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Overview

ID MAG03231
Name PYH3_bin.39
Sample SMP0075
Taxonomy
Kingdom Bacteria
Phylum Nitrospirota
Class Nitrospiria
Order Nitrospirales
Family Nitrospiraceae
Genus 2-02-FULL-62-14
Species
Assembly information
Completeness (%) 85.32
Contamination (%) 0.26
GC content (%) 63.0
N50 (bp) 21,174
Genome size (bp) 2,131,972

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1864

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_1005717_0 Uncharacterized protein conserved in bacteria (DUF2309) K09822 - - 0.0 1529.0
PYH3_k127_1005717_1 NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006153 404.0
PYH3_k127_1005717_2 LysR substrate binding domain K03717 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001125 348.0
PYH3_k127_1005717_3 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 299.0
PYH3_k127_1005717_4 serine-type endopeptidase activity K08372 - - 0.00000000000000000000000000000000000000000000000000000000001293 221.0
PYH3_k127_1005717_5 Evidence 2b Function of strongly homologous gene - - - 0.00000000000000000000000000000000000000000000000000000001811 200.0
PYH3_k127_1005717_6 NADH-quinone oxidoreductase K00341,K05577 - 1.6.5.3 0.000000000000000000000000000000000000000000000000001235 185.0
PYH3_k127_1005717_7 - - - - 0.0000000000000000000000000000000000001531 147.0
PYH3_k127_1049846_0 ResB-like family K07399 - - 5.897e-227 711.0
PYH3_k127_1049846_1 Cytochrome C assembly protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 550.0
PYH3_k127_1049846_10 Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme K00789 - 2.5.1.6 0.0000000000000000000000000000000000001872 143.0
PYH3_k127_1049846_11 Transcriptional regulatory protein, C terminal K07658 - - 0.00000000004478 63.0
PYH3_k127_1049846_2 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002244 505.0
PYH3_k127_1049846_3 His Kinase A (phosphoacceptor) domain K07636 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003353 496.0
PYH3_k127_1049846_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008795 405.0
PYH3_k127_1049846_5 Cytochrome C biogenesis protein transmembrane region K06196 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003924 377.0
PYH3_k127_1049846_6 Protein of unknown function DUF47 K02039,K07220 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 319.0
PYH3_k127_1049846_7 Thioredoxin-like - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000009602 276.0
PYH3_k127_1049846_8 Tetratricopeptide repeat K05807 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000002989 280.0
PYH3_k127_1049846_9 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000009512 208.0
PYH3_k127_106840_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 1.005e-269 840.0
PYH3_k127_106840_1 Pfam Fatty acid - - - 6.084e-252 813.0
PYH3_k127_106840_10 Dodecin K09165 - - 0.00000000000000000000016 99.0
PYH3_k127_106840_11 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.000000000000000000000518 101.0
PYH3_k127_106840_12 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000008271 99.0
PYH3_k127_106840_13 bacterial OsmY and nodulation domain K04065 GO:0005575,GO:0005623,GO:0006457,GO:0006950,GO:0006970,GO:0006972,GO:0008150,GO:0009628,GO:0009987,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0044464,GO:0050896,GO:0061077 - 0.00000000000000003218 90.0
PYH3_k127_106840_14 Belongs to the UPF0337 (CsbD) family - - - 0.0000000000000051 78.0
PYH3_k127_106840_15 - - - - 0.000000000002538 68.0
PYH3_k127_106840_16 - - - - 0.00000000002797 71.0
PYH3_k127_106840_19 Protein of unknown function (DUF1328) - - - 0.00001405 48.0
PYH3_k127_106840_2 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 3.215e-222 702.0
PYH3_k127_106840_3 alcohol dehydrogenase K13979 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008374 487.0
PYH3_k127_106840_4 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003172 286.0
PYH3_k127_106840_5 Belongs to the SOS response-associated peptidase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003755 273.0
PYH3_k127_106840_6 WYL domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000001696 241.0
PYH3_k127_106840_7 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000009079 222.0
PYH3_k127_106840_8 - - - - 0.00000000000000000000000000000000008188 135.0
PYH3_k127_106840_9 SWI complex, BAF60b domains - - - 0.00000000000000000000000000000001313 128.0
PYH3_k127_1076640_0 Rubrerythrin K22405 - 1.6.3.4 0.0 1216.0
PYH3_k127_1076640_1 Elongator protein 3, MiaB family, Radical SAM - - - 9.192e-292 900.0
PYH3_k127_1076640_10 Transglutaminase-like superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004362 403.0
PYH3_k127_1076640_11 NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus K00057 - 1.1.1.94 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000519 396.0
PYH3_k127_1076640_12 (AIR) carboxylase K06898 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001892 342.0
PYH3_k127_1076640_13 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006054 337.0
PYH3_k127_1076640_14 tRNA 3'-trailer cleavage - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003474 334.0
PYH3_k127_1076640_15 Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 - 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005061 295.0
PYH3_k127_1076640_16 Outer membrane lipoprotein carrier protein LolA K03634 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
PYH3_k127_1076640_17 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002816 272.0
PYH3_k127_1076640_18 Methyladenine glycosylase K01246 - 3.2.2.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000003025 266.0
PYH3_k127_1076640_19 Dimerisation domain of Zinc Transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005232 273.0
PYH3_k127_1076640_2 Iron-sulfur cluster-binding domain - - - 1.084e-273 844.0
PYH3_k127_1076640_20 Nitroreductase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000002362 259.0
PYH3_k127_1076640_21 Winged helix-turn-helix DNA-binding - - - 0.00000000000000000000000000000000000000000000000000000000000000005036 225.0
PYH3_k127_1076640_22 deoxyhypusine monooxygenase activity K02632 - 4.4.1.31 0.000000000000000000000000000000000000000000000000000000000000005026 223.0
PYH3_k127_1076640_27 phosphorelay signal transduction system - - - 0.0000000000000000000002039 103.0
PYH3_k127_1076640_28 3-demethylubiquinone-9 3-O-methyltransferase activity K06219 - - 0.00000000000000000003651 101.0
PYH3_k127_1076640_3 PFAM cell divisionFtsK SpoIIIE K03466 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007101 554.0
PYH3_k127_1076640_4 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 492.0
PYH3_k127_1076640_5 pseudouridine synthase activity K06176 GO:0001522,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001005 469.0
PYH3_k127_1076640_6 Pyridoxal phosphate biosynthetic protein PdxA K00097,K22024 - 1.1.1.262,1.1.1.408,1.1.1.409 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 459.0
PYH3_k127_1076640_7 Sodium/calcium exchanger protein K07301 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001769 447.0
PYH3_k127_1076640_8 Involved in the biosynthesis of a nickel-pincer cofactor ((SCS)Ni(II) pincer complex). Binds Ni(2 ), and functions in nickel delivery to pyridinium-3,5-bisthiocarboxylic acid mononucleotide (P2TMN), to form the mature cofactor. Is thus probably required for the activation of nickel-pincer cofactor- dependent enzymes K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008877 448.0
PYH3_k127_1076640_9 Transport permease protein K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001199 413.0
PYH3_k127_1200880_0 Belongs to the precorrin methyltransferase family K13542 - 2.1.1.107,4.2.1.75 4.24e-221 696.0
PYH3_k127_1200880_1 Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA) K02492 - 1.2.1.70 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000017 613.0
PYH3_k127_1200880_10 Riboflavin kinase K11753 - 2.7.1.26,2.7.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002463 376.0
PYH3_k127_1200880_11 Belongs to the universal ribosomal protein uS2 family K02967 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001087 369.0
PYH3_k127_1200880_12 Cytochrome C assembly protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002087 362.0
PYH3_k127_1200880_13 HNH nucleases - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 352.0
PYH3_k127_1200880_15 Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome K02357 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005411 303.0
PYH3_k127_1200880_16 Mo-molybdopterin cofactor metabolic process K03638 - 2.7.7.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000005631 258.0
PYH3_k127_1200880_17 precorrin-2 dehydrogenase activity K02302,K02304 GO:0003674,GO:0003824,GO:0004851,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0006950,GO:0006970,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008757,GO:0009058,GO:0009628,GO:0009987,GO:0016740,GO:0016741,GO:0018130,GO:0019354,GO:0019438,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046156,GO:0046483,GO:0050896,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.76,2.1.1.107,4.99.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000004059 257.0
PYH3_k127_1200880_18 PFAM AIG2 family protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000009323 253.0
PYH3_k127_1200880_19 Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another K02838 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001263 255.0
PYH3_k127_1200880_2 Delta-aminolevulinic acid dehydratase K01698 - 4.2.1.24 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002977 524.0
PYH3_k127_1200880_20 Bifunctional nuclease K08999 - - 0.0000000000000000000000000000000000000000000000000000000000000000000002886 241.0
PYH3_k127_1200880_21 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000007723 209.0
PYH3_k127_1200880_22 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.0000000000000000000000000000000000000000000000000000000004343 213.0
PYH3_k127_1200880_23 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000000000000006704 202.0
PYH3_k127_1200880_24 cytochrome complex assembly K02200,K04018,K19225,K20543,K21007 - 3.4.21.105 0.000000000000000000000000000000000000000000000000000000006149 201.0
PYH3_k127_1200880_25 Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA K07056 GO:0000154,GO:0000451,GO:0000453,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008171,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016020,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044464,GO:0046483,GO:0070677,GO:0071704,GO:0071840,GO:0071944,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.198 0.0000000000000000000000000000000000000000000000000000001579 202.0
PYH3_k127_1200880_26 Nudix N-terminal - - - 0.00000000000000000000000000000000000000000000000000001877 196.0
PYH3_k127_1200880_27 Belongs to the universal ribosomal protein uS9 family K02996 - - 0.00000000000000000000000000000000000000000000000000005047 190.0
PYH3_k127_1200880_28 Thiamine-binding protein - - - 0.00000000000000000000000000000000000000000000003123 172.0
PYH3_k127_1200880_29 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.00000000000000000000000000000000000000000000487 173.0
PYH3_k127_1200880_3 Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde K00145 - 1.2.1.38 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008708 514.0
PYH3_k127_1200880_30 Bifunctional nuclease K03617,K08999 GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0016020,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000004532 167.0
PYH3_k127_1200880_31 Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes - - - 0.00000000000000000000000000000000000001806 147.0
PYH3_k127_1200880_32 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000002762 139.0
PYH3_k127_1200880_34 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000001437 126.0
PYH3_k127_1200880_35 Sulfurtransferase TusA - - - 0.0000000000000000000000000001564 117.0
PYH3_k127_1200880_36 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.000000000000001143 81.0
PYH3_k127_1200880_4 Zinc-binding dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007408 475.0
PYH3_k127_1200880_5 Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate K00620 - 2.3.1.1,2.3.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004404 475.0
PYH3_k127_1200880_6 Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps K01749 - 2.5.1.61 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004482 448.0
PYH3_k127_1200880_7 Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids K01775 - 5.1.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001351 424.0
PYH3_k127_1200880_8 isomerase activity K06998 - 5.3.3.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 414.0
PYH3_k127_1200880_9 Catalyzes the reversible phosphorylation of UMP to UDP K09903 - 2.7.4.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 384.0
PYH3_k127_1245489_0 Predicted membrane protein (DUF2127) - - - 0.000000000000000000000000000000000000000000007454 169.0
PYH3_k127_1245489_1 Periplasmic lysozyme inhibitor of I-type lysozyme - - - 0.000000000000000000000000000000001394 136.0
PYH3_k127_1245489_2 Acetyltransferase (GNAT) domain - - - 0.00000000000000000000001509 105.0
PYH3_k127_1262311_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0 1326.0
PYH3_k127_1262311_1 Tfp pilus assembly protein tip-associated adhesin K02674 - - 5.246e-300 970.0
PYH3_k127_1262311_11 Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA K07447 - - 0.0000000000000000000000000000000000000000000006867 174.0
PYH3_k127_1262311_13 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.000000000000000000000000000000000000000000483 164.0
PYH3_k127_1262311_15 type IV pilus modification protein PilV K02671,K02681,K10927 - - 0.00000000000000000000000000000001463 132.0
PYH3_k127_1262311_17 protein transport across the cell outer membrane - - - 0.00000000000000000000007045 105.0
PYH3_k127_1262311_18 ATPase activity K02017,K02018,K03750,K15497 - 2.10.1.1,3.6.3.29,3.6.3.55 0.00000000000000000003129 92.0
PYH3_k127_1262311_19 regulation of DNA repair K03565,K19002 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0006974,GO:0007154,GO:0008150,GO:0009432,GO:0009605,GO:0009987,GO:0009991,GO:0019899,GO:0031668,GO:0033554,GO:0043086,GO:0044092,GO:0050790,GO:0050896,GO:0051716,GO:0065007,GO:0065009,GO:0071496 2.4.1.337 0.0000000000000000003036 94.0
PYH3_k127_1262311_2 - - - - 5.527e-271 841.0
PYH3_k127_1262311_21 Uncharacterized small protein (DUF2292) - - - 0.00000000003577 64.0
PYH3_k127_1262311_3 Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage K03553 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001795 582.0
PYH3_k127_1262311_4 peroxidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001088 434.0
PYH3_k127_1262311_5 Competence-damaged protein K03742,K03743 - 3.5.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008528 443.0
PYH3_k127_1262311_6 tungstate binding K02020 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001195 382.0
PYH3_k127_1262311_9 pilus assembly protein PilW K02672 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001031 277.0
PYH3_k127_1298799_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 0.0 1339.0
PYH3_k127_1298799_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0 1326.0
PYH3_k127_1298799_10 Transporter - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 528.0
PYH3_k127_1298799_11 Domain of unknown function (DUF4139) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009237 519.0
PYH3_k127_1298799_12 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003526 441.0
PYH3_k127_1298799_13 Pirin K06911 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001685 411.0
PYH3_k127_1298799_14 Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate K01918 GO:0003674,GO:0003824,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006573,GO:0006575,GO:0006732,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016874,GO:0016879,GO:0016881,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605 6.3.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001579 377.0
PYH3_k127_1298799_15 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006863 355.0
PYH3_k127_1298799_16 ParB-like nuclease domain K03497 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001 356.0
PYH3_k127_1298799_17 methyltransferase K00570 - 2.1.1.17,2.1.1.71 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001722 329.0
PYH3_k127_1298799_18 Inositol monophosphatase family K01092 - 3.1.3.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001044 310.0
PYH3_k127_1298799_19 phosphogluconate dehydrogenase (decarboxylating) activity K00020,K00042 - 1.1.1.31,1.1.1.60 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005733 309.0
PYH3_k127_1298799_2 ABC transporter K06020 - 3.6.3.25 2e-315 970.0
PYH3_k127_1298799_20 Alpha/beta hydrolase family K06999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000073 304.0
PYH3_k127_1298799_21 catechol 2,3-dioxygenase activity K07104 - 1.13.11.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001118 267.0
PYH3_k127_1298799_22 PFAM RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002632 273.0
PYH3_k127_1298799_23 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000005509 257.0
PYH3_k127_1298799_24 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK) K00950 - 2.7.6.3 0.000000000000000000000000000000000000000000000000000000000000000000000000002385 256.0
PYH3_k127_1298799_26 Evidence 4 Homologs of previously reported genes of K15977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000007388 244.0
PYH3_k127_1298799_27 the 2 termini fold to resemble tRNA(Ala) and it encodes a tag peptide , a short internal open reading frame. During trans-translation Ala- aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA K03664 - - 0.00000000000000000000000000000000000000000000000000000000000000000000008106 242.0
PYH3_k127_1298799_28 phosphatase homologous to the C-terminal domain of histone macroH2A1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001011 231.0
PYH3_k127_1298799_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 1.659e-264 818.0
PYH3_k127_1298799_30 pterin-4-alpha-carbinolamine dehydratase K01724 GO:0003674,GO:0003824,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008124,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009987,GO:0016829,GO:0016835,GO:0016836,GO:0017144,GO:0018130,GO:0019438,GO:0019751,GO:0034311,GO:0034312,GO:0034641,GO:0042558,GO:0042559,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 4.2.1.96 0.00000000000000000000000000000000000000000000000000000000001274 209.0
PYH3_k127_1298799_31 MEKHLA domain - - - 0.0000000000000000000000000000000000000000000000000000000003143 205.0
PYH3_k127_1298799_32 peroxiredoxin activity K00627,K01607 - 2.3.1.12,4.1.1.44 0.000000000000000000000000000000000000000000000000000001649 199.0
PYH3_k127_1298799_33 MMPL family K07003 - - 0.000000000000000000000000000000000000000000000000000006634 216.0
PYH3_k127_1298799_34 Protein conserved in bacteria K16785 - - 0.0000000000000000000000000000000000000000000000000002141 188.0
PYH3_k127_1298799_36 Glycerophosphoryl diester phosphodiesterase family K01126 - 3.1.4.46 0.0000000000000000000000000000000000000000000001679 175.0
PYH3_k127_1298799_38 - - - - 0.000000000000000000000000000000000000000000003347 181.0
PYH3_k127_1298799_39 Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE - - - 0.00000000000000000000000000000000000000001472 154.0
PYH3_k127_1298799_4 thymidylate synthase (FAD) activity K03465 - 2.1.1.148 2.675e-252 786.0
PYH3_k127_1298799_40 Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives - - - 0.0000000000000000000000000000000000129 141.0
PYH3_k127_1298799_44 Polymer-forming cytoskeletal - - - 0.00000000000000000000000001507 115.0
PYH3_k127_1298799_45 Protein involved in outer membrane biogenesis - - - 0.00000000000000000000000008019 116.0
PYH3_k127_1298799_46 Protein of unknown function (DUF1653) - - - 0.0000000000000000000000001235 108.0
PYH3_k127_1298799_47 - - - - 0.0000000000000000000000005575 112.0
PYH3_k127_1298799_5 Aminotransferase class I and II K10206 - 2.6.1.83 6.018e-220 685.0
PYH3_k127_1298799_52 Polymer-forming cytoskeletal - - - 0.00000000000004407 78.0
PYH3_k127_1298799_53 Ribosomal protein L7/L12 C-terminal domain - - - 0.000000001363 64.0
PYH3_k127_1298799_55 - - - - 0.000174 53.0
PYH3_k127_1298799_6 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 GO:0003674,GO:0003676,GO:0003677,GO:0003688,GO:0003690,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005886,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006270,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016020,GO:0034641,GO:0034645,GO:0043170,GO:0043565,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071944,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901576,GO:1990837 - 1.84e-212 667.0
PYH3_k127_1298799_7 of the RND superfamily K07003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000559 587.0
PYH3_k127_1298799_8 Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria K02338 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008192 568.0
PYH3_k127_1298799_9 Histidyl-tRNA synthetase K01892 - 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006804 534.0
PYH3_k127_1330486_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 8.321e-259 809.0
PYH3_k127_1330486_1 Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00748 - 2.4.1.182 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 424.0
PYH3_k127_1330486_2 Oxidoreductase family, NAD-binding Rossmann fold - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000153 269.0
PYH3_k127_1330486_3 Domain of unknown function (DUF374) K09778 - - 0.0000000000000000000000000000000000000000000000000000000000000002484 229.0
PYH3_k127_1386011_0 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 342.0
PYH3_k127_1386011_1 - - - - 0.0000000000000000000000000000000000000000000008123 169.0
PYH3_k127_1386011_2 Protein conserved in bacteria - - - 0.00000000000000000000009755 104.0
PYH3_k127_1386011_3 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000001312 88.0
PYH3_k127_1408495_0 DNA topoisomerase II activity K03167 - 5.99.1.3 4.322e-310 962.0
PYH3_k127_1408495_1 hydrogen-translocating pyrophosphatase activity K15987 - 3.6.1.1 1.088e-224 700.0
PYH3_k127_1408495_2 DNA topoisomerase VI subunit A K03166 - 5.99.1.3 5.01e-220 685.0
PYH3_k127_1410190_0 Hsp70 protein K04043,K04044 - - 2.465e-308 953.0
PYH3_k127_1410190_1 Transglycosylase K05366 - 2.4.1.129,3.4.16.4 2.281e-202 658.0
PYH3_k127_1410190_2 DnaJ molecular chaperone homology domain K04082 - - 0.0000000000000000000000000000000000000000000000000000000000000001196 229.0
PYH3_k127_1410190_3 Iron-sulphur cluster assembly - - - 0.00000000000000000000000000000000009748 133.0
PYH3_k127_1418751_0 Belongs to the DegT DnrJ EryC1 family K13010 - 2.6.1.102 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003397 463.0
PYH3_k127_1418751_1 PFAM Glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003534 338.0
PYH3_k127_1418751_2 Methyltransferase domain - - - 0.000000000000000000000000000000000000000000000000000000000004145 222.0
PYH3_k127_1418751_3 Glycosyl transferase 4-like domain - - - 0.0000000000000000000000000000000000000000000000000000000001597 216.0
PYH3_k127_1418751_4 glycosyl transferase - - - 0.000000000000000000000000000000000000000000000000000005868 209.0
PYH3_k127_1418751_5 methyltransferase K16648 - - 0.000000000000000000000000000000000002874 147.0
PYH3_k127_1418751_7 Methionine biosynthesis protein MetW - - - 0.0000000000000000000000002858 118.0
PYH3_k127_1418751_8 Glycosyl transferase, family 2 K00721,K01912,K08301 - 2.4.1.83,6.2.1.30 0.000000000000000002893 96.0
PYH3_k127_1418751_9 Methionine biosynthesis protein MetW - - - 0.000000000000001944 87.0
PYH3_k127_1475070_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 7.529e-258 798.0
PYH3_k127_1475070_1 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 2.917e-223 696.0
PYH3_k127_1475070_10 Methylenetetrahydrofolate reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002054 473.0
PYH3_k127_1475070_11 Acyl transferase domain K00645 - 2.3.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003204 443.0
PYH3_k127_1475070_12 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006521 437.0
PYH3_k127_1475070_13 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003903 415.0
PYH3_k127_1475070_14 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001457 399.0
PYH3_k127_1475070_15 Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate K00606 - 2.1.2.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007283 406.0
PYH3_k127_1475070_16 6-phosphogluconolactonase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009256 347.0
PYH3_k127_1475070_17 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005178 333.0
PYH3_k127_1475070_18 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004217 283.0
PYH3_k127_1475070_19 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000008893 251.0
PYH3_k127_1475070_2 Putative modulator of DNA gyrase K03568 - - 8.864e-207 655.0
PYH3_k127_1475070_20 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.00000000000000000000000000000000000000000000000000000000000000000000204 245.0
PYH3_k127_1475070_21 Mitochondrial small ribosomal subunit Rsm22 - - - 0.000000000000000000000000000000000000000000000000000000000000000005506 236.0
PYH3_k127_1475070_22 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000000000001458 232.0
PYH3_k127_1475070_23 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000003045 220.0
PYH3_k127_1475070_24 Single-strand binding protein family K03111 - - 0.000000000000000000000000000000000000000000000000000000000000002671 220.0
PYH3_k127_1475070_25 Membrane K08984 - - 0.00000000000000000000000000000000000000000000000000000000000004346 220.0
PYH3_k127_1475070_26 Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) K09457 - 1.7.1.13 0.0000000000000000000000000000000000000000000000000000000001685 228.0
PYH3_k127_1475070_28 Uncharacterized ACR, COG1399 K07040 - - 0.000000000000000000000000000000000009367 145.0
PYH3_k127_1475070_29 Binds together with S18 to 16S ribosomal RNA K02990 - - 0.0000000000000000000000000000000001197 136.0
PYH3_k127_1475070_3 PFAM Type II IV secretion system protein K02669 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 572.0
PYH3_k127_1475070_31 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078 - - 0.000000000000000000000001322 115.0
PYH3_k127_1475070_32 Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit K02963 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000008823 96.0
PYH3_k127_1475070_33 zinc-ribbon domain - - - 0.0000000000000000001033 95.0
PYH3_k127_1475070_34 Belongs to the bacterial ribosomal protein bL32 family K02911 GO:0000027,GO:0000302,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006950,GO:0006979,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042221,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0050896,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1990904 - 0.00000000000000007607 81.0
PYH3_k127_1475070_35 Domain of unknown function (DUF4864) - - - 0.000000000005232 70.0
PYH3_k127_1475070_4 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005015 567.0
PYH3_k127_1475070_5 metallopeptidase activity K03592 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002093 558.0
PYH3_k127_1475070_6 Type IV secretion-system coupling protein DNA-binding domain K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002061 529.0
PYH3_k127_1475070_7 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids K00648 - 2.3.1.180 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001394 508.0
PYH3_k127_1475070_8 Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA K03621 - 2.3.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000145 482.0
PYH3_k127_1475070_9 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 GO:0003674,GO:0003824,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006730,GO:0008150,GO:0008152,GO:0009987,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0019238,GO:0044237,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0055114 1.5.1.5,3.5.4.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001432 476.0
PYH3_k127_1481052_0 N-acetylphosphatidylethanolamine-hydrolysing phospholipas activity - - - 1.673e-257 803.0
PYH3_k127_1481052_1 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003499 421.0
PYH3_k127_1481052_2 Male sterility protein K08679 - 5.1.3.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005804 381.0
PYH3_k127_1481052_3 uroporphyrinogen-III synthase activity K01719,K13542 - 2.1.1.107,4.2.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000032 323.0
PYH3_k127_1481052_4 lactoylglutathione lyase activity - - - 0.0000000000000000000000000000000000000000000000000008618 187.0
PYH3_k127_1481052_5 23S rRNA-intervening sequence protein - - - 0.0000000000000003735 81.0
PYH3_k127_1503393_0 Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins K03798 - - 0.0 1075.0
PYH3_k127_1503393_1 Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate K03431 - 5.4.2.10 5.449e-218 684.0
PYH3_k127_1503393_2 Competence protein K02238 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002288 610.0
PYH3_k127_1503393_3 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000808 314.0
PYH3_k127_1503393_4 Phosphoribosyl transferase domain K00760 - 2.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005961 290.0
PYH3_k127_1503393_5 Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine K04075 - 6.3.4.19 0.00000000000000000000000000000000000000000000000000000000000000000000000009575 261.0
PYH3_k127_150584_0 C-terminal, D2-small domain, of ClpB protein K03696 - - 0.0 1431.0
PYH3_k127_150584_1 xylulokinase activity K00854 - 2.7.1.17 9.348e-314 972.0
PYH3_k127_150584_10 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000671 447.0
PYH3_k127_150584_11 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction K01409 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008363 422.0
PYH3_k127_150584_12 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 389.0
PYH3_k127_150584_13 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000031 351.0
PYH3_k127_150584_14 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006178 322.0
PYH3_k127_150584_15 Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase K02356 GO:0003674,GO:0003676,GO:0003723,GO:0003746,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006412,GO:0006414,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000193 312.0
PYH3_k127_150584_16 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000004202 292.0
PYH3_k127_150584_17 Domain of unknown function (DUF1732) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009036 296.0
PYH3_k127_150584_18 Essential for recycling GMP and indirectly, cGMP K00942 - 2.7.4.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000003772 266.0
PYH3_k127_150584_19 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000001118 257.0
PYH3_k127_150584_2 Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate K01679 - 4.2.1.2 1.416e-246 768.0
PYH3_k127_150584_20 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.000000000000000000000000000000000000000000000000000000000000000003704 228.0
PYH3_k127_150584_21 Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring K01935 GO:0003674,GO:0003824,GO:0004141,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016882,GO:0017144,GO:0018130,GO:0019752,GO:0032787,GO:0034641,GO:0042364,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.3.3 0.000000000000000000000000000000000000000000000000000000000000002732 226.0
PYH3_k127_150584_22 Catalyzes a trans-dehydration via an enolate intermediate K03786 - 4.2.1.10 0.000000000000000000000000000000000000000000000000000000001824 203.0
PYH3_k127_150584_23 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 GO:0003674,GO:0003824,GO:0004789,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.3 0.000000000000000000000000000000000000000000000000000522 191.0
PYH3_k127_150584_24 first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA K02160 - - 0.000000000000000000000000000000000000000000000001181 181.0
PYH3_k127_150584_26 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.0000000000000000000000000000000000000000003752 161.0
PYH3_k127_150584_28 - - - - 0.00000000000000000000000000000005046 128.0
PYH3_k127_150584_3 'glutamate synthase K00528,K03388 - 1.18.1.2,1.19.1.1,1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 1.656e-234 731.0
PYH3_k127_150584_30 Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits K03060 - 2.7.7.6 0.000000000000000000000000000005057 129.0
PYH3_k127_150584_32 - - - - 0.00008238 49.0
PYH3_k127_150584_4 Belongs to the citrate synthase family K01647,K01659 - 2.3.3.1,2.3.3.5 3.888e-195 614.0
PYH3_k127_150584_5 GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis K03665 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000144 606.0
PYH3_k127_150584_6 Biotin carboxylase K01961 - 6.3.4.14,6.4.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004307 571.0
PYH3_k127_150584_7 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008183 529.0
PYH3_k127_150584_8 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006995 496.0
PYH3_k127_150584_9 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 - 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001074 466.0
PYH3_k127_161497_0 TonB-dependent receptor - - - 1.587e-264 826.0
PYH3_k127_161497_1 response to nickel cation K07722 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.0000000000000000000000000000000000000000000000000000003281 195.0
PYH3_k127_1744229_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 0.0 1943.0
PYH3_k127_1744229_1 PD-(D/E)XK nuclease superfamily - - - 0.0 1047.0
PYH3_k127_1744229_10 Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA) K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004019 518.0
PYH3_k127_1744229_11 Transporter associated domain K03699 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001164 511.0
PYH3_k127_1744229_12 Acetyl-coenzyme A transporter 1 K08218 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001639 506.0
PYH3_k127_1744229_13 HD domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001542 451.0
PYH3_k127_1744229_14 Indole-3-glycerol phosphate synthase K01609 - 4.1.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002958 391.0
PYH3_k127_1744229_15 The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate K01695 - 4.2.1.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009227 378.0
PYH3_k127_1744229_16 Peptidase C26 K01658 - 4.1.3.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004329 337.0
PYH3_k127_1744229_17 Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001959 334.0
PYH3_k127_1744229_18 N-(5'phosphoribosyl)anthranilate (PRA) isomerase K01817 - 5.3.1.24 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006286 305.0
PYH3_k127_1744229_19 Uncharacterized protein family UPF0004 K18707 - 2.8.4.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000009959 289.0
PYH3_k127_1744229_2 DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA K01972 GO:0003674,GO:0003824,GO:0003909,GO:0003911,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006259,GO:0006266,GO:0006281,GO:0006284,GO:0006288,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016874,GO:0016886,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 6.5.1.2 4.383e-309 961.0
PYH3_k127_1744229_20 Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides K03642 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000973 268.0
PYH3_k127_1744229_21 regulation of RNA biosynthetic process K03567 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002072 253.0
PYH3_k127_1744229_22 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 GO:0003674,GO:0003824,GO:0006464,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0018193,GO:0018206,GO:0019538,GO:0031365,GO:0036211,GO:0042586,GO:0043170,GO:0043412,GO:0043686,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 3.5.1.88 0.0000000000000000000000000000000000000000000000000000000000000000009227 231.0
PYH3_k127_1744229_24 Thioredoxin domain - - - 0.000000000000000000000000000000000000000000008673 163.0
PYH3_k127_1744229_25 ACT domain - - - 0.000000000000000000000000000000000000003371 152.0
PYH3_k127_1744229_26 Cupin domain - - - 0.00000000000000000000000000000000000002712 146.0
PYH3_k127_1744229_28 LysM domain - - - 0.0000000000000000000000000000102 125.0
PYH3_k127_1744229_3 exonuclease activity K16899 - 3.6.4.12 5.543e-308 976.0
PYH3_k127_1744229_30 - - - - 0.000000000000000000002057 99.0
PYH3_k127_1744229_4 tRNA synthetases class II (D, K and N) K04567 - 6.1.1.6 3.675e-266 825.0
PYH3_k127_1744229_5 Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia K01657 - 4.1.3.27 3.907e-249 776.0
PYH3_k127_1744229_6 The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine K01696 - 4.2.1.20 4.141e-218 680.0
PYH3_k127_1744229_7 Carbon-nitrogen hydrolase K03820 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005952 588.0
PYH3_k127_1744229_8 MacB-like periplasmic core domain K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002803 573.0
PYH3_k127_1744229_9 Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA K02836 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008822 542.0
PYH3_k127_1787562_0 Aldehyde oxidase and xanthine dehydrogenase, a b hammerhead K11177 - 1.17.1.4 3.285e-266 837.0
PYH3_k127_1787562_1 PFAM 2Fe-2S -binding K03518,K07302,K13483 - 1.2.5.3,1.3.99.16 0.000000000000000000000000000000000000000000000000000000000003027 212.0
PYH3_k127_1882246_0 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.0 1304.0
PYH3_k127_1882246_1 Carbohydrate phosphorylase K00688 - 2.4.1.1 0.0 1094.0
PYH3_k127_1882246_10 - K01992 - - 6.378e-194 617.0
PYH3_k127_1882246_12 Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S K03149 - 2.8.1.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002815 478.0
PYH3_k127_1882246_13 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Interaction with FtsY leads to the transfer of the RNC complex to the Sec translocase for insertion into the membrane, the hydrolysis of GTP by both Ffh and FtsY, and the dissociation of the SRP-FtsY complex into the individual components K03106 - 3.6.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001211 481.0
PYH3_k127_1882246_14 ATPase activity K01990,K09697 - 3.6.3.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002318 469.0
PYH3_k127_1882246_15 Nucleotidyl transferase K00963 - 2.7.7.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000351 438.0
PYH3_k127_1882246_16 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005488,GO:0005515,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005839,GO:0005886,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010498,GO:0016020,GO:0016787,GO:0019538,GO:0019774,GO:0019899,GO:0019941,GO:0030163,GO:0032991,GO:0035375,GO:0040007,GO:0043170,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0051603,GO:0051704,GO:0070003,GO:0070011,GO:0071704,GO:0071944,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003067 388.0
PYH3_k127_1882246_17 Peptidase family M23 K21471 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003278 395.0
PYH3_k127_1882246_18 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 402.0
PYH3_k127_1882246_19 Belongs to the RNA methyltransferase TrmD family K00554 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0016772,GO:0016779,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050518,GO:0070567,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 376.0
PYH3_k127_1882246_2 UvrD-like helicase C-terminal domain K03657 - 3.6.4.12 0.0 1019.0
PYH3_k127_1882246_20 Peptidase family M23 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001045 359.0
PYH3_k127_1882246_21 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001647 348.0
PYH3_k127_1882246_22 Belongs to the ABC-4 integral membrane protein family. FtsX subfamily K09811 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006952 331.0
PYH3_k127_1882246_23 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000405 336.0
PYH3_k127_1882246_24 - K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007629 332.0
PYH3_k127_1882246_25 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K03432 - 3.4.25.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006672 314.0
PYH3_k127_1882246_26 ABC transporter K09812 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006575 308.0
PYH3_k127_1882246_27 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 - 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001127 287.0
PYH3_k127_1882246_3 Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position K00700 - 2.4.1.18 2.518e-320 997.0
PYH3_k127_1882246_30 Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) K00788 - 2.5.1.3 0.00000000000000000000000000000000000000000000000000000000003223 211.0
PYH3_k127_1882246_31 This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site K02884 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000000006277 186.0
PYH3_k127_1882246_32 Uncharacterized protein conserved in bacteria (DUF2062) K09928 - - 0.000000000000000000000000000000000000000000000002651 182.0
PYH3_k127_1882246_33 DNA-directed DNA polymerase activity K02347,K03581,K04477 - 3.1.11.5 0.0000000000000000000000000000000000000000000832 164.0
PYH3_k127_1882246_34 ribosome binding K02860 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0030490,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0040007,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360 - 0.0000000000000000000000000000000000000000003373 164.0
PYH3_k127_1882246_35 peptidoglycan binding K03642 - - 0.000000000000000000000000000000000000000002135 163.0
PYH3_k127_1882246_36 Uncharacterised protein family UPF0102 K07460 - - 0.0000000000000000000000000000000000009205 144.0
PYH3_k127_1882246_38 transcription factor binding - - - 0.000000000000000000000000001161 123.0
PYH3_k127_1882246_39 Belongs to the bacterial ribosomal protein bS16 family K02959 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000001611 113.0
PYH3_k127_1882246_4 protein catabolic process K13527 GO:0000302,GO:0000502,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005886,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0010499,GO:0016020,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019538,GO:0019941,GO:0022623,GO:0022624,GO:0030163,GO:0030312,GO:0032991,GO:0033554,GO:0034599,GO:0034614,GO:0035690,GO:0042221,GO:0042493,GO:0042802,GO:0043170,GO:0043335,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044424,GO:0044464,GO:0044877,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070628,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097366,GO:0140030,GO:0140035,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170,GO:1902494,GO:1905368,GO:1905369 - 1.569e-291 904.0
PYH3_k127_1882246_41 ThiS family K03154 - - 0.00000000000000000000649 94.0
PYH3_k127_1882246_42 - - - - 0.0000000000000001752 85.0
PYH3_k127_1882246_43 - - - - 0.0000000003249 69.0
PYH3_k127_1882246_44 Outer membrane lipoprotein Slp family K07285 - - 0.00000006208 62.0
PYH3_k127_1882246_47 Phosphate starvation-inducible protein, PSIF - - - 0.000001773 55.0
PYH3_k127_1882246_48 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.00007302 46.0
PYH3_k127_1882246_5 Surface antigen K07277 - - 5.188e-284 891.0
PYH3_k127_1882246_6 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 1.618e-272 841.0
PYH3_k127_1882246_7 O-methyltransferase activity K13571,K20814 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0006464,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0016810,GO:0016811,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019941,GO:0030163,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0036211,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0051603,GO:0070490,GO:0070647,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 3.5.1.119,6.3.1.19 2.768e-246 768.0
PYH3_k127_1882246_8 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 - - 3.934e-217 685.0
PYH3_k127_1882246_9 tail specific protease K03797 - 3.4.21.102 6.059e-209 659.0
PYH3_k127_2034638_0 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 6.812e-215 676.0
PYH3_k127_2034638_1 Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines K05541 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006834 479.0
PYH3_k127_2034638_10 efflux transmembrane transporter activity - - - 0.0000000000000000004552 97.0
PYH3_k127_2034638_2 Possible lysine decarboxylase K06966 - 3.2.2.10 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000187 457.0
PYH3_k127_2034638_3 Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR) K01589 - 6.3.4.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002741 444.0
PYH3_k127_2034638_4 Protein of unknown function (DUF692) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001282 447.0
PYH3_k127_2034638_5 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003155 396.0
PYH3_k127_2034638_6 Rhomboid family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001054 338.0
PYH3_k127_2034638_7 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000000000000000000000001968 228.0
PYH3_k127_2034638_8 maF-like protein K03215,K06287 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0005575,GO:0005618,GO:0005623,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0030145,GO:0030312,GO:0036218,GO:0036221,GO:0042802,GO:0043167,GO:0043169,GO:0044464,GO:0046872,GO:0046914,GO:0047429,GO:0071944 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000765 226.0
PYH3_k127_2051336_0 PhoQ Sensor - - - 2.394e-202 643.0
PYH3_k127_2055619_0 5TM C-terminal transporter carbon starvation CstA K06200 - - 0.0 1015.0
PYH3_k127_2055619_1 Penicillin-binding Protein dimerisation domain K03587 - 3.4.16.4 5.777e-255 798.0
PYH3_k127_2055619_10 Cell wall formation K01921 - 6.3.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008434 424.0
PYH3_k127_2055619_11 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00992 - 2.7.7.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003196 421.0
PYH3_k127_2055619_12 Cell wall formation K00075 - 1.3.1.98 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008418 406.0
PYH3_k127_2055619_13 Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) K02563 - 2.4.1.227 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000125 401.0
PYH3_k127_2055619_14 lysyltransferase activity K07027 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004926 377.0
PYH3_k127_2055619_15 Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA K03438 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016434,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0070475,GO:0071424,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.199 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001649 374.0
PYH3_k127_2055619_16 Nucleotidyl transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 338.0
PYH3_k127_2055619_17 Belongs to the TPP enzyme family K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001793 316.0
PYH3_k127_2055619_18 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K09459 - 4.1.1.82 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001945 276.0
PYH3_k127_2055619_19 Protein of unknown function (DUF520) K09767 - - 0.000000000000000000000000000000000000000000000000000000000000001711 221.0
PYH3_k127_2055619_2 Belongs to the MurCDEF family K01924 - 6.3.2.8 5.057e-238 741.0
PYH3_k127_2055619_22 Lipoprotein - - - 0.00000000000000000000000000000004962 138.0
PYH3_k127_2055619_23 Evidence 5 No homology to any previously reported sequences - - - 0.0000000000000000000000005611 107.0
PYH3_k127_2055619_24 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.000002199 53.0
PYH3_k127_2055619_3 acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan K01928 - 6.3.2.13 3.076e-204 649.0
PYH3_k127_2055619_4 Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein K01929 - 6.3.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006435 583.0
PYH3_k127_2055619_5 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan K01000 - 2.7.8.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 557.0
PYH3_k127_2055619_6 Evidence 2b Function of strongly homologous gene K01740,K03430,K05306,K09469 GO:0003674,GO:0003824 2.5.1.49,2.6.1.37,3.11.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 535.0
PYH3_k127_2055619_7 Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) K01925 - 6.3.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000371 535.0
PYH3_k127_2055619_8 Cell cycle protein K03588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 511.0
PYH3_k127_2055619_9 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003829 475.0
PYH3_k127_2059135_0 aldehyde ferredoxin oxidoreductase K03738 - 1.2.7.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004722 576.0
PYH3_k127_2059135_1 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005538 350.0
PYH3_k127_2059135_2 Zinc-binding dehydrogenase - - - 0.00000000000000000000000000000000000001452 145.0
PYH3_k127_2059135_3 Alcohol dehydrogenase GroES-like domain K00098 - 1.1.1.264 0.00000000000000000000001203 104.0
PYH3_k127_2077195_0 TonB-dependent receptor - - - 3.569e-258 802.0
PYH3_k127_2077195_1 His Kinase A (phosphoacceptor) domain K02482 - 2.7.13.3 2.874e-207 662.0
PYH3_k127_2077195_2 Belongs to the DNA glycosylase MPG family K03652 GO:0003674,GO:0003824,GO:0003905,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0140097,GO:1901360 3.2.2.21 0.00000000000000000000000000000000000000000000000000000000000000000000001985 247.0
PYH3_k127_2077195_4 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.000000004353 59.0
PYH3_k127_2224518_0 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006968 358.0
PYH3_k127_2224518_1 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001079 342.0
PYH3_k127_2224518_2 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002492 293.0
PYH3_k127_2224518_3 Glycoprotease family K14742 - - 0.00000000000000000000000000000000000000000000000000000000000000007302 230.0
PYH3_k127_2224518_5 Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane) - - - 0.000000000000000000000000000000000000000000000000000000006733 208.0
PYH3_k127_2224518_6 Acetyltransferase (GNAT) domain K03789 - 2.3.1.128 0.0000000000000000000000000000000000002878 149.0
PYH3_k127_2224518_7 Outer membrane efflux protein - - - 0.000000000000000000000002748 103.0
PYH3_k127_2224518_8 Protein of unknown function (DUF465) K09794 - - 0.00000000000000005312 83.0
PYH3_k127_2271532_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1445.0
PYH3_k127_2271532_1 In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance K00951 - 2.7.6.5 0.0 1143.0
PYH3_k127_2271532_10 thiosulfate sulfurtransferase activity K01011,K21028 - 2.8.1.1,2.8.1.11,2.8.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007333 447.0
PYH3_k127_2271532_11 Carbon-nitrogen hydrolase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004443 427.0
PYH3_k127_2271532_12 heat shock protein binding K03686,K05516 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001048 277.0
PYH3_k127_2271532_13 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002788 268.0
PYH3_k127_2271532_14 NADPH-dependent FMN reductase K03809 - 1.6.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005378 271.0
PYH3_k127_2271532_15 imidazolonepropionase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000001825 237.0
PYH3_k127_2271532_17 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000008007 172.0
PYH3_k127_2271532_18 - - - - 0.000000000000000000000000000000000000000004212 156.0
PYH3_k127_2271532_19 HemY protein K02498 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 0.000000000000000000000000000000000000000196 152.0
PYH3_k127_2271532_2 hydrogen-translocating pyrophosphatase activity K15987 - 3.6.1.1 0.0 1044.0
PYH3_k127_2271532_24 Small metal-binding protein - - - 0.000000000000000008936 87.0
PYH3_k127_2271532_3 metalloendopeptidase activity K08602 - - 7.249e-264 824.0
PYH3_k127_2271532_4 denitrification pathway - - - 7.105e-232 722.0
PYH3_k127_2271532_5 efflux transmembrane transporter activity K12340 - - 1.248e-224 706.0
PYH3_k127_2271532_6 AMP-binding enzyme C-terminal domain K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001868 589.0
PYH3_k127_2271532_7 tRNA 3'-trailer cleavage K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006463 527.0
PYH3_k127_2271532_8 Histone deacetylase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003407 509.0
PYH3_k127_2271532_9 aminopeptidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002813 490.0
PYH3_k127_2342054_0 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004571 550.0
PYH3_k127_2342054_1 Protein involved in response to NO K07234 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006923 518.0
PYH3_k127_2342054_2 PFAM Metal-dependent phosphohydrolase, HD K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004941 434.0
PYH3_k127_2342054_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006378 306.0
PYH3_k127_2342054_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000009775 256.0
PYH3_k127_2342054_5 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000001696 172.0
PYH3_k127_2342054_6 resolution of meiotic recombination intermediates K05516 - - 0.000000000000000000000000000000000002062 141.0
PYH3_k127_2447001_0 Cation transporter/ATPase, N-terminus - - - 0.0 1292.0
PYH3_k127_2447001_1 adenylylsulfate kinase activity K00860,K00955 - 2.7.1.25,2.7.7.4 0.00000000000000000000000000000000000000000000000000000000002861 210.0
PYH3_k127_2447001_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000000000006818 106.0
PYH3_k127_2447001_3 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.00000000001096 68.0
PYH3_k127_2464287_0 siderophore transport K02014 - - 0.0 1082.0
PYH3_k127_2464287_1 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 - 6.1.1.10 2.966e-292 909.0
PYH3_k127_2464287_10 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000000000000000000000000000000000000000000000000000000001773 222.0
PYH3_k127_2464287_11 Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine K01579 - 4.1.1.11 0.00000000000000000000000000000000000000000000000000000000000003404 216.0
PYH3_k127_2464287_13 Bacterial protein of unknown function (DUF948) - - - 0.0000000000000000000000000000000212 131.0
PYH3_k127_2464287_14 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02435 - 6.3.5.6,6.3.5.7 0.000000000000000000002032 110.0
PYH3_k127_2464287_15 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000002899 87.0
PYH3_k127_2464287_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) K02433 - 6.3.5.6,6.3.5.7 4.3e-254 790.0
PYH3_k127_2464287_3 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 GO:0003674,GO:0003824,GO:0004360,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006002,GO:0006040,GO:0006047,GO:0006139,GO:0006464,GO:0006486,GO:0006487,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008483,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009225,GO:0009987,GO:0016740,GO:0016769,GO:0019538,GO:0019637,GO:0034641,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0055086,GO:0070085,GO:0070548,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.6.1.16 2.093e-225 713.0
PYH3_k127_2464287_4 Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain K04042 - 2.3.1.157,2.7.7.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009113 586.0
PYH3_k127_2464287_5 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003303 432.0
PYH3_k127_2464287_6 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02341 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004885 391.0
PYH3_k127_2464287_7 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007724 353.0
PYH3_k127_2464287_8 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 295.0
PYH3_k127_2464287_9 Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis K00943 - 2.7.4.9 0.0000000000000000000000000000000000000000000000000000000000000001101 229.0
PYH3_k127_2535880_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 431.0
PYH3_k127_2535880_1 Mitochondrial biogenesis AIM24 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004012 377.0
PYH3_k127_2535880_2 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000004848 303.0
PYH3_k127_2535880_3 Lipoprotein - - - 0.000000000000000000000000000003301 130.0
PYH3_k127_2535880_4 cell adhesion involved in biofilm formation - - - 0.0000000000000000000000004274 112.0
PYH3_k127_2571124_0 Phage integrase, N-terminal SAM-like domain K03733 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000178 350.0
PYH3_k127_2571124_1 Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery K01419 - 3.4.25.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000005628 287.0
PYH3_k127_2571124_2 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 0.0000000000000000000000000000000000000000000000000000000000000000006712 232.0
PYH3_k127_2571124_3 this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis K03667 - - 0.0000000000000000000000000000000000000000000000000000000000001132 214.0
PYH3_k127_2658485_0 Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane K03070 GO:0000166,GO:0003674,GO:0003824,GO:0005215,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008144,GO:0008150,GO:0008320,GO:0008565,GO:0015031,GO:0015399,GO:0015405,GO:0015440,GO:0015450,GO:0015462,GO:0015833,GO:0016020,GO:0016021,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0022804,GO:0022857,GO:0022884,GO:0030554,GO:0031224,GO:0031226,GO:0031522,GO:0032553,GO:0032555,GO:0032559,GO:0032991,GO:0033036,GO:0033220,GO:0035639,GO:0036094,GO:0042623,GO:0042626,GO:0042886,GO:0042887,GO:0043167,GO:0043168,GO:0043492,GO:0043952,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0055085,GO:0071702,GO:0071705,GO:0071806,GO:0071944,GO:0097159,GO:0097367,GO:1901265,GO:1901363,GO:1904680 - 0.0 1485.0
PYH3_k127_2658485_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K04771 - 3.4.21.107 4.291e-204 646.0
PYH3_k127_2658485_10 response to nickel cation K07722 GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001130,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0006355,GO:0008150,GO:0009889,GO:0009890,GO:0009892,GO:0009987,GO:0010468,GO:0010556,GO:0010558,GO:0010605,GO:0010629,GO:0016043,GO:0016151,GO:0019219,GO:0019222,GO:0022607,GO:0031323,GO:0031324,GO:0031326,GO:0031327,GO:0031333,GO:0032991,GO:0032993,GO:0042802,GO:0043167,GO:0043169,GO:0043254,GO:0043565,GO:0043933,GO:0044085,GO:0044087,GO:0044212,GO:0045892,GO:0045934,GO:0046872,GO:0046914,GO:0048519,GO:0048523,GO:0050789,GO:0050794,GO:0051128,GO:0051129,GO:0051171,GO:0051172,GO:0051252,GO:0051253,GO:0051259,GO:0051260,GO:0051262,GO:0051289,GO:0060255,GO:0065003,GO:0065007,GO:0071840,GO:0080090,GO:0097159,GO:0140110,GO:1901363,GO:1902679,GO:1903506,GO:1903507,GO:1990837,GO:2000112,GO:2000113,GO:2000142,GO:2000143,GO:2001141 - 0.00000000000000003022 81.0
PYH3_k127_2658485_11 Putative S-adenosyl-L-methionine-dependent methyltransferase - - - 0.000000000000004226 78.0
PYH3_k127_2658485_2 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001377 354.0
PYH3_k127_2658485_3 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001694 324.0
PYH3_k127_2658485_4 Peptidyl-prolyl cis-trans isomerase K01802,K03772,K03773 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007687 298.0
PYH3_k127_2658485_5 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process K03673 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005623,GO:0006457,GO:0008150,GO:0008152,GO:0009987,GO:0015035,GO:0015036,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0030288,GO:0030313,GO:0031975,GO:0042221,GO:0042597,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0055114,GO:0070887,GO:0071236,GO:0140096 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 262.0
PYH3_k127_2658485_6 cell redox homeostasis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006508 241.0
PYH3_k127_2658485_7 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000000000000001012 211.0
PYH3_k127_2658485_8 - - - - 0.00000000000000000000000000000000000000000000000000000001168 207.0
PYH3_k127_2658485_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07285 - - 0.0000000000000000000000000000000000000001103 156.0
PYH3_k127_2680668_0 Acts as a magnesium transporter K06213 - - 4.846e-206 649.0
PYH3_k127_2680668_1 Synthesizes alpha-1,4-glucan chains using ADP-glucose K00703 GO:0003674,GO:0003824,GO:0016740,GO:0016757 2.4.1.21 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 589.0
PYH3_k127_2680668_2 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004273 410.0
PYH3_k127_2680668_3 Involved in DNA repair and RecF pathway recombination K03584 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000003645 286.0
PYH3_k127_2680668_4 Protein of unknown function (DUF971) - - - 0.0000000000000000000000000000000000000000000000000000000000002738 212.0
PYH3_k127_2733054_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 2643.0
PYH3_k127_2733054_1 PFAM blue (type 1) copper domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008152 529.0
PYH3_k127_2733054_2 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009324 407.0
PYH3_k127_2733054_3 PFAM Formylglycine-generating sulfatase enzyme - - - 0.00000000000000000187 87.0
PYH3_k127_2768001_0 - - - - 0.000000000000000000000000000000000000000000000000000002883 209.0
PYH3_k127_2768001_1 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000002521 140.0
PYH3_k127_2781889_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.0 1176.0
PYH3_k127_2781889_1 von Willebrand factor (vWF) type A domain K02448 - - 0.0 1037.0
PYH3_k127_2781889_10 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003182 603.0
PYH3_k127_2781889_11 stress-induced mitochondrial fusion K04088 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001189 492.0
PYH3_k127_2781889_12 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 495.0
PYH3_k127_2781889_13 Uncharacterised conserved protein (DUF2156) K01163,K06940 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004784 487.0
PYH3_k127_2781889_14 response regulator K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006758 479.0
PYH3_k127_2781889_15 Rieske (2fe-2S) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006455 462.0
PYH3_k127_2781889_16 Associated with various cellular activities K04748 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 456.0
PYH3_k127_2781889_17 Polysaccharide biosynthesis protein K01784 - 5.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002452 457.0
PYH3_k127_2781889_18 aldo-keto reductase (NADP) activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007788 449.0
PYH3_k127_2781889_19 YmdB-like protein K09769 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002489 431.0
PYH3_k127_2781889_2 Formate--tetrahydrofolate ligase K01938 GO:0003674,GO:0003824,GO:0004329,GO:0004477,GO:0004488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006144,GO:0006575,GO:0006725,GO:0006732,GO:0006760,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009112,GO:0009113,GO:0009256,GO:0009257,GO:0009396,GO:0009987,GO:0016053,GO:0016491,GO:0016645,GO:0016646,GO:0016787,GO:0016810,GO:0016814,GO:0016874,GO:0016879,GO:0018130,GO:0019238,GO:0019438,GO:0019752,GO:0034641,GO:0042398,GO:0042440,GO:0042558,GO:0042559,GO:0043436,GO:0043603,GO:0043604,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0046653,GO:0046654,GO:0051186,GO:0051188,GO:0055086,GO:0055114,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.3 2.075e-245 769.0
PYH3_k127_2781889_20 stress-induced mitochondrial fusion K04087 GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006508,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0008233,GO:0009266,GO:0009408,GO:0009628,GO:0009897,GO:0009986,GO:0016020,GO:0016021,GO:0016787,GO:0019538,GO:0031224,GO:0031226,GO:0031233,GO:0032991,GO:0043086,GO:0043170,GO:0044092,GO:0044238,GO:0044425,GO:0044459,GO:0044464,GO:0050790,GO:0050896,GO:0065007,GO:0065009,GO:0071575,GO:0071704,GO:0071944,GO:0098552,GO:0098796,GO:0140096,GO:1901564 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 429.0
PYH3_k127_2781889_21 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001104 424.0
PYH3_k127_2781889_22 Fatty acid desaturase K00507 - 1.14.19.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002249 406.0
PYH3_k127_2781889_23 methyltransferase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 398.0
PYH3_k127_2781889_24 oxidoreductase activity, acting on CH-OH group of donors K00059 - 1.1.1.100 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009182 374.0
PYH3_k127_2781889_25 Peptidase family M23 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006179 319.0
PYH3_k127_2781889_26 FtsJ-like methyltransferase K06442 - 2.1.1.226,2.1.1.227 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005698 302.0
PYH3_k127_2781889_27 transferase activity, transferring glycosyl groups K20742 - 3.4.14.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 296.0
PYH3_k127_2781889_28 of the alpha beta superfamily K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004072 298.0
PYH3_k127_2781889_29 Uncharacterized protein conserved in bacteria (DUF2064) K09931 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001156 285.0
PYH3_k127_2781889_3 Lysine-2,3-aminomutase K01843 - 5.4.3.2 2.287e-212 663.0
PYH3_k127_2781889_30 diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000005202 285.0
PYH3_k127_2781889_31 helix_turn_helix, Lux Regulon - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001399 258.0
PYH3_k127_2781889_32 ferredoxin-thioredoxin reductase activity K17892 GO:0003674,GO:0003824,GO:0005488,GO:0006091,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0015979,GO:0016491,GO:0016730,GO:0022900,GO:0030385,GO:0044237,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114 1.8.7.2 0.000000000000000000000000000000000000000000000000000000000000000000000003046 253.0
PYH3_k127_2781889_33 protein disulfide oxidoreductase activity K07390 GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051536,GO:0051537,GO:0051540 - 0.00000000000000000000000000000000000000000000000000000001626 198.0
PYH3_k127_2781889_34 diguanylate cyclase - - - 0.000000000000000000000000000000000000000000000000000002018 215.0
PYH3_k127_2781889_35 Rhodanese Homology Domain - - - 0.000000000000000000000000000000000000000000000001996 175.0
PYH3_k127_2781889_39 positive regulation of type IV pilus biogenesis K07343 - - 0.000000000000000000000000000000002448 131.0
PYH3_k127_2781889_4 Endoribonuclease that initiates mRNA decay K18682 - - 2.241e-204 640.0
PYH3_k127_2781889_40 PFAM ATP-binding region, ATPase domain protein domain protein - - - 0.00000000000000000000000000000001898 148.0
PYH3_k127_2781889_41 glutathione transferase activity K00799 - 2.5.1.18 0.0000000000000000000000000000435 120.0
PYH3_k127_2781889_42 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.000000000000000000000000004346 115.0
PYH3_k127_2781889_43 exodeoxyribonuclease VII activity K03602 - 3.1.11.6 0.000000000000000000000000005179 123.0
PYH3_k127_2781889_44 Histidine kinase K03406 - - 0.0000000000000000000000009758 121.0
PYH3_k127_2781889_45 Belongs to the BolA IbaG family K05527,K22066 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008360,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0018130,GO:0019438,GO:0019538,GO:0022603,GO:0022604,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050793,GO:0050794,GO:0051128,GO:0051604,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097428,GO:0097659,GO:0106035,GO:1901360,GO:1901362,GO:1901564,GO:1901576 - 0.00000000000000000000001163 103.0
PYH3_k127_2781889_46 DUF167 K09131 - - 0.00000000000000000002421 93.0
PYH3_k127_2781889_47 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000008951 98.0
PYH3_k127_2781889_48 - - - - 0.0000000000000006896 78.0
PYH3_k127_2781889_49 COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain - - - 0.00000000000003016 79.0
PYH3_k127_2781889_5 methyltransferase K07755 - 2.1.1.137 1.371e-199 627.0
PYH3_k127_2781889_6 HI0933 family K07007 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001754 623.0
PYH3_k127_2781889_7 2'-deoxycytidine 5'-triphosphate deaminase (DCD) K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002329 609.0
PYH3_k127_2781889_8 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002203 606.0
PYH3_k127_2781889_9 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003181 603.0
PYH3_k127_2790641_0 GHKL domain K13598 - 2.7.13.3 0.0 1037.0
PYH3_k127_2790641_1 Bacterial regulatory protein, Fis family K13599 - - 1.097e-220 692.0
PYH3_k127_2790641_10 Peptidase family M48 K03799 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004181 406.0
PYH3_k127_2790641_11 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086,K03087 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001368 372.0
PYH3_k127_2790641_12 cobalamin binding K21089,K21972,K22491 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002248 370.0
PYH3_k127_2790641_13 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001401 327.0
PYH3_k127_2790641_14 PFAM Adenylate and Guanylate cyclase catalytic domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001208 346.0
PYH3_k127_2790641_15 MazG nucleotide pyrophosphohydrolase domain K02499 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001669 314.0
PYH3_k127_2790641_16 Belongs to the glutathione peroxidase family K00432,K20207 - 1.11.1.22,1.11.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 293.0
PYH3_k127_2790641_19 Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family K03215 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008169,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016436,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070041,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.190 0.00000000000000000000000000000000000000000000000000000000000004948 230.0
PYH3_k127_2790641_2 Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III K01599 GO:0003674,GO:0003824,GO:0004853,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006778,GO:0006779,GO:0006783,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009987,GO:0016829,GO:0016830,GO:0016831,GO:0018130,GO:0019438,GO:0033013,GO:0033014,GO:0034641,GO:0042168,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.1.37 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004989 579.0
PYH3_k127_2790641_20 TspO/MBR family K05770 - - 0.0000000000000000000000000000000000000000000000000000001432 199.0
PYH3_k127_2790641_21 Yqey-like protein K09117 - - 0.0000000000000000000000000000000000000000000000000008554 188.0
PYH3_k127_2790641_22 - - - - 0.00000000000000000000000000000000000000000000000001338 184.0
PYH3_k127_2790641_23 Sigma factor PP2C-like phosphatases K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000004098 204.0
PYH3_k127_2790641_24 - - - - 0.0000000000000000000000000000000000000000000000002454 177.0
PYH3_k127_2790641_25 Ferredoxin - - - 0.0000000000000000000000000000000000000000000000198 172.0
PYH3_k127_2790641_26 - - - - 0.0000000000000000000000000000000000000000001742 162.0
PYH3_k127_2790641_27 - K14588 - - 0.00000000000000000000000000000000000000003248 156.0
PYH3_k127_2790641_28 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.0000000000000000000000000000000000000001411 159.0
PYH3_k127_2790641_29 Peptidase MA superfamily - - - 0.0000000000000000000000000000000000000001972 164.0
PYH3_k127_2790641_3 Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX K00231 - 1.3.3.15,1.3.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008901 575.0
PYH3_k127_2790641_30 Domain of unknown function (DUF1844) - - - 0.00000000000000000000000000000000000001586 151.0
PYH3_k127_2790641_33 Belongs to the anti-sigma-factor antagonist family - - - 0.00000000000000000000000006106 112.0
PYH3_k127_2790641_34 Belongs to the acylphosphatase family K01512 GO:0003674,GO:0003824,GO:0003998,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0016787,GO:0016817,GO:0016818,GO:0050896 3.6.1.7 0.000000000000000001979 91.0
PYH3_k127_2790641_35 ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner K01338 - 3.4.21.53 0.00000000000007127 82.0
PYH3_k127_2790641_36 - - - - 0.0000001389 61.0
PYH3_k127_2790641_39 - - - - 0.0003166 44.0
PYH3_k127_2790641_4 PhoQ Sensor - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002012 548.0
PYH3_k127_2790641_5 alanine dehydrogenase activity K00259 GO:0000286,GO:0001666,GO:0003674,GO:0003824,GO:0005575,GO:0005576,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006082,GO:0006520,GO:0006522,GO:0006524,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009056,GO:0009063,GO:0009078,GO:0009080,GO:0009628,GO:0009653,GO:0009987,GO:0016020,GO:0016054,GO:0016491,GO:0016638,GO:0019752,GO:0030154,GO:0030312,GO:0030435,GO:0032502,GO:0036293,GO:0043436,GO:0043934,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0048646,GO:0048856,GO:0048869,GO:0050896,GO:0055114,GO:0070482,GO:0071704,GO:0071944,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 1.4.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005909 535.0
PYH3_k127_2790641_6 AIR synthase related protein, N-terminal domain K01933 - 6.3.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000903 514.0
PYH3_k127_2790641_7 Squalene/phytoene synthase K00801 - 2.5.1.21 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004559 461.0
PYH3_k127_2790641_8 transmembrane transport K02532,K05820,K08167,K08218,K08369 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006585 462.0
PYH3_k127_2790641_9 Catalyzes the ferrous insertion into protoporphyrin IX K01772 - 4.99.1.1,4.99.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001843 437.0
PYH3_k127_2830837_0 Phosphoglycerate kinase K00927 - 2.7.2.3 3.901e-216 675.0
PYH3_k127_2830837_1 Tetratricopeptide repeat - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003649 608.0
PYH3_k127_2830837_10 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 GO:0003674,GO:0003824,GO:0004807,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006006,GO:0006066,GO:0006071,GO:0006081,GO:0006082,GO:0006090,GO:0006091,GO:0006094,GO:0006096,GO:0006139,GO:0006163,GO:0006164,GO:0006165,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006754,GO:0006757,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009132,GO:0009135,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009166,GO:0009167,GO:0009168,GO:0009179,GO:0009185,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0016051,GO:0016052,GO:0016053,GO:0016310,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0018130,GO:0019318,GO:0019319,GO:0019359,GO:0019362,GO:0019363,GO:0019400,GO:0019405,GO:0019438,GO:0019439,GO:0019563,GO:0019637,GO:0019682,GO:0019693,GO:0019751,GO:0019752,GO:0032787,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042866,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044262,GO:0044270,GO:0044271,GO:0044275,GO:0044281,GO:0044282,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046031,GO:0046034,GO:0046164,GO:0046166,GO:0046174,GO:0046184,GO:0046364,GO:0046390,GO:0046394,GO:0046434,GO:0046483,GO:0046496,GO:0046700,GO:0046939,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0072521,GO:0072522,GO:0072524,GO:0072525,GO:0090407,GO:1901135,GO:1901137,GO:1901292,GO:1901293,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1901615,GO:1901616 5.3.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000003584 268.0
PYH3_k127_2830837_11 MotA/TolQ/ExbB proton channel family K03562 - - 0.000000000000000000000000000000000000000000000000000000000000000000000917 243.0
PYH3_k127_2830837_12 Protein tyrosine kinase K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000002542 214.0
PYH3_k127_2830837_14 Biopolymer transport protein ExbD/TolR K03560 - - 0.0000000000000000000000000000000000000000000000001413 188.0
PYH3_k127_2830837_15 Peptidase M50 - - - 0.0000000000000000000000000000000000000000000000001503 188.0
PYH3_k127_2830837_16 This protein binds to 23S rRNA in the presence of protein L20 K02888 GO:0003674,GO:0003735,GO:0005198 - 0.000000000000000000000000000000000000001612 149.0
PYH3_k127_2830837_17 Belongs to the bacterial ribosomal protein bL27 family K02899 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000009401 151.0
PYH3_k127_2830837_18 Preprotein translocase SecG subunit K03075 - - 0.000000000000000000000000000000000008365 139.0
PYH3_k127_2830837_19 Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation K09710 - - 0.000000000000000000000000000003428 124.0
PYH3_k127_2830837_2 Periplasmic binding protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003268 609.0
PYH3_k127_2830837_20 - - - - 0.0000001711 58.0
PYH3_k127_2830837_21 PEGA domain - - - 0.0000002322 64.0
PYH3_k127_2830837_3 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00134 - 1.2.1.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000306 565.0
PYH3_k127_2830837_4 tRNA synthetases class I (W and Y) K01867 - 6.1.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003576 558.0
PYH3_k127_2830837_5 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004954 531.0
PYH3_k127_2830837_6 Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate K00931 - 2.7.2.11 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003794 516.0
PYH3_k127_2830837_7 An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control K03979 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001021 417.0
PYH3_k127_2830837_8 integrase domain protein SAM domain protein K03733,K04763 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 298.0
PYH3_k127_2830837_9 Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) K00969 - 2.7.7.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000006536 268.0
PYH3_k127_283921_0 Dehydratase family K01687 - 4.2.1.9 9.229e-319 981.0
PYH3_k127_283921_1 PP-loop family K21947 - 2.8.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003693 475.0
PYH3_k127_283921_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K05516 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 402.0
PYH3_k127_283921_3 nitric oxide dioxygenase activity K00523 - 1.17.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001288 296.0
PYH3_k127_283921_4 MarC family integral membrane protein K05595 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000002194 267.0
PYH3_k127_283921_5 ATP-independent chaperone mediated protein folding - - - 0.0000000000000000000000000000000000002571 147.0
PYH3_k127_283921_6 peptidase - - - 0.00000000000000000000000000000002568 129.0
PYH3_k127_283921_7 thiamine diphosphate biosynthetic process K03154 - - 0.0000000000000000000000319 103.0
PYH3_k127_283921_8 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.00000000002913 63.0
PYH3_k127_285451_0 protoporphyrinogen oxidase activity K01854 - 5.4.99.9 4.545e-198 643.0
PYH3_k127_285451_1 Belongs to the DegT DnrJ EryC1 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008661 544.0
PYH3_k127_285451_2 carbamoyl transferase, NodU family K00612,K16035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001638 489.0
PYH3_k127_285451_3 phospho-N-acetylmuramoyl-pentapeptide-transferase activity K02851 - 2.7.8.33,2.7.8.35 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005462 426.0
PYH3_k127_285451_4 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004493 356.0
PYH3_k127_285451_5 Dehydratase family K01687 - 4.2.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 314.0
PYH3_k127_285451_6 PFAM Glycosyl transferase, group 1 - - - 0.00000000000000000000000000000000000000001285 161.0
PYH3_k127_285451_8 lipolytic protein G-D-S-L family - - - 0.000000000004209 78.0
PYH3_k127_2988356_0 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002637 310.0
PYH3_k127_2988356_1 Pterin binding enzyme K00548,K15023 - 2.1.1.13,2.1.1.258 0.0000000000000000000000000000000000000000000000001074 181.0
PYH3_k127_2988356_2 - - - - 0.00000000000000000000000000000000000000000000003555 171.0
PYH3_k127_3075546_0 ATP-grasp domain K01905,K22224 - 6.2.1.13 1.351e-263 845.0
PYH3_k127_3075546_1 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 9.774e-213 668.0
PYH3_k127_3075546_10 polyphosphate kinase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001254 288.0
PYH3_k127_3075546_11 Phosphoribosyl transferase domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000002409 242.0
PYH3_k127_3075546_12 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.0000000000000000000000000000000000000000000000000000000000000000001201 235.0
PYH3_k127_3075546_13 amine dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000003534 223.0
PYH3_k127_3075546_14 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000000000000000000000000000000000001479 223.0
PYH3_k127_3075546_16 Cytochrome c K00406 - - 0.0000000000000000000000000000000000000000000000001255 183.0
PYH3_k127_3075546_18 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000009971 129.0
PYH3_k127_3075546_2 Sulfate transporter antisigma-factor antagonist STAS K03321 - - 5.825e-202 652.0
PYH3_k127_3075546_20 PFAM blue (type 1) copper domain protein K00368 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.2.1 0.0000000000000000000009851 102.0
PYH3_k127_3075546_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002845 524.0
PYH3_k127_3075546_4 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K07147 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004061 460.0
PYH3_k127_3075546_5 Pyruvate kinase K00873 - 2.7.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007086 417.0
PYH3_k127_3075546_6 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003884 387.0
PYH3_k127_3075546_7 Polyphosphate kinase 2 (PPK2) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002469 299.0
PYH3_k127_3075546_8 Cytochrome c K12263 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002513 288.0
PYH3_k127_3075546_9 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000012 291.0
PYH3_k127_3076527_0 Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) K01662 - 2.2.1.7 0.0 1054.0
PYH3_k127_3076527_1 Squalene-hopene cyclase C-terminal domain K06045 - 4.2.1.129,5.4.99.17 0.0 1049.0
PYH3_k127_3076527_10 MlaD protein K02067 - - 0.0000000000000000000000000000000000000000000000000000000000000007221 222.0
PYH3_k127_3076527_11 adenosylhomocysteine nucleosidase activity K01243,K03527 - 1.17.7.4,3.2.2.9 0.00000000000000000000000000000000000000000000000000000009066 204.0
PYH3_k127_3076527_12 Domain of unknown function (DUF3463) - - - 0.0000000000000000000000006826 104.0
PYH3_k127_3076527_13 oxidoreductase activity - - - 0.00000000000008145 72.0
PYH3_k127_3076527_2 Required for chromosome condensation and partitioning K03529 - - 0.0 1028.0
PYH3_k127_3076527_3 Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate K03526 GO:0003674,GO:0003824,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016491,GO:0016725,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0032787,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046429,GO:0046490,GO:0052592,GO:0055114,GO:0071704,GO:0090407,GO:1901135,GO:1901576 1.17.7.1,1.17.7.3 5.345e-216 674.0
PYH3_k127_3076527_4 Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis K03527 - 1.17.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001948 553.0
PYH3_k127_3076527_5 Surface antigen - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001472 520.0
PYH3_k127_3076527_6 Permease MlaE K02066 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 396.0
PYH3_k127_3076527_7 long-chain fatty acid transporting porin activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005083 370.0
PYH3_k127_3076527_8 ABC transporter K02065 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001139 354.0
PYH3_k127_3076527_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.00000000000000000000000000000000000000000000000000000000000000000001314 239.0
PYH3_k127_3129168_1 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000003383 156.0
PYH3_k127_3129168_2 FecR protein - - - 0.0000000003796 70.0
PYH3_k127_3129168_3 Tetratricopeptide repeat - - - 0.000023 57.0
PYH3_k127_339158_0 Protein of unknown function, DUF255 K06888 - - 0.0 1617.0
PYH3_k127_339158_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524,K07012 - 3.6.1.11,3.6.1.40 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004998 559.0
PYH3_k127_339158_2 Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides K03684 - 3.1.13.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008912 471.0
PYH3_k127_339158_3 heat shock protein binding K05516,K05801,K18481 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0097159,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000001089 251.0
PYH3_k127_339158_4 arsenate reductase (glutaredoxin) activity K00537 - 1.20.4.1 0.000000000000000000000000000000000000000000001425 169.0
PYH3_k127_339158_5 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.000000000000000000000000000001793 128.0
PYH3_k127_3398792_0 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 - 6.1.1.9 0.0 1233.0
PYH3_k127_3398792_1 Heat shock 70 kDa protein K04043 - - 0.0 1100.0
PYH3_k127_3398792_10 transferase activity, transferring hexosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000134 400.0
PYH3_k127_3398792_11 Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation K07082 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001246 383.0
PYH3_k127_3398792_12 Belongs to the sirtuin family. Class K12410 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003063 370.0
PYH3_k127_3398792_13 Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis K03525 - 2.7.1.33 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005583 361.0
PYH3_k127_3398792_14 Photosynthesis system II assembly factor YCF48 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001091 346.0
PYH3_k127_3398792_15 Quinolinate phosphoribosyl transferase, C-terminal domain K00767 - 2.4.2.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004335 341.0
PYH3_k127_3398792_16 phosphatase activity K07025 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006553 313.0
PYH3_k127_3398792_17 protein serine/threonine phosphatase activity K01090,K20074 - 3.1.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002192 273.0
PYH3_k127_3398792_18 protein kinase activity K12132 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000004393 278.0
PYH3_k127_3398792_19 Endoribonuclease L-PSP - - - 0.000000000000000000000000000000000000000000000000000000000000000000001074 240.0
PYH3_k127_3398792_2 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 3.083e-224 702.0
PYH3_k127_3398792_20 Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit K09761 - 2.1.1.193 0.0000000000000000000000000000000000000000000000000000000000000000006213 235.0
PYH3_k127_3398792_21 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.000000000000000000000000000000000000000000000000000000000000003387 235.0
PYH3_k127_3398792_22 Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2) K11991 - 3.5.4.33 0.000000000000000000000000000000000000000000000000000000007969 203.0
PYH3_k127_3398792_23 Biotin/lipoate A/B protein ligase family K03524 - 6.3.4.15 0.000000000000000000000000000000000000000000000000002776 192.0
PYH3_k127_3398792_24 Radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000003535 196.0
PYH3_k127_3398792_25 histone H2A K63-linked ubiquitination - - - 0.000000000000000000000000000000000000000000004569 173.0
PYH3_k127_3398792_26 Radical SAM domain protein - - - 0.00000000000000000000000000000000000000000005087 172.0
PYH3_k127_3398792_27 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.000000000000000000000000000000000000000002921 163.0
PYH3_k127_3398792_28 Psort location Cytoplasmic, score K22227 - - 0.000000000000000000000000000000000000006759 159.0
PYH3_k127_3398792_29 Anti-sigma-K factor rskA K18682 - - 0.00000000000000000000000000000000000006257 154.0
PYH3_k127_3398792_3 guanyl-nucleotide exchange factor activity - - - 4.829e-223 704.0
PYH3_k127_3398792_30 Protein of unknown function (DUF1284) K09706 - - 0.00000000000000000000000001349 115.0
PYH3_k127_3398792_31 Uncharacterised nucleotidyltransferase - - - 0.0000000000000007346 89.0
PYH3_k127_3398792_32 ATPase-coupled phosphate ion transmembrane transporter activity - - - 0.00000005612 64.0
PYH3_k127_3398792_33 methyltransferase - - - 0.000004676 57.0
PYH3_k127_3398792_34 Psort location Cytoplasmic, score - - - 0.00001253 53.0
PYH3_k127_3398792_35 signal peptide processing K13280 - 3.4.21.89 0.0001309 53.0
PYH3_k127_3398792_4 - K02600 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0043244,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:1903506,GO:2000112,GO:2001141 - 3.799e-211 667.0
PYH3_k127_3398792_5 serine threonine protein kinase K12132 - 2.7.11.1 1.989e-205 667.0
PYH3_k127_3398792_6 Phosphotransfer between the C1 and C5 carbon atoms of pentose K01839 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008973,GO:0009056,GO:0009058,GO:0009117,GO:0009166,GO:0009262,GO:0009264,GO:0009987,GO:0016853,GO:0016866,GO:0016868,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0033554,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0055086,GO:0071704,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 5.4.2.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005413 477.0
PYH3_k127_3398792_7 Pfam Adenylate and Guanylate cyclase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003402 434.0
PYH3_k127_3398792_8 DnaJ central domain K03686 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002491 411.0
PYH3_k127_3427336_0 Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane K03980 - - 4.893e-251 784.0
PYH3_k127_3427336_1 Uncharacterized ACR, YdiU/UPF0061 family K08997 - - 1.089e-208 660.0
PYH3_k127_3427336_10 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily K06991 - - 0.0000000000000000000000000000000000000000000000000000000004311 205.0
PYH3_k127_3427336_11 DNA-templated transcription, initiation K03088 - - 0.0000000000000000000000000000000000000000000000000000003355 205.0
PYH3_k127_3427336_12 Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated K00567 - 2.1.1.63 0.0000000000000000000000000000000000000000000002301 175.0
PYH3_k127_3427336_13 Transcriptional regulator containing an HTH domain fused to a Zn-ribbon K07743 - - 0.00000000000000000000000001495 112.0
PYH3_k127_3427336_15 - - - - 0.00000000000000009176 82.0
PYH3_k127_3427336_17 PFAM SH3, type 3 - - - 0.000000000004532 79.0
PYH3_k127_3427336_2 Endonuclease/Exonuclease/phosphatase family K01142 - 3.1.11.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000558 412.0
PYH3_k127_3427336_3 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000632 337.0
PYH3_k127_3427336_4 Cache domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006581 294.0
PYH3_k127_3427336_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006633 273.0
PYH3_k127_3427336_6 Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors K03814 - 2.4.1.129 0.00000000000000000000000000000000000000000000000000000000000000000004624 237.0
PYH3_k127_3427336_7 transmembrane transport - - - 0.0000000000000000000000000000000000000000000000000000000000000001096 231.0
PYH3_k127_3427336_8 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000009939 226.0
PYH3_k127_3427336_9 rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality K07560 GO:0002161,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006399,GO:0006450,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0034641,GO:0034660,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0051499,GO:0051500,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0106074,GO:0140098,GO:0140101,GO:1901360 - 0.000000000000000000000000000000000000000000000000000000000116 206.0
PYH3_k127_3463138_0 FAD binding domain K00278 - 1.4.3.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001997 529.0
PYH3_k127_3463138_1 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 419.0
PYH3_k127_3463138_2 Anthranilate synthase component I K01657,K01665,K03342,K13950 - 2.6.1.85,4.1.3.27,4.1.3.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007405 404.0
PYH3_k127_3463138_3 it plays a direct role in the translocation of protons across the membrane K02108 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001715 390.0
PYH3_k127_3463138_4 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826,K02619 - 2.6.1.42,4.1.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003982 358.0
PYH3_k127_3463138_5 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02110 - - 0.000000000000000000000000000000000003407 138.0
PYH3_k127_3463138_6 function for this protein is to guide the assembly of the membrane sector of the ATPase enzyme complex K02116 - - 0.0000000000000000000000000002368 117.0
PYH3_k127_3502485_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 0.0 1027.0
PYH3_k127_3502485_1 aerobic electron transport chain K00425,K08738 - 1.10.3.14 1.705e-321 989.0
PYH3_k127_3502485_10 oxidoreductase activity, acting on diphenols and related substances as donors K00240,K03886 - 1.3.5.1,1.3.5.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004352 468.0
PYH3_k127_3502485_11 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172 - 1.2.7.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001143 436.0
PYH3_k127_3502485_12 Cytochrome c K02305,K07152 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000133 434.0
PYH3_k127_3502485_13 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit K02500 GO:0000107,GO:0003674,GO:0003824,GO:0016740,GO:0016757,GO:0016763 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001357 421.0
PYH3_k127_3502485_14 PFAM metal-dependent phosphohydrolase, HD sub domain K01524,K07012 - 3.6.1.11,3.6.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004416 409.0
PYH3_k127_3502485_15 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001487 377.0
PYH3_k127_3502485_16 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005189 362.0
PYH3_k127_3502485_17 Ethylbenzene dehydrogenase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003957 346.0
PYH3_k127_3502485_18 IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR K02501 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004845 316.0
PYH3_k127_3502485_19 Cytochrome c K17052 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001019 312.0
PYH3_k127_3502485_2 Pyruvate:ferredoxin oxidoreductase core domain II K00169 - 1.2.7.1 2.219e-256 792.0
PYH3_k127_3502485_20 Cytochrome c K08738 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002879 304.0
PYH3_k127_3502485_21 Phosphoribosyl-AMP cyclohydrolase K01496,K11755 - 3.5.4.19,3.6.1.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000007769 296.0
PYH3_k127_3502485_22 UbiA prenyltransferase family K03179 - 2.5.1.39 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000006079 294.0
PYH3_k127_3502485_23 Imidazoleglycerol-phosphate dehydratase K01693 GO:0000105,GO:0003674,GO:0003824,GO:0004424,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016829,GO:0016835,GO:0016836,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 4.2.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000003563 294.0
PYH3_k127_3502485_24 Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity K00765 GO:0000105,GO:0003674,GO:0003824,GO:0003879,GO:0006082,GO:0006520,GO:0006547,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001309 281.0
PYH3_k127_3502485_25 Histidine biosynthesis protein K01814 GO:0000105,GO:0000162,GO:0003674,GO:0003824,GO:0003949,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006547,GO:0006568,GO:0006576,GO:0006586,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009308,GO:0009309,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0018130,GO:0019438,GO:0019752,GO:0034641,GO:0042401,GO:0042430,GO:0042435,GO:0043436,GO:0044106,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046219,GO:0046394,GO:0046483,GO:0052803,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.16 0.000000000000000000000000000000000000000000000000000000000000000000000000000002127 268.0
PYH3_k127_3502485_26 Cytochrome c - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000008932 265.0
PYH3_k127_3502485_27 Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif K02493 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0016740,GO:0016741,GO:0032259,GO:0044424,GO:0044444,GO:0044464 2.1.1.297 0.00000000000000000000000000000000000000000000000000000000000000000000000003042 261.0
PYH3_k127_3502485_28 Uncharacterised protein family UPF0047 - - - 0.0000000000000000000000000000000000000000000000000000000000008035 216.0
PYH3_k127_3502485_3 Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template K03628 - - 1.012e-255 792.0
PYH3_k127_3502485_30 Oxidoreductase - - - 0.0000000000000000000000000000000000000000000000001419 177.0
PYH3_k127_3502485_31 - - - - 0.000000000000000000000000000000000000000000006475 166.0
PYH3_k127_3502485_32 Uncharacterized conserved protein (DUF2203) - - - 0.0000000000000000000000000000000000000000004323 162.0
PYH3_k127_3502485_33 Scavenger mRNA decapping enzyme C-term binding K02503 - - 0.0000000000000000000000000000000000000000008368 164.0
PYH3_k127_3502485_35 Binds the 23S rRNA K02909 - - 0.0000000000000000000000000000003688 124.0
PYH3_k127_3502485_36 Evidence 5 No homology to any previously reported sequences K07126 - - 0.00000000000000000000000000005172 124.0
PYH3_k127_3502485_38 YCII-related domain K09780 - - 0.00000000000000000001118 94.0
PYH3_k127_3502485_39 PFAM IS1 transposase K07480 - - 0.000000000000001083 82.0
PYH3_k127_3502485_4 Cytochrome b/b6/petB K00412 - - 1.583e-220 685.0
PYH3_k127_3502485_40 PFAM IS1 transposase K07480 - - 0.00000002817 55.0
PYH3_k127_3502485_41 TPR repeat - - - 0.00004077 56.0
PYH3_k127_3502485_5 Domain of unknown function (DUF3463) - - - 5.331e-202 630.0
PYH3_k127_3502485_6 Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine K00013 - 1.1.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 627.0
PYH3_k127_3502485_7 Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine K00790 - 2.5.1.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000279 605.0
PYH3_k127_3502485_8 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170 - 1.2.7.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002246 573.0
PYH3_k127_3502485_9 Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA K02835 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 473.0
PYH3_k127_3632414_0 sulfate adenylyltransferase (ATP) activity K00860,K00955,K00956 - 2.7.1.25,2.7.7.4 1.474e-283 879.0
PYH3_k127_3632414_1 NeuB family K03856 - 2.5.1.54 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001061 602.0
PYH3_k127_3632414_10 Membrane - - - 0.000000000000000000000000000000000000000000000000000000000000000000005289 242.0
PYH3_k127_3632414_11 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.0000000000000000000000000000000000000000000003523 168.0
PYH3_k127_3632414_2 Chorismate mutase type II K14170 - 4.2.1.51,5.4.99.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006199 589.0
PYH3_k127_3632414_3 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing K03551 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000154 546.0
PYH3_k127_3632414_4 Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily K00817 - 2.6.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003409 540.0
PYH3_k127_3632414_5 protein tyrosine kinase activity K03593 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009627 527.0
PYH3_k127_3632414_6 Prephenate dehydrogenase K04517 - 1.3.1.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000489 443.0
PYH3_k127_3632414_7 Transcriptional regulator - GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003657 424.0
PYH3_k127_3632414_8 Proto-chlorophyllide reductase 57 kd subunit - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000349 384.0
PYH3_k127_3632414_9 The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB K03550 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000000002075 242.0
PYH3_k127_368456_0 molybdopterin cofactor binding K00370,K10700,K16964,K17050 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.17.99.2,1.7.5.1,1.8.2.4 0.0 2222.0
PYH3_k127_368456_1 Glycine cleavage system P-protein K00281,K00283 - 1.4.4.2 0.0 1430.0
PYH3_k127_368456_10 Belongs to the GPI family K01810 - 5.3.1.9 3.607e-264 824.0
PYH3_k127_368456_11 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.421e-260 813.0
PYH3_k127_368456_12 radical SAM domain protein - - - 1.114e-251 790.0
PYH3_k127_368456_13 Beta-Casp domain K07576 - - 2.333e-228 723.0
PYH3_k127_368456_14 Sulfate permease family - - - 1.305e-221 710.0
PYH3_k127_368456_15 Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12 K14441 - 2.8.4.4 1.163e-216 679.0
PYH3_k127_368456_16 Belongs to the GPI family K01810,K13810 - 2.2.1.2,5.3.1.9 2.044e-216 687.0
PYH3_k127_368456_17 Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins K03217 - - 5.788e-211 669.0
PYH3_k127_368456_18 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001388 578.0
PYH3_k127_368456_19 aminopeptidase activity K01266 - 3.4.11.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 552.0
PYH3_k127_368456_2 Peptidase family M1 domain K08776 - - 0.0 1068.0
PYH3_k127_368456_20 Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 K00566 - 2.8.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009148 517.0
PYH3_k127_368456_21 Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 K03650 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002389 506.0
PYH3_k127_368456_22 Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP-PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions K21071 - 2.7.1.11,2.7.1.90 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002387 501.0
PYH3_k127_368456_23 Glucokinase K00845 - 2.7.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004002 475.0
PYH3_k127_368456_24 Class V aminotransferase K04127 - 5.1.1.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001253 467.0
PYH3_k127_368456_25 ATPase family associated with various cellular activities (AAA) K03924 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008368 451.0
PYH3_k127_368456_26 FIST C domain - GO:0008150,GO:0040007 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003083 456.0
PYH3_k127_368456_27 Fructose-bisphosphate aldolase class-I K01623 - 4.1.2.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001259 434.0
PYH3_k127_368456_28 aldehyde-lyase activity K01621 - 4.1.2.22,4.1.2.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008365 424.0
PYH3_k127_368456_29 Divalent cation transporter K06213 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004693 430.0
PYH3_k127_368456_3 FtsX-like permease family K02004 - - 0.0 1060.0
PYH3_k127_368456_30 Polyphosphate kinase 2 (PPK2) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003831 420.0
PYH3_k127_368456_31 Possible lysine decarboxylase K06966 - 3.2.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002524 400.0
PYH3_k127_368456_32 Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex K02115 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001445 381.0
PYH3_k127_368456_34 Cellulose biosynthesis protein BcsQ K03496 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 345.0
PYH3_k127_368456_35 Aminomethyltransferase folate-binding domain K00605 - 2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003712 346.0
PYH3_k127_368456_36 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005862 343.0
PYH3_k127_368456_37 lipoprotein transporter activity K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002519 322.0
PYH3_k127_368456_38 ParB-like nuclease domain K03497 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009179 310.0
PYH3_k127_368456_39 protein (some members contain a von Willebrand factor type A (vWA) domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003115 310.0
PYH3_k127_368456_4 Belongs to the transketolase family K00615 - 2.2.1.1 1.265e-321 996.0
PYH3_k127_368456_40 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K00851,K00852,K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 2.7.1.12,2.7.1.15,5.3.1.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 298.0
PYH3_k127_368456_41 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002076 278.0
PYH3_k127_368456_42 2OG-Fe(II) oxygenase superfamily K07394 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003823 267.0
PYH3_k127_368456_43 Glucosamine-6-phosphate isomerases/6-phosphogluconolactonase K01057 - 3.1.1.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000001843 268.0
PYH3_k127_368456_44 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000219 262.0
PYH3_k127_368456_45 lipolytic protein G-D-S-L family K10804 GO:0003674,GO:0003824,GO:0004620,GO:0004622,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016289,GO:0016290,GO:0016298,GO:0016787,GO:0016788,GO:0016790,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0042802,GO:0043170,GO:0044238,GO:0044464,GO:0047617,GO:0052689,GO:0071704,GO:0140096,GO:1901564 3.1.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000002141 259.0
PYH3_k127_368456_46 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002335 250.0
PYH3_k127_368456_47 NUDIX domain K01515 - 3.6.1.13 0.000000000000000000000000000000000000000000000000000000000000000000001106 243.0
PYH3_k127_368456_48 Protein of unknown function (DUF502) - - - 0.0000000000000000000000000000000000000000000000000000000000000000001139 237.0
PYH3_k127_368456_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00371,K16965,K17048,K17051 GO:0005575,GO:0005623,GO:0042597,GO:0044464 1.7.5.1 5.955e-302 924.0
PYH3_k127_368456_50 Produces ATP from ADP in the presence of a proton gradient across the membrane K02114 GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006163,GO:0006164,GO:0006725,GO:0006753,GO:0006754,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006812,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009141,GO:0009142,GO:0009144,GO:0009145,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009199,GO:0009201,GO:0009205,GO:0009206,GO:0009259,GO:0009260,GO:0009987,GO:0015672,GO:0015985,GO:0015986,GO:0016020,GO:0016469,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0032991,GO:0033178,GO:0034220,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044425,GO:0044464,GO:0045259,GO:0045261,GO:0046034,GO:0046390,GO:0046483,GO:0051179,GO:0051234,GO:0055085,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:0098655,GO:0098660,GO:0098662,GO:0098796,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1902600 - 0.00000000000000000000000000000000000000000000000000000000005134 207.0
PYH3_k127_368456_51 F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation K02113 - - 0.000000000000000000000000000000000000000000000000000000000374 208.0
PYH3_k127_368456_53 acetyltransferase - - - 0.0000000000000000000000000000000000000000000000000000112 194.0
PYH3_k127_368456_54 3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase K01247 - 3.2.2.21 0.00000000000000000000000000000000000000000000000000005331 194.0
PYH3_k127_368456_55 Polymer-forming cytoskeletal - - - 0.00000000000000000000000000000000000000000000003244 174.0
PYH3_k127_368456_56 RF-1 domain K15034 - - 0.000000000000000000000000000000000000000000004513 166.0
PYH3_k127_368456_57 Polymer-forming cytoskeletal - - - 0.000000000000000000000000000000000000000000004611 168.0
PYH3_k127_368456_58 L,D-transpeptidase catalytic domain - - - 0.000000000000000000000000000000000000000001622 164.0
PYH3_k127_368456_59 Specifically methylates the N7 position of a guanine in 16S rRNA K03501 - 2.1.1.170 0.00000000000000000000000000000000001082 143.0
PYH3_k127_368456_6 NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 K03495 GO:0000166,GO:0001510,GO:0002097,GO:0002098,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036094,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0050660,GO:0050662,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901363 - 7.679e-294 912.0
PYH3_k127_368456_60 Iron-binding zinc finger CDGSH type - - - 0.00000000000000000000000000000004376 127.0
PYH3_k127_368456_61 tetraacyldisaccharide 4'-kinase activity K09791 - - 0.0000000000000000000000000000236 119.0
PYH3_k127_368456_66 ribonuclease P activity K03536,K08998 GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005655,GO:0005730,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0030681,GO:0031123,GO:0031404,GO:0031974,GO:0031981,GO:0032991,GO:0033204,GO:0034414,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0040007,GO:0042301,GO:0042779,GO:0042780,GO:0042781,GO:0043167,GO:0043168,GO:0043170,GO:0043199,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043628,GO:0044237,GO:0044238,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044452,GO:0044464,GO:0046483,GO:0070013,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901681,GO:1902494,GO:1902555,GO:1905267,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000000293 103.0
PYH3_k127_368456_67 Could be involved in insertion of integral membrane proteins into the membrane K08998 - - 0.00000000000000000000008975 104.0
PYH3_k127_368456_68 energy transducer activity K03832 - - 0.0000000000000000002051 99.0
PYH3_k127_368456_69 - - - - 0.00000000000000091 86.0
PYH3_k127_368456_7 Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit K02111 - 3.6.3.14 2.503e-292 902.0
PYH3_k127_368456_70 - - - - 0.000000000000009422 78.0
PYH3_k127_368456_72 Belongs to the bacterial ribosomal protein bL34 family K02914 - - 0.0000000005511 60.0
PYH3_k127_368456_73 DNA integration - - - 0.0000008931 52.0
PYH3_k127_368456_8 Fumarate reductase flavoprotein C-term K00239 - 1.3.5.1,1.3.5.4 2.853e-286 886.0
PYH3_k127_368456_9 Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits K02112 - 3.6.3.14 3.09e-283 873.0
PYH3_k127_3847571_0 that it carries out the mismatch recognition step. This protein has a weak ATPase activity K03555 GO:0003674,GO:0003676,GO:0003677,GO:0003684,GO:0003690,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0030983,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 0.0 1083.0
PYH3_k127_3847571_1 Aminotransferase class I and II K14261 - - 1.73e-232 722.0
PYH3_k127_3847571_11 Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein K00997 - 2.7.8.7 0.0000000000000000000000000000911 120.0
PYH3_k127_3847571_12 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase - - - 0.00000000000000000000000005767 111.0
PYH3_k127_3847571_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 1.58e-207 659.0
PYH3_k127_3847571_3 Insulinase (Peptidase family M16) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006854 526.0
PYH3_k127_3847571_4 Homoserine dehydrogenase K00003 - 1.1.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001356 502.0
PYH3_k127_3847571_5 Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate K03474 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008150,GO:0008152,GO:0008614,GO:0008615,GO:0009058,GO:0009110,GO:0009987,GO:0016740,GO:0016769,GO:0017144,GO:0018130,GO:0019438,GO:0033856,GO:0034641,GO:0042364,GO:0042816,GO:0042819,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:0072524,GO:0072525,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 2.6.99.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003391 344.0
PYH3_k127_3847571_8 Hit family K19710 - 2.7.7.53 0.000000000000000000000000000000000000000000000000000000001374 206.0
PYH3_k127_3847571_9 Threonylcarbamoyl adenosine biosynthesis protein TsaE K06925 - - 0.000000000000000000000000000000000000000007752 160.0
PYH3_k127_3861359_0 Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine K01733 - 4.2.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003396 581.0
PYH3_k127_3861359_1 FAD binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005345 580.0
PYH3_k127_3861359_10 ThiS family K03636 - - 0.0000000000000000000000000000000000000001114 152.0
PYH3_k127_3861359_11 JAB/MPN domain K21140 - 3.13.1.6 0.000000000000000000000000000000000000002632 152.0
PYH3_k127_3861359_12 NIL - - - 0.00000000000000000000000000000000002633 141.0
PYH3_k127_3861359_15 thiamine diphosphate biosynthetic process K03154 - - 0.00000000000000000000001711 100.0
PYH3_k127_3861359_17 Cache domain - - - 0.00000000000003613 85.0
PYH3_k127_3861359_2 Pyridoxal-phosphate dependent enzyme K01738,K12339 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003894 556.0
PYH3_k127_3861359_3 ThiF family K21029 - 2.7.7.80 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001136 458.0
PYH3_k127_3861359_4 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009677 445.0
PYH3_k127_3861359_5 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000005185 278.0
PYH3_k127_3861359_6 nucleotidyltransferase activity K00984,K19279 - 2.7.7.47 0.00000000000000000000000000000000000000000000000000000000000000000000003556 249.0
PYH3_k127_3861359_7 PLD-like domain - - - 0.00000000000000000000000000000000000000000000000000000000001749 212.0
PYH3_k127_3861359_9 - - - - 0.00000000000000000000000000000000000000000000000000005449 195.0
PYH3_k127_3912863_0 amine dehydrogenase activity - - - 0.0 1630.0
PYH3_k127_3912863_1 Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn) K01876 - 6.1.1.12 7.483e-319 987.0
PYH3_k127_3912863_10 Predicted permease YjgP/YjgQ family K11720 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005617 402.0
PYH3_k127_3912863_11 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain K00015 - 1.1.1.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004691 379.0
PYH3_k127_3912863_12 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002583 346.0
PYH3_k127_3912863_13 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002466 349.0
PYH3_k127_3912863_14 Protein kinase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004997 249.0
PYH3_k127_3912863_16 'Cold-shock' DNA-binding domain K03704 - - 0.00000000000000000000000000000000003962 134.0
PYH3_k127_3912863_17 PFAM metal-dependent phosphohydrolase, HD sub domain K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000006406 138.0
PYH3_k127_3912863_18 Carrier of the growing fatty acid chain in fatty acid biosynthesis K02078,K05553 - - 0.000000000000000000000001047 107.0
PYH3_k127_3912863_19 - - - - 0.00000000000000000002021 93.0
PYH3_k127_3912863_2 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 1.095e-280 869.0
PYH3_k127_3912863_20 Staphylococcal nuclease homologues K01174 - 3.1.31.1 0.00000000000000000004483 98.0
PYH3_k127_3912863_21 Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase K09862 - - 0.000000000000005589 76.0
PYH3_k127_3912863_22 - - - - 0.00000000008981 63.0
PYH3_k127_3912863_3 Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth K00088 - 1.1.1.205 3.879e-262 814.0
PYH3_k127_3912863_4 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP K09458 - 2.3.1.179 4.916e-211 662.0
PYH3_k127_3912863_5 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide K00387 - 1.8.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005315 529.0
PYH3_k127_3912863_6 HI0933-like protein K07007 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 497.0
PYH3_k127_3912863_7 Predicted permease YjgP/YjgQ family K07091 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002443 471.0
PYH3_k127_3912863_8 Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K02536 - 2.3.1.191 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000728 457.0
PYH3_k127_3912863_9 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005897 421.0
PYH3_k127_3928026_0 Belongs to the DegT DnrJ EryC1 family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009317 402.0
PYH3_k127_3928026_1 LmbE homologs - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000865 255.0
PYH3_k127_3928026_2 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000007415 243.0
PYH3_k127_3928026_3 Glycosyl transferase family 4 K02851 - 2.7.8.33,2.7.8.35 0.00000000000000000000000000000000000000000000003472 181.0
PYH3_k127_3976583_0 Glycosyl transferase, family 2 K10012,K12999,K13670 - 2.4.2.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000588 433.0
PYH3_k127_3976583_1 WbqC-like protein family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001736 300.0
PYH3_k127_3976583_2 trans-aconitate 2-methyltransferase activity K02169 GO:0002682,GO:0002683,GO:0006629,GO:0006643,GO:0006664,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009247,GO:0009605,GO:0009607,GO:0009987,GO:0031347,GO:0031348,GO:0035821,GO:0043207,GO:0044003,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044403,GO:0044413,GO:0044414,GO:0044419,GO:0045088,GO:0045824,GO:0046467,GO:0048519,GO:0048583,GO:0048585,GO:0050776,GO:0050777,GO:0050789,GO:0050896,GO:0051701,GO:0051704,GO:0051707,GO:0051817,GO:0051832,GO:0051833,GO:0052031,GO:0052037,GO:0052167,GO:0052170,GO:0052173,GO:0052200,GO:0052255,GO:0052261,GO:0052306,GO:0052309,GO:0052552,GO:0052553,GO:0052561,GO:0052562,GO:0052564,GO:0052572,GO:0065007,GO:0071704,GO:0075136,GO:0080134,GO:1901135,GO:1901137,GO:1901576,GO:1903509 2.1.1.197 0.0000000000000000000000000000000000000000000000000000000000000000000006616 243.0
PYH3_k127_3976583_3 Glycosyltransferase Family 4 - - - 0.0000000001375 63.0
PYH3_k127_3976583_4 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.00000003031 56.0
PYH3_k127_4019890_0 AAA domain - - - 0.0 1089.0
PYH3_k127_4019890_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 0.0 1040.0
PYH3_k127_4019890_10 Belongs to the Nudix hydrolase family - - - 0.00000000000000000000000000000000000000000501 160.0
PYH3_k127_4019890_11 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000004488 135.0
PYH3_k127_4019890_12 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K12263 - - 0.000000000000000000000000000000005864 133.0
PYH3_k127_4019890_13 His Kinase A (phosphoacceptor) domain - - - 0.0000000000000000000000003332 119.0
PYH3_k127_4019890_15 - - - - 0.0000001051 61.0
PYH3_k127_4019890_2 Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP K00763 GO:0001666,GO:0003674,GO:0003824,GO:0004516,GO:0005575,GO:0005623,GO:0005886,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0006950,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009605,GO:0009607,GO:0009628,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016763,GO:0016874,GO:0016879,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0019674,GO:0034355,GO:0034641,GO:0034654,GO:0036293,GO:0043094,GO:0043173,GO:0043207,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044403,GO:0044419,GO:0044464,GO:0046483,GO:0046496,GO:0047280,GO:0050896,GO:0051186,GO:0051188,GO:0051701,GO:0051704,GO:0051707,GO:0055086,GO:0070482,GO:0071704,GO:0071944,GO:0072524,GO:0072525,GO:0075136,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001674 603.0
PYH3_k127_4019890_3 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008448 598.0
PYH3_k127_4019890_4 very-long-chain-acyl-CoA dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 543.0
PYH3_k127_4019890_5 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001421 464.0
PYH3_k127_4019890_6 AMP binding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000007783 278.0
PYH3_k127_4019890_7 Isochorismatase family K08281,K12132 GO:0003674,GO:0003824,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006766,GO:0006767,GO:0006769,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008198,GO:0008936,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009820,GO:0009987,GO:0016787,GO:0016810,GO:0016811,GO:0017144,GO:0018130,GO:0019362,GO:0019363,GO:0019365,GO:0019438,GO:0019637,GO:0030145,GO:0034641,GO:0034654,GO:0043094,GO:0043167,GO:0043169,GO:0043173,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.11.1,3.5.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000103 247.0
PYH3_k127_4019890_8 regulation of translation K03704,K05809 - - 0.0000000000000000000000000000000000000000000000000000000000000000000976 236.0
PYH3_k127_4019890_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07323 - - 0.0000000000000000000000000000000000000000000000000003346 198.0
PYH3_k127_4091066_0 thiamine transport K02011 - - 2.14e-231 731.0
PYH3_k127_4091066_1 The glycine cleavage system catalyzes the degradation of glycine K00605,K06980,K22086 - 1.5.99.5,2.1.2.10 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001135 521.0
PYH3_k127_4091066_10 photosynthesis - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008193 248.0
PYH3_k127_4091066_12 Belongs to the Fur family K03711 - - 0.0000000000000000000000000000000000000000000000000000000000000000000007383 239.0
PYH3_k127_4091066_13 bacteriocin transport K03561,K03562 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0006810,GO:0008104,GO:0008150,GO:0015031,GO:0015833,GO:0016020,GO:0016021,GO:0017038,GO:0031224,GO:0031226,GO:0033036,GO:0042886,GO:0044425,GO:0044459,GO:0044464,GO:0045184,GO:0051179,GO:0051234,GO:0071702,GO:0071705,GO:0071944 - 0.0000000000000000000000000000000000000000000000000000000000000000863 224.0
PYH3_k127_4091066_14 - - - - 0.00000000000000000000000000000000000000000000000000000000002605 213.0
PYH3_k127_4091066_15 Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell K03282 GO:0003674,GO:0005215,GO:0005575,GO:0006810,GO:0006811,GO:0006884,GO:0008150,GO:0008361,GO:0008381,GO:0009987,GO:0009992,GO:0015267,GO:0016020,GO:0016021,GO:0016043,GO:0019725,GO:0022803,GO:0022836,GO:0022857,GO:0030104,GO:0031224,GO:0032535,GO:0042592,GO:0044425,GO:0048878,GO:0051179,GO:0051234,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0071840,GO:0090066 - 0.0000000000000000000000000000000000000000000000000000001862 211.0
PYH3_k127_4091066_16 GGDEF domain - - - 0.0000000000000000000000000000000000000000000002755 170.0
PYH3_k127_4091066_17 energy transducer activity K03832 - - 0.0000000000000000000000000000005998 133.0
PYH3_k127_4091066_18 Biopolymer transport protein ExbD/TolR K03559 - - 0.000000000000000002451 89.0
PYH3_k127_4091066_2 ATPase activity K02010 - 3.6.3.30 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001581 476.0
PYH3_k127_4091066_3 iron ion homeostasis K02012 GO:0005575,GO:0005623,GO:0042597,GO:0044464 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009499 464.0
PYH3_k127_4091066_4 spore germination - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003905 412.0
PYH3_k127_4091066_5 protein flavinylation K03734 - 2.7.1.180 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007115 401.0
PYH3_k127_4091066_6 cellular water homeostasis K03442,K22044 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002322 328.0
PYH3_k127_4091066_7 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007683 314.0
PYH3_k127_4091066_8 glycerophosphoryl diester phosphodiesterase K01113,K01126 - 3.1.3.1,3.1.4.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000007504 300.0
PYH3_k127_4376432_0 Peptidase dimerisation domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007044 374.0
PYH3_k127_4376432_1 23S rRNA (guanine(2445)-N(2))-methyltransferase activity K07444,K12297 GO:0000154,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008649,GO:0008757,GO:0008990,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016423,GO:0016435,GO:0016740,GO:0016741,GO:0022613,GO:0030488,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0036265,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0070043,GO:0070475,GO:0070476,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140101,GO:0140102,GO:1901360 2.1.1.173,2.1.1.264 0.000000000000000000000000000000000000000000000001121 178.0
PYH3_k127_4376432_2 COG0664 cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases K10914 - - 0.0000000006043 72.0
PYH3_k127_4376432_3 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases - - - 0.0002174 54.0
PYH3_k127_456229_0 phosphorelay signal transduction system K02667 - - 3.655e-224 703.0
PYH3_k127_456229_1 Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring K03590 - - 2.894e-204 644.0
PYH3_k127_456229_10 This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance K02897 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000003436 284.0
PYH3_k127_456229_11 Belongs to the multicopper oxidase YfiH RL5 family K05810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000005085 276.0
PYH3_k127_456229_12 Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis K06997 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006366 253.0
PYH3_k127_456229_13 CDP-alcohol phosphatidyltransferase K08744 - 2.7.8.41 0.0000000000000000000000000000000000000000000000000000000001511 208.0
PYH3_k127_456229_14 ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner K06942 - - 0.0000000000000000000000000000000000000000000000000000000003917 205.0
PYH3_k127_456229_15 DivIVA protein K04074 - - 0.000000000000000000000000000000000000000009485 160.0
PYH3_k127_456229_17 Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly K01921,K03589,K06438 GO:0000003,GO:0000278,GO:0000281,GO:0000910,GO:0000917,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0005887,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0016021,GO:0016043,GO:0019954,GO:0022402,GO:0022414,GO:0022607,GO:0031224,GO:0031226,GO:0032153,GO:0032505,GO:0032506,GO:0040007,GO:0042802,GO:0043093,GO:0044085,GO:0044424,GO:0044425,GO:0044444,GO:0044459,GO:0044464,GO:0051301,GO:0061640,GO:0071840,GO:0071944,GO:0090529,GO:1902410,GO:1903047 6.3.2.4 0.00000000000000000000000000000000000000971 153.0
PYH3_k127_456229_18 YGGT family K02221 - - 0.000000000000000000000000000000000002552 151.0
PYH3_k127_456229_2 phosphorelay sensor kinase activity K02668 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004203 598.0
PYH3_k127_456229_3 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001675 552.0
PYH3_k127_456229_4 Type II secretion system (T2SS), protein F K02455,K02653 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001882 526.0
PYH3_k127_456229_5 Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P) K00948 - 2.7.6.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003364 512.0
PYH3_k127_456229_6 Beta-lactamase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005409 405.0
PYH3_k127_456229_7 Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline K00286 - 1.5.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001658 314.0
PYH3_k127_456229_8 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K01056 GO:0003674,GO:0003824,GO:0004045,GO:0016787,GO:0016788,GO:0052689,GO:0140098,GO:0140101 3.1.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 297.0
PYH3_k127_456229_9 Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol K00919 GO:0003674,GO:0003824,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0044237,GO:0050515 2.7.1.148 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000007735 294.0
PYH3_k127_4649741_0 radical SAM domain protein - - - 2.272e-249 774.0
PYH3_k127_4649741_1 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001652 570.0
PYH3_k127_4649741_2 protein-(glutamine-N5) methyltransferase activity K00543,K16130,K18896,K18897,K21515 - 2.1.1.156,2.1.1.157,2.1.1.209,2.1.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001577 405.0
PYH3_k127_4649741_3 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.00000000000000000009013 91.0
PYH3_k127_4791352_0 MacB-like periplasmic core domain K02004 - - 1.216e-240 771.0
PYH3_k127_4791352_1 Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism K01012 - 2.8.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005875 532.0
PYH3_k127_4791352_2 Catalyzes the conversion of dihydroorotate to orotate K00226,K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14,1.3.98.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004676 498.0
PYH3_k127_4791352_3 lipoprotein transporter activity K02003 - - 0.000000000000000000000000003279 112.0
PYH3_k127_4791352_4 response regulator - - - 0.0000000000000000001237 91.0
PYH3_k127_4791352_5 Tetratricopeptide repeat - - - 0.000000000004329 67.0
PYH3_k127_480999_0 Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE K03695 - - 0.0 1391.0
PYH3_k127_480999_1 Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone K00036 - 1.1.1.363,1.1.1.49 2.173e-250 788.0
PYH3_k127_480999_12 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000001121 114.0
PYH3_k127_480999_13 FecR protein - - - 0.000000000000000003586 98.0
PYH3_k127_480999_14 Recombinase zinc beta ribbon domain - - - 0.00007865 48.0
PYH3_k127_480999_2 Magnesium chelatase, subunit ChlI C-terminal K07391 - - 2.065e-227 713.0
PYH3_k127_480999_3 Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) K01875 - 6.1.1.11 5.005e-208 653.0
PYH3_k127_480999_4 D-gluconate metabolic process K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008931 531.0
PYH3_k127_480999_6 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000003507 253.0
PYH3_k127_480999_7 lipolytic protein G-D-S-L family - - - 0.00000000000000000000000000000000000000000000000000000000006538 211.0
PYH3_k127_480999_9 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K06142 - - 0.00000000000000000000000000000000000000000000000006207 199.0
PYH3_k127_4910723_0 Nitrite and sulphite reductase 4Fe-4S domain K00362,K00392 - 1.7.1.15,1.8.7.1 0.0 1255.0
PYH3_k127_4910723_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 - 6.1.1.3 0.0 1054.0
PYH3_k127_4910723_2 Glycosyl transferase family, a/b domain K00766 - 2.4.2.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006614 440.0
PYH3_k127_4910723_3 sulfate reduction K00390,K00860 GO:0003674,GO:0003824,GO:0004604,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0008152,GO:0016491,GO:0016667,GO:0016671,GO:0044424,GO:0044464,GO:0055114 1.8.4.10,1.8.4.8,2.7.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005308 398.0
PYH3_k127_4910723_4 Translation initiation factor IF-3, C-terminal domain K02520 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 286.0
PYH3_k127_4910723_5 sulfate reduction K00390,K00957 - 1.8.4.10,1.8.4.8,2.7.7.4 0.0000000000000000000000000000000000000000000000000000000000000000000000001479 248.0
PYH3_k127_4910723_6 2 iron, 2 sulfur cluster binding K04487,K13643 - 2.8.1.7 0.00000000000000000000000000000000000000000000000003494 182.0
PYH3_k127_4910723_7 sequence-specific DNA binding K03557,K07712 GO:0000018,GO:0000229,GO:0000785,GO:0000786,GO:0000787,GO:0000789,GO:0000976,GO:0000984,GO:0000985,GO:0001017,GO:0001046,GO:0001047,GO:0001067,GO:0001121,GO:0001130,GO:0001131,GO:0001140,GO:0001216,GO:0001217,GO:0003674,GO:0003676,GO:0003677,GO:0003690,GO:0003700,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005694,GO:0005737,GO:0005829,GO:0006139,GO:0006351,GO:0006355,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008301,GO:0009058,GO:0009059,GO:0009314,GO:0009628,GO:0009889,GO:0009890,GO:0009891,GO:0009892,GO:0009893,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010558,GO:0010604,GO:0010605,GO:0010628,GO:0010629,GO:0016032,GO:0016070,GO:0018130,GO:0019042,GO:0019045,GO:0019046,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031324,GO:0031325,GO:0031326,GO:0031327,GO:0031328,GO:0031421,GO:0032359,GO:0032774,GO:0032991,GO:0032993,GO:0034641,GO:0034645,GO:0034654,GO:0042802,GO:0042803,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043565,GO:0044212,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0044374,GO:0044403,GO:0044419,GO:0044422,GO:0044424,GO:0044427,GO:0044444,GO:0044446,GO:0044464,GO:0044815,GO:0045892,GO:0045893,GO:0045911,GO:0045934,GO:0045935,GO:0046483,GO:0046983,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0050789,GO:0050794,GO:0050896,GO:0051052,GO:0051054,GO:0051171,GO:0051172,GO:0051173,GO:0051252,GO:0051253,GO:0051254,GO:0051704,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1902679,GO:1902680,GO:1903506,GO:1903507,GO:1903508,GO:1990837,GO:2000112,GO:2000113,GO:2001141 - 0.000000000000000000000000000000000000000000000001469 180.0
PYH3_k127_4910723_8 Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit K02887 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015934,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042273,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000000000000000000000000000000000000345 175.0
PYH3_k127_4910723_9 Belongs to the bacterial ribosomal protein bL35 family K02916 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000007323 76.0
PYH3_k127_4919812_0 Aconitase C-terminal domain K01681 - 4.2.1.3 0.0 1368.0
PYH3_k127_4919812_1 Belongs to the citrate synthase family K01902,K15230,K15233 - 2.3.3.8,6.2.1.5 0.0 1112.0
PYH3_k127_4919812_2 Isocitrate dehydrogenase K00031 - 1.1.1.42 8.841e-265 819.0
PYH3_k127_4919812_3 ATP citrate lyase citrate-binding K15231 - 2.3.3.8 1.946e-219 684.0
PYH3_k127_4919812_4 Formamidopyrimidine-DNA glycosylase H2TH domain K10563 - 3.2.2.23,4.2.99.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002028 349.0
PYH3_k127_4919812_6 phosphatase - - - 0.0000000000000000000000000000000000009205 144.0
PYH3_k127_4919858_0 Glycogen debranching enzyme - - - 0.0 1506.0
PYH3_k127_4919858_1 alpha amylase, catalytic region - - - 2.082e-249 777.0
PYH3_k127_4919858_10 Ion channel - - - 0.000000000000000000000000000000000000000000004109 173.0
PYH3_k127_4919858_11 RNA recognition motif - - - 0.000000000000000000000000000000000000000001769 157.0
PYH3_k127_4919858_12 ABC-type transport auxiliary lipoprotein component - - - 0.00000000000000000000000000000000000000004658 162.0
PYH3_k127_4919858_13 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000001412 162.0
PYH3_k127_4919858_14 modulation by symbiont of host adenylate cyclase-mediated signal transduction K03775 - 5.2.1.8 0.0000000000000000000000000000000000000002305 155.0
PYH3_k127_4919858_15 Sugar efflux transporter for intercellular exchange - - - 0.000000000000000000000000000000000000001729 150.0
PYH3_k127_4919858_16 OmpA family K02557 - - 0.0000000000000000000000000001319 127.0
PYH3_k127_4919858_17 Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety K03286 - - 0.0001509 53.0
PYH3_k127_4919858_2 MlaD protein K06192 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001375 560.0
PYH3_k127_4919858_3 S-adenosylmethionine-dependent methyltransferase K06969 - 2.1.1.191 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 511.0
PYH3_k127_4919858_4 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000003854 275.0
PYH3_k127_4919858_5 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001576 277.0
PYH3_k127_4919858_6 Type II secretory pathway component ExeA - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001656 269.0
PYH3_k127_4919858_7 Peptidase family M48 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005858 273.0
PYH3_k127_4919858_8 paraquat-inducible protein A K03808 - - 0.000000000000000000000000000000000000000000000000000000000000007029 222.0
PYH3_k127_4919858_9 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000001483 174.0
PYH3_k127_4951781_0 NHL repeat - - - 7.295e-241 747.0
PYH3_k127_4951781_1 denitrification pathway - - - 7.512e-209 657.0
PYH3_k127_4951781_2 denitrification pathway - - - 9.414e-199 626.0
PYH3_k127_4951781_3 radical SAM domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008609 494.0
PYH3_k127_4951781_4 chaperone-mediated protein complex assembly K00373,K17052 GO:0003674,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016530,GO:0022607,GO:0034622,GO:0042126,GO:0042128,GO:0043436,GO:0043933,GO:0044085,GO:0044237,GO:0044281,GO:0044424,GO:0044464,GO:0051131,GO:0065003,GO:0071704,GO:0071840,GO:0071941,GO:0140104,GO:2001057 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 455.0
PYH3_k127_4951781_5 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003112 428.0
PYH3_k127_4951781_9 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system K03116 - - 0.00000000000000000000001385 103.0
PYH3_k127_4954616_0 cyclic 2,3-diphosphoglycerate synthetase activity K05716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001596 578.0
PYH3_k127_4954616_1 Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000253 370.0
PYH3_k127_4954616_2 Predicted nucleotidyltransferase K07074 - - 0.000000000000000000000000000000000000000001706 164.0
PYH3_k127_4968420_0 Glycosyl hydrolase family 57 - - - 5.147e-305 950.0
PYH3_k127_4968420_1 Galactose-1-phosphate uridyl transferase, N-terminal domain K00965 - 2.7.7.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 565.0
PYH3_k127_4968420_2 Adenylyl cyclase class-3 4 guanylyl cyclase K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001201 558.0
PYH3_k127_4968420_3 Phosphotransferase enzyme family K07102 - 2.7.1.221 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002762 457.0
PYH3_k127_4968420_4 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007233 340.0
PYH3_k127_4968420_5 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000000000000000000000000000000000000000000000000000000000000001045 256.0
PYH3_k127_5026772_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1487.0
PYH3_k127_5026772_1 Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction K03147 - 4.1.99.17 1.651e-318 984.0
PYH3_k127_5026772_10 MraZ protein, putative antitoxin-like K03925 - - 0.0000000000000000000000000000000000000000000002412 168.0
PYH3_k127_5026772_11 crossover junction endodeoxyribonuclease activity K01160 - 3.1.22.4 0.0000000000000000000000000000000000000000000279 173.0
PYH3_k127_5026772_13 Helix-hairpin-helix motif - - - 0.00004194 54.0
PYH3_k127_5026772_2 Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate K03517 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006531,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008987,GO:0009058,GO:0009066,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0016053,GO:0017144,GO:0018130,GO:0019355,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0019752,GO:0019805,GO:0034627,GO:0034628,GO:0034641,GO:0034654,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046496,GO:0046874,GO:0048037,GO:0051186,GO:0051188,GO:0051536,GO:0051539,GO:0051540,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.5.1.72 4.659e-210 658.0
PYH3_k127_5026772_3 MacB-like periplasmic core domain K02004 - - 4.454e-205 644.0
PYH3_k127_5026772_4 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K02005 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 501.0
PYH3_k127_5026772_5 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 GO:0003674,GO:0005488,GO:0005506,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009987,GO:0017144,GO:0018130,GO:0018131,GO:0019438,GO:0034641,GO:0042364,GO:0042723,GO:0042724,GO:0043167,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046484,GO:0046872,GO:0046914,GO:0052837,GO:0052838,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006409 488.0
PYH3_k127_5026772_6 Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP) K06153 - 3.6.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009076 350.0
PYH3_k127_5026772_7 Evidence 2b Function of strongly homologous gene K02003 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007914 333.0
PYH3_k127_5026772_8 This protein specifically catalyzes the removal of signal peptides from prolipoproteins K03101 - 3.4.23.36 0.0000000000000000000000000000000000000000000000000000000000000006118 225.0
PYH3_k127_5026772_9 photosynthesis - - - 0.000000000000000000000000000000000000000000000000000000000005947 211.0
PYH3_k127_5041739_0 FAD binding domain K00239 - 1.3.5.1,1.3.5.4 1.936e-288 891.0
PYH3_k127_5041739_1 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002113 587.0
PYH3_k127_5041739_2 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001707 523.0
PYH3_k127_5041739_3 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001879 415.0
PYH3_k127_5087053_0 Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs K04094 - 2.1.1.74 7.635e-226 708.0
PYH3_k127_5087053_1 Belongs to the acetylglutamate kinase family. ArgB subfamily K00930 - 2.7.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005027 470.0
PYH3_k127_5087053_10 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.00000000000000000000000000000000003497 139.0
PYH3_k127_5087053_11 Saccharopine dehydrogenase NADP binding domain K00290 - 1.5.1.7 0.00000000000000000000000000000002528 140.0
PYH3_k127_5087053_13 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.000000000000000000000000001496 119.0
PYH3_k127_5087053_2 May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO K06187 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001346 351.0
PYH3_k127_5087053_3 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003231 347.0
PYH3_k127_5087053_4 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304 - 1.8.4.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 286.0
PYH3_k127_5087053_6 Bacterial transferase hexapeptide (six repeats) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002423 266.0
PYH3_k127_5087053_7 Peptidase family M28 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000004329 251.0
PYH3_k127_5087053_8 tyrosine recombinase XerC K03733,K04763 - - 0.0000000000000000000000000000000000000000000000000000000004485 223.0
PYH3_k127_5087053_9 Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection K09747 - - 0.00000000000000000000000000000000000001047 148.0
PYH3_k127_5227872_0 Amino acid permease K03294 - - 3.936e-230 729.0
PYH3_k127_5227872_1 Pfam Adenylate and Guanylate cyclase catalytic domain K01768 - 4.6.1.1 0.00000000000000000000000000000000000000000000000000000000000003976 231.0
PYH3_k127_5227872_2 Peptidase C26 K07010 - - 0.0000000000000000000000000000000000000000000000000008355 192.0
PYH3_k127_5234984_0 - - - - 9.015e-270 841.0
PYH3_k127_5234984_1 ATPase activity K02017,K02018,K03750,K15497 - 2.10.1.1,3.6.3.29,3.6.3.55 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004817 397.0
PYH3_k127_5234984_2 Bacterial extracellular solute-binding protein K02020 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 334.0
PYH3_k127_5234984_3 PFAM binding-protein-dependent transport systems inner membrane component K02018 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000005442 283.0
PYH3_k127_5256980_0 Nitroreductase - - - 4.254e-243 763.0
PYH3_k127_5256980_1 serine threonine protein kinase K12132 - 2.7.11.1 7.93e-224 721.0
PYH3_k127_5256980_10 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000002061 170.0
PYH3_k127_5256980_11 Domain of unknown function (DUF3393) - - - 0.0000000000000000000000000000000001497 153.0
PYH3_k127_5256980_15 - - - - 0.0003164 47.0
PYH3_k127_5256980_2 FAD binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002125 594.0
PYH3_k127_5256980_3 helicase superfamily c-terminal domain K11927 - 3.6.4.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004495 591.0
PYH3_k127_5256980_4 lytic transglycosylase activity K08306,K08308,K08309 GO:0000270,GO:0003674,GO:0003824,GO:0005575,GO:0005623,GO:0006022,GO:0006026,GO:0006027,GO:0006807,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0008932,GO:0008933,GO:0009056,GO:0009057,GO:0009253,GO:0009279,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0019867,GO:0030203,GO:0030288,GO:0030312,GO:0030313,GO:0031224,GO:0031225,GO:0031975,GO:0033554,GO:0034599,GO:0042221,GO:0042597,GO:0043170,GO:0044425,GO:0044462,GO:0044464,GO:0046677,GO:0050896,GO:0051716,GO:0061783,GO:0070887,GO:0071236,GO:0071704,GO:0071944,GO:1901135,GO:1901136,GO:1901564,GO:1901565,GO:1901575 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001194 527.0
PYH3_k127_5256980_5 Permease MlaE K02066 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007706 312.0
PYH3_k127_5256980_6 MlaD protein K02067 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002674 307.0
PYH3_k127_5256980_8 histone H2A K63-linked ubiquitination - - - 0.00000000000000000000000000000000000000000000000007696 186.0
PYH3_k127_5256980_9 ATPase activity K02065 - - 0.000000000000000000000000000000000000000000000001626 182.0
PYH3_k127_5284690_0 formate dehydrogenase, alpha subunit K00123 - 1.17.1.9 2.393e-258 826.0
PYH3_k127_5284690_1 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00124,K00335 - 1.6.5.3 1.195e-230 722.0
PYH3_k127_5284690_10 hemerythrin HHE cation binding domain - - - 0.000000000000000000000000000000000000000000000001409 179.0
PYH3_k127_5284690_11 Thioredoxin-like [2Fe-2S] ferredoxin K00334 - 1.6.5.3 0.00000000000000000000000000000000000000000001265 166.0
PYH3_k127_5284690_12 thiolester hydrolase activity K07100 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000009567 144.0
PYH3_k127_5284690_3 formate transmembrane transporter activity K02598,K06212,K21993 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000201 367.0
PYH3_k127_5284690_4 AMP binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001624 320.0
PYH3_k127_5284690_6 Belongs to the universal stress protein A family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006928 289.0
PYH3_k127_5284690_7 Phosphomethylpyrimidine kinase K16370 - 2.7.1.11 0.00000000000000000000000000000000000000000000000000000000000000000008324 241.0
PYH3_k127_5284690_8 Universal stress protein family - - - 0.00000000000000000000000000000000000000000000000000000000001024 210.0
PYH3_k127_5284690_9 Cytochrome c - - - 0.00000000000000000000000000000000000000000000000000000000019 205.0
PYH3_k127_5379457_0 NmrA-like family K00091 - 1.1.1.219 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005381 526.0
PYH3_k127_5379457_1 Polyprenyl synthetase K13789 - 2.5.1.1,2.5.1.10,2.5.1.29 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001373 474.0
PYH3_k127_5379457_2 Carotenoid biosynthesis protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 325.0
PYH3_k127_5379457_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000005549 244.0
PYH3_k127_5379457_4 Cytochrome c K03611 - - 0.00000000000000000000000000000000000000000000000000000000000000000006681 236.0
PYH3_k127_5379457_8 Mycobacterial 4 TMS phage holin, superfamily IV K08972 - - 0.00000000000000000000002641 103.0
PYH3_k127_5887739_0 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.964e-287 898.0
PYH3_k127_5887739_1 Cytochrome b/b6/petB K00412,K03888 - - 5.346e-236 738.0
PYH3_k127_5887739_10 S23 ribosomal protein - - - 0.0000000000000000000000000000009528 124.0
PYH3_k127_5887739_12 Cytochrome c K12263 - - 0.00000000000000001895 88.0
PYH3_k127_5887739_2 Cytochrome c K12263 - - 8.7e-201 633.0
PYH3_k127_5887739_3 6-phosphogluconate dehydrogenase, C-terminal domain K00033 - 1.1.1.343,1.1.1.44 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006423 556.0
PYH3_k127_5887739_4 cyclic nucleotide binding K01420,K10914,K21556,K21562 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001338 285.0
PYH3_k127_5887739_5 Rieske [2Fe-2S] domain K02636,K03886 - 1.10.9.1 0.0000000000000000000000000000000000000000000000000000000000000000000000004851 250.0
PYH3_k127_5887739_6 signal-transduction protein containing cAMP-binding and CBS domains K10716 - - 0.00000000000000000000000000000000000000000000000000000000000000000000002 252.0
PYH3_k127_5887739_7 OsmC-like protein K09136 - - 0.00000000000000000000000000000000000000000000000000000009612 198.0
PYH3_k127_5887739_8 integral membrane protein - - - 0.00000000000000000000000000000000000000002225 157.0
PYH3_k127_5887739_9 - - - - 0.000000000000000000000000000000000000002123 160.0
PYH3_k127_608768_0 Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 9.822e-223 698.0
PYH3_k127_608768_1 Histidine kinase K00060,K07777 - 1.1.1.103,2.7.13.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002965 518.0
PYH3_k127_608768_10 alpha-ribazole phosphatase activity - - - 0.000000000000000000000000000000000000000000000000000000003766 205.0
PYH3_k127_608768_11 response regulator, receiver K02479 - - 0.000000000000000000000000000000000000000000000000000000006016 206.0
PYH3_k127_608768_12 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000001516 182.0
PYH3_k127_608768_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005116 476.0
PYH3_k127_608768_3 cellulose binding - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003082 483.0
PYH3_k127_608768_4 Lipocalin-like domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007399 439.0
PYH3_k127_608768_5 Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis K02535 - 3.5.1.108 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007206 398.0
PYH3_k127_608768_6 Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001553 311.0
PYH3_k127_608768_7 ATP-dependent protease La (LON) substrate-binding domain K07157 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002617 284.0
PYH3_k127_608768_8 Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes K07738 - - 0.0000000000000000000000000000000000000000000000000000000000000002933 223.0
PYH3_k127_608768_9 binds to the 23S rRNA K02939 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000005421 210.0
PYH3_k127_6113315_0 Probable RNA and SrmB- binding site of polymerase A K00974 - 2.7.7.72 0.0 1027.0
PYH3_k127_6113315_1 Two component transcriptional regulator, LuxR family - - - 0.0000000000000000000000000000000000000000000000000036 191.0
PYH3_k127_6113315_2 histidine kinase, dimerisation and phosphoacceptor region - - - 0.00000000000000000000161 107.0
PYH3_k127_6113315_3 FecR protein - - - 0.00000000000006857 83.0
PYH3_k127_6113315_4 - - - - 0.000004739 52.0
PYH3_k127_6160391_0 Conserved carboxylase domain K01960 - 6.4.1.1 6.941e-309 956.0
PYH3_k127_6160391_1 Biotin carboxylase C-terminal domain K01959 - 6.4.1.1 8.943e-261 808.0
PYH3_k127_6160391_10 hydrolase activity, acting on ester bonds K01563 - 3.8.1.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001124 354.0
PYH3_k127_6160391_11 phosphate ion binding K02040 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001885 333.0
PYH3_k127_6160391_12 spore germination - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005117 310.0
PYH3_k127_6160391_13 Belongs to the Dps family K04047 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000082 253.0
PYH3_k127_6160391_14 ADP-glyceromanno-heptose 6-epimerase activity K00311 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 1.5.5.1 0.00000000000000000000000000000000000000000000000000000000000000000000000002861 266.0
PYH3_k127_6160391_15 sirohydrochlorin cobaltochelatase activity - - - 0.0000000000000000000000000000000000000000000000000000000002502 207.0
PYH3_k127_6160391_17 Chalcone isomerase-like - - - 0.00000000000000000000000000000000000000000000000000000001298 203.0
PYH3_k127_6160391_18 thioredoxin peroxidase activity K11065 - 1.11.1.15 0.00000000000000000000000000000000000000000000000000000001963 201.0
PYH3_k127_6160391_2 Belongs to the DNA photolyase family K01669 - 4.1.99.3 3.283e-199 632.0
PYH3_k127_6160391_20 light absorption K01822,K21972 - 5.3.3.1 0.00000000000000000000000000000000000009092 153.0
PYH3_k127_6160391_21 Protein of unknown function (DUF2878) - - - 0.000000000000000000000000000000000000299 146.0
PYH3_k127_6160391_22 Copper/zinc superoxide dismutase (SODC) K04565 - 1.15.1.1 0.00000000000000000000000000000000002387 142.0
PYH3_k127_6160391_23 Regulatory protein, FmdB family - - - 0.00000000000000000000000000000004422 128.0
PYH3_k127_6160391_26 Belongs to the peptidase S41A family K03797 - 3.4.21.102 0.000000000000000000000002411 111.0
PYH3_k127_6160391_3 Flavin containing amine oxidoreductase K06954 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004887 591.0
PYH3_k127_6160391_4 PFAM Cyclopropane-fatty-acyl-phospholipid synthase K00574 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000237 540.0
PYH3_k127_6160391_5 Protein of unknown function (DUF1722) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001181 477.0
PYH3_k127_6160391_6 Evidence 4 Homologs of previously reported genes of K18912 - 1.14.99.50 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007697 447.0
PYH3_k127_6160391_7 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000194 372.0
PYH3_k127_6160391_8 Protein of unknown function (DUF1365) K00574,K09701 - 2.1.1.79 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000127 366.0
PYH3_k127_6160391_9 Enoyl-(Acyl carrier protein) reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004561 353.0
PYH3_k127_6174390_0 Aldo Keto reductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000657 548.0
PYH3_k127_6174390_1 response regulator - - - 0.0000000000000000000000000000000003672 138.0
PYH3_k127_61855_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03046 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 2441.0
PYH3_k127_61855_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03043 - 2.7.7.6 0.0 2289.0
PYH3_k127_61855_2 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K02355 - - 0.0 1219.0
PYH3_k127_61855_3 Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit K02950 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000006808 228.0
PYH3_k127_61855_4 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000004028 225.0
PYH3_k127_61855_5 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation K02935 - - 0.0000000000000000000000000000000000004855 141.0
PYH3_k127_61855_6 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000001986 87.0
PYH3_k127_6189255_0 Molydopterin dinucleotide binding domain K00302,K10814 - 1.4.99.5,1.5.3.1 0.0 1376.0
PYH3_k127_6189255_1 NADH-quinone oxidoreductase K00341,K05568,K12139 - 1.6.5.3 0.0 1086.0
PYH3_k127_6189255_10 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00332 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005901 266.0
PYH3_k127_6189255_11 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000002069 227.0
PYH3_k127_6189255_14 ACT domain protein K00003,K00058,K01754,K04767 - 1.1.1.3,1.1.1.399,1.1.1.95,4.3.1.19 0.000000000000000000000000000000000000004592 150.0
PYH3_k127_6189255_15 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 - 1.6.5.3 0.0000000000000000000000007718 106.0
PYH3_k127_6189255_16 PFAM OmpA MotB domain protein K02557 - - 0.000000000000002739 89.0
PYH3_k127_6189255_17 Fatty acid cis/trans isomerase (CTI) - - - 0.00000000003843 63.0
PYH3_k127_6189255_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342,K05575 - 1.6.5.3 3.209e-275 852.0
PYH3_k127_6189255_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 6.884e-262 808.0
PYH3_k127_6189255_4 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 1.328e-240 751.0
PYH3_k127_6189255_5 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 1.6.5.3 5.775e-239 752.0
PYH3_k127_6189255_6 denitrification pathway - - - 2.192e-216 678.0
PYH3_k127_6189255_7 denitrification pathway - - - 1.672e-211 662.0
PYH3_k127_6189255_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001946 336.0
PYH3_k127_6189255_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 332.0
PYH3_k127_61912_0 damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage K03702 - - 0.0 1114.0
PYH3_k127_61912_1 Transglutaminase/protease-like homologues - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002816 353.0
PYH3_k127_61912_2 Ion channel K10716 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000003273 261.0
PYH3_k127_61912_3 Domain of unknown function (DUF4321) - - - 0.000000000000000000000001012 106.0
PYH3_k127_61912_5 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.0000000000000000006709 86.0
PYH3_k127_61912_6 - - - - 0.0001945 46.0
PYH3_k127_6213762_0 NUBPL iron-transfer P-loop NTPase K16554 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006368 452.0
PYH3_k127_6213762_1 Polysaccharide biosynthesis protein K17947 - 5.1.3.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005742 393.0
PYH3_k127_6213762_10 Glycosyl transferase, family 2 - - - 0.00000000000000000000000004019 119.0
PYH3_k127_6213762_11 Competence protein K02238 - - 0.00000000000000000000006526 102.0
PYH3_k127_6213762_12 Polysaccharide biosynthesis protein - - - 0.000000000000000000001091 109.0
PYH3_k127_6213762_13 glycosyl transferase family 2 K00721 - 2.4.1.83 0.000000000000000001058 92.0
PYH3_k127_6213762_14 Methionine biosynthesis protein MetW K00568 - 2.1.1.222,2.1.1.64 0.000000000000000572 90.0
PYH3_k127_6213762_15 Glycosyltransferase family 87 K13671 - - 0.000000000006708 78.0
PYH3_k127_6213762_16 PFAM Polysaccharide export protein K01991 - - 0.000000009136 66.0
PYH3_k127_6213762_17 Glycosyltransferase family 87 K13671 - - 0.0000004701 63.0
PYH3_k127_6213762_2 PFAM Glycosyl transferase, group 1 K08256 - 2.4.1.345 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001159 374.0
PYH3_k127_6213762_3 O-Antigen Polymerase K02847 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000001573 304.0
PYH3_k127_6213762_4 PFAM metal-dependent phosphohydrolase, HD sub domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002976 291.0
PYH3_k127_6213762_5 Glycosyl transferases group 1 - - - 0.000000000000000000000000000000000000000000000000000000000000000001534 242.0
PYH3_k127_6213762_6 Glycosyl transferase family 2 - - - 0.00000000000000000000000000000000000000000000000000000000002636 222.0
PYH3_k127_6213762_7 PFAM glycosyl transferase family 2 K07011 - - 0.00000000000000000000000000000000000000000000006323 192.0
PYH3_k127_6213762_8 transferase activity, transferring glycosyl groups - - - 0.000000000000000000000000000000000000000001412 170.0
PYH3_k127_6213762_9 Methyltransferase domain - - - 0.0000000000000000000000000000000000004295 154.0
PYH3_k127_6244157_0 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K01835 - 5.4.2.2 1.659e-273 850.0
PYH3_k127_6244157_1 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001018 341.0
PYH3_k127_6244157_2 Phosphoglycerate mutase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002543 269.0
PYH3_k127_6244157_3 Belongs to the GPI family K01810 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 5.3.1.9 0.000006434 48.0
PYH3_k127_6246236_0 Radical SAM superfamily K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001146 494.0
PYH3_k127_6246236_1 Sodium/calcium exchanger protein K07300 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004365 419.0
PYH3_k127_6246236_10 Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation K06891 GO:0003674,GO:0005488,GO:0005515,GO:0006950,GO:0008150,GO:0009266,GO:0009408,GO:0009628,GO:0050896,GO:0051087 - 0.000000000000000000000000000009143 123.0
PYH3_k127_6246236_11 Regulatory protein, FmdB family - - - 0.0000000000000000000000000005583 115.0
PYH3_k127_6246236_13 Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ K06137 - 1.3.3.11 0.0000000000000000000000000818 108.0
PYH3_k127_6246236_2 Evidence 4 Homologs of previously reported genes of - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001747 374.0
PYH3_k127_6246236_3 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001648 376.0
PYH3_k127_6246236_4 Converts alpha-N-acetylneuranimic acid (Neu5Ac) to the beta-anomer, accelerating the equilibrium between the alpha- and beta-anomers. Probably facilitates sialidase-negative bacteria to compete sucessfully for limited amounts of extracellular Neu5Ac, which is likely taken up in the beta-anomer. In addition, the rapid removal of sialic acid from solution might be advantageous to the bacterium to damp down host responses - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002686 313.0
PYH3_k127_6246236_5 TPM domain K06872 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000034 294.0
PYH3_k127_6246236_8 - K11477 - - 0.0000000000000000000000000000000000000000000000000000009822 197.0
PYH3_k127_6246236_9 Domain of unknown function (DUF5069) - - - 0.000000000000000000000000000000000000000000000006829 175.0
PYH3_k127_6254739_0 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.0 1468.0
PYH3_k127_6254739_1 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 0.0 1100.0
PYH3_k127_6254739_10 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002237 539.0
PYH3_k127_6254739_11 Multicopper oxidase K00368,K22349 - 1.16.3.3,1.7.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002668 535.0
PYH3_k127_6254739_12 Glycyl-tRNA synthetase alpha subunit K01878 - 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007991 529.0
PYH3_k127_6254739_13 transmembrane transporter activity K03535 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003366 532.0
PYH3_k127_6254739_14 Memo-like protein K06990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006698 543.0
PYH3_k127_6254739_15 Cysteine-rich domain K00241,K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006156 478.0
PYH3_k127_6254739_16 protein conserved in bacteria K09859 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007969 480.0
PYH3_k127_6254739_17 B-1 B cell differentiation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002494 476.0
PYH3_k127_6254739_18 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006173 446.0
PYH3_k127_6254739_19 Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family K00240 - 1.3.5.1,1.3.5.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 432.0
PYH3_k127_6254739_2 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 6.234e-311 961.0
PYH3_k127_6254739_20 Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate K11752 - 1.1.1.193,3.5.4.26 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004767 408.0
PYH3_k127_6254739_21 LPP20 lipoprotein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005859 399.0
PYH3_k127_6254739_22 amino acid transport - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008258 392.0
PYH3_k127_6254739_23 - K02450 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 360.0
PYH3_k127_6254739_24 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 362.0
PYH3_k127_6254739_25 response to heat K07090 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 355.0
PYH3_k127_6254739_26 Lumazine binding domain K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001972 316.0
PYH3_k127_6254739_27 Peptidoglycan-synthase activator LpoB K07337 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000186 310.0
PYH3_k127_6254739_28 helix_turn_helix, cAMP Regulatory protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002695 285.0
PYH3_k127_6254739_29 PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides K03767,K03768 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000007538 274.0
PYH3_k127_6254739_3 Protein involved in outer membrane biogenesis K07290 - - 4.847e-271 871.0
PYH3_k127_6254739_30 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002583 261.0
PYH3_k127_6254739_32 Evidence 5 No homology to any previously reported sequences - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002492 248.0
PYH3_k127_6254739_33 2 iron, 2 sulfur cluster binding K13643 - - 0.000000000000000000000000000000000000000000000000000000000001405 212.0
PYH3_k127_6254739_34 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218,K03437,K03501 - 2.1.1.170,2.1.1.185 0.000000000000000000000000000000000000000000000000000000000009767 216.0
PYH3_k127_6254739_35 Cupin 2, conserved barrel domain protein - - - 0.00000000000000000000000000000000000000000000000000000336 193.0
PYH3_k127_6254739_36 HD domain - - - 0.00000000000000000000000000000000000000000000000000003541 196.0
PYH3_k127_6254739_38 Toxic component of a toxin-antitoxin (TA) module. An RNase K07064 - - 0.00000000000000000000000000000000000000000000000004377 181.0
PYH3_k127_6254739_39 sequence-specific DNA binding - - - 0.0000000000000000000000000000000000000000000003376 172.0
PYH3_k127_6254739_4 tRNA-splicing ligase RtcB K14415 - 6.5.1.3 3.966e-260 807.0
PYH3_k127_6254739_41 PFAM Archease protein family (DUF101 UPF0211) - - - 0.0000000000000000000000000000005687 133.0
PYH3_k127_6254739_43 - - - - 0.000000000000000000000000001151 113.0
PYH3_k127_6254739_45 - - - - 0.00000000000249 72.0
PYH3_k127_6254739_5 pyruvate decarboxylase activity K04103 - 4.1.1.74 3.323e-259 809.0
PYH3_k127_6254739_6 Glycyl-tRNA synthetase beta subunit K01879 - 6.1.1.14 1.784e-246 783.0
PYH3_k127_6254739_7 Metallopeptidase family M24 K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002768 604.0
PYH3_k127_6254739_8 MFS_1 like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002242 584.0
PYH3_k127_6254739_9 Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate K00147 GO:0003674,GO:0003824,GO:0004350,GO:0008150,GO:0008152,GO:0016491,GO:0016620,GO:0016903,GO:0055114 1.2.1.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005919 568.0
PYH3_k127_6259486_0 Leucyl-tRNA synthetase, Domain 2 K01869 - 6.1.1.4 0.0 1453.0
PYH3_k127_6259486_1 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1363.0
PYH3_k127_6259486_10 phosphonoacetaldehyde hydrolase activity K20881 - 3.1.3.5 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003983 284.0
PYH3_k127_6259486_11 DNA polymerase III, delta subunit K02340 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000139 275.0
PYH3_k127_6259486_12 Belongs to the sigma-70 factor family. ECF subfamily K03088 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001547 259.0
PYH3_k127_6259486_13 Methyltransferase domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005961 252.0
PYH3_k127_6259486_14 PFAM Formylglycine-generating sulfatase enzyme - - - 0.0000000000000000000000000000000000000000000000000000000000000009563 230.0
PYH3_k127_6259486_15 - - - - 0.000000000000000000000000000000000000000000000000000000000000003834 220.0
PYH3_k127_6259486_17 Belongs to the Fur family K09825 - - 0.000000000000000000000008699 106.0
PYH3_k127_6259486_18 Binds directly to 16S ribosomal RNA K02968 - - 0.000000000000000000001521 97.0
PYH3_k127_6259486_2 succinyl-diaminopimelate desuccinylase activity - - - 3.467e-222 696.0
PYH3_k127_6259486_20 AntiSigma factor - - - 0.0000000000001701 75.0
PYH3_k127_6259486_22 PFAM Blue (type 1) copper domain - - - 0.00003146 52.0
PYH3_k127_6259486_3 GTPase that plays an essential role in the late steps of ribosome biogenesis K03977 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001255 609.0
PYH3_k127_6259486_5 Di-haem cytochrome c peroxidase K00428 - 1.11.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001677 493.0
PYH3_k127_6259486_6 Evidence 2b Function of strongly homologous gene K18139 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001092 461.0
PYH3_k127_6259486_7 glutathione-regulated potassium exporter activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007448 400.0
PYH3_k127_6259486_8 Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) K01591 - 4.1.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003877 337.0
PYH3_k127_6259486_9 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 333.0
PYH3_k127_6424293_0 DNA-directed DNA polymerase K02337 - 2.7.7.7 0.0 1850.0
PYH3_k127_6424293_1 Carbamoyl-phosphate synthetase large chain, oligomerisation domain K01955 - 6.3.5.5 0.0 1688.0
PYH3_k127_6424293_10 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00812 - 2.6.1.1 1.062e-195 619.0
PYH3_k127_6424293_11 serine-type endopeptidase activity K04771 - 3.4.21.107 1.149e-195 619.0
PYH3_k127_6424293_12 Phosphoribosylglycinamide synthetase, C domain K01945 - 6.3.4.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002206 606.0
PYH3_k127_6424293_13 Carbamoyl-phosphate synthase small chain, CPSase domain K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009714 575.0
PYH3_k127_6424293_14 Phosphomethylpyrimidine kinase K03272 - 2.7.1.167,2.7.7.70 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001626 515.0
PYH3_k127_6424293_15 Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain K00609 - 2.1.3.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006303 512.0
PYH3_k127_6424293_16 Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA K01962 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008737 491.0
PYH3_k127_6424293_17 Belongs to the SIS family. GutQ KpsF subfamily K06041 - 5.3.1.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005597 447.0
PYH3_k127_6424293_18 Peptidase family S49 K04773 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001382 421.0
PYH3_k127_6424293_19 chaperone-mediated protein folding - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001244 413.0
PYH3_k127_6424293_2 FAD linked oxidases, C-terminal domain K00104 - 1.1.3.15 0.0 1360.0
PYH3_k127_6424293_20 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000249 398.0
PYH3_k127_6424293_21 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves K05896 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003614 339.0
PYH3_k127_6424293_22 RadC-like JAB domain K03630 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004965 328.0
PYH3_k127_6424293_23 Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria K00979 - 2.7.7.38 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000235 301.0
PYH3_k127_6424293_24 Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant K02825 - 2.4.2.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002083 280.0
PYH3_k127_6424293_25 Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves K06024 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000004702 270.0
PYH3_k127_6424293_26 Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides K03624 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001557 253.0
PYH3_k127_6424293_27 protein homooligomerization - - - 0.00000000000000000000000000000000000000000000000000000000000000000000002191 253.0
PYH3_k127_6424293_28 Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate K00954 - 2.7.7.3 0.0000000000000000000000000000000000000000000000000000000000000000005553 233.0
PYH3_k127_6424293_29 CDP-alcohol phosphatidyltransferase K00995 - 2.7.8.5 0.00000000000000000000000000000000000000000000000000000000000000000664 231.0
PYH3_k127_6424293_3 Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner K03596 - - 6.91e-321 990.0
PYH3_k127_6424293_30 Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP K08591 - 2.3.1.15 0.000000000000000000000000000000000000000000000000000000000005761 219.0
PYH3_k127_6424293_31 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.000000000000000000000000000000000000000000000000000000005362 213.0
PYH3_k127_6424293_32 ribonucleoside-diphosphate reductase activity K07735 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000005998 201.0
PYH3_k127_6424293_33 Telomere recombination K07566 - 2.7.7.87 0.000000000000000000000000000000000000000000000000002969 190.0
PYH3_k127_6424293_34 Conserved hypothetical protein 95 - - - 0.00000000000000000000000000000000000000000000000006165 184.0
PYH3_k127_6424293_36 domain protein K10716 - - 0.000000000000000000000000000000000005386 146.0
PYH3_k127_6424293_37 - - - - 0.000000000000000000000000008898 110.0
PYH3_k127_6424293_38 Putative regulatory protein - - - 0.00000000000000000000000009205 111.0
PYH3_k127_6424293_4 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 1.175e-310 959.0
PYH3_k127_6424293_42 - - - - 0.0000000000001454 85.0
PYH3_k127_6424293_44 - - - - 0.00001155 48.0
PYH3_k127_6424293_5 AICARFT/IMPCHase bienzyme K00602 - 2.1.2.3,3.5.4.10 2.088e-297 916.0
PYH3_k127_6424293_6 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01465 - 3.5.2.3 9.062e-229 713.0
PYH3_k127_6424293_7 glucan 1,4-alpha-glucosidase activity - - - 3.494e-228 724.0
PYH3_k127_6424293_8 Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor K00833 - 2.6.1.62 3.188e-223 699.0
PYH3_k127_6424293_9 elongation factor Tu domain 2 protein K02355 - - 3.666e-210 674.0
PYH3_k127_6435469_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0 1191.0
PYH3_k127_6435469_1 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 7.119e-255 792.0
PYH3_k127_6435469_10 Periplasmic binding protein K02016 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001221 353.0
PYH3_k127_6435469_11 Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily K02015 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005908 327.0
PYH3_k127_6435469_12 ABC transporter K02013 - 3.6.3.34 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002846 315.0
PYH3_k127_6435469_13 Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000003833 291.0
PYH3_k127_6435469_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008392 289.0
PYH3_k127_6435469_15 cob(I)yrinic acid a,c-diamide adenosyltransferase activity K00798,K13821 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005525,GO:0006725,GO:0006766,GO:0006767,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009235,GO:0009236,GO:0009987,GO:0016043,GO:0016740,GO:0016765,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019003,GO:0019438,GO:0019538,GO:0022607,GO:0030091,GO:0030554,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032559,GO:0032561,GO:0033013,GO:0033014,GO:0034641,GO:0035639,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043170,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0051186,GO:0051188,GO:0051259,GO:0051260,GO:0065003,GO:0070206,GO:0070207,GO:0071704,GO:0071840,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.2.1.88,1.5.5.2,2.5.1.17 0.000000000000000000000000000000000000000000000000000000000000000000000000000002545 269.0
PYH3_k127_6435469_16 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000006704 254.0
PYH3_k127_6435469_17 cheY-homologous receiver domain K02658 - - 0.0000000000000000000000000000000000000000000000000000000000000004092 221.0
PYH3_k127_6435469_18 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000001664 223.0
PYH3_k127_6435469_19 Two component signalling adaptor domain K02487,K06596 - - 0.00000000000000000000000000000000000000000000000000006939 200.0
PYH3_k127_6435469_2 Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily K01756 - 4.3.2.2 2.561e-219 688.0
PYH3_k127_6435469_20 methyltransferase activity K21377 - 2.1.1.302 0.000000000000000000000000000000000000000000000000001526 196.0
PYH3_k127_6435469_21 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000000000000000000000589 187.0
PYH3_k127_6435469_22 Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons K03625 - - 0.0000000000000000000000000000000000000000000000128 175.0
PYH3_k127_6435469_24 chemotaxis K03408,K03415 - - 0.00000000000000000000000000000000000000003873 157.0
PYH3_k127_6435469_25 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01923,K01952 - 6.3.2.6,6.3.5.3 0.0000000000000000000000000000009296 123.0
PYH3_k127_6435469_27 MFS/sugar transport protein K02575 - - 0.00000000000000000000004192 102.0
PYH3_k127_6435469_29 protein conserved in bacteria - - - 0.0000000002838 66.0
PYH3_k127_6435469_3 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K14652 - 3.5.4.25,4.1.99.12 3.035e-218 681.0
PYH3_k127_6435469_4 Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). K02660 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000174 597.0
PYH3_k127_6435469_5 photosynthesis K02453,K02660 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008153 419.0
PYH3_k127_6435469_6 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001363 389.0
PYH3_k127_6435469_7 TonB dependent receptor K02014 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 410.0
PYH3_k127_6435469_8 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005424 388.0
PYH3_k127_6435469_9 SAICAR synthetase K01923 GO:0003674,GO:0003824,GO:0004639,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006188,GO:0006189,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.2.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004641 372.0
PYH3_k127_6445620_0 Ami_3 K01448 - 3.5.1.28 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002261 394.0
PYH3_k127_6445620_1 TatD related DNase K03424 - - 0.00000000000000000000000000000000000000000000000001215 182.0
PYH3_k127_6445620_2 Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs K06173 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016853,GO:0016866,GO:0031119,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.12 0.0000000000000000000000000000000000000001718 154.0
PYH3_k127_6521094_0 stress-induced mitochondrial fusion - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000101 414.0
PYH3_k127_6521094_2 Cytochrome c - - - 0.0000000000000000000000000000000000000000235 156.0
PYH3_k127_6544049_0 Multicopper oxidase K00368,K07233,K22349 - 1.16.3.3,1.7.2.1 0.0 2836.0
PYH3_k127_6544049_1 amino acid - - - 3.826e-290 900.0
PYH3_k127_6544049_11 PFAM Uncharacterised ACR, COG1259 K08999 - - 0.0000000000001373 71.0
PYH3_k127_6544049_2 rRNA (guanine-N2-)-methyltransferase activity K09846,K13604,K21460 GO:0003674,GO:0003824,GO:0006725,GO:0006778,GO:0006779,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0009058,GO:0009987,GO:0015994,GO:0015995,GO:0016740,GO:0016741,GO:0018130,GO:0019438,GO:0030493,GO:0030494,GO:0032259,GO:0033013,GO:0033014,GO:0034641,GO:0036067,GO:0036069,GO:0042440,GO:0044237,GO:0044249,GO:0044271,GO:0046148,GO:0046483,GO:0051186,GO:0051188,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.1.210,2.1.1.304,2.1.1.333 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002145 505.0
PYH3_k127_6544049_4 metallopeptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001412 413.0
PYH3_k127_6544049_5 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 399.0
PYH3_k127_6544049_6 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006514 374.0
PYH3_k127_6544049_7 PFAM blue (type 1) copper domain protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005285 359.0
PYH3_k127_6544049_8 membrane K08976 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001583 345.0
PYH3_k127_6564140_0 aerobic electron transport chain K00425,K08738 - 1.10.3.14 9.934e-281 877.0
PYH3_k127_6584518_0 ABC transporter K06158 - - 2.021e-294 913.0
PYH3_k127_6584518_1 radical SAM domain protein - - - 3.529e-292 913.0
PYH3_k127_6584518_10 deoxyhypusine monooxygenase activity K08884 - 2.7.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008968 535.0
PYH3_k127_6584518_11 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000411 503.0
PYH3_k127_6584518_12 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006082,GO:0006732,GO:0006766,GO:0006767,GO:0006768,GO:0006790,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008710,GO:0009058,GO:0009102,GO:0009108,GO:0009110,GO:0009987,GO:0016020,GO:0016053,GO:0016740,GO:0016746,GO:0016747,GO:0017144,GO:0018130,GO:0019752,GO:0019842,GO:0030170,GO:0030312,GO:0032787,GO:0034641,GO:0036094,GO:0042364,GO:0043167,GO:0043168,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044464,GO:0046394,GO:0046483,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0070279,GO:0071704,GO:0071944,GO:0072330,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.3.1.29,2.3.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007268 489.0
PYH3_k127_6584518_13 Belongs to the methyltransferase superfamily K07444 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002147 484.0
PYH3_k127_6584518_14 -O-antigen K02847,K13009,K16705 GO:0003674,GO:0003824,GO:0006464,GO:0006486,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016740,GO:0016757,GO:0019538,GO:0034645,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0070085,GO:0071704,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003954 500.0
PYH3_k127_6584518_15 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006646 463.0
PYH3_k127_6584518_16 MgsA AAA+ ATPase C terminal K07478 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005732 461.0
PYH3_k127_6584518_17 Histidyl-tRNA synthetase K02502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001926 450.0
PYH3_k127_6584518_18 Lysin motif K08307 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002909 421.0
PYH3_k127_6584518_19 C-terminal domain of 1-Cys peroxiredoxin K03386 - 1.11.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007087 369.0
PYH3_k127_6584518_2 Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family K00058 - 1.1.1.399,1.1.1.95 3.37e-280 867.0
PYH3_k127_6584518_20 Evidence 4 Homologs of previously reported genes of - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009917 353.0
PYH3_k127_6584518_21 ATPases associated with a variety of cellular activities K01990,K09689,K09691 - 3.6.3.38 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007479 328.0
PYH3_k127_6584518_22 GTP cyclohydrolase I K01495 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003933,GO:0003934,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006066,GO:0006725,GO:0006729,GO:0006732,GO:0006807,GO:0008150,GO:0008152,GO:0008270,GO:0009058,GO:0009108,GO:0009987,GO:0016787,GO:0016810,GO:0016814,GO:0017076,GO:0017144,GO:0018130,GO:0019001,GO:0019238,GO:0019438,GO:0019751,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034311,GO:0034312,GO:0034641,GO:0035639,GO:0036094,GO:0042558,GO:0042559,GO:0043167,GO:0043168,GO:0043169,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046146,GO:0046165,GO:0046173,GO:0046483,GO:0046872,GO:0046914,GO:0051186,GO:0051188,GO:0071704,GO:0097159,GO:0097367,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1901615,GO:1901617 3.5.4.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005076 319.0
PYH3_k127_6584518_23 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004761 316.0
PYH3_k127_6584518_24 Diphthamide synthase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000006474 297.0
PYH3_k127_6584518_25 hydrolase activity, acting on ester bonds - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001973 297.0
PYH3_k127_6584518_26 peptidyl-tyrosine sulfation - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000001052 286.0
PYH3_k127_6584518_27 cell envelope organization K05807,K08309 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001384 265.0
PYH3_k127_6584518_28 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000001863 245.0
PYH3_k127_6584518_29 Bacterial membrane protein YfhO - - - 0.00000000000000000000000000000000000000000000000000000000000000002041 251.0
PYH3_k127_6584518_3 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 GO:0003674,GO:0003824,GO:0004019,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006163,GO:0006164,GO:0006167,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0017144,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044208,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046033,GO:0046040,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.4.4 2.4e-221 693.0
PYH3_k127_6584518_30 SelR domain K07305 - 1.8.4.12 0.0000000000000000000000000000000000000000000000000000000000002427 214.0
PYH3_k127_6584518_31 Peptidyl-prolyl cis-trans isomerase K01802,K03772 - 5.2.1.8 0.0000000000000000000000000000000000000000000000000000005886 194.0
PYH3_k127_6584518_32 Domain of unknown function (DUF5069) - - - 0.0000000000000000000000000000000000000000000000000001828 190.0
PYH3_k127_6584518_33 Ferredoxin K04755 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006091,GO:0006790,GO:0008150,GO:0008152,GO:0009055,GO:0009987,GO:0016043,GO:0016226,GO:0016491,GO:0022607,GO:0022900,GO:0031163,GO:0044085,GO:0044237,GO:0044424,GO:0044444,GO:0044464,GO:0048037,GO:0051186,GO:0051536,GO:0051537,GO:0051540,GO:0055114,GO:0071840 - 0.00000000000000000000000000000000000000000000000005125 180.0
PYH3_k127_6584518_34 synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000000000006767 194.0
PYH3_k127_6584518_35 macromolecule localization K01992,K09690 - - 0.000000000000000000000000000000000000000000000009779 181.0
PYH3_k127_6584518_36 Cytochrome c K00405 - - 0.0000000000000000000000000000000000000000000001107 172.0
PYH3_k127_6584518_37 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.00000000000000000000000000000009304 132.0
PYH3_k127_6584518_38 Prokaryotic N-terminal methylation motif K02650 GO:0005575,GO:0005623,GO:0009289,GO:0042995,GO:0044464 - 0.0000000000000000000000000000731 122.0
PYH3_k127_6584518_4 Tetratricopeptide repeat - - - 5.755e-214 681.0
PYH3_k127_6584518_40 protein maturation K07390,K13628,K15724 - - 0.00000000000000009479 83.0
PYH3_k127_6584518_41 DoxX-like family - - - 0.0000000000000003361 83.0
PYH3_k127_6584518_42 PFAM Glycosyl transferase, group 1 - - - 0.000001148 60.0
PYH3_k127_6584518_44 - - - - 0.0001496 44.0
PYH3_k127_6584518_5 Evidence 2b Function of strongly homologous gene - - - 6.299e-210 656.0
PYH3_k127_6584518_6 Participates in initiation and elongation during chromosome replication K02314 - 3.6.4.12 5.148e-206 667.0
PYH3_k127_6584518_7 Type II/IV secretion system protein K02669 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002235 595.0
PYH3_k127_6584518_8 twitching motility protein K02670 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006211 538.0
PYH3_k127_6584518_9 UDP binding domain K13015 - 1.1.1.136 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001149 527.0
PYH3_k127_6618825_0 Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate K03639 - 4.1.99.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007525 518.0
PYH3_k127_6618825_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008602 474.0
PYH3_k127_6618825_10 diguanylate cyclase - - - 0.00000000000000000001604 102.0
PYH3_k127_6618825_2 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA K01963 - 2.1.3.15,6.4.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001012 465.0
PYH3_k127_6618825_3 PHP domain protein K01624,K07053 - 3.1.3.97,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 400.0
PYH3_k127_6618825_4 Beta-lactamase superfamily domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001536 329.0
PYH3_k127_6618825_5 tRNA (guanine(37)-N(1))-methyltransferase activity K01091,K01633,K15429 - 1.13.11.81,2.1.1.228,3.1.3.18,4.1.2.25,5.1.99.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000377 306.0
PYH3_k127_6618825_6 Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP) K03637 - 4.6.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000006731 258.0
PYH3_k127_6618825_7 Belongs to the NiCoT transporter (TC 2.A.52) family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000184 257.0
PYH3_k127_6618825_8 MoaE protein K03635 - 2.8.1.12 0.00000000000000000000000000000000000000000000000000000000000000000008964 244.0
PYH3_k127_6618825_9 Mo-molybdopterin cofactor metabolic process K03636 - - 0.00000000000000000000004484 112.0
PYH3_k127_6658890_0 Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type K01889 - 6.1.1.20 6.411e-254 791.0
PYH3_k127_6658890_1 B3/4 domain K01890 - 6.1.1.20 7.618e-247 774.0
PYH3_k127_6658890_10 - - - - 0.00000004551 55.0
PYH3_k127_6658890_2 16S rRNA methyltransferase RsmB/F K03500 - 2.1.1.176 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000381 512.0
PYH3_k127_6658890_3 Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus K00604 GO:0003674,GO:0003824,GO:0004479,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006413,GO:0006464,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016741,GO:0016742,GO:0019538,GO:0019988,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036211,GO:0043043,GO:0043170,GO:0043412,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0046483,GO:0071704,GO:0071951,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 2.1.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002654 454.0
PYH3_k127_6658890_4 pectinesterase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008722 407.0
PYH3_k127_6658890_5 Ribulose-phosphate 3 epimerase family K01783 - 5.1.3.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007452 351.0
PYH3_k127_6658890_6 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000001492 252.0
PYH3_k127_6658890_8 IMP dehydrogenase activity K07182 - - 0.00000000000000000000005019 104.0
PYH3_k127_6784347_0 Thiamine pyrophosphate enzyme, N-terminal TPP binding domain K01652 - 2.2.1.6 0.0 1044.0
PYH3_k127_6784347_1 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 1.619e-260 809.0
PYH3_k127_6784347_10 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 - 4.1.1.65 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000002046 279.0
PYH3_k127_6784347_11 C4-type zinc ribbon domain K07164 - - 0.0000000000000000000000000000000000000000000000000000000000000000000001007 247.0
PYH3_k127_6784347_12 Protein of Unknown function (DUF2784) - - - 0.000000000000000000000000000000000000000007365 157.0
PYH3_k127_6784347_13 Stage II sporulation protein K06381 - - 0.000000000000000000000000000000000008132 145.0
PYH3_k127_6784347_14 RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication K02316 - - 0.00000000000000000000000000000005764 130.0
PYH3_k127_6784347_15 Cupin 2, conserved barrel domain protein - - - 0.000000000000000000000000000004234 124.0
PYH3_k127_6784347_16 Protein of unknown function (DUF2905) - - - 0.00000000000001117 76.0
PYH3_k127_6784347_18 - - - - 0.00000009989 53.0
PYH3_k127_6784347_2 Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate K00053 - 1.1.1.86 5.127e-198 620.0
PYH3_k127_6784347_3 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth K03086 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001151 578.0
PYH3_k127_6784347_4 Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate K00133 - 1.2.1.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000654 546.0
PYH3_k127_6784347_5 NHL repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008076 463.0
PYH3_k127_6784347_6 Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate K00052 - 1.1.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002004 451.0
PYH3_k127_6784347_7 RNA-DNA hybrid ribonuclease activity K03471 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001395 323.0
PYH3_k127_6784347_8 ACT domain K01653 - 2.2.1.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003631 299.0
PYH3_k127_6784347_9 CDP-alcohol phosphatidyltransferase K17103 - 2.7.8.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005087 303.0
PYH3_k127_6955406_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 3.517e-215 683.0
PYH3_k127_6955406_2 PFAM beta-lactamase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004661 345.0
PYH3_k127_6955406_3 Uncharacterised protein family UPF0047 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000105 263.0
PYH3_k127_6955406_4 Memo-like protein K06990 - - 0.000000000000000000000000000000000000000000645 162.0
PYH3_k127_7044712_0 PFAM Formylglycine-generating sulfatase enzyme K20333 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003197 387.0
PYH3_k127_7044712_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000002482 282.0
PYH3_k127_7044712_2 Uncharacterized protein conserved in bacteria (DUF2062) - - - 0.0000000000000000000000000000000000000002733 157.0
PYH3_k127_7383385_0 Formiminotransferase domain K00603,K01746,K13990 - 2.1.2.5,4.3.1.4 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001156 380.0
PYH3_k127_7383385_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K01142,K10773 GO:0000702,GO:0000703,GO:0003674,GO:0003824,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006285,GO:0006289,GO:0006296,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033683,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0140097,GO:1901360 3.1.11.2,4.2.99.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003285 344.0
PYH3_k127_7383385_2 Belongs to the sulfur carrier protein TusA family K04085 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000002573 279.0
PYH3_k127_7383385_3 Belongs to the sulfur carrier protein TusA family - - - 0.00000000000000000000000000000000000000000000000000000000005376 207.0
PYH3_k127_7383385_4 Sulfurtransferase TusA - - - 0.0000000000000000000000000000000000000002443 150.0
PYH3_k127_7383385_5 Belongs to the bacterial ribosomal protein bS21 family K02970 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000003385 108.0
PYH3_k127_7388695_0 - - - - 0.000000000000000000000000000000000000000000000000000000000001827 223.0
PYH3_k127_7416704_0 involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane K04744 - - 3.223e-309 967.0
PYH3_k127_7416704_1 PhoQ Sensor - - - 2.178e-271 865.0
PYH3_k127_7416704_10 Thioredoxin-like domain K03671 - - 0.0000000000000000000000000000000000000000000000000000002565 196.0
PYH3_k127_7416704_11 Shikimate quinate 5-dehydrogenase - - - 0.000000000000000000000000000000000000000000000000000002845 211.0
PYH3_k127_7416704_12 phosphorelay sensor kinase activity K02038,K02282,K07018,K07315 - 3.1.3.3 0.00000000000000000000000000000000000000000000000005855 194.0
PYH3_k127_7416704_14 peptidyl-tyrosine sulfation - - - 0.00000000000000000000000000001262 123.0
PYH3_k127_7416704_15 Protein of unknown function (DUF507) - - - 0.0000000000000000000000008789 107.0
PYH3_k127_7416704_16 Protein of unknown function (DUF507) - - - 0.0000000000000000000004678 102.0
PYH3_k127_7416704_18 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000002525 49.0
PYH3_k127_7416704_2 Bacterial regulatory protein, Fis family K02481,K07713,K07714 - - 1.752e-210 665.0
PYH3_k127_7416704_3 May be involved in recombinational repair of damaged DNA K03631 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003026 551.0
PYH3_k127_7416704_6 RNase_H superfamily K07502 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001002 308.0
PYH3_k127_7416704_7 response regulator K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005556 305.0
PYH3_k127_7416704_8 AhpC/TSA family K03564 - 1.11.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000004985 241.0
PYH3_k127_7416704_9 Cyclophilin-like K09143 - - 0.000000000000000000000000000000000000000000000000000000001299 202.0
PYH3_k127_7450440_0 Belongs to the argininosuccinate synthase family. Type 1 subfamily K01940 - 6.3.4.5 1.191e-230 717.0
PYH3_k127_7450440_1 Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine K01586 - 4.1.1.20 8.067e-211 661.0
PYH3_k127_7450440_10 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000311 377.0
PYH3_k127_7450440_11 deaminated base DNA N-glycosylase activity K21929 GO:0003674,GO:0003824,GO:0004844,GO:0005488,GO:0006139,GO:0006259,GO:0006281,GO:0006284,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016787,GO:0016798,GO:0016799,GO:0019104,GO:0033554,GO:0033958,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0048037,GO:0050896,GO:0051536,GO:0051539,GO:0051540,GO:0051716,GO:0071704,GO:0090304,GO:0097506,GO:0140097,GO:1901360 3.2.2.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008212 348.0
PYH3_k127_7450440_12 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K01834 - 5.4.2.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001689 333.0
PYH3_k127_7450440_13 Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan K01778 - 5.1.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002878 294.0
PYH3_k127_7450440_14 cell adhesion K02650 - - 0.00000000000000000000000000000000000000000000000000000000000000000003093 237.0
PYH3_k127_7450440_15 Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate K00891 GO:0000287,GO:0003674,GO:0003824,GO:0004765,GO:0005488,GO:0006082,GO:0006520,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009072,GO:0009073,GO:0009987,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019438,GO:0019632,GO:0019752,GO:0032787,GO:0043167,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046872,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901615 2.7.1.71 0.000000000000000000000000000000000000000000000000000000000000000008619 238.0
PYH3_k127_7450440_17 transmembrane signaling receptor activity - - - 0.0000000000000000000000000000002461 130.0
PYH3_k127_7450440_19 monooxygenase activity K00688,K15760,K16157,K16242,K18223,K22353,K22357 GO:0003674,GO:0003824,GO:0004497,GO:0005575,GO:0008150,GO:0008152,GO:0009987,GO:0015049,GO:0015050,GO:0015947,GO:0016491,GO:0016705,GO:0016709,GO:0032991,GO:0043446,GO:0044237,GO:0055114,GO:0071704,GO:1902494 1.14.13.227,1.14.13.236,1.14.13.25,1.14.13.69,2.4.1.1 0.0000000000000000000002405 99.0
PYH3_k127_7450440_2 Aminotransferase class-III K00821 - 2.6.1.11,2.6.1.17 9.125e-200 629.0
PYH3_k127_7450440_3 Argininosuccinate lyase C-terminal K01755 - 4.3.2.1 4.056e-199 629.0
PYH3_k127_7450440_4 Lysin motif - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 494.0
PYH3_k127_7450440_5 MOFRL family K11529 - 2.7.1.165 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008355 467.0
PYH3_k127_7450440_6 Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) K01714 - 4.3.3.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002943 456.0
PYH3_k127_7450440_7 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005461 446.0
PYH3_k127_7450440_8 Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate K00215 - 1.17.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008503 415.0
PYH3_k127_7450440_9 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006745 396.0
PYH3_k127_7470937_0 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology - - - 6.312e-215 698.0
PYH3_k127_7470937_1 peptidyl-lysine modification to peptidyl-hypusine K00809 - 2.5.1.46 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000579 587.0
PYH3_k127_7470937_2 metal-dependent phosphohydrolase, HD sub domain K07814 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009221 349.0
PYH3_k127_7470937_3 Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process - - - 0.00000000000000000000000000000000000000000000000000000000000000000002469 241.0
PYH3_k127_7470937_4 Diguanylate cyclase - - - 0.00000000000000000000000000000000000000000000000000000000000002014 230.0
PYH3_k127_7470937_5 general secretion pathway protein K02456,K02650,K02679,K08084 - - 0.0000000000000000000000000000000002029 143.0
PYH3_k127_7470937_9 Aldehyde dehydrogenase family - - - 0.000000001036 63.0
PYH3_k127_7492629_0 Domain of unknown function (DUF4105) - - - 2.978e-251 791.0
PYH3_k127_7492629_1 thiolester hydrolase activity K06889 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001429 371.0
PYH3_k127_7492629_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003014 345.0
PYH3_k127_7492629_3 Lipoprotein K04754 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006004 305.0
PYH3_k127_7492629_4 Protein of unknown function (DUF3015) - - - 0.00000000000000000000000000000000000000000000000764 176.0
PYH3_k127_7492629_5 Protein of unknown function (DUF3015) - - - 0.000000000000000000000000000000000000008864 154.0
PYH3_k127_7492629_6 Domain of unknown function (DUF4384) - - - 0.00000000000000000000000000000000002943 143.0
PYH3_k127_7492629_7 Putative nucleotidyltransferase substrate binding domain - - - 0.0007787 50.0
PYH3_k127_7522085_0 Hydrophobe amphiphile Efflux-1 (HAE1) family K03296,K18138 - - 0.0 1114.0
PYH3_k127_7522085_1 Biotin-lipoyl like K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005037 400.0
PYH3_k127_7522085_10 Domain of unknown function (DUF4410) - - - 0.000000000000002607 86.0
PYH3_k127_7522085_11 - - - - 0.0000000000000092 77.0
PYH3_k127_7522085_2 AI-2E family transporter - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003044 343.0
PYH3_k127_7522085_3 Las17-binding protein actin regulator - - - 0.0000000000000000000000000000000000000000000000000000001825 200.0
PYH3_k127_7522085_4 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000000001332 183.0
PYH3_k127_7522085_5 Protein of unknown function (DUF3313) - - - 0.000000000000000000000000000000000000000000002577 173.0
PYH3_k127_7522085_6 - - - - 0.000000000000000000000000000000000000002323 152.0
PYH3_k127_7522085_7 - - - - 0.000000000000000000000000000000000000002862 151.0
PYH3_k127_7522085_8 Glycogen debranching enzyme - - - 0.000000000000000000000000000001235 123.0
PYH3_k127_7522085_9 - - - - 0.00000000000000000000001579 103.0
PYH3_k127_7587762_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 0.0 1220.0
PYH3_k127_7587762_1 Actin K03569 - - 6.108e-196 615.0
PYH3_k127_7587762_10 RDD family - - - 0.00000000000000000000000000000000000000000000000000000000002876 208.0
PYH3_k127_7587762_2 Peptidoglycan polymerase that is essential for cell wall elongation K05837 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003426 558.0
PYH3_k127_7587762_3 TIGRFAM ribonuclease, Rne Rng family K08300,K08301 - 3.1.26.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002649 560.0
PYH3_k127_7587762_4 Penicillin-binding protein, dimerisation domain K05515 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003257 497.0
PYH3_k127_7587762_5 DNA recombination-mediator protein A K04096 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000332 432.0
PYH3_k127_7587762_6 Stage II sporulation protein K06381 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002271 357.0
PYH3_k127_7587762_7 Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) K07568 GO:0002097,GO:0002099,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016853,GO:0018130,GO:0019438,GO:0034404,GO:0034470,GO:0034641,GO:0034654,GO:0034660,GO:0042455,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046116,GO:0046483,GO:0051075,GO:0055086,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.99.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001465 362.0
PYH3_k127_7587762_8 shape-determining protein MreC K03570 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001541 321.0
PYH3_k127_7587762_9 SurA N-terminal domain K03770 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000003639 224.0
PYH3_k127_7600097_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 3.1e-248 773.0
PYH3_k127_7600097_1 Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins K04487 - 2.8.1.7 8.637e-228 712.0
PYH3_k127_7600097_2 2Fe-2S iron-sulfur cluster binding domain K04755 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000001636 260.0
PYH3_k127_7600097_3 A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters K04488 - - 0.000000000000000000000000000000000000000000000000000000000000000001311 229.0
PYH3_k127_7600097_4 Transcriptional regulator - - - 0.000000000000000000000000000000000000000000000000000000000000000002174 230.0
PYH3_k127_7600097_5 Iron-sulphur cluster biosynthesis K13628 - - 0.00000000000000000000000000000000000000000000000000000008383 198.0
PYH3_k127_7694813_0 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 6.902e-228 711.0
PYH3_k127_7694813_1 An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism K03595 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003718 387.0
PYH3_k127_7694813_2 Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) K02434 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.6,6.3.5.7 0.0000000000000000000000000006567 113.0
PYH3_k127_7694813_3 cell cycle K05589 GO:0000003,GO:0000910,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005623,GO:0005886,GO:0007049,GO:0008150,GO:0009987,GO:0016020,GO:0019954,GO:0022402,GO:0022414,GO:0030428,GO:0032153,GO:0032505,GO:0042802,GO:0043093,GO:0044464,GO:0051301,GO:0071944 - 0.00000000000000000002801 94.0
PYH3_k127_7715822_0 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00982,K00990 - 2.7.7.42,2.7.7.59,2.7.7.89 0.0 1185.0
PYH3_k127_7715822_1 Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions K04077 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0016465,GO:0032991,GO:0044183,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0051082,GO:0061077,GO:0101031,GO:1990220 - 4.392e-308 949.0
PYH3_k127_7715822_10 PFAM ABC transporter K02049,K15578,K15579 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001651 366.0
PYH3_k127_7715822_11 Binding-protein-dependent transport system inner membrane component K15577 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 353.0
PYH3_k127_7715822_12 Major Facilitator Superfamily K02575 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006373 283.0
PYH3_k127_7715822_13 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000157 270.0
PYH3_k127_7715822_14 Cytochrome b(N-terminal)/b6/petB K00412,K02635,K02637,K03887,K03891,K15879 GO:0005575,GO:0005622,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0009512,GO:0009579,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0032991,GO:0040007,GO:0044424,GO:0044425,GO:0044436,GO:0044459,GO:0044464,GO:0070069,GO:0071944 - 0.000000000000000000000000000000000000000000000000000000000000000000000000006867 263.0
PYH3_k127_7715822_15 Ammonium Transporter Family K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000001987 230.0
PYH3_k127_7715822_16 Catalyzes the reaction of cyanate with bicarbonate to produce ammonia and carbon dioxide K01725 - 4.2.1.104 0.0000000000000000000000000000000000000000000000000000000000000001915 235.0
PYH3_k127_7715822_17 Nitrogen regulatory protein P-II K04751,K04752 - - 0.000000000000000000000000000000000000000000000000000000001455 201.0
PYH3_k127_7715822_18 Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter K04078 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0006950,GO:0006986,GO:0008150,GO:0009987,GO:0010033,GO:0035966,GO:0042221,GO:0043167,GO:0043169,GO:0046872,GO:0050896,GO:0051082,GO:0051084,GO:0051085,GO:0051087,GO:0061077 - 0.000000000000000000000000000000000000000000001608 166.0
PYH3_k127_7715822_19 GYD domain - - - 0.000000000000000000000000001307 114.0
PYH3_k127_7715822_2 Glutamine synthetase, catalytic domain K01915 - 6.3.1.2 3.089e-284 876.0
PYH3_k127_7715822_20 PFAM Rieske 2Fe-2S K02636 - 1.10.9.1 0.000000000000000000000004638 107.0
PYH3_k127_7715822_3 Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen K00003,K00982,K00990,K06950,K15371 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 1.1.1.3,1.4.1.2,2.7.7.42,2.7.7.59,2.7.7.89 5.641e-270 850.0
PYH3_k127_7715822_4 Ammonium Transporter Family K03320 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002295 611.0
PYH3_k127_7715822_5 [glutamate-ammonia-ligase] adenylyltransferase activity K00982 GO:0000820,GO:0003674,GO:0003824,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006521,GO:0008150,GO:0008882,GO:0010565,GO:0016020,GO:0016740,GO:0016772,GO:0016779,GO:0019222,GO:0030312,GO:0031323,GO:0033238,GO:0040007,GO:0042221,GO:0044424,GO:0044444,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051171,GO:0060359,GO:0062012,GO:0065007,GO:0070566,GO:0071944,GO:0080090,GO:1901698 2.7.7.42,2.7.7.89 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001619 598.0
PYH3_k127_7715822_6 NMT1-like family K02051,K15576 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001076 572.0
PYH3_k127_7715822_7 sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03089 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001858 477.0
PYH3_k127_7715822_8 Seven times multi-haem cytochrome CxxCH - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001559 469.0
PYH3_k127_7715822_9 TIGRFAM Ammonium transporter K03320 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007187 397.0
PYH3_k127_7737993_0 nodulation K00612 - - 1.359e-252 790.0
PYH3_k127_7737993_1 Probable molybdopterin binding domain K03750 - 2.10.1.1 1.862e-233 726.0
PYH3_k127_7737993_10 Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S- adenosylmethionine. Has broad substrate specificity with 6- aminopurine nucleosides as preferred substrates K00772 - 2.4.2.28 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000108 403.0
PYH3_k127_7737993_11 Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) K00791 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0052381,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.5.1.75 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003345 398.0
PYH3_k127_7737993_12 denitrification pathway K02569,K03532,K15876 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006907 368.0
PYH3_k127_7737993_13 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002432 366.0
PYH3_k127_7737993_14 transferase activity, transferring glycosyl groups - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002321 319.0
PYH3_k127_7737993_15 Helix-turn-helix domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000004097 295.0
PYH3_k127_7737993_16 Mo-molybdopterin cofactor metabolic process K03750,K03753,K13818 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0005488,GO:0005525,GO:0017076,GO:0019001,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.10.1.1,2.7.7.77 0.000000000000000000000000000000000000000000000000000000000000000000000000000001398 265.0
PYH3_k127_7737993_17 Cytochrome C oxidase, cbb3-type, subunit III - - - 0.0000000000000000000000000000000000000000000000000000000000000000000011 238.0
PYH3_k127_7737993_18 Outer membrane lipoprotein - - - 0.00000000000000000000000000000000000000000000000000000000000000000004804 245.0
PYH3_k127_7737993_2 Trypsin K04771 - 3.4.21.107 5.973e-220 693.0
PYH3_k127_7737993_20 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000004644 212.0
PYH3_k127_7737993_21 RNA recognition motif - - - 0.0000000000000000000000000000000000000000009233 160.0
PYH3_k127_7737993_22 Transposase K01991,K02557,K07161,K07484 - - 0.000000000000000000000000000000000000000237 153.0
PYH3_k127_7737993_23 RNA recognition motif - - - 0.000000000000003105 77.0
PYH3_k127_7737993_3 This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex K03572 GO:0003674,GO:0003676,GO:0003677,GO:0003697,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006281,GO:0006298,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0032300,GO:0032991,GO:0033554,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990391 - 7.051e-208 663.0
PYH3_k127_7737993_4 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000014 595.0
PYH3_k127_7737993_5 oligosaccharyl transferase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000705 524.0
PYH3_k127_7737993_6 pfkB family carbohydrate kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002059 506.0
PYH3_k127_7737993_7 Evidence 5 No homology to any previously reported sequences K07126 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001725 520.0
PYH3_k127_7737993_8 Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes K03118 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008925 482.0
PYH3_k127_7737993_9 macromolecule localization K01421,K01992,K09690 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002706 409.0
PYH3_k127_7773650_0 COG1249 Pyruvate 2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase (E3) K00322 GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0016020,GO:0030312,GO:0044424,GO:0044444,GO:0044464,GO:0071944 1.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 523.0
PYH3_k127_7773650_1 Phosphomethylpyrimidine kinase K00941 - 2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002985 428.0
PYH3_k127_7773650_10 Histidine kinase K03406 - - 0.00000000000000000000000000000000000000000000000000000000000000000001476 239.0
PYH3_k127_7773650_11 MOSC domain - - - 0.0000000000000000000000000000000000000000000000000000000000000008552 226.0
PYH3_k127_7773650_12 cysteine-type peptidase activity - - - 0.00000000000000000000000000000000000000000000000000000000002687 213.0
PYH3_k127_7773650_15 NMT1-like family K02051,K15598 - - 0.000000000000000000000000000000000000000000000002183 187.0
PYH3_k127_7773650_18 Cytochrome c K00406,K03889 GO:0005575,GO:0005623,GO:0005886,GO:0005887,GO:0008150,GO:0016020,GO:0016021,GO:0031224,GO:0031226,GO:0040007,GO:0044425,GO:0044459,GO:0044464,GO:0071944 - 0.0000000000000000000182 97.0
PYH3_k127_7773650_19 Protein of unknown function (DUF3015) - - - 0.0000000000000003914 83.0
PYH3_k127_7773650_2 Catalyzes the formation of the isocyclic ring in chlorophyll biosynthesis. Mediates the cyclase reaction, which results in the formation of divinylprotochlorophyllide (Pchlide) characteristic of all chlorophylls from magnesium-protoporphyrin IX 13-monomethyl ester (MgPMME) K03594,K07052 - 1.16.3.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004924 368.0
PYH3_k127_7773650_3 Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway K03707 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 3.5.99.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001231 349.0
PYH3_k127_7773650_4 Evidence 4 Homologs of previously reported genes of - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000318 342.0
PYH3_k127_7773650_5 methyltransferase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004871 319.0
PYH3_k127_7773650_6 Ribosomal protein L11 methyltransferase (PrmA) K02687 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000009459 301.0
PYH3_k127_7773650_7 thiolester hydrolase activity K06889,K07397 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000003606 292.0
PYH3_k127_7773650_8 deoxyhypusine monooxygenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000004443 287.0
PYH3_k127_7793560_0 Transglycosylase SLT domain K08309 - - 6.332e-201 649.0
PYH3_k127_7793560_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 609.0
PYH3_k127_7793560_2 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003986 566.0
PYH3_k127_7793560_3 Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs K06941 - 2.1.1.192 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001381 449.0
PYH3_k127_7793560_4 tRNA processing K06864,K09121 - 4.99.1.12 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004172 319.0
PYH3_k127_7793560_5 Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) K02109 - - 0.0000000000000000000000000000000000000000000000000000000000003815 214.0
PYH3_k127_7793560_6 Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division K09888 - - 0.000000000000000000000000001361 115.0
PYH3_k127_7793560_8 Endoribonuclease that initiates mRNA decay K18682 - - 0.00000000006812 68.0
PYH3_k127_7855522_0 Belongs to the mannose-6-phosphate isomerase type 2 family K16011 - 2.7.7.13,5.3.1.8 2.153e-224 702.0
PYH3_k127_7855522_1 Phosphoglucomutase/phosphomannomutase, alpha/beta/alpha domain III K15778 - 5.4.2.2,5.4.2.8 2.008e-200 633.0
PYH3_k127_7855522_10 30S ribosomal protein S23 - - - 0.000000000000000000000001056 106.0
PYH3_k127_7855522_2 DeoC/LacD family aldolase K11645 - 4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000479 532.0
PYH3_k127_7855522_3 D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1 K03841 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005984,GO:0005985,GO:0005986,GO:0005996,GO:0006000,GO:0006002,GO:0006006,GO:0006094,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0009058,GO:0009311,GO:0009312,GO:0009987,GO:0016051,GO:0016311,GO:0016787,GO:0016788,GO:0016791,GO:0019203,GO:0019318,GO:0019319,GO:0019637,GO:0030388,GO:0034637,GO:0042132,GO:0042578,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046351,GO:0046364,GO:0050308,GO:0071704,GO:1901135,GO:1901576 3.1.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000686 386.0
PYH3_k127_7855522_4 smart pdz dhr glgf K04771,K04772 GO:0003674,GO:0003824,GO:0004175,GO:0004252,GO:0005575,GO:0005623,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008236,GO:0016787,GO:0017171,GO:0019538,GO:0030288,GO:0030313,GO:0031975,GO:0042597,GO:0043170,GO:0044238,GO:0044464,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.21.107 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001629 389.0
PYH3_k127_7855522_5 Large family of predicted nucleotide-binding domains - GO:0005575,GO:0005618,GO:0005623,GO:0030312,GO:0044464,GO:0071944 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 332.0
PYH3_k127_7855522_6 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase K00991 - 2.7.7.60 0.000000000000000000000000000000000000000000000000000000000000000000000000000000002953 277.0
PYH3_k127_7855522_7 Protein of unknown function (DUF3108) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000004786 276.0
PYH3_k127_7855522_8 Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) K01770,K12506 - 2.7.7.60,4.6.1.12 0.00000000000000000000000000000000000000000000000000000000000000000217 229.0
PYH3_k127_7855522_9 Serine acetyltransferase, N-terminal K00640 - 2.3.1.30 0.000000000000000000000000000000000000002787 147.0
PYH3_k127_7870745_0 Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties K00688 - 2.4.1.1 0.0 1198.0
PYH3_k127_7870745_1 Belongs to the glycosyl hydrolase 13 family K01214 - 3.2.1.68 1.272e-314 981.0
PYH3_k127_7870745_2 Responsible for synthesis of pseudouridine from uracil K06180 - 5.4.99.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 448.0
PYH3_k127_7870745_3 AAA domain, putative AbiEii toxin, Type IV TA system K09817,K09820 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002078 411.0
PYH3_k127_7870745_4 ABC 3 transport family K09816 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009599 392.0
PYH3_k127_7870745_5 - - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001243 347.0
PYH3_k127_7870745_6 Zinc-uptake complex component A periplasmic K09815,K09818 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000838 336.0
PYH3_k127_7870745_7 Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling K09001 - 2.7.1.170 0.0000000000000000000000000000000000000000000000000000000000000000000000000668 253.0
PYH3_k127_7870745_8 Histidine kinase K03406 - - 0.00000000000000000000000000000000000000000000000000000000009394 210.0
PYH3_k127_7870745_9 acetyltransferase - - - 0.00000000000000000000000000000000000000000000000000000005089 198.0
PYH3_k127_7881601_0 protein secretion by the type I secretion system K02021 - - 2.548e-216 685.0
PYH3_k127_7881601_1 efflux transmembrane transporter activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001328 464.0
PYH3_k127_7881601_2 Belongs to the pseudouridine synthase RsuA family K06178,K06181,K06182 - 5.4.99.20,5.4.99.21,5.4.99.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001121 327.0
PYH3_k127_7881601_3 Histidine kinase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002768 261.0
PYH3_k127_7881601_4 Late embryogenesis abundant protein - - - 0.0000006521 59.0
PYH3_k127_8025499_0 Tfp pilus assembly protein tip-associated adhesin K02674 - - 0.0 1248.0
PYH3_k127_8025499_1 Pilus assembly protein PilX K07140 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007659 386.0
PYH3_k127_8025499_10 protein transport across the cell outer membrane K02457,K02672,K08084,K08085 - - 0.000000000000000000000000822 109.0
PYH3_k127_8025499_11 type IV pilus modification protein PilV K02671,K02681,K10927 - - 0.000000000000000000006852 99.0
PYH3_k127_8025499_12 protein transport across the cell outer membrane - - - 0.000000000005782 73.0
PYH3_k127_8025499_2 Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue K02654 - 3.4.23.43 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 351.0
PYH3_k127_8025499_3 DALR_2 K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005713 341.0
PYH3_k127_8025499_4 Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family K03218 - 2.1.1.185 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006391 316.0
PYH3_k127_8025499_5 pilus assembly protein PilW K02672 - - 0.0000000000000000000000000000000000000000000000000003117 195.0
PYH3_k127_8025499_6 pilus assembly protein PilW K02672 - - 0.00000000000000000000000000000000000003068 160.0
PYH3_k127_8025499_7 Putative Competence protein ComGF K02246,K02248 - - 0.000000000000000000000000000001943 131.0
PYH3_k127_8025499_9 response regulator K03413 - - 0.000000000000000000000000001653 114.0
PYH3_k127_8263640_0 Sugar (and other) transporter K08178 - - 2.04e-213 669.0
PYH3_k127_8263640_1 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255 - 3.4.11.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000767 487.0
PYH3_k127_8263640_2 Glycosyl hydrolase family 3 N terminal domain K01207 - 3.2.1.52 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002214 472.0
PYH3_k127_8263640_3 Vacuole effluxer Atg22 like K06902 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005036 325.0
PYH3_k127_8263640_4 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.000000000000000000000000000000000000000000000000000000000000000000005379 237.0
PYH3_k127_8263640_6 - - - - 0.00000000000000000000000000000000000000000000004596 175.0
PYH3_k127_8282975_0 Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity K07456 - - 1.069e-267 850.0
PYH3_k127_8282975_1 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 9.078e-253 788.0
PYH3_k127_8282975_10 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009754 284.0
PYH3_k127_8282975_11 Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A K00859 - 2.7.1.24 0.0000000000000000000000000000000000000000000000000000000000000001061 228.0
PYH3_k127_8282975_12 Sigma-70, region 4 K03088 - - 0.000000000000000000000000000000000000000000000000002106 188.0
PYH3_k127_8282975_13 Protein of unknown function, DUF547 - - - 0.00000000000000000000000000000000000000000000000001118 190.0
PYH3_k127_8282975_14 phosphorelay signal transduction system - - - 0.00000000000000000000000000000000000000000000000004974 182.0
PYH3_k127_8282975_16 negative regulation of translational initiation K05554,K14670,K15886 - 2.3.1.235 0.00000000000000000000000000000002896 134.0
PYH3_k127_8282975_17 Tellurite resistance protein tehB K05524,K06886 - - 0.00000000000000000001744 100.0
PYH3_k127_8282975_18 RNA recognition motif - - - 0.0000000000000002021 80.0
PYH3_k127_8282975_19 Putative zinc-finger - - - 0.000000002576 62.0
PYH3_k127_8282975_2 tRNA thio-modification K03151 GO:0000049,GO:0002937,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006766,GO:0006767,GO:0006772,GO:0006790,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009228,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0017144,GO:0018130,GO:0019438,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0042364,GO:0042723,GO:0042724,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0072527,GO:0072528,GO:0090304,GO:0097159,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.8.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000205 546.0
PYH3_k127_8282975_22 Protein of unknown function (DUF805) - - - 0.000006181 57.0
PYH3_k127_8282975_3 actin binding - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003295 522.0
PYH3_k127_8282975_4 Pyridine nucleotide-disulphide oxidoreductase K00384 - 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004377 486.0
PYH3_k127_8282975_5 Domain of unknown function (DUF1730) K18979 - 1.17.99.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003369 433.0
PYH3_k127_8282975_6 pectinesterase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002251 402.0
PYH3_k127_8282975_7 Protein of unknown function (DUF3047) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000213 332.0
PYH3_k127_8282975_8 Pfam SNARE associated Golgi protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004048 315.0
PYH3_k127_8282975_9 Histidine kinase K02851 - 2.7.8.33,2.7.8.35 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006749 282.0
PYH3_k127_8333491_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 6.9e-267 830.0
PYH3_k127_8333491_1 ACT domain K00928 - 2.7.2.4 9.473e-214 668.0
PYH3_k127_8333491_2 Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates K03787 - 3.1.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003984 366.0
PYH3_k127_8333491_3 helix_turn_helix, mercury resistance - - - 0.00000000000000000000000000000000000000000000005811 171.0
PYH3_k127_8333491_4 bacterial (prokaryotic) histone like domain K04764 - - 0.0000000000000000000000000000000000000000001166 160.0
PYH3_k127_8333491_5 Proposed homoserine kinase K15635 - 5.4.2.12 0.0000006494 56.0
PYH3_k127_862432_0 Putative modulator of DNA gyrase K03568 - - 1.538e-250 779.0
PYH3_k127_862432_1 Putative modulator of DNA gyrase K03592 - - 6.042e-202 637.0
PYH3_k127_862432_10 Uracil DNA glycosylase superfamily K21929 - 3.2.2.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004735 311.0
PYH3_k127_862432_11 Haloacid dehalogenase-like hydrolase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000005542 300.0
PYH3_k127_862432_12 Cytidylyltransferase family K00981 - 2.7.7.41 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001798 289.0
PYH3_k127_862432_13 peptidase C14 caspase catalytic subunit p20 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003339 280.0
PYH3_k127_862432_14 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000006984 244.0
PYH3_k127_862432_16 Dienelactone hydrolase family K01061 - 3.1.1.45 0.000000000000000000000000000000000000000000000000001395 192.0
PYH3_k127_862432_17 Belongs to the MEMO1 family K06990 - - 0.0000000000000000000001219 105.0
PYH3_k127_862432_19 - K07184,K07777,K12065,K13527 - 2.7.13.3 0.0000000000000007805 87.0
PYH3_k127_862432_2 Bacterial regulatory protein, Fis family K07715 - - 2.503e-194 617.0
PYH3_k127_862432_20 CO dehydrogenase/acetyl-CoA synthase delta subunit K00548 - 2.1.1.13 0.00000004844 62.0
PYH3_k127_862432_3 Catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate (MEP) K00099 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0006081,GO:0006082,GO:0006090,GO:0006629,GO:0006644,GO:0006720,GO:0006721,GO:0006793,GO:0006796,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009240,GO:0009987,GO:0016114,GO:0016491,GO:0016614,GO:0016616,GO:0019288,GO:0019637,GO:0019682,GO:0019752,GO:0030145,GO:0030604,GO:0032787,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0046490,GO:0046872,GO:0046914,GO:0048037,GO:0050661,GO:0050662,GO:0051483,GO:0051484,GO:0055114,GO:0070402,GO:0071704,GO:0090407,GO:0097159,GO:1901135,GO:1901265,GO:1901363,GO:1901576 1.1.1.267 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001775 580.0
PYH3_k127_862432_4 HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain K07711 - 2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000276 455.0
PYH3_k127_862432_5 Squalene/phytoene synthase K02291 - 2.5.1.32,2.5.1.99 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000966 414.0
PYH3_k127_862432_6 Peptidase family M50 K11749 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000442 408.0
PYH3_k127_862432_7 Flavin containing amine oxidoreductase K21677 - 1.17.8.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003921 357.0
PYH3_k127_862432_8 Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids K00806 - 2.5.1.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006903 347.0
PYH3_k127_862432_9 abc-type fe3 -hydroxamate transport system, periplasmic component K02016 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001029 333.0
PYH3_k127_8690491_0 peptidyl-tyrosine sulfation - - - 2.034e-212 676.0
PYH3_k127_8690491_1 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004739 446.0
PYH3_k127_8690491_12 May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane - GO:0000981,GO:0000982,GO:0001077,GO:0001228,GO:0001775,GO:0002237,GO:0002252,GO:0002376,GO:0002520,GO:0002526,GO:0002682,GO:0002684,GO:0002694,GO:0003674,GO:0003700,GO:0005102,GO:0005154,GO:0005215,GO:0005319,GO:0005488,GO:0005509,GO:0005515,GO:0005548,GO:0005575,GO:0005576,GO:0005622,GO:0005623,GO:0005634,GO:0005730,GO:0005737,GO:0005794,GO:0005829,GO:0005886,GO:0005887,GO:0006139,GO:0006351,GO:0006355,GO:0006357,GO:0006366,GO:0006575,GO:0006629,GO:0006644,GO:0006650,GO:0006658,GO:0006659,GO:0006725,GO:0006793,GO:0006796,GO:0006807,GO:0006810,GO:0006811,GO:0006820,GO:0006869,GO:0006915,GO:0006950,GO:0006952,GO:0006953,GO:0006954,GO:0006955,GO:0007009,GO:0007154,GO:0007165,GO:0007275,GO:0007596,GO:0007599,GO:0008150,GO:0008152,GO:0008219,GO:0008610,GO:0008654,GO:0009058,GO:0009059,GO:0009605,GO:0009607,GO:0009611,GO:0009615,GO:0009617,GO:0009889,GO:0009891,GO:0009893,GO:0009966,GO:0009967,GO:0009987,GO:0010033,GO:0010256,GO:0010467,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010628,GO:0010646,GO:0010647,GO:0010876,GO:0010911,GO:0010912,GO:0010941,GO:0010942,GO:0012501,GO:0012505,GO:0015711,GO:0015748,GO:0015914,GO:0016020,GO:0016021,GO:0016043,GO:0016070,GO:0017121,GO:0017124,GO:0017128,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019637,GO:0019899,GO:0019904,GO:0023051,GO:0023052,GO:0023056,GO:0030097,GO:0030099,GO:0030154,GO:0030168,GO:0031012,GO:0031224,GO:0031226,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0031347,GO:0031349,GO:0031974,GO:0031981,GO:0032091,GO:0032496,GO:0032501,GO:0032502,GO:0032774,GO:0032781,GO:0033003,GO:0033036,GO:0033993,GO:0034097,GO:0034641,GO:0034645,GO:0034654,GO:0035455,GO:0035456,GO:0035556,GO:0042060,GO:0042221,GO:0042398,GO:0042609,GO:0042981,GO:0043065,GO:0043067,GO:0043068,GO:0043085,GO:0043167,GO:0043169,GO:0043170,GO:0043207,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043393,GO:0043462,GO:0043900,GO:0043901,GO:0043903,GO:0044092,GO:0044093,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044271,GO:0044421,GO:0044422,GO:0044424,GO:0044425,GO:0044428,GO:0044444,GO:0044446,GO:0044459,GO:0044464,GO:0045017,GO:0045069,GO:0045071,GO:0045088,GO:0045089,GO:0045121,GO:0045893,GO:0045935,GO:0045944,GO:0046474,GO:0046483,GO:0046486,GO:0046872,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048525,GO:0048534,GO:0048583,GO:0048584,GO:0048731,GO:0048856,GO:0048869,GO:0050776,GO:0050778,GO:0050789,GO:0050790,GO:0050792,GO:0050794,GO:0050817,GO:0050865,GO:0050878,GO:0050896,GO:0051098,GO:0051100,GO:0051171,GO:0051173,GO:0051179,GO:0051234,GO:0051252,GO:0051254,GO:0051336,GO:0051345,GO:0051607,GO:0051704,GO:0051707,GO:0051716,GO:0060255,GO:0060368,GO:0061024,GO:0065007,GO:0065008,GO:0065009,GO:0070013,GO:0070782,GO:0070851,GO:0070887,GO:0071216,GO:0071219,GO:0071222,GO:0071310,GO:0071345,GO:0071396,GO:0071702,GO:0071704,GO:0071840,GO:0071944,GO:0080090,GO:0080134,GO:0080135,GO:0090304,GO:0090407,GO:0097035,GO:0097190,GO:0097193,GO:0097194,GO:0097659,GO:0098542,GO:0098589,GO:0098805,GO:0098857,GO:0140110,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901700,GO:1901701,GO:1902229,GO:1902231,GO:1902531,GO:1902533,GO:1902680,GO:1903506,GO:1903508,GO:1903900,GO:1903901,GO:2000112,GO:2000371,GO:2000373,GO:2001020,GO:2001022,GO:2001141,GO:2001233,GO:2001235,GO:2001242,GO:2001244 - 0.00000000002954 75.0
PYH3_k127_8690491_14 YtxH-like protein - - - 0.00000001773 60.0
PYH3_k127_8690491_15 Antibiotic biosynthesis monooxygenase - - - 0.00000005502 60.0
PYH3_k127_8690491_16 Antibiotic biosynthesis monooxygenase - - - 0.00000007449 60.0
PYH3_k127_8690491_2 Nucleotidyltransferase DNA polymerase involved in DNA repair K03502 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000046 434.0
PYH3_k127_8690491_3 Enoyl-(Acyl carrier protein) reductase K00208 - 1.3.1.10,1.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007142 430.0
PYH3_k127_8690491_4 Cyclic nucleotide-monophosphate binding domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001264 281.0
PYH3_k127_8690491_5 Belongs to the peptidase S24 family K03503 - - 0.00000000000000000000000000000000000000000000000001572 184.0
PYH3_k127_8690491_6 - - - - 0.000000000000000000000000000000000000000000002136 175.0
PYH3_k127_8690491_7 lipid binding - - - 0.0000000000000000000000000000000001147 136.0
PYH3_k127_8690491_8 VIT family - - - 0.000000000000000000000000003084 125.0
PYH3_k127_8695224_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source K01950 - 6.3.5.1 8.173e-265 826.0
PYH3_k127_8695224_1 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 - - 2.171e-249 774.0
PYH3_k127_8695224_10 Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation K02982 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007799 379.0
PYH3_k127_8695224_11 Metallopeptidase family M24 K01265 - 3.4.11.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002171 381.0
PYH3_k127_8695224_12 ABC transporter K06861 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003511 370.0
PYH3_k127_8695224_13 Ammonium Transporter Family K03320 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001225 338.0
PYH3_k127_8695224_14 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 330.0
PYH3_k127_8695224_15 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001266 320.0
PYH3_k127_8695224_16 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004576 314.0
PYH3_k127_8695224_17 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001823 302.0
PYH3_k127_8695224_18 Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs K02878 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003656 259.0
PYH3_k127_8695224_19 Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body K02988 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000001257 256.0
PYH3_k127_8695224_2 ANTAR - - - 4.331e-214 673.0
PYH3_k127_8695224_20 Ribosomal protein L4/L1 family K02926 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044445,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002099 259.0
PYH3_k127_8695224_21 This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center K02933 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000002315 257.0
PYH3_k127_8695224_22 Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome K02948 - - 0.00000000000000000000000000000000000000000000000000000000000000000000004611 241.0
PYH3_k127_8695224_23 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000001379 237.0
PYH3_k127_8695224_24 Pilus assembly protein, PilO K02664 - - 0.0000000000000000000000000000000000000000000000000000000000000001951 229.0
PYH3_k127_8695224_25 binds to the 23S rRNA K02876 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000007202 216.0
PYH3_k127_8695224_26 Protein conserved in bacteria K11719 - - 0.000000000000000000000000000000000000000000000000000000001357 205.0
PYH3_k127_8695224_27 Fimbrial assembly protein (PilN) K02663 - - 0.00000000000000000000000000000000000000000000000000000001634 202.0
PYH3_k127_8695224_28 Involved in the binding of tRNA to the ribosomes K02946 - - 0.00000000000000000000000000000000000000000000000000001404 189.0
PYH3_k127_8695224_29 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000715 186.0
PYH3_k127_8695224_3 Sigma-54 factor, Activator interacting domain (AID) K03092 - - 6.414e-199 634.0
PYH3_k127_8695224_30 Ribosomal protein L17 K02879 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000000000000000000001078 180.0
PYH3_k127_8695224_31 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000001641 177.0
PYH3_k127_8695224_32 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015935,GO:0022626,GO:0022627,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000000000000000000000000000000000000005431 175.0
PYH3_k127_8695224_33 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000000000000000005353 171.0
PYH3_k127_8695224_34 OstA-like protein K09774 - - 0.00000000000000000000000000000000000000000000007929 175.0
PYH3_k127_8695224_35 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 - - 0.00000000000000000000000000000000000000000376 160.0
PYH3_k127_8695224_36 Pilus assembly protein, PilP K02665 - - 0.00000000000000000000000000000000000005684 151.0
PYH3_k127_8695224_37 One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex K02518 GO:0001871,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0009986,GO:0030246,GO:0030247,GO:0043021,GO:0043022,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:2001065 - 0.00000000000000000000000000000000004488 135.0
PYH3_k127_8695224_38 One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit K02895 - - 0.000000000000000000000000000000001716 132.0
PYH3_k127_8695224_39 One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000006623 137.0
PYH3_k127_8695224_4 Secretin and TonB N terminus short domain K02666 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000436 631.0
PYH3_k127_8695224_40 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000266 124.0
PYH3_k127_8695224_41 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K02358 - - 0.000000000000000000000000000001143 121.0
PYH3_k127_8695224_42 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding K11686,K13640,K18997 - - 0.000000000000000000000005309 102.0
PYH3_k127_8695224_43 30S ribosomal protein S14 K02954 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000001168 97.0
PYH3_k127_8695224_44 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) K02907 GO:0000027,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0040007,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000003504 85.0
PYH3_k127_8695224_45 Belongs to the universal ribosomal protein uL29 family K02904 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.000000000000003438 78.0
PYH3_k127_8695224_46 Belongs to the bacterial ribosomal protein bL36 family K02919 - - 0.00000000000008185 71.0
PYH3_k127_8695224_5 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03040 - 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001839 513.0
PYH3_k127_8695224_6 One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006692 477.0
PYH3_k127_8695224_7 Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system K01736 - 4.2.3.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001899 472.0
PYH3_k127_8695224_8 Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) K01735 - 4.2.3.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000407 445.0
PYH3_k127_8695224_9 Type IV pilus assembly protein PilM; K02662 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 428.0
PYH3_k127_8718199_0 AcrB/AcrD/AcrF family K15726 - - 0.0 1517.0
PYH3_k127_8718199_1 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 6.547e-275 857.0
PYH3_k127_8718199_10 DNA import into cell involved in transformation K11070 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001063 312.0
PYH3_k127_8718199_11 deoxyhypusine monooxygenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000009493 294.0
PYH3_k127_8718199_12 Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions K01462 - 3.5.1.88 0.00000000000000000000000000000000000000000000000000000000000000000000000000007062 262.0
PYH3_k127_8718199_13 phosphorelay signal transduction system - - - 0.000000000000000000000000000000000000002833 150.0
PYH3_k127_8718199_14 dead DEAH box helicase K03727 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005886,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009056,GO:0009057,GO:0009987,GO:0016020,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0019439,GO:0030312,GO:0034641,GO:0034655,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0070035,GO:0071704,GO:0071944,GO:0090304,GO:0140098,GO:1901360,GO:1901361,GO:1901575 - 0.00000000000000000004142 93.0
PYH3_k127_8718199_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K06147,K11085 - - 1.263e-253 793.0
PYH3_k127_8718199_3 Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans K00975 - 2.7.7.27 7.574e-204 640.0
PYH3_k127_8718199_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K15725 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006541 558.0
PYH3_k127_8718199_5 Required for the activity of the bacterial periplasmic transport system of putrescine K11069,K11070 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000346 506.0
PYH3_k127_8718199_6 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family K15727 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003286 471.0
PYH3_k127_8718199_7 PhoQ Sensor - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005758 473.0
PYH3_k127_8718199_8 ATPase activity K11072 - 3.6.3.31 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006361 376.0
PYH3_k127_8718199_9 putrescine transport K11071 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002393 353.0
PYH3_k127_8745609_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001684 319.0
PYH3_k127_8745609_1 Prokaryotic dksA/traR C4-type zinc finger K06204 - - 0.0000000000000000000000000000000000000000000000000003404 190.0
PYH3_k127_8745609_2 Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis K00759 - 2.4.2.7 0.00000000000000000000000000000000000000000000000009969 179.0
PYH3_k127_8822497_0 alpha-ribazole phosphatase activity K00850,K21071 - 2.7.1.11,2.7.1.90 0.0 1178.0
PYH3_k127_8822497_1 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 3.07e-215 685.0
PYH3_k127_8822497_10 Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate K03271 - 5.3.1.28 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000124 292.0
PYH3_k127_8822497_11 Metallo-beta-lactamase superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000184 275.0
PYH3_k127_8822497_12 Appr-1-p processing domain protein - - - 0.00000000000000000000000000000000000000000000000000001493 192.0
PYH3_k127_8822497_13 SprT-like family K02742 - - 0.00000000000000000000000000000000000000000000000000006411 196.0
PYH3_k127_8822497_14 cellular response to DNA damage stimulus K07340 - - 0.00000000000000000000000000000000000000000000000000399 185.0
PYH3_k127_8822497_16 Thioesterase-like superfamily K07107 - - 0.000000000000000000000000000000000000000000008176 168.0
PYH3_k127_8822497_18 nuclease - - - 0.000000000000000000001076 104.0
PYH3_k127_8822497_2 Aminotransferase class-III K01845 - 5.4.3.8 7.762e-203 639.0
PYH3_k127_8822497_3 Belongs to the pyruvate kinase family K00873 - 2.7.1.40 1.63e-200 637.0
PYH3_k127_8822497_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003634 595.0
PYH3_k127_8822497_5 peptidyl-tyrosine sulfation - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001498 577.0
PYH3_k127_8822497_6 peptidyl-lysine modification to peptidyl-hypusine - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003834 505.0
PYH3_k127_8822497_7 prohibitin homologues - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000628 485.0
PYH3_k127_8822497_8 Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII K02346 GO:0003674,GO:0003824,GO:0003887,GO:0006139,GO:0006259,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016740,GO:0016772,GO:0016779,GO:0018130,GO:0019438,GO:0033554,GO:0034061,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0071897,GO:0090304,GO:0140097,GO:1901360,GO:1901362,GO:1901576 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003997 405.0
PYH3_k127_8822497_9 HAD-hyrolase-like K01091 - 3.1.3.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002918 349.0
PYH3_k127_8939267_0 L-allo-threonine aldolase activity K01620 - 4.1.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002725 463.0
PYH3_k127_8939267_1 Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins K13292 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001884 392.0
PYH3_k127_8939267_11 sequence-specific DNA binding - - - 0.000000000000000000000000005198 111.0
PYH3_k127_8939267_12 photosynthesis - - - 0.00000000000000002335 88.0
PYH3_k127_8939267_13 gas vesicle protein - - - 0.000000000000001284 81.0
PYH3_k127_8939267_2 Alpha/beta hydrolase family K01061 - 3.1.1.45 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001252 312.0
PYH3_k127_8939267_3 nucleotidyltransferase activity K17882 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002784 308.0
PYH3_k127_8939267_4 inositol 2-dehydrogenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001097 278.0
PYH3_k127_8939267_7 Zincin-like metallopeptidase - - - 0.0000000000000000000000000000000000000000001991 161.0
PYH3_k127_8939267_8 Protein of unknown function (DUF423) - - - 0.000000000000000000000000000000000000000003126 158.0
PYH3_k127_8939267_9 PD-(D/E)XK nuclease superfamily - - - 0.0000000000000000000000000000001059 131.0
PYH3_k127_8945831_0 thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence K02945 - - 1.617e-306 947.0
PYH3_k127_8945831_1 glutamate dehydrogenase [NAD(P)+] activity K00261,K00262 - 1.4.1.3,1.4.1.4 3.455e-219 689.0
PYH3_k127_8945831_10 oxidoreductase activity, acting on CH-OH group of donors - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002017 315.0
PYH3_k127_8945831_11 Belongs to the peptidase S11 family K07258 - 3.4.16.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001169 319.0
PYH3_k127_8945831_12 PFAM Band 7 protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001909 312.0
PYH3_k127_8945831_13 Belongs to the cytidylate kinase family. Type 1 subfamily K00945 GO:0003674,GO:0003824,GO:0004127,GO:0004592,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006520,GO:0006573,GO:0006575,GO:0006725,GO:0006732,GO:0006753,GO:0006766,GO:0006767,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009081,GO:0009108,GO:0009110,GO:0009117,GO:0009123,GO:0009165,GO:0009987,GO:0015939,GO:0015940,GO:0016053,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0016874,GO:0016879,GO:0016881,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019752,GO:0032787,GO:0033317,GO:0034641,GO:0034654,GO:0042364,GO:0042398,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046483,GO:0046939,GO:0046940,GO:0050145,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072330,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605 2.7.4.25 0.000000000000000000000000000000000000000000000000000000000000000000000000000002317 268.0
PYH3_k127_8945831_14 lipoyl(octanoyl) transferase activity K03644,K03801 GO:0003674,GO:0003824,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016053,GO:0016415,GO:0016740,GO:0016746,GO:0016747,GO:0016772,GO:0016779,GO:0016874,GO:0016879,GO:0016979,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019222,GO:0019538,GO:0019752,GO:0032787,GO:0033819,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046483,GO:0048519,GO:0050789,GO:0051186,GO:0051188,GO:0051604,GO:0060255,GO:0065007,GO:0071704,GO:0072330,GO:0140096,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.3.1.181,2.8.1.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000001097 268.0
PYH3_k127_8945831_16 Phosphate acyltransferases K00655 - 2.3.1.51 0.0000000000000000000000000000000000000000000000000000000000000000000003651 244.0
PYH3_k127_8945831_18 bacterial (prokaryotic) histone like domain K05788 - - 0.0000000000000000000000000000000000000000007893 158.0
PYH3_k127_8945831_2 amine dehydrogenase activity - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004028 502.0
PYH3_k127_8945831_23 Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA) K00014 GO:0000166,GO:0003674,GO:0003824,GO:0004764,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016491,GO:0016614,GO:0016616,GO:0019632,GO:0019752,GO:0032787,GO:0036094,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0046417,GO:0048037,GO:0050661,GO:0050662,GO:0055114,GO:0071704,GO:0097159,GO:1901265,GO:1901363,GO:1901576,GO:1901615 1.1.1.25 0.00000000000009586 71.0
PYH3_k127_8945831_3 Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3- phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate K00800 GO:0003674,GO:0003824,GO:0003866,GO:0006082,GO:0008150,GO:0008152,GO:0009058,GO:0009423,GO:0009987,GO:0016053,GO:0016740,GO:0016765,GO:0019752,GO:0043436,GO:0043648,GO:0043650,GO:0044237,GO:0044249,GO:0044281,GO:0044283,GO:0046394,GO:0046417,GO:0071704,GO:1901576 2.5.1.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002148 490.0
PYH3_k127_8945831_4 Proto-chlorophyllide reductase 57 kD subunit - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005094 477.0
PYH3_k127_8945831_5 Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released K03086 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000013 460.0
PYH3_k127_8945831_6 Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA K07442 - 2.1.1.219,2.1.1.220 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000192 429.0
PYH3_k127_8945831_7 NfeD-like C-terminal, partner-binding K07403 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002123 432.0
PYH3_k127_8945831_8 Peptidase family S49 K04773 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002096 405.0
PYH3_k127_8945831_9 serine-type endopeptidase activity K04771 - 3.4.21.107 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004803 389.0
PYH3_k127_9013910_0 - - - - 0.00000000000000000000000004594 117.0
PYH3_k127_9013910_1 PFAM Sodium hydrogen exchanger family - - - 0.00000000000001386 74.0
PYH3_k127_906462_0 glutamate-tRNA ligase activity K01886 GO:0003674,GO:0003824,GO:0004812,GO:0004819,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006425,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.18 9.99e-290 897.0
PYH3_k127_906462_1 tRNA processing K04075,K14058,K21947 GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016782,GO:0016783,GO:0034227,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0071704,GO:0090304,GO:1901360 2.8.1.15,6.3.4.19 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003493 452.0
PYH3_k127_906462_2 peptide-methionine (S)-S-oxide reductase activity K07304,K12267 - 1.8.4.11,1.8.4.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001956 292.0
PYH3_k127_906462_3 Transglutaminase/protease-like homologues - - - 0.000000000000000000000000000000000000000000000000000000000004994 228.0
PYH3_k127_906462_4 Belongs to the low molecular weight phosphotyrosine protein phosphatase family K01104,K03741 - 1.20.4.1,3.1.3.48 0.000000000000000000000000000000000000000000000000000000248 197.0
PYH3_k127_9077558_0 Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family K03296 - - 1.601e-247 792.0
PYH3_k127_9077558_1 PFAM Outer membrane efflux protein - - - 0.0000000000000000000000000000000000003403 152.0
PYH3_k127_9077558_2 Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family - - - 0.000000000000000000000000000002592 136.0
PYH3_k127_9167936_0 In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity K02335 - 2.7.7.7 2.446e-242 764.0
PYH3_k127_9167936_1 - - - - 0.0000000000000000000000000000000000000000000002554 172.0
PYH3_k127_920678_0 One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex K02519 - - 0.0 1029.0
PYH3_k127_920678_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K00012 - 1.1.1.22 2.3e-220 694.0
PYH3_k127_920678_10 signal-transduction protein containing cAMP-binding and CBS domains K02342,K05847,K07182 - 2.7.7.7 0.000000000000000000000000000000000000000000001273 169.0
PYH3_k127_920678_11 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K00363,K05710 - 1.7.1.15 0.00000000000000000000000000000000000000000004757 167.0
PYH3_k127_920678_2 spermidine synthase activity K00797 - 2.5.1.16 2.817e-211 669.0
PYH3_k127_920678_3 Participates in both transcription termination and antitermination K02600 - - 2.015e-202 635.0
PYH3_k127_920678_4 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000175 379.0
PYH3_k127_920678_5 branched-chain-amino-acid transaminase activity K00824 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0006520,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008483,GO:0008652,GO:0009056,GO:0009058,GO:0009063,GO:0009987,GO:0016053,GO:0016054,GO:0016740,GO:0016769,GO:0019478,GO:0019752,GO:0019842,GO:0030170,GO:0036094,GO:0043167,GO:0043168,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044281,GO:0044282,GO:0044283,GO:0046394,GO:0046395,GO:0046416,GO:0046437,GO:0047810,GO:0048037,GO:0050662,GO:0070279,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901565,GO:1901566,GO:1901575,GO:1901576,GO:1901605,GO:1901606,GO:1901607 2.6.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001227 369.0
PYH3_k127_920678_7 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000003411 235.0
PYH3_k127_920678_8 Uncharacterized ACR, COG1430 K09005 - - 0.0000000000000000000000000000000000000000000000001281 181.0
PYH3_k127_920678_9 Required for maturation of 30S ribosomal subunits K09748 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576 - 0.00000000000000000000000000000000000000000000001644 176.0
PYH3_k127_9269549_0 DegT/DnrJ/EryC1/StrS aminotransferase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001009 557.0
PYH3_k127_9269549_1 beta-fructofuranosidase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007681 338.0
PYH3_k127_9269549_2 involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell K00677 - 2.3.1.129 0.0000000000000000000000000000000000000000000000000000000000000000000000007471 251.0
PYH3_k127_9269549_3 transferase activity, transferring glycosyl groups - - - 0.0000000000000000000000000000000000000000005177 173.0
PYH3_k127_9269549_4 glycosyl transferase group 1 - - - 0.00000000000000000000000000000002325 140.0
PYH3_k127_9269549_5 Nucleotidyl transferase - - - 0.0000000000001515 79.0
PYH3_k127_9397607_0 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00382 - 1.8.1.4 5.54e-229 716.0
PYH3_k127_9397607_1 methyltransferase - - - 2.279e-224 721.0
PYH3_k127_9397607_10 protein trimerization K01206,K07114,K07126 - 3.2.1.51 0.00000000000000000000000000000000000000000000003185 190.0
PYH3_k127_9397607_13 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.000000000000000000000000000001473 124.0
PYH3_k127_9397607_14 Belongs to the bacterial ribosomal protein bL28 family K02902 - - 0.0000000000000000000000003884 108.0
PYH3_k127_9397607_15 photosystem II stabilization K00703,K02237,K02238 - 2.4.1.21 0.000000000000000003496 89.0
PYH3_k127_9397607_16 Helix-turn-helix domain - - - 0.000000000000002053 80.0
PYH3_k127_9397607_2 Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA) K03655 - 3.6.4.12 1.46e-204 663.0
PYH3_k127_9397607_3 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 - 6.1.1.1 1.395e-201 634.0
PYH3_k127_9397607_4 Evidence 3 Function proposed based on presence of conserved amino acid motif, structural feature or limited homology K01524 - 3.6.1.11,3.6.1.40 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001904 374.0
PYH3_k127_9397607_5 Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P) K08963 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0006082,GO:0006520,GO:0006555,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009987,GO:0016053,GO:0016853,GO:0016860,GO:0016861,GO:0017144,GO:0019509,GO:0019752,GO:0043094,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044272,GO:0044281,GO:0044283,GO:0046394,GO:0046523,GO:0071265,GO:0071267,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 5.3.1.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000492 321.0
PYH3_k127_9397607_6 Carboxylesterase family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000158 323.0
PYH3_k127_9397607_7 Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine K00684 - 2.3.2.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 302.0
PYH3_k127_9397607_8 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.0000000000000000000000000000000000000000000000000000000000000000001973 232.0
PYH3_k127_9397607_9 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000000000000000000000000000000000002859 213.0
PYH3_k127_9439269_0 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate K03701 - - 0.0 1447.0
PYH3_k127_9439269_1 Molydopterin dinucleotide binding domain K00123 - 1.17.1.9 0.0 1287.0
PYH3_k127_9439269_10 Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001458 381.0
PYH3_k127_9439269_11 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00338 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004857 342.0
PYH3_k127_9439269_12 2 iron, 2 sulfur cluster binding K00334,K03943 - 1.6.5.3,1.6.99.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002053 308.0
PYH3_k127_9439269_13 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00331 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001414 299.0
PYH3_k127_9439269_14 polysaccharide deacetylase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003865 277.0
PYH3_k127_9439269_15 Virulence factor BrkB K07058 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000008715 255.0
PYH3_k127_9439269_16 Glyoxalase-like domain K01759 - 4.4.1.5 0.000000000000000000000000000000000000000000000000000000000000000000002515 236.0
PYH3_k127_9439269_17 acetyltransferase K22278 - 3.5.1.104 0.0000000000000000000000000000000000000000000000000000000000005703 214.0
PYH3_k127_9439269_18 Protein conserved in bacteria K09922 - - 0.000000000000000000000000000000000000000000000000000000000008797 209.0
PYH3_k127_9439269_19 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00340 GO:0003674,GO:0003824,GO:0003954,GO:0005575,GO:0005623,GO:0005886,GO:0008137,GO:0008150,GO:0008152,GO:0016020,GO:0016491,GO:0016651,GO:0016655,GO:0030964,GO:0032991,GO:0044425,GO:0044459,GO:0044464,GO:0045271,GO:0045272,GO:0050136,GO:0055114,GO:0070469,GO:0070470,GO:0071944,GO:0098796,GO:0098797,GO:0098803,GO:1902494,GO:1990204 1.6.5.3 0.0000000000000000000000000000000000003396 143.0
PYH3_k127_9439269_2 helicase activity - - - 0.0 1150.0
PYH3_k127_9439269_20 Belongs to the complex I subunit 6 family K00339 - 1.6.5.3 0.00000000000000000000000000000000002668 142.0
PYH3_k127_9439269_21 SnoaL-like polyketide cyclase - - - 0.000000000000000000000000000000001281 135.0
PYH3_k127_9439269_3 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00333,K13378 - 1.6.5.3 0.0 999.0
PYH3_k127_9439269_4 NADH-quinone oxidoreductase K00341 - 1.6.5.3 1.672e-315 975.0
PYH3_k127_9439269_5 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision K03703 - - 7.679e-303 939.0
PYH3_k127_9439269_6 NADH-ubiquinone oxidoreductase-F iron-sulfur binding region K00335 - 1.6.5.3 8.133e-242 751.0
PYH3_k127_9439269_7 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 5.73e-232 731.0
PYH3_k127_9439269_8 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00343 - 1.6.5.3 5.092e-211 666.0
PYH3_k127_9439269_9 NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone K00337 - 1.6.5.3 6.366e-196 614.0
PYH3_k127_9522045_0 ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP K03544 GO:0000166,GO:0003674,GO:0003824,GO:0004176,GO:0005488,GO:0005524,GO:0006508,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017076,GO:0017111,GO:0019538,GO:0030163,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0042623,GO:0043167,GO:0043168,GO:0043170,GO:0044238,GO:0051301,GO:0070011,GO:0071704,GO:0097159,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005493 601.0
PYH3_k127_9522045_1 ABC-type branched-chain amino acid transport systems, periplasmic component K01999 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008272 595.0
PYH3_k127_9522045_10 peroxiredoxin activity - - - 0.00000000000000000000000000000000000000000000005196 172.0
PYH3_k127_9522045_11 deoxyhypusine monooxygenase activity K05386 - - 0.00000000000000000000000000000000000002168 154.0
PYH3_k127_9522045_12 CGNR zinc finger - - - 0.000000000000000000000000000000000009809 143.0
PYH3_k127_9522045_15 Resolvase - - - 0.00025 45.0
PYH3_k127_9522045_2 proline dipeptidase activity K01262 - 3.4.11.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004973 579.0
PYH3_k127_9522045_3 DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity K02343 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000316 576.0
PYH3_k127_9522045_4 Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation. Functions as a peptidyl-prolyl cis-trans isomerase K03545 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001274 569.0
PYH3_k127_9522045_5 deoxyhypusine monooxygenase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003592 453.0
PYH3_k127_9522045_6 Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins K01358 - 3.4.21.92 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003664 379.0
PYH3_k127_9522045_7 protein secretion K03116 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000226 268.0
PYH3_k127_9522045_8 Pyridoxamine 5'-phosphate oxidase K07006 - - 0.000000000000000000000000000000000000000000000000000000000000000002928 231.0
PYH3_k127_9522045_9 PilZ domain K02676 - - 0.0000000000000000000000000000000000000000000000000000004974 199.0
PYH3_k127_9530535_0 PEP-utilising enzyme, mobile domain K01007 - 2.7.9.2 4.923e-199 649.0
PYH3_k127_9530535_1 RmuC family K09760 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000507 322.0
PYH3_k127_9530535_2 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000003171 130.0
PYH3_k127_9530535_3 Belongs to the ompA family K03640 - - 0.00000000000000000000000000001742 124.0
PYH3_k127_9628634_0 alcohol dehydrogenase K00060,K07777 - 1.1.1.103,2.7.13.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002337 565.0
PYH3_k127_9628634_1 alcohol dehydrogenase K13953 - 1.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000245 422.0
PYH3_k127_9628634_2 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639 - 2.3.1.29 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001084 311.0
PYH3_k127_9628634_3 antisigma factor binding K03598 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000008255 287.0
PYH3_k127_9663627_0 WD40-like Beta Propeller Repeat K03641 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003258 570.0
PYH3_k127_9663627_1 Belongs to the ompA family K03640 - - 0.0000000000000000000000000000000000000000000000004001 183.0
PYH3_k127_9663627_2 energy transducer activity K03646,K03832 - - 0.00000000000000000000000002241 116.0
PYH3_k127_9663627_3 Transposase K01991,K02557,K07161,K07484 - - 0.00000000000000001162 94.0
PYH3_k127_9789703_0 AcrB/AcrD/AcrF family - - - 0.0 1660.0
PYH3_k127_9789703_1 HlyD family secretion protein K03585 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000264 553.0
PYH3_k127_9789703_2 TIGRFAM phosphoenolpyruvate phosphomutase K01841 - 5.4.2.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001354 534.0
PYH3_k127_9789703_3 Protein of unknown function (DUF2914) - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007254 407.0
PYH3_k127_9789703_4 Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000126 259.0
PYH3_k127_9789703_8 Bacterial regulatory proteins, tetR family K09017 - - 0.0000000000003854 78.0
PYH3_k127_98878_0 S-layer homology domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005408 330.0
PYH3_k127_98878_1 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000001671 304.0
PYH3_k127_98878_2 Adenylyl- / guanylyl cyclase, catalytic domain K01768 - 4.6.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003464 297.0
PYH3_k127_98878_3 - - - - 0.0000000000000000000000000000000000000000000000000000000000000000000002017 248.0
PYH3_k127_98878_4 Lipoprotein - - - 0.000000000000000000000000000000000000000009526 164.0
PYH3_k127_98878_5 - - - - 0.0000000000000000000000000000000000000000394 164.0
PYH3_k127_98878_6 Domain of unknown function (DUF4384) - - - 0.000000000000000000000000000000000002123 150.0