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Overview

ID MAG03228
Name PYH3_bin.35
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Campylobacterota
Class Campylobacteria
Order Campylobacterales
Family Sulfurimonadaceae
Genus Sulfuricurvum
Species
Assembly information
Completeness (%) 65.21
Contamination (%) 2.52
GC content (%) 45.0
N50 (bp) 8,138
Genome size (bp) 1,362,554

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1449

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1012831_0 Ribonuclease K12573 - - 0.0 1085.0
PYH3_k127_1012831_1 DNA polymerase III K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001504 539.0
PYH3_k127_1012831_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009915 357.0
PYH3_k127_1012831_3 - - - - 0.0000000000000000000000000009672 113.0
PYH3_k127_1108819_0 Single-stranded-DNA-specific exonuclease (RecJ) K07462 - - 5.034e-275 852.0
PYH3_k127_1108819_1 pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 1.794e-233 729.0
PYH3_k127_1108819_2 tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 379.0
PYH3_k127_1108819_3 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.00000000000000000000002553 99.0
PYH3_k127_11762_0 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001635 341.0
PYH3_k127_11762_1 PFAM ABC transporter K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001971 272.0
PYH3_k127_11762_2 Chemotaxis protein CheW K03408 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002766 265.0
PYH3_k127_120969_0 Participates in both transcription termination and antitermination K02600 - - 8.654e-205 641.0
PYH3_k127_120969_1 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 533.0
PYH3_k127_120969_2 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003933 381.0
PYH3_k127_120969_3 - - - - 0.0000000000000000000000000000000000000003977 149.0
PYH3_k127_1231722_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003024 489.0
PYH3_k127_1231722_1 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003603 491.0
PYH3_k127_1231722_2 NMT1/THI5 like - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004936 394.0
PYH3_k127_1231722_3 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 321.0
PYH3_k127_1231722_4 Belongs to the ompA family K03286 - - 0.000000000000000000000000000000000004262 142.0
PYH3_k127_1260732_0 TamB, inner membrane protein subunit of TAM complex K09800 - - 2.507e-318 999.0
PYH3_k127_1260732_1 Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation K02232 - 6.3.5.10 6.818e-266 827.0
PYH3_k127_1260732_2 COG4775 Outer membrane protein protective antigen OMA87 K07278 - - 1.989e-238 749.0
PYH3_k127_1260732_3 Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate K02233 - 2.7.8.26 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 334.0
PYH3_k127_1260732_4 Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group K02227 - 6.3.1.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 328.0
PYH3_k127_1260732_5 Hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000002949 218.0
PYH3_k127_1260732_6 alpha-ribazole phosphatase activity K02226 - 3.1.3.73 0.000000000000000000000000000000000000000000000152 173.0
PYH3_k127_1286927_0 ATP synthase K02412 - 3.6.3.14 5.034e-247 768.0
PYH3_k127_1286927_1 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.678e-228 712.0
PYH3_k127_1286927_2 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002029 477.0
PYH3_k127_1286927_3 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004907 380.0
PYH3_k127_1286927_4 GTP cyclohydrolase K01495 - 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 350.0
PYH3_k127_1286927_5 Mg chelatase-related protein K07391 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007199 277.0
PYH3_k127_1286927_6 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000000275 264.0
PYH3_k127_13097_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K16881 - 2.7.7.13,5.4.2.8 6.106e-281 870.0
PYH3_k127_1407230_0 COG0507 ATP-dependent exoDNAse (exonuclease V) alpha subunit - helicase superfamily I member K03581 - 3.1.11.5 0.0 1135.0
PYH3_k127_1407230_1 K+ potassium transporter K03549 - - 4.55e-320 988.0
PYH3_k127_1407230_10 COGs COG3786 conserved - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001059 267.0
PYH3_k127_1407230_11 Membrane - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001513 247.0
PYH3_k127_1407230_12 Transcriptional regulator K15973 - - 0.0000000000000000000000000000000000000000000000000000000000000000000003291 240.0
PYH3_k127_1407230_13 ABC-type phosphate phosphonate transport system periplasmic component K02044 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004166 246.0
PYH3_k127_1407230_14 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000001527 217.0
PYH3_k127_1407230_15 Catalytic LigB subunit of aromatic ring-opening dioxygenase K15777 - - 0.000000000000000000000000000000000000001558 149.0
PYH3_k127_1407230_17 - - - - 0.0000000000000000000000001704 106.0
PYH3_k127_1407230_2 Cytochrome K00428 - 1.11.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009489 550.0
PYH3_k127_1407230_3 Histidine kinase A domain protein K10715 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004946 405.0
PYH3_k127_1407230_4 Amino acid permease K03294 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000435 370.0
PYH3_k127_1407230_5 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002071 371.0
PYH3_k127_1407230_6 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007717 329.0
PYH3_k127_1407230_7 Belongs to the UPF0312 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001783 318.0
PYH3_k127_1407230_8 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002293 304.0
PYH3_k127_1407230_9 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005242 305.0
PYH3_k127_141776_0 PAS fold - - - 0.0000000000000000000000000000000000000000000000000000000000000000003786 250.0
PYH3_k127_141776_1 PAS domain - - - 0.00000000000000000000000000000000000000000000000000000000000000004257 246.0
PYH3_k127_141776_2 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000001707 109.0
PYH3_k127_141776_3 response regulator K03413 - - 0.0000000000000000008076 101.0
PYH3_k127_142988_0 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 0.0 1139.0
PYH3_k127_142988_1 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15633 - 5.4.2.12 1.392e-268 832.0
PYH3_k127_142988_10 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 380.0
PYH3_k127_142988_11 HDOD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009532 361.0
PYH3_k127_142988_12 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000567 349.0
PYH3_k127_142988_13 Belongs to the TrpF family K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005051 319.0
PYH3_k127_142988_14 transformation system protein K02242 - - 0.000000000000000000000000000000000000000000001965 165.0
PYH3_k127_142988_15 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.00000000000000000000000000000000001366 136.0
PYH3_k127_142988_16 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.00000000000000000000000000001871 118.0
PYH3_k127_142988_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 1.202e-248 769.0
PYH3_k127_142988_3 Chemotaxis phosphatase CheX - - - 2.113e-236 737.0
PYH3_k127_142988_4 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 3.009e-222 693.0
PYH3_k127_142988_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 1.548e-201 630.0
PYH3_k127_142988_6 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003477 572.0
PYH3_k127_142988_7 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 571.0
PYH3_k127_142988_8 reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007626 432.0
PYH3_k127_142988_9 Belongs to the ribulose-phosphate 3-epimerase family K01783 - 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002865 414.0
PYH3_k127_1429958_0 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.0 1060.0
PYH3_k127_1429958_1 PFAM ATPase family associated with various cellular activities (AAA) K03924 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006337 522.0
PYH3_k127_1429958_2 protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003706 443.0
PYH3_k127_1429958_3 prephenate dehydrogenase K04517 - 1.3.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002671 420.0
PYH3_k127_1429958_4 Oxygen tolerance - - - 0.0000000000000000000000000000005019 126.0
PYH3_k127_1429958_5 - - - - 0.000000000000000000000000002003 115.0
PYH3_k127_1451093_0 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001591 489.0
PYH3_k127_1451093_1 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001437 364.0
PYH3_k127_1451093_3 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000001014 172.0
PYH3_k127_1451093_4 TIGRFAM DJ-1 family protein K03152 - 3.5.1.124 0.0000000000000000000000000000005628 128.0
PYH3_k127_147333_0 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 7.673e-242 756.0
PYH3_k127_147333_1 RNA-binding protein homologous to eukaryotic snRNP - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 554.0
PYH3_k127_147333_2 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 - 1.1.1.267 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 503.0
PYH3_k127_147333_3 Belongs to the CDS family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002969 413.0
PYH3_k127_147333_4 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 - 2.3.1.234 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008335 409.0
PYH3_k127_147333_5 Serine hydrolase K07002 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005995 314.0
PYH3_k127_147333_6 - - - - 0.0000000000000000000000000000000002042 134.0
PYH3_k127_1533789_0 2-acylglycerophosphoethanolamine acyltransferase K05939 - 2.3.1.40,6.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 528.0
PYH3_k127_1533789_1 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001001 507.0
PYH3_k127_1533789_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 430.0
PYH3_k127_1533789_3 Family of unknown function (DUF695) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001152 321.0
PYH3_k127_1533789_4 NlpC/P60 family K13694,K13695 - 3.4.17.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001621 282.0
PYH3_k127_1533789_5 HAD-superfamily hydrolase, subfamily IA, variant 1 K01091 - 3.1.3.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000002269 264.0
PYH3_k127_1533789_6 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001858 258.0
PYH3_k127_1533789_7 COGs COG0665 Glycine D-amino acid oxidase (deaminating) K15461 - 2.1.1.61 0.000000000000000000000000000000000005815 137.0
PYH3_k127_1567465_0 Diguanylate cyclase - - - 3.576e-267 840.0
PYH3_k127_1567465_1 ABC transporter permease K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002105 581.0
PYH3_k127_1567465_2 Outer membrane efflux protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007688 410.0
PYH3_k127_1567465_3 ABC transporter K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008663 352.0
PYH3_k127_1567465_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000001741 243.0
PYH3_k127_1567465_5 HPP family - - - 0.00000000000000000000000000000000000000000000000000000000000000009527 224.0
PYH3_k127_1567465_6 protein involved in response to NO K07234 - - 0.0000000000000000000000000000000000000000000004115 170.0
PYH3_k127_1567465_7 Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress K05916 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0008941,GO:0016491,GO:0016705,GO:0016708,GO:0044424,GO:0044464,GO:0051213,GO:0055114 1.14.12.17 0.0000000000000000000000000000005068 126.0
PYH3_k127_1608963_0 Belongs to the CarB family K01955 - 6.3.5.5 4.655e-254 785.0
PYH3_k127_1608963_1 rod shape-determining protein mreB K03569 - - 2.043e-209 652.0
PYH3_k127_1608963_2 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002622 242.0
PYH3_k127_1608963_3 Rod shape-determining protein MreC K03570 - - 0.0000000000000000000000000000000000000000002601 168.0
PYH3_k127_161066_0 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 0.0 1128.0
PYH3_k127_161066_1 penicillin-binding protein K05515 - 3.4.16.4 5.215e-311 961.0
PYH3_k127_161066_10 nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004023 370.0
PYH3_k127_161066_11 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001386 366.0
PYH3_k127_161066_12 Imidazoleglycerol-phosphate dehydratase K01089,K01693 - 3.1.3.15,4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003287 329.0
PYH3_k127_161066_13 Necessary for normal cell division and for the maintenance of normal septation K03978 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 316.0
PYH3_k127_161066_14 acetyltransferase K00619 - 2.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007283 271.0
PYH3_k127_161066_15 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000003355 261.0
PYH3_k127_161066_16 Ankyrin repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002039 255.0
PYH3_k127_161066_17 hmm pf01863 K07043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007622 256.0
PYH3_k127_161066_18 3-deoxy-d-manno-octulosonate 8-phosphate phosphatase K03270 - 3.1.3.45 0.00000000000000000000000000000000000000000000000000000000000000000006185 234.0
PYH3_k127_161066_19 Lipopolysaccharide transport periplasmic protein lpta K09774 - - 0.00000000000000000000000000000000000000000000000000000000000000008731 225.0
PYH3_k127_161066_2 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 5.562e-287 885.0
PYH3_k127_161066_20 Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA K07042 - - 0.0000000000000000000000000000000000000000000000000000000001115 207.0
PYH3_k127_161066_21 - - - - 0.000000000000000000000000000000000000000000000000008941 184.0
PYH3_k127_161066_22 - - - - 0.000000000000000000000000000000007901 132.0
PYH3_k127_161066_23 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 0.00000002786 55.0
PYH3_k127_161066_3 May be involved in recombinational repair of damaged DNA K03631 - - 9.239e-221 694.0
PYH3_k127_161066_4 lytic murein transglycosylase K08307 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002681 560.0
PYH3_k127_161066_5 UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006313 550.0
PYH3_k127_161066_6 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006861 506.0
PYH3_k127_161066_7 hydrolase, TatD K03424 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001667 432.0
PYH3_k127_161066_8 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 392.0
PYH3_k127_161066_9 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001852 374.0
PYH3_k127_1670091_0 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 6.083e-230 716.0
PYH3_k127_1670091_1 COG0457 FOG TPR repeat - - - 6.704e-199 631.0
PYH3_k127_1670091_10 - - - - 0.00000000000000000000000000000000000000000000000366 174.0
PYH3_k127_1670091_11 - - - - 0.0000000000000000000000000000000000000000000000189 172.0
PYH3_k127_1670091_12 transport system auxiliary component K18480 - - 0.000000000000000000000000000000000000000000009446 171.0
PYH3_k127_1670091_13 Protein conserved in bacteria - - - 0.000000000000000000000000000000000000000003532 157.0
PYH3_k127_1670091_2 Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis K00850 - 2.7.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000132 557.0
PYH3_k127_1670091_3 Methylenetetrahydrofolate reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009907 504.0
PYH3_k127_1670091_4 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005524 473.0
PYH3_k127_1670091_5 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001687 400.0
PYH3_k127_1670091_6 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 395.0
PYH3_k127_1670091_7 phosphoserine phosphatase K01079 - 3.1.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 382.0
PYH3_k127_1670091_8 G T U mismatch-specific DNA glycosylase - - - 0.0000000000000000000000000000000000000000000000000000000000000001348 223.0
PYH3_k127_1670091_9 nucleoside-diphosphate sugar epimerase K07071 - - 0.00000000000000000000000000000000000000000000000003188 190.0
PYH3_k127_171457_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 5.137e-296 910.0
PYH3_k127_171457_1 - - - - 0.0000000000000000000002098 97.0
PYH3_k127_1748290_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 5.276e-310 953.0
PYH3_k127_1748290_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001468 505.0
PYH3_k127_1748290_2 flagellar - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009449 397.0
PYH3_k127_1748290_3 membrane transporter protein K07090 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003008 343.0
PYH3_k127_1748290_4 beta-lactamase activity K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000326 237.0
PYH3_k127_1748290_5 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000003762 186.0
PYH3_k127_1748290_7 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 K10799 GO:0000209,GO:0000228,GO:0000242,GO:0000723,GO:0000781,GO:0000784,GO:0003674,GO:0003824,GO:0003950,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005635,GO:0005694,GO:0005737,GO:0005813,GO:0005815,GO:0005829,GO:0005856,GO:0006139,GO:0006259,GO:0006464,GO:0006471,GO:0006725,GO:0006807,GO:0006996,GO:0008104,GO:0008150,GO:0008152,GO:0009889,GO:0009891,GO:0009892,GO:0009893,GO:0009894,GO:0009896,GO:0009966,GO:0009967,GO:0009987,GO:0010556,GO:0010557,GO:0010604,GO:0010605,GO:0010638,GO:0010639,GO:0010646,GO:0010647,GO:0012505,GO:0015630,GO:0016043,GO:0016567,GO:0016740,GO:0016757,GO:0016763,GO:0019219,GO:0019222,GO:0019538,GO:0019899,GO:0023051,GO:0023056,GO:0030111,GO:0030162,GO:0030177,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031328,GO:0031329,GO:0031331,GO:0031967,GO:0031974,GO:0031975,GO:0031981,GO:0032200,GO:0032204,GO:0032205,GO:0032206,GO:0032210,GO:0032212,GO:0032268,GO:0032270,GO:0032446,GO:0032501,GO:0032502,GO:0033036,GO:0033043,GO:0033044,GO:0033365,GO:0034502,GO:0034613,GO:0034641,GO:0035264,GO:0036211,GO:0040007,GO:0040008,GO:0040014,GO:0042176,GO:0042592,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043254,GO:0043412,GO:0044087,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0044422,GO:0044424,GO:0044427,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044450,GO:0044454,GO:0044464,GO:0045732,GO:0045862,GO:0045934,GO:0045935,GO:0046483,GO:0048471,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048583,GO:0048584,GO:0048589,GO:0048638,GO:0050789,GO:0050793,GO:0050794,GO:0051052,GO:0051053,GO:0051054,GO:0051128,GO:0051129,GO:0051130,GO:0051171,GO:0051172,GO:0051173,GO:0051179,GO:0051239,GO:0051246,GO:0051247,GO:0051276,GO:0051641,GO:0060249,GO:0060255,GO:0060828,GO:0065007,GO:0065008,GO:0070013,GO:0070198,GO:0070212,GO:0070213,GO:0070647,GO:0070727,GO:0071704,GO:0071840,GO:0080090,GO:0090263,GO:0090304,GO:0090364,GO:0097110,GO:0098687,GO:1901360,GO:1901564,GO:1903050,GO:1903052,GO:1903362,GO:1903364,GO:1904353,GO:1904355,GO:1904356,GO:1904357,GO:1904358,GO:2000058,GO:2000060,GO:2000112,GO:2000278,GO:2000573,GO:2001251,GO:2001252 2.4.2.30 0.00000000003437 74.0
PYH3_k127_181499_0 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 456.0
PYH3_k127_181499_1 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008268 439.0
PYH3_k127_181499_10 chemotaxis K03408 - - 0.00000000000002414 75.0
PYH3_k127_181499_2 Signal transducing histidine kinase, homodimeric domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001287 403.0
PYH3_k127_181499_3 HEAT repeats - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004773 248.0
PYH3_k127_181499_4 Two component signalling adaptor domain K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004088 247.0
PYH3_k127_181499_5 PFAM response regulator receiver K03407,K03413 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000005445 206.0
PYH3_k127_181499_6 GGDEF domain K03413 - - 0.000000000000000000000000000000000000000000000000003599 183.0
PYH3_k127_181499_8 chemotaxis K03408 - - 0.00000000000000000000000000007331 121.0
PYH3_k127_182826_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 2.152e-260 805.0
PYH3_k127_182826_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 540.0
PYH3_k127_182826_2 PFAM Ferredoxin thioredoxin reductase catalytic beta chain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006183 443.0
PYH3_k127_182826_3 ErfK YbiS YcfS YnhG family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000002037 242.0
PYH3_k127_182826_4 Binds to the 23S rRNA K02939 - - 0.00000000000000000000000000000000000000003713 157.0
PYH3_k127_182826_5 - - - - 0.00000000000000000003041 93.0
PYH3_k127_182826_6 flagellar protein FliS K02422 - - 0.000006792 48.0
PYH3_k127_1849189_0 Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA K06917 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001502 537.0
PYH3_k127_1849189_1 Synthesizes selenophosphate from selenide and ATP K01008 - 2.7.9.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001354 270.0
PYH3_k127_1849189_2 MgtC family - - - 0.000000000000000005991 84.0
PYH3_k127_194229_0 Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate K01007 - 2.7.9.2 5.343e-311 968.0
PYH3_k127_194229_1 Putative diguanylate phosphodiesterase - - - 2.585e-260 821.0
PYH3_k127_194229_2 Belongs to the peptidase M16 family - - - 1.046e-227 715.0
PYH3_k127_194229_3 Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor K00254 - 1.3.5.2 2.021e-205 642.0
PYH3_k127_194229_4 zinc metalloprotease K11749 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 552.0
PYH3_k127_194229_5 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003936 544.0
PYH3_k127_194229_6 dehydrogenase K00076 - 1.1.1.159 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 500.0
PYH3_k127_194229_7 ABC transporter K11085 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000603 376.0
PYH3_k127_194229_8 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006607 351.0
PYH3_k127_194229_9 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000003042 296.0
PYH3_k127_200339_0 Belongs to the AAA ATPase family - - - 6.878e-218 681.0
PYH3_k127_200339_1 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 529.0
PYH3_k127_200339_2 Molybdenum cofactor biosynthesis protein K03831 - 2.7.7.75 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006516 326.0
PYH3_k127_200339_3 Chemotaxis protein CheW K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001324 267.0
PYH3_k127_200339_4 cheY-homologous receiver domain K03413 - - 0.0000000000000000000000000000000000000000000000000000000000001368 214.0
PYH3_k127_200339_5 outer membrane porin, OprD family - - - 0.0000000000000000000000000000000004914 147.0
PYH3_k127_200339_6 PFAM Methyl-accepting chemotaxis protein (MCP) signaling domain K03406,K05875 - - 0.000000000000000000001334 97.0
PYH3_k127_2009193_0 Belongs to the peptidase S41A family K03797 - 3.4.21.102 5.121e-235 732.0
PYH3_k127_2009193_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 - 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001488 528.0
PYH3_k127_2009193_10 S4 domain K14761 - - 0.0000000000000000000000006944 106.0
PYH3_k127_2009193_11 Important for reducing fluoride concentration in the cell, thus reducing its toxicity K06199 GO:0003674,GO:0005215,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0006811,GO:0006820,GO:0008150,GO:0008509,GO:0015075,GO:0015103,GO:0015318,GO:0015698,GO:0016020,GO:0016021,GO:0022857,GO:0031224,GO:0031226,GO:0034220,GO:0044425,GO:0044459,GO:0044464,GO:0051179,GO:0051234,GO:0055085,GO:0071944,GO:0098656,GO:0098660,GO:0098661,GO:1903424,GO:1903425 - 0.00000000000001411 78.0
PYH3_k127_2009193_2 abc transporter atp-binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007257 507.0
PYH3_k127_2009193_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001985 499.0
PYH3_k127_2009193_4 Belongs to the SAICAR synthetase family K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004729 453.0
PYH3_k127_2009193_5 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003517 412.0
PYH3_k127_2009193_6 Belongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002857 305.0
PYH3_k127_2009193_7 ABC transporter, ATP-binding protein K02032 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 288.0
PYH3_k127_2009193_8 RNA-binding protein - - - 0.000000000000000000000000000000000000000000000001298 174.0
PYH3_k127_2009193_9 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000002529 147.0
PYH3_k127_2025797_0 An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay K12574 - - 0.0 1247.0
PYH3_k127_2025797_1 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K03406 - - 1.148e-266 833.0
PYH3_k127_2025797_10 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.000000000000001456 76.0
PYH3_k127_2025797_11 CheW-like domain K03408 - - 0.000000002917 66.0
PYH3_k127_2025797_2 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 1.931e-211 659.0
PYH3_k127_2025797_3 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002607 474.0
PYH3_k127_2025797_4 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001172 458.0
PYH3_k127_2025797_5 Nucleoside-specific channel-forming protein, Tsx - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005811 353.0
PYH3_k127_2025797_6 peptidase M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002769 347.0
PYH3_k127_2025797_7 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008666 340.0
PYH3_k127_2025797_8 phosphorylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 322.0
PYH3_k127_2025797_9 PAS fold K03776 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002431 239.0
PYH3_k127_2049937_0 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 3.653e-289 889.0
PYH3_k127_2049937_1 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 2.902e-231 718.0
PYH3_k127_2049937_2 sulfate adenylyltransferase K00958 - 2.7.7.4 9.874e-219 683.0
PYH3_k127_2049937_3 Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl- D-erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2- phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4- cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF) K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003779 576.0
PYH3_k127_2049937_4 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002091 390.0
PYH3_k127_2049937_5 Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG) K01095 - 3.1.3.27 0.0000000000000000000000000000000000000265 145.0
PYH3_k127_2049937_6 response regulator - - - 0.00001194 56.0
PYH3_k127_2095005_0 Belongs to the heme-copper respiratory oxidase family K00404 - 1.9.3.1 1.443e-288 889.0
PYH3_k127_2095005_1 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 2.023e-256 792.0
PYH3_k127_2095005_10 FixH - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001053 257.0
PYH3_k127_2095005_11 PDP protein - - - 0.000000000000000000000000000000000000000000000000000000000000000005118 229.0
PYH3_k127_2095005_12 COG3893 inactivated superfamily I helicase - - - 0.0000000000000000000000000000000000000000000002102 170.0
PYH3_k127_2095005_13 Flagellar FliJ protein - - - 0.000000000000000000000000000001237 126.0
PYH3_k127_2095005_14 cytochrome c oxidase K00407 - - 0.00000000000000000000000005675 108.0
PYH3_k127_2095005_15 Family of unknown function (DUF4006) - - - 0.0000000000000001181 85.0
PYH3_k127_2095005_2 Belongs to the CarA family K01956 - 6.3.5.5 1.793e-216 675.0
PYH3_k127_2095005_3 Aminotransferase - - - 2.873e-202 634.0
PYH3_k127_2095005_4 PFAM tRNA synthetase class II (G H P and S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001532 450.0
PYH3_k127_2095005_5 C-type cytochrome. Part of the cbb3-type cytochrome c oxidase complex K00406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 439.0
PYH3_k127_2095005_6 cytochrome c oxidase, cbb3-type, subunit II K00405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005821 414.0
PYH3_k127_2095005_7 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin K06153 - 3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002498 342.0
PYH3_k127_2095005_8 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007522 313.0
PYH3_k127_2095005_9 protein conserved in bacteria K09804 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001296 297.0
PYH3_k127_20975_0 Histidine kinase-like ATPases K03407 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002709 501.0
PYH3_k127_20975_1 Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000917 479.0
PYH3_k127_20975_2 cheY-homologous receiver domain K03413 - - 0.00000000000000000000000000000000000000000001239 167.0
PYH3_k127_224625_0 PFAM biotin lipoyl attachment domain-containing protein K01960 - 6.4.1.1 0.0 1107.0
PYH3_k127_224625_1 Response regulator receiver K03415 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003145 527.0
PYH3_k127_224625_2 molybdopterin oxidoreductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005928 432.0
PYH3_k127_224625_3 Protein of unknown function (DUF1722) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001315 392.0
PYH3_k127_224625_4 Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions K01507 - 3.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004305 352.0
PYH3_k127_224625_5 lytic transglycosylase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000004816 251.0
PYH3_k127_224625_6 Belongs to the glutathione peroxidase family K00432 - 1.11.1.9 0.00000000000000000000000000000000000000000000000000000000000000000003962 237.0
PYH3_k127_224625_7 - - - - 0.000000000000000000000000000000000000000002836 156.0
PYH3_k127_224625_8 - - - - 0.000000000000000000000000000000000000000261 155.0
PYH3_k127_227074_0 diguanylate cyclase - - - 9.395e-207 661.0
PYH3_k127_227074_2 HD domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000754 347.0
PYH3_k127_227074_3 chain release factor K15034 - - 0.0000000000000000000000000000000000000000000000000000000000000003128 222.0
PYH3_k127_227074_4 2'-5' RNA ligase K01975 - 3.1.4.58 0.0000000000000000000000000000000000000000000000000000007237 197.0
PYH3_k127_227074_5 cheY-homologous receiver domain - - - 0.0000000000000000000000000000000000000000000000000000009583 196.0
PYH3_k127_227074_6 Protein of unknown function (DUF503) K09764 - - 0.00000000000000000000000006173 111.0
PYH3_k127_227074_7 diguanylate cyclase - - - 0.000000000002097 76.0
PYH3_k127_227074_8 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.000000001596 60.0
PYH3_k127_2462793_0 Cytochrome c biogenesis protein - - - 0.0 1618.0
PYH3_k127_2462793_1 Putative glycosyl hydrolase domain - - - 3.203e-218 683.0
PYH3_k127_2462793_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 2.751e-214 668.0
PYH3_k127_2462793_3 COG0513 Superfamily II DNA and RNA K11927 - 3.6.4.13 7.565e-205 645.0
PYH3_k127_2462793_4 ATP-binding protein K02017 - 3.6.3.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 432.0
PYH3_k127_2462793_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004631 380.0
PYH3_k127_2462793_6 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003365 349.0
PYH3_k127_2462793_7 SMART GGDEF domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002257 297.0
PYH3_k127_2462793_8 ABC transporter permease K02018 - - 0.000000000000000000000000001879 111.0
PYH3_k127_2462793_9 Methyltransferase, chemotaxis proteins K00575 - 2.1.1.80 0.000000000003659 68.0
PYH3_k127_249319_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K17050 - - 0.0 1857.0
PYH3_k127_249319_1 4Fe-4S dicluster domain K17051 - - 4.298e-241 745.0
PYH3_k127_249319_2 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 3.953e-197 621.0
PYH3_k127_249319_3 Cytochrome c-552 DMSO reductase-like, heme-binding domain K17052 - - 2.865e-196 617.0
PYH3_k127_249319_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008831 557.0
PYH3_k127_249319_5 4Fe-4S dicluster domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005138 428.0
PYH3_k127_249319_6 lyase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005976 329.0
PYH3_k127_249319_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001725 233.0
PYH3_k127_249319_8 Nitrate reductase delta subunit - - - 0.0000000000000000000000000000000000000000000000000000000000009571 215.0
PYH3_k127_249797_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 0.0 1499.0
PYH3_k127_249797_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00261,K00262 GO:0003674,GO:0003824,GO:0004353,GO:0004354,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006536,GO:0006537,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016491,GO:0016638,GO:0016639,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0055114,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 1.4.1.3,1.4.1.4 1.397e-240 749.0
PYH3_k127_249797_2 Domain present in phytochromes and cGMP-specific phosphodiesterases. - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001165 515.0
PYH3_k127_249797_3 Signal transduction protein - - - 0.000000000000000000000000000000000000000000000000000000000000007793 218.0
PYH3_k127_249797_4 methyl-accepting chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000007961 214.0
PYH3_k127_2526348_0 Participates in both transcription termination and antitermination K02600 - - 4.367e-203 637.0
PYH3_k127_2526348_1 ABC transporter permease K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001425 534.0
PYH3_k127_2526348_2 Receptor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 529.0
PYH3_k127_2526348_3 Enoyl- acyl-carrier-protein reductase NADH K00208 GO:0003674,GO:0003824,GO:0004312,GO:0004318,GO:0006082,GO:0006629,GO:0006631,GO:0006633,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009987,GO:0016043,GO:0016053,GO:0016491,GO:0016627,GO:0016628,GO:0016740,GO:0016746,GO:0016747,GO:0019752,GO:0022607,GO:0030497,GO:0032787,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046394,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0055114,GO:0065003,GO:0071704,GO:0071840,GO:0072330,GO:1901576 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001631 471.0
PYH3_k127_2526348_4 - - - - 0.0000000000000000000000000000000000001715 145.0
PYH3_k127_2550476_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1186.0
PYH3_k127_2550476_1 penicillin-binding protein K05366 - 2.4.1.129,3.4.16.4 0.0 1148.0
PYH3_k127_2550476_2 8-amino-7-oxononanoate synthase K00652 - 2.3.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 526.0
PYH3_k127_2550476_3 nucleotide-binding protein implicated in inhibition of septum formation K06287 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 317.0
PYH3_k127_2550476_4 membrane-associated protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001847 315.0
PYH3_k127_2550476_5 Abc transporter K02031 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000236 317.0
PYH3_k127_2550476_7 integral membrane protein - - - 0.0000003203 51.0
PYH3_k127_2607591_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.5e-323 992.0
PYH3_k127_2607591_1 Belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family K03455 - - 2.932e-196 622.0
PYH3_k127_2644298_0 NUBPL iron-transfer P-loop NTPase K03496 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004337 363.0
PYH3_k127_2644298_1 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000003766 273.0
PYH3_k127_2644298_2 chemotaxis K03408 - - 0.0001792 48.0
PYH3_k127_2644760_0 Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA K04066 - - 2.016e-278 863.0
PYH3_k127_2644760_1 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 - 1.17.7.1,1.17.7.3 4.111e-210 655.0
PYH3_k127_2644760_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 0.0000007588 51.0
PYH3_k127_2697146_0 Belongs to the UbiD family K03182 - 4.1.1.98 0.0 1047.0
PYH3_k127_2697146_1 argininosuccinate lyase K01755 - 4.3.2.1 4.965e-266 823.0
PYH3_k127_2697146_2 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004391 520.0
PYH3_k127_2697146_3 Thioredoxin - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 419.0
PYH3_k127_2697146_4 - - - - 0.00000000000000000000000000000000000000000000009327 172.0
PYH3_k127_2697146_5 redox protein regulator of disulfide bond formation K07397 - - 0.000000000000000004064 83.0
PYH3_k127_2701923_0 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1394.0
PYH3_k127_2701923_1 COGs COG0493 NADPH-dependent glutamate synthase beta chain and related oxidoreductase K15022 - 1.17.1.10 0.0 1303.0
PYH3_k127_2701923_2 COG1034 NADH dehydrogenase NADH ubiquinone oxidoreductase 75 kD subunit (chain G) K00336 - 1.6.5.3 0.0 1200.0
PYH3_k127_2701923_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 5.484e-196 614.0
PYH3_k127_2701923_4 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001171 597.0
PYH3_k127_2701923_5 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002419 400.0
PYH3_k127_2701923_6 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002291 283.0
PYH3_k127_2701923_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.000000000000000000000000000000000000000000000007322 173.0
PYH3_k127_2701923_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333 - 1.6.5.3 0.00000000000000000000000000000000000005826 141.0
PYH3_k127_2701923_9 putative NADH-ubiquinone oxidoreductase chain E K00334 - 1.6.5.3 0.0000000000000000000000000000004607 123.0
PYH3_k127_27166_0 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 4.959e-238 739.0
PYH3_k127_27166_1 Belongs to the ALAD family K01698 - 4.2.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 605.0
PYH3_k127_27166_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 519.0
PYH3_k127_27166_3 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001512 345.0
PYH3_k127_27166_4 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 333.0
PYH3_k127_27166_5 Specifically methylates the N7 position of guanine in position 527 of 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002942 271.0
PYH3_k127_27166_7 - - - - 0.0000000000000000000000000000006281 122.0
PYH3_k127_27166_8 Prokaryotic metallothionein K06950 - - 0.000000000000000000001002 96.0
PYH3_k127_2775576_0 Saccharopine dehydrogenase K00290 - 1.5.1.7 2.256e-248 768.0
PYH3_k127_2775576_1 signal transduction protein containing EAL and modified HD-GYP domains - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005058 563.0
PYH3_k127_2775576_2 Recycling of diacylglycerol produced during the turnover of membrane phospholipid K00901 - 2.7.1.107 0.000000000000000000000000000000000000000000000000000000112 196.0
PYH3_k127_2775576_3 Belongs to the MEMO1 family K06990 - - 0.00000000000000000000000000000000000000000000001071 175.0
PYH3_k127_2788092_0 S-adenosyl-L-methionine-dependent methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009589 391.0
PYH3_k127_2788092_1 FMN binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000004296 232.0
PYH3_k127_2788092_2 - - - - 0.00000000000000000000000000000000000000000000000000006914 190.0
PYH3_k127_2788092_5 - - - - 0.0000000000000000000000000006158 113.0
PYH3_k127_2806855_0 arginine decarboxylase K01585 - 4.1.1.19 0.0 1166.0
PYH3_k127_2806855_1 COGs COG0069 Glutamate synthase domain 2 - - - 1.805e-237 747.0
PYH3_k127_2806855_2 serine acetyltransferase K00640 - 2.3.1.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 424.0
PYH3_k127_2806855_3 histidyl-tRNA synthetase K01892 - 6.1.1.21 0.00000000004777 63.0
PYH3_k127_2806855_4 LPP20 lipoprotein - - - 0.000002034 58.0
PYH3_k127_2806880_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1740.0
PYH3_k127_2806880_1 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 5.499e-288 887.0
PYH3_k127_2806880_10 HD domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003338 360.0
PYH3_k127_2806880_11 Polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007591 303.0
PYH3_k127_2806880_12 PFAM Archease protein family (DUF101 UPF0211) K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000001674 168.0
PYH3_k127_2806880_13 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.00000000000000000000001711 100.0
PYH3_k127_2806880_14 - - - - 0.000000000000001822 78.0
PYH3_k127_2806880_16 - - - - 0.00000105 51.0
PYH3_k127_2806880_18 - - - - 0.00004487 45.0
PYH3_k127_2806880_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 2.148e-265 820.0
PYH3_k127_2806880_3 o-acetylhomoserine K01740 - 2.5.1.49 6.923e-240 745.0
PYH3_k127_2806880_4 Belongs to the RtcB family K14415 - 6.5.1.3 7.689e-221 695.0
PYH3_k127_2806880_5 COG0436 Aspartate tyrosine aromatic aminotransferase - - - 2.776e-220 686.0
PYH3_k127_2806880_6 Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine K00641 - 2.3.1.31 4.621e-220 686.0
PYH3_k127_2806880_7 Belongs to the CinA family K03743 - 3.5.1.42 3.855e-194 611.0
PYH3_k127_2806880_8 hydrolase K01501 - 3.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 464.0
PYH3_k127_2806880_9 involved in molybdopterin and thiamine biosynthesis family 2 K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001528 386.0
PYH3_k127_2817444_0 DnaJ domain protein K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 426.0
PYH3_k127_2817444_1 Hydrolase K12251 - 3.5.1.53 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004606 403.0
PYH3_k127_2817444_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K02346 - 2.7.7.7 0.0000000000000000000000000001956 116.0
PYH3_k127_283077_0 Belongs to the 5'-nucleotidase family K01119,K17224 - 3.1.3.6,3.1.4.16 0.0 1104.0
PYH3_k127_283077_1 peptidase M23 - - - 3.177e-246 766.0
PYH3_k127_283077_10 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000072 251.0
PYH3_k127_283077_11 Sulfur oxidation protein SoxY K17226 - - 0.000000000000000000000000000000000000000000000000000000000000000000000002764 246.0
PYH3_k127_283077_12 DsrE/DsrF-like family K09004 - - 0.000000000000000000000000000000000000000000000000000000000000002327 220.0
PYH3_k127_283077_13 DsrE/DsrF-like family K09004 - - 0.00000000000000000000000000000000000000000000000000000009612 198.0
PYH3_k127_283077_14 oxidation protein SoxZ K17227 - - 0.000000000000000000000000000000000000000000000000000108 187.0
PYH3_k127_283077_15 COG1214 Inactive homolog of metal-dependent proteases - - - 0.000000000000000000000000000000000000000000007607 167.0
PYH3_k127_283077_16 Nucleic-acid-binding protein implicated in transcription termination K02600,K07742 - - 0.0000000000000000000000000001161 116.0
PYH3_k127_283077_2 Receptor - - - 2.235e-211 667.0
PYH3_k127_283077_3 Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate K00872 - 2.7.1.39 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002702 551.0
PYH3_k127_283077_4 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003698 510.0
PYH3_k127_283077_5 Domain of unknown function DUF302 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002952 442.0
PYH3_k127_283077_6 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003339 392.0
PYH3_k127_283077_7 Thiosulfate-oxidizing multienzyme system protein SoxA K17222 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004634 389.0
PYH3_k127_283077_8 DHH family K06881 - 3.1.13.3,3.1.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 374.0
PYH3_k127_283077_9 Cytochrome c K17223 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002267 285.0
PYH3_k127_2870522_0 COG0642 Signal transduction histidine kinase - - - 2.411e-312 967.0
PYH3_k127_2870522_1 Histidine kinase K20972 - - 2.979e-290 902.0
PYH3_k127_2870522_10 Catalyzes the conversion of S-adenosyl-L-methionine (SAM) to carboxy-S-adenosyl-L-methionine (Cx-SAM) K15256 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002328 371.0
PYH3_k127_2870522_11 flagellar motor K02557 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000015 360.0
PYH3_k127_2870522_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003473 347.0
PYH3_k127_2870522_13 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004654 310.0
PYH3_k127_2870522_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003033 307.0
PYH3_k127_2870522_15 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001743 318.0
PYH3_k127_2870522_16 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 - 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000000000000002821 255.0
PYH3_k127_2870522_17 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07305,K12267 - 1.8.4.11,1.8.4.12 0.00000000000000000000000000000000000000000000000000000000000000000000373 235.0
PYH3_k127_2870522_18 Highly conserved protein containing a thioredoxin domain - - - 0.00000000000000000000000000000000000000000000000001623 183.0
PYH3_k127_2870522_19 Belongs to the bacterial histone-like protein family K03530 - - 0.000000000000000000000000000000000000000000009798 163.0
PYH3_k127_2870522_2 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 4.848e-239 747.0
PYH3_k127_2870522_20 DNA-binding protein - - - 0.000000000000000000000000000000000001352 139.0
PYH3_k127_2870522_21 - - - - 0.0000000000000000000005141 97.0
PYH3_k127_2870522_22 Cupin domain K11312 - - 0.000000000000000007943 86.0
PYH3_k127_2870522_23 Na H antiporter - - - 0.0003061 43.0
PYH3_k127_2870522_3 chemotaxis protein K03406 - - 1.629e-228 718.0
PYH3_k127_2870522_4 fructose-bisphosphate aldolase K01624 - 4.1.2.13 2.931e-207 647.0
PYH3_k127_2870522_5 Peptidase family M23 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009407 565.0
PYH3_k127_2870522_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001397 545.0
PYH3_k127_2870522_7 peptidylprolyl isomerase K01802 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001558 438.0
PYH3_k127_2870522_8 forms the ion channels that couple flagellar rotation to proton sodium motive force across the membrane and forms the stator elements of the rotary flagellar machine K02556 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 429.0
PYH3_k127_2870522_9 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008067 369.0
PYH3_k127_2896893_0 Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source K02224 - 6.3.5.11,6.3.5.9 1.502e-219 686.0
PYH3_k127_2896893_1 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.0000000000000000000000000000000000000000000000000000000000000005804 223.0
PYH3_k127_2896893_2 homoserine kinase type II (Protein kinase fold) K02204 - 2.7.1.39 0.000000000000000000000000000000000000000000000000000000000007763 216.0
PYH3_k127_2896893_3 TIGRFAM cob(II)yrinic acid a,c-diamide reductase K04719 - 1.13.11.79 0.0000000000000000000000000000000000000000001657 161.0
PYH3_k127_2905810_0 Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) K00937 - 2.7.4.1 0.0 1268.0
PYH3_k127_2905810_1 NYN domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008729 452.0
PYH3_k127_2905810_2 dinuclear metal center protein, YbgI K22391 - 3.5.4.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003675 435.0
PYH3_k127_2905810_3 COG1579 Zn-ribbon protein possibly nucleic acid-binding K07164,K22391 - 3.5.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007566 388.0
PYH3_k127_2905810_4 Tetratricopeptide repeat - - - 0.0000000000000000000000000000000000000000000000000000001303 200.0
PYH3_k127_2905810_5 3-deoxy-d-manno-octulosonic-acid transferase K02527 - 2.4.99.12,2.4.99.13,2.4.99.14,2.4.99.15 0.0000000000000000000000000000000000033 139.0
PYH3_k127_2929682_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.743e-258 799.0
PYH3_k127_2929682_1 Metallophosphoesterase K07098 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006434 601.0
PYH3_k127_2929682_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002743 421.0
PYH3_k127_2929682_3 D-alanyl-D-alanine carboxypeptidase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001954 362.0
PYH3_k127_2929682_4 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002341 301.0
PYH3_k127_2929682_5 Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor K03752 - 2.7.7.77 0.00000000000000000000000000000000000000000000000000000000000000000000000006985 253.0
PYH3_k127_2929682_6 COG1393 Arsenate reductase and related K00537 - 1.20.4.1 0.0000000000000000000000000000000000000000000009306 168.0
PYH3_k127_2929682_7 4Fe-4S dicluster domain - - - 0.0000000000000000000000000002804 113.0
PYH3_k127_2929682_8 Belongs to the UPF0250 family - - - 0.000000000000000000000001158 106.0
PYH3_k127_3033694_0 Belongs to the DNA photolyase family K01669 - 4.1.99.3 4.548e-211 665.0
PYH3_k127_3033694_1 Protein of unknown function (DUF1722) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002559 387.0
PYH3_k127_3033694_2 DnaJ domain protein K05801 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000164 357.0
PYH3_k127_3033694_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001178 274.0
PYH3_k127_3033694_4 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000008135 256.0
PYH3_k127_3033694_5 Transcriptional regulatory protein, C terminal - - - 0.0000000000000000000004587 111.0
PYH3_k127_3074121_0 COG0739 Membrane proteins related to metalloendopeptidases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 594.0
PYH3_k127_3074121_1 Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA K03439 - 2.1.1.33 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001703 554.0
PYH3_k127_3074121_2 Cell division protein FtsX K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003191 403.0
PYH3_k127_3074121_3 ABC transporter K09812 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001551 259.0
PYH3_k127_3074121_4 Fibronectin type 3 domain-containing protein K06882 - - 0.0000000000000000000000000000000000000000000000000000000000000005303 223.0
PYH3_k127_3074121_5 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02393 - - 0.000000000000000000000002271 102.0
PYH3_k127_3091122_0 Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001989 606.0
PYH3_k127_3091122_1 Protein of unknown function (DUF475) K09799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001668 512.0
PYH3_k127_3091122_2 PFAM Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004206 366.0
PYH3_k127_3091122_3 Prolyl 4-hydroxylase alpha subunit homologues. K07394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001023 326.0
PYH3_k127_3091122_4 phosphomannomutase K15778 - 5.4.2.2,5.4.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000002892 260.0
PYH3_k127_3091122_5 Biopolymer transporter ExbB K03561 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000358 243.0
PYH3_k127_3091122_6 biopolymer transport protein K03559 - - 0.000000000000000000000000000000000000000000000000000000000000006598 217.0
PYH3_k127_3091122_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000006556 176.0
PYH3_k127_3091122_8 DNA-binding protein - - - 0.0000000000000000000000000000000000001836 141.0
PYH3_k127_3128082_0 Glutamate-1-semialdehyde aminotransferase K01845 - 5.4.3.8 6.355e-249 772.0
PYH3_k127_3128082_1 Belongs to the HpcH HpaI aldolase family K01644 - 4.1.3.34 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005846 451.0
PYH3_k127_3128082_2 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001207 341.0
PYH3_k127_3128082_3 - - - - 0.00000000000000000000000000000000000000000000000001333 186.0
PYH3_k127_3128082_4 energy transducer activity K03832 - - 0.0000000000000000000000000000000000002485 149.0
PYH3_k127_3128082_5 Cytochrome c - - - 0.00000000000000000000000001189 113.0
PYH3_k127_3128082_6 COG0841 Cation multidrug efflux pump - - - 0.00000000000000000000000006582 108.0
PYH3_k127_3128082_7 Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter - - - 0.0000000000000000000000007858 108.0
PYH3_k127_3154772_0 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002476 485.0
PYH3_k127_3154772_1 uptake protein K03499 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006089 358.0
PYH3_k127_3154772_2 Polysaccharide deacetylase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 353.0
PYH3_k127_3154772_3 Potassium uptake protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007037 265.0
PYH3_k127_3154772_5 Rhodanese-like domain - - - 0.00000000000000000000000000000000000000000000000000003376 193.0
PYH3_k127_3154772_7 Translation initiation factor SUI1 K03113 - - 0.0000000000000000000000000000000000000000000006033 168.0
PYH3_k127_316142_0 Abc transporter K02035 - - 6.044e-271 839.0
PYH3_k127_316142_1 carbonic anhydrase K01674 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 391.0
PYH3_k127_316142_2 Sulfatase K03760 - 2.7.8.43 0.0000000000000000000000000000000000000000000000000000000000000000000000003106 248.0
PYH3_k127_316142_3 Hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000007966 130.0
PYH3_k127_3167298_0 Major facilitator superfamily K05820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006137 502.0
PYH3_k127_3167298_1 mechanosensitive ion channel K03442 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003139 354.0
PYH3_k127_3167298_2 RDD family - - - 0.0000000000000000000000000000000000000000000000000000000000000002578 224.0
PYH3_k127_3167298_3 Nitroreductase - - - 0.0000000000000000000000000000000000000000000000000000001443 196.0
PYH3_k127_3180558_0 silver ion transport K07787,K15726 - - 0.0 1274.0
PYH3_k127_3180558_1 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005404 414.0
PYH3_k127_3180558_2 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000004165 306.0
PYH3_k127_3180558_3 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000001275 269.0
PYH3_k127_3180558_4 Outer membrane efflux protein K15725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004365 256.0
PYH3_k127_3180558_5 Outer membrane efflux protein K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004785 252.0
PYH3_k127_3180558_6 Barrel-sandwich domain of CusB or HlyD membrane-fusion K15727 - - 0.000000000002406 78.0
PYH3_k127_3204070_0 Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA K00674 - 2.3.1.117 1.048e-220 688.0
PYH3_k127_3204070_1 COG0791 Cell wall-associated hydrolases (invasion-associated proteins) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003002 561.0
PYH3_k127_3204070_2 phage repressor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003217 415.0
PYH3_k127_3204070_3 Flagellar hook protein flgE - - - 0.0000000000000000000000000000001428 126.0
PYH3_k127_3204070_4 Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide K03216 - 2.1.1.207 0.0000000000001388 70.0
PYH3_k127_3301480_0 diguanylate cyclase - - - 0.0 1035.0
PYH3_k127_3301480_1 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000119 549.0
PYH3_k127_34990_0 Cytochrome c oxidase accessory protein - - - 8.523e-246 766.0
PYH3_k127_34990_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 590.0
PYH3_k127_34990_2 Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11785 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 498.0
PYH3_k127_34990_3 cell wall formation K00075 - 1.3.1.98 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003799 436.0
PYH3_k127_34990_4 PFAM Resolvase, N terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 286.0
PYH3_k127_34990_5 Flagellar biosynthetic protein FliQ K02420 - - 0.0000000000000000000000000000000000000000001609 159.0
PYH3_k127_3528142_0 Part of the ABC transporter complex PstSACB involved in phosphate import K02040 - - 3.286e-195 611.0
PYH3_k127_3528142_1 tRNA nucleotidyltransferase poly(A) polymerase K00974 - 2.7.7.72 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 579.0
PYH3_k127_3528142_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000518 552.0
PYH3_k127_3528142_3 Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system K02036 - 3.6.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001837 500.0
PYH3_k127_3528142_4 probably responsible for the translocation of the substrate across the membrane K02037 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002369 494.0
PYH3_k127_3528142_5 phosphate transport system permease K02038 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008432 494.0
PYH3_k127_3528142_6 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003323 332.0
PYH3_k127_3528142_7 PhoU family K02039 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005311 302.0
PYH3_k127_3528142_8 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001321 282.0
PYH3_k127_3528142_9 Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane - - - 0.00000000000001421 74.0
PYH3_k127_356066_0 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits (eIF-2Bgamma eIF-2Bepsilon) K16881 - 2.7.7.13,5.4.2.8 0.0 1326.0
PYH3_k127_356066_1 hydrogenase expression formation protein K04655 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 436.0
PYH3_k127_356066_2 Belongs to the HypD family K04654 - - 0.00000000000000000000000000000000000000000000000000000000000197 211.0
PYH3_k127_356066_3 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.000000000000000000000000000000000000000000001247 167.0
PYH3_k127_3704460_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 7.86e-234 727.0
PYH3_k127_3704460_1 ATPase (AAA K07133 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001154 557.0
PYH3_k127_3704460_10 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000002925 288.0
PYH3_k127_3704460_11 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002959 274.0
PYH3_k127_3704460_12 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001852 266.0
PYH3_k127_3704460_13 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000001046 243.0
PYH3_k127_3704460_14 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 - - 0.000000000000000000000000000000000000000000000000000000000000000000007948 234.0
PYH3_k127_3704460_15 Binds to the 23S rRNA K02876 - - 0.0000000000000000000000000000000000000000000000000000000000000003082 221.0
PYH3_k127_3704460_16 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.0000000000000000000000000000000000000000000000000000000002185 204.0
PYH3_k127_3704460_17 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000000000000009069 199.0
PYH3_k127_3704460_18 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 - - 0.000000000000000000000000000000000000000000000000000001263 191.0
PYH3_k127_3704460_19 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.000000000000000000000000000000000000000000000000000003432 191.0
PYH3_k127_3704460_2 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004188 532.0
PYH3_k127_3704460_20 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 - - 0.0000000000000000000000000000000000000000000000002543 176.0
PYH3_k127_3704460_21 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 - - 0.00000000000000000000000000000000000000003749 152.0
PYH3_k127_3704460_22 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000000000135 143.0
PYH3_k127_3704460_23 - - - - 0.000000000000000000000000000000000008605 137.0
PYH3_k127_3704460_24 Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site K02954 - - 0.00000000000000000000000000000002127 126.0
PYH3_k127_3704460_25 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 - - 0.0000000214 55.0
PYH3_k127_3704460_3 Methionine aminopeptidase K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008346 447.0
PYH3_k127_3704460_4 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005727 434.0
PYH3_k127_3704460_5 One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome K02926 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006017 366.0
PYH3_k127_3704460_6 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002421 354.0
PYH3_k127_3704460_7 ribosomal protein L3 K02906 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002735 355.0
PYH3_k127_3704460_8 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009045 303.0
PYH3_k127_3704460_9 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 305.0
PYH3_k127_3711200_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1545.0
PYH3_k127_3711200_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 1.094e-204 638.0
PYH3_k127_3711200_2 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001176 592.0
PYH3_k127_3711200_3 Ammonium Transporter K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 526.0
PYH3_k127_3711200_4 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001034 250.0
PYH3_k127_3711200_5 (Lipo)protein K09860 - - 0.0000000000000000000000000000000000000000000000000000000000002415 214.0
PYH3_k127_37887_0 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 9.78e-213 665.0
PYH3_k127_3803469_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 1.251e-295 911.0
PYH3_k127_3803469_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.15e-286 882.0
PYH3_k127_3803469_10 MotA TolQ ExbB proton channel family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000006012 267.0
PYH3_k127_3803469_11 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005802 252.0
PYH3_k127_3803469_12 peptidyl-prolyl K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000003101 229.0
PYH3_k127_3803469_13 DNA-binding transcription factor activity - - - 0.00000000000000000000000000000000000000000000000000000000000000001651 227.0
PYH3_k127_3803469_14 Belongs to the ATPase B chain family K02109 - - 0.000000000000000000000000000000000000000000000000000000000000006281 219.0
PYH3_k127_3803469_15 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000001344 213.0
PYH3_k127_3803469_16 biotin acetyl-CoA-carboxylase ligase K03524 - 6.3.4.15 0.0000000000000000000000000000000000000000000000000000000002315 209.0
PYH3_k127_3803469_17 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 - - 0.00000000000000000000000000000000000000000000000000000003643 198.0
PYH3_k127_3803469_18 TonB C terminal K03832 - - 0.00000000000000000000000000000000000000000000000000000135 202.0
PYH3_k127_3803469_19 This protein binds to 23S rRNA in the presence of protein L20 K02888 - - 0.000000000000000000000000000000000000000000000000000002968 191.0
PYH3_k127_3803469_2 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 4.828e-207 646.0
PYH3_k127_3803469_20 Nodulation protein S (NodS) - - - 0.00000000000000000000000000000000000000000000000001057 186.0
PYH3_k127_3803469_21 Belongs to the bacterial ribosomal protein bL27 family K02899 - - 0.000000000000000000000000000000000000000000001094 165.0
PYH3_k127_3803469_22 transport protein K03559 - - 0.000000000000000000000000000000000000000007039 157.0
PYH3_k127_3803469_23 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K03585 - - 0.0000000000000000000002562 97.0
PYH3_k127_3803469_24 Protein of unknown function, DUF255 - - - 0.00000000000006467 77.0
PYH3_k127_3803469_3 Involved in the TonB-independent uptake of proteins K03641 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006665 577.0
PYH3_k127_3803469_4 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007884 504.0
PYH3_k127_3803469_5 involved in chromosome partitioning K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 489.0
PYH3_k127_3803469_6 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 - 2.1.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008526 449.0
PYH3_k127_3803469_7 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 441.0
PYH3_k127_3803469_8 Belongs to the ParB family K03497 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004289 428.0
PYH3_k127_3803469_9 Protein-L-isoaspartate(D-aspartate) O-methyltransferase (PCMT) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004051 302.0
PYH3_k127_3813741_0 Potassium uptake protein K03498 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000002819 295.0
PYH3_k127_3813741_1 chemotaxis protein K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000003774 267.0
PYH3_k127_3855605_0 PFAM peptidase M3A and M3B thimet oligopeptidase F K01414 - 3.4.24.70 0.0 1100.0
PYH3_k127_3855605_1 Endonuclease Exonuclease phosphatase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009029 518.0
PYH3_k127_3855605_2 Protein of unknown function (DUF502) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002699 318.0
PYH3_k127_3855605_3 Peptidase s1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009361 308.0
PYH3_k127_3855605_4 Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine K03648 - 3.2.2.27 0.000000000000000000005086 93.0
PYH3_k127_3876394_0 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003864 562.0
PYH3_k127_3876394_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004187 472.0
PYH3_k127_3876394_2 Four helix bundle sensory module for signal transduction - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005787 347.0
PYH3_k127_3876394_3 Ferritin K03594 - 1.16.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 284.0
PYH3_k127_3876394_4 thioesterase K07107 - - 0.0000000000000000000000000000000000000000000000000000000000001412 213.0
PYH3_k127_3876394_5 ankyrin 3, node of Ranvier (ankyrin G) - - - 0.00000002482 61.0
PYH3_k127_3899450_0 Flagellar biosynthetic protein fliR K02421 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001503 411.0
PYH3_k127_3899450_1 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002718 367.0
PYH3_k127_3899450_2 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000511 346.0
PYH3_k127_3899450_3 abc transporter atp-binding protein K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005671 328.0
PYH3_k127_3899450_4 RESPONSE REGULATOR receiver K07288 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000474 291.0
PYH3_k127_4058355_0 Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine K06168 - 2.8.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002793 477.0
PYH3_k127_4058355_1 Belongs to the 'phage' integrase family K03733 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001251 370.0
PYH3_k127_4058355_2 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007447 305.0
PYH3_k127_4058355_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003637 303.0
PYH3_k127_4058355_4 protein conserved in bacteria K09778 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009403 257.0
PYH3_k127_4058355_5 PFAM Fimbrial assembly family protein - - - 0.00000000000000000000000000000000000000000000000000000000000007834 217.0
PYH3_k127_4058355_6 - - - - 0.0000000000000000000000000000000000000000000000000000000003747 206.0
PYH3_k127_412303_0 Involved in the biosynthesis of porphyrin-containing compound - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002298 528.0
PYH3_k127_412303_1 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003819 384.0
PYH3_k127_412303_2 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatC, TatB is part of a receptor directly interacting with Tat signal peptides. TatB may form an oligomeric binding site that transiently accommodates folded Tat precursor proteins before their translocation K03117 - - 0.000000000000000000000000000000000000000000000001021 177.0
PYH3_k127_412303_3 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 - 2.4.99.17 0.00000000000002418 73.0
PYH3_k127_412843_0 Pyridine nucleotide-disulphide oxidoreductase K17229 - 1.8.2.3 6.864e-271 838.0
PYH3_k127_412843_1 Pyridine nucleotide-disulphide oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005783 602.0
PYH3_k127_412843_2 Rieske [2Fe-2S] domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 425.0
PYH3_k127_412843_3 Sulfur oxidation protein SoxY - - - 0.0000000000000000000000000000000000009018 146.0
PYH3_k127_412843_4 superoxide reductase activity K05919,K17227 - 1.15.1.2 0.000000000000000004298 87.0
PYH3_k127_412843_5 - - - - 0.000007146 49.0
PYH3_k127_41335_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 4.13e-276 852.0
PYH3_k127_41335_1 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 5.582e-215 672.0
PYH3_k127_41335_2 Dual-specificity methyltransferase that catalyzes the formation of 5-methyluridine at position 54 (m5U54) in all tRNAs, and that of position 341 (m5U341) in tmRNA (transfer-mRNA) K00557 - 2.1.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 542.0
PYH3_k127_41335_3 Plays a role in the flagellum-specific transport system K02419 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004303 398.0
PYH3_k127_41335_4 RecO N terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005962 331.0
PYH3_k127_41335_5 protein involved in exopolysaccharide biosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000007817 271.0
PYH3_k127_41335_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000000002441 231.0
PYH3_k127_41335_7 phosphatidate phosphatase activity K09474,K19302 - 3.1.3.2,3.6.1.27 0.00000000000000000000000000000000000000000000000000000000000000001339 229.0
PYH3_k127_41335_8 Diacylglycerol kinase K00901 - 2.7.1.107 0.0000000000000000000000000000000000000000000000000000000007969 206.0
PYH3_k127_41335_9 Domain of unknown function (DUF4395) - - - 0.0000000000000000000000000000000001996 136.0
PYH3_k127_4143496_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00367,K00372,K08356 - 1.20.2.1,1.20.9.1,1.7.7.2 0.0 1317.0
PYH3_k127_4143496_1 COG0155 Sulfite reductase, beta subunit (hemoprotein) K00366,K00392 - 1.7.7.1,1.8.7.1 1.192e-301 936.0
PYH3_k127_4143496_2 4Fe-4S dicluster domain K07307 - - 4.42e-285 881.0
PYH3_k127_4143496_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 347.0
PYH3_k127_4143496_4 Histidine kinase K02482,K14986 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000004437 239.0
PYH3_k127_4180128_0 Belongs to the DNA mismatch repair MutS family K03555 - - 4.491e-200 641.0
PYH3_k127_4180128_1 Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006629 396.0
PYH3_k127_4187583_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00833 - 2.6.1.62 1.427e-228 713.0
PYH3_k127_4187583_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002986 563.0
PYH3_k127_4187583_2 peptidylprolyl isomerase K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000669 567.0
PYH3_k127_4187583_3 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 - 2.1.1.199 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000143 504.0
PYH3_k127_4187583_4 - - - - 0.00000000000000000000000000000000000000000000000002917 182.0
PYH3_k127_4187583_6 Belongs to the FPP GGPP synthase family K02523 - 2.5.1.90 0.000000000000000000000000000000000004179 139.0
PYH3_k127_4196177_0 Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02400 - - 0.0 1178.0
PYH3_k127_4196177_1 EAL domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007845 452.0
PYH3_k127_4196177_2 phosphohydrolase (DHH superfamily) K07097 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 381.0
PYH3_k127_4196177_3 Transcriptional regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000001017 226.0
PYH3_k127_4196177_4 Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome K02956 - - 0.00000000000000000000000000000000000000003457 153.0
PYH3_k127_4204910_0 The M ring may be actively involved in energy transduction K02409 - - 9.746e-241 751.0
PYH3_k127_4204910_1 Chorismate mutase prephenate dehydratase K14170 - 4.2.1.51,5.4.99.5 4.874e-210 658.0
PYH3_k127_4204910_2 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 4.046e-206 644.0
PYH3_k127_4204910_3 HAD-superfamily hydrolase, subfamily IIA K02566 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001755 325.0
PYH3_k127_4209321_0 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.434e-252 781.0
PYH3_k127_4209321_1 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 2.071e-207 648.0
PYH3_k127_4209321_2 Phosphoribosylformylglycinamidine cyclo-ligase K01933 - 6.3.3.1 9.561e-198 619.0
PYH3_k127_4209321_3 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine K01778 - 5.1.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001098 429.0
PYH3_k127_4209321_4 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002258 336.0
PYH3_k127_4209321_5 Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine K00797 - 2.5.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000001227 263.0
PYH3_k127_4209321_6 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000000000000000000000000003701 157.0
PYH3_k127_4209321_7 - - - - 0.0000000000000000002629 88.0
PYH3_k127_4209321_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.000000000000002088 76.0
PYH3_k127_4209321_9 Haem-binding domain - - - 0.000002738 50.0
PYH3_k127_421004_0 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 9.583e-272 842.0
PYH3_k127_421004_1 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 1.942e-238 738.0
PYH3_k127_421004_10 metal-binding, possibly nucleic acid-binding protein - - - 0.0000000000000000000000000000000000000000000001895 169.0
PYH3_k127_421004_11 Belongs to the bacterial ribosomal protein bL32 family K02911 - - 0.00000000000000000000001976 99.0
PYH3_k127_421004_2 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000491 590.0
PYH3_k127_421004_3 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 587.0
PYH3_k127_421004_4 Belongs to the DEAD box helicase family K05592 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005666 544.0
PYH3_k127_421004_5 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000000000000000000001812 252.0
PYH3_k127_421004_6 phosphoribosyltransferase K00769 - 2.4.2.22 0.00000000000000000000000000000000000000000000000000000000000000002349 226.0
PYH3_k127_421004_7 membrane K08973 - - 0.0000000000000000000000000000000000000000000000000000000000000001395 222.0
PYH3_k127_421004_8 (HIT) family - - - 0.00000000000000000000000000000000000000000000000000000000005445 206.0
PYH3_k127_421004_9 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000001189 198.0
PYH3_k127_4245655_0 COG2804 Type II secretory pathway ATPase PulE Tfp pilus assembly pathway ATPase PilB K02454,K02652 - - 1.421e-302 934.0
PYH3_k127_4245655_1 COG1450 Type II secretory pathway component PulD K02453 - - 8.129e-236 739.0
PYH3_k127_4245655_2 ATPases associated with a variety of cellular activities - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007035 361.0
PYH3_k127_4245655_3 Pilus assembly protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006979 256.0
PYH3_k127_4245655_6 COG1459 Type II secretory pathway, component PulF K02455 - - 0.0000000000000000000000000000000037 129.0
PYH3_k127_4245655_7 Anaphase-promoting complex, cyclosome, subunit 3 - - - 0.00000000000000000000000000000003709 134.0
PYH3_k127_4359443_0 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 - - 0.0 1011.0
PYH3_k127_4359443_1 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000006466 155.0
PYH3_k127_4359443_2 Diguanylate cyclase with PAS PAC sensor - - - 0.000002602 49.0
PYH3_k127_4367646_0 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00018 - 1.1.1.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002745 501.0
PYH3_k127_4367646_1 PFAM Auxin Efflux Carrier K07088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000171 476.0
PYH3_k127_4367646_2 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000002981 229.0
PYH3_k127_4367646_3 - K12065 - - 0.0000000000000000000000000000000000000000000000000001066 199.0
PYH3_k127_440130_0 Belongs to the GARS family K01945 - 6.3.4.13 4.615e-252 784.0
PYH3_k127_440130_1 Involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 4.415e-196 619.0
PYH3_k127_440130_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000379 478.0
PYH3_k127_440130_3 Uroporphyrinogen-III synthase K01719 - 4.2.1.75 0.00000000000000000000000000000000000000000000000000000000000000001502 230.0
PYH3_k127_440130_4 RDD family - - - 0.000000000000000000000000005808 115.0
PYH3_k127_4410377_0 Belongs to the D-alanine--D-alanine ligase family K01921 - 6.3.2.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 587.0
PYH3_k127_4410377_1 Flagellar Assembly Protein A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002997 455.0
PYH3_k127_4410377_2 Alpha beta hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 332.0
PYH3_k127_4410377_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001974 303.0
PYH3_k127_4410377_4 Mur ligase middle domain K01929 - 6.3.2.10 0.00000000000000000000000002345 108.0
PYH3_k127_4504117_0 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001438 522.0
PYH3_k127_4504117_1 GAF domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009849 399.0
PYH3_k127_4504117_2 Zn-ribbon-containing protein involved in phosphonate metabolism K06193 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001751 304.0
PYH3_k127_4504117_3 cheY-homologous receiver domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000005461 254.0
PYH3_k127_4504117_4 Controls the rotational direction of flagella during chemotaxis K02415 - - 0.000000000000000000000000000000000000000000000000000000000000005758 220.0
PYH3_k127_4504117_5 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000000000000000000000000000003129 195.0
PYH3_k127_4539651_0 Sigma factor PP2C-like phosphatases - - - 1.827e-296 915.0
PYH3_k127_4539651_1 chemotaxis protein K03407 - 2.7.13.3 7.45e-271 857.0
PYH3_k127_4539651_10 protein conserved in bacteria K03269 - 3.6.1.54 0.000000000000000000000000000000000000000000000000000000000000019 222.0
PYH3_k127_4539651_11 Domain of unknown function (DUF1987) - - - 0.00000000000000000000000000000000000000000000000000000000000007874 214.0
PYH3_k127_4539651_12 - - - - 0.000000000000000000000000000000000000000000000000000000000008938 211.0
PYH3_k127_4539651_13 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.000000000000000000000000000000000000000000000000000001346 196.0
PYH3_k127_4539651_14 PFAM EAL domain - - - 0.000000000000000000000000000000000000000000000001407 177.0
PYH3_k127_4539651_2 Belongs to the ClpA ClpB family K03694,K03695 - - 1.641e-221 690.0
PYH3_k127_4539651_3 Belongs to the peptidase M24B family K01262 - 3.4.11.9 6.622e-205 645.0
PYH3_k127_4539651_4 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000233 595.0
PYH3_k127_4539651_5 chemotaxis protein K03415 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000478 517.0
PYH3_k127_4539651_6 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002484 375.0
PYH3_k127_4539651_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001449 317.0
PYH3_k127_4539651_8 chemotaxis protein K03408 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009009 282.0
PYH3_k127_4539651_9 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001117 237.0
PYH3_k127_45880_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 450.0
PYH3_k127_45880_1 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009492 428.0
PYH3_k127_45880_2 AF0941-like - - - 0.000000000000000000000000000000000000000003119 158.0
PYH3_k127_45880_3 beta-lactamase activity K01058,K07126,K12543,K15474 - 3.1.1.32,3.1.1.4 0.0000000000000000000000000000000000000002316 149.0
PYH3_k127_45880_4 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.00000000000000000000000004204 108.0
PYH3_k127_45880_5 Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy- requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins K03832 - - 0.0000000000000000000000001033 116.0
PYH3_k127_45880_6 - - - - 0.0000000000000000000000003201 110.0
PYH3_k127_4821311_0 STAS domain K03321 - - 0.0 1065.0
PYH3_k127_4821311_1 threonine synthase K01733 - 4.2.3.1 2.11e-280 865.0
PYH3_k127_4821311_2 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005304 535.0
PYH3_k127_4821311_3 polyphosphate kinase K22468 - 2.7.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002632 466.0
PYH3_k127_4821311_4 Highly conserved protein containing a thioredoxin domain K06888 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002069 409.0
PYH3_k127_4974502_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00990 - 2.7.7.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004093 466.0
PYH3_k127_4974502_1 TIGRFAM diguanylate cyclase (GGDEF) domain K13069,K13590,K18967 GO:0003674,GO:0003824,GO:0005488,GO:0008144,GO:0016740,GO:0016772,GO:0016779,GO:0019825,GO:0020037,GO:0036094,GO:0042165,GO:0043167,GO:0043169,GO:0046906,GO:0048037,GO:0052621,GO:0070025,GO:0097159,GO:1901363 2.7.7.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001525 423.0
PYH3_k127_5007369_0 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 0.0 1074.0
PYH3_k127_5007369_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002259 376.0
PYH3_k127_5007369_2 His Kinase A (phosphoacceptor) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003194 331.0
PYH3_k127_5007369_3 Desulfoferrodoxin ferrous iron-binding K05919 - 1.15.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005693 282.0
PYH3_k127_5011576_0 Belongs to the DegT DnrJ EryC1 family K15895 - 2.6.1.92 4.786e-210 656.0
PYH3_k127_5011576_1 7TMR-DISM extracellular 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005731 536.0
PYH3_k127_5011576_2 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 - 6.3.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003276 431.0
PYH3_k127_5011576_3 hmm pf04305 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002105 241.0
PYH3_k127_5011576_4 Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) K00912 - 2.7.1.130 0.000000000000000000000000000000000000000000008458 165.0
PYH3_k127_503782_0 cheY-homologous receiver domain K03412,K03413 - 3.1.1.61,3.5.1.44 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002367 396.0
PYH3_k127_503782_1 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001712 363.0
PYH3_k127_503782_2 DnaJ domain protein K05801 - - 0.000000002985 57.0
PYH3_k127_513326_0 twitching motility protein K02669 - - 5.143e-217 677.0
PYH3_k127_513326_1 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003045 501.0
PYH3_k127_513326_2 Domain of unknown function (DUF4105) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003651 421.0
PYH3_k127_513326_3 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 - - 0.00000000000000000000000000004804 116.0
PYH3_k127_5144950_0 ATP-dependent DNA helicase K03655 - 3.6.4.12 7.193e-219 687.0
PYH3_k127_5144950_1 Peptidase, M16 - - - 8.282e-209 655.0
PYH3_k127_5144950_2 Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2) K11784 - 1.21.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005232 579.0
PYH3_k127_5226490_0 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1146.0
PYH3_k127_5226490_1 IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins K02520 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005438 330.0
PYH3_k127_5226490_2 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 - - 0.0000000000000000000000000000000000000000000000000000000000002859 213.0
PYH3_k127_5226490_3 Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant K03465 - 2.1.1.148 0.00000000000000000000000000000000000000000000008947 169.0
PYH3_k127_5226490_4 Belongs to the bacterial ribosomal protein bL35 family K02916 - - 0.0000000000000000000000000001041 119.0
PYH3_k127_5245433_0 fumarate reductase, flavoprotein subunit K00239 - 1.3.5.1,1.3.5.4 0.0 1061.0
PYH3_k127_5245433_1 Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs K06176 - 5.4.99.27 1.29e-199 625.0
PYH3_k127_5245433_2 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 542.0
PYH3_k127_5245433_3 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 413.0
PYH3_k127_5245433_4 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007623 407.0
PYH3_k127_5245433_5 Diguanylate cyclase, GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003101 409.0
PYH3_k127_5245433_6 - - - - 0.00000000000000000000000000000000000000000000000000000001179 203.0
PYH3_k127_5258455_0 AAA domain - - - 2.488e-237 761.0
PYH3_k127_5258455_1 Heat shock 70 kDa protein K04043 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001028 561.0
PYH3_k127_5258455_2 Transglutaminase-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000864 351.0
PYH3_k127_5258455_3 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000003806 230.0
PYH3_k127_5258455_4 Protein of unknown function (DUF420) K08976 - - 0.00000000000000007001 81.0
PYH3_k127_5302530_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 0.0 1403.0
PYH3_k127_5302530_1 Biotin carboxylase K01959,K01961 - 6.3.4.14,6.4.1.1,6.4.1.2 1.16e-295 909.0
PYH3_k127_5302530_10 protein transport K03210 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0031522,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000006154 98.0
PYH3_k127_5302530_2 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03072 - - 1.517e-272 846.0
PYH3_k127_5302530_3 Diguanylate cyclase - - - 4.075e-240 750.0
PYH3_k127_5302530_4 apolipoprotein N-acyltransferase K03820 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 602.0
PYH3_k127_5302530_5 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001555 579.0
PYH3_k127_5302530_6 folylpolyglutamate synthase K11754 - 6.3.2.12,6.3.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001314 557.0
PYH3_k127_5302530_7 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA K03074 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 552.0
PYH3_k127_5302530_8 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007763 387.0
PYH3_k127_5302530_9 Lipopolysaccharide-assembly - - - 0.000000000000000000000000000000000000000000000000000000000000006612 220.0
PYH3_k127_5307319_0 hydrogenase (NiFe) small subunit HydA K05927 - 1.12.5.1 0.0 1243.0
PYH3_k127_5307319_1 Belongs to the NiFe NiFeSe hydrogenase large subunit family K05922 - 1.12.5.1 1.037e-311 962.0
PYH3_k127_5307319_2 Hydrogenase-4, component G K14090 - - 8.685e-212 661.0
PYH3_k127_5307319_3 NADH dehydrogenase K14087 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004692 415.0
PYH3_k127_5307319_4 NADH ubiquinone oxidoreductase, 20 Kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004569 334.0
PYH3_k127_5307319_5 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K00338,K14091 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000002332 247.0
PYH3_k127_5307319_6 Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide K04656 - - 0.000000000000000000000000000000000000000000000000000000000000000003391 232.0
PYH3_k127_5307319_7 Hydrogenase maturation protease K03605 - - 0.00000000000000000000000000000000000000000000000006061 184.0
PYH3_k127_5307319_8 Respiratory-chain NADH dehydrogenase, 30 Kd subunit - - - 0.000000000000000000000002979 105.0
PYH3_k127_5327206_0 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 1.787e-223 698.0
PYH3_k127_5327206_1 that it carries out the mismatch recognition step. This protein has a weak ATPase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002584 355.0
PYH3_k127_5327206_2 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001659 292.0
PYH3_k127_5327206_3 Pfam Methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000177 246.0
PYH3_k127_5332456_0 MiaB-like tRNA modifying enzyme - - - 1.219e-226 706.0
PYH3_k127_5332456_1 Belongs to the AAA ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005242 254.0
PYH3_k127_5332456_2 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000004379 199.0
PYH3_k127_53573_0 4fe-4s ferredoxin, iron-sulfur binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 555.0
PYH3_k127_53573_1 GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004894 383.0
PYH3_k127_53573_2 component of anaerobic - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 349.0
PYH3_k127_53573_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002403 273.0
PYH3_k127_53573_4 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) - - - 0.000000000000000000000000000000000000000000000000000000000088 206.0
PYH3_k127_53573_5 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family - - - 0.00000000000000000000000005896 106.0
PYH3_k127_54304_0 DNA helicase K03657 - 3.6.4.12 0.0 1197.0
PYH3_k127_54304_1 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004124 531.0
PYH3_k127_54304_10 Global regulator protein family - - - 0.000008327 50.0
PYH3_k127_54304_2 Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs K03177 - 5.4.99.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 447.0
PYH3_k127_54304_3 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 - 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002449 422.0
PYH3_k127_54304_4 Belongs to the RNA methyltransferase TrmD family K00554 - 2.1.1.228 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 415.0
PYH3_k127_54304_5 Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene K03664 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001706 272.0
PYH3_k127_54304_6 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002667 252.0
PYH3_k127_54304_7 Branched-chain amino acid aminotransferase K02619 - 4.1.3.38 0.0000000000000000000000000000000000000003589 150.0
PYH3_k127_54304_8 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000006669 130.0
PYH3_k127_54304_9 An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes K02860 - - 0.000000000000000000000000000009006 119.0
PYH3_k127_5431082_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 3.571e-268 833.0
PYH3_k127_5431082_1 Arginosuccinate synthase K00566 - 2.8.1.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002766 530.0
PYH3_k127_5431082_2 Cytochrome C biogenesis protein transmembrane region K09792 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001697 354.0
PYH3_k127_5431082_3 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000001474 234.0
PYH3_k127_5431082_4 - - - - 0.0000000000000000000000000000000001147 136.0
PYH3_k127_5431082_6 Heavy-metal-associated domain K17686 - 3.6.3.54 0.000001232 53.0
PYH3_k127_5460064_0 Belongs to the glycosyl hydrolase 57 family K22451 - 2.4.1.25 0.0 1042.0
PYH3_k127_5460064_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 4.635e-262 814.0
PYH3_k127_5460064_2 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 - 2.4.1.21 4.197e-200 634.0
PYH3_k127_5460064_3 COGs COG1940 Transcriptional regulator sugar kinase K00845 - 2.7.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 366.0
PYH3_k127_5460064_4 PFAM Galactose-1-phosphate uridyl transferase K00965 - 2.7.7.12 0.00000000000000000000000000000000000000000000000000000000000006918 226.0
PYH3_k127_5460064_5 Belongs to the glycosyl hydrolase 57 family - - - 0.0000000000000000000000000000000000000000000001118 171.0
PYH3_k127_5465501_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004622 495.0
PYH3_k127_5465501_1 Belongs to the peptidase S26 family K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009665 478.0
PYH3_k127_5465501_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001447 312.0
PYH3_k127_5465501_3 ribose 5-phosphate isomerase K01808 - 5.3.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000007116 278.0
PYH3_k127_5465501_4 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000009168 195.0
PYH3_k127_5465501_5 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000001265 196.0
PYH3_k127_5465501_6 - - - - 0.0000000000000000000000000000000000000000000000000004545 185.0
PYH3_k127_5473508_0 Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA K01610 - 4.1.1.49 2.066e-316 972.0
PYH3_k127_5473508_1 glutamine synthetase K01915 - 6.3.1.2 9.89e-308 945.0
PYH3_k127_5473508_10 Prokaryotic N-terminal methylation motif - - - 0.0003158 49.0
PYH3_k127_5473508_2 peptidase U32 family K08303 - - 4.118e-262 810.0
PYH3_k127_5473508_3 histidinol phosphate phosphatase K04486 - 3.1.3.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001081 423.0
PYH3_k127_5473508_4 Protein of unknown function DUF89 K09116 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001759 325.0
PYH3_k127_5473508_5 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 312.0
PYH3_k127_5473508_6 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001024 292.0
PYH3_k127_5473508_7 Protein of unknown function (DUF3972) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001023 244.0
PYH3_k127_5473508_8 Prokaryotic N-terminal methylation motif K02456 - - 0.000000000000000000000000000000000000000000000002494 177.0
PYH3_k127_5473508_9 TIGRFAM prepilin-type N-terminal cleavage methylation domain K02456 - - 0.0000000000000000000000000001699 116.0
PYH3_k127_55162_0 chemotaxis protein K03407 - 2.7.13.3 4.645e-215 672.0
PYH3_k127_55162_1 Heterodisulfide reductase subunit B K00241 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000359 576.0
PYH3_k127_55162_10 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240,K00245 - 1.3.5.1,1.3.5.4 0.000000000000000000000000000000000000000000242 158.0
PYH3_k127_55162_11 Uncharacterised ACR, YagE family COG1723 - - - 0.0000000000000000000000000000000000000002256 159.0
PYH3_k127_55162_12 CHAD - - - 0.0000005852 60.0
PYH3_k127_55162_2 catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins) by CheR K03412 - 3.1.1.61,3.5.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 577.0
PYH3_k127_55162_3 phosphorelay signal transduction system K01768,K07315 - 3.1.3.3,4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005774 486.0
PYH3_k127_55162_4 GGDEF domain - GO:0003674,GO:0003824,GO:0008081,GO:0016787,GO:0016788,GO:0042578,GO:0071111 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004267 423.0
PYH3_k127_55162_5 PFAM ATP-binding region, ATPase domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008393 312.0
PYH3_k127_55162_6 protein-glutamate O-methyltransferase activity K00575 - 2.1.1.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 293.0
PYH3_k127_55162_7 Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis K03411 - 3.5.1.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000142 256.0
PYH3_k127_55162_8 Histidine kinase K13040 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000002389 274.0
PYH3_k127_55162_9 His Kinase A (phosphoacceptor) domain K10125 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000003212 202.0
PYH3_k127_5563237_0 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 4.406e-213 664.0
PYH3_k127_5563237_1 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003589 495.0
PYH3_k127_558341_0 Belongs to the dGTPase family. Type 2 subfamily K01129 - 3.1.5.1 6.908e-211 658.0
PYH3_k127_558341_1 PFAM HI0933 family protein K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000688 387.0
PYH3_k127_558341_2 - - - - 0.000000000000000000000000000000000000000000000002179 188.0
PYH3_k127_558341_3 - - - - 0.000000000000000000000000000004415 124.0
PYH3_k127_5597455_0 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005926 478.0
PYH3_k127_5597455_1 Major facilitator superfamily K03446 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 366.0
PYH3_k127_5597455_2 endoribonuclease L-PSP K09022 - 3.5.99.10 0.00000000000000000000000000000000000000000000000000000000001758 209.0
PYH3_k127_5597455_3 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000000000000000006604 200.0
PYH3_k127_5641236_0 ATP-dependent DNA helicase RecQ K03654 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003104 589.0
PYH3_k127_5641236_1 Putative diguanylate phosphodiesterase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004236 559.0
PYH3_k127_5641236_2 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000004015 295.0
PYH3_k127_5793169_0 chemotaxis protein K03406 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004591 301.0
PYH3_k127_5793169_1 MORN repeat variant - - - 0.0000004717 55.0
PYH3_k127_5795867_0 Belongs to the NAD(P)-dependent epimerase dehydratase family. dTDP-glucose dehydratase subfamily K01710 - 4.2.1.46 9.166e-211 656.0
PYH3_k127_5795867_1 Alginate O-acetylation protein - - - 2.173e-207 655.0
PYH3_k127_5795867_10 - - - - 0.000000000005378 77.0
PYH3_k127_5795867_2 Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis K00973 - 2.7.7.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003004 574.0
PYH3_k127_5795867_3 involved in cell wall biogenesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 543.0
PYH3_k127_5795867_4 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002403 503.0
PYH3_k127_5795867_5 involved in cell wall biogenesis - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009641 482.0
PYH3_k127_5795867_6 Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4- hexulose to yield dTDP-L-rhamnose K00067 - 1.1.1.133 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009428 470.0
PYH3_k127_5795867_7 Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose K01790 - 5.1.3.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008723 363.0
PYH3_k127_5795867_8 PFAM O-Antigen K02847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002851 370.0
PYH3_k127_5795867_9 Protein of unknown function (DUF535) K09824 - - 0.0000000000000000000000000000009949 132.0
PYH3_k127_5905_0 Domain of Unknown Function (DUF748) - - - 0.0 1192.0
PYH3_k127_5905_1 Belongs to the UPF0324 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005268 299.0
PYH3_k127_5905_2 Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides K00526 - 1.17.4.1 0.00000000000000000000000000000000000000000000000000000000000000000001963 232.0
PYH3_k127_592673_0 Thiol disulfide interchange protein K04084 - 1.8.1.8 9.771e-278 865.0
PYH3_k127_592673_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000282 552.0
PYH3_k127_592673_2 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005983 522.0
PYH3_k127_592673_3 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004884 281.0
PYH3_k127_592673_4 Pyridine nucleotide-disulphide oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000001385 241.0
PYH3_k127_592673_5 Protein of unknown function, DUF255 - - - 0.000000000000000000000000000000000000000000000000000008899 191.0
PYH3_k127_592673_6 Chorismate mutase K04782 - 4.2.99.21 0.00000000000000000000000000000000000000000003981 162.0
PYH3_k127_592673_7 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000003423 154.0
PYH3_k127_592673_8 cytochrome c class I - - - 0.000000000000000000000000000000006981 134.0
PYH3_k127_599888_0 COG1070 Sugar (pentulose and hexulose) K11216 - 2.7.1.189 9.972e-262 812.0
PYH3_k127_599888_1 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K00169 - 1.2.7.1 1.807e-236 734.0
PYH3_k127_599888_2 pyruvate ferredoxin oxidoreductase K00170 - 1.2.7.1 5.7e-201 626.0
PYH3_k127_599888_3 pyruvate ferredoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 354.0
PYH3_k127_599888_4 pyruvate ferredoxin oxidoreductase K00171 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008371 269.0
PYH3_k127_599888_5 Hydrolase K01091 - 3.1.3.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000001532 267.0
PYH3_k127_599888_6 Class II Aldolase and Adducin N-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001163 260.0
PYH3_k127_599888_7 Antibiotic biosynthesis monooxygenase - - - 0.0000000000000000000000000000000000000000000000000004481 186.0
PYH3_k127_599888_8 Abc transporter K02035 - - 0.00000000000000000000000005219 107.0
PYH3_k127_6002966_0 Guanosine pentaphosphate phosphohydrolase K01524 - 3.6.1.11,3.6.1.40 9.633e-218 684.0
PYH3_k127_6002966_1 Histidine kinase K02484 - 2.7.13.3 4.187e-213 668.0
PYH3_k127_6002966_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 - 2.5.1.72 2.768e-196 614.0
PYH3_k127_6002966_3 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001461 441.0
PYH3_k127_6002966_4 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 344.0
PYH3_k127_6002966_5 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009743 318.0
PYH3_k127_6002966_6 Ferredoxin K05337 - - 0.000000000000000000000000000000000000000000003047 164.0
PYH3_k127_6002966_7 Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane K07277 - - 0.000000000000000000000000000000000000006486 147.0
PYH3_k127_6002966_8 dihydroneopterin aldolase K01633 - 1.13.11.81,4.1.2.25,5.1.99.8 0.0000000000000000000000000000000003239 134.0
PYH3_k127_6033978_0 DNA processing protein K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004503 378.0
PYH3_k127_6033978_1 Divergent polysaccharide deacetylase K09798 - - 0.00000000000000000000000000000000000000000000000000000000000000163 221.0
PYH3_k127_6033978_2 cytochrome C oxidoreductase subunit B - - - 0.000000000000000000000000000000000000000000000000000003183 191.0
PYH3_k127_6033978_3 Sulfite dehydrogenase (Cytochrome) subunit SorA apoprotein K07147 - - 0.0000000000000000000000000000000000000000000000001226 177.0
PYH3_k127_6134508_0 ATPase (AAA - - - 0.0 1047.0
PYH3_k127_6134508_1 COG0436 Aspartate tyrosine aromatic aminotransferase K10907 - - 1.146e-205 644.0
PYH3_k127_6134508_2 Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5'-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009125 517.0
PYH3_k127_6134508_3 chemotaxis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001752 459.0
PYH3_k127_6134508_4 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003153 334.0
PYH3_k127_6134508_5 - - - - 0.00000000000000000000000000000000000001122 150.0
PYH3_k127_6148251_0 acetolactate synthase K01652 - 2.2.1.6 0.0 1075.0
PYH3_k127_6148251_1 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009364 486.0
PYH3_k127_6148251_2 chemotaxis protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000439 396.0
PYH3_k127_6148251_3 acetolactate synthase K01653 - 2.2.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000008898 276.0
PYH3_k127_6148251_4 Cytochrome c - - - 0.0000000000000000000000000000000000000000000000000001784 188.0
PYH3_k127_6156865_0 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 - - 0.0 1106.0
PYH3_k127_6156865_1 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00412 - - 3.342e-262 809.0
PYH3_k127_6156865_10 PepSY-associated TM region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003469 307.0
PYH3_k127_6156865_11 Pfam Transposase IS66 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 295.0
PYH3_k127_6156865_12 Histidine kinase K03406,K05875,K07647 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000002055 269.0
PYH3_k127_6156865_13 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.00000000000000000000000000000000000000000000004636 170.0
PYH3_k127_6156865_2 TonB dependent receptor - - - 1.311e-247 782.0
PYH3_k127_6156865_3 ubiquinol cytochrome c oxidoreductase, cytochrome c1 K00413 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004875 492.0
PYH3_k127_6156865_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009539 418.0
PYH3_k127_6156865_5 COG0790 FOG TPR repeat, SEL1 subfamily K07126 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001145 355.0
PYH3_k127_6156865_6 riboflavin synthase alpha K00793 - 2.5.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009443 352.0
PYH3_k127_6156865_7 Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002073 347.0
PYH3_k127_6156865_8 Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis K00411 - 1.10.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002754 336.0
PYH3_k127_6156865_9 Protein involved in meta-pathway of phenol degradation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005848 313.0
PYH3_k127_6169960_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0 1090.0
PYH3_k127_6169960_1 Belongs to the flagella basal body rod proteins family K02392 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001877 486.0
PYH3_k127_6169960_2 flagellar basal body K02392 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006605 454.0
PYH3_k127_6169960_3 Histidine kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005496 368.0
PYH3_k127_6169960_4 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000027 301.0
PYH3_k127_6169960_5 - - - - 0.0000000000000000000000000000000000000000000003277 169.0
PYH3_k127_6169960_6 COG0841 Cation multidrug efflux pump - - - 0.000000000000005082 76.0
PYH3_k127_6172919_0 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004284 489.0
PYH3_k127_6172919_1 Superoxide dismutase K04564 - 1.15.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006213 307.0
PYH3_k127_6172919_2 COG1648 Siroheme synthase (precorrin-2 oxidase ferrochelatase domain) K02304 - 1.3.1.76,4.99.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 287.0
PYH3_k127_6172919_3 COG0474 Cation transport ATPase K01537 - 3.6.3.8 0.000000000000000000000001437 105.0
PYH3_k127_6181486_0 Belongs to the Orn Lys Arg decarboxylase class-II family. NspC subfamily K13747 - 4.1.1.96 2.821e-226 704.0
PYH3_k127_6181486_1 Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) K00773 - 2.4.2.29 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001719 492.0
PYH3_k127_6181486_2 protein involved in exopolysaccharide biosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004059 500.0
PYH3_k127_6181486_3 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 - 2.6.99.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002211 400.0
PYH3_k127_6181486_4 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003995 366.0
PYH3_k127_6181486_5 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008784 357.0
PYH3_k127_6181486_6 PFAM AMMECR1 domain protein K09141 - - 0.0000000000000000000000000000000000000000000000000000000000000000000004768 241.0
PYH3_k127_6181486_7 Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) K00097 - 1.1.1.262 0.000000000007023 66.0
PYH3_k127_6187744_0 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 9.561e-198 619.0
PYH3_k127_6187744_1 Major facilitator superfamily K03762 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004319 576.0
PYH3_k127_6187744_2 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000001795 218.0
PYH3_k127_6211103_0 GAF domain K01768 - 4.6.1.1 0.0 1605.0
PYH3_k127_6211103_1 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 1.367e-264 818.0
PYH3_k127_6211103_10 PhoQ Sensor - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004221 344.0
PYH3_k127_6211103_11 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005322 336.0
PYH3_k127_6211103_12 COG0491 Zn-dependent hydrolases, including glyoxylases - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002893 332.0
PYH3_k127_6211103_13 COG2199 FOG GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004712 332.0
PYH3_k127_6211103_14 Thioredoxin-like - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000005453 287.0
PYH3_k127_6211103_15 thioesterase K02614 - - 0.00000000000000000000000000000000000000000000000000000000000000003238 226.0
PYH3_k127_6211103_16 Belongs to the 5-formyltetrahydrofolate cyclo-ligase family K01934 - 6.3.3.2 0.00000000000000000000000000000000000000000000000000000001889 203.0
PYH3_k127_6211103_17 Cytochrome c family protein - - - 0.000000000000000000000000000000000000005935 152.0
PYH3_k127_6211103_18 GGDEF domain - - - 0.0000000000000000000000000000000002251 135.0
PYH3_k127_6211103_2 Endoribonuclease that initiates mRNA decay K18682 - - 5.86e-246 768.0
PYH3_k127_6211103_3 Catalyzes carboxymethyl transfer from carboxy-S- adenosyl-L-methionine (Cx-SAM) to 5-hydroxyuridine (ho5U) to form 5-carboxymethoxyuridine (cmo5U) at position 34 in tRNAs K15257 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 546.0
PYH3_k127_6211103_4 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). Interaction with SRP-RNC leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03110 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009906 536.0
PYH3_k127_6211103_5 Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 442.0
PYH3_k127_6211103_6 ABC-type transport system involved in resistance to organic solvents permease component K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000414 434.0
PYH3_k127_6211103_7 Reversible hydration of carbon dioxide K01673 - 4.2.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001213 381.0
PYH3_k127_6211103_8 COG3437 Response regulator containing a CheY-like receiver domain and an HD-GYP domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002675 402.0
PYH3_k127_6211103_9 hmm pf04305 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006267 362.0
PYH3_k127_6214399_0 DNA helicase K03657 - 3.6.4.12 0.0 1250.0
PYH3_k127_6214399_1 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454,K02652 - - 0.0 1041.0
PYH3_k127_6214399_2 Type II secretion system K02455,K12278 - - 1.848e-212 665.0
PYH3_k127_6240010_0 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K01139 - 2.7.6.5,3.1.7.2 0.0 1105.0
PYH3_k127_6240010_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 2.953e-206 645.0
PYH3_k127_6240010_2 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001691 563.0
PYH3_k127_6240010_3 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004169 432.0
PYH3_k127_6240010_4 Peptidase s1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004372 288.0
PYH3_k127_6240010_5 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.0000000000000000000000000008584 113.0
PYH3_k127_6301966_0 Belongs to the prokaryotic molybdopterin-containing oxidoreductase family K00123 - 1.17.1.9 0.0 1288.0
PYH3_k127_6301966_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 3.358e-276 851.0
PYH3_k127_6301966_10 Histidine biosynthesis bifunctional protein hisIE K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001842 417.0
PYH3_k127_6301966_11 Short-chain dehydrogenase reductase sdr - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009322 380.0
PYH3_k127_6301966_12 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009121 330.0
PYH3_k127_6301966_13 bacterioferritin comigratory protein K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001825 292.0
PYH3_k127_6301966_14 S1 domain K00243 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001752 278.0
PYH3_k127_6301966_15 COG2346 Truncated hemoglobins K06886 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001615 276.0
PYH3_k127_6301966_16 Belongs to the thioredoxin family K03671 - - 0.0000000000000000000000000000000000000000000000000000000001949 203.0
PYH3_k127_6301966_17 Belongs to the UPF0102 family K07460 - - 0.00000000000000000000000000000000000000000000000002018 180.0
PYH3_k127_6301966_18 Protein of unknown function (DUF2393) - - - 0.00000000000000000000000000000000000000000000000009673 182.0
PYH3_k127_6301966_19 Protein of unknown function (DUF2393) - - - 0.00000000000004046 79.0
PYH3_k127_6301966_2 Belongs to the aldehyde dehydrogenase family - - - 8.345e-258 799.0
PYH3_k127_6301966_3 Protein of unknown function (DUF3373) - - - 1.814e-237 743.0
PYH3_k127_6301966_4 COG0330 Membrane protease subunits stomatin prohibitin homologs - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004717 591.0
PYH3_k127_6301966_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 587.0
PYH3_k127_6301966_6 Radical SAM protein K07139 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003909 556.0
PYH3_k127_6301966_7 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008206 546.0
PYH3_k127_6301966_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001321 472.0
PYH3_k127_6301966_9 Belongs to the universal ribosomal protein uS2 family K02967 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005706 461.0
PYH3_k127_6317043_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1242.0
PYH3_k127_6317043_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001744 522.0
PYH3_k127_6317043_2 Phosphoesterase K07095 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001529 299.0
PYH3_k127_6317043_3 AMMECR1 K09141 - - 0.0000001544 53.0
PYH3_k127_6322341_0 PFAM Pyridine nucleotide-disulphide oxidoreductase, FAD NAD(P)-binding domain, pyridine nucleotide-disulfide oxidoreductase dimerization region, FAD-dependent pyridine nucleotide-disulfide oxidoreductase K00382 - 1.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005939 563.0
PYH3_k127_6322341_1 Putative diguanylate phosphodiesterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006979 400.0
PYH3_k127_6322341_2 Response regulator receiver - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004218 336.0
PYH3_k127_6322341_3 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003459 308.0
PYH3_k127_6322341_4 Phage integrase family - - - 0.00000000000000000000000000000001065 145.0
PYH3_k127_6322341_5 Cytochrome C' - - - 0.000000000000000000000000001515 111.0
PYH3_k127_6322341_6 - - - - 0.00000000000000000000000001057 110.0
PYH3_k127_6334906_0 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 2.4e-248 769.0
PYH3_k127_6334906_1 Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release K02863 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003185 424.0
PYH3_k127_6334906_2 Participates in transcription elongation, termination and antitermination K02601 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001489 340.0
PYH3_k127_6334906_3 Belongs to the UPF0246 family K09861 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004131 332.0
PYH3_k127_6334906_4 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000004976 273.0
PYH3_k127_6334906_5 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003294 272.0
PYH3_k127_6334906_6 Sodium calcium exchanger membrane K07300 - - 0.00000000000000000000000000000000000000000000000000000000000002475 215.0
PYH3_k127_6334906_7 Belongs to the bacterial ribosomal protein bL33 family K02913 - - 0.00000000000000000000000173 102.0
PYH3_k127_6334906_8 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000004132 98.0
PYH3_k127_6334906_9 Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation K03073 - - 0.00000000000000000004427 91.0
PYH3_k127_6346055_0 TonB dependent receptor K16092 - - 8.226e-199 636.0
PYH3_k127_6346055_1 Periplasmic binding protein K02016 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009577 349.0
PYH3_k127_6346055_2 AAA domain, putative AbiEii toxin, Type IV TA system K02013 - 3.6.3.34 0.000000000001734 75.0
PYH3_k127_6357593_0 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 1.873e-276 852.0
PYH3_k127_6357593_1 Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000103 387.0
PYH3_k127_6357593_2 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.0000000000000000000000000000000000000000000000000000000000000001634 224.0
PYH3_k127_6357593_3 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.00000001656 56.0
PYH3_k127_6361406_0 transporter of a GTP-driven Fe(2 ) uptake system K04759 - - 0.0 1155.0
PYH3_k127_6361406_1 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 6.263e-279 864.0
PYH3_k127_6361406_11 Cupin - - - 0.000000000000000000000000000000000000000000000000000003539 194.0
PYH3_k127_6361406_12 SEC-C motif K09858 - - 0.000000000000000000000000000000000000000000000000003984 184.0
PYH3_k127_6361406_13 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.0000000000000000003192 95.0
PYH3_k127_6361406_14 Fe2 transport system protein A K04758 - - 0.000000000000009717 77.0
PYH3_k127_6361406_2 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 4.748e-268 827.0
PYH3_k127_6361406_3 PFAM EAL domain - - - 1.366e-227 716.0
PYH3_k127_6361406_4 DNA recombination protein K09760 - - 1.693e-222 696.0
PYH3_k127_6361406_5 Histidine kinase K02484 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003254 541.0
PYH3_k127_6361406_6 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003923 448.0
PYH3_k127_6361406_7 Provides the (R)-glutamate required for cell wall biosynthesis K01776 GO:0003674,GO:0005488,GO:0005515,GO:0042802 5.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001348 443.0
PYH3_k127_6361406_8 involved in molybdopterin and thiamine biosynthesis family 1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002992 391.0
PYH3_k127_6361406_9 response regulator K02483 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 387.0
PYH3_k127_6382143_0 COG2256 ATPase related to the helicase subunit of the Holliday junction resolvase K07478 - - 3.894e-221 689.0
PYH3_k127_6382143_1 Belongs to the pseudouridine synthase RsuA family K06178 - 5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009811 511.0
PYH3_k127_6382143_2 Uncharacterised protein family UPF0047 - - - 0.000000000000000000000000000000000000000000000000000000000000000000002765 236.0
PYH3_k127_6382143_3 PFAM phosphoesterase, PA-phosphatase related - - - 0.0000000000000000000000000000000001041 141.0
PYH3_k127_6382143_4 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000904 77.0
PYH3_k127_6382143_5 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00004802 47.0
PYH3_k127_6438499_0 Aminotransferase K14261 - - 4.365e-258 796.0
PYH3_k127_6438499_1 homoserine dehydrogenase K00003 - 1.1.1.3 8.371e-220 687.0
PYH3_k127_6438499_10 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000000000000000000000002776 215.0
PYH3_k127_6438499_11 ribosomal protein L17 K02879 - - 0.000000000000000000000000000000000000000000000000000000000002383 209.0
PYH3_k127_6438499_12 Nitrogen fixation protein NifU - - - 0.0000000000000000000000000000000000000000000000006041 176.0
PYH3_k127_6438499_15 Binds the 23S rRNA K02909 - - 0.000000000000000000000000000000003794 129.0
PYH3_k127_6438499_16 molybdopterin biosynthesis K03750 - 2.10.1.1 0.0000000000000000002832 89.0
PYH3_k127_6438499_17 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.0000000000000005039 77.0
PYH3_k127_6438499_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 605.0
PYH3_k127_6438499_3 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 - 2.1.1.198 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005433 451.0
PYH3_k127_6438499_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006984 402.0
PYH3_k127_6438499_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001384 391.0
PYH3_k127_6438499_6 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 314.0
PYH3_k127_6438499_7 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001983 250.0
PYH3_k127_6438499_8 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002816 252.0
PYH3_k127_6438499_9 Protein conserved in bacteria - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002974 247.0
PYH3_k127_6450015_0 flagellar hook-associated protein K02396 - - 9.297e-262 821.0
PYH3_k127_6450015_1 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 7.742e-237 736.0
PYH3_k127_6450015_10 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000003848 233.0
PYH3_k127_6450015_11 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.000000000000000000000000000000000000000000000000000000000000000003537 228.0
PYH3_k127_6450015_12 - - - - 0.0000000000000000000000000000000000000000000000000000000000001593 214.0
PYH3_k127_6450015_13 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 - - 0.000000000000000000000000000000000000000000003612 164.0
PYH3_k127_6450015_14 Rod binding protein - - - 0.000000000000000000000000000000000000000000006634 164.0
PYH3_k127_6450015_15 Anti-sigma-28 factor, FlgM - - - 0.0000000000000000000000000009203 113.0
PYH3_k127_6450015_19 L-threonylcarbamoyladenylate synthase - - - 0.0001951 44.0
PYH3_k127_6450015_2 Glutathionylspermidine synthase - - - 6.303e-224 698.0
PYH3_k127_6450015_3 Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation K02394 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001218 558.0
PYH3_k127_6450015_4 COG1173 ABC-type dipeptide oligopeptide nickel transport systems permease components K02034,K12370 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003817 437.0
PYH3_k127_6450015_5 COG0847 DNA polymerase III epsilon subunit and related 3'-5' K02342,K10857 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 348.0
PYH3_k127_6450015_6 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001961 316.0
PYH3_k127_6450015_7 Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism K03111 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 310.0
PYH3_k127_6450015_8 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000009182 276.0
PYH3_k127_6450015_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001049 262.0
PYH3_k127_6494769_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005785 522.0
PYH3_k127_6494769_1 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002349 516.0
PYH3_k127_6494769_2 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001603 284.0
PYH3_k127_6494769_3 Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA K00783 - 2.1.1.177 0.0000000000000000000000000000000000000000000000000000000000000000000000000002346 258.0
PYH3_k127_6494769_4 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000000000000000000000000000005167 197.0
PYH3_k127_6494769_5 Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000000000000000000006771 164.0
PYH3_k127_6494769_6 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05540 - - 0.0000000000000000000000000000000000000000008831 157.0
PYH3_k127_6524411_0 glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009958 592.0
PYH3_k127_6524411_1 Diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000003688 205.0
PYH3_k127_6529430_0 Belongs to the IlvD Edd family K01687 - 4.2.1.9 1.199e-259 801.0
PYH3_k127_6529430_1 phosphoserine phosphatase activity - - - 0.000000000000000001204 91.0
PYH3_k127_6581703_0 AsmA-like C-terminal region - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001065 520.0
PYH3_k127_6581703_1 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001714 392.0
PYH3_k127_6584867_0 5-methyltetrahydrofolate--homocysteine methyltransferase K00548 - 2.1.1.13 5.903e-300 922.0
PYH3_k127_6584867_1 Glycosyltransferase family 9 (heptosyltransferase) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006641 487.0
PYH3_k127_6584867_2 Dolichyl-phosphate-mannose-protein mannosyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005618 362.0
PYH3_k127_6584867_3 Lysylphosphatidylglycerol synthase TM region K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008887 282.0
PYH3_k127_6587256_0 Histidine kinase - - - 0.0 1210.0
PYH3_k127_6587256_1 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 4.017e-286 888.0
PYH3_k127_6587256_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003638 509.0
PYH3_k127_6587256_3 Motif C-terminal to PAS motifs (likely to contribute to PAS structural domain) K03776 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000209 246.0
PYH3_k127_6587256_4 Response regulator receiver K07814 - - 0.0000000000000000000000000000000000000000000000000000000000005943 211.0
PYH3_k127_6587256_5 Catalyzes the oxidation of L-aspartate to iminoaspartate K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000002355 205.0
PYH3_k127_6587256_6 - - - - 0.000000000000000000000000000000000000001256 150.0
PYH3_k127_6600553_0 Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate K00615 - 2.2.1.1 0.0 1171.0
PYH3_k127_6600553_1 Mediates influx of magnesium ions K03284 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008915 513.0
PYH3_k127_6600553_2 Sodium calcium exchanger membrane K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004143 482.0
PYH3_k127_6600553_3 Belongs to the FPP GGPP synthase family K00795 - 2.5.1.1,2.5.1.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001372 459.0
PYH3_k127_6600553_4 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002884 433.0
PYH3_k127_6600553_5 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003661 422.0
PYH3_k127_6600553_6 Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001772 290.0
PYH3_k127_6600553_7 Ferredoxin - - - 0.00000000000000000000000000000000000000000000000000000000000000000000003326 242.0
PYH3_k127_6600553_8 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.000000000000000000000000000000000000000000000000000000000000000003 226.0
PYH3_k127_6600553_9 Thioredoxin - - - 0.00000000000000000002095 95.0
PYH3_k127_6670348_0 His Kinase A (phosphoacceptor) domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002164 299.0
PYH3_k127_6670348_1 Protein of unknown function (DUF3365) - - - 0.00000000000000000000000000000000000000000000000000000000000000000001688 242.0
PYH3_k127_6670348_2 cheY-homologous receiver domain - - - 0.000000000000000000000000000000000000000009191 157.0
PYH3_k127_6670348_3 amino acid transport K02030,K10001 - - 0.000000000000000000000000000000000003093 146.0
PYH3_k127_6695475_0 Glycosyl transferases group 1 K17249 - 2.4.1.292 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007431 531.0
PYH3_k127_6695475_1 glycosyl transferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001942 445.0
PYH3_k127_6695475_2 polysaccharide deacetylase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009945 388.0
PYH3_k127_6695475_3 serine threonine protein kinase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003854 346.0
PYH3_k127_6695475_4 involved in cell wall biogenesis - - - 0.00006681 45.0
PYH3_k127_6742965_0 HD domain - - - 1.383e-253 789.0
PYH3_k127_6742965_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00821 - 2.6.1.11,2.6.1.17 6.804e-224 697.0
PYH3_k127_6742965_10 Part of the ABC transporter complex PstSACB involved in phosphate import - - - 0.00000000002752 69.0
PYH3_k127_6742965_2 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004599 574.0
PYH3_k127_6742965_3 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006778 512.0
PYH3_k127_6742965_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007569 488.0
PYH3_k127_6742965_5 molybdopterin oxidoreductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004539 402.0
PYH3_k127_6742965_6 Ankyrin repeat - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004753 240.0
PYH3_k127_6742965_7 Fad-dependent pyridine nucleotide-disulfide oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000001247 129.0
PYH3_k127_6742965_9 thiamine biosynthesis protein ThiS K03154 - - 0.00000000000000000000001989 102.0
PYH3_k127_6754083_0 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766,K13497 - 2.4.2.18,4.1.3.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001574 539.0
PYH3_k127_6754083_1 ATPase or kinase K06925 - - 0.00000000000000000000000000000000000000000000000000000000000000004989 224.0
PYH3_k127_6754083_2 S4 domain protein - - - 0.00000000000000000000000000000000004278 135.0
PYH3_k127_6754083_3 ABC transporter, ATP-binding protein K01990,K06861 - - 0.0000000000000000000000006678 104.0
PYH3_k127_67765_0 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03092 - - 1.878e-224 700.0
PYH3_k127_67765_1 domain protein K09944 - - 2.049e-220 692.0
PYH3_k127_67765_2 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007157 591.0
PYH3_k127_67765_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 424.0
PYH3_k127_67765_4 tigr02757 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002896 336.0
PYH3_k127_67765_5 ABC transporter, ATP-binding protein K01990,K06861 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001333 290.0
PYH3_k127_67765_6 mechanosensitive ion channel - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001215 278.0
PYH3_k127_6813276_0 nitrate reductase (NAP). Only expressed at high levels during aerobic growth. NapAB complex receives electrons from the membrane-anchored tetraheme protein NapC K02567 - - 0.0 1774.0
PYH3_k127_6813276_1 phosphorelay sensor kinase activity K01768,K07673,K07713 - 2.7.13.3,4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004104 321.0
PYH3_k127_6813276_2 Electron transfer subunit of the periplasmic nitrate reductase complex NapAB K02568 - - 0.000000000000000000000004276 104.0
PYH3_k127_6895730_0 Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB K02454 - - 3.05e-294 907.0
PYH3_k127_6909853_0 flagellar biosynthesis K02404 - - 1.404e-241 751.0
PYH3_k127_6909853_1 flagellar motor switch protein K02416 - - 3.074e-195 612.0
PYH3_k127_6909853_2 Belongs to the ParA family K04562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004447 495.0
PYH3_k127_6909853_3 flagellar motor switch protein K02417 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004277 411.0
PYH3_k127_6909853_4 Belongs to the sigma-70 factor family K02405 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 379.0
PYH3_k127_6909853_5 Belongs to the LOG family K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001031 344.0
PYH3_k127_6909853_6 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.00000000000000000000000000000000000000000000000000000000000000002812 223.0
PYH3_k127_6909853_7 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase K00950 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000000000000003226 224.0
PYH3_k127_6909853_8 - - - - 0.0000000000000000000000000000000000000000003157 159.0
PYH3_k127_69742_0 Glycerol-3-phosphate dehydrogenase K11473 - - 1.922e-259 801.0
PYH3_k127_69742_1 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008264 601.0
PYH3_k127_69742_10 Belongs to the 'phage' integrase family K14059 - - 0.00000000000000000000000000000000000000000001414 169.0
PYH3_k127_69742_2 Histidine kinase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001537 533.0
PYH3_k127_69742_3 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003647 497.0
PYH3_k127_69742_4 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003294 434.0
PYH3_k127_69742_5 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001106 417.0
PYH3_k127_69742_6 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009144 383.0
PYH3_k127_69742_7 Belongs to the anaerobic coproporphyrinogen-III oxidase family - GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006778,GO:0006779,GO:0006782,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016491,GO:0016627,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044464,GO:0046148,GO:0046483,GO:0046501,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0051989,GO:0055114,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002121 361.0
PYH3_k127_69742_8 Histidine kinase K03407 - 2.7.13.3 0.0000000000000000000000000000000000000000000000000000000000000000004751 230.0
PYH3_k127_69742_9 Pyridoxamine 5'-phosphate oxidase K07226 - - 0.0000000000000000000000000000000000000000000000000000000006467 205.0
PYH3_k127_7388431_0 SMART GGDEF domain containing protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004281 535.0
PYH3_k127_7388431_1 ABC transporter substrate binding protein - - - 0.00000000000000000000000000000000000000000000000000000001555 223.0
PYH3_k127_7398461_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1192.0
PYH3_k127_7398461_1 RNA binding S1 domain protein K06959 - - 0.0 1129.0
PYH3_k127_7398461_10 HD domain K07814 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007749 388.0
PYH3_k127_7398461_11 abc transporter atp-binding protein K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001808 370.0
PYH3_k127_7398461_12 Outer membrane efflux protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008169 368.0
PYH3_k127_7398461_13 Belongs to the protein N5-glutamine methyltransferase family K02493 - 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003267 310.0
PYH3_k127_7398461_14 Dtw domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001753 305.0
PYH3_k127_7398461_15 Outer membrane protein beta-barrel family K02014 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000388 317.0
PYH3_k127_7398461_16 membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001085 256.0
PYH3_k127_7398461_17 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain K02483 - - 0.00000000000000000000000000000000000000000000000000000000004801 211.0
PYH3_k127_7398461_18 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000000000000000000000000004117 195.0
PYH3_k127_7398461_19 diguanylate cyclase K13590 - 2.7.7.65 0.000000000000000000000000000000000000000000000002663 184.0
PYH3_k127_7398461_2 COG0631 Serine threonine protein phosphatase K12132 - 2.7.11.1 5.749e-266 827.0
PYH3_k127_7398461_20 DnaJ molecular chaperone homology domain - - - 0.000000000000000000000000000000000000000000005075 164.0
PYH3_k127_7398461_21 diguanylate cyclase K21019 - 2.7.7.65 0.0000000000000000000000000000000000000000008503 172.0
PYH3_k127_7398461_22 Histidine kinase K07645 - 2.7.13.3 0.00000000000000000000000000000000000002758 159.0
PYH3_k127_7398461_23 Bacterial transcription activator, effector binding domain - - - 0.00000000000000000000000006463 113.0
PYH3_k127_7398461_24 Outer membrane efflux protein K15725 - - 0.000000000000000002169 98.0
PYH3_k127_7398461_27 - - - - 0.00000000005582 63.0
PYH3_k127_7398461_28 Protein of unknown function (DUF3240) - - - 0.0000000006747 63.0
PYH3_k127_7398461_3 COG2223 Nitrate nitrite transporter K02575 - - 5.722e-242 758.0
PYH3_k127_7398461_4 Two-component sensor histidine kinase response regulator - - - 4.674e-208 677.0
PYH3_k127_7398461_5 Peptidase M48 K06013 - 3.4.24.84 3.167e-207 650.0
PYH3_k127_7398461_6 ABC transporter K02004 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005253 548.0
PYH3_k127_7398461_7 TIGRFAM Diguanylate cyclase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002348 490.0
PYH3_k127_7398461_8 abc transporter atp-binding protein K02065 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001041 451.0
PYH3_k127_7398461_9 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003818 423.0
PYH3_k127_7399798_0 Belongs to the dCTP deaminase family K01494 - 3.5.4.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001653 379.0
PYH3_k127_7399798_1 Asparagine synthase, glutamine-hydrolyzing K01953 - 6.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 363.0
PYH3_k127_7399798_2 GAF domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001973 253.0
PYH3_k127_7399798_3 GAF domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002701 251.0
PYH3_k127_7399798_4 Protein of unknown function (DUF465) K09794 - - 0.000000000000000000000000000000000002363 138.0
PYH3_k127_7417154_0 Belongs to the class-II aminoacyl-tRNA synthetase family K04567 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.6 9.874e-304 935.0
PYH3_k127_7417154_1 phospho-2-dehydro-3-deoxyheptonate aldolase K01626 - 2.5.1.54 7.109e-278 856.0
PYH3_k127_7417154_10 COG2199 FOG GGDEF domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009217 383.0
PYH3_k127_7417154_11 Domain of unknown function (DUF1882) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 334.0
PYH3_k127_7417154_12 Belongs to the Fur family K03711 GO:0003674,GO:0005488,GO:0005515,GO:0042802 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005191 290.0
PYH3_k127_7417154_13 Colicin V production protein K03558 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001083 290.0
PYH3_k127_7417154_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000005773 225.0
PYH3_k127_7417154_15 17 kDa surface antigen - - - 0.00000000000000000000000000000000000000000000000000000000000001782 218.0
PYH3_k127_7417154_16 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.000000000000000000000000000000000000000000000000000001176 198.0
PYH3_k127_7417154_17 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000001858 188.0
PYH3_k127_7417154_18 Belongs to the ArsC family - - - 0.00000000000000000000000000000000000000006405 154.0
PYH3_k127_7417154_19 Sporulation related domain K03749 - - 0.0000000000000000000000000000000000000004181 157.0
PYH3_k127_7417154_2 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.1.2.1 2.208e-255 789.0
PYH3_k127_7417154_20 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.0000000000000000000000000000000000002888 142.0
PYH3_k127_7417154_21 Histidine kinase - - - 0.0000000000000000000000000000000000003804 146.0
PYH3_k127_7417154_3 twitching motility protein K02669 - - 6.887e-205 641.0
PYH3_k127_7417154_4 chemotaxis protein - - - 1.765e-199 631.0
PYH3_k127_7417154_5 Belongs to the GPI family K01810 - 5.3.1.9 2.174e-196 619.0
PYH3_k127_7417154_6 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005402 595.0
PYH3_k127_7417154_7 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001836 474.0
PYH3_k127_7417154_8 Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules K04763 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001832 397.0
PYH3_k127_7417154_9 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 - 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006064 381.0
PYH3_k127_7428299_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1125.0
PYH3_k127_7428299_1 General glycosylation pathway protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001245 524.0
PYH3_k127_7428299_2 Ribosomal protein L11 methyltransferase K02687 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 481.0
PYH3_k127_7428299_3 lipopolysaccharide heptosyltransferase K02841 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001876 476.0
PYH3_k127_7428299_4 1-(5-phosphoribosyl)-5- (5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase K01814 - 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001875 441.0
PYH3_k127_7428299_5 COG0457 FOG TPR repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004088 415.0
PYH3_k127_7428299_6 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001527 361.0
PYH3_k127_7428299_7 phosphatidylserine decarboxylase K01613 - 4.1.1.65 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004103 301.0
PYH3_k127_7428299_8 Chemotaxis protein cheY K03413 - - 0.000000000000000000000000000000000000000000000000000000000000000000000001389 245.0
PYH3_k127_7435293_0 Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.20 0.0 1133.0
PYH3_k127_7435293_1 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily K01889 - 6.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000001414 250.0
PYH3_k127_7435293_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.000000000000000000000006759 104.0
PYH3_k127_7467450_0 TonB dependent receptor K02014 - - 3.739e-312 969.0
PYH3_k127_7467450_1 Glycolate oxidase subunit K00104 - 1.1.3.15 7.947e-280 862.0
PYH3_k127_7467450_2 it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins K02314 GO:0003674,GO:0005488,GO:0005515,GO:0042802 3.6.4.12 3.631e-275 850.0
PYH3_k127_7467450_3 Competence protein K02238 - - 8.052e-211 662.0
PYH3_k127_7467450_4 peptidase M23 - - - 6.381e-200 628.0
PYH3_k127_7467450_5 Belongs to the agmatine deiminase family - - - 5.599e-194 607.0
PYH3_k127_7467450_6 Plasminogen-binding protein pgbA N-terminal - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000293 356.0
PYH3_k127_7467450_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000001021 237.0
PYH3_k127_7467450_8 ribonuclease BN K07058 - - 0.0000000000000000000000000000000000000000000000000000002069 203.0
PYH3_k127_7481779_0 lytic murein transglycosylase K08309 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 464.0
PYH3_k127_7481779_1 molybdopterin-guanine dinucleotide biosynthesis protein K03753 - - 0.0000000000000000000000000000006281 122.0
PYH3_k127_7481779_2 - - - - 0.000002413 56.0
PYH3_k127_7483870_0 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 0.0 1036.0
PYH3_k127_7483870_1 PFAM AMP-dependent synthetase and ligase K01897 - 6.2.1.3 1.011e-268 835.0
PYH3_k127_7483870_2 PFAM Radical SAM domain protein K04069 - 1.97.1.4 1.035e-202 633.0
PYH3_k127_7483870_3 Major Facilitator Superfamily K06902 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 553.0
PYH3_k127_7483870_4 Prolyl oligopeptidase family K06889 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002562 256.0
PYH3_k127_7483870_5 COG2518 Protein-L-isoaspartate carboxylmethyltransferase K00573 - 2.1.1.77 0.00000000000000000000000000000000000000000000000000000000000000136 222.0
PYH3_k127_7483870_6 Protein of unknown function (DUF2459) - - - 0.000000000000000000000000000000000009329 143.0
PYH3_k127_7483870_8 COG1734 DnaK suppressor protein K06204 - - 0.00000000000000000000000000000002154 128.0
PYH3_k127_7495103_0 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.451e-265 824.0
PYH3_k127_7495103_1 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 568.0
PYH3_k127_7495103_2 Belongs to the ClpA ClpB family K03694,K03695 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007306 330.0
PYH3_k127_7495103_3 - - - - 0.00000000000000000000000000000000000000000000000000000000006176 205.0
PYH3_k127_7495103_4 Could be involved in insertion of integral membrane proteins into the membrane - - - 0.00000000000000000000000000000000000000000000000000000008114 196.0
PYH3_k127_7495103_5 Jag_N K06346 - - 0.000000000000000000000000000000000000000000000003071 183.0
PYH3_k127_7495103_6 RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme K03536 - 3.1.26.5 0.0000000000000000000000000000000000000000000001201 170.0
PYH3_k127_7495103_7 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.000000000000000002036 85.0
PYH3_k127_7550876_0 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 - 6.3.5.6,6.3.5.7 2.426e-271 839.0
PYH3_k127_7550876_1 potassium channel protein K10716 - - 3.418e-203 644.0
PYH3_k127_7550876_2 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001304 413.0
PYH3_k127_7550876_3 Glycerol-3-phosphate dehydrogenase K00057 - 1.1.1.94 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001612 320.0
PYH3_k127_7550876_4 TrkA-N domain K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001868 265.0
PYH3_k127_7550876_5 Thiamine monophosphate synthase K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000000000000000002796 244.0
PYH3_k127_7550876_6 Belongs to the ribF family K11753 - 2.7.1.26,2.7.7.2 0.00000000000000000000000000000000000000000000000000000000000001009 217.0
PYH3_k127_7570764_0 Belongs to the TrpC family K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002573 486.0
PYH3_k127_7570764_1 chaperone-mediated protein folding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009659 490.0
PYH3_k127_7570764_2 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007354 389.0
PYH3_k127_7570764_3 methyltransferase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001507 357.0
PYH3_k127_7570764_4 Uncharacterised protein family (UPF0153) K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000001725 233.0
PYH3_k127_7570764_5 GatB Yqey family protein K09117 - - 0.0000000000000000000000000000000000000000000000000000000000000007507 221.0
PYH3_k127_7631792_0 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 - 4.1.1.37 1.671e-218 679.0
PYH3_k127_7631792_1 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 2.264e-205 640.0
PYH3_k127_7631792_2 Radical SAM - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 471.0
PYH3_k127_7631792_3 Uncharacterized protein family, UPF0114 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002232 269.0
PYH3_k127_7631792_4 COG2204 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains K02481 - - 0.00000000000000000000000000000000000000000001072 164.0
PYH3_k127_7658952_0 abc transporter atp-binding protein K06147,K06148 - - 4.703e-296 916.0
PYH3_k127_7658952_1 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K13378 - 1.6.5.3 1.126e-224 709.0
PYH3_k127_7658952_2 Oxidoreductase K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000131 566.0
PYH3_k127_7658952_3 acid membrane antigen A - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009744 490.0
PYH3_k127_7658952_4 NADH-quinone oxidoreductase K00336 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003696 423.0
PYH3_k127_7658952_5 Alkyl hydroperoxide reductase K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003308 387.0
PYH3_k127_7658952_6 acid membrane antigen A - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008254 339.0
PYH3_k127_7658952_7 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000901 260.0
PYH3_k127_7658952_8 NADH-quinone oxidoreductase K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000001768 193.0
PYH3_k127_7658952_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00330 - 1.6.5.3 0.0000000000000000000000000000000000001187 145.0
PYH3_k127_7685964_0 Glutamate synthase K00265 - 1.4.1.13,1.4.1.14 0.0 1630.0
PYH3_k127_7685964_1 Glutamate synthase K00266 - 1.4.1.13,1.4.1.14 1.69e-278 858.0
PYH3_k127_7685964_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007404 362.0
PYH3_k127_7685964_3 Inositol monophosphatase K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007012 322.0
PYH3_k127_7718757_0 ribosomal protein S1 K02945 - - 5e-324 996.0
PYH3_k127_7718757_1 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001077 471.0
PYH3_k127_7718757_2 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 - 2.5.1.19 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004122 357.0
PYH3_k127_7718757_3 - - - - 0.000000000000000000000000000000000000000002122 160.0
PYH3_k127_7718757_4 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 0.000000000000000000000000000000000000000002387 156.0
PYH3_k127_7794234_0 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002445 324.0
PYH3_k127_7794234_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005642 290.0
PYH3_k127_7794234_2 Periplasmic binding protein domain K11959 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001699 255.0
PYH3_k127_7794234_3 Predicted periplasmic lipoprotein (DUF2279) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001299 248.0
PYH3_k127_7794234_4 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.000000000000000000000000000000000000000000000000000007031 191.0
PYH3_k127_7797654_0 growth of symbiont in host cell K07003 - - 3.338e-261 822.0
PYH3_k127_7797654_1 UTP-glucose-1-phosphate uridylyltransferase K00963 - 2.7.7.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000296 496.0
PYH3_k127_7797654_2 PFAM EAL domain - - - 0.00000000000000000000000000000000000000000000000000000000001847 217.0
PYH3_k127_7797654_3 phosphorelay signal transduction system - - - 0.0000000000000000000000000000000000000000000017 172.0
PYH3_k127_7797654_4 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.0000000000000000000000000000000000000000001485 164.0
PYH3_k127_7797654_5 COG0642 Signal transduction histidine kinase - - - 0.0000000000000000000000000000000000000000001612 181.0
PYH3_k127_7797654_6 - - - - 0.00000000000000000002873 95.0
PYH3_k127_7808335_0 Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin K03737 - 1.2.7.1 1.221e-241 751.0
PYH3_k127_7808335_1 Catalyzes the conversion of dihydroorotate to orotate K00226 - 1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 531.0
PYH3_k127_7808335_2 Histidine kinase K03413,K13040 - 2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000005894 274.0
PYH3_k127_7808335_3 Histidine kinase - - - 0.000000000000000000002502 98.0
PYH3_k127_7821900_0 2-nitropropane dioxygenase K00459 - 1.13.12.16 5.849e-210 654.0
PYH3_k127_7821900_1 N-acetylmuramoyl-L-alanine amidase K01448 - 3.5.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006215 429.0
PYH3_k127_7968541_0 phosphorelay sensor kinase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000284 584.0
PYH3_k127_7968541_1 Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin K02401 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007246 550.0
PYH3_k127_7968541_2 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 426.0
PYH3_k127_7968541_3 Belongs to the NadC ModD family K00767 - 2.4.2.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001198 365.0
PYH3_k127_7968541_4 COGs COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000005509 179.0
PYH3_k127_7994161_0 COG1008 NADH ubiquinone oxidoreductase subunit 4 (chain M) K00342 - 1.6.5.3 2.689e-290 896.0
PYH3_k127_7994161_1 Paralysed flagella protein - - - 2.955e-277 873.0
PYH3_k127_7994161_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
PYH3_k127_7994161_2 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 3.1e-276 856.0
PYH3_k127_7994161_3 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.257e-227 722.0
PYH3_k127_7994161_4 COG1009 NADH ubiquinone oxidoreductase subunit 5 (chain L) Multisubunit Na H antiporter MnhA subunit K00341 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001562 519.0
PYH3_k127_7994161_5 4-hydroxybenzoate K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 442.0
PYH3_k127_7994161_6 COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components K02051 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003793 320.0
PYH3_k127_7994161_7 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 - 2.5.1.75 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001079 288.0
PYH3_k127_7994161_8 DUF218 domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001785 250.0
PYH3_k127_7994161_9 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000001744 233.0
PYH3_k127_8044211_0 Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3- (1- carboxyvinyl)oxy benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate K18285 - 2.5.1.120 8.274e-219 680.0
PYH3_k127_8044211_1 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004773 246.0
PYH3_k127_8044211_2 Anthranilate synthase K01658 - 4.1.3.27 0.00000000000000000000000000000009383 124.0
PYH3_k127_8108171_0 Type I secretion system ATPase K12541 - - 0.0 1151.0
PYH3_k127_8108171_1 Outer membrane efflux protein K12543 - - 1.836e-236 739.0
PYH3_k127_8108171_2 HlyD membrane-fusion protein of T1SS K12542 - - 3.549e-229 715.0
PYH3_k127_8108171_3 helix_turn_helix, Lux Regulon - - - 0.00000000000000000000000000000000000000000000000000000000000000000000107 241.0
PYH3_k127_8108171_4 Belongs to the ompA family K03286 - - 0.0000000000000000000000000000000000000000000000000848 183.0
PYH3_k127_8108171_5 von Willebrand factor (vWF) type A domain - - - 0.0000000000000000000000000000000000000002038 170.0
PYH3_k127_818611_0 TonB-dependent receptor - - - 2.287e-258 814.0
PYH3_k127_818611_1 Belongs to the DEAD box helicase family - - - 2.291e-211 663.0
PYH3_k127_818611_10 phosphohistidine phosphatase, SixA K08296 - - 0.0000000000000000000000000000000000000000000000000000000003916 206.0
PYH3_k127_818611_11 - - - - 0.000000000000000000000000000004316 121.0
PYH3_k127_818611_12 endonuclease containing a URI domain K07461 - - 0.000000000000000000000001518 105.0
PYH3_k127_818611_13 His Kinase A (phosphoacceptor) domain - - - 0.0000663 50.0
PYH3_k127_818611_14 pathogenesis - - - 0.0001491 49.0
PYH3_k127_818611_2 EAL domain - - - 3.759e-197 621.0
PYH3_k127_818611_3 aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001809 426.0
PYH3_k127_818611_4 diguanylate cyclase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002215 378.0
PYH3_k127_818611_5 DNA RNA non-specific endonuclease K01173 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001789 360.0
PYH3_k127_818611_6 modulator of drug activity K03923 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001924 332.0
PYH3_k127_818611_7 Protein of unknown function (DUF3108) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001835 298.0
PYH3_k127_818611_8 Formylmethanofuran dehydrogenase, subunit e - - - 0.000000000000000000000000000000000000000000000000000000000000000003968 231.0
PYH3_k127_818611_9 Belongs to the UPF0260 family K09160 - - 0.0000000000000000000000000000000000000000000000000000000000005453 213.0
PYH3_k127_8261051_0 cation transport ATPase K01533,K17686 - 3.6.3.4,3.6.3.54 0.0 1082.0
PYH3_k127_8261051_1 Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose K03272 - 2.7.1.167,2.7.7.70 9.989e-253 785.0
PYH3_k127_8261051_2 ADP-L-glycero-D-manno-heptose-6-epimerase K03274 - 5.1.3.20 3.377e-199 622.0
PYH3_k127_8261051_3 heptosyltransferase ii K02843 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001467 575.0
PYH3_k127_8261051_4 lipopolysaccharide core region biosynthetic process - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 327.0
PYH3_k127_8261051_5 Cytochrome c553 K08738 - - 0.000000000000000000000000000000000000000001202 158.0
PYH3_k127_8261051_6 Cytochrome oxidase maturation protein - - - 0.000000000000000000000000002904 111.0
PYH3_k127_8363928_0 Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family K14393 - - 9.095e-318 977.0
PYH3_k127_8363928_1 signal-transduction protein containing cAMP-binding and CBS domains K07182 - - 1.039e-317 982.0
PYH3_k127_8363928_2 outer membrane porin, OprD family - - - 2.933e-209 657.0
PYH3_k127_8363928_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009699 526.0
PYH3_k127_8363928_4 Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) K09765 - 1.17.99.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 517.0
PYH3_k127_8363928_5 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000122 394.0
PYH3_k127_8363928_6 dna polymerase iii K02342 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005999 360.0
PYH3_k127_8363928_7 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 361.0
PYH3_k127_8363928_8 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 343.0
PYH3_k127_8363928_9 membrane - - - 0.0000000000000000000000000000000000000000000004327 168.0
PYH3_k127_8377940_0 Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site K03723 - - 0.0 1174.0
PYH3_k127_8377940_1 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K00557,K03212,K03215 - 2.1.1.189,2.1.1.190,2.1.1.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001679 537.0
PYH3_k127_8377940_2 Histidine kinase K02484 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009565 497.0
PYH3_k127_8377940_3 metallophosphoesterase K09769 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003038 396.0
PYH3_k127_8377940_4 Metal-dependent hydrolase K07043 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003761 261.0
PYH3_k127_8377940_5 response regulator - - - 0.00000000000000000000000000000000000000000000000000000000000000006689 229.0
PYH3_k127_854694_0 signal transduction protein containing a membrane domain an EAL and a GGDEF domain - - - 1.728e-240 772.0
PYH3_k127_8646042_0 Domain of unknown function (DUF3458_C) ARM repeats K01256 - 3.4.11.2 0.0 1278.0
PYH3_k127_8646042_1 COGs COG1252 NADH dehydrogenase FAD-containing subunit K17218 - 1.8.5.4 5.749e-302 928.0
PYH3_k127_8646042_2 PFAM EAL domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000445 528.0
PYH3_k127_8646042_3 Hpt sensor hybrid histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007665 446.0
PYH3_k127_8646042_4 leucine binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 372.0
PYH3_k127_8646042_5 Uracil-DNA glycosylase K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002772 327.0
PYH3_k127_8646042_6 Transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000000000481 219.0
PYH3_k127_8696781_0 Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction K00962 - 2.7.7.8 4.15e-232 720.0
PYH3_k127_8696781_1 Rhodanese Homology Domain K01011 - 2.8.1.1,2.8.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000806 263.0
PYH3_k127_8696781_2 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.0000000000000000000000000000000000000000000000000000002424 196.0
PYH3_k127_8697558_0 Phosphoesterase family K01114 - 3.1.4.3 2.687e-219 687.0
PYH3_k127_8697558_1 membrane K15270 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001949 421.0
PYH3_k127_8697558_10 of the cytoplasmic domain of flagellar protein FhlB K04061 - - 0.0000000000000000000000000000000000022 138.0
PYH3_k127_8697558_11 Bacterial transcriptional repressor C-terminal - - - 0.0000000000000000000000000000000382 133.0
PYH3_k127_8697558_12 Rubredoxin - - - 0.000000000000000000004359 94.0
PYH3_k127_8697558_2 Belongs to the peptidase S1C family K04771 - 3.4.21.107 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001399 426.0
PYH3_k127_8697558_3 auxin efflux carrier K07088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001347 408.0
PYH3_k127_8697558_4 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002327 374.0
PYH3_k127_8697558_5 COG1881 Phospholipid-binding protein K06910 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008467 318.0
PYH3_k127_8697558_6 Belongs to the pirin family K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000004532 285.0
PYH3_k127_8697558_7 anaphase-promoting complex binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004807 296.0
PYH3_k127_8697558_8 metal-dependent phosphohydrolase, HD sub domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000001122 245.0
PYH3_k127_8697558_9 Bacterial periplasmic substrate-binding proteins - - - 0.000000000000000000000000000000000000000000000000000005197 201.0
PYH3_k127_8762529_0 Belongs to the aconitase IPM isomerase family K01682 GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003730,GO:0003824,GO:0003994,GO:0005488,GO:0006082,GO:0006091,GO:0006099,GO:0006101,GO:0006629,GO:0006631,GO:0008150,GO:0008152,GO:0009056,GO:0009060,GO:0009062,GO:0009987,GO:0015980,GO:0016042,GO:0016054,GO:0016829,GO:0016835,GO:0016836,GO:0016999,GO:0017001,GO:0017144,GO:0019541,GO:0019543,GO:0019626,GO:0019629,GO:0019752,GO:0032787,GO:0042737,GO:0043436,GO:0044237,GO:0044238,GO:0044242,GO:0044248,GO:0044255,GO:0044281,GO:0044282,GO:0045333,GO:0046395,GO:0046459,GO:0047456,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:0072329,GO:0072350,GO:0097159,GO:1901363,GO:1901575 4.2.1.3,4.2.1.99 0.0 1616.0
PYH3_k127_8762529_1 Belongs to the FtsK SpoIIIE SftA family K03466 - - 5.695e-273 858.0
PYH3_k127_8762529_2 Belongs to the DEAD box helicase family K05591 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000008586 213.0
PYH3_k127_878_0 - - - - 1.208e-195 616.0
PYH3_k127_878_1 ABC transporter permease - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001086 536.0
PYH3_k127_878_3 COG1136 ABC-type antimicrobial peptide transport system ATPase component K02003,K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001564 314.0
PYH3_k127_878_4 signal transduction response regulator (GGDEF - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000007191 266.0
PYH3_k127_878_6 - - - - 0.000000000000000000000000000000000000000000000000000000001317 206.0
PYH3_k127_878_7 D-alanyl-D-alanine carboxypeptidase - - - 0.0000000000000000000001665 99.0
PYH3_k127_8782016_0 Sulfatase - - - 0.0 1013.0
PYH3_k127_8782016_1 Sulfatase K03760 - 2.7.8.43 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006755 548.0
PYH3_k127_8782016_2 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000000000000000000002256 233.0
PYH3_k127_8782016_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000000000000000000005581 181.0
PYH3_k127_8888843_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.861e-217 676.0
PYH3_k127_8888843_1 Catalyzes the dehydration of chorismate into 3- (1- carboxyvinyl)oxy benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2) K11782 - 4.2.1.151 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009723 324.0
PYH3_k127_890595_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 2.976e-259 803.0
PYH3_k127_890595_1 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 1.311e-219 686.0
PYH3_k127_890595_2 ABC transporter K11085 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001705 535.0
PYH3_k127_89229_0 phosphate acetyltransferase K00625,K13788 - 2.3.1.8 0.0 1060.0
PYH3_k127_89229_1 Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction K00925 - 2.7.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000539 511.0
PYH3_k127_89229_2 mechanosensitive ion channel K03442 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000972 430.0
PYH3_k127_89229_3 Archaea bacterial proteins of unknown function K06921 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000474 364.0
PYH3_k127_89229_4 Belongs to the phosphoglycerate kinase family K00927 - 2.7.2.3 0.0000000000000000000000000000000000000000000000000000000000000184 216.0
PYH3_k127_89229_5 Phospholipase_D-nuclease N-terminal - - - 0.0000000000000000000000000000000000009529 141.0
PYH3_k127_8993372_0 Histidine kinase K02030 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009208 383.0
PYH3_k127_8993372_1 Histidine kinase K13040 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000004535 238.0
PYH3_k127_9163335_0 Belongs to the aspartokinase family K00928 - 2.7.2.4 8.914e-234 726.0
PYH3_k127_9163335_1 DNA replication regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006193 282.0
PYH3_k127_9163335_2 Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage K08311 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001875 272.0
PYH3_k127_9163335_3 Involved in the biosynthesis of porphyrin-containing compound - - - 0.000000000000009247 73.0
PYH3_k127_9244052_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 1.696e-256 792.0
PYH3_k127_9244052_1 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360 - 5.557e-203 634.0
PYH3_k127_9244052_2 Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides K11065 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000285 327.0
PYH3_k127_9244052_3 AMIN domain - - - 0.00000000000000000000000000000000000000000000000000000001566 203.0
PYH3_k127_9244052_4 - - - - 0.00000000000000000000002507 102.0
PYH3_k127_93210_0 Flagellar Assembly Protein A - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000508 592.0
PYH3_k127_93210_1 Helix-turn-helix domain - - - 0.00000000000000000000000000001179 122.0
PYH3_k127_9374380_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046,K13797 - 2.7.7.6 0.0 2821.0
PYH3_k127_9374380_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2072.0
PYH3_k127_9374380_10 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000209 243.0
PYH3_k127_9374380_11 Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body K02387 - - 0.00000000000000000000000000000000000000000000000000000000000005682 216.0
PYH3_k127_9374380_12 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000004349 209.0
PYH3_k127_9374380_13 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.00000000000000000000000000000000000000000000000000006196 187.0
PYH3_k127_9374380_15 Flagellar hook-basal body complex protein FliE K02408 - - 0.00000000000000000000000000000000000000000006687 161.0
PYH3_k127_9374380_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1356.0
PYH3_k127_9374380_3 Cell division protein FtsI penicillin-binding protein K03587 - 3.4.16.4 0.0 1015.0
PYH3_k127_9374380_4 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 6.437e-213 670.0
PYH3_k127_9374380_5 Belongs to the SEDS family K03588 - - 1.373e-200 632.0
PYH3_k127_9374380_6 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 - 6.3.2.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002945 423.0
PYH3_k127_9374380_7 May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate K21420 - 2.3.2.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002396 419.0
PYH3_k127_9374380_8 Belongs to the flagella basal body rod proteins family K02388 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001249 296.0
PYH3_k127_9374380_9 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000005014 291.0
PYH3_k127_96901_0 YcaO cyclodehydratase, ATP-ad Mg2+-binding K09136 - - 3.424e-277 859.0
PYH3_k127_96901_1 COG0842 ABC-type multidrug transport system, permease component K01992 - - 2.476e-200 629.0
PYH3_k127_96901_2 COG1131 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002786 533.0
PYH3_k127_96901_3 Mate efflux family protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005494 431.0
PYH3_k127_96901_4 HlyD family secretion protein K01993 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005224 413.0
PYH3_k127_96901_5 PFAM Polysaccharide deacetylase K14659,K22278 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 3.5.1.104 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003328 374.0
PYH3_k127_96901_6 helicase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001588 353.0
PYH3_k127_96901_7 - - - - 0.000000000000000000001947 95.0
PYH3_k127_96901_8 Ribosomal RNA adenine dimethylase - - - 0.0000000000000699 71.0