 186.0
PYH3_k127_7356496_8 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.00000000000000000000000000000000000000000000000063 195.0
PYH3_k127_7356496_9 sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000002303 177.0
PYH3_k127_7364465_0 Phosphoesterase family - - - 1.786e-201 642.0
PYH3_k127_7364465_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000447 365.0
PYH3_k127_7364465_2 SMART metal-dependent phosphohydrolase, HD region K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000000000001179 216.0
PYH3_k127_7364465_3 Glutaredoxin - - - 0.00000000000000000000000000000000000000000000000000000006759 197.0
PYH3_k127_7364465_4 Protein chain release factor B K15034 - - 0.000000000000000000000000000000000000000005071 158.0
PYH3_k127_7364465_5 - - - - 0.0000000000000000000187 97.0
PYH3_k127_738346_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003348 473.0
PYH3_k127_738346_1 Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr) K06023 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 326.0
PYH3_k127_738346_2 Displays ATPase and GTPase activities K06958 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002738 333.0
PYH3_k127_738346_3 PFAM phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 K02806 - - 0.0000000000000000000000000000000000000000000000000000000000000575 217.0
PYH3_k127_738346_4 peptidase S16 K07157 - - 0.000000000000000000000000000000000000000000000000000000001681 220.0
PYH3_k127_738346_5 sigma 54 modulation protein K05808 - - 0.00000000000000000000000000001597 134.0
PYH3_k127_7424066_0 COG0741 Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM invasin domains) K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006345 457.0
PYH3_k127_7424066_1 Belongs to the ABC transporter superfamily K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001303 375.0
PYH3_k127_7437232_0 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001299 561.0
PYH3_k127_7437929_0 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 420.0
PYH3_k127_7437929_1 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002903 328.0
PYH3_k127_7437929_2 Belongs to the TPP enzyme family K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000001676 237.0
PYH3_k127_7437929_3 Mycolic acid cyclopropane synthetase - - - 0.000000000000000000000000000000000000000000000000005698 191.0
PYH3_k127_7437929_4 Redoxin domain protein - - - 0.00000000000000000000000000000000000000001304 160.0
PYH3_k127_7445429_0 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005635 343.0
PYH3_k127_7445429_1 COG2057 Acyl CoA acetate 3-ketoacid CoA transferase, beta subunit K01040 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000001466 269.0
PYH3_k127_747044_0 Thiolase, C-terminal domain - - - 6.944e-197 622.0
PYH3_k127_747044_1 GntR family - - - 0.00000000000000000000000000000004647 128.0
PYH3_k127_747044_2 COG0318 Acyl-CoA synthetases (AMP-forming) AMP-acid ligases II K00666 - - 0.0001548 46.0
PYH3_k127_748073_0 Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate K01952 GO:0000166,GO:0000287,GO:0003674,GO:0003824,GO:0004642,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0017076,GO:0018130,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.3.5.3 6.854e-281 878.0
PYH3_k127_748073_1 Bifunctional enoyl-CoA hydratase phosphate acetyltransferase K00625 - 2.3.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000291 292.0
PYH3_k127_751831_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K18361 - 1.17.5.1,3.1.2.25 0.0 1281.0
PYH3_k127_751831_1 4Fe-4S binding domain K18362 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007628 368.0
PYH3_k127_751831_2 ABC transporter K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002434 327.0
PYH3_k127_751831_3 branched-chain amino acid transport K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000005677 238.0
PYH3_k127_751831_4 DMSO reductase anchor subunit (DmsC) K18363 - - 0.0000000000000000000000000000000000000000000000008294 192.0
PYH3_k127_751831_5 Thioesterase - - - 0.000000000000000000000000000000000000000000002749 167.0
PYH3_k127_7520900_0 PFAM AMP-dependent synthetase and ligase K12508 - 6.2.1.34 3.632e-202 642.0
PYH3_k127_7520900_1 Protein of unknown function (DUF521) K09123 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009452 533.0
PYH3_k127_7520900_2 Amidohydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001264 415.0
PYH3_k127_7520900_3 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000002477 227.0
PYH3_k127_7520900_4 Protein of unknown function DUF126 K09128 - - 0.0000000000000000000000000000000000000000000000000000000008918 214.0
PYH3_k127_7520900_5 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions K05524 - - 0.00000000000000000000000000000000000000000000000000000008285 196.0
PYH3_k127_7520900_6 catechol 1,2-dioxygenase - - - 0.00000000000000000000000000000000007734 149.0
PYH3_k127_7520900_7 (Lipo)protein - - - 0.000000000000005126 85.0
PYH3_k127_7526807_0 Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008472 302.0
PYH3_k127_7526807_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005739 293.0
PYH3_k127_7526807_2 branched-chain amino acid transport K01996 - - 0.0000000000000000000000000000000000000000000000001451 177.0
PYH3_k127_7526807_3 Protein of unknown function (DUF1232) - - - 0.000000000000000000000000000000000006653 141.0
PYH3_k127_7526807_4 Cupin 2, conserved barrel domain protein K19547 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016853,GO:0016860,GO:0016863,GO:0016999,GO:0017000,GO:0017144,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0046872,GO:0046914,GO:0050897 5.3.3.19 0.0000000000000000000000003186 111.0
PYH3_k127_7526807_5 OmpA-like transmembrane domain K03286 - - 0.0000000000000001257 88.0
PYH3_k127_755766_0 Phage derived protein Gp49-like (DUF891) - - - 0.00000000000000000000000000000000000000007279 155.0
PYH3_k127_755766_1 Tetratricopeptide repeat - - - 0.0000000000000000000000000000007953 133.0
PYH3_k127_755766_2 Helix-turn-helix domain - - - 0.00000000000000000000000000002371 123.0
PYH3_k127_755766_3 DNA primase, small subunit - - - 0.0009014 46.0
PYH3_k127_7559726_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 2.808e-303 935.0
PYH3_k127_7559726_1 Pyruvate:ferredoxin oxidoreductase core domain II K18355 - 1.2.1.58 2.124e-198 625.0
PYH3_k127_7559726_2 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K18356 - 1.2.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000061 553.0
PYH3_k127_7559726_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K18357 - 1.2.1.58 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003253 278.0
PYH3_k127_7559726_4 Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000005825 64.0
PYH3_k127_7559726_5 Rubrerythrin - - - 0.0000932 53.0
PYH3_k127_7559949_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01539 - 3.6.3.9 5.407e-235 743.0
PYH3_k127_7572929_0 TIGRFAM ATP-dependent Clp protease ATP-binding subunit clpA K03694 - - 0.0 1180.0
PYH3_k127_7572929_1 Converts isocitrate to alpha ketoglutarate K00031 GO:0003674,GO:0003824,GO:0003862,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006551,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009081,GO:0009082,GO:0009098,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.1.1.42 1.441e-240 747.0
PYH3_k127_7572929_2 Flavocytochrome c sulphide dehydrogenase, flavin-binding K05301,K17218 - 1.8.2.1,1.8.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005287 515.0
PYH3_k127_7572929_3 This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA K01520 - 3.6.1.23 0.00000000000000000000000000000000000000000000000000000000000000000485 228.0
PYH3_k127_7572929_4 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 - - 0.00000000000000000000000000000000000000000001589 163.0
PYH3_k127_7572929_5 Cold shock K03704 - - 0.00000000000000000000000000000000001552 137.0
PYH3_k127_7572929_6 Cytochrome c, class I - - - 0.000000000000000000000001477 107.0
PYH3_k127_7575364_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 2.02e-206 659.0
PYH3_k127_7575364_1 Poly-beta-hydroxybutyrate polymerase (PhaC) N-terminus K03821 - - 2.962e-205 653.0
PYH3_k127_7575364_2 Belongs to the thiolase family K00626 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004017 606.0
PYH3_k127_7575364_3 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007438 535.0
PYH3_k127_7575364_4 Belongs to the short-chain dehydrogenases reductases (SDR) family K00023 - 1.1.1.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001119 400.0
PYH3_k127_7575364_5 ZIP Zinc transporter K16267 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002979 305.0
PYH3_k127_7575364_6 synthesis repressor, PhaR - - - 0.00000000000000000000000000000000000000000000000000000000000000000001156 250.0
PYH3_k127_7575364_7 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.00000000000000001407 83.0
PYH3_k127_7583756_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 5.793e-287 891.0
PYH3_k127_7583756_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 541.0
PYH3_k127_7583756_10 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000009246 173.0
PYH3_k127_7583756_2 PFAM Aminotransferase class I and II K14267 - 2.6.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005227 522.0
PYH3_k127_7583756_3 Required for chromosome condensation and partitioning K03529 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003497 488.0
PYH3_k127_7583756_4 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001987 462.0
PYH3_k127_7583756_5 Belongs to the transferase hexapeptide repeat family K00674 - 2.3.1.117 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 419.0
PYH3_k127_7583756_6 ABC transporter substrate binding protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000373 389.0
PYH3_k127_7583756_7 Specifically methylates the 50S ribosomal protein L3 on a specific glutamine residue K07320 - 2.1.1.298 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004756 297.0
PYH3_k127_7583756_8 Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters K06204 - - 0.00000000000000000000000000000000000000000000000000000000000000000005462 233.0
PYH3_k127_7583756_9 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000001508 205.0
PYH3_k127_7586898_0 Cytochrome c554 and c-prime - - - 2.683e-232 738.0
PYH3_k127_7586898_1 PFAM Polysulphide reductase, NrfD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006277 332.0
PYH3_k127_7586898_10 Psort location Periplasmic, score - - - 0.00000000000001468 86.0
PYH3_k127_7586898_11 PFAM cytochrome c, class I K08738 - - 0.0000000000006263 73.0
PYH3_k127_7586898_12 PFAM diacylglycerol kinase catalytic region - - - 0.000000003114 61.0
PYH3_k127_7586898_13 Cytochrome c K08738 - - 0.000000003226 62.0
PYH3_k127_7586898_14 Putative outer membrane beta-barrel porin, MtrB/PioB - - - 0.000004644 58.0
PYH3_k127_7586898_15 Cytochrome c class - - - 0.0002803 54.0
PYH3_k127_7586898_2 4Fe-4S binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000002033 246.0
PYH3_k127_7586898_3 - - - - 0.00000000000000000000000000000000000000000000000000438 199.0
PYH3_k127_7586898_4 cytochrome c5 - - - 0.00000000000000000000000000000000000000000000001564 185.0
PYH3_k127_7586898_5 Cytochrome c - - - 0.0000000000000000000000000000004925 134.0
PYH3_k127_7586898_6 Cytochrome c - - - 0.00000000000000000000000006548 124.0
PYH3_k127_7586898_7 Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process K04013,K15876 - - 0.000000000000000000006741 104.0
PYH3_k127_7586898_8 - - - - 0.00000000000000000003685 103.0
PYH3_k127_7586898_9 cytochrome - - - 0.0000000000000000000438 103.0
PYH3_k127_7587275_0 Thiol disulfide interchange protein K03673 - - 0.00000000000000000000000000000000000000000000000000000009908 201.0
PYH3_k127_7587275_1 Thiol disulfide interchange protein K03673 - - 0.000000000000000000000000000000000001079 154.0
PYH3_k127_7587275_2 Sporulation related domain - - - 0.00000000000000000000000000000000004412 138.0
PYH3_k127_7587275_3 Rhodanese-like domain - - - 0.0000000000000000000000000000442 123.0
PYH3_k127_7587275_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000002974 104.0
PYH3_k127_7593694_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 572.0
PYH3_k127_7593694_1 PFAM Polysulphide reductase, NrfD K00185 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 383.0
PYH3_k127_7593694_2 Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001814 290.0
PYH3_k127_760886_0 Pfam:DUF1446 - - - 3.316e-221 701.0
PYH3_k127_760886_1 Belongs to the phosphoglycerate mutase family K15634 - 5.4.2.12 0.00000000000000000000000000000000000000000000000000000000000000000002358 237.0
PYH3_k127_7635547_0 Protein of unknown function (DUF1211) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007161 310.0
PYH3_k127_7635547_1 Predicted membrane protein (DUF2238) K08984 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002102 304.0
PYH3_k127_7635547_10 Lipase (class 3) - - - 0.0000106 59.0
PYH3_k127_7635547_2 Serine threonine protein kinase K08884,K12132 - 2.7.11.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004525 294.0
PYH3_k127_7635547_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000008671 296.0
PYH3_k127_7635547_4 glyoxalase bleomycin resistance protein dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000009137 223.0
PYH3_k127_7635547_5 Glutathione-dependent formaldehyde-activating enzyme - - - 0.0000000000000000000000000000000000000000000000000482 191.0
PYH3_k127_7635547_6 - - - - 0.000000000000000000000000000000000000000388 157.0
PYH3_k127_7635547_7 Domain of unknown function (DUF202) K00389 - - 0.00000000000000000000000000000003071 131.0
PYH3_k127_7635547_8 Protein of unknown function, DUF488 - - - 0.0000000000000000000000000000248 128.0
PYH3_k127_7635547_9 - - - - 0.0000000007154 62.0
PYH3_k127_764407_0 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000003071 180.0
PYH3_k127_764803_0 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 443.0
PYH3_k127_764803_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001058 303.0
PYH3_k127_764803_2 Forms part of the polypeptide exit tunnel K02926 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007878 302.0
PYH3_k127_764803_3 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000003571 166.0
PYH3_k127_764803_4 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.0000000000000000000000000000000000000009867 159.0
PYH3_k127_764803_5 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.00000000000000000000000000000003192 137.0
PYH3_k127_7669277_0 rieske 2fe-2s K00499 - 1.14.15.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002882 506.0
PYH3_k127_7669277_1 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K18979 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003019 460.0
PYH3_k127_7669277_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 314.0
PYH3_k127_7669277_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002745 272.0
PYH3_k127_7669277_4 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000228 138.0
PYH3_k127_7669277_5 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03602 - 3.1.11.6 0.0000000000000000003199 90.0
PYH3_k127_7680506_0 Belongs to the sulfate adenylyltransferase family K00958 - 2.7.7.4 8.907e-212 663.0
PYH3_k127_7680506_1 reductase, alpha subunit K00394 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003214 597.0
PYH3_k127_7680506_2 Adenosine-5'-phosphosulfate reductase beta subunit K00395 - 1.8.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002731 267.0
PYH3_k127_7680506_3 Peptidase M48 - - - 0.0000000000000000007198 88.0
PYH3_k127_7697602_0 Tetratricopeptide repeats K12132 - 2.7.11.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003735 387.0
PYH3_k127_7743157_0 AMP-binding enzyme C-terminal domain K00666 - - 2.459e-271 842.0
PYH3_k127_7743157_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease K02342 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004162 281.0
PYH3_k127_7743157_2 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03469 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000004033 231.0
PYH3_k127_7743157_3 enoyl-CoA hydratase - - - 0.0000000000000000000000001182 113.0
PYH3_k127_7756379_0 Penicillin-binding protein 2 K05515 - 3.4.16.4 6.639e-264 835.0
PYH3_k127_7756379_1 Isocitrate lyase K01637 - 4.1.3.1 3.108e-225 705.0
PYH3_k127_7756379_2 Bifunctional enzyme which can phosphorylate or dephosphorylate isocitrate dehydrogenase (IDH) on a specific serine residue. This is a regulatory mechanism which enables bacteria to bypass the Krebs cycle via the glyoxylate shunt in response to the source of carbon. When bacteria are grown on glucose, IDH is fully active and unphosphorylated, but when grown on acetate or ethanol, the activity of IDH declines drastically concomitant with its phosphorylation K00906 - 2.7.11.5 7.45e-221 702.0
PYH3_k127_7756379_3 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001975 482.0
PYH3_k127_7756379_4 Involved in formation and maintenance of cell shape K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000231 224.0
PYH3_k127_7756379_5 Rod shape-determining protein MreD K03571 - - 0.00000000000000000000000000000000000000000000000203 184.0
PYH3_k127_7756379_6 - - - - 0.000000000000000000000000000002265 130.0
PYH3_k127_7766850_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K07303 - 1.3.99.16 0.0 1097.0
PYH3_k127_7766850_1 DNA polymerase X family K02347 - - 2.471e-228 720.0
PYH3_k127_7766850_10 Sulphur oxidation protein SoxZ - - - 0.0000000000000000000000000000000000000265 145.0
PYH3_k127_7766850_11 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000004735 154.0
PYH3_k127_7766850_12 - - - - 0.0000000000000000001323 93.0
PYH3_k127_7766850_13 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000001246 97.0
PYH3_k127_7766850_2 Mycolic acid cyclopropane synthetase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001734 524.0
PYH3_k127_7766850_3 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000167 502.0
PYH3_k127_7766850_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002263 387.0
PYH3_k127_7766850_5 [2Fe-2S] binding domain K07302 - 1.3.99.16 0.0000000000000000000000000000000000000000000000000000000000000000005145 232.0
PYH3_k127_7766850_6 Carboxymuconolactone decarboxylase family K01607 - 4.1.1.44 0.00000000000000000000000000000000000000000000000006125 183.0
PYH3_k127_7766850_7 S-Adenosylmethionine synthetase K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000001753 171.0
PYH3_k127_7766850_8 cytochrome c K17223 - - 0.000000000000000000000000000000000000000002743 170.0
PYH3_k127_7766850_9 Sulfur oxidation protein SoxY K17226 - - 0.0000000000000000000000000000000000000002889 156.0
PYH3_k127_7863279_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 1.764e-237 742.0
PYH3_k127_7863279_1 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.0000000000000000000000000000000000000000000000000000000000000000002254 242.0
PYH3_k127_7863279_2 Stress-induced protein - - - 0.0000000000000000000000000000000000000000000000001756 181.0
PYH3_k127_7863279_3 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000002457 106.0
PYH3_k127_7907047_0 cytochrome d1, heme region K19345 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000646 342.0
PYH3_k127_7907047_1 Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme K02302,K02303 - 1.3.1.76,2.1.1.107,4.99.1.4 0.0000000000000000000000000000000000002343 148.0
PYH3_k127_7907047_2 Cytochrome C oxidase, cbb3-type, subunit III K19344 - - 0.0000000000000000000000000000001095 126.0
PYH3_k127_7917354_0 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004669 544.0
PYH3_k127_7917354_1 Part of the tripartite ATP-independent periplasmic (TRAP) transport system - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001324 470.0
PYH3_k127_7917354_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003734 430.0
PYH3_k127_7917354_3 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000007198 217.0
PYH3_k127_7917354_4 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000000000000000009806 185.0
PYH3_k127_7917354_5 Modulates RecA activity K03565 - - 0.00000000000000000000000001909 118.0
PYH3_k127_791920_0 Belongs to the enoyl-CoA hydratase isomerase family K01692 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005949 398.0
PYH3_k127_791920_1 Alpha/beta hydrolase family K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000649 324.0
PYH3_k127_791920_2 Endonuclease Exonuclease phosphatase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003515 282.0
PYH3_k127_791920_3 COGs COG4446 conserved - - - 0.00000000000000000000000000000000001996 141.0
PYH3_k127_791920_4 Acetolactate synthase K01652 - 2.2.1.6 0.000000000000000001524 87.0
PYH3_k127_7989299_0 dihydroorotase multifunctional complex type K01465 - 3.5.2.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007701 541.0
PYH3_k127_7989299_1 Belongs to the ATCase OTCase family K00609 - 2.1.3.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 514.0
PYH3_k127_7989299_10 Belongs to the UPF0250 family K09158 - - 0.00000000000000000000000007249 119.0
PYH3_k127_7989299_2 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 492.0
PYH3_k127_7989299_3 Branched-chain amino acid aminotransferase 4-amino-4-deoxychorismate lyase K00824 - 2.6.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004853 365.0
PYH3_k127_7989299_4 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 310.0
PYH3_k127_7989299_5 Belongs to the UPF0301 (AlgH) family K07735 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002706 274.0
PYH3_k127_7989299_6 Belongs to the DNA photolyase family K01669 - 4.1.99.3 0.00000000000000000000000000000000000000000000000000000000000000001033 233.0
PYH3_k127_7989299_7 Pyrimidine operon attenuation protein uracil phosphoribosyltransferase K02825 - 2.4.2.9 0.0000000000000000000000000000000000000000000000000000002764 200.0
PYH3_k127_7989299_8 Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate K03801 - 2.3.1.181 0.00000000000000000000000000000000008284 141.0
PYH3_k127_7989299_9 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000006212 120.0
PYH3_k127_7990164_0 Endoribonuclease that plays a central role in RNA processing and decay. Required for the maturation of 5S and 16S rRNAs and the majority of tRNAs. Also involved in the degradation of most mRNAs K08300 - 3.1.26.12 4.231e-264 823.0
PYH3_k127_7990164_1 Responsible for synthesis of pseudouridine from uracil K06179 - 5.4.99.24 0.0000000000000000000000005566 108.0
PYH3_k127_8054229_0 Involved in lipid A export and possibly also in glycerophospholipid export and for biogenesis of the outer membrane. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation K02021,K11085 - - 1.542e-225 719.0
PYH3_k127_8054229_1 TonB-dependent Receptor Plug K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 507.0
PYH3_k127_8054229_2 Glycosyltransferase family 9 (heptosyltransferase) K02849 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007907 448.0
PYH3_k127_8054229_3 Glycosyltransferase Family 4 K02844 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005721 373.0
PYH3_k127_8054229_4 Sel1-like repeats. K07126 - - 0.00000000000000000000000000000000000000000000000000002903 203.0
PYH3_k127_8054229_5 Periplasmic binding protein K02016,K06858 - - 0.00000000000000000000000000000000000001187 159.0
PYH3_k127_8054229_6 Glycosyl transferases group 1 - - - 0.000000000002787 71.0
PYH3_k127_8055453_0 mechanosensitive ion channel - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005198 377.0
PYH3_k127_8055453_1 PFAM sulfatase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005221 343.0
PYH3_k127_8055453_2 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
PYH3_k127_8055453_3 Amidohydrolase K01686 - 4.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000005111 260.0
PYH3_k127_8055453_4 CBS domain - - - 0.000000000000000000000000000000000000000000974 173.0
PYH3_k127_8055453_5 - - - - 0.0000000000000000000000001009 109.0
PYH3_k127_808868_0 CoA-binding domain protein K09181 - - 7.245e-206 652.0
PYH3_k127_808868_1 Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) K01626 - 2.5.1.54 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004671 503.0
PYH3_k127_808868_2 cytochrome P450 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007817 493.0
PYH3_k127_808868_3 Involved in the import of queuosine (Q) precursors, required for Q precursor salvage K09125 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000229 379.0
PYH3_k127_808868_4 Serine aminopeptidase, S33 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000007391 277.0
PYH3_k127_808868_5 Transposase IS200 like K07491 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000485 251.0
PYH3_k127_808868_6 lactoylglutathione lyase activity K08234 - - 0.00000000000000000000000000003577 132.0
PYH3_k127_8125240_0 Receptor family ligand binding region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002058 601.0
PYH3_k127_8125240_1 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003383 484.0
PYH3_k127_8125240_10 4Fe-4S dicluster domain - - - 0.0000000000000000000000000001039 122.0
PYH3_k127_8125240_11 Protein of unknown function (DUF3306) - - - 0.0000000000000000000002721 108.0
PYH3_k127_8125240_2 Branched-chain amino acid transport system / permease component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007071 471.0
PYH3_k127_8125240_3 Branched-chain amino acid transport system / permease component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009614 432.0
PYH3_k127_8125240_4 Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH K02379 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004846 385.0
PYH3_k127_8125240_5 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006249 352.0
PYH3_k127_8125240_6 ATPases associated with a variety of cellular activities - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000197 353.0
PYH3_k127_8125240_7 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000004123 241.0
PYH3_k127_8125240_8 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000008911 188.0
PYH3_k127_8125240_9 Protein of unknown function (DUF3305) - - - 0.0000000000000000000000000000000000133 146.0
PYH3_k127_817277_0 Belongs to the methyltransferase superfamily K07444 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001339 469.0
PYH3_k127_817277_1 PFAM ABC transporter related K01990,K09695 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 413.0
PYH3_k127_817277_2 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006619 296.0
PYH3_k127_817277_3 ABC-2 type transporter K09694 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005231 297.0
PYH3_k127_817277_4 hydrolase of the alpha beta superfamily K07018 - - 0.0000000000000369 72.0
PYH3_k127_8198320_0 Belongs to the LDH2 MDH2 oxidoreductase family K13609,K16844 - 1.1.1.338,1.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 366.0
PYH3_k127_8198320_1 dienelactone hydrolase K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000009374 270.0
PYH3_k127_8198320_2 belongs to the aldehyde dehydrogenase family K00128,K22187 - 1.2.1.3 0.000000000000000000000000000000000000000000000003717 188.0
PYH3_k127_820868_0 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 589.0
PYH3_k127_820868_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 GO:0003674,GO:0003824,GO:0004774,GO:0004776,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0016874,GO:0016877,GO:0016878,GO:0031974,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0070013 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005434 501.0
PYH3_k127_820868_2 Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate K00864 GO:0003674,GO:0003824,GO:0004370,GO:0005975,GO:0006066,GO:0006071,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019400,GO:0019751,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0071704,GO:1901615 2.7.1.30 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006497 451.0
PYH3_k127_820868_3 MAPEG family - - - 0.00000000000000002605 86.0
PYH3_k127_820868_4 Tripartite tricarboxylate transporter family receptor - - - 0.000000006356 57.0
PYH3_k127_8245493_0 Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX K00228 GO:0003674,GO:0005488,GO:0005515,GO:0042802,GO:0042803,GO:0046983 1.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003444 442.0
PYH3_k127_8245493_1 Belongs to the GARS family K01945 - 6.3.4.13 0.00000000000000000000000004563 108.0
PYH3_k127_827724_0 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002305 599.0
PYH3_k127_8310173_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002599 598.0
PYH3_k127_8310173_1 Belongs to the heme-copper respiratory oxidase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000002871 253.0
PYH3_k127_8310173_2 Hemerythrin HHE cation binding domain - - - 0.0000000000000000008015 92.0
PYH3_k127_8323122_0 Ion channel K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002303 343.0
PYH3_k127_8323122_1 Competence protein ComEC Rec2 K02238 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007079 294.0
PYH3_k127_8323122_2 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000000001824 188.0
PYH3_k127_8323122_3 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.00003934 46.0
PYH3_k127_8330631_0 Tripartite tricarboxylate transporter TctA family K07793 - - 1.503e-213 672.0
PYH3_k127_8330631_1 Mycolic acid cyclopropane synthetase - - - 0.0000000000000000000000000000000000000000000000000000000000005257 218.0
PYH3_k127_8355820_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 7.989e-312 968.0
PYH3_k127_8355820_1 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000002456 205.0
PYH3_k127_8355820_2 Belongs to the UPF0312 family - - - 0.0000000000000000000000000000000000000000000000000000003344 200.0
PYH3_k127_8355820_3 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.00000000000000000000000000000000000000007351 154.0
PYH3_k127_8355820_4 exopolyphosphatase K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000001035 129.0
PYH3_k127_8356960_0 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 - 6.5.1.2 1.451e-241 764.0
PYH3_k127_8356960_1 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 1.287e-234 738.0
PYH3_k127_8356960_2 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 398.0
PYH3_k127_8356960_3 Purine nucleoside phosphorylase which is highly specific for 6-oxopurine nucleosides. Cleaves guanosine or inosine to respective bases and sugar-1-phosphate molecules. Involved in purine salvage K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005348 342.0
PYH3_k127_8356960_4 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003073 268.0
PYH3_k127_8356960_5 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.0000000000000000000000000000000000000000000000000000000008496 218.0
PYH3_k127_8376989_0 FAD binding domain K07077 - - 5.836e-222 703.0
PYH3_k127_8376989_1 COG0028 Thiamine pyrophosphate-requiring enzymes acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase K01652 - 2.2.1.6 2.096e-197 665.0
PYH3_k127_8376989_10 MarC family integral membrane protein K05595 - - 0.00007138 47.0
PYH3_k127_8376989_2 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006222 609.0
PYH3_k127_8376989_3 Phosphotransferase enzyme family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000129 513.0
PYH3_k127_8376989_4 KR domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 326.0
PYH3_k127_8376989_5 Domain present in PSD-95, Dlg, and ZO-1/2. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000267 287.0
PYH3_k127_8376989_6 Metal dependent phosphohydrolases with conserved 'HD' motif. - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002492 250.0
PYH3_k127_8376989_7 Glutathione S-transferase K00799 - 2.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000005515 233.0
PYH3_k127_8376989_8 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 - - 0.000000000000000000000000000000000000000000000001064 181.0
PYH3_k127_8376989_9 small protein containing a coiled-coil domain - - - 0.00000000000001117 76.0
PYH3_k127_8378819_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1310.0
PYH3_k127_8378819_1 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00058 - 1.1.1.399,1.1.1.95 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007761 530.0
PYH3_k127_8378819_2 Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine K00831 - 2.6.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001821 517.0
PYH3_k127_8378819_3 chorismate mutase K14170 - 4.2.1.51,5.4.99.5 0.00000000000000000000000000000000000000000000000000000000000000000001132 254.0
PYH3_k127_8378819_4 OmpA family K03286 - - 0.000006379 50.0
PYH3_k127_8437475_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 3.519e-312 964.0
PYH3_k127_8437475_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 3.646e-205 652.0
PYH3_k127_8437475_10 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 GO:0003674,GO:0003676,GO:0003723,GO:0003725,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004525,GO:0004540,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0032296,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0140098,GO:1901360,GO:1901363 3.1.26.3 0.0000000000000000000000000000000000000000000000000000000000000000277 229.0
PYH3_k127_8437475_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.00000000000000000000000004066 121.0
PYH3_k127_8437475_12 Domain of unknown function (DUF4845) - - - 0.00000000000001056 86.0
PYH3_k127_8437475_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003691 602.0
PYH3_k127_8437475_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003176 400.0
PYH3_k127_8437475_4 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001364 386.0
PYH3_k127_8437475_5 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004644 360.0
PYH3_k127_8437475_6 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008483 326.0
PYH3_k127_8437475_7 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 298.0
PYH3_k127_8437475_8 negative regulator of sigma E activity K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000003939 268.0
PYH3_k127_8437475_9 Involved in DNA repair and RecF pathway recombination K03584 - - 0.0000000000000000000000000000000000000000000000000000000000000000009835 250.0
PYH3_k127_8438519_0 Cytochrome P450 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 428.0
PYH3_k127_8438519_1 Metallo-beta-lactamase superfamily - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004283 358.0
PYH3_k127_8438519_2 Probable molybdopterin binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000604 310.0
PYH3_k127_8438519_3 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000000000000000000000000001273 250.0
PYH3_k127_8438519_4 Phasin protein - - - 0.00000000000000000000000000000000000000000000000001548 186.0
PYH3_k127_8438519_5 Etoposide-induced protein 2.4 (EI24) - - - 0.00000000000000000000000000000000000000000004707 172.0
PYH3_k127_8438519_6 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.0000000000000003546 79.0
PYH3_k127_8449205_0 Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transduction protein PII (GlnB) which indicates the nitrogen status of the cell K00982 - 2.7.7.42,2.7.7.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000115 510.0
PYH3_k127_8449205_1 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003814 482.0
PYH3_k127_8449205_2 Zinc-finger domain - - - 0.0000000000000000001164 101.0
PYH3_k127_8449205_3 heptosyltransferase II K02843 - - 0.000000000000003859 79.0
PYH3_k127_8468218_0 Cysteine-rich domain K18928 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000922 349.0
PYH3_k127_8468218_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 334.0
PYH3_k127_8468218_2 Histidine-specific methyltransferase, SAM-dependent - - - 0.000000000000000000000000000000000000000000000000000000000000000007543 231.0
PYH3_k127_8483893_0 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002853 591.0
PYH3_k127_8483893_1 O-methyltransferase activity - - - 0.00000000000000000000004328 100.0
PYH3_k127_8485960_0 Tripartite tricarboxylate transporter TctA family - - - 8.666e-226 708.0
PYH3_k127_8485960_1 Tripartite tricarboxylate transporter TctB family - - - 0.000000000000000000000004796 110.0
PYH3_k127_8500107_0 FAD dependent oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004064 573.0
PYH3_k127_8500107_1 Fatty acid desaturase K00507 - 1.14.19.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 372.0
PYH3_k127_8507447_0 Dihydrodipicolinate synthetase family K01714 - 4.3.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006151 413.0
PYH3_k127_8507447_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000105 301.0
PYH3_k127_8507447_2 Belongs to the AlaDH PNT family K00259 - 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 299.0
PYH3_k127_8507447_3 Domain of unknown function (DUF1841) - - - 0.000000000000000000000000000000000000000000000000000001496 194.0
PYH3_k127_8507447_4 Cytochrome c - - - 0.000000000000000000000000000000003114 130.0
PYH3_k127_8507447_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000005288 111.0
PYH3_k127_8507447_6 Part of a membrane complex involved in electron transport K03616 - - 0.000000000000000000000008553 114.0
PYH3_k127_8511115_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1507.0
PYH3_k127_8511115_1 4Fe-4S dicluster domain - - - 2.763e-204 651.0
PYH3_k127_8511115_10 - - - - 0.00000002863 58.0
PYH3_k127_8511115_2 TIGRFAM chromate transporter, chromate ion transporter (CHR) family K07240 - - 1.362e-202 641.0
PYH3_k127_8511115_3 4Fe-4S dicluster domain K00124,K07307 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007223 398.0
PYH3_k127_8511115_4 formate dehydrogenase K00127 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004593 347.0
PYH3_k127_8511115_5 Destroys radicals which are normally produced within the cells and which are toxic to biological systems K04565 - 1.15.1.1 0.0000000000000000000000000000000000000000000000000000000003138 213.0
PYH3_k127_8511115_6 Chaperone protein TorD - - - 0.000000000000000000000000000001879 132.0
PYH3_k127_8511115_7 Chromate resistance exported protein - - - 0.0000000000000000000000005055 104.0
PYH3_k127_8511115_8 - - - - 0.0000000000000000000001548 113.0
PYH3_k127_8511115_9 - - - - 0.000000000000001515 87.0
PYH3_k127_8528136_0 Heat shock 70 kDa protein K04043 - - 0.0 1053.0
PYH3_k127_8528136_1 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009458 581.0
PYH3_k127_8528136_2 Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons K03705 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009663 454.0
PYH3_k127_8528136_3 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 354.0
PYH3_k127_8528136_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003897 311.0
PYH3_k127_8528136_5 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006967 286.0
PYH3_k127_8528136_6 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000003796 154.0
PYH3_k127_8528136_7 May be involved in recombinational repair of damaged DNA K03631 - - 0.0000000000000001507 91.0
PYH3_k127_8528136_8 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.000000000006002 65.0
PYH3_k127_8549591_0 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696,K06001 - 4.2.1.20 7.405e-245 762.0
PYH3_k127_8549591_1 catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 6.607e-225 713.0
PYH3_k127_8549591_2 NAD NADP octopine nopaline dehydrogenase K04940 - 1.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000954 489.0
PYH3_k127_8549591_3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006971 335.0
PYH3_k127_8549591_4 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000444 282.0
PYH3_k127_8549591_5 COG2801 Transposase and inactivated derivatives K07497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003584 250.0
PYH3_k127_8549591_6 helix_turn_helix ASNC type K03719 - - 0.000000000000000000000000000000000000000000000000000000000005202 211.0
PYH3_k127_8549591_7 COG1014 Pyruvate ferredoxin oxidoreductase and related 2-oxoacid ferredoxin oxidoreductases, gamma subunit K00180 - 1.2.7.8 0.00000000000000000000000000000000000000000000001219 187.0
PYH3_k127_8549591_8 PFAM Sel1 domain protein repeat-containing protein K07126 - - 0.0000000001991 64.0
PYH3_k127_8549591_9 Catalyzes the NAD( )-dependent oxidation of L-carnitine to 3-dehydrocarnitine K00074 - 1.1.1.157 0.0009448 50.0
PYH3_k127_8550479_0 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000524 308.0
PYH3_k127_8550479_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001929 287.0
PYH3_k127_8550479_2 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003586 259.0
PYH3_k127_8550479_3 branched-chain amino acid K01995 - - 0.00000000000000000000000000000001709 143.0
PYH3_k127_8554435_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1055.0
PYH3_k127_8554435_1 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000244 471.0
PYH3_k127_8554435_2 (ABC) transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006701 343.0
PYH3_k127_8554435_3 Pterin binding enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001354 250.0
PYH3_k127_8554435_4 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004693 244.0
PYH3_k127_8554435_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000000000000000000000000000000000000000000000000000003721 225.0
PYH3_k127_8554435_6 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000001024 140.0
PYH3_k127_8632082_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 3.464e-199 633.0
PYH3_k127_8634273_0 Belongs to the ABC transporter superfamily K02031,K02032 - - 6.67e-209 662.0
PYH3_k127_8634273_1 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 595.0
PYH3_k127_8634273_10 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) - - - 0.000000000000000000000000000000000000000005054 160.0
PYH3_k127_8634273_11 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.000000000000000000000000000000000000000006342 164.0
PYH3_k127_8634273_12 PFAM Electron transfer flavoprotein alpha beta-subunit K03521 - - 0.00000000000000000000000000001395 118.0
PYH3_k127_8634273_13 PFAM Short-chain dehydrogenase reductase SDR - - - 0.0000000000000000002544 88.0
PYH3_k127_8634273_2 thiolase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006255 558.0
PYH3_k127_8634273_3 Peptidase family M28 K01295 - 3.4.17.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002927 500.0
PYH3_k127_8634273_4 fad dependent oxidoreductase K19746 - 1.4.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005569 462.0
PYH3_k127_8634273_5 COG0601 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004421 419.0
PYH3_k127_8634273_6 Class II Aldolase and Adducin N-terminal domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001831 345.0
PYH3_k127_8634273_7 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 339.0
PYH3_k127_8634273_8 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000003633 218.0
PYH3_k127_8634273_9 nucleic-acid-binding protein containing a Zn-ribbon K07068 - - 0.0000000000000000000000000000000000000000009382 163.0
PYH3_k127_8643930_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K07787 - - 0.0 1545.0
PYH3_k127_8643930_1 Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly K11942 GO:0000166,GO:0000287,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0006139,GO:0006163,GO:0006637,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009117,GO:0009150,GO:0009259,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016853,GO:0016866,GO:0017076,GO:0017111,GO:0019001,GO:0019637,GO:0019693,GO:0019842,GO:0031419,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0034784,GO:0035383,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043603,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0046872,GO:0046906,GO:0047727,GO:0048037,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901360,GO:1901363,GO:1901564 5.4.99.13 0.0 1532.0
PYH3_k127_8643930_2 Domain of unknown function (DUF4070) - - - 4.732e-219 688.0
PYH3_k127_8643930_3 Amidohydrolase K07045 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003009 414.0
PYH3_k127_8643930_4 Barrel-sandwich domain of CusB or HlyD membrane-fusion - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001745 410.0
PYH3_k127_8643930_5 Class II Aldolase and Adducin N-terminal domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001186 302.0
PYH3_k127_8643930_6 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003222 280.0
PYH3_k127_8643930_7 cyclopropane-fatty-acyl-phospholipid synthase K16868 - 2.1.1.265 0.000000000000000000000000000000000000000000000000000000001242 213.0
PYH3_k127_8643930_8 PFAM Methyltransferase type 11 - - - 0.00000000000000000000000002625 117.0
PYH3_k127_8643930_9 Outer membrane efflux protein - - - 0.000000006042 64.0
PYH3_k127_8650834_0 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004981 317.0
PYH3_k127_8650834_1 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000331 289.0
PYH3_k127_8650834_2 PFAM Mammalian cell entry related domain protein K02067 - - 0.0000000000000000000000000000000000000005411 159.0
PYH3_k127_8650834_3 Preprotein translocase subunit TatD K03424 - - 0.0000000000000000002128 96.0
PYH3_k127_8659311_0 Acyl-CoA dehydrogenase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001193 560.0
PYH3_k127_8659311_1 Putative esterase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006962 391.0
PYH3_k127_8659311_2 NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase K00020 - 1.1.1.31 0.000000000000000000000000000000000000000000127 162.0
PYH3_k127_8659311_3 Sterol carrier protein - - - 0.0000000000000001738 85.0
PYH3_k127_8659311_4 acyl-CoA transferases carnitine dehydratase - - - 0.0001944 45.0
PYH3_k127_8659719_0 gamma-glutamyltransferase K00681 - 2.3.2.2,3.4.19.13 3.439e-210 665.0
PYH3_k127_8659719_1 Pfam Enoyl-CoA hydratase isomerase K13816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000008484 300.0
PYH3_k127_8659719_2 Deoxynucleoside kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006986 285.0
PYH3_k127_8659719_3 Iron-containing redox enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000185 248.0
PYH3_k127_8659719_4 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine K00950 - 2.7.6.3 0.00000000000000000000000000000000000000000001825 164.0
PYH3_k127_8659719_5 Histidine kinase K10715 - 2.7.13.3 0.0000000000000000000000000000000000000001383 160.0
PYH3_k127_8661123_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 2.932e-246 770.0
PYH3_k127_8661123_1 PFAM Uncharacterised protein family UPF0027 K14415 - 6.5.1.3 4.194e-228 713.0
PYH3_k127_8661123_2 MoeA N-terminal region (domain I and II) K03750 - 2.10.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001452 516.0
PYH3_k127_8661123_3 COG0477 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001733 364.0
PYH3_k127_8661123_4 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000009488 257.0
PYH3_k127_868989_0 Vitamin B12 dependent methionine synthase activation region K00548 - 2.1.1.13 0.0 1678.0
PYH3_k127_868989_1 Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA K03498 - - 4.211e-206 653.0
PYH3_k127_868989_2 PFAM TrkA-N domain protein K03499 - - 1.864e-194 620.0
PYH3_k127_868989_3 Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008356 425.0
PYH3_k127_868989_4 Sigma-54 interaction domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 414.0
PYH3_k127_868989_5 Rhodanese Homology Domain - - - 0.0000000000000000000000000000000000000000000000000000000000003366 213.0
PYH3_k127_8705567_0 COG1123 ATPase components of various ABC-type transport systems, contain duplicated ATPase K02031,K02032 - - 5.144e-225 725.0
PYH3_k127_8705567_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000072 430.0
PYH3_k127_8705567_2 extracellular solute-binding protein, family 5 K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007336 429.0
PYH3_k127_8705567_3 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001096 304.0
PYH3_k127_8726849_0 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 377.0
PYH3_k127_8726849_1 Sigma-54 interaction domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001123 289.0
PYH3_k127_8726849_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005217 264.0
PYH3_k127_8726849_3 ABC transporter K02065 - - 0.000000000000000000000000000000000000000000000000000001531 200.0
PYH3_k127_873837_0 PFAM Acyl-CoA dehydrogenase K00249 - 1.3.8.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005293 475.0
PYH3_k127_873837_1 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000382 299.0
PYH3_k127_8744067_0 membrane-bound lytic murein transglycosylase K08304 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 389.0
PYH3_k127_8744067_1 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03981 - 5.3.4.1 0.00000000000000000000000000000000000000000000000000000009496 203.0
PYH3_k127_8744067_2 Ubiquinone biosynthesis - - - 0.0000000000000000009883 88.0
PYH3_k127_8748056_0 Arylsulfatase K01130,K01138 - 3.1.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003326 478.0
PYH3_k127_8748056_1 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007493 342.0
PYH3_k127_8748056_2 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005904 261.0
PYH3_k127_8748056_3 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.00000000000000000000000000000000000000000000000001723 186.0
PYH3_k127_8748056_4 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000852 175.0
PYH3_k127_8748056_5 regulation of ryanodine-sensitive calcium-release channel activity - - - 0.0000000000000000000000000000000000007418 149.0
PYH3_k127_8748056_7 methyltransferase activity - - - 0.0003092 49.0
PYH3_k127_8761468_0 ABC-type dipeptide transport system, periplasmic component K02035 - - 2.38e-235 738.0
PYH3_k127_8761468_1 Belongs to the ABC transporter superfamily K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 499.0
PYH3_k127_8761468_2 Metal-dependent amidase aminoacylase carboxypeptidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003126 490.0
PYH3_k127_8761468_3 Binding-protein-dependent transport system inner membrane component - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000142 466.0
PYH3_k127_8761468_4 ABC-type dipeptide oligopeptide nickel transport systems, permease components K02034 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002176 449.0
PYH3_k127_8761468_5 Oligopeptide/dipeptide transporter, C-terminal region K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 415.0
PYH3_k127_8761468_6 a g-specific adenine glycosylase K03575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002437 353.0
PYH3_k127_8782354_0 AMP-binding enzyme C-terminal domain K00666,K01897 - 6.2.1.3 8.885e-213 684.0
PYH3_k127_8782354_1 Phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 505.0
PYH3_k127_8782354_2 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K01781,K20023 - 4.2.1.156,4.2.1.42,5.1.2.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001416 413.0
PYH3_k127_8782354_3 phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002227 289.0
PYH3_k127_8782354_4 Copper chaperone PCu(A)C K09796 - - 0.000000000000000000000000001976 130.0
PYH3_k127_8782354_5 PFAM CoA-transferase family III K01796 - 5.1.99.4 0.0002031 44.0
PYH3_k127_8783355_0 (ABC) transporter K11004,K13409 - - 1.456e-213 677.0
PYH3_k127_8785745_0 Molybdopterin oxidoreductase Fe4S4 domain K21307 - 1.8.5.6 0.0 1079.0
PYH3_k127_8785745_1 Methyl-viologen-reducing hydrogenase, delta subunit K16886 - - 0.0 1058.0
PYH3_k127_8785745_2 PFAM Malic enzyme, NAD binding domain K00029 - 1.1.1.40 9.91e-212 668.0
PYH3_k127_8785745_3 HI0933-like protein - - - 1.435e-209 657.0
PYH3_k127_8785745_4 Cysteine-rich domain K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001897 464.0
PYH3_k127_8785745_5 4Fe-4S dicluster domain K16887 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006957 310.0
PYH3_k127_8786899_0 3-hydroxyacyl-coa dehydrogenase K07516 - 1.1.1.35 5.763e-274 859.0
PYH3_k127_8786899_1 Aldehyde dehydrogenase K00128,K00130 - 1.2.1.3,1.2.1.8 4.174e-215 678.0
PYH3_k127_8786899_10 Branched-chain amino acid ATP-binding cassette transporter K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 372.0
PYH3_k127_8786899_11 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002046 351.0
PYH3_k127_8786899_12 leucine import across plasma membrane K01997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001701 292.0
PYH3_k127_8786899_13 COG0410 ABC-type branched-chain amino acid transport systems, ATPase component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002994 286.0
PYH3_k127_8786899_14 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008014 285.0
PYH3_k127_8786899_15 EamA-like transporter family - - - 0.000000000000000000000000000000000000000000000001138 179.0
PYH3_k127_8786899_2 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 4.728e-213 694.0
PYH3_k127_8786899_3 Belongs to the thiolase family K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006989 550.0
PYH3_k127_8786899_4 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 508.0
PYH3_k127_8786899_5 Alanine dehydrogenase/PNT, N-terminal domain K00259 - 1.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000012 541.0
PYH3_k127_8786899_6 Psort location Cytoplasmic, score 7.50 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 511.0
PYH3_k127_8786899_7 Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily K00001,K00121 - 1.1.1.1,1.1.1.284 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005978 485.0
PYH3_k127_8786899_8 Periplasmic binding protein domain K01999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003207 384.0
PYH3_k127_8786899_9 Branched-chain amino acid transport system / permease component K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008221 393.0
PYH3_k127_8795085_0 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0000183,GO:0001302,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006139,GO:0006325,GO:0006342,GO:0006348,GO:0006355,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006996,GO:0007568,GO:0007569,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016458,GO:0016874,GO:0016879,GO:0018130,GO:0019219,GO:0019222,GO:0019357,GO:0019358,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0032502,GO:0034641,GO:0034654,GO:0040029,GO:0043094,GO:0043173,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0045814,GO:0045892,GO:0045934,GO:0046483,GO:0046497,GO:0048519,GO:0048523,GO:0048869,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051186,GO:0051188,GO:0051252,GO:0051253,GO:0051276,GO:0055086,GO:0060255,GO:0065007,GO:0071704,GO:0071840,GO:0072524,GO:0072525,GO:0080090,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902679,GO:1903506,GO:1903507,GO:2000112,GO:2000113,GO:2001141 6.3.4.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 581.0
PYH3_k127_8795085_1 COG2114 Adenylate cyclase, family 3 (some proteins contain HAMP domain) K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000385 286.0
PYH3_k127_8795085_10 (Hpt) domain - - - 0.000000000000000003832 87.0
PYH3_k127_8795085_2 LexA DNA binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002754 262.0
PYH3_k127_8795085_3 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004356 268.0
PYH3_k127_8795085_4 PFAM Metal-dependent phosphohydrolase, HD - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004723 264.0
PYH3_k127_8795085_5 SOS response associated peptidase (SRAP) - - - 0.000000000000000000000000000000000000000000000000000000000000001306 224.0
PYH3_k127_8795085_6 serine threonine protein kinase K11912 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000007641 208.0
PYH3_k127_8795085_7 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000002852 198.0
PYH3_k127_8795085_8 DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase K14162 - 2.7.7.7 0.0000000000000000000000000000000000000008748 150.0
PYH3_k127_8795085_9 cheY-homologous receiver domain - - - 0.00000000000000000000000000000003844 129.0
PYH3_k127_8812194_0 RmlD substrate binding domain K08679 - 5.1.3.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 422.0
PYH3_k127_8812194_1 COG1538 Outer membrane protein K12340 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 402.0
PYH3_k127_8812194_2 3-Deoxy-D-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 396.0
PYH3_k127_8812194_3 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005683 335.0
PYH3_k127_8812194_4 Glycosyltransferase family 9 (heptosyltransferase) K02841 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001103 316.0
PYH3_k127_8812194_5 Ribosomal RNA adenine dimethylase K00573 - 2.1.1.77 0.0000000000000000000000000000000000000000000000000000000000000000000000000002671 261.0
PYH3_k127_8812194_6 Hemolysin-type calcium-binding - - - 0.0000000000000000000000000000000000000000000000000000000000001467 244.0
PYH3_k127_8812194_7 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 0.000000000000000000000000000000000000000000001453 169.0
PYH3_k127_8886214_0 Crp-like helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 302.0
PYH3_k127_8886214_1 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000006598 217.0
PYH3_k127_8886214_2 PFAM DoxX family protein K15977 - - 0.0000000000000000000000000000000000000000002994 161.0
PYH3_k127_889367_0 FAD dependent oxidoreductase - - - 1.114e-237 746.0
PYH3_k127_889367_1 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003973 329.0
PYH3_k127_889367_2 PFAM MmgE PrpD family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000001556 239.0
PYH3_k127_889367_3 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000000000000000001802 108.0
PYH3_k127_8908838_0 Radical SAM K04069 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002229 597.0
PYH3_k127_8908838_1 Memo-like protein K06990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001385 424.0
PYH3_k127_8908838_2 Histidine kinase-like ATPases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007358 353.0
PYH3_k127_8908838_3 helix_turn_helix, Lux Regulon - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005396 252.0
PYH3_k127_8908838_4 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000000000000003115 181.0
PYH3_k127_8908838_5 Belongs to the CinA family K03743 - 3.5.1.42 0.00000000000000000000000000000000000000000000000989 176.0
PYH3_k127_8908838_6 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000004286 147.0
PYH3_k127_8921744_0 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009398 376.0
PYH3_k127_8921744_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001006 310.0
PYH3_k127_8950843_0 SMART Tetratricopeptide domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005162 451.0
PYH3_k127_8950843_1 Plays a critical role in the incorporation of lipoproteins in the outer membrane after they are released by the LolA protein K02494 - - 0.00000000000000003658 96.0
PYH3_k127_8960457_0 Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2) K00163 GO:0000287,GO:0003674,GO:0003824,GO:0004738,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0016491,GO:0016903,GO:0019842,GO:0030976,GO:0036094,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0043169,GO:0046872,GO:0046983,GO:0048037,GO:0050662,GO:0055114,GO:0097159,GO:1901363,GO:1901681 1.2.4.1 0.0 1028.0
PYH3_k127_8960457_1 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007826 318.0
PYH3_k127_90105_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 1.28e-283 886.0
PYH3_k127_90105_1 PFAM TRAP C4-dicarboxylate transport system permease DctM subunit - - - 1.32e-229 717.0
PYH3_k127_90105_10 ABC transporter transmembrane region K11004 - - 0.000000001796 62.0
PYH3_k127_90105_11 Histidine kinase K14986 - 2.7.13.3 0.0000004876 61.0
PYH3_k127_90105_2 Receptor family ligand binding region K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002964 559.0
PYH3_k127_90105_3 Bacterial extracellular solute-binding protein, family 7 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 556.0
PYH3_k127_90105_4 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006539 434.0
PYH3_k127_90105_5 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004327 420.0
PYH3_k127_90105_6 Branched-chain amino acid ATP-binding cassette transporter K01995,K01996 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000572 374.0
PYH3_k127_90105_7 ATPases associated with a variety of cellular activities K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001443 331.0
PYH3_k127_90105_8 Tripartite ATP-independent periplasmic transporters, DctQ component - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002026 266.0
PYH3_k127_90105_9 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000009562 102.0
PYH3_k127_9012679_0 Cupin domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001557 458.0
PYH3_k127_9012679_1 esterase K01432 - 3.5.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006566 298.0
PYH3_k127_9012679_2 Transglutaminase-like superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002361 258.0
PYH3_k127_9012679_3 Pyruvate ferredoxin/flavodoxin oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000001174 238.0
PYH3_k127_9012679_4 MOFRL family - - - 0.00000000000000000006548 91.0
PYH3_k127_9016807_0 GXGXG motif K00265,K00284 - 1.4.1.13,1.4.1.14,1.4.7.1 0.0 2350.0
PYH3_k127_9016807_1 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296,K18138 - - 0.0 1287.0
PYH3_k127_9016807_10 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000008489 218.0
PYH3_k127_9016807_11 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.0000000000000000000000000000000000000000000000000000000001662 207.0
PYH3_k127_9016807_12 fimbrial biogenesis protein PilN K02663 - - 0.000000000000000000000000000000000000000000000000000000004603 209.0
PYH3_k127_9016807_13 Inorganic ion transport and metabolism K06202 - - 0.00000000000000000000000000000526 131.0
PYH3_k127_9016807_14 pilus assembly protein pilp K02665 - - 0.000000000000000000000002662 111.0
PYH3_k127_9016807_2 penicillin-binding protein 1A K05366 - 2.4.1.129,3.4.16.4 5e-324 1007.0
PYH3_k127_9016807_3 Type 4 fimbrial biogenesis protein K02666 - - 9.287e-245 778.0
PYH3_k127_9016807_4 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 503.0
PYH3_k127_9016807_5 Pilus assembly protein K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002254 478.0
PYH3_k127_9016807_6 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007243 433.0
PYH3_k127_9016807_7 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07799 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001327 331.0
PYH3_k127_9016807_8 provides electrons to the alpha subunit, which binds L-glutamine and 2-oxoglutarate and forms L-glutamate K00266 - 1.4.1.13,1.4.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006828 301.0
PYH3_k127_9016807_9 Pilus assembly protein PilO K02664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000009175 245.0
PYH3_k127_9020418_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 - 6.1.1.20 4.219e-298 947.0
PYH3_k127_9020418_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004979 479.0
PYH3_k127_9020418_2 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K04764 - - 0.0000000000000000000000000000000000000000000000008543 175.0
PYH3_k127_9020418_3 PFAM regulatory protein MerR - - - 0.000000000000000000000000000000000000000000000001373 180.0
PYH3_k127_9021156_0 CoA binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 387.0
PYH3_k127_9021156_1 N-terminal half of MaoC dehydratase - - - 0.0000000000000000000000000000000000000000000000000001218 192.0
PYH3_k127_9021156_2 Iron-containing alcohol dehydrogenase - - - 0.00000001502 58.0
PYH3_k127_9032671_0 Sulfatase K01130 - 3.1.6.1 4.522e-271 844.0
PYH3_k127_9032671_1 Poly-beta-hydroxybutyrate K03821 - - 1.304e-243 765.0
PYH3_k127_9032671_10 ABC transporter substrate binding protein K01989 - - 0.0000000000000000000000000000000000000005081 161.0
PYH3_k127_9032671_11 Universal stress protein - - - 0.00000000000000000000000000000000000001768 148.0
PYH3_k127_9032671_12 - - - - 0.00000000000000000000000000000000001626 137.0
PYH3_k127_9032671_13 GYD domain - - - 0.00000000000000000000000000001575 120.0
PYH3_k127_9032671_14 protein conserved in bacteria - - - 0.000000000000000000000002697 109.0
PYH3_k127_9032671_15 Lipocalin-like domain - - - 0.000000000000000000000532 101.0
PYH3_k127_9032671_17 MSP (Major sperm protein) domain K15502,K15503 GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0031974,GO:0031981,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0070013 - 0.0001857 44.0
PYH3_k127_9032671_2 benzoyl-CoA oxygenase K15512 - 1.14.13.208 3.396e-205 643.0
PYH3_k127_9032671_3 Serine aminopeptidase, S33 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007529 480.0
PYH3_k127_9032671_4 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 469.0
PYH3_k127_9032671_5 alpha/beta hydrolase fold K00641 - 2.3.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004905 443.0
PYH3_k127_9032671_6 cysteine dioxygenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005334 258.0
PYH3_k127_9032671_7 EamA-like transporter family - - - 0.00000000000000000000000000000000000000000000000000000000000000001697 236.0
PYH3_k127_9032671_8 Rubrerythrin - - - 0.000000000000000000000000000000000000000000000000000007603 199.0
PYH3_k127_9032671_9 ABC transporter substrate binding protein K01989 - - 0.00000000000000000000000000000000000000000000000000001747 201.0
PYH3_k127_9057277_0 PFAM extracellular solute-binding protein, family 5 K02035 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 570.0
PYH3_k127_9057277_1 Involved in peptidolytic degradation of cyclic heptapeptide hepatotoxin microcystin (MC) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000006009 243.0
PYH3_k127_9057277_2 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000001443 198.0
PYH3_k127_9058294_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 3.934e-292 905.0
PYH3_k127_9058294_1 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008213 553.0
PYH3_k127_9058294_2 Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane K19804 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004189 269.0
PYH3_k127_9058294_3 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000001403 250.0
PYH3_k127_9058294_4 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 - 2.7.4.25 0.0000000000000000000000000000000000000000000000000000000000000000000001391 246.0
PYH3_k127_9058294_5 This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control K05788 - - 0.00000000000000000000000000000000000000000000001401 172.0
PYH3_k127_9058294_6 Lipopolysaccharide assembly protein A domain K08992 - - 0.00000000000000000003814 93.0
PYH3_k127_9087818_0 NAD(P)H-binding K01784 - 5.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002574 376.0
PYH3_k127_9087818_1 Polysaccharide biosynthesis protein - - - 0.00000000000000000000000000000000000000000000000000000004611 203.0
PYH3_k127_9087818_2 SBF-like CPA transporter family (DUF4137) K03453 - - 0.0000000000000000003 87.0
PYH3_k127_9114506_0 Rhodanese Homology Domain K06917 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000011 402.0
PYH3_k127_9114506_1 PFAM histone deacetylase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004134 264.0
PYH3_k127_9122570_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 2.41e-300 934.0
PYH3_k127_9122570_1 Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP), the rate-limiting step in the metabolic pathway that produces glucose from lactate and other precursors derived from the citric acid cycle K01596 GO:0000003,GO:0001655,GO:0001822,GO:0001889,GO:0003006,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003824,GO:0004457,GO:0004611,GO:0004613,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0005759,GO:0005975,GO:0005996,GO:0006006,GO:0006007,GO:0006066,GO:0006071,GO:0006082,GO:0006089,GO:0006090,GO:0006091,GO:0006094,GO:0006109,GO:0006111,GO:0006113,GO:0006139,GO:0006163,GO:0006464,GO:0006629,GO:0006631,GO:0006725,GO:0006732,GO:0006733,GO:0006734,GO:0006735,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0007028,GO:0007275,GO:0007276,GO:0007281,GO:0007292,GO:0007296,GO:0007610,GO:0008150,GO:0008152,GO:0008906,GO:0009056,GO:0009058,GO:0009062,GO:0009117,GO:0009123,GO:0009126,GO:0009132,GO:0009135,GO:0009141,GO:0009144,GO:0009150,GO:0009161,GO:0009166,GO:0009167,GO:0009179,GO:0009185,GO:0009199,GO:0009205,GO:0009259,GO:0009410,GO:0009605,GO:0009636,GO:0009653,GO:0009719,GO:0009725,GO:0009790,GO:0009792,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009967,GO:0009987,GO:0009991,GO:0010033,GO:0010243,GO:0010646,GO:0010647,GO:0010675,GO:0010906,GO:0014070,GO:0014074,GO:0015036,GO:0015980,GO:0016042,GO:0016043,GO:0016051,GO:0016052,GO:0016053,GO:0016054,GO:0016301,GO:0016310,GO:0016491,GO:0016614,GO:0016651,GO:0016667,GO:0016668,GO:0016740,GO:0016772,GO:0016773,GO:0016829,GO:0016830,GO:0016831,GO:0016999,GO:0017001,GO:0017144,GO:0018130,GO:0018991,GO:0019098,GO:0019222,GO:0019249,GO:0019318,GO:0019319,GO:0019320,GO:0019362,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019516,GO:0019538,GO:0019541,GO:0019543,GO:0019563,GO:0019626,GO:0019637,GO:0019659,GO:0019660,GO:0019661,GO:0019666,GO:0019674,GO:0019693,GO:0019751,GO:0019752,GO:0019953,GO:0022412,GO:0022414,GO:0023051,GO:0023056,GO:0030145,GO:0030154,GO:0030703,GO:0030855,GO:0031323,GO:0031667,GO:0031960,GO:0031974,GO:0032501,GO:0032502,GO:0032504,GO:0032787,GO:0032868,GO:0032869,GO:0032870,GO:0033993,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0035690,GO:0036211,GO:0042221,GO:0042493,GO:0042594,GO:0042737,GO:0043167,GO:0043169,GO:0043170,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0043255,GO:0043412,GO:0043434,GO:0043436,GO:0043687,GO:0043900,GO:0043903,GO:0043949,GO:0043950,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044249,GO:0044255,GO:0044260,GO:0044262,GO:0044267,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044422,GO:0044424,GO:0044429,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0045471,GO:0046031,GO:0046034,GO:0046164,GO:0046174,GO:0046364,GO:0046365,GO:0046394,GO:0046395,GO:0046434,GO:0046459,GO:0046483,GO:0046496,GO:0046677,GO:0046683,GO:0046700,GO:0046872,GO:0046914,GO:0047134,GO:0048468,GO:0048477,GO:0048513,GO:0048518,GO:0048522,GO:0048545,GO:0048562,GO:0048568,GO:0048583,GO:0048584,GO:0048598,GO:0048609,GO:0048646,GO:0048731,GO:0048732,GO:0048856,GO:0048869,GO:0050789,GO:0050792,GO:0050794,GO:0050896,GO:0051186,GO:0051384,GO:0051591,GO:0051704,GO:0051716,GO:0055086,GO:0055114,GO:0060429,GO:0061005,GO:0061008,GO:0062012,GO:0065007,GO:0070013,GO:0070365,GO:0070887,GO:0071236,GO:0071310,GO:0071361,GO:0071375,GO:0071383,GO:0071384,GO:0071385,GO:0071396,GO:0071407,GO:0071417,GO:0071466,GO:0071495,GO:0071548,GO:0071549,GO:0071704,GO:0071840,GO:0072001,GO:0072071,GO:0072329,GO:0072330,GO:0072521,GO:0072524,GO:0080090,GO:0097159,GO:0097237,GO:0097305,GO:0097306,GO:0097327,GO:1901135,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901363,GO:1901564,GO:1901575,GO:1901576,GO:1901615,GO:1901616,GO:1901617,GO:1901652,GO:1901653,GO:1901654,GO:1901655,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902531,GO:1902533 4.1.1.32 3.101e-296 918.0
PYH3_k127_9122570_10 rRNA small subunit methyltransferase G K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000006419 212.0
PYH3_k127_9122570_11 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02109 - - 0.0000000000000000000000000000000000000000000000004236 180.0
PYH3_k127_9122570_12 Major facilitator superfamily - - - 0.00000000000000000000000000000000000000000000006601 184.0
PYH3_k127_9122570_13 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.00000000000000000000000000000000000003036 156.0
PYH3_k127_9122570_14 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.00000000000000000000000000000000000007629 143.0
PYH3_k127_9122570_15 ATP synthase I chain K02116 - - 0.000000000000000003197 93.0
PYH3_k127_9122570_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 3.096e-281 869.0
PYH3_k127_9122570_3 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family - - - 1.534e-199 630.0
PYH3_k127_9122570_4 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002243 565.0
PYH3_k127_9122570_5 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003462 477.0
PYH3_k127_9122570_6 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009746 415.0
PYH3_k127_9122570_7 PFAM Cobyrinic acid a,c-diamide synthase K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004519 368.0
PYH3_k127_9122570_8 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 335.0
PYH3_k127_9122570_9 Pfam:AmoA K07120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001087 276.0
PYH3_k127_9146133_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003068 392.0
PYH3_k127_9146133_1 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 371.0
PYH3_k127_9151104_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002834 432.0
PYH3_k127_9151104_1 Possible lysine decarboxylase K06966 - 3.2.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004587 366.0
PYH3_k127_9151104_2 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001508 356.0
PYH3_k127_9151104_3 KR domain K00065 - 1.1.1.127 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002083 357.0
PYH3_k127_9151104_4 Uncharacterised ACR, YagE family COG1723 - - - 0.00000000000000000000000000000000000000000000000000000000000114 219.0
PYH3_k127_9151104_5 COG0204 1-acyl-sn-glycerol-3-phosphate acyltransferase - - - 0.00000000001482 66.0
PYH3_k127_9151104_6 Tripartite tricarboxylate transporter family receptor - - - 0.00003241 48.0
PYH3_k127_9152745_0 Lipase (class 2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 529.0
PYH3_k127_9152745_1 PFAM Gamma-glutamyltranspeptidase K00681 - 2.3.2.2,3.4.19.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001046 368.0
PYH3_k127_9152745_2 Bacterial transcriptional activator domain - - - 0.00000000000000000000000000000000000000000000000000000000000000001177 238.0
PYH3_k127_9152745_3 PFAM GCN5-related N-acetyltransferase - - - 0.00000000000000000000000000000000000000000000002322 180.0
PYH3_k127_9152745_4 - - - - 0.00000000000000000000000117 109.0
PYH3_k127_9152745_5 Mitochondrial biogenesis AIM24 - - - 0.000002829 53.0
PYH3_k127_9153694_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 - - 4e-323 1009.0
PYH3_k127_9153694_1 [2Fe-2S] binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000006932 222.0
PYH3_k127_9153694_2 Protein of unknown function (DUF1499) - - - 0.000000000000000000000000000000000000000005635 163.0
PYH3_k127_9153694_3 Domain of unknown function (DUF4136) - - - 0.0000002883 58.0
PYH3_k127_9217455_0 oxidoreductase FAD NAD(P)-binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001955 299.0
PYH3_k127_9217455_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001027 311.0
PYH3_k127_9217455_2 Bacterial protein of unknown function (DUF883) - - - 0.00000000000000000003596 94.0
PYH3_k127_9217455_3 Malic enzyme, NAD binding domain K00029 - 1.1.1.40 0.000000000004931 67.0
PYH3_k127_9220836_0 twitching motility protein K02670 - - 1.22e-202 638.0
PYH3_k127_9220836_1 twitching motility protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006664 619.0
PYH3_k127_9220836_2 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005213 278.0
PYH3_k127_9220836_3 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.0000000000000000000000000001256 124.0
PYH3_k127_9220836_4 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000002388 112.0
PYH3_k127_9276726_0 LytB protein K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001422 467.0
PYH3_k127_9276726_1 Zinc finger found in FPG and IleRS K01870 - 6.1.1.5 0.000000000000000000000000000000000000000000000002108 177.0
PYH3_k127_9276726_2 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.00000000000000000000000000000000000000000000006996 174.0
PYH3_k127_9296971_0 D-ala D-ala ligase N-terminus K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 393.0
PYH3_k127_9296971_1 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006231 286.0
PYH3_k127_9314404_0 NADH:flavin oxidoreductase / NADH oxidase family - - - 0.0 1071.0
PYH3_k127_9314404_1 AMP-binding enzyme C-terminal domain - - - 2.573e-218 690.0
PYH3_k127_9314404_2 phosphate K00625,K00634 - 2.3.1.19,2.3.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001681 274.0
PYH3_k127_9314404_3 Endoribonuclease L-PSP - - - 0.0000000000000000000000000000000000000005048 153.0
PYH3_k127_9314404_4 Hydantoinase B/oxoprolinase K01474 - 3.5.2.14 0.0000000000000000000000000000000000000005587 151.0
PYH3_k127_9314404_5 protein, possibly involved in aromatic compounds catabolism K02614 - - 0.0000000000000000000000000000002899 132.0
PYH3_k127_9314404_6 - - - - 0.0000000000003078 78.0
PYH3_k127_932605_0 Adenylate and Guanylate cyclase catalytic domain - - - 0.0 1080.0
PYH3_k127_932605_1 Adenylate and Guanylate cyclase catalytic domain - - - 2.151e-276 888.0
PYH3_k127_932605_2 Involved in the biosynthesis of porphyrin-containing compound - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003747 467.0
PYH3_k127_932605_3 serine threonine protein kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002431 385.0
PYH3_k127_932605_4 Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates K00989 - 2.7.7.56 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001917 353.0
PYH3_k127_932605_5 COG0631 Serine threonine protein phosphatase K20074 - 3.1.3.16 0.000000000000000000000000000000000000000000000000000000000000000000000000004576 262.0
PYH3_k127_932605_6 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 - 3.6.1.66 0.00000000000000000000000000000000000000000000000000000000000000000000001179 258.0
PYH3_k127_932605_7 Domain of unknown function (DUF1732) - - - 0.0000000000000148 86.0
PYH3_k127_9330475_0 protein-(glutamine-N5) methyltransferase activity K21786 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003911 378.0
PYH3_k127_9330475_1 Permeases of the major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000009084 204.0
PYH3_k127_9333050_0 The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane K00324 - 1.6.1.2 2.078e-239 746.0
PYH3_k127_9333050_1 Substrate binding domain of ABC-type glycine betaine transport system K05845,K05846 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005746 537.0
PYH3_k127_9333050_2 COG1132 ABC-type multidrug transport system, ATPase and permease components K06147 - - 0.0000000000000000000000000000000001106 134.0
PYH3_k127_9336908_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 5.301e-253 793.0
PYH3_k127_9336908_1 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008237 533.0
PYH3_k127_9336908_2 Peptidase family M28 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005516 323.0
PYH3_k127_9336908_3 Protein of unknown function DUF99 K09120 - - 0.0000000000000000000000000000000000000000000000001413 180.0
PYH3_k127_9336908_4 PFAM CBS domain containing protein - - - 0.00000000000000000000000000000000000004214 149.0
PYH3_k127_9336908_5 - - - - 0.00000000000000000000000002582 114.0
PYH3_k127_9336908_6 - - - - 0.0000000000000000000001149 102.0
PYH3_k127_9336908_7 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000002884 50.0
PYH3_k127_9339704_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 0.0 1352.0
PYH3_k127_9339704_1 Molecular chaperone. Has ATPase activity K04079 - - 3.612e-287 893.0
PYH3_k127_9339704_10 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002006 390.0
PYH3_k127_9339704_11 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001261 398.0
PYH3_k127_9339704_12 Na+-dependent bicarbonate transporter superfamily K07086 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000126 343.0
PYH3_k127_9339704_13 Transcriptional regulator K21703 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006285 284.0
PYH3_k127_9339704_14 Enoyl-CoA hydratase - - - 0.0000000000000000000000000000000000000000000000000000000000003013 220.0
PYH3_k127_9339704_15 Bacterial transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000003165 217.0
PYH3_k127_9339704_16 Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division - - - 0.000000000000000000000000000000000000000000000000000000000004311 217.0
PYH3_k127_9339704_17 Belongs to the BI1 family K19416 - - 0.00000000000000000000000000000000000000000000000000000000004623 215.0
PYH3_k127_9339704_18 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0000000000000000000000000000000000000000000000000000004254 197.0
PYH3_k127_9339704_19 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000006867 194.0
PYH3_k127_9339704_2 Methylmalonyl-CoA mutase K01848,K14447,K20906 - 5.4.99.2,5.4.99.63,5.4.99.64 6.602e-243 780.0
PYH3_k127_9339704_20 Belongs to the ompA family K03640 - - 0.000000000000000000000000000000000000000000000002238 193.0
PYH3_k127_9339704_21 Bacterial regulatory proteins, tetR family - - - 0.000000000000000000000000000000000000000000000006227 180.0
PYH3_k127_9339704_22 response to cobalt ion - - - 0.0000000000000000000000000000000000000000000002585 174.0
PYH3_k127_9339704_23 Methylmalonyl-CoA mutase K14447 - 5.4.99.63 0.00000000000000000000000000000000000000000005915 170.0
PYH3_k127_9339704_24 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.0000000000000000000000000000000000000006406 151.0
PYH3_k127_9339704_25 TspO MBR family protein K05770 - - 0.00000000000000000000000000000000006926 141.0
PYH3_k127_9339704_26 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000008063 117.0
PYH3_k127_9339704_27 Protein of unknown function (DUF805) - - - 0.0000000000000000000000000003573 118.0
PYH3_k127_9339704_28 - - - - 0.00000000000000000000000003212 109.0
PYH3_k127_9339704_29 Belongs to the P(II) protein family - - - 0.000000000000001986 89.0
PYH3_k127_9339704_3 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005208 609.0
PYH3_k127_9339704_30 Transglycosylase associated protein - - - 0.0000000009938 63.0
PYH3_k127_9339704_31 Murein-degrading enzyme that degrades murein glycan strands and insoluble, high-molecular weight murein sacculi, with the concomitant formation of a 1,6-anhydromuramoyl product. Lytic transglycosylases (LTs) play an integral role in the metabolism of the peptidoglycan (PG) sacculus. Their lytic action creates space within the PG sacculus to allow for its expansion as well as for the insertion of various structures such as secretion systems and flagella - - - 0.00000003611 59.0
PYH3_k127_9339704_4 Involved in the tonB-independent uptake of proteins K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003571 529.0
PYH3_k127_9339704_5 PFAM fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008889 501.0
PYH3_k127_9339704_6 CoA-transferase family III - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002183 508.0
PYH3_k127_9339704_7 Sulphur transport K07112 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 471.0
PYH3_k127_9339704_8 Trypsin K04771,K04772 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009454 440.0
PYH3_k127_9339704_9 Integral membrane protein TerC family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007346 403.0
PYH3_k127_9342194_0 Histidine kinase K07673 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001602 303.0
PYH3_k127_9342194_1 response regulator K07684 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002564 271.0
PYH3_k127_9347979_0 cyclic 2,3-diphosphoglycerate synthetase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005813 401.0
PYH3_k127_9347979_1 AAA domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 375.0
PYH3_k127_9360819_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006505 343.0
PYH3_k127_9360819_1 Methionine biosynthesis protein MetW - - - 0.00000000000000000000000000000000000000000000000000001271 198.0
PYH3_k127_9360819_2 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000002083 165.0
PYH3_k127_9360819_3 6-phosphogluconate dehydrogenase K00033 - 1.1.1.343,1.1.1.44 0.0000007645 51.0
PYH3_k127_936991_0 Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster - - - 3.689e-314 975.0
PYH3_k127_936991_1 - - - - 0.00000000000000000000000001371 116.0
PYH3_k127_936991_2 Fe-S oxidoreductase K21834 - - 0.0000000000000002815 78.0
PYH3_k127_9374638_0 Aminotransferase K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 610.0
PYH3_k127_9374638_1 Acts as a magnesium transporter K06213 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002673 590.0
PYH3_k127_9374638_2 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.000000008217 56.0
PYH3_k127_9382202_0 Aldehyde dehydrogenase family K00140 - 1.2.1.18,1.2.1.27 6.06e-200 630.0
PYH3_k127_9382202_1 NMT1-like family K07080 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002207 264.0
PYH3_k127_9399663_0 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008938 512.0
PYH3_k127_9399663_1 type 4 pilus biogenesis protein K02656 - - 0.0000000000000000000000000000000000000000000000000000000000000000001401 239.0
PYH3_k127_9399663_2 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.000000000000000000000000000000000000000000000000000000000000000001098 230.0
PYH3_k127_9399663_3 Enoyl-CoA hydratase - - - 0.000000000000000000000000000000000000000000000000006023 187.0
PYH3_k127_9399663_4 Helix-turn-helix domain K15539 - - 0.00000000000004103 84.0
PYH3_k127_9405927_0 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 521.0
PYH3_k127_9405927_1 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007725 511.0
PYH3_k127_9405927_10 - - - - 0.0009522 42.0
PYH3_k127_9405927_2 Amidohydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003313 374.0
PYH3_k127_9405927_3 GHMP kinases N terminal domain K00919 - 2.7.1.148 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003373 327.0
PYH3_k127_9405927_4 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005864 250.0
PYH3_k127_9405927_5 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 - 3.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000518 232.0
PYH3_k127_9405927_6 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000379 186.0
PYH3_k127_9405927_7 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000004405 83.0
PYH3_k127_9405927_9 Outer membrane lipoprotein LolB - - - 0.00001476 48.0
PYH3_k127_9440538_0 Adenylyl cyclase class-3 4 guanylyl cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 369.0
PYH3_k127_9452262_0 Cys/Met metabolism PLP-dependent enzyme K01740 - 2.5.1.49 4.138e-213 670.0
PYH3_k127_9452262_1 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003676 582.0
PYH3_k127_9452262_10 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000001933 101.0
PYH3_k127_9452262_11 - - - - 0.00000000000000000000343 108.0
PYH3_k127_9452262_12 Protein of unknown function (DUF3567) - - - 0.00000000000000002949 83.0
PYH3_k127_9452262_13 PFAM type I phosphodiesterase nucleotide pyrophosphatase - - - 0.000000000001037 70.0
PYH3_k127_9452262_2 Radical SAM - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000281 453.0
PYH3_k127_9452262_3 PFAM multi antimicrobial extrusion protein MatE - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003701 392.0
PYH3_k127_9452262_4 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 361.0
PYH3_k127_9452262_5 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001025 279.0
PYH3_k127_9452262_6 - - - - 0.0000000000000000000000000000000000000000458 158.0
PYH3_k127_9452262_7 - - - - 0.00000000000000000000000000000000007857 140.0
PYH3_k127_9452262_8 DsrE/DsrF/DrsH-like family - - - 0.0000000000000000000000000000002177 128.0
PYH3_k127_9452262_9 Putative serine dehydratase domain K18425 - 4.1.3.41 0.00000000000000000000000000004552 132.0
PYH3_k127_9457897_0 DNA polymerase K02337 - 2.7.7.7 0.0 1163.0
PYH3_k127_9457897_1 AIR synthase related protein domain protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 485.0
PYH3_k127_9457897_2 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000003591 274.0
PYH3_k127_9457897_3 TIGRFAM DnaA regulatory inactivator Hda K10763 - - 0.00000000000000000000000000000000000000000000000003286 196.0
PYH3_k127_9457897_4 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000001895 153.0
PYH3_k127_9483469_0 HD domain K13815 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 420.0
PYH3_k127_9483469_1 Histidine Phosphotransfer domain K10715 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002209 380.0
PYH3_k127_9483469_2 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.000000000000000000000000000000000000000000000000000000000000000000001103 241.0
PYH3_k127_9493231_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1274.0
PYH3_k127_9493231_1 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K07798,K15727 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001439 321.0
PYH3_k127_9493231_2 Transcriptional regulatory protein, C terminal K02483 - - 0.000000000000000000000000000000000000000000000000000000000002762 236.0
PYH3_k127_9493231_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483,K07774 - - 0.00000000000000000000000000000000000000000000002322 180.0
PYH3_k127_9493231_4 PFAM Outer membrane efflux protein K15725 - - 0.000000000000000000000000000000000000000003143 161.0
PYH3_k127_9510588_0 Belongs to the metallo-dependent hydrolases superfamily. Urease alpha subunit family K01428 - 3.5.1.5 2.336e-313 970.0
PYH3_k127_9510588_1 Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG K03189 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000294 363.0
PYH3_k127_9510588_2 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03188 - - 0.0000000000000000000000000000000000000000000000000000000000002113 227.0
PYH3_k127_9510588_3 Required for maturation of urease via the functional incorporation of the urease nickel metallocenter K03190 - - 0.000000000000000000000000000000000000000000000000000000001398 206.0
PYH3_k127_9510588_4 Belongs to the urease gamma subunit family K01430 - 3.5.1.5 0.000000000000000000000000000000000000000000000001337 176.0
PYH3_k127_9510588_5 Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly K03187 - - 0.000000000000000000000000000000000000000000147 165.0
PYH3_k127_9510588_6 Fumarylacetoacetate (FAA) hydrolase family - - - 0.000000000000000000000000000000000000003092 162.0
PYH3_k127_9510588_7 Belongs to the urease beta subunit family K01429 - 3.5.1.5 0.00000000000000000000000000000000000002105 149.0
PYH3_k127_9510588_8 Trypsin-like peptidase domain - - - 0.0001147 45.0
PYH3_k127_9517455_0 alpha-L-arabinofuranosidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002659 473.0
PYH3_k127_9517455_1 EamA-like transporter family - - - 0.0000000000000000000000000000000000000000000000000000000000001426 224.0
PYH3_k127_9517455_2 Penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000000000000000000000000000009323 191.0
PYH3_k127_9517455_3 Domain of unknown function (DUF5122) beta-propeller - - - 0.0000000000003639 84.0
PYH3_k127_9525544_0 COG0643 Chemotaxis protein histidine kinase and related kinases K02487,K06596 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005645 389.0
PYH3_k127_9548872_0 Carboxyl transferase domain - - - 3.967e-211 667.0
PYH3_k127_9548872_1 PFAM ABC transporter related K01996 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 359.0
PYH3_k127_9548872_2 ABC transporter K01995 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006118 366.0
PYH3_k127_9548872_3 Belongs to the binding-protein-dependent transport system permease family K01995,K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003773 258.0
PYH3_k127_9548872_4 - - - - 0.0000000000000000000000000009166 130.0
PYH3_k127_9548872_5 EamA-like transporter family - - - 0.00007884 45.0
PYH3_k127_9585575_0 Belongs to the LDH2 MDH2 oxidoreductase family K00073,K13574 - 1.1.1.350 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 428.0
PYH3_k127_9585575_1 adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000001057 259.0
PYH3_k127_9585575_2 Tripartite tricarboxylate transporter family receptor - - - 0.0000000000517 64.0
PYH3_k127_9601084_0 Tripartite tricarboxylate transporter family receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 323.0
PYH3_k127_9601084_1 haloacid dehalogenase K01560 - 3.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000009755 295.0
PYH3_k127_9601084_2 Cobalamin adenosyltransferase K00798 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.5.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000005201 245.0
PYH3_k127_9601084_3 oxidation-reduction process - - - 0.0000000000000000000000000000000000000000000001894 178.0
PYH3_k127_9601084_4 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.00000000000000000000000000000000001848 139.0
PYH3_k127_9601084_5 Protein of unknown function (DUF541) - - - 0.000000000000000000000000000002643 130.0
PYH3_k127_9601084_6 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.000001657 51.0
PYH3_k127_9633782_0 Belongs to the binding-protein-dependent transport system permease family K01998 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007513 383.0
PYH3_k127_9633782_1 Belongs to the binding-protein-dependent transport system permease family K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001322 299.0
PYH3_k127_9633782_2 branched-chain amino acid transport K01995,K01998 - - 0.0000000000000000000000000000000000000000000000001819 199.0
PYH3_k127_9636652_0 NADH ubiquinone oxidoreductase, subunit G, iron-sulphur binding K00336 - 1.6.5.3 4.052e-258 811.0
PYH3_k127_9636652_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain K00335 - 1.6.5.3 3.482e-233 737.0
PYH3_k127_9636652_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 2.859e-232 736.0
PYH3_k127_9636652_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002187 326.0
PYH3_k127_9636652_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004806 311.0
PYH3_k127_9636652_5 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000001307 247.0
PYH3_k127_9681361_0 Belongs to the TPP enzyme family K01652 - 2.2.1.6 5.413e-241 758.0
PYH3_k127_9681361_1 Amidase K02433 - 6.3.5.6,6.3.5.7 1.557e-198 642.0
PYH3_k127_9681361_10 - - - - 0.000000000000000000000000000001103 133.0
PYH3_k127_9681361_11 PFAM AMP-dependent synthetase and ligase K00666,K01897 - 6.2.1.3 0.000000000000000005163 96.0
PYH3_k127_9681361_12 Allophanate hydrolase subunit 2 - - - 0.000000000000004899 86.0
PYH3_k127_9681361_2 COG1473 Metal-dependent amidase aminoacylase carboxypeptidase K01436 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003847 460.0
PYH3_k127_9681361_3 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000001575 278.0
PYH3_k127_9681361_4 Nitrile hydratase K01721,K20807 - 4.2.1.84 0.00000000000000000000000000000000000000000000000000000000000000000000000006986 255.0
PYH3_k127_9681361_5 Allophanate hydrolase subunit 1 - - - 0.00000000000000000000000000000000000000000000000009175 195.0
PYH3_k127_9681361_6 Glyoxalase-like domain - - - 0.0000000000000000000000000000000000000000001135 171.0
PYH3_k127_9681361_7 enzyme involved in biosynthesis of extracellular polysaccharides - - - 0.000000000000000000000000000000000000000006963 156.0
PYH3_k127_9681361_8 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.000000000000000000000000000000000001862 140.0
PYH3_k127_9681361_9 Nitrile hydratase beta subunit K20807 - 4.2.1.84 0.0000000000000000000000000000003735 134.0
PYH3_k127_9710582_0 Adds poly(A) tail to the 3' end of many RNAs, which usually targets these RNAs for decay. Plays a significant role in the global control of gene expression, through influencing the rate of transcript degradation, and in the general RNA quality control K00970 - 2.7.7.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006057 541.0
PYH3_k127_9710582_1 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000002156 169.0
PYH3_k127_9740378_0 PFAM peptidase M48 Ste24p - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 323.0
PYH3_k127_9740378_1 LemA family K03744 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000009914 270.0
PYH3_k127_9740378_2 Aldo keto - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002947 266.0
PYH3_k127_9740378_3 ATP ADP translocase K03301 - - 0.0000000000000000000000000000000000000000000000000000000001722 210.0
PYH3_k127_9745178_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 511.0
PYH3_k127_9745178_1 COG1788 Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit K01039 - 2.8.3.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002788 305.0
PYH3_k127_9771812_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 GO:0000162,GO:0003674,GO:0003824,GO:0004048,GO:0006082,GO:0006520,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046219,GO:0046394,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001934 458.0
PYH3_k127_9771812_1 PFAM Glutamine amidotransferase class-I K01658 - 4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003549 297.0
PYH3_k127_9771812_2 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001854 273.0
PYH3_k127_9787179_0 TIGRFAM filamentous haemagglutinin family outer membrane protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001655 276.0
PYH3_k127_9787179_1 Ribosomal protein L17 K02879 - - 0.0000000000000000000000000000000000000000000000000000001937 201.0
PYH3_k127_9787179_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000002985 152.0
PYH3_k127_9790642_0 Helicase associated domain (HA2) Add an annotation K03578 - 3.6.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002777 582.0
PYH3_k127_9790642_1 Cysteine rich repeat K06816 GO:0000137,GO:0000138,GO:0000139,GO:0001501,GO:0002376,GO:0003674,GO:0005102,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005795,GO:0005797,GO:0005886,GO:0006810,GO:0006886,GO:0006928,GO:0007275,GO:0008104,GO:0008150,GO:0009653,GO:0009887,GO:0009892,GO:0009966,GO:0009968,GO:0009987,GO:0010468,GO:0010605,GO:0010629,GO:0010646,GO:0010648,GO:0010955,GO:0012505,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0016477,GO:0017015,GO:0017134,GO:0019222,GO:0019838,GO:0023051,GO:0023057,GO:0030162,GO:0030512,GO:0031012,GO:0031090,GO:0031224,GO:0031323,GO:0031324,GO:0031984,GO:0031985,GO:0032268,GO:0032269,GO:0032330,GO:0032501,GO:0032502,GO:0033036,GO:0034613,GO:0040011,GO:0042886,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0045184,GO:0045595,GO:0045861,GO:0046907,GO:0048513,GO:0048519,GO:0048523,GO:0048583,GO:0048585,GO:0048705,GO:0048731,GO:0048856,GO:0048870,GO:0050789,GO:0050793,GO:0050794,GO:0050900,GO:0051171,GO:0051172,GO:0051179,GO:0051234,GO:0051239,GO:0051246,GO:0051248,GO:0051641,GO:0051649,GO:0051674,GO:0060255,GO:0060348,GO:0060349,GO:0061035,GO:0065007,GO:0070613,GO:0070727,GO:0071702,GO:0071705,GO:0071944,GO:0080090,GO:0090092,GO:0090101,GO:0090287,GO:0090288,GO:0098588,GO:0098791,GO:1903317,GO:1903318,GO:1903844,GO:1903845,GO:2000026 - 0.00000001409 63.0
PYH3_k127_9792182_0 DEAD DEAH box helicase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003938 493.0
PYH3_k127_9792182_1 PFAM MOSC domain - - - 0.0000000000000000000000000000000000000000001186 179.0
PYH3_k127_9793722_0 4Fe-4S dicluster domain - - - 0.0 1241.0
PYH3_k127_9793722_1 Belongs to the IlvD Edd family - - - 8.887e-284 884.0
PYH3_k127_9793722_10 Branched-chain amino acid transport system / permease component K01998 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000333 491.0
PYH3_k127_9793722_11 4Fe-4S ferredoxin iron-sulfur binding domain protein K21834 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001494 459.0
PYH3_k127_9793722_12 Receptor family ligand binding region K01999 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000583 450.0
PYH3_k127_9793722_13 Domain of unknown function (DUF4347) K21449 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 469.0
PYH3_k127_9793722_14 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000673 428.0
PYH3_k127_9793722_15 Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps K04084 - 1.8.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001406 422.0
PYH3_k127_9793722_16 Tripartite tricarboxylate transporter family receptor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 384.0
PYH3_k127_9793722_17 Branched-chain amino acid transport system / permease component K01997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 383.0
PYH3_k127_9793722_18 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002027 368.0
PYH3_k127_9793722_19 ABC-type branched-chain amino acid transport systems ATPase component K01995 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002181 374.0
PYH3_k127_9793722_2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 5.054e-271 841.0
PYH3_k127_9793722_20 Inner membrane protein involved in colicin E2 resistance K06143 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000066 367.0
PYH3_k127_9793722_21 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002064 364.0
PYH3_k127_9793722_22 Enoyl-CoA hydratase/isomerase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 340.0
PYH3_k127_9793722_23 Transcriptional regulatory protein, C terminal K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008041 325.0
PYH3_k127_9793722_24 membrane transporter protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005195 317.0
PYH3_k127_9793722_25 haloacid dehalogenase-like hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 310.0
PYH3_k127_9793722_26 PFAM NAD-dependent epimerase dehydratase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000467 306.0
PYH3_k127_9793722_27 AAA domain, putative AbiEii toxin, Type IV TA system K01996 - - 0.000000000000000000000000000000000000000000000000000000000000000000000102 248.0
PYH3_k127_9793722_28 FCD - - - 0.00000000000000000000000000000000000000000000000000000000000000000004535 238.0
PYH3_k127_9793722_29 Glutathione S-transferase K00799 - 2.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000976 236.0
PYH3_k127_9793722_3 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 1.824e-259 804.0
PYH3_k127_9793722_30 PFAM Bacterial protein of - - - 0.0000000000000000000000000000000000000000000000000000000000001738 218.0
PYH3_k127_9793722_31 nitrate reductase activity - - - 0.000000000000000000000000000000000000000000000000000000001934 207.0
PYH3_k127_9793722_32 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.0000000000000000000000000000000000000000000000000000008721 195.0
PYH3_k127_9793722_33 protein involved in tolerance to divalent cations K03926 - - 0.000000000000000000000000000000000002244 152.0
PYH3_k127_9793722_35 Q COG2931 RTX toxins and related Ca2 -binding proteins - - - 0.000000000000000000000113 115.0
PYH3_k127_9793722_36 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000002844 67.0
PYH3_k127_9793722_37 SMART Transport-associated and nodulation region K04065 - - 0.0000000001539 73.0
PYH3_k127_9793722_38 Histidine kinase - - - 0.0000008562 62.0
PYH3_k127_9793722_4 Protein of unknown function, DUF255 K06888 - - 6.286e-249 790.0
PYH3_k127_9793722_5 PFAM AMP-dependent synthetase and ligase - - - 5.595e-230 722.0
PYH3_k127_9793722_6 Aminotransferase class-V K00830 - 2.6.1.44,2.6.1.45,2.6.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009803 592.0
PYH3_k127_9793722_7 AMP-binding enzyme C-terminal domain K18661 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003743 590.0
PYH3_k127_9793722_8 Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family K00111 - 1.1.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008353 549.0
PYH3_k127_9793722_9 Oxidoreductase FAD-binding domain K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004444 483.0
PYH3_k127_987069_0 TIGRFAM formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 6.941e-309 956.0
PYH3_k127_987069_1 PFAM Respiratory-chain NADH dehydrogenase domain, 51 kDa subunit K00122 - 1.17.1.9 4.614e-246 769.0
PYH3_k127_987069_2 glutamine amidotransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 325.0
PYH3_k127_987069_3 Transcriptional regulator, Crp Fnr family K10914 GO:0000166,GO:0000976,GO:0001067,GO:0001130,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006109,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010565,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0010675,GO:0016020,GO:0017076,GO:0019219,GO:0019222,GO:0030312,GO:0030551,GO:0030552,GO:0030554,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0032993,GO:0036094,GO:0040007,GO:0043167,GO:0043168,GO:0043565,GO:0044212,GO:0044464,GO:0045892,GO:0045893,GO:0045934,GO:0045935,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0060255,GO:0062012,GO:0065007,GO:0071944,GO:0080090,GO:0097159,GO:0097367,GO:0140110,GO:1901265,GO:1901363,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2000874,GO:2001141 - 0.0000002343 60.0
PYH3_k127_993888_0 PFAM cell divisionFtsK SpoIIIE K03466 - - 3.926e-307 959.0
PYH3_k127_993888_1 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 5.189e-207 650.0
PYH3_k127_993888_10 receptor - - - 0.0001815 45.0
PYH3_k127_993888_2 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003872 507.0
PYH3_k127_993888_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003144 508.0
PYH3_k127_993888_4 Hemolysin activation secretion protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009369 419.0
PYH3_k127_993888_5 Nucleoside-binding outer membrane protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004895 340.0
PYH3_k127_993888_6 Transcriptional regulator crp fnr family K10914 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001168 260.0
PYH3_k127_993888_7 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) K03634 - - 0.0000000000000000000000000000000000000000000000000000000000006104 217.0
PYH3_k127_993888_8 FecR protein - - - 0.0000000000000000000000000000000000000000000000006857 183.0
PYH3_k127_993888_9 Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain K03520 - 1.2.5.3 0.000000000000000000000000000000000000000006485 159.0
PYH3_k127_994211_0 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003315 324.0
PYH3_k127_994211_1 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000158 247.0