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Overview

ID MAG03236
Name PYH3_bin.43
Sample SMP0075
Taxonomy
Kingdom Archaea
Phylum Thermoplasmatota
Class Thermoplasmata
Order RBG-16-68-12
Family RBG-16-68-12
Genus EA-19
Species
Assembly information
Completeness (%) 79.51
Contamination (%) 0.65
GC content (%) 68.0
N50 (bp) 5,100
Genome size (bp) 1,425,796

Location

Module

Module ID Module name Total genes Total steps Contain genes Contain steps Percentage of genes Percentage of steps

Genes1327

Gene name Description KEGG GOs EC E-value Score Sequence
PYH3_k127_107225_0 NUDIX domain K03575 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000005228 299.0
PYH3_k127_107225_1 Specifically catalyzes the N1-methylation of pseudouridine at position 54 (Psi54) in tRNAs K16317 - 2.1.1.257 0.0000000000000000000000000000000000000000000003373 178.0
PYH3_k127_107225_2 Aminotransferase - - - 0.0000000000000000000000000000000000000000001875 177.0
PYH3_k127_107225_3 Peptidase family M28 K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000003764 175.0
PYH3_k127_107225_4 Responsible for removing an oxidatively damaged form of guanine (7,8-dihydro-8-oxoguanine 7-oxoG) from DNA. Also nicks DNA at apurinic apyrimidinic sites (AP sites) K03653 - 4.2.99.18 0.000000000000000000000000000000000000006325 151.0
PYH3_k127_107225_5 Quinolinate phosphoribosyl transferase, C-terminal domain K00763 - 6.3.4.21 0.0000000000000000000000001527 122.0
PYH3_k127_1081619_0 PFAM transferase hexapeptide repeat containing protein K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000001463 203.0
PYH3_k127_1081619_1 snRNP Sm proteins K04796 - - 0.00000000000000000000001502 102.0
PYH3_k127_1081619_2 peptidase U32 K08303 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000001782 88.0
PYH3_k127_1081619_3 zinc-ribbon family - - - 0.00006949 51.0
PYH3_k127_1082388_0 aminopeptidase K01256 - 3.4.11.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000207 564.0
PYH3_k127_1082388_1 Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide K00639,K00652,K01620 - 2.3.1.29,2.3.1.47,4.1.2.48 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002911 422.0
PYH3_k127_1082388_2 Catalyzes the NAD( )-dependent oxidation of L-threonine to 2-amino-3-ketobutyrate K00060 - 1.1.1.103 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002354 351.0
PYH3_k127_1082388_3 ATP-NAD AcoX kinase K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002996 349.0
PYH3_k127_1082388_4 NADPH-dependent F420 reductase K06988 - 1.5.1.40 0.0000000000000000000000000000000000000000000000004147 183.0
PYH3_k127_1082388_5 homolog of gamma-carboxymuconolactone decarboxylase subunit - - - 0.00000000000000000000000000000000000000000000003148 172.0
PYH3_k127_1082388_6 transcriptional - - - 0.0000000000000000000001334 100.0
PYH3_k127_1082388_7 Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions K02428 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009058,GO:0009141,GO:0009143,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046434,GO:0046483,GO:0046700,GO:0047429,GO:0055086,GO:0071704,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901575,GO:1901576 3.6.1.66 0.000000000000001518 85.0
PYH3_k127_1082388_8 Cholesterol oxidase K03333 - 1.1.3.6 0.0006046 45.0
PYH3_k127_1103073_0 Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and or for immediate growth after restoration of oxygen K00525 - 1.17.4.1 1.004e-259 822.0
PYH3_k127_1103073_1 Belongs to the Glu Leu Phe Val dehydrogenases family K00260,K00261,K00262 - 1.4.1.2,1.4.1.3,1.4.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005163 529.0
PYH3_k127_1103073_2 Electron transfer flavoprotein alpha subunit K03522 - - 0.0000000000000000000000000000000000000000000000000000000000000001468 233.0
PYH3_k127_1103073_3 D-isomer specific 2-hydroxyacid dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000004764 233.0
PYH3_k127_1103073_4 Electron transfer flavoprotein K03521 - - 0.0000000000000000000000000000000000000000000000000002757 202.0
PYH3_k127_1103073_5 The glycine cleavage system catalyzes the degradation of glycine K00605 GO:0005575,GO:0005618,GO:0005623,GO:0008150,GO:0030312,GO:0040007,GO:0044464,GO:0071944 2.1.2.10 0.0000000000009751 69.0
PYH3_k127_1120370_0 TIGRFAM Outer membrane protein K20276 - - 0.000000000000001655 90.0
PYH3_k127_1131622_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002284 302.0
PYH3_k127_1131622_1 ABC-type multidrug transport system ATPase component K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000436 239.0
PYH3_k127_1131622_2 protein catabolic process K03420,K13525,K17681 - - 0.0000000000000000000000000000000000000000000000000001012 201.0
PYH3_k127_1131622_3 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.0000000000000000000456 93.0
PYH3_k127_1131622_4 ABC-2 type transporter K01992 - - 0.000000000000000001133 96.0
PYH3_k127_1131622_5 PFAM membrane-flanked domain - - - 0.00003236 53.0
PYH3_k127_1131622_6 Regulatory protein MarR - - - 0.0004101 50.0
PYH3_k127_1147529_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.0 1061.0
PYH3_k127_1147529_1 Belongs to the acetyltransferase family. ArgA subfamily - - - 0.000000000000000000000000000000000000000000000000002533 186.0
PYH3_k127_1147529_2 Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline K00611 - 2.1.3.3 0.000005466 51.0
PYH3_k127_1181936_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0 1043.0
PYH3_k127_1181936_1 Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family K00384,K03671 GO:0000166,GO:0001666,GO:0003674,GO:0003824,GO:0004791,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006950,GO:0008150,GO:0008152,GO:0009628,GO:0009636,GO:0009987,GO:0015035,GO:0015036,GO:0016209,GO:0016491,GO:0016651,GO:0016667,GO:0016668,GO:0019725,GO:0036094,GO:0036293,GO:0040007,GO:0042221,GO:0042592,GO:0043167,GO:0043168,GO:0044424,GO:0044444,GO:0044464,GO:0045454,GO:0048037,GO:0050660,GO:0050661,GO:0050662,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0065008,GO:0070402,GO:0070482,GO:0070887,GO:0097159,GO:0097237,GO:0098754,GO:0098869,GO:1901265,GO:1901363,GO:1990748 1.8.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002472 391.0
PYH3_k127_1181936_2 Cysteine-rich domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008024 370.0
PYH3_k127_1181936_3 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000002312 279.0
PYH3_k127_1181936_4 PFAM methyl-viologen-reducing hydrogenase delta subunit K14127 - 1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000001688 184.0
PYH3_k127_1181936_5 Pyridine nucleotide-disulphide oxidoreductase K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000003814 93.0
PYH3_k127_1181936_6 - - - - 0.000000000000001586 91.0
PYH3_k127_1181936_7 Peptidase C13 family - - - 0.00000001282 67.0
PYH3_k127_1234374_0 Could be responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs K06176 GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0016070,GO:0016853,GO:0016866,GO:0034641,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 5.4.99.27 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006204 346.0
PYH3_k127_1234374_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03056 - 2.7.7.6 0.0000000000003197 72.0
PYH3_k127_1257225_0 von Willebrand factor, type A - - - 0.000000000000000001139 101.0
PYH3_k127_1257225_1 Protein of unknown function (DUF1349) - - - 0.0000001791 64.0
PYH3_k127_131174_0 - - - - 0.000000000000000000138 98.0
PYH3_k127_131174_1 - - - - 0.0000000000000005189 87.0
PYH3_k127_131174_2 - - - - 0.00000000000004628 79.0
PYH3_k127_131174_3 alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen - - - 0.0001 54.0
PYH3_k127_1315542_0 Archaeal Nre, N-terminal - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005768 383.0
PYH3_k127_1315542_1 Cytidine and deoxycytidylate deaminase zinc-binding region K01489 - 3.5.4.5 0.00000000000000000000000000002806 121.0
PYH3_k127_1315542_2 PRC-barrel domain protein - - - 0.00005644 45.0
PYH3_k127_1320968_0 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007184 360.0
PYH3_k127_1320968_1 DUF72 domain containing protein - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000002444 270.0
PYH3_k127_1320968_2 Protein of unknown function DUF72 - - - 0.0000000000001394 79.0
PYH3_k127_1320968_3 Transcription factor zinc-finger K09981 - - 0.00000000000686 72.0
PYH3_k127_1329944_0 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03167 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022613,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 5.99.1.3 1.087e-224 722.0
PYH3_k127_1329944_1 Relaxes both positive and negative superturns and exhibits a strong decatenase activity K03166 GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0003916,GO:0003918,GO:0004518,GO:0004519,GO:0004520,GO:0004536,GO:0005488,GO:0006139,GO:0006259,GO:0006725,GO:0006807,GO:0008094,GO:0008150,GO:0008152,GO:0009987,GO:0016462,GO:0016787,GO:0016788,GO:0016817,GO:0016818,GO:0016853,GO:0016887,GO:0016889,GO:0016894,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0061505,GO:0071704,GO:0090304,GO:0090305,GO:0097159,GO:0140097,GO:1901360,GO:1901363 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004534 539.0
PYH3_k127_1329944_2 oxidoreductase subunit alpha K00169 - 1.2.7.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009079 367.0
PYH3_k127_1329944_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001593 322.0
PYH3_k127_1329944_4 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism K00939 - 2.7.4.3 0.00000000000000000000000000000000000000000000000000000000000000000001335 239.0
PYH3_k127_1329944_5 oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor K00171,K00172,K18358,K19072 GO:0003674,GO:0003824,GO:0005488,GO:0006082,GO:0008150,GO:0008152,GO:0009056,GO:0009987,GO:0016054,GO:0016491,GO:0016625,GO:0016903,GO:0019752,GO:0033609,GO:0033611,GO:0043436,GO:0043648,GO:0043649,GO:0044237,GO:0044248,GO:0044281,GO:0044282,GO:0046395,GO:0048037,GO:0051536,GO:0051539,GO:0051540,GO:0055114,GO:0071704,GO:1901575 1.2.1.58,1.2.7.1,1.2.7.10 0.0000000000000000000000000000000000000000000000000005748 196.0
PYH3_k127_1329944_6 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.00000000000000000000000000000000000000000000000001951 185.0
PYH3_k127_1329944_7 PFAM Aspartate glutamate uridylate kinase K00926 - 2.7.2.2 0.00000000000000000000000000000000004182 138.0
PYH3_k127_1329944_8 VanZ like family - - - 0.00000000006939 69.0
PYH3_k127_1330799_0 ABC-type multidrug transport system ATPase K01990,K16907 - - 0.00000000000000000000000000000000000000000000000001927 186.0
PYH3_k127_1330799_1 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.000000001414 66.0
PYH3_k127_1330799_2 Dodecin K09165 - - 0.00003261 50.0
PYH3_k127_1330799_3 PFAM SpoVT AbrB K07172 - - 0.0001075 47.0
PYH3_k127_1443135_0 Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP K01939 - 6.3.4.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 454.0
PYH3_k127_1443135_1 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000000000000000000007038 189.0
PYH3_k127_1473281_0 Belongs to the enoyl-CoA hydratase isomerase family K15016 - 1.1.1.35,4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001226 499.0
PYH3_k127_1473281_1 PFAM NHL repeat containing protein - - - 0.000000000000000000000000000000000000000000000003043 197.0
PYH3_k127_1487720_0 The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently K03076 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 - 5.066e-198 630.0
PYH3_k127_1487720_1 With S4 and S12 plays an important role in translational accuracy K02988 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008524 317.0
PYH3_k127_1487720_2 This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance K02881 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008097,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000001449 178.0
PYH3_k127_1487720_3 Ribosomal protein L30 K02907 GO:0000463,GO:0000470,GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000231 156.0
PYH3_k127_1487720_4 ribosomal protein L15 K02876 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000007803 120.0
PYH3_k127_1493396_0 COG0683 ABC-type branched-chain amino acid transport systems, periplasmic component - - - 0.000000000000000000000000000000000001236 159.0
PYH3_k127_1493396_1 Prenyltransferase K13277 - - 0.0000001143 63.0
PYH3_k127_1493396_2 PFAM TM2 domain containing protein - - - 0.000003143 56.0
PYH3_k127_149765_0 Mandelate racemase / muconate lactonizing enzyme, C-terminal domain K19802 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016853,GO:0016854,GO:0034641,GO:0043167,GO:0043169,GO:0043603,GO:0044237,GO:0046872,GO:0071704,GO:1901564 5.1.1.20 0.00000000000000000000000000000000000000000000000000000000000000000001026 250.0
PYH3_k127_149765_1 DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate K10773 - 4.2.99.18 0.000000000000000000000000000000000000000000000000000000000001388 218.0
PYH3_k127_149765_2 Belongs to the folylpolyglutamate synthase family K11754 - 6.3.2.12,6.3.2.17 0.00002354 48.0
PYH3_k127_1535899_0 COG1012 NAD-dependent aldehyde dehydrogenases K00140 - 1.2.1.18,1.2.1.27 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003999 496.0
PYH3_k127_1535899_1 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K00823,K07250 - 2.6.1.19,2.6.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009566 390.0
PYH3_k127_1535899_2 Major Facilitator K08369 - - 0.00000000000000000000000000000001936 132.0
PYH3_k127_1575748_0 Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation K01874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.10 3.253e-226 724.0
PYH3_k127_1575748_1 Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions - - - 0.00000000000000000000000000000000000000000000000000000000000004194 217.0
PYH3_k127_1575748_2 6,7-dimethyl-8-ribityllumazine synthase K00793 - 2.5.1.9 0.00000000000000000000000000000000000000000000000000000003543 209.0
PYH3_k127_1575748_3 Catalyzes the transfer of the AMP portion of ATP to flavin mononucleotide (FMN) to produce flavin adenine dinucleotide (FAD) coenzyme K14656 GO:0000166,GO:0001882,GO:0001884,GO:0002135,GO:0003674,GO:0003824,GO:0003919,GO:0005488,GO:0005515,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006747,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009123,GO:0009161,GO:0009165,GO:0009259,GO:0009987,GO:0010181,GO:0016740,GO:0016772,GO:0016779,GO:0017076,GO:0018130,GO:0019103,GO:0019438,GO:0019637,GO:0019693,GO:0030554,GO:0032549,GO:0032551,GO:0032553,GO:0032555,GO:0032557,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042726,GO:0042727,GO:0042802,GO:0042803,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046443,GO:0046444,GO:0046483,GO:0046983,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0055086,GO:0070566,GO:0071704,GO:0072387,GO:0072388,GO:0090407,GO:0097159,GO:0097367,GO:1901135,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.7.2 0.000000000000000000000000000000000000000000491 168.0
PYH3_k127_1575748_4 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.000000000000000000000000000000000000000002321 162.0
PYH3_k127_1575748_5 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.00000000000000000000000000000000000005584 145.0
PYH3_k127_1575748_6 Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin K00794 GO:0000906,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016740,GO:0016765,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.5.1.78 0.0000000000000000000000000000000481 137.0
PYH3_k127_1575748_7 PFAM Deoxyribonuclease rho motif-related TRAM - - - 0.0000000000000000227 85.0
PYH3_k127_1575748_8 Roadblock/LC7 domain K07131 - - 0.00004683 51.0
PYH3_k127_1606682_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005551 407.0
PYH3_k127_1606682_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001632 335.0
PYH3_k127_1606682_10 Acetyltransferase (GNAT) domain - - - 0.00000000004813 74.0
PYH3_k127_1606682_11 Belongs to the eukaryotic ribosomal protein eL33 family K02917 - - 0.00003382 55.0
PYH3_k127_1606682_2 Belongs to the class-II aminoacyl-tRNA synthetase family K01868 - 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000008031 267.0
PYH3_k127_1606682_3 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000009247 257.0
PYH3_k127_1606682_4 transport system, permease component K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000001161 248.0
PYH3_k127_1606682_5 Ribbon-helix-helix protein, copG family K07722 - - 0.00000000000000000001799 94.0
PYH3_k127_1606682_6 PFAM CBS domain containing protein - - - 0.0000000000000000001931 94.0
PYH3_k127_1606682_7 - - - - 0.0000000000000002594 81.0
PYH3_k127_1606682_8 pfam nudix - - - 0.00000000000002583 83.0
PYH3_k127_1606682_9 lyase activity - - - 0.00000000000002687 85.0
PYH3_k127_1608754_0 Protein of unknown function (DUF3494) - - - 0.0000000000000000000000000000000001067 155.0
PYH3_k127_1608754_1 Sulfatase-modifying factor enzyme 1 K01176,K01206,K01218,K01219,K01224 - 3.2.1.1,3.2.1.51,3.2.1.78,3.2.1.81,3.2.1.89 0.00000000000000004505 98.0
PYH3_k127_1608754_2 Belongs to the peptidase S8 family K13276 - - 0.00000000005508 78.0
PYH3_k127_1608754_3 It is involved in the biological process described with multicellular organismal development - GO:0001501,GO:0001558,GO:0001568,GO:0001667,GO:0001702,GO:0001944,GO:0002009,GO:0002011,GO:0003002,GO:0003007,GO:0003143,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0006355,GO:0006357,GO:0006928,GO:0007154,GO:0007165,GO:0007166,GO:0007167,GO:0007178,GO:0007275,GO:0007368,GO:0007369,GO:0007389,GO:0007399,GO:0007413,GO:0007507,GO:0008037,GO:0008038,GO:0008150,GO:0008361,GO:0008589,GO:0009653,GO:0009719,GO:0009790,GO:0009792,GO:0009799,GO:0009855,GO:0009887,GO:0009888,GO:0009889,GO:0009966,GO:0009968,GO:0009987,GO:0010033,GO:0010468,GO:0010556,GO:0010646,GO:0010648,GO:0010720,GO:0010769,GO:0010770,GO:0010975,GO:0010976,GO:0016043,GO:0016477,GO:0019219,GO:0019222,GO:0022008,GO:0022603,GO:0022604,GO:0023051,GO:0023052,GO:0023057,GO:0030030,GO:0030154,GO:0030182,GO:0030307,GO:0030326,GO:0030509,GO:0030516,GO:0031175,GO:0031323,GO:0031326,GO:0031344,GO:0031346,GO:0032101,GO:0032103,GO:0032501,GO:0032502,GO:0032535,GO:0032879,GO:0035050,GO:0035107,GO:0035108,GO:0035113,GO:0035239,GO:0035295,GO:0040008,GO:0040011,GO:0040012,GO:0040017,GO:0042074,GO:0042221,GO:0043009,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0045595,GO:0045597,GO:0045664,GO:0045666,GO:0045773,GO:0045879,GO:0045927,GO:0048468,GO:0048513,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048562,GO:0048565,GO:0048568,GO:0048583,GO:0048584,GO:0048585,GO:0048598,GO:0048638,GO:0048639,GO:0048666,GO:0048699,GO:0048704,GO:0048705,GO:0048706,GO:0048729,GO:0048731,GO:0048736,GO:0048841,GO:0048842,GO:0048856,GO:0048869,GO:0048870,GO:0050767,GO:0050769,GO:0050770,GO:0050772,GO:0050789,GO:0050793,GO:0050794,GO:0050896,GO:0050920,GO:0050921,GO:0051094,GO:0051128,GO:0051130,GO:0051171,GO:0051179,GO:0051239,GO:0051240,GO:0051252,GO:0051270,GO:0051272,GO:0051674,GO:0051716,GO:0051960,GO:0051962,GO:0055113,GO:0055123,GO:0060173,GO:0060255,GO:0060284,GO:0060348,GO:0060349,GO:0060429,GO:0060562,GO:0060971,GO:0060972,GO:0060976,GO:0061371,GO:0061387,GO:0061564,GO:0065007,GO:0065008,GO:0070848,GO:0070887,GO:0071310,GO:0071363,GO:0071495,GO:0071772,GO:0071773,GO:0071840,GO:0071907,GO:0072358,GO:0072359,GO:0080090,GO:0090066,GO:0090504,GO:0097094,GO:0097155,GO:0106030,GO:0120035,GO:0120036,GO:1902667,GO:1902669,GO:1903506,GO:1904888,GO:2000026,GO:2000112,GO:2001141 - 0.0000000001014 76.0
PYH3_k127_1608754_4 PFAM Fibronectin type III domain - - - 0.000003267 62.0
PYH3_k127_1664870_0 DeoC/LacD family aldolase K08321,K11645 GO:0003674,GO:0003824,GO:0016740,GO:0016746,GO:0016747 2.3.1.245,4.1.2.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002917 374.0
PYH3_k127_1664870_1 Alcohol dehydrogenase GroES-like domain K00008 - 1.1.1.14 0.00000005806 58.0
PYH3_k127_1664870_2 - - - - 0.0001453 51.0
PYH3_k127_1691055_0 Belongs to the ABC transporter superfamily K02031,K15583 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001379 357.0
PYH3_k127_1691055_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004579 333.0
PYH3_k127_1691055_2 ABC-type dipeptide transport system periplasmic component K02035 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000003294 279.0
PYH3_k127_1691055_3 PFAM binding-protein-dependent transport systems inner membrane component K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000002309 241.0
PYH3_k127_1691055_4 Belongs to the ABC transporter superfamily K02032,K10823 - - 0.0000000000000000000004291 111.0
PYH3_k127_1729713_0 Bifunctional purine biosynthesis protein PurH K00602 - 2.1.2.3,3.5.4.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009462 507.0
PYH3_k127_1729713_1 Methylenetetrahydrofolate reductase K00297 - 1.5.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001486 308.0
PYH3_k127_1729713_2 Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate K11175 - 2.1.2.2 0.0000000000000000000000000000000000000000000000000000000000000000000001287 247.0
PYH3_k127_1729713_3 Domain present in phytochromes and cGMP-specific phosphodiesterases. K08968 - 1.8.4.14 0.00000000000000000005928 96.0
PYH3_k127_1759519_0 TPR Domain containing protein - - - 0.00000000000000000000000000000000007011 140.0
PYH3_k127_1759519_1 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.0000000000000000000000000428 126.0
PYH3_k127_1759519_2 TIGRFAM RHS repeat-associated core domain - - - 0.0000000009323 72.0
PYH3_k127_1785445_0 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001319 439.0
PYH3_k127_1814805_0 Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides K03601 - 3.1.11.6 0.00000000000000000000000000000000000000000000000000003379 195.0
PYH3_k127_1814805_1 Clostripain family - - - 0.00000000000000000000000000000000000000000000000000008957 209.0
PYH3_k127_1814805_2 Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) K00762 - 2.4.2.10 0.0000000000000000000000000000000002701 135.0
PYH3_k127_1819776_0 PFAM ABC-2 type transporter K01992 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000004664 269.0
PYH3_k127_1819776_1 SMART Elongator protein 3 MiaB NifB - - - 0.0000000000000000000000000000000000000000000000000000000000000000003892 250.0
PYH3_k127_1819776_2 TIGRFAM daunorubicin resistance ABC transporter ATPase subunit K01990 - - 0.00000000000001956 74.0
PYH3_k127_1819776_3 aminopeptidase activity K19689 - - 0.0000001957 63.0
PYH3_k127_1819776_4 SCP-2 sterol transfer family - - - 0.00002414 55.0
PYH3_k127_1822642_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004212 496.0
PYH3_k127_1822642_1 RNase_H superfamily K07502 - - 0.0000000000000000000000000000000000000000000000000000000000000000003101 242.0
PYH3_k127_1822642_2 PFAM MazG nucleotide pyrophosphohydrolase domain - - - 0.000000000000000000000000001783 117.0
PYH3_k127_1822642_3 Pfam:KaiC - - - 0.0000004238 58.0
PYH3_k127_186407_0 SMART Elongator protein 3 MiaB NifB - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001726 310.0
PYH3_k127_186407_1 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000002116 244.0
PYH3_k127_186407_2 Sugar-specific transcriptional regulator TrmB - - - 0.0007466 49.0
PYH3_k127_1875047_0 Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome K03234 - - 0.0 1045.0
PYH3_k127_1875047_1 pyruvate flavodoxin ferredoxin oxidoreductase K00174 - 1.2.7.11,1.2.7.3 1.368e-227 724.0
PYH3_k127_1875047_10 FG-GAP repeat - - - 0.000000000000000000005611 111.0
PYH3_k127_1875047_11 Fibronectin type III domain - - - 0.000000000000000001162 101.0
PYH3_k127_1875047_12 - K00960 - 2.7.7.6 0.0000000000000003431 79.0
PYH3_k127_1875047_13 Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P) K01803 - 5.3.1.1 0.0000000000002958 74.0
PYH3_k127_1875047_14 Esterase PHB depolymerase - - - 0.000004169 60.0
PYH3_k127_1875047_15 Putative Ig domain - - - 0.0001638 56.0
PYH3_k127_1875047_16 Outer membrane protein, OmpA MotB, C-terminal - - - 0.0003735 55.0
PYH3_k127_1875047_2 This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis K03231 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 2.346e-204 642.0
PYH3_k127_1875047_3 Catalyzes two subsequent steps in gluconeogenesis the aldol condensation of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (GA3P) to fructose-1,6-bisphosphate (FBP), and the dephosphorylation of FBP to fructose-6-phosphate (F6P) K01622 - 3.1.3.11,4.1.2.13 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008866 519.0
PYH3_k127_1875047_4 Pyruvate ferredoxin oxidoreductase beta subunit C terminal K00175 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003989 431.0
PYH3_k127_1875047_5 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center K02992 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003729,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000002667 227.0
PYH3_k127_1875047_6 Calcineurin-like phosphoesterase K06953 - - 0.000000000000000000000000000000000000000000000000000007936 203.0
PYH3_k127_1875047_7 Involved in the binding of tRNA to the ribosomes K02946 - - 0.000000000000000000000000000000000000000000000001149 175.0
PYH3_k127_1875047_8 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000000000000003732 129.0
PYH3_k127_1875047_9 Peptidase C13 family - - - 0.00000000000000000000004759 116.0
PYH3_k127_1913077_0 Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate K00940 - 2.7.4.6 0.00000000000000000000000000000000000000000000000000000000004505 209.0
PYH3_k127_1913077_1 Belongs to the eukaryotic ribosomal protein eS28 family K02979 GO:0000028,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1990904 - 0.0000000000000000000003797 97.0
PYH3_k127_1913077_2 binds to the 23S rRNA K02896 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1902626,GO:1990904 - 0.00000000000000000003749 98.0
PYH3_k127_1913077_3 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000001871 89.0
PYH3_k127_1913077_4 TIGRFAM haloacid dehalogenase superfamily, subfamily IA, variant 3 with third motif having DD or ED - - - 0.00000203 56.0
PYH3_k127_194258_0 Belongs to the glyceraldehyde-3-phosphate dehydrogenase family K00150 - 1.2.1.59 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001101 404.0
PYH3_k127_194258_1 PFAM homoserine dehydrogenase K00003,K12524 - 1.1.1.3,2.7.2.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000001106 287.0
PYH3_k127_194258_2 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000007486 114.0
PYH3_k127_1964070_0 Metal dependent phosphohydrolases with conserved 'HD' motif. K06885 GO:0003674,GO:0003824,GO:0006139,GO:0006163,GO:0006195,GO:0006203,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008832,GO:0009056,GO:0009058,GO:0009117,GO:0009141,GO:0009143,GO:0009144,GO:0009146,GO:0009151,GO:0009155,GO:0009166,GO:0009200,GO:0009204,GO:0009215,GO:0009217,GO:0009262,GO:0009264,GO:0009394,GO:0009987,GO:0016787,GO:0016788,GO:0016793,GO:0018130,GO:0019438,GO:0019439,GO:0019637,GO:0019692,GO:0034404,GO:0034641,GO:0034654,GO:0034655,GO:0042578,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044270,GO:0044271,GO:0044281,GO:0044283,GO:0046070,GO:0046386,GO:0046434,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901135,GO:1901136,GO:1901292,GO:1901360,GO:1901361,GO:1901362,GO:1901564,GO:1901565,GO:1901575,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002022 367.0
PYH3_k127_1964070_1 Binding-protein-dependent transport system inner membrane component K02033 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006969 319.0
PYH3_k127_1964070_2 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000008189 301.0
PYH3_k127_1964070_3 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002967 282.0
PYH3_k127_1964070_4 Oligopeptide/dipeptide transporter, C-terminal region K02031,K15583 - - 0.00000000000000000000000005126 110.0
PYH3_k127_1964070_5 Peptidase family M28 - - - 0.00005449 52.0
PYH3_k127_1973260_0 PFAM fumarylacetoacetate (FAA) hydrolase - - - 0.000000000000000000000000000000000000000000000000000000000502 224.0
PYH3_k127_1973260_1 Belongs to the PEP-utilizing enzyme family K01006 - 2.7.9.1 0.00000000000000000000000000000000000000000000000000000008842 196.0
PYH3_k127_1973260_2 AAA-like domain K06915 - - 0.00000000000000000000000000000000000000000000003942 179.0
PYH3_k127_1973260_3 Thymidylate kinase K00943 GO:0003674,GO:0003824,GO:0004798,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006227,GO:0006233,GO:0006235,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009041,GO:0009058,GO:0009117,GO:0009123,GO:0009132,GO:0009133,GO:0009138,GO:0009139,GO:0009141,GO:0009142,GO:0009147,GO:0009148,GO:0009165,GO:0009186,GO:0009189,GO:0009196,GO:0009197,GO:0009200,GO:0009202,GO:0009211,GO:0009212,GO:0009219,GO:0009221,GO:0009262,GO:0009263,GO:0009265,GO:0009394,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016776,GO:0018130,GO:0019205,GO:0019438,GO:0019637,GO:0019692,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046072,GO:0046075,GO:0046077,GO:0046385,GO:0046483,GO:0046940,GO:0050145,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.7.4.9 0.000000000000000000000000000000000000000005415 162.0
PYH3_k127_1973260_4 Membrane - - - 0.00000000000000000000000000000009318 134.0
PYH3_k127_1977748_0 Catalyzes the reversible interconversion of serine and glycine with a modified folate serving as the one-carbon carrier. Also exhibits a pteridine-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism K00600 - 2.1.2.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001615 543.0
PYH3_k127_1977748_1 Catalyzes the formation of S-adenosylmethionine from methionine and ATP K00789 - 2.5.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005204 497.0
PYH3_k127_1977748_2 - - - - 0.00000004959 61.0
PYH3_k127_2007435_0 Peptidase family M50 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000009474 302.0
PYH3_k127_2007435_1 VIT family - - - 0.000000000000000000000001023 114.0
PYH3_k127_2007435_2 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 - 6.1.1.7 0.0000000000000005878 83.0
PYH3_k127_2007435_3 Pfam:Methyltransf_26 K07446 GO:0000049,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004809,GO:0005488,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008175,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0140098,GO:0140101,GO:1901360,GO:1901363 2.1.1.213 0.0002298 44.0
PYH3_k127_2027005_0 Pyridoxal-phosphate dependent enzyme K01733 - 4.2.3.1 0.0000000000000000000000000000000000000000000000000086 186.0
PYH3_k127_2027005_1 PFAM SMP-30 Gluconolaconase - - - 0.000000000000000000000000000000000000003355 169.0
PYH3_k127_2027005_2 PFAM SMP-30 Gluconolaconase - - - 0.0000000000000000000178 104.0
PYH3_k127_2027005_3 Glycosyl hydrolases family 43 - - - 0.0000000136 69.0
PYH3_k127_2032169_0 biosynthesis protein QueC K06920 - 6.3.4.20 0.0000000000000000000000000000000000000000000000001921 187.0
PYH3_k127_2032169_1 Ferric reductase NAD binding domain - - - 0.00000000000000000000000000000000000000000001019 171.0
PYH3_k127_2032169_2 6-pyruvoyl tetrahydropterin synthase K01737 - 4.1.2.50,4.2.3.12 0.0000000000000000000000000000000000000000005236 159.0
PYH3_k127_2032169_3 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases K05710 - - 0.0000000000000000002375 100.0
PYH3_k127_2032169_4 KR domain K00059 - 1.1.1.100 0.000000000000000201 79.0
PYH3_k127_2032169_5 PFAM Cupin 2 conserved barrel domain protein - - - 0.00000000000001265 78.0
PYH3_k127_2036299_0 Carbon-nitrogen hydrolase K18540 - 3.5.1.100 0.0000000000000000000000000000000000000000000000000000004094 208.0
PYH3_k127_2036299_1 Multifunctional RNA-binding protein that recognizes the K-turn motif in ribosomal RNA, the RNA component of RNase P, box H ACA, box C D and box C' D' sRNAs K02936 GO:0000470,GO:0000966,GO:0001682,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006399,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0097159,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000001179 71.0
PYH3_k127_2056899_0 Possible Fer4-like domain in RNase L inhibitor, RLI K06174 - - 8.173e-226 718.0
PYH3_k127_2056899_1 Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily K01464,K01465,K01466 GO:0003674,GO:0003824,GO:0004038,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006144,GO:0006145,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009112,GO:0009987,GO:0016787,GO:0016810,GO:0016812,GO:0019439,GO:0034641,GO:0044237,GO:0044238,GO:0044248,GO:0044270,GO:0044281,GO:0044424,GO:0044464,GO:0046113,GO:0046483,GO:0046700,GO:0055086,GO:0071704,GO:0072521,GO:0072523,GO:1901360,GO:1901361,GO:1901564,GO:1901565,GO:1901575 3.5.2.2,3.5.2.3,3.5.2.5 0.0000000000000000000000000000000000000000000000000001062 191.0
PYH3_k127_2056899_2 PFAM SNARE associated Golgi protein - - - 0.000000000000000000000000000000000000000003847 162.0
PYH3_k127_2056899_3 Acetyltransferase (GNAT) domain - - - 0.000000000000000001214 92.0
PYH3_k127_2128115_0 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.000000000000000000000000000000000000000000000153 178.0
PYH3_k127_2128115_1 COG1502 Phosphatidylserine phosphatidylglycerophosphate cardiolipi n synthases and related enzymes - - - 0.00000000000000000000000000000000000009204 154.0
PYH3_k127_2128115_2 COG3291 FOG PKD repeat - - - 0.0000003691 61.0
PYH3_k127_2157620_0 part of an ABC transporter complex. Responsible for energy coupling to the transport system K02006 - - 0.00000000000000000000000000000000000000000000000000000000000000002073 243.0
PYH3_k127_2157620_1 PFAM cobalamin (vitamin B12) biosynthesis CbiM protein K02007 - - 0.0000000000000000000000000000000000000000004365 166.0
PYH3_k127_2157620_2 Patch-forming domain C2 of tRNA-guanine transglycosylase K07557 GO:0002927,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.6.1.97 0.0000000000000000000000003069 110.0
PYH3_k127_2157620_3 cobalt ABC transporter, inner membrane subunit CbiQ K02008 - - 0.0000000000003345 79.0
PYH3_k127_2157620_4 - - - - 0.000004075 57.0
PYH3_k127_21788_0 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000933 509.0
PYH3_k127_21788_1 Belongs to the cysteine synthase cystathionine beta- synthase family K01738 - 2.5.1.47 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003739 344.0
PYH3_k127_21788_2 Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL K01952 - 6.3.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004264 327.0
PYH3_k127_21788_3 Catalyzes the CTP-dependent phosphorylation of riboflavin (vitamin B2) to form flavin mononucleotide (FMN) K07732 - 2.7.1.161 0.000000000000000000000000000000000000000000000000000000000009486 216.0
PYH3_k127_21788_4 IgGFc binding protein - - - 0.000000000000000000000000000000000000000000000000000002901 220.0
PYH3_k127_21788_5 - - - - 0.0000000000000000000000000001222 130.0
PYH3_k127_21788_6 transferase activity, transferring glycosyl groups K20276 - - 0.000000000000000000005087 109.0
PYH3_k127_21788_7 Fcf1 K07158 - - 0.00000000000000000007974 94.0
PYH3_k127_2189984_0 ATPase associated with various cellular activities K03924 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 407.0
PYH3_k127_2189984_1 Domain of unknown function (DUF4129) - - - 0.0000000000001316 74.0
PYH3_k127_2189984_2 conserved protein (some members contain a von Willebrand factor type A (vWA) domain) - - - 0.00001739 51.0
PYH3_k127_2217424_0 Cell division protein 48 (CDC48) domain 2 K13525 - - 1.141e-299 935.0
PYH3_k127_2217424_1 Heat shock 70 kDa protein K04043 - - 2.194e-232 734.0
PYH3_k127_2217424_2 ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins K03686 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001686 357.0
PYH3_k127_2217424_3 - - - - 0.0000000000000000000000000000000002505 141.0
PYH3_k127_2217424_4 COG1664 Integral membrane protein CcmA involved in cell shape determination - - - 0.000000000000000000000000000000001655 143.0
PYH3_k127_2217424_5 PRC-barrel domain - - - 0.00000000000000000000000002844 110.0
PYH3_k127_2217424_6 Band 7 protein K07192 - - 0.000000000000000000000001116 113.0
PYH3_k127_2217424_7 Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ K03687 - - 0.00000000000000000000007858 103.0
PYH3_k127_2217424_8 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000007214 83.0
PYH3_k127_2226567_0 DNA polymerase elongation subunit (Family B) K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001294 419.0
PYH3_k127_2226567_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005614 302.0
PYH3_k127_2226567_2 COGs COG4328 conserved - - - 0.000000000000000000000000000000000000000000000000000501 196.0
PYH3_k127_2226567_3 - - - - 0.000000000003997 70.0
PYH3_k127_2226567_4 Possibly the antitoxin component of a - - - 0.000000004153 61.0
PYH3_k127_2226567_5 acid acetyltransferase K06718 GO:0003674,GO:0003824,GO:0006464,GO:0006473,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016740,GO:0016746,GO:0016747,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0043543,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0071704,GO:1901564 2.3.1.178 0.0000004235 60.0
PYH3_k127_2226567_6 Toxic component of a toxin-antitoxin (TA) module. An RNase K18828 - - 0.000005106 59.0
PYH3_k127_2245989_0 Catalyzes the synthesis of GMP from XMP K01951 - 6.3.5.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001518 359.0
PYH3_k127_2358694_0 DNA-dependent ATPase and 3'-5' DNA helicase that may be involved in repair of stalled replication forks K03726 - - 1.365e-194 630.0
PYH3_k127_2358694_1 COG0491 Zn-dependent hydrolases, including glyoxylases K01069 - 3.1.2.6 0.00000000000000000000000000000000000000000000000000000004561 219.0
PYH3_k127_2358694_2 LemA family K03744 - - 0.00000000000000000000000000000000000623 144.0
PYH3_k127_2358694_3 TPM domain K06872 - - 0.000000000000000000000000000002293 128.0
PYH3_k127_2358694_4 KEOPS complex Cgi121-like subunit K09119 - - 0.0000000000004097 76.0
PYH3_k127_2358694_5 cellulase activity K07019 - - 0.00000000000146 81.0
PYH3_k127_2393239_0 PFAM PEGA domain - - - 0.00000000000000001175 97.0
PYH3_k127_2393239_1 peptidase M36 K01417 - - 0.00001942 57.0
PYH3_k127_2412925_0 PFAM carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001192 297.0
PYH3_k127_2412925_1 PFAM peptidase S45 penicillin amidase K01434 - 3.5.1.11 0.00000000000000000000000000008811 122.0
PYH3_k127_2412925_2 - - - - 0.000001076 56.0
PYH3_k127_2468351_0 PFAM FAD-dependent pyridine nucleotide-disulphide oxidoreductase K17218 - 1.8.5.4 0.0000000000000000000000000000000000000000000000000000001036 199.0
PYH3_k127_2468351_1 DsrE/DsrF/DrsH-like family - - - 0.00000000000000000000000000000000000001514 150.0
PYH3_k127_2468351_2 Sulfurtransferase TusA - - - 0.00000000000000000000000003875 109.0
PYH3_k127_2468351_3 regulatory protein, arsR K07755,K21903 - 2.1.1.137 0.00000000000000002793 85.0
PYH3_k127_2468351_4 Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily - - - 0.000000000004779 71.0
PYH3_k127_2469272_0 Involved in regulation of DNA replication K10725 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000002422 309.0
PYH3_k127_2469272_1 DHHA1 domain K07463 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000006444 286.0
PYH3_k127_2469272_2 Methyltransferase type 11 - - - 0.00000000000000000000000000000000000000000000000000000000000000002656 228.0
PYH3_k127_2469272_3 Ribosomal S13/S15 N-terminal domain K02956 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0019843,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070181,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000002074 178.0
PYH3_k127_2469272_4 Nad-dependent epimerase dehydratase - - - 0.00000000000000000000000000000009732 136.0
PYH3_k127_2469272_5 Conserved repeat domain - - - 0.00000000000000000000000009694 121.0
PYH3_k127_2469272_6 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.000000000000000003815 92.0
PYH3_k127_2469272_7 Serine threonine protein kinase - - - 0.0000001277 65.0
PYH3_k127_2501141_0 Aminotransferase class-III K00823 - 2.6.1.19 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002225 456.0
PYH3_k127_2501141_1 Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis K01689 - 4.2.1.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005486 429.0
PYH3_k127_2501141_10 ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA K06932 - 6.3.4.22 0.0002103 45.0
PYH3_k127_2501141_2 ABC transporter, ATP-binding protein K02028,K17076 - 3.6.3.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001237 311.0
PYH3_k127_2501141_3 Belongs to the universal ribosomal protein uS2 family K02967 GO:0000028,GO:0000447,GO:0000460,GO:0000461,GO:0000462,GO:0000466,GO:0000469,GO:0000478,GO:0000479,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0016070,GO:0016072,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0030490,GO:0031123,GO:0031125,GO:0032991,GO:0034470,GO:0034622,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043628,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001328 282.0
PYH3_k127_2501141_4 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.0000000000000000000000000000000000000000001031 173.0
PYH3_k127_2501141_5 amino acid ABC transporter K02029 - - 0.00000000000000000000000000000002403 137.0
PYH3_k127_2501141_6 Belongs to the bacterial solute-binding protein 3 family K02030 - - 0.000000000000000000000000001641 123.0
PYH3_k127_2501141_7 ABC transporter K02029 - - 0.0000000000000000000000005791 117.0
PYH3_k127_2501141_8 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03055 - 2.7.7.6 0.0000000000000009748 81.0
PYH3_k127_2501141_9 DNA topoisomerase type I activity K03169 - 5.99.1.2 0.0000000000003174 72.0
PYH3_k127_250592_0 Pkd domain containing protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002217 336.0
PYH3_k127_250592_1 S-adenosyl-L-methionine-dependent methyltransferase that catalyzes the trimethylation of the amino group of the modified target histidine residue in translation elongation factor 2 (EF- 2), to form an intermediate called diphthine. The three successive methylation reactions represent the second step of diphthamide biosynthesis K20215 - 2.1.1.98 0.00000000000000000000000000000000000000000000000000000000000000000000000002459 261.0
PYH3_k127_250592_10 self proteolysis - - - 0.00000004261 66.0
PYH3_k127_250592_2 Met-10+ like-protein K15429 GO:0001510,GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008175,GO:0008757,GO:0009019,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016423,GO:0016740,GO:0016741,GO:0030488,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0043414,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360 2.1.1.228 0.0000000000000000000000000000000000000000000000000000000000000000002897 243.0
PYH3_k127_250592_3 dUTPase K01494 - 3.5.4.13 0.0000000000000000000000000000000000000000000009075 173.0
PYH3_k127_250592_4 methyltransferase K03183 - 2.1.1.163,2.1.1.201 0.000000000000000000000000001414 122.0
PYH3_k127_250592_5 PKD domain - - - 0.000000000000000000001326 111.0
PYH3_k127_250592_6 exo-alpha-(2->6)-sialidase activity - - - 0.000000000000000004706 100.0
PYH3_k127_250592_8 HAD-hyrolase-like - - - 0.000000000001239 70.0
PYH3_k127_250592_9 Domain of unknown function (DUF4082) - - - 0.00000000007022 77.0
PYH3_k127_2531819_0 Flotillin K07192 - - 0.000000000000000000000000000000000000001877 164.0
PYH3_k127_2613527_0 PFAM Bile acid sodium symporter K03325 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006187 418.0
PYH3_k127_2613527_1 Superoxide dismutase K00518 - 1.15.1.1 0.0000000000000000000000000000000000000000002167 164.0
PYH3_k127_2613527_2 DGC domain - - - 0.0000000000000000000000000000000001126 142.0
PYH3_k127_2613527_3 The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein K02437 - - 0.0000000000000000000000000000002239 131.0
PYH3_k127_2613527_4 DGC domain - - - 0.00000000000000000000000003207 114.0
PYH3_k127_2613527_5 helix_turn_helix, Arsenical Resistance Operon Repressor K21903 - - 0.0000000000000003027 84.0
PYH3_k127_2613527_6 redox-active disulfide protein 2 - - - 0.00000000000000041 82.0
PYH3_k127_2613527_7 response to oxidative stress K04063 - - 0.000000007952 59.0
PYH3_k127_2613527_8 Signal peptidase, peptidase S26 K03100 - 3.4.21.89 0.0000006513 61.0
PYH3_k127_266768_0 Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source K00820 - 2.6.1.16 1.086e-195 626.0
PYH3_k127_266768_1 EamA-like transporter family - - - 0.0000000005451 71.0
PYH3_k127_266768_2 serine-type endopeptidase activity - - - 0.0000000007199 64.0
PYH3_k127_2681364_0 PFAM Glutamyl glutaminyl-tRNA synthetase, class Ic, catalytic K01886 - 6.1.1.18 6.837e-232 724.0
PYH3_k127_2681364_1 Glycerol-3-phosphate dehydrogenase K00111 - 1.1.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006604 345.0
PYH3_k127_2681364_2 PFAM Diacylglycerol kinase catalytic domain - - - 0.0000000000000000000000000000000000000000000000000000000000000001103 234.0
PYH3_k127_2681364_3 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000000000000003042 229.0
PYH3_k127_2681364_4 Protein of unknown function (DUF981) K08980 - - 0.000000000000000000000000000000000006135 147.0
PYH3_k127_2688573_0 Protein of unknown function (DUF3494) - - - 0.000000000000000003294 99.0
PYH3_k127_2692836_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02322 GO:0003674,GO:0005488,GO:0005515,GO:0042802 2.7.7.7 0.0 1152.0
PYH3_k127_2692836_1 PFAM Aminotransferase class I and II K00812 - 2.6.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007744 426.0
PYH3_k127_2692836_2 Pfam:KaiC - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001383 321.0
PYH3_k127_2692836_3 Protein disulfide isomerase family A, member 5 K01829,K09583 GO:0003674,GO:0003756,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005783,GO:0005788,GO:0005789,GO:0006457,GO:0006950,GO:0006986,GO:0007154,GO:0007165,GO:0008150,GO:0008152,GO:0009987,GO:0010033,GO:0012505,GO:0015036,GO:0015037,GO:0016020,GO:0016491,GO:0016667,GO:0016853,GO:0016860,GO:0016864,GO:0023052,GO:0030968,GO:0031974,GO:0031984,GO:0033554,GO:0034620,GO:0034976,GO:0035966,GO:0035967,GO:0036498,GO:0042175,GO:0042221,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044425,GO:0044432,GO:0044444,GO:0044446,GO:0044464,GO:0050789,GO:0050794,GO:0050896,GO:0051716,GO:0055114,GO:0065007,GO:0070013,GO:0070887,GO:0071310,GO:0098827,GO:0140096 5.3.4.1 0.000000007483 64.0
PYH3_k127_2713712_0 this gene contains a nucleotide ambiguity which may be the result of a sequencing error - - - 0.00000000001711 78.0
PYH3_k127_2713712_1 Periplasmic or secreted lipoprotein - - - 0.0000003503 64.0
PYH3_k127_2798709_0 4-hydroxyphenylacetate 3-hydroxylase C terminal K00483,K14534 - 1.14.14.9,4.2.1.120,5.3.3.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002665 448.0
PYH3_k127_2798709_1 acyl-CoA dehydrogenase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 409.0
PYH3_k127_2798709_2 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000002925 105.0
PYH3_k127_2798709_3 Acetyltransferase (GNAT) domain - - - 0.0002009 53.0
PYH3_k127_2798709_4 Domain of unknown function, E. rectale Gene description (DUF3881) - - - 0.0009045 52.0
PYH3_k127_2799358_0 PFAM Aldehyde dehydrogenase K22187 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005073 546.0
PYH3_k127_2799358_1 1,7-bisphosphate phosphatase - - - 0.0000000000000000000000000000000000001529 158.0
PYH3_k127_2801079_0 Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides K01255,K01259 GO:0001073,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004177,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005739,GO:0006139,GO:0006259,GO:0006276,GO:0006310,GO:0006351,GO:0006355,GO:0006508,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0008238,GO:0009056,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016787,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0019538,GO:0019904,GO:0031323,GO:0031326,GO:0031554,GO:0031564,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0042150,GO:0043170,GO:0043171,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043244,GO:0043603,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0050789,GO:0050794,GO:0051128,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0070011,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:0097718,GO:0140096,GO:0140110,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901576,GO:1903506,GO:2000112,GO:2001141 3.4.11.1,3.4.11.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002336 449.0
PYH3_k127_2801079_1 Winged helix-turn-helix DNA-binding - - - 0.00000005352 65.0
PYH3_k127_2807033_0 Belongs to the MCM family K10726 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009152 467.0
PYH3_k127_2807033_1 NMD3 family K07562 - - 0.00000000000000000000000000000000000004886 156.0
PYH3_k127_2807033_2 Protein of unknown function (DUF424) K09148 - - 0.00000000000000000682 87.0
PYH3_k127_2816735_0 Domain of unknown function (DUF1611_N) Rossmann-like domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005589 336.0
PYH3_k127_2816735_1 Pfam:DUF137 K09722 - 6.3.2.36 0.000000000000000000000000000000000000000000000000000000000000000000000000000007083 265.0
PYH3_k127_2863190_0 Could be responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs K11131 GO:0000154,GO:0000495,GO:0001522,GO:0003674,GO:0003824,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009451,GO:0009982,GO:0009987,GO:0010467,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016556,GO:0016853,GO:0016866,GO:0022613,GO:0031118,GO:0031120,GO:0031123,GO:0031126,GO:0033979,GO:0034470,GO:0034641,GO:0034660,GO:0034964,GO:0040031,GO:0042254,GO:0043144,GO:0043170,GO:0043412,GO:0043628,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990481 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003423 346.0
PYH3_k127_2863190_1 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site K12589 GO:0000177,GO:0000178,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0017091,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005216 320.0
PYH3_k127_2863190_2 Sugar isomerase (SIS) K15916 - 5.3.1.8,5.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000001419 234.0
PYH3_k127_2863190_3 Belongs to the cytidylate kinase family. Type 2 subfamily K00945 - 2.7.4.25 0.000000000000000000000000000000000000003969 152.0
PYH3_k127_2863190_4 Integral membrane protein DUF106 - - - 0.000000000000000000000000003599 121.0
PYH3_k127_2863190_5 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04798 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006457,GO:0006996,GO:0007010,GO:0008150,GO:0009987,GO:0016043,GO:0016272,GO:0022607,GO:0032991,GO:0034622,GO:0043933,GO:0044085,GO:0044424,GO:0044464,GO:0051087,GO:0051131,GO:0065003,GO:0071840 - 0.000000000000000000008923 99.0
PYH3_k127_2863190_6 binds to the 23S rRNA K02921 - - 0.0000000000000000003185 100.0
PYH3_k127_2863190_7 Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate K02858 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0008686,GO:0009058,GO:0009110,GO:0009231,GO:0009987,GO:0016829,GO:0016830,GO:0017144,GO:0018130,GO:0034641,GO:0042364,GO:0042726,GO:0042727,GO:0044237,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 4.1.99.12 0.00000000000000005579 93.0
PYH3_k127_2863190_8 DNA directed RNA polymerase, 7 kDa subunit K03059 - 2.7.7.6 0.00000000007056 69.0
PYH3_k127_2863190_9 Transcription factor Pcc1 K09741 - - 0.0000002415 58.0
PYH3_k127_2917133_0 - - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008396 325.0
PYH3_k127_2917133_1 PFAM aspartate ornithine carbamoyltransferase carbamoyl-P binding domain K00609 GO:0003674,GO:0003824,GO:0004070,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006220,GO:0006221,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009117,GO:0009165,GO:0009218,GO:0009220,GO:0009259,GO:0009260,GO:0009987,GO:0016740,GO:0016741,GO:0016743,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072527,GO:0072528,GO:0090407,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 2.1.3.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000006837 291.0
PYH3_k127_2917133_2 PFAM Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006483 265.0
PYH3_k127_2917133_3 methyltransferase K13311,K13326,K21335 GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0008150,GO:0008152,GO:0008168,GO:0008757,GO:0009058,GO:0009987,GO:0016740,GO:0016741,GO:0016999,GO:0017000,GO:0017144,GO:0032259,GO:0042802,GO:0042803,GO:0044237,GO:0044249,GO:0046983 2.1.1.234 0.00000000000000000000000000000000000000000000000000000000000003554 224.0
PYH3_k127_2917133_4 PFAM Thioredoxin K03671 - - 0.00000000000000000000000000000000006252 138.0
PYH3_k127_2917133_5 transcriptional regulators - - - 0.00000000000000000005389 94.0
PYH3_k127_3032739_0 Binds directly to 23S rRNA. Probably involved in E site tRNA release K02863 GO:0000470,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001105 272.0
PYH3_k127_3032739_1 Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors K02864 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000005483 265.0
PYH3_k127_3032739_2 Right handed beta helix region - - - 0.00002134 54.0
PYH3_k127_303879_0 Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer) K01613 GO:0005575,GO:0005623,GO:0005886,GO:0016020,GO:0044464,GO:0071944 4.1.1.65 0.00000000000000000000000000000000000000002429 160.0
PYH3_k127_303879_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17103 - 2.7.8.8 0.0000000000000003313 90.0
PYH3_k127_303879_2 Glycosyl transferase family 41 - - - 0.00000293 54.0
PYH3_k127_3048781_0 Belongs to the alpha-IPM synthase homocitrate synthase family K01649 - 2.3.3.13 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000148 344.0
PYH3_k127_3048781_1 FHA domain containing protein - - - 0.0000000003461 73.0
PYH3_k127_3055536_0 Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication K04802 GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006272,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0022616,GO:0030234,GO:0030337,GO:0032991,GO:0034641,GO:0034645,GO:0042802,GO:0043170,GO:0043626,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0044796,GO:0046483,GO:0050790,GO:0065007,GO:0065009,GO:0071704,GO:0090304,GO:0098772,GO:1901360,GO:1901576 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000008728 270.0
PYH3_k127_3055536_1 Phosphate transporter family K03306 - - 0.00000000000000000000000000000000004559 136.0
PYH3_k127_3055536_2 Belongs to the archaeal rpoM eukaryotic RPA12 RPB9 RPC11 RNA polymerase family K03057 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006355,GO:0008150,GO:0008270,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0030880,GO:0031323,GO:0031326,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0061695,GO:0065007,GO:0080090,GO:1902494,GO:1903506,GO:1990234,GO:2000112,GO:2001141 - 0.00000000000000000000000000005096 119.0
PYH3_k127_3136398_0 Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate K01491 - 1.5.1.5,3.5.4.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000218 353.0
PYH3_k127_3149822_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 518.0
PYH3_k127_3149822_1 PFAM Aminotransferase, class I - - - 0.00000000000000000000000000000000000000000000003148 175.0
PYH3_k127_3149822_2 - - - - 0.0000000000000000000000000000000000004211 162.0
PYH3_k127_3149822_3 COG0685 5,10-methylenetetrahydrofolate reductase - - - 0.00000000000000000000000000000006195 137.0
PYH3_k127_3177987_0 B3/4 domain - - - 0.000000000000000000000000000000000000000000000000000000001119 208.0
PYH3_k127_3177987_1 ABC-2 family transporter protein K01992,K19341 - - 0.0000000000000000000000000000000009385 139.0
PYH3_k127_3180316_0 DNA polymerase type-B family K02319 - 2.7.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002149 476.0
PYH3_k127_3180316_1 pfkB family carbohydrate kinase - - - 0.00000002362 63.0
PYH3_k127_3188601_0 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001815 331.0
PYH3_k127_3188601_1 COG0624, acetylornithine deacetylase succinyl-diaminopimelate desuccinylase and related deacylases K01439 - 3.5.1.18 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001505 295.0
PYH3_k127_3209493_0 The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor K00283 - 1.4.4.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002414 578.0
PYH3_k127_3209493_1 Domain of unknown function (DUF373) K08975 - - 0.00000000000000000000000000000000000000000000000000000000000001498 229.0
PYH3_k127_3209493_2 Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6- hydroxymethyl-7,8-dihydropterin diphosphate (6-HMDP) K07142 - 2.7.6.3 0.0000000000000000000000000000000000000000000000000000003485 200.0
PYH3_k127_3209493_3 Psort location Cytoplasmic, score 8.87 - - - 0.0002103 45.0
PYH3_k127_3235018_0 Belongs to the CarB family K01955 GO:0000050,GO:0003674,GO:0003824,GO:0004087,GO:0004088,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006520,GO:0006525,GO:0006526,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009064,GO:0009084,GO:0009987,GO:0016053,GO:0016874,GO:0016879,GO:0016884,GO:0019627,GO:0019752,GO:0034641,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0071704,GO:0071941,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.5.5 8.689e-246 772.0
PYH3_k127_3235018_1 Cation transporter/ATPase, N-terminus K01537 - 3.6.3.8 6.77e-241 773.0
PYH3_k127_3235018_10 COG1670 acetyltransferases, including N-acetylases of ribosomal proteins - - - 0.00000000001301 73.0
PYH3_k127_3235018_2 Belongs to the CarA family K01956 - 6.3.5.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001214 368.0
PYH3_k127_3235018_3 Catalyzes the conversion of 3'-phosphate to a 2',3'- cyclic phosphodiester at the end of RNA. The mechanism of action of the enzyme occurs in 3 steps (A) adenylation of the enzyme by ATP K01974 - 6.5.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001978 328.0
PYH3_k127_3235018_4 PAC2 family K06869 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000004234 263.0
PYH3_k127_3235018_5 RibD C-terminal domain K14654 GO:0000166,GO:0003674,GO:0003824,GO:0005488,GO:0005515,GO:0006139,GO:0006725,GO:0006766,GO:0006767,GO:0006771,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009110,GO:0009231,GO:0009451,GO:0009987,GO:0016070,GO:0016491,GO:0016614,GO:0016616,GO:0017144,GO:0018130,GO:0034641,GO:0036094,GO:0042364,GO:0042726,GO:0042727,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046483,GO:0046983,GO:0048037,GO:0050661,GO:0050662,GO:0051287,GO:0055114,GO:0071704,GO:0090304,GO:0097159,GO:1901265,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 1.1.1.302 0.000000000000000000000000000000000000000000000000000000005471 213.0
PYH3_k127_3235018_6 Sodium/hydrogen exchanger family K03455 - - 0.00000000000000000000000000000000000000003771 177.0
PYH3_k127_3235018_7 Mut7-C RNAse domain K09122 - - 0.0000000000000000000000000000008176 135.0
PYH3_k127_3235018_8 Acetyltransferase (GNAT) domain - - - 0.0000000000000000000000000501 121.0
PYH3_k127_3235018_9 redox protein, regulator of disulfide bond formation K07397 - - 0.0000000000000000001541 102.0
PYH3_k127_3291929_0 Belongs to the eukaryotic ribosomal protein eL15 family K02877 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001145 275.0
PYH3_k127_3295796_0 Serine hydroxymethyltransferase K00600 - 2.1.2.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007417 302.0
PYH3_k127_3295796_1 UBA THIF-type NAD FAD binding protein K03148,K21029 - 2.7.7.73,2.7.7.80 0.0000000000000000000000000000000000000249 148.0
PYH3_k127_3343291_0 Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source K01916 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009435,GO:0009987,GO:0018130,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0019674,GO:0034641,GO:0034654,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046496,GO:0051186,GO:0051188,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 6.3.1.5 0.000000000000000000000000000000000000000000000000000000000000000005005 244.0
PYH3_k127_3343291_1 Protein of unknown function (DUF1349) - - - 0.00000000000000000000000000000000000000000000000000000000000000001611 252.0
PYH3_k127_3343291_2 Transcriptional regulator K07722 GO:0003674,GO:0003676,GO:0003677,GO:0005488,GO:0006355,GO:0008150,GO:0009889,GO:0010468,GO:0010556,GO:0019219,GO:0019222,GO:0031323,GO:0031326,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0080090,GO:0097159,GO:1901363,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000278 81.0
PYH3_k127_3343291_3 protein conserved in archaea - - - 0.00000000001082 79.0
PYH3_k127_3343291_4 ZIP Zinc transporter K07238 - - 0.00000000489 63.0
PYH3_k127_3370698_0 SMART Integrin alpha beta-propellor repeat protein - - - 0.000000000000000000000000000000000002007 159.0
PYH3_k127_3386204_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 4.444e-226 721.0
PYH3_k127_3386204_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K17686 - 3.6.3.54 0.0000000000000002815 78.0
PYH3_k127_3386204_2 Predicted membrane protein (DUF2085) - - - 0.0000000000003996 80.0
PYH3_k127_3386204_3 helix_turn_helix ASNC type K03719 - - 0.000000000009821 70.0
PYH3_k127_3386204_4 ribosomal small subunit binding - - - 0.000008902 55.0
PYH3_k127_3413796_0 TIGRFAM small GTP-binding protein K06944 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 431.0
PYH3_k127_3413796_1 Belongs to the carbamate kinase family K00926 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006525,GO:0006527,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008804,GO:0009056,GO:0009063,GO:0009064,GO:0009065,GO:0009987,GO:0016054,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016774,GO:0019546,GO:0019752,GO:0043436,GO:0044237,GO:0044238,GO:0044248,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046395,GO:0071704,GO:1901564,GO:1901565,GO:1901575,GO:1901605,GO:1901606 2.7.2.2 0.0000000000000000000000000000008348 124.0
PYH3_k127_3413796_2 VKc - - - 0.0000000000004097 76.0
PYH3_k127_3413796_3 Glutathione peroxidase K02199 - - 0.0000000000005342 78.0
PYH3_k127_3413796_4 amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner K01873 GO:0003674,GO:0003824,GO:0004812,GO:0004832,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.9 0.00000002245 57.0
PYH3_k127_3420444_0 ArsR transcriptional regulator - - - 0.0000000000000000000000000000000000000000000000000000000029 205.0
PYH3_k127_3420444_1 - - - - 0.0002801 46.0
PYH3_k127_3420444_2 OB-fold nucleic acid binding domain - - - 0.0003575 48.0
PYH3_k127_3420960_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01883 - 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001538 409.0
PYH3_k127_3424742_0 Aminotransferase class I and II K00812 - 2.6.1.1 0.0000000000000000003319 89.0
PYH3_k127_3446106_0 This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits K02931 - - 0.0000000000000000000000000000000000000000000000000000000000000894 222.0
PYH3_k127_3446106_1 Ribosomal family S4e K02987 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000541 219.0
PYH3_k127_3446106_2 Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome K02874 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0019843,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0070180,GO:0097159,GO:1901363,GO:1990904 - 0.00000000000000000000000000000000000000000000000000006072 197.0
PYH3_k127_3446106_3 One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit K02994 - - 0.0000000000000000000000000000000000000000000000001624 184.0
PYH3_k127_3446106_4 One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA K02961 GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0019538,GO:0022626,GO:0022627,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000483 141.0
PYH3_k127_3446106_5 Located at the polypeptide exit tunnel on the outside of the subunit K02895 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022613,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0042254,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000002689 103.0
PYH3_k127_3446106_6 ribosomal protein S14 K02954 - - 0.0000000000000002263 87.0
PYH3_k127_3446106_7 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03538 GO:0000172,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005732,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030677,GO:0032991,GO:0033204,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.000000000000000368 87.0
PYH3_k127_3446106_8 Belongs to the universal ribosomal protein uL29 family K02904 - - 0.000000000000004307 77.0
PYH3_k127_345460_0 PFAM Beta propeller domain K14475 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002892 430.0
PYH3_k127_345460_1 resolution of meiotic recombination intermediates - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004874 356.0
PYH3_k127_345460_2 Creatinine amidohydrolase K01470 - 3.5.2.10 0.000000000000000000000000000000000000003553 153.0
PYH3_k127_345460_3 Diphthamide synthase K06927 - 6.3.1.14 0.000000000000000005258 87.0
PYH3_k127_3489776_0 Catalyzes the ATP- and formate-dependent formylation of 5-aminoimidazole-4-carboxamide-1-beta-d-ribofuranosyl 5'- monophosphate (AICAR) to 5-formaminoimidazole-4-carboxamide-1- beta-d-ribofuranosyl 5'-monophosphate (FAICAR) in the absence of folates K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006498 464.0
PYH3_k127_3489776_1 Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr) K01868 GO:0003674,GO:0003824,GO:0004812,GO:0004829,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006435,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002126 451.0
PYH3_k127_3489776_2 Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives K00796 - 2.5.1.15 0.000000000000000000000000000000000000000000000000000000000000000000000000000000004579 282.0
PYH3_k127_3489776_3 TIGRFAM ribosomal-protein-alanine acetyltransferase K03789 - 2.3.1.128 0.000002568 59.0
PYH3_k127_3512476_0 SHS2 domain found in N terminus of Rpb7p/Rpc25p/MJ0397 K03049 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.000000000000000000000000000000000000000000000000000000000000001489 225.0
PYH3_k127_3512476_1 Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force K15987 - 3.6.1.1 0.000000000000000000000000000000000008244 138.0
PYH3_k127_3512476_2 Belongs to the UPF0218 family K09735 - - 0.00000000000000000000002092 107.0
PYH3_k127_3512476_3 Transcription elongation factor Spt4 K03050 - 2.7.7.6 0.00000000000000000005229 92.0
PYH3_k127_3512476_4 Belongs to the eukaryotic ribosomal protein eS24 family K02974 - - 0.000000000000000002164 92.0
PYH3_k127_3512476_5 Belongs to the eukaryotic ribosomal protein eS31 family K02977 - - 0.00000000000000007075 81.0
PYH3_k127_3577227_0 Belongs to the DegT DnrJ EryC1 family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000512 393.0
PYH3_k127_3577227_1 Hexapeptide repeat of succinyl-transferase - - - 0.00000000000000000000000000000000000000000000000000000000000000001113 230.0
PYH3_k127_3577227_2 COGs COG4591 ABC-type transport system involved in lipoprotein release permease component K02004 - - 0.00000000000000000000000005529 114.0
PYH3_k127_3578114_0 ATPases associated with a variety of cellular activities K02003 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001096 273.0
PYH3_k127_3578114_1 MacB-like periplasmic core domain K02004 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000114 275.0
PYH3_k127_3578114_2 Alternative locus ID K03810 - - 0.0000000000000000000002508 100.0
PYH3_k127_3581466_0 Beta-Casp domain K07577 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001688 460.0
PYH3_k127_3581466_1 FAD dependent oxidoreductase - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001571 315.0
PYH3_k127_3581466_2 FAD binding domain - - - 0.00000000000000000000000000000000000000000000000000000000000000002542 238.0
PYH3_k127_3581466_3 Polyprenyl synthetase K02523,K13787 GO:0003674,GO:0003824,GO:0004659,GO:0016740,GO:0016765 2.5.1.1,2.5.1.10,2.5.1.29,2.5.1.90 0.00000000000000000000000000000000000000000000000000000005034 208.0
PYH3_k127_3581466_4 Archaeal transcriptional regulator TrmB - - - 0.000000000000000000000000000000000000000000000008329 176.0
PYH3_k127_3596277_0 COG0531 Amino acid transporters - - - 0.0000000000000000000000000000000004547 147.0
PYH3_k127_3596277_1 Mechanosensitive ion channel - - - 0.000000000000000000002103 108.0
PYH3_k127_3602114_0 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000009048 289.0
PYH3_k127_3602114_1 Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( K02823 - - 0.00000000000000000000000000000000000000000000000000000000000002068 228.0
PYH3_k127_3602114_2 ABC-2 family transporter protein K01992 - - 0.000000000000000000000000000000000008729 145.0
PYH3_k127_3602114_3 Catalyzes the conversion of dihydroorotate to orotate K17828 GO:0003674,GO:0003824,GO:0004152,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006206,GO:0006207,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009112,GO:0009987,GO:0016491,GO:0016627,GO:0016635,GO:0018130,GO:0019856,GO:0034641,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046112,GO:0046483,GO:0055086,GO:0055114,GO:0071704,GO:0072527,GO:0072528,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576 1.3.1.14 0.00000000000000000000000001051 111.0
PYH3_k127_3648075_0 Transport and Golgi organisation 2 - - - 0.0000000000000000000000000221 118.0
PYH3_k127_3648075_1 Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine K07304,K12267 - 1.8.4.11,1.8.4.12 0.0000000000000000000000003117 105.0
PYH3_k127_3648075_2 ubiE/COQ5 methyltransferase family - - - 0.00000009268 62.0
PYH3_k127_3665913_0 Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) K06920 - 6.3.4.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000006296 286.0
PYH3_k127_3665913_1 PFAM Diphthamide synthesis DPH2 protein K07561 - 2.5.1.108 0.000000000000000000000000000000000000000000000000000000000000000000000000000001516 274.0
PYH3_k127_3665913_2 Belongs to the universal ribosomal protein uL16 family K02866 - - 0.0000000000000000000000000000000000000000000000000001393 190.0
PYH3_k127_3665913_3 Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7- carboxy-7-deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds K10026 - 4.3.99.3 0.0000000000000000000000000000000000000000000006373 175.0
PYH3_k127_3665913_4 M42 glutamyl aminopeptidase - - - 0.000000000000000000000000000000000000001854 160.0
PYH3_k127_3665913_5 hydrolase (HAD superfamily) K07025 - - 0.0000000000000000000000000000002762 133.0
PYH3_k127_3665913_6 COG3407 Mevalonate pyrophosphate decarboxylase K17942 - 4.1.1.99 0.0000000000000000000000000001504 117.0
PYH3_k127_3665913_7 Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently - - - 0.0000000000000000000000000002584 119.0
PYH3_k127_3819225_0 endonuclease III - - - 0.0000000000000000000000000000000000000000000000000000462 205.0
PYH3_k127_3819225_1 HAD-hyrolase-like K01560 - 3.8.1.2 0.00000000000000000000003205 108.0
PYH3_k127_3819225_2 Roadblock LC7 family protein K07131 - - 0.0000000000009715 73.0
PYH3_k127_3819225_3 Acid phosphatase homologues K19302 - 3.6.1.27 0.000000000004388 79.0
PYH3_k127_3819225_4 aminopeptidase activity - - - 0.000000000008764 70.0
PYH3_k127_3819225_5 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.0000000002832 65.0
PYH3_k127_3822980_0 helix_turn_helix, Arsenical Resistance Operon Repressor K07721 - - 0.0000000000000000001439 93.0
PYH3_k127_3822980_1 PFAM Circadian clock protein KaiC - - - 0.000000002164 67.0
PYH3_k127_3868471_0 amine dehydrogenase activity - - - 0.000000000004108 81.0
PYH3_k127_3868471_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.00001548 59.0
PYH3_k127_3868929_0 GyrI-like small molecule binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000003024 226.0
PYH3_k127_3868929_1 Belongs to the ribulose-phosphate 3-epimerase family K01783 GO:0003674,GO:0003824,GO:0004750,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009056,GO:0009117,GO:0009987,GO:0016052,GO:0016853,GO:0016854,GO:0016857,GO:0019321,GO:0019323,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044262,GO:0044281,GO:0044282,GO:0044424,GO:0044444,GO:0044464,GO:0046365,GO:0046483,GO:0046496,GO:0046872,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564,GO:1901575 5.1.3.1 0.000000000000000000000000000000000000000000000000000000000000001956 224.0
PYH3_k127_3868929_2 COG0454 Histone acetyltransferase HPA2 and related acetyltransferases K22441 - 2.3.1.57 0.0004356 53.0
PYH3_k127_387454_0 Subtilase family - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003171 443.0
PYH3_k127_387454_1 SMART Ras small GTPase, Ras type - - - 0.0000000000000000000000005305 117.0
PYH3_k127_387454_2 formylmethanofuran dehydrogenase, subunit E - - - 0.00000000000002526 84.0
PYH3_k127_387454_3 KaiC K08482 - - 0.00000000006195 72.0
PYH3_k127_387454_4 Bacterial transcriptional activator domain - - - 0.00007444 55.0
PYH3_k127_3911786_0 NAD FAD dependent dehydrogenase K12164 - - 0.0000000000000000000000000000000000000000000000000008117 193.0
PYH3_k127_3911786_1 SPFH domain-Band 7 family - - - 0.000005463 53.0
PYH3_k127_3950425_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03237 GO:0003674,GO:0003676,GO:0003723,GO:0003743,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006413,GO:0006518,GO:0006807,GO:0008135,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0019538,GO:0032991,GO:0034641,GO:0034645,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0044877,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007822 323.0
PYH3_k127_3950425_1 PAC2 family K07159 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000001912 286.0
PYH3_k127_3950425_2 Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate K01807 GO:0003674,GO:0003824,GO:0004751,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005975,GO:0005996,GO:0006014,GO:0006081,GO:0006098,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009052,GO:0009117,GO:0009987,GO:0016853,GO:0016860,GO:0016861,GO:0019321,GO:0019362,GO:0019637,GO:0019682,GO:0019693,GO:0034641,GO:0044237,GO:0044238,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046496,GO:0051156,GO:0051186,GO:0055086,GO:0071704,GO:0072524,GO:1901135,GO:1901360,GO:1901564 5.3.1.6 0.00000000000000000000000000000000000000000000000000000000000000005058 230.0
PYH3_k127_3950425_3 binds to the 23S rRNA K02929 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0015934,GO:0022625,GO:0022626,GO:0032991,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:1990904 - 0.0000000000000000000000000000000003296 133.0
PYH3_k127_3950425_4 Transcriptional regulator, TrmB - - - 0.0000000000000000000000000000001146 127.0
PYH3_k127_3950425_5 ribosomal protein K02978 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000192 82.0
PYH3_k127_3950425_6 more specifically in 18S rRNA pseudouridylation and in cleavage of pre-rRNA K11130 - - 0.0000000000001616 72.0
PYH3_k127_3950425_7 Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase K02488 - 2.7.7.65 0.0000000000008451 77.0
PYH3_k127_3960299_0 Cysteinyl-tRNA synthetase K01883 GO:0000166,GO:0003674,GO:0003824,GO:0004812,GO:0004817,GO:0005488,GO:0005524,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006423,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0017076,GO:0019538,GO:0019752,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034645,GO:0034660,GO:0035639,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:0140101,GO:1901265,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005418 404.0
PYH3_k127_3960299_1 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006577 385.0
PYH3_k127_3960299_2 anaphase-promoting complex binding - - - 0.00000000000000000000000000000001792 149.0
PYH3_k127_3960299_3 Belongs to the peptidase S8 family K01361,K08652 - 3.4.21.110,3.4.21.96 0.000003103 62.0
PYH3_k127_3967298_0 Amidohydrolase family K12960 - 3.5.4.28,3.5.4.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000292 445.0
PYH3_k127_3967298_1 General factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Binds specifically to the TATA box promoter element which lies close to the position of transcription initiation K03120 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000007581 263.0
PYH3_k127_3967298_10 KaiC - - - 0.00000000000000000003713 97.0
PYH3_k127_3967298_11 PFAM acylphosphatase K01512 GO:0003674,GO:0003824,GO:0003998,GO:0016787,GO:0016817,GO:0016818 3.6.1.7 0.00000000000000001315 95.0
PYH3_k127_3967298_12 DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function K04485 - - 0.000000000001548 76.0
PYH3_k127_3967298_13 COG0517 FOG CBS domain - - - 0.000000000005016 78.0
PYH3_k127_3967298_14 SCP-2 sterol transfer family - - - 0.0000000005313 69.0
PYH3_k127_3967298_15 Parallel beta-helix repeats - - - 0.0001668 54.0
PYH3_k127_3967298_2 TatD related DNase K07049 - - 0.00000000000000000000000000000000000000000000000000000000000000006541 233.0
PYH3_k127_3967298_3 Endonuclease that specifically degrades the RNA of RNA- DNA hybrids K03470 GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004523,GO:0004540,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006271,GO:0006273,GO:0006281,GO:0006298,GO:0006401,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0019439,GO:0022616,GO:0032299,GO:0032991,GO:0033554,GO:0033567,GO:0034641,GO:0034645,GO:0034655,GO:0043137,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0140098,GO:1901360,GO:1901361,GO:1901575,GO:1901576 3.1.26.4 0.0000000000000000000000000000000000000000000000000000001117 211.0
PYH3_k127_3967298_4 Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid K00077 - 1.1.1.169 0.000000000000000000000000000000000000000000000000000003941 202.0
PYH3_k127_3967298_5 DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA K05982 - 3.1.21.7 0.00000000000000000000000000000000000004352 160.0
PYH3_k127_3967298_6 DnaB-like helicase C terminal domain K08482 - - 0.00000000000000000000000000000000007359 149.0
PYH3_k127_3967298_7 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000246 138.0
PYH3_k127_3967298_8 ATPase, AAA superfamily K01733,K02039,K03436,K03524,K03655 - 3.6.4.12,4.2.3.1,6.3.4.15 0.00000000000000000000008452 113.0
PYH3_k127_3967298_9 peptidase M36 K01417 - - 0.000000000000000000008373 108.0
PYH3_k127_3975363_0 regulator of chromosome condensation, RCC1 - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001155 400.0
PYH3_k127_3975363_1 regulator of chromosome condensation, RCC1 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002264 371.0
PYH3_k127_3975363_2 Peptidase C13 family - - - 0.000001546 54.0
PYH3_k127_3983366_0 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K00342,K05568 - 1.6.5.3 0.0 1122.0
PYH3_k127_3983366_1 Formate hydrogenlyase subunit 3 Multisubunit Na H antiporter, MnhD subunit K05568 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 310.0
PYH3_k127_3983366_2 PFAM NADH ubiquinone oxidoreductase 20 kDa subunit K14088 - - 0.000000000000000000000000000000000000000000000000000000000000000008784 228.0
PYH3_k127_3983366_3 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000002068 200.0
PYH3_k127_3983366_5 Multisubunit Na H antiporter MnhC subunit K00340,K05567,K14114 - 1.6.5.3 0.000000128 60.0
PYH3_k127_4094313_0 PFAM Thiolase K00626 - 2.3.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002806 484.0
PYH3_k127_4094313_1 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III C terminal K01641 - 2.3.3.10 0.00000000000000000000000000000000000000000000000000000000000000000000005992 243.0
PYH3_k127_4113508_0 Pyruvate:ferredoxin oxidoreductase core domain II K00169,K00186 - 1.2.7.1,1.2.7.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008694 407.0
PYH3_k127_4113508_1 Thiamine pyrophosphate enzyme, C-terminal TPP binding domain K00170,K00187 - 1.2.7.1,1.2.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 382.0
PYH3_k127_4113508_2 oxidoreductase K17218 - 1.8.5.4 0.00000000000000000000000000000000000000000000000000000000000002295 228.0
PYH3_k127_4113508_3 Pyruvate ferredoxin/flavodoxin oxidoreductase K00172,K00189 - 1.2.7.1,1.2.7.7 0.000000000000000000000000000000000000000000000000000000006093 204.0
PYH3_k127_4113508_4 Phosphate uptake regulator - - - 0.000000000000000000000000000000000000000000000000002287 196.0
PYH3_k127_4113508_5 PAC2 family K06869 - - 0.00000000000000000000000000000000000000002216 162.0
PYH3_k127_4113508_6 3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity K00188 - 1.2.7.7 0.000000000000000000000001164 111.0
PYH3_k127_4113508_7 PFAM DoxX family protein K16937 - 1.8.5.2 0.000000000000003067 83.0
PYH3_k127_4113508_8 bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding - - - 0.00007494 46.0
PYH3_k127_4125849_0 Pyridine nucleotide-disulphide oxidoreductase K00384,K03387,K21567 - 1.18.1.2,1.19.1.1,1.8.1.9 0.000000000000000000000000000000000000000000000000000000000000000000000004372 256.0
PYH3_k127_4125849_1 Putative RNA-binding Domain in PseudoUridine synthase and Archaeosine transglycosylase K07575 - - 0.00000000000000000000000000000000000000000000001967 175.0
PYH3_k127_4125849_2 - - - - 0.000000000000000000000000000000000000007059 150.0
PYH3_k127_4125849_3 DnaB-like helicase C terminal domain - - - 0.0000000000000000000000000000909 127.0
PYH3_k127_4125849_4 Pfam:DUF552 K09152 - - 0.0000000000000000000000001457 111.0
PYH3_k127_4125849_5 Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress K01091 - 3.1.3.18 0.000000000000000000000421 105.0
PYH3_k127_4171880_0 CobW/HypB/UreG, nucleotide-binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007937 592.0
PYH3_k127_4171880_1 Belongs to the peptidase S8 family - - - 0.00000000000000000000000000000000000000000000000000000000004013 228.0
PYH3_k127_4240279_0 Thiolase, C-terminal domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008013 425.0
PYH3_k127_4240279_1 CoA-transferase family III - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000003369 282.0
PYH3_k127_4264381_0 Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine K13038 - 4.1.1.36,6.3.2.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006697 335.0
PYH3_k127_4264381_1 Mur ligase middle domain K11754 - 6.3.2.12,6.3.2.17 0.000000000000000000000000000000001754 135.0
PYH3_k127_4264381_2 PFAM GHMP kinase K06982 - 2.7.1.169 0.00000000000000000000000000000003989 132.0
PYH3_k127_4272769_0 Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain K01872 GO:0000049,GO:0002161,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0004812,GO:0004813,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006412,GO:0006418,GO:0006419,GO:0006450,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016597,GO:0016787,GO:0016788,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0031406,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0036094,GO:0043038,GO:0043039,GO:0043043,GO:0043167,GO:0043168,GO:0043170,GO:0043177,GO:0043412,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0052689,GO:0065007,GO:0065008,GO:0071704,GO:0090304,GO:0097159,GO:0106074,GO:0140098,GO:0140101,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576 6.1.1.7 1.381e-235 750.0
PYH3_k127_4272769_1 ASPIC and UnbV - - - 0.0000000000000000000000000000000000000000000000000005925 209.0
PYH3_k127_4299790_0 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 1.146e-236 743.0
PYH3_k127_4299790_1 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K03431 - 5.4.2.10 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001177 462.0
PYH3_k127_4299790_10 PFAM Inositol monophosphatase K01092 - 3.1.3.25 0.000000000000000000000000000002782 135.0
PYH3_k127_4299790_11 - - - - 0.00000000000000000001406 93.0
PYH3_k127_4299790_12 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000005583 78.0
PYH3_k127_4299790_2 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K01845 - 5.4.3.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001996 431.0
PYH3_k127_4299790_3 PFAM transferase hexapeptide repeat containing protein K04042 - 2.3.1.157,2.7.7.23 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005294 405.0
PYH3_k127_4299790_4 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 GO:0000166,GO:0003674,GO:0003824,GO:0003951,GO:0005488,GO:0005524,GO:0006139,GO:0006725,GO:0006732,GO:0006733,GO:0006739,GO:0006741,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008144,GO:0008150,GO:0008152,GO:0009058,GO:0009108,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016311,GO:0016740,GO:0016772,GO:0016773,GO:0016787,GO:0016788,GO:0016791,GO:0017076,GO:0018130,GO:0019178,GO:0019359,GO:0019362,GO:0019363,GO:0019438,GO:0019637,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0034641,GO:0034654,GO:0035639,GO:0036094,GO:0042578,GO:0043167,GO:0043168,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0046483,GO:0046496,GO:0048037,GO:0050662,GO:0051186,GO:0051188,GO:0051287,GO:0055086,GO:0071704,GO:0072524,GO:0072525,GO:0090407,GO:0097159,GO:0097367,GO:1901265,GO:1901293,GO:1901360,GO:1901362,GO:1901363,GO:1901564,GO:1901566,GO:1901576 2.7.1.23 0.00000000000000000000000000000000000000000000000000000000000000000006024 242.0
PYH3_k127_4299790_5 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000000000006043 208.0
PYH3_k127_4299790_6 Saccharopine dehydrogenase K00290 - 1.5.1.7 0.00000000000000000000000000000000000000000001069 180.0
PYH3_k127_4299790_7 PFAM binding-protein-dependent transport systems inner membrane component K11071 - - 0.0000000000000000000000000000000000000002184 172.0
PYH3_k127_4299790_8 PFAM binding-protein-dependent transport systems inner membrane component K11070 - - 0.000000000000000000000000000000000001408 160.0
PYH3_k127_4299790_9 metal-dependent protease of the PAD1 JAB1 superfamily - - - 0.00000000000000000000000000000001572 141.0
PYH3_k127_4304384_0 Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose K01711 - 4.2.1.47 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003337 412.0
PYH3_k127_4304384_1 Glycosyltransferase Family 4 - - - 0.000000000000000000000000000000000000000000000000000000002469 213.0
PYH3_k127_4304384_2 - - - - 0.00000000000000000000000000000001524 132.0
PYH3_k127_4304384_3 PFAM Glycosyl transferases group 1 - - - 0.000000000000000000000000000000169 136.0
PYH3_k127_4304384_4 PFAM glycosyl transferase group 1 - - - 0.00000000000000000000000008435 119.0
PYH3_k127_4304384_5 Methyltransferase domain - - - 0.000000000004577 77.0
PYH3_k127_4304384_6 NAD(P)H-binding K01784 - 5.1.3.2 0.0000000007844 62.0
PYH3_k127_4353555_0 PFAM TPR repeat-containing protein - - - 0.0000000000008724 81.0
PYH3_k127_4359110_0 Helix-turn-helix XRE-family like proteins K07728 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000007211 260.0
PYH3_k127_4359110_1 - - - - 0.0000000000000000000000003025 113.0
PYH3_k127_4359110_2 cellulase activity - - - 0.0000000339 68.0
PYH3_k127_4359110_4 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.00001608 50.0
PYH3_k127_4365048_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03041 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.0 1274.0
PYH3_k127_4365048_1 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 3.53e-231 734.0
PYH3_k127_4365048_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03042 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007663 390.0
PYH3_k127_4365048_3 Participates in transcription termination K02600 - - 0.000000000000000000000000000000000000000000009719 166.0
PYH3_k127_4365048_4 Belongs to the UPF0145 family - - - 0.00000000000000000000000000351 114.0
PYH3_k127_4365048_5 PFAM ribosomal protein L7Ae L30e S12e Gadd45 K02908 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.00000000000000005043 95.0
PYH3_k127_4393257_0 biotin lipoate A B protein ligase K03524 - 6.3.4.15 0.00000000000000000000000000000000000000001484 164.0
PYH3_k127_4393257_1 PFAM Glyoxalase bleomycin resistance protein dioxygenase K05606 - 5.1.99.1 0.000000000000000000000000000000000000002716 149.0
PYH3_k127_4393257_2 Methylmalonyl-CoA mutase K01848 - 5.4.99.2 0.00000000116 61.0
PYH3_k127_4416308_0 - - - - 0.000000000000000000000000000002628 136.0
PYH3_k127_4416308_1 EamA-like transporter family - - - 0.000000000000000000000000001383 121.0
PYH3_k127_4416308_2 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.00001716 49.0
PYH3_k127_4423507_0 DEAD_2 K10844 - 3.6.4.12 0.000000000000000000000000000000000000000000000000000000000000000006755 255.0
PYH3_k127_4423507_1 Protein kinase domain K08851,K15904 GO:0000408,GO:0002949,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:1901360 2.3.1.234,2.7.11.1 0.0000000000000000000000000000000003306 136.0
PYH3_k127_4423507_2 - - - - 0.0000000000000322 78.0
PYH3_k127_4427314_0 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.000000000000000000000000000000000000000000337 184.0
PYH3_k127_4427314_1 PFAM PKD domain containing protein - - - 0.0000005582 64.0
PYH3_k127_4427314_2 Belongs to the glycosyl hydrolase 32 family K01193,K01212,K03332 GO:0003674,GO:0003824,GO:0004553,GO:0004564,GO:0005975,GO:0005984,GO:0005985,GO:0005987,GO:0008150,GO:0008152,GO:0009056,GO:0009311,GO:0009313,GO:0009987,GO:0016052,GO:0016787,GO:0016798,GO:0044237,GO:0044238,GO:0044248,GO:0044262,GO:0044275,GO:0046352,GO:0071704,GO:1901575 3.2.1.26,3.2.1.65,3.2.1.80 0.000001273 63.0
PYH3_k127_4431325_0 Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro) K01881 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.15 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001673 554.0
PYH3_k127_4431325_1 Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) K01866 GO:0003674,GO:0003824,GO:0004812,GO:0004831,GO:0004832,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006438,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016875,GO:0019538,GO:0019752,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564,GO:1901566,GO:1901576 6.1.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001886 304.0
PYH3_k127_4431325_2 Met-10+ like-protein K07055 GO:0003674,GO:0003824,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016740,GO:0016765,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 2.5.1.114 0.0000000000000000000000000000000000000000000000000000000003316 215.0
PYH3_k127_4431325_3 COG1361 S-layer domain - - - 0.00000000000000002932 94.0
PYH3_k127_4467202_0 NAD(P)-binding Rossmann-like domain K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001575 320.0
PYH3_k127_4467202_1 Pyruvate ferredoxin/flavodoxin oxidoreductase K00177 - 1.2.7.3 0.000000000000000000000000000000000000000000000000741 181.0
PYH3_k127_4467202_2 ferredoxin oxidoreductase beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000009925 173.0
PYH3_k127_4478973_0 Aldehyde dehydrogenase family K00294 - 1.2.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001937 550.0
PYH3_k127_4478973_1 - - - - 0.000000000000000000000000000000002565 139.0
PYH3_k127_4511476_0 PFAM TPR repeat-containing protein - - - 0.0000000000000000000000000000000000000000004753 183.0
PYH3_k127_4511476_1 Circadian clock protein KaiC - - - 0.00000000000461 73.0
PYH3_k127_4511476_2 COG0467 RecA-superfamily ATPases implicated in signal transduction - - - 0.00000000008392 76.0
PYH3_k127_4566195_0 Heterodisulfide reductase subunit A and related polyferredoxins K03388 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 5.315e-274 863.0
PYH3_k127_4566195_1 Nickel-dependent hydrogenase K14126 - 1.8.98.5 2.766e-232 726.0
PYH3_k127_4566195_10 Probably plays a role in a hydrogenase nickel cofactor insertion step K04651 - - 0.0000000002182 70.0
PYH3_k127_4566195_11 HupF/HypC family - - - 0.000000003827 60.0
PYH3_k127_4566195_12 PFAM regulatory protein AsnC Lrp family - - - 0.00001476 52.0
PYH3_k127_4566195_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K14128 - 1.8.98.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005689 454.0
PYH3_k127_4566195_3 Heterodisulfide reductase subunit B K03389 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000006367 311.0
PYH3_k127_4566195_4 Methyl-viologen-reducing hydrogenase, delta subunit K14127,K14128 - 1.8.98.5,1.8.98.6 0.00000000000000000000000000000000000000000000000000000001895 200.0
PYH3_k127_4566195_5 4Fe-4S dicluster domain K03389,K03390,K16887,K18930 - 1.8.7.3,1.8.98.4,1.8.98.5,1.8.98.6 0.0000000000000000000000000000000000000000000000000000002634 202.0
PYH3_k127_4566195_6 Protein of unknown function (DUF1684) K09164 - - 0.0000000000000000000000000000000000000000000000002911 183.0
PYH3_k127_4566195_7 Ras of Complex, Roc, domain of DAPkinase - - - 0.00000000000000000000002538 110.0
PYH3_k127_4566195_8 Hydrogenase maturation protease - - - 0.0000000000000000000001353 108.0
PYH3_k127_4566195_9 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.000000000001472 82.0
PYH3_k127_4576657_0 Aldolase/RraA K13831 - 4.1.2.43,5.3.1.27 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 515.0
PYH3_k127_4576657_1 (AIR) carboxylase K06898 - - 0.0000000000000000126 91.0
PYH3_k127_4587943_0 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.0000000000000000000000000000000000000000000000000000000000005426 215.0
PYH3_k127_4587943_1 Membrane - - - 0.0000008643 60.0
PYH3_k127_4696058_0 Component of the wyosine derivatives biosynthesis pathway that catalyzes the condensation of N-methylguanine with 2 carbon atoms from pyruvate to form the tricyclic 4-demethylwyosine (imG-14) on guanosine-37 of tRNA(Phe) K15449 - 4.1.3.44 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008286 372.0
PYH3_k127_4696058_1 Nucleolar GTP-binding protein 1 (NOG1) K06943 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002697 308.0
PYH3_k127_4696058_2 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04800 - - 0.0000000000000000000000000000000000000000000000000000428 198.0
PYH3_k127_4696058_3 Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively K06215 - 4.3.3.6 0.0000000000000000000000000000000000000000000000005909 177.0
PYH3_k127_4696058_4 membrane - - - 0.00000000003807 70.0
PYH3_k127_4696058_5 Protein conserved in bacteria K07192 - - 0.0004125 51.0
PYH3_k127_4705075_0 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 - 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005435 514.0
PYH3_k127_4716926_0 TIGRFAM 2-oxoacid acceptor oxidoreductase, alpha subunit K00174 - 1.2.7.11,1.2.7.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005877 467.0
PYH3_k127_4716926_1 TIGRFAM pyruvate ferredoxin flavodoxin oxidoreductase, beta subunit K00175 - 1.2.7.11,1.2.7.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006024 361.0
PYH3_k127_4716926_2 LUD domain - - - 0.000000000000000000000000000000000001873 155.0
PYH3_k127_4716926_3 Translation initiation factor K03680 - - 0.0000000000000000000000003445 115.0
PYH3_k127_4744132_0 DnaB-like helicase C terminal domain K08482 - - 0.0000000001319 71.0
PYH3_k127_4756811_0 Carboxypeptidase regulatory-like domain K07151 - 2.4.99.18 1.663e-227 779.0
PYH3_k127_4756811_1 Pfam:KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000003904 257.0
PYH3_k127_4756811_3 Protein of unknown function (DUF1349) - - - 0.000000000000000000000000000000000000000000000000000000000002784 239.0
PYH3_k127_4756811_4 Roadblock LC7 family protein - - - 0.00000000000000000000000000000000000000002216 169.0
PYH3_k127_4756811_6 pre-rRNA processing protein involved in ribosome biogenesis K09140 GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0030490,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360 - 0.000000000000000000000000000000000001359 151.0
PYH3_k127_4756811_7 Belongs to the UPF0434 family - - - 0.00000000000002717 86.0
PYH3_k127_4756811_8 - - - - 0.0000000008683 69.0
PYH3_k127_4817246_0 protein conserved in archaea K09746 - - 0.0000000000000000000000000000000000000000000000000000000000000009323 241.0
PYH3_k127_4817246_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.00000000000000000000000000000000000000000000000000000001575 207.0
PYH3_k127_4823090_0 Leucyl aminopeptidase (Aminopeptidase T) K19689 - - 0.0000000000000003261 92.0
PYH3_k127_4823090_1 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01534 - 3.6.3.3,3.6.3.5 0.00009372 53.0
PYH3_k127_4929520_0 Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs K18779 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008616,GO:0009058,GO:0009116,GO:0009119,GO:0009163,GO:0009987,GO:0018130,GO:0019438,GO:0034404,GO:0034641,GO:0034654,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046116,GO:0046483,GO:0055086,GO:0071704,GO:1901135,GO:1901137,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 2.4.2.48 0.000000000000000000000000001968 113.0
PYH3_k127_4929520_1 - - - - 0.00005266 52.0
PYH3_k127_4933611_0 Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits K03236 - - 0.000000000000000000000000000000000000000003121 158.0
PYH3_k127_4933611_1 - - - - 0.0000000009873 72.0
PYH3_k127_4933611_2 COG3227 Zinc metalloprotease (elastase) K08604 - 3.4.24.25 0.00000002683 62.0
PYH3_k127_4945376_0 ABC-type Fe3 transport system permease component K02053,K02054,K02063 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001026 428.0
PYH3_k127_4945376_1 Phosphate transport regulator K07220 - - 0.000000000000000000000000000000000000000000000000003439 188.0
PYH3_k127_4945376_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000001741 129.0
PYH3_k127_4945376_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY K03106 - 3.6.5.4 0.000000000000094 74.0
PYH3_k127_4981988_0 ABC-type transport system, involved in lipoprotein release, permease component K09808 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002169 346.0
PYH3_k127_4981988_1 Part of the ABC transporter complex LolCDE involved in the translocation of lipoproteins, in an ATP-dependent manner K09810 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005262 320.0
PYH3_k127_4981988_2 B12 binding domain - - - 0.0000000000000000000000000000000000000000000000000000000000001127 222.0
PYH3_k127_4981988_3 Thioesterase superfamily - - - 0.0000000000000000000000000000000000000000000009851 167.0
PYH3_k127_5001276_0 Sugar (and other) transporter - - - 0.0000000000000000000000000000000000000000000001016 179.0
PYH3_k127_5007335_0 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 472.0
PYH3_k127_5007335_1 TIGRFAM oligopeptide dipeptide ABC transporter K02031,K02032 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005458 357.0
PYH3_k127_5007335_10 Parallel beta-helix repeats - - - 0.00002376 57.0
PYH3_k127_5007335_2 Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration K17758,K17759 - 4.2.1.136,5.1.99.6 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002782 334.0
PYH3_k127_5007335_3 Sodium/calcium exchanger protein K07300 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008227 319.0
PYH3_k127_5007335_4 N-terminal TM domain of oligopeptide transport permease C K02034 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000006622 304.0
PYH3_k127_5007335_5 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.0000000000000000000000000000000000000000000000000000000000000000171 254.0
PYH3_k127_5007335_6 Binding-protein-dependent transport system inner membrane component K02033 - - 0.00000000000000000000000000000000000000000000000000000000000465 228.0
PYH3_k127_5007335_7 ICC-like phosphoesterases K06953 - - 0.0000000000000000000000000000000000000000000000000000003727 203.0
PYH3_k127_5007335_8 Major Facilitator Superfamily - - - 0.000000000000000000000000000000000000000000001487 169.0
PYH3_k127_5007335_9 Periplasmic copper-binding protein (NosD) - - - 0.00001799 57.0
PYH3_k127_5022573_0 PFAM Aldehyde dehydrogenase family K00128,K00130,K00151,K10217 - 1.2.1.3,1.2.1.32,1.2.1.60,1.2.1.8,1.2.1.85 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008092 492.0
PYH3_k127_5022573_1 poly(R)-hydroxyalkanoic acid synthase subunit PhaC K03821 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001796 367.0
PYH3_k127_5022573_2 MMPL family K06994 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005239 376.0
PYH3_k127_5022573_3 Enoyl-(Acyl carrier protein) reductase K00059 - 1.1.1.100 0.00000000000000000000000000000000000000000000000000000000000000000000000001104 266.0
PYH3_k127_5022573_4 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.000000000000000000000000000000000000000000000000000000000000000002266 235.0
PYH3_k127_5022573_5 lactoylglutathione lyase activity K01759 - 4.4.1.5 0.000000000000388 79.0
PYH3_k127_5022573_6 poly-hydroxybutyrate biosynthetic process - - - 0.0000008463 58.0
PYH3_k127_5022579_0 amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) K01870 - 6.1.1.5 0.000000000000000113 97.0
PYH3_k127_5022579_1 OmpA family - - - 0.000000000006623 81.0
PYH3_k127_5022579_2 - - - - 0.000000002432 66.0
PYH3_k127_5056922_0 Belongs to the complex I 49 kDa subunit family K00333,K13378 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002526 361.0
PYH3_k127_5056922_1 NADH ubiquinone oxidoreductase 27 kD subunit K00332,K22160 - 1.5.98.3,1.6.5.3 0.000000000000000000000000000005104 125.0
PYH3_k127_5056922_2 COG2041 Sulfite oxidase and related enzymes - - - 0.00000000000000000000569 94.0
PYH3_k127_5056922_3 NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 K22158 GO:0003674,GO:0003824,GO:0008150,GO:0008152,GO:0016491,GO:0016695,GO:0046995,GO:0051911,GO:0055114 1.5.98.3 0.00000000000001358 78.0
PYH3_k127_5071590_0 Aldo/keto reductase family K00002 - 1.1.1.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007175 352.0
PYH3_k127_5071590_1 Enoyl-(Acyl carrier protein) reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000525 291.0
PYH3_k127_5071590_2 Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD K01802,K03768 - 5.2.1.8 0.00000000000000000000000000000000000009694 143.0
PYH3_k127_5071590_3 Coenzyme A transferase K01040 - 2.8.3.12 0.00000000000000000000000000000118 130.0
PYH3_k127_5071590_4 Phospholipid methyltransferase - - - 0.00000000001731 72.0
PYH3_k127_5071590_5 Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella - - - 0.00000005847 62.0
PYH3_k127_5102500_0 Phytoene dehydrogenase K10027 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001349 449.0
PYH3_k127_5102500_1 Bacterial protein of unknown function (DUF885) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006209 340.0
PYH3_k127_5102500_10 Phytoene synthase K21678 - 2.5.1.103 0.00000002788 65.0
PYH3_k127_5102500_11 Lrp/AsnC ligand binding domain - - - 0.0003096 53.0
PYH3_k127_5102500_2 Major facilitator superfamily - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000001017 306.0
PYH3_k127_5102500_3 Methyltransferase involved in ribosomal biogenesis. Specifically catalyzes the N1-methylation of the pseudouridine corresponding to position 914 in M.jannaschii 16S rRNA K14568 GO:0000154,GO:0000462,GO:0001510,GO:0003674,GO:0003676,GO:0003723,GO:0003824,GO:0005488,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016740,GO:0016741,GO:0019843,GO:0022613,GO:0030490,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0046483,GO:0070037,GO:0070475,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:0140098,GO:0140102,GO:1901360,GO:1901363 2.1.1.260 0.00000000000000000000000000000000000000000000000000000002923 205.0
PYH3_k127_5102500_4 ATP-dependent protease La (LON) substrate-binding domain K01338,K07157 - 3.4.21.53 0.0000000000000000000000000000000388 137.0
PYH3_k127_5102500_5 Bacterial regulatory proteins, tetR family - - - 0.0000000000000000000000000455 116.0
PYH3_k127_5102500_6 hemerythrin HHE cation binding domain - - - 0.00000000000000000000000023 113.0
PYH3_k127_5102500_7 Uncharacterised protein family (UPF0147) K09721 - - 0.0000000000000000000000008777 106.0
PYH3_k127_5102500_8 - - - - 0.00000000000003939 78.0
PYH3_k127_5102500_9 zinc-ribbon domain - - - 0.000000009433 66.0
PYH3_k127_5131168_0 Phosphate transport regulator K07220 - - 0.00000000000000000000000000000000000000000000000000000000166 208.0
PYH3_k127_5131168_1 PFAM phosphate transporter K03306 - - 0.00000000000000000000000000000000000000000000000000002818 203.0
PYH3_k127_5131168_2 ABC transporter K02010,K02017,K02052,K02062,K10112,K11072,K15497,K17240 - 3.6.3.29,3.6.3.30,3.6.3.31,3.6.3.55 0.0000000000000000000000000000000000000000000000000003227 194.0
PYH3_k127_5131168_3 Phosphate transport regulator K07220 - - 0.000000000000000000003885 101.0
PYH3_k127_5132783_0 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02469 - 5.99.1.3 8.83e-245 781.0
PYH3_k127_5132783_1 A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner K02470 - 5.99.1.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000239 360.0
PYH3_k127_5132783_2 peptidase dimerisation domain protein - - - 0.00008235 46.0
PYH3_k127_5155233_0 Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3- polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN K03186 - 2.5.1.129 0.000000000000000000000000000000000000000000000000002106 188.0
PYH3_k127_5155233_1 May be involved in maturation of the 30S ribosomal subunit K02966 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.0000000000000000000000000000000000000000000000004749 188.0
PYH3_k127_5155233_2 Belongs to the PDCD5 family K06875 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0044424,GO:0044444,GO:0044464 - 0.000000000000000000004257 102.0
PYH3_k127_5155233_3 Belongs to the ribosomal protein L31e family K02910 GO:0002181,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000245 82.0
PYH3_k127_5155233_4 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000000008493 92.0
PYH3_k127_5155233_5 Belongs to the eukaryotic ribosomal protein eL39 family K02924 - - 0.00000000001261 65.0
PYH3_k127_5187121_0 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007061 558.0
PYH3_k127_5187121_1 regulator of chromosome condensation, RCC1 - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000005094 299.0
PYH3_k127_5187121_2 isomerase activity K06998 - 5.3.3.17 0.00000000000000000000000000000000000000007986 159.0
PYH3_k127_5187121_3 Bacterial Ig-like domain (group 3) K20276 - - 0.000000006628 70.0
PYH3_k127_5187121_4 - - - - 0.00002366 50.0
PYH3_k127_5187121_5 COG3277 RNA-binding protein involved in rRNA processing K07569 - - 0.0002737 51.0
PYH3_k127_5244231_0 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03044,K13798 GO:0000428,GO:0005575,GO:0005622,GO:0005623,GO:0030880,GO:0032991,GO:0044424,GO:0044464,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 1.323e-227 716.0
PYH3_k127_5244231_1 PFAM CutA1 divalent ion tolerance protein K03926 - - 0.00000000000000000000000000006993 118.0
PYH3_k127_5244231_2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03053 - 2.7.7.6 0.00000000000000000000005518 103.0
PYH3_k127_5244231_3 Promotes the exchange of GDP for GTP in EF-1-alpha GDP, thus allowing the regeneration of EF-1-alpha GTP that could then be used to form the ternary complex EF-1-alpha GTP AAtRNA K03232 - - 0.000000000000006292 80.0
PYH3_k127_5244231_4 Domain of unknown function (DUF1610) K07580 - - 0.0000000000003683 70.0
PYH3_k127_5270565_0 membrane protein, required for N-linked glycosylation K07151 GO:0000030,GO:0003674,GO:0003824,GO:0004169,GO:0005575,GO:0005623,GO:0005886,GO:0006464,GO:0006486,GO:0006493,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009100,GO:0009101,GO:0009987,GO:0016020,GO:0016740,GO:0016757,GO:0016758,GO:0019538,GO:0034645,GO:0035268,GO:0035269,GO:0036211,GO:0043170,GO:0043412,GO:0043413,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044464,GO:0070085,GO:0071704,GO:0071944,GO:0097502,GO:1901135,GO:1901137,GO:1901564,GO:1901566,GO:1901576 2.4.99.18 0.0000000001059 74.0
PYH3_k127_5270565_1 COG0438 Glycosyltransferase - - - 0.00004956 48.0
PYH3_k127_5286085_0 CYTH domain - - - 0.000000000000000000001623 102.0
PYH3_k127_5286085_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.000000000001635 73.0
PYH3_k127_5286085_2 acetyltransferase - - - 0.0000004717 58.0
PYH3_k127_5286780_0 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.0000000000000003116 89.0
PYH3_k127_5286780_1 Acetyltransferase (GNAT) domain - - - 0.000000001446 66.0
PYH3_k127_5296477_0 Acyl-CoA dehydrogenase, C-terminal domain K00248 - 1.3.8.1 0.0000000000000000000000000000000000000000000000000000000000000000000008163 241.0
PYH3_k127_5296477_1 metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain K07050 - - 0.00000000000000000000000000000000000000000000000000000002788 214.0
PYH3_k127_5296477_2 Catalyzes the reversible oxidation of malate to oxaloacetate K00024 - 1.1.1.37 0.0000000000000000000000000003566 119.0
PYH3_k127_5351592_0 Belongs to the peptidase S8 family - GO:0005575,GO:0005623,GO:0031975,GO:0044464 - 0.0000000000000000000000000000000000000001141 174.0
PYH3_k127_5351592_1 Caspase domain - - - 0.000000000000000000000000742 122.0
PYH3_k127_5367814_0 Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA K01895 - 6.2.1.1 2.779e-296 922.0
PYH3_k127_5367814_1 KH, type 1, domain K07041 - - 2.278e-264 828.0
PYH3_k127_5367814_2 TCP-1/cpn60 chaperonin family K22447 GO:0003674,GO:0005488,GO:0005515,GO:0006457,GO:0006458,GO:0008150,GO:0009987,GO:0044183,GO:0051082,GO:0061077 - 3.7e-225 709.0
PYH3_k127_5367814_3 acetyl-CoA hydrolase transferase - - - 3.924e-216 688.0
PYH3_k127_5367814_4 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03433 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0004298,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019774,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070003,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.00000000000000000000000000000000000000000000000000000000000000000004248 238.0
PYH3_k127_5367814_5 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000007768 86.0
PYH3_k127_5367814_6 PFAM Threonyl alanyl tRNA synthetase, SAD K07050 - - 0.0000156 51.0
PYH3_k127_5367814_7 Major facilitator superfamily K08177 - - 0.00007138 47.0
PYH3_k127_5367814_8 Acetyltransferase (GNAT) domain - - - 0.0004568 49.0
PYH3_k127_5385528_0 Signal peptidase K13280 - 3.4.21.89 0.00000000000000000000000000000000002261 148.0
PYH3_k127_5385528_1 PFAM metallophosphoesterase - - - 0.0000000000000000000008859 99.0
PYH3_k127_5386900_0 Belongs to the formate--tetrahydrofolate ligase family K01938 - 6.3.4.3 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000138 614.0
PYH3_k127_5386900_1 amino acid - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000916 278.0
PYH3_k127_5386900_2 but it may be involved in stabilization of the trimeric complex - - - 0.000008726 53.0
PYH3_k127_5437535_0 Trypsin-like serine protease with C-terminal PDZ domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000004237 263.0
PYH3_k127_5437535_1 Transcriptional regulator PadR-like family - - - 0.0000000000000000000000319 103.0
PYH3_k127_5437535_2 Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre- crRNA and tracrRNA of type II CRISPR loci if present in the organism K03685 - 3.1.26.3 0.000000000000000000001826 98.0
PYH3_k127_5437535_3 ABC transporter K01990 - - 0.000002436 52.0
PYH3_k127_5470584_0 Belongs to the class-I aminoacyl-tRNA synthetase family K01869 - 6.1.1.4 9.058e-288 913.0
PYH3_k127_5470584_1 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 - - 0.000000000000008309 80.0
PYH3_k127_5539648_0 PFAM Histone deacetylase K04768 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 332.0
PYH3_k127_5539648_1 Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine K13571 GO:0000166,GO:0000302,GO:0003674,GO:0003824,GO:0005488,GO:0005524,GO:0005575,GO:0005618,GO:0005623,GO:0005886,GO:0006464,GO:0006508,GO:0006807,GO:0006950,GO:0006979,GO:0008144,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009405,GO:0009987,GO:0010035,GO:0010498,GO:0016020,GO:0016740,GO:0016874,GO:0016879,GO:0016881,GO:0017076,GO:0018193,GO:0018205,GO:0019538,GO:0019787,GO:0019941,GO:0030163,GO:0030312,GO:0030554,GO:0032446,GO:0032553,GO:0032555,GO:0032559,GO:0033554,GO:0034599,GO:0034614,GO:0035639,GO:0035690,GO:0036094,GO:0036211,GO:0042221,GO:0042493,GO:0043167,GO:0043168,GO:0043170,GO:0043412,GO:0043632,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044419,GO:0044464,GO:0050896,GO:0051409,GO:0051603,GO:0051704,GO:0051716,GO:0070490,GO:0070647,GO:0070887,GO:0071241,GO:0071704,GO:0071731,GO:0071732,GO:0071944,GO:0097159,GO:0097366,GO:0097367,GO:0140096,GO:1901265,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901698,GO:1901699,GO:1901700,GO:1901701,GO:1902170 6.3.1.19 0.000000000000000000000000000000000000000000000000000000000739 217.0
PYH3_k127_5539648_2 Cell division protein 48 (CDC48), domain 2 K13525 - - 0.0000000000000000000000000000000000000000000000000006397 205.0
PYH3_k127_5539648_3 Uncharacterized protein family UPF0016 - - - 0.0000000000000000000000224 107.0
PYH3_k127_5539648_4 Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000007542 89.0
PYH3_k127_5539648_5 Transcriptional regulator K05804,K13652,K13653 - - 0.000000000000001715 91.0
PYH3_k127_5539648_6 Fungalysin metallopeptidase (M36) - - - 0.0009008 48.0
PYH3_k127_5542896_0 Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA) K01912 - 6.2.1.30 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001818 494.0
PYH3_k127_5542896_1 TIGRFAM TIGR00725 family protein K06966 - 3.2.2.10 0.00000000000000000000000000009128 119.0
PYH3_k127_5542896_2 Conserved hypothetical ATP binding protein K06883 - - 0.0000000000000002073 81.0
PYH3_k127_5579863_0 histidyl-tRNA aminoacylation K01892 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.21 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006734 319.0
PYH3_k127_5579863_1 DoxX K16937 - 1.8.5.2 0.000297 51.0
PYH3_k127_5604401_0 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 8.393e-222 709.0
PYH3_k127_5604401_1 peroxiredoxin activity - - - 0.0000000000000000000000000000000000000000000000000000000001355 209.0
PYH3_k127_5604401_2 ubiE/COQ5 methyltransferase family - - - 0.00000000000004718 81.0
PYH3_k127_5604401_3 DNA polymerase beta domain protein region - - - 0.000003728 54.0
PYH3_k127_5644631_0 PFAM Acyl-CoA dehydrogenase K00248 - 1.3.8.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001805 360.0
PYH3_k127_5644631_1 Belongs to the class-II aminoacyl-tRNA synthetase family K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.000000000000000000000000000000000000000000000000000000007678 202.0
PYH3_k127_5644631_2 HAD-hyrolase-like - - - 0.00000000000000000000002872 109.0
PYH3_k127_5644631_3 ParE toxin of type II toxin-antitoxin system, parDE K06218 - - 0.000000002553 63.0
PYH3_k127_5653577_0 Fumarase C C-terminus K01679 - 4.2.1.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001071 544.0
PYH3_k127_5653577_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000427 287.0
PYH3_k127_5653577_2 NADH ubiquinone oxidoreductase, 20 Kd subunit K00331,K22159 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000001714 195.0
PYH3_k127_5653577_3 4Fe-4S dicluster domain K00338,K14121,K22164,K22176 - 1.1.98.4,1.5.98.3,1.6.5.3 0.0000000000000000000000000000000000000000005445 168.0
PYH3_k127_5653577_4 exo-alpha-(2->6)-sialidase activity - - - 0.0000000000000000000000000000000000002166 152.0
PYH3_k127_5653577_5 Transcriptional regulator, TrmB - - - 0.000000000000000000001637 105.0
PYH3_k127_5666973_0 Asparagine synthase K01953 - 6.3.5.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005258 419.0
PYH3_k127_5666973_1 Stabilizes TBP binding to an archaeal box-A promoter. Also responsible for recruiting RNA polymerase II to the pre- initiation complex (DNA-TBP-TFIIB) K03124 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003385 390.0
PYH3_k127_5666973_10 Tetratricopeptide repeat - - - 0.0000000000000000000000000000001592 143.0
PYH3_k127_5666973_11 homolog of PrgY (pheromone shutdown protein) - - - 0.00000000000000000000000000008493 125.0
PYH3_k127_5666973_12 rRNA binding K02944 - - 0.000000000006677 68.0
PYH3_k127_5666973_13 Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding K04797 - - 0.000000000371 71.0
PYH3_k127_5666973_14 glutamine amidotransferase - - - 0.000000001522 68.0
PYH3_k127_5666973_2 PFAM Glycosyl transferase family 2 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002462 348.0
PYH3_k127_5666973_3 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC) K03110 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002991 341.0
PYH3_k127_5666973_4 PFAM UDP-N-acetylglucosamine 2-epimerase K01791 GO:0003674,GO:0003824,GO:0008761,GO:0016853,GO:0016854,GO:0016857 5.1.3.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000005327 285.0
PYH3_k127_5666973_5 Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K02683 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001893 283.0
PYH3_k127_5666973_6 PFAM Glycosyl transferase family 2 - - - 0.0000000000000000000000000000000000000000000000000000000000000001825 228.0
PYH3_k127_5666973_7 Adenosine specific kinase K09129 - - 0.000000000000000000000000000000000000000000000000000000000000001553 222.0
PYH3_k127_5666973_8 peptidyl-prolyl cis-trans isomerase K01802,K03775 - 5.2.1.8 0.000000000000000000000000000000000000000000000000000000000000446 220.0
PYH3_k127_5666973_9 Glycosyl transferase 4-like - - - 0.0000000000000000000000000000000000000000000000001325 192.0
PYH3_k127_5706299_0 PFAM Transketolase, thiamine diphosphate binding domain K00615 - 2.2.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001656 355.0
PYH3_k127_5706299_1 Transketolase, pyrimidine binding domain K00615 - 2.2.1.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002897 325.0
PYH3_k127_5706299_2 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway K00616 - 2.2.1.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000007048 284.0
PYH3_k127_5706299_3 Transcriptional regulator - - - 0.0000000000000000000000001 114.0
PYH3_k127_5728616_0 synthetase (ADP forming), alpha K01905,K09181,K22224 - 6.2.1.13 2.225e-209 673.0
PYH3_k127_5728616_1 PFAM SMP-30 Gluconolaconase - - - 0.00000000000000000000000000000000000000000000000003385 208.0
PYH3_k127_5728616_2 PFAM Methylated-DNA- protein -cysteine S-methyltransferase K00567 - 2.1.1.63 0.000000000000000000000000000001347 126.0
PYH3_k127_5728616_3 Hep Hag repeat protein K01190,K01224 - 3.2.1.23,3.2.1.89 0.0000000000001058 87.0
PYH3_k127_5728616_4 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000359 71.0
PYH3_k127_5728616_5 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.00000000001332 73.0
PYH3_k127_5728616_6 Protein of unknown function (DUF1349) - - - 0.000005917 61.0
PYH3_k127_5744260_0 Tripartite tricarboxylate transporter TctA family K08971 - - 0.0000000000000000000000000000009344 132.0
PYH3_k127_5775887_0 Xylose isomerase-like TIM barrel K01151 - 3.1.21.2 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003352 326.0
PYH3_k127_5775887_1 Belongs to the universal ribosomal protein uS9 family K02996 GO:0000462,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0019538,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034645,GO:0034660,GO:0042254,GO:0042274,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000004992 173.0
PYH3_k127_5775887_2 SIS domain K08094 - 5.3.1.27 0.00000000000000000000000000000000000008333 162.0
PYH3_k127_5775887_3 This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly K02871 - - 0.000000000000000000000000000000000252 139.0
PYH3_k127_5775887_4 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates K03058 GO:0000428,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0008270,GO:0030880,GO:0032991,GO:0043167,GO:0043169,GO:0044424,GO:0044464,GO:0046872,GO:0046914,GO:0061695,GO:1902494,GO:1990234 2.7.7.6 0.00000000000000000004118 98.0
PYH3_k127_5775887_5 Belongs to the eukaryotic ribosomal protein eL18 family K02883 - - 0.00000000000000001206 89.0
PYH3_k127_5787354_0 - - - - 0.00000000000000000000004315 101.0
PYH3_k127_5787354_1 - - - - 0.0000000001178 68.0
PYH3_k127_5787354_2 Major Facilitator - - - 0.00008505 48.0
PYH3_k127_5800523_0 Protein of unknown function (DUF521) K09123 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004751 349.0
PYH3_k127_5800523_1 Belongs to the UPF0107 family K09128 - - 0.00000000000000000000000000000000000000000000000000000000001656 216.0
PYH3_k127_5800523_2 AAA domain - - - 0.000000000000000000000000000000000000000002012 166.0
PYH3_k127_5800523_3 exosome subunit K07581 - - 0.0000000000000000000000006745 109.0
PYH3_k127_5800523_4 von Willebrand factor, type A K07114 - - 0.000000000000000000000001109 120.0
PYH3_k127_5800523_5 cheY-homologous receiver domain - - - 0.00000000000000000008938 96.0
PYH3_k127_5800523_6 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.0007582 52.0
PYH3_k127_5806743_0 ATPases associated with a variety of cellular activities K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001043 371.0
PYH3_k127_5806743_1 Dehydrogenase K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002779 351.0
PYH3_k127_5806743_10 - - - - 0.00000000000332 70.0
PYH3_k127_5806743_2 DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair K10747 GO:0000287,GO:0003674,GO:0003824,GO:0003909,GO:0003910,GO:0005488,GO:0005575,GO:0005618,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006266,GO:0006271,GO:0006273,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0016070,GO:0016874,GO:0016886,GO:0022616,GO:0030312,GO:0033554,GO:0034641,GO:0034645,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0046872,GO:0050896,GO:0051103,GO:0051716,GO:0071704,GO:0071944,GO:0090304,GO:0140097,GO:1901360,GO:1901576 6.5.1.1,6.5.1.6,6.5.1.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000005478 275.0
PYH3_k127_5806743_3 Belongs to the enoyl-CoA hydratase isomerase family K01715 - 4.2.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000032 269.0
PYH3_k127_5806743_4 Transport permease protein K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000003837 255.0
PYH3_k127_5806743_5 ABC-2 type transporter K01992 - - 0.0000000000000000000000000000000000000000000000000000000002219 217.0
PYH3_k127_5806743_6 COG0697 Permeases of the drug metabolite transporter (DMT) superfamily - - - 0.00000000000000000000000000000000000000000000000000000005104 207.0
PYH3_k127_5806743_7 Belongs to the peptidase M24B family K01271 - 3.4.13.9 0.000000000000000000000000000000000000000000000142 180.0
PYH3_k127_5806743_8 Part of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends K03540 GO:0000966,GO:0001682,GO:0003674,GO:0003824,GO:0004518,GO:0004519,GO:0004521,GO:0004526,GO:0004540,GO:0004549,GO:0005488,GO:0005575,GO:0006139,GO:0006396,GO:0006399,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0008270,GO:0009987,GO:0010467,GO:0016070,GO:0016787,GO:0016788,GO:0016891,GO:0016893,GO:0030677,GO:0032991,GO:0034470,GO:0034471,GO:0034641,GO:0034660,GO:0043167,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0090305,GO:0090501,GO:0090502,GO:0099116,GO:0140098,GO:0140101,GO:1901360,GO:1902494,GO:1902555,GO:1905348,GO:1990904 3.1.26.5 0.0000000000000000000007497 99.0
PYH3_k127_5806743_9 Belongs to the eukaryotic ribosomal protein eS17 family K02962 GO:0000028,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.00000000000000005552 83.0
PYH3_k127_585515_0 transferase activity, transferring glycosyl groups K01186,K01371,K20276 - 3.2.1.18,3.4.22.38 0.000000000000000003523 98.0
PYH3_k127_5866339_0 Protein of unknown function (DUF1246) K06863 - 6.3.4.23 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004478 536.0
PYH3_k127_5866339_1 FAD linked oxidases, C-terminal domain K00803 - 2.5.1.26 0.0000000000000000000000000000000000000000000000000000003899 201.0
PYH3_k127_5866339_2 COG0530 Ca2 Na antiporter K07301 - - 0.000000000000000000000000000000000000001291 160.0
PYH3_k127_5910115_0 Ribosomal protein L11 methyltransferase (PrmA) K07579 - - 0.000000000000000000000000000000000000000000000000000000007434 207.0
PYH3_k127_5910115_1 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000449 123.0
PYH3_k127_5910115_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Helpful for the interaction of the exosome with A-poor RNAs K07573 - - 0.0000001449 55.0
PYH3_k127_5916738_0 Belongs to the ABC transporter superfamily K11072 - 3.6.3.31 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003036 342.0
PYH3_k127_5916738_1 Bacterial extracellular solute-binding protein - - - 0.0000000000003514 77.0
PYH3_k127_6014285_0 ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S proteasome association which triggers gate opening, and supports translocation of unfolded substrates K03420 - - 0.000000000000000000000000000000000000000000000001069 177.0
PYH3_k127_6014285_1 FKBP-type peptidyl-prolyl cis-trans isomerase - - - 0.00000000000000000000000000000007559 136.0
PYH3_k127_6014285_3 Glycosyl transferase family 21 - - - 0.000002566 51.0
PYH3_k127_6014285_4 - - - - 0.0009288 51.0
PYH3_k127_6022777_0 Arginase family K01476,K01480 GO:0003674,GO:0003824,GO:0006576,GO:0006595,GO:0006596,GO:0006807,GO:0008150,GO:0008152,GO:0008216,GO:0008295,GO:0008783,GO:0009058,GO:0009308,GO:0009309,GO:0009987,GO:0016787,GO:0016810,GO:0016813,GO:0034641,GO:0042401,GO:0044106,GO:0044237,GO:0044249,GO:0044271,GO:0071704,GO:0097164,GO:1901564,GO:1901566,GO:1901576 3.5.3.1,3.5.3.11 0.00000000000000000000000000000000000000000000000000000000000000000000000000000894 273.0
PYH3_k127_6022777_1 Functions by promoting the formation of the first peptide bond K03263 - - 0.000000000000000000000000000000000000000000002053 170.0
PYH3_k127_6022777_2 PFAM Pre-mRNA processing ribonucleoprotein, binding K14564 - - 0.0000000000000000000000000003105 117.0
PYH3_k127_6022777_3 Multi-copper - - - 0.000006933 56.0
PYH3_k127_6022777_4 Acetyltransferase (GNAT) domain K03823 - 2.3.1.183 0.0003727 51.0
PYH3_k127_6022777_5 Sterol carrier protein domain - - - 0.0009281 50.0
PYH3_k127_603719_0 Toprim domain K02316 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008869 398.0
PYH3_k127_603719_1 metal ion binding - - - 0.00000000000000000002003 100.0
PYH3_k127_603719_2 Belongs to the UPF0235 family K09131 - - 0.00000000002754 69.0
PYH3_k127_603719_3 protein conserved in archaea K09723 - - 0.00003448 53.0
PYH3_k127_6042043_0 Pfam:DUF650 - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008391 481.0
PYH3_k127_6042043_1 Responsible for synthesis of pseudouridine from uracil- 54 and uracil-55 in the psi GC loop of transfer RNAs K07583 - 5.4.99.25 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001122 330.0
PYH3_k127_6042043_2 Elongator protein 3, MiaB family, Radical SAM - - - 0.000000000000000000000000000000000000000000000000000000000000000000000002936 254.0
PYH3_k127_6042043_3 Helix-hairpin-helix motif K07572 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005523 247.0
PYH3_k127_6042043_4 PFAM Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000004606 156.0
PYH3_k127_6042043_5 ADP-ribose pyrophosphatase K03574 - 3.6.1.55 0.000000000000000000000000000725 130.0
PYH3_k127_6042043_6 Belongs to the eukaryotic ribosomal protein eL21 family K02889 - - 0.000000000000000000000002111 108.0
PYH3_k127_6042043_7 RNA polymerase K03051 - 2.7.7.6 0.00000000000000000002378 96.0
PYH3_k127_6042043_8 PFAM regulatory protein, ArsR - - - 0.0000000000002202 76.0
PYH3_k127_6042043_9 PFAM Archaeal ATPase K03524,K06921 - 6.3.4.15 0.0000000005169 70.0
PYH3_k127_6067524_0 PFAM Cytidine and deoxycytidylate deaminase zinc-binding region K01493 - 3.5.4.12 0.000000000000001664 87.0
PYH3_k127_6067524_1 Winged helix DNA-binding domain - - - 0.000000000000003721 83.0
PYH3_k127_6067524_2 COGs COG2885 Outer membrane protein and related peptidoglycan-associated (lipo)protein K02557,K03286 - - 0.00000000000002796 86.0
PYH3_k127_6067564_0 Peptidase M16 domain protein K07263 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001923 325.0
PYH3_k127_6067564_1 Insulinase (Peptidase family M16) - - - 0.00000000000001549 87.0
PYH3_k127_6084445_0 Dimerisation domain - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000001671 268.0
PYH3_k127_6084445_2 Protein of unknown function (DUF504) K09715 - - 0.00003588 48.0
PYH3_k127_6095439_0 Sodium/hydrogen exchanger family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000001482 260.0
PYH3_k127_6119777_0 ATPase, P-type (transporting), HAD superfamily, subfamily IC K01537 - 3.6.3.8 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001011 539.0
PYH3_k127_6119777_1 Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val) K01265 - 3.4.11.18 0.000000000000000000000000000000000000000000000000000000000000000000296 248.0
PYH3_k127_6119777_2 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine K07566 GO:0000166,GO:0003674,GO:0005488,GO:0005524,GO:0008144,GO:0017076,GO:0030554,GO:0032553,GO:0032555,GO:0032559,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0097159,GO:0097367,GO:1901265,GO:1901363 2.7.7.87 0.000000000000000000000000000000003262 138.0
PYH3_k127_6119777_3 Uncharacterized ArCR, COG1888 K09732 - - 0.00000000000000000000000001121 121.0
PYH3_k127_6119777_5 Involved in DNA repair and in homologous recombination. Binds and assemble on single-stranded DNA to form a nucleoprotein filament. Hydrolyzes ATP in a ssDNA-dependent manner and promotes DNA strand exchange between homologous DNA molecules K04483 - - 0.0000000000000000000001136 97.0
PYH3_k127_6119777_6 Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds directly to 7S RNA and mediates binding of the 54 kDa subunit of the SRP K03105 - - 0.0000000000000001279 86.0
PYH3_k127_6119777_7 Acetyltransferase (GNAT) domain - - - 0.0000000000002571 83.0
PYH3_k127_6119777_8 Domain of unknown function (DUF4304) - - - 0.0000000002167 72.0
PYH3_k127_6119777_9 HEPN domain - - - 0.000000002143 63.0
PYH3_k127_617575_0 DEAD H associated K03724 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 448.0
PYH3_k127_617575_1 Belongs to the short-chain dehydrogenases reductases (SDR) family - - - 0.000000000000000000000000000000000000000000000000001088 203.0
PYH3_k127_6237022_0 Belongs to the peptidase S16 family K04076 - 3.4.21.53 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001295 552.0
PYH3_k127_6237022_1 One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit K02906 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003842 420.0
PYH3_k127_6237022_10 Binds to 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome K02892 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0016043,GO:0019538,GO:0022607,GO:0022613,GO:0022618,GO:0022625,GO:0022626,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.0000000000000000000001103 111.0
PYH3_k127_6237022_2 Binds the lower part of the 30S subunit head K02982 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001756 284.0
PYH3_k127_6237022_3 Ribosomal Proteins L2, C-terminal domain K02886 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000000000000000000000002447 261.0
PYH3_k127_6237022_4 Forms part of the polypeptide exit tunnel K02930 GO:0002181,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0015934,GO:0019538,GO:0022625,GO:0022626,GO:0032991,GO:0034641,GO:0034645,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0071704,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000000918 214.0
PYH3_k127_6237022_5 Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA K02965 GO:0000028,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006996,GO:0008150,GO:0009987,GO:0015935,GO:0016043,GO:0022607,GO:0022613,GO:0022618,GO:0022626,GO:0022627,GO:0032991,GO:0034622,GO:0042254,GO:0042255,GO:0042274,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043933,GO:0044085,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0065003,GO:0070925,GO:0071826,GO:0071840,GO:1990904 - 0.000000000000000000000000000000000000000000000003961 176.0
PYH3_k127_6237022_6 The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome K02890 - - 0.00000000000000000000000000000000001745 139.0
PYH3_k127_6237022_7 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000005799 131.0
PYH3_k127_6237022_8 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000006676 132.0
PYH3_k127_6237022_9 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000007326 126.0
PYH3_k127_6254845_0 Domain of unknown function (DUF1877) - - - 0.00000000000000000000007964 112.0
PYH3_k127_6254845_1 Peptidase S8 and S53 subtilisin kexin sedolisin - - - 0.000001794 59.0
PYH3_k127_6254845_2 GXGXG motif - - - 0.0008195 42.0
PYH3_k127_6430488_0 tRNA-splicing ligase RtcB K14415 GO:0000166,GO:0000394,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003972,GO:0005488,GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008380,GO:0008452,GO:0009987,GO:0010467,GO:0016070,GO:0016874,GO:0016886,GO:0017076,GO:0019001,GO:0019002,GO:0030145,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0034641,GO:0036094,GO:0043167,GO:0043168,GO:0043169,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0046872,GO:0046914,GO:0071704,GO:0090304,GO:0097159,GO:0097367,GO:0140098,GO:1901265,GO:1901360,GO:1901363 6.5.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004667 610.0
PYH3_k127_6430488_1 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000001861 284.0
PYH3_k127_6430488_2 PFAM ABC-2 type transporter K01992 - - 0.00000000000002105 87.0
PYH3_k127_6430488_3 ABC-2 type transporter K01992 - - 0.000000000005116 76.0
PYH3_k127_6442755_0 methyltransferase small K00564 - 2.1.1.172 0.0000000000000000000000000000000000000000000000000000002917 201.0
PYH3_k127_6442755_1 Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits K02952 - - 0.00000000000000000000000000000000000000000001115 169.0
PYH3_k127_6442755_2 One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit K02986 GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006417,GO:0006450,GO:0008150,GO:0009889,GO:0009891,GO:0009893,GO:0010468,GO:0010556,GO:0010557,GO:0010604,GO:0010608,GO:0010628,GO:0015935,GO:0019222,GO:0019843,GO:0031323,GO:0031325,GO:0031326,GO:0031328,GO:0032268,GO:0032270,GO:0032991,GO:0034248,GO:0034250,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044446,GO:0044464,GO:0045727,GO:0045903,GO:0048518,GO:0048522,GO:0050789,GO:0050794,GO:0051171,GO:0051173,GO:0051246,GO:0051247,GO:0060255,GO:0065007,GO:0065008,GO:0080090,GO:0097159,GO:1901363,GO:1990904,GO:2000112 - 0.0000000000000000000000000000000000000000003884 164.0
PYH3_k127_6447038_0 AMP-binding enzyme K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002719 332.0
PYH3_k127_6447038_1 Belongs to the enoyl-CoA hydratase isomerase family K15016 - 1.1.1.35,4.2.1.17 0.0000000000003316 71.0
PYH3_k127_6502868_0 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004648 394.0
PYH3_k127_6502868_1 Fic/DOC family - - - 0.000000000000002934 82.0
PYH3_k127_6511637_0 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal alpha chain is a catalytic subunit K02117 - 3.6.3.14,3.6.3.15 4.038e-249 784.0
PYH3_k127_6511637_1 Produces ATP from ADP in the presence of a proton gradient across the membrane. The archaeal beta chain is a regulatory subunit K02118 - - 4.469e-230 719.0
PYH3_k127_6511637_2 Produces ATP from ADP in the presence of a proton gradient across the membrane K02120 - - 0.00000000000000000000000000000000004244 137.0
PYH3_k127_6511637_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000001181 136.0
PYH3_k127_6511637_4 Produces ATP from ADP in the presence of a proton gradient across the membrane K02122 - - 0.0000000000000000000008535 97.0
PYH3_k127_6538661_0 General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) K01006 - 2.7.9.1 1.108e-294 925.0
PYH3_k127_6538661_1 PFAM blue (type 1) copper domain protein K00368 - 1.7.2.1 0.00000000000000000000000000000000000000008864 162.0
PYH3_k127_6538661_2 K homology RNA-binding domain K06961 - - 0.000000000000000000000000000000000000005589 149.0
PYH3_k127_6550763_0 Protein of unknown function, DUF255 K06888 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003057 625.0
PYH3_k127_6550763_1 ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000005567 251.0
PYH3_k127_6550763_2 Bacterial transferase hexapeptide (six repeats) - - - 0.00000000000000000000000000000000000187 155.0
PYH3_k127_6550763_3 Thioesterase-like superfamily K07107 - - 0.00000000000000000000000000003118 121.0
PYH3_k127_6550763_4 COG0842 ABC-type multidrug transport system, permease component K01992 - - 0.00000000000000000274 98.0
PYH3_k127_6550763_5 ubiE/COQ5 methyltransferase family - - - 0.000001566 61.0
PYH3_k127_6550763_6 helix_turn_helix ASNC type K03719 - - 0.000004918 59.0
PYH3_k127_6624616_0 Putative modulator of DNA gyrase K03592 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001482 383.0
PYH3_k127_6624616_1 modulator of DNA gyrase K03568 - - 0.000000000000000000000000000000000000000000000000000000000000000002603 229.0
PYH3_k127_6624616_2 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03238 - - 0.00000000000000000000000000000000000000000000000000000000000189 218.0
PYH3_k127_6624616_3 SMART Peptidase A22, presenilin signal peptide - - - 0.000000000000000000000000000000000000000000000000000000003923 217.0
PYH3_k127_6624616_4 Metallophosphoesterase, calcineurin superfamily K07096 - - 0.0000000000000000000000000000000000000000002008 167.0
PYH3_k127_6624616_5 PFAM ribosomal protein S8E K02995 GO:0000462,GO:0003674,GO:0003735,GO:0005198,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0030490,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000000000007099 156.0
PYH3_k127_6624616_6 Major facilitator superfamily - - - 0.000000000000000000000000000004353 135.0
PYH3_k127_6624616_7 Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates K01937 - 6.3.4.2 0.000000000000000004974 84.0
PYH3_k127_6665477_0 Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA K04801 GO:0005575,GO:0005622,GO:0005623,GO:0005657,GO:0005663,GO:0005694,GO:0006139,GO:0006259,GO:0006260,GO:0006261,GO:0006281,GO:0006725,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0032991,GO:0033554,GO:0034641,GO:0034645,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044422,GO:0044424,GO:0044427,GO:0044446,GO:0044464,GO:0046483,GO:0050896,GO:0051716,GO:0071704,GO:0090304,GO:1901360,GO:1901576 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008378 412.0
PYH3_k127_6665477_1 Radical SAM K04069 - 1.97.1.4 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000601 397.0
PYH3_k127_6665477_2 Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1 K00946 - 2.7.4.16 0.0000000000000000000000000000000000000000000000000000000000001472 226.0
PYH3_k127_6665477_3 vacuolar iron transporter - GO:0000041,GO:0003674,GO:0005215,GO:0005384,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005773,GO:0005774,GO:0006810,GO:0006811,GO:0006812,GO:0006828,GO:0006873,GO:0006875,GO:0006879,GO:0006880,GO:0008150,GO:0008324,GO:0009987,GO:0010035,GO:0010038,GO:0010039,GO:0015075,GO:0015318,GO:0016020,GO:0019725,GO:0022857,GO:0022890,GO:0030001,GO:0030003,GO:0030026,GO:0031090,GO:0034220,GO:0042221,GO:0042592,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044437,GO:0044444,GO:0044446,GO:0044464,GO:0046873,GO:0046915,GO:0046916,GO:0048878,GO:0050801,GO:0050896,GO:0051179,GO:0051234,GO:0051235,GO:0051238,GO:0051641,GO:0051651,GO:0051716,GO:0055065,GO:0055071,GO:0055072,GO:0055076,GO:0055080,GO:0055082,GO:0055085,GO:0065007,GO:0065008,GO:0070887,GO:0071241,GO:0071248,GO:0071281,GO:0071421,GO:0097577,GO:0098588,GO:0098655,GO:0098660,GO:0098662,GO:0098771,GO:0098805 - 0.0000000000000000000000000125 118.0
PYH3_k127_6665477_4 Thermophilic metalloprotease (M29) - - - 0.0000000000000000000004736 103.0
PYH3_k127_6701197_0 3-octaprenyl-4-hydroxybenzoate carboxy-lyase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001352 435.0
PYH3_k127_6701197_1 Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) K01885 - 6.1.1.17 0.0000000001483 63.0
PYH3_k127_6706492_0 Aspartate-ammonia ligase K01914 GO:0003674,GO:0003824,GO:0004071,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006082,GO:0006520,GO:0006528,GO:0006529,GO:0006807,GO:0006950,GO:0006974,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009987,GO:0016053,GO:0016211,GO:0016874,GO:0016879,GO:0016880,GO:0019752,GO:0032787,GO:0033554,GO:0034641,GO:0042802,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0044424,GO:0044444,GO:0044464,GO:0046394,GO:0050896,GO:0051716,GO:0071704,GO:0072330,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 6.3.1.1 6.281e-215 670.0
PYH3_k127_6706492_1 B3/4 domain K01890 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006139,GO:0006399,GO:0006412,GO:0006418,GO:0006432,GO:0006518,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009328,GO:0009987,GO:0010467,GO:0016070,GO:0019538,GO:0019752,GO:0032991,GO:0034641,GO:0034645,GO:0034660,GO:0043038,GO:0043039,GO:0043043,GO:0043170,GO:0043436,GO:0043603,GO:0043604,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0071704,GO:0090304,GO:1901360,GO:1901564,GO:1901566,GO:1901576,GO:1902494 6.1.1.20 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003405 466.0
PYH3_k127_6706492_2 Putative esterase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007208 322.0
PYH3_k127_6706492_3 PrcB C-terminal - - - 0.00001179 55.0
PYH3_k127_6711045_0 PFAM TPR repeat-containing protein - - - 0.00000000000000000000000000000005883 143.0
PYH3_k127_6711045_1 Helix-turn-helix XRE-family like proteins K03627 - - 0.000000000000000000000000000008882 124.0
PYH3_k127_6711045_2 protein conserved in archaea - - - 0.0000000000000007425 87.0
PYH3_k127_6711045_3 Histidine biosynthesis protein K01814 - 5.3.1.16 0.0004328 50.0
PYH3_k127_6742252_0 Catalyzes the NAD(P)H-dependent reduction of dihydroxyacetonephosphate (DHAP or glycerone phosphate) to glycerol 1-phosphate (G1P). The G1P thus generated is used as the glycerophosphate backbone of phospholipids in the cellular membranes of Archaea K00096 - 1.1.1.261 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001359 399.0
PYH3_k127_6742252_1 PFAM Tetratricopeptide repeat - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002433 375.0
PYH3_k127_6742252_2 Serine threonine protein kinase involved in cell cycle control K07178 - 2.7.11.1 0.000000002028 63.0
PYH3_k127_6743475_0 hydrolase activity, acting on ester bonds - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003029 279.0
PYH3_k127_6743475_1 PFAM cytochrome c biogenesis protein, transmembrane region - - - 0.0000000005745 71.0
PYH3_k127_6743475_2 InterPro IPR011467 - - - 0.0000000085 65.0
PYH3_k127_6743475_3 Short C-terminal domain K08982 - - 0.00000004434 59.0
PYH3_k127_6743475_4 membrane-associated protein domain - - - 0.000001406 57.0
PYH3_k127_6743475_5 alginic acid biosynthetic process K01729 - 4.2.2.3 0.00003136 57.0
PYH3_k127_68384_0 Isocitrate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001312 409.0
PYH3_k127_68384_1 Citrate synthase, C-terminal domain K01647 - 2.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006513 411.0
PYH3_k127_68384_2 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01704 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000000000000000000000007927 243.0
PYH3_k127_68384_3 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.0000000000000000000000000000000000000000000000000005356 189.0
PYH3_k127_6901493_0 Hydroxymethylglutaryl-CoA reductase, degradative K00054 - 1.1.1.88 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001711 497.0
PYH3_k127_6964246_0 carboxyl transferase K01966 - 2.1.3.15,6.4.1.3 8.282e-209 655.0
PYH3_k127_6964246_1 PFAM Conserved carboxylase region K01571,K01960 - 4.1.1.3,6.4.1.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003289 572.0
PYH3_k127_6990617_0 Cell division protein 48 (CDC48), domain 2 K13525 - - 2.035e-320 994.0
PYH3_k127_6990617_1 Catalyzes the phosphorylation of (R)-mevalonate (MVA) to (R)-mevalonate 5-phosphate (MVAP). Functions in the mevalonate (MVA) pathway leading to isopentenyl diphosphate (IPP), a key precursor for the biosynthesis of isoprenoid compounds such as archaeal membrane lipids K00869 GO:0003674,GO:0003824,GO:0004496,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006084,GO:0006139,GO:0006163,GO:0006629,GO:0006637,GO:0006644,GO:0006720,GO:0006725,GO:0006732,GO:0006753,GO:0006790,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008202,GO:0008299,GO:0008610,GO:0008654,GO:0009058,GO:0009117,GO:0009150,GO:0009240,GO:0009259,GO:0009987,GO:0016125,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0019287,GO:0019637,GO:0019693,GO:0033865,GO:0033875,GO:0034032,GO:0034641,GO:0035383,GO:0043603,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046490,GO:0051186,GO:0055086,GO:0071704,GO:0072521,GO:0090407,GO:1901135,GO:1901360,GO:1901564,GO:1901576,GO:1901615 2.7.1.36 0.0000000000000000000000000000000000000000000001818 175.0
PYH3_k127_6990617_2 Belongs to the small heat shock protein (HSP20) family K13993 - - 0.00000000000000000000211 100.0
PYH3_k127_6990617_3 ZPR1-related zinc finger protein K06874 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 - 0.000000000000000007751 87.0
PYH3_k127_6994783_0 Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue K00809 - 2.5.1.46 0.00000000000000000000000000000000000000000000000000000000000000000000000000001049 277.0
PYH3_k127_6994783_1 - - - - 0.00000005062 56.0
PYH3_k127_7020244_0 Possesses two activities a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase K02323 - 2.7.7.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008081 406.0
PYH3_k127_7030713_0 PFAM GCN5-related N-acetyltransferase - - - 0.0000000000000000000000000000007814 130.0
PYH3_k127_7030713_1 von Willebrand factor, type A K07114 - - 0.000000000000000000000001403 120.0
PYH3_k127_7030713_2 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.000000000000000001721 100.0
PYH3_k127_7030713_3 peptidase M36 K01417 - - 0.000004362 60.0
PYH3_k127_7030713_4 repeat protein - - - 0.00002364 57.0
PYH3_k127_7038033_0 COG1233 Phytoene dehydrogenase and related proteins K10027,K20611 - 1.3.99.26,1.3.99.28,1.3.99.29,1.3.99.31,1.3.99.37 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001657 591.0
PYH3_k127_7038033_1 Phytoene squalene synthetase K02291 - 2.5.1.32,2.5.1.99 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000002036 296.0
PYH3_k127_7038033_2 COG0382 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases K20616 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000002088 263.0
PYH3_k127_7038033_3 NmrA-like family - - - 0.00000000000000000000000000000000000000000000000000000000000000000002878 235.0
PYH3_k127_7038033_4 COGs COG2335 Secreted and surface protein containing fasciclin-like repeats - - - 0.0000000000000000000000000000000000000000000000001179 181.0
PYH3_k127_7038033_5 - - - - 0.000000000000000000000000000000000000000001803 160.0
PYH3_k127_7038033_6 protein conserved in bacteria - - - 0.000000000000000000000000000000000000002574 154.0
PYH3_k127_7038033_7 PFAM TspO MBR family K05770 - - 0.0000000000000000000000000000000000001411 147.0
PYH3_k127_7038033_8 - - - - 0.00000000000000334 81.0
PYH3_k127_7083082_0 Asparaginase K13051 - 3.4.19.5 0.00000000000000000000000000000000000000000000000000000000000000004603 233.0
PYH3_k127_7083082_1 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.0000000000000000000000000000000000000000000000000000000000000121 225.0
PYH3_k127_7083082_2 protein conserved in archaea - - - 0.00000000000000000000001936 108.0
PYH3_k127_7083082_3 Low molecular weight phosphatase family K03741 - 1.20.4.1 0.00000000000000000000003533 105.0
PYH3_k127_7083082_4 daunorubicin resistance ABC transporter K01990 - - 0.0000000000061 68.0
PYH3_k127_7133958_0 Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) K01588 - 5.4.99.18 0.00000000000000000000000000000000000000000000001269 181.0
PYH3_k127_7133958_1 Lrp/AsnC ligand binding domain - - - 0.0000000000000000000000000000000006722 131.0
PYH3_k127_7133958_2 Belongs to the carbohydrate kinase PfkB family K22026 GO:0000287,GO:0003674,GO:0003824,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005975,GO:0006139,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0008906,GO:0009058,GO:0009117,GO:0009165,GO:0009987,GO:0016301,GO:0016310,GO:0016740,GO:0016772,GO:0016773,GO:0018130,GO:0019200,GO:0019205,GO:0019206,GO:0019438,GO:0019637,GO:0034641,GO:0034654,GO:0043167,GO:0043169,GO:0044237,GO:0044238,GO:0044249,GO:0044262,GO:0044271,GO:0044281,GO:0044424,GO:0044464,GO:0046483,GO:0046835,GO:0046872,GO:0055086,GO:0071704,GO:0090407,GO:1901293,GO:1901360,GO:1901362,GO:1901576 2.7.1.213,2.7.1.73 0.00000000002238 65.0
PYH3_k127_7133958_3 SMART Parallel beta-helix repeat - - - 0.000000249 61.0
PYH3_k127_7133958_4 - - - - 0.000001283 56.0
PYH3_k127_7151825_0 Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange K04484 - - 0.0000000000000000000000000000000000000000000000000000000002099 211.0
PYH3_k127_7151825_1 Belongs to the FPP GGPP synthase family K13787 - 2.5.1.1,2.5.1.10,2.5.1.29 0.00000000000000000001132 104.0
PYH3_k127_7151825_2 Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP) K01823 - 5.3.3.2 0.0001282 46.0
PYH3_k127_7151825_3 Circadian clock protein KaiC K06945 - - 0.0002248 52.0
PYH3_k127_7158_0 Dehydrogenase E1 component K00161,K00166 - 1.2.4.1,1.2.4.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005319 387.0
PYH3_k127_7158_1 Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives K03644 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006082,GO:0006464,GO:0006629,GO:0006631,GO:0006633,GO:0006732,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008610,GO:0009058,GO:0009106,GO:0009107,GO:0009108,GO:0009249,GO:0009987,GO:0010467,GO:0016053,GO:0016740,GO:0016782,GO:0016783,GO:0016992,GO:0018065,GO:0018130,GO:0018193,GO:0018205,GO:0019538,GO:0019752,GO:0032787,GO:0036211,GO:0043170,GO:0043412,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044260,GO:0044267,GO:0044272,GO:0044281,GO:0044283,GO:0044424,GO:0044464,GO:0046394,GO:0046483,GO:0051186,GO:0051188,GO:0051604,GO:0070283,GO:0071704,GO:0072330,GO:1901360,GO:1901362,GO:1901564,GO:1901576 2.8.1.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000464 371.0
PYH3_k127_7158_2 PFAM 4Fe-4S ferredoxin, iron-sulfur binding domain protein K03855 - - 0.00000001023 56.0
PYH3_k127_7203931_0 Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair K18882 - - 0.000000000000000000000000000000000000000000000000000000000000000000003233 248.0
PYH3_k127_7203931_1 Belongs to the CDP-alcohol phosphatidyltransferase class-I family K17884 - 2.7.8.39 0.00000000000000000000000000000000000000000001958 175.0
PYH3_k127_7203931_2 Broad-specificity nucleoside monophosphate (NMP) kinase that catalyzes the reversible transfer of the terminal phosphate group between nucleoside triphosphates and monophosphates K18532 - 2.7.4.3 0.0000000000000000000000000000000000003033 145.0
PYH3_k127_7219231_0 4Fe-4S single cluster domain K06937 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 536.0
PYH3_k127_7219231_1 Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3-diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di-O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains K17830 - 1.3.1.101,1.3.7.11 0.00000000000000000000000000000000000000000002291 166.0
PYH3_k127_7219231_2 4Fe-4S ferredoxin iron-sulfur binding domain protein - - - 0.00000000000001733 78.0
PYH3_k127_7220796_0 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000006349 136.0
PYH3_k127_7231128_0 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K09482 - 6.3.5.7 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007565 353.0
PYH3_k127_7231128_1 Winged helix-turn-helix DNA-binding - - - 0.000001924 62.0
PYH3_k127_7261847_0 Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate K01703 - 4.2.1.33,4.2.1.35 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008559 334.0
PYH3_k127_7261847_1 Proline dehydrogenase K00318 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000002364 256.0
PYH3_k127_7261847_2 Nucleotidyltransferase domain - - - 0.00000000000000000000000000000000000000000000000000000002292 206.0
PYH3_k127_7261847_3 UbiA prenyltransferase family K02257 - 2.5.1.141 0.000000000000000000000000000000000000000000000001831 184.0
PYH3_k127_7261847_4 Oxidoreductase FAD-binding domain - - - 0.00000000000000000000000000000000000000425 157.0
PYH3_k127_7261847_5 - - - - 0.0000000000000000003849 93.0
PYH3_k127_7271046_0 Type II/IV secretion system protein - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001267 415.0
PYH3_k127_7311300_0 Belongs to the UDP-N-acetylglucosamine 2-epimerase family K01791,K13019 - 5.1.3.14,5.1.3.23 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 452.0
PYH3_k127_7311300_1 Belongs to the UDP-glucose GDP-mannose dehydrogenase family K02472 - 1.1.1.336 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001042 337.0
PYH3_k127_7311300_2 Oxidoreductase domain protein K18855 - 1.1.1.374 0.00000000000000000000000000000000000000000000000000000000000000004577 229.0
PYH3_k127_7311300_3 Pfam:Methyltransf_26 K02493 - 2.1.1.297 0.0000000000000000000000004182 114.0
PYH3_k127_7311300_4 membrane protein (homolog of Drosophila rhomboid) - - - 0.0000000000000005358 88.0
PYH3_k127_7311713_0 Methylmalonyl-CoA mutase K01847,K01848 - 5.4.99.2 7.149e-202 639.0
PYH3_k127_7311713_1 PFAM AIR synthase related protein K01933 - 6.3.3.1 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001099 341.0
PYH3_k127_7311713_2 PFAM Coenzyme A transferase K01040 - 2.8.3.12 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 310.0
PYH3_k127_7311713_3 PFAM Coenzyme A transferase K01039 - 2.8.3.12 0.000000000000000000000000000000000000000000000000000000000000000000001641 247.0
PYH3_k127_7311713_4 Rubrerythrin - - - 0.0000000000000000000000000000000000000000000000005934 191.0
PYH3_k127_7311713_5 Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit K02427 - 2.1.1.166 0.00000000001606 77.0
PYH3_k127_7353927_0 class II (D K and N) K01893 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 6.1.1.22 0.00000000000000000000000000000000000000000000000000000000000000000000000000005063 266.0
PYH3_k127_7353927_1 Pyruvoyl-dependent arginine decarboxylase K02626 - 4.1.1.19 0.00000000000000000000000000000000000000000000000001348 184.0
PYH3_k127_7353927_2 FR47-like protein K03789 - 2.3.1.128 0.0000000000001108 77.0
PYH3_k127_7353927_3 - - - - 0.0000000000005342 78.0
PYH3_k127_7353927_4 deoxyhypusine monooxygenase activity - - - 0.00000000003232 72.0
PYH3_k127_7397507_0 Metallopeptidase family M24 K01271 - 3.4.13.9 0.0000000000000000000000000000000000000000000000000000000000001088 218.0
PYH3_k127_7397507_1 Acetyltransferase (GNAT) domain - - - 0.000000000000000000000000000000000007483 144.0
PYH3_k127_7400026_0 May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine K01251 - 3.3.1.1 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005953 528.0
PYH3_k127_7400026_1 Bacterial extracellular solute-binding proteins, family 5 Middle K02035 - - 0.00000000000000000000009827 115.0
PYH3_k127_7400026_2 Putative Phosphatase - - - 0.0000001042 59.0
PYH3_k127_7408315_0 Helix-hairpin-helix domain K02347 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004141 538.0
PYH3_k127_7408315_1 Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine K12960 - 3.5.4.28,3.5.4.31 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008763 409.0
PYH3_k127_7408315_10 COG1549 Queuine tRNA-ribosyltransferases, contain PUA domain K07557 - 2.6.1.97 0.0000000001122 70.0
PYH3_k127_7408315_2 PFAM sodium hydrogen exchanger - - - 0.00000000000000000000000000000000000000000000000000000000005671 221.0
PYH3_k127_7408315_3 Catalyzes a salvage reaction resulting in the formation of IMP that is energically less costly than de novo synthesis K00759 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.4.2.7 0.0000000000000000000000000000000000000000000000000000001574 201.0
PYH3_k127_7408315_4 PFAM GvpD gas vesicle - - - 0.0000000000000000000000000000000000000000000000000000004496 213.0
PYH3_k127_7408315_5 Phosphorylase superfamily K00772 GO:0000096,GO:0000097,GO:0003674,GO:0003824,GO:0004731,GO:0006082,GO:0006139,GO:0006144,GO:0006168,GO:0006520,GO:0006555,GO:0006725,GO:0006790,GO:0006807,GO:0008150,GO:0008152,GO:0008652,GO:0009058,GO:0009066,GO:0009067,GO:0009086,GO:0009112,GO:0009113,GO:0009987,GO:0016053,GO:0016740,GO:0016757,GO:0016763,GO:0017061,GO:0017144,GO:0018130,GO:0019438,GO:0019509,GO:0019752,GO:0034641,GO:0034654,GO:0042440,GO:0043094,GO:0043096,GO:0043101,GO:0043102,GO:0043436,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044272,GO:0044281,GO:0044283,GO:0046083,GO:0046084,GO:0046112,GO:0046148,GO:0046394,GO:0046483,GO:0055086,GO:0071265,GO:0071267,GO:0071704,GO:0072521,GO:0072522,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901605,GO:1901607 2.4.2.28 0.00000000000000000000000000000000000000000000000000001008 198.0
PYH3_k127_7408315_6 Belongs to the Nudix hydrolase family - - - 0.00000000000000001568 91.0
PYH3_k127_7408315_7 Helix-turn-helix domain - - - 0.0000000000000003769 83.0
PYH3_k127_7408315_8 transcriptional regulators - - - 0.00000000000000851 79.0
PYH3_k127_7408315_9 Protein of unknown function (DUF835) K01937,K02488 - 2.7.7.65,6.3.4.2 0.0000000000002577 76.0
PYH3_k127_7465229_0 Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates K00179 - 1.2.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003758 385.0
PYH3_k127_7465229_1 TIGRFAM indolepyruvate ferredoxin oxidoreductase, beta subunit K00180 - 1.2.7.8 0.0000000000000000000000000000000007212 147.0
PYH3_k127_7469310_0 Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP K00858 - 2.7.1.23 0.0000000000000000000000000000000000000000000000000002717 198.0
PYH3_k127_7469310_1 - - - - 0.000000000000000000000000000000000000000000000000008141 187.0
PYH3_k127_7469310_2 Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). The GatDE system is specific for glutamate and does not act on aspartate K03330 GO:0003674,GO:0003824,GO:0006082,GO:0006139,GO:0006399,GO:0006520,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0016070,GO:0016874,GO:0016879,GO:0016884,GO:0019752,GO:0034641,GO:0034660,GO:0043038,GO:0043039,GO:0043170,GO:0043436,GO:0044237,GO:0044238,GO:0044281,GO:0046483,GO:0050567,GO:0070681,GO:0071704,GO:0090304,GO:0140098,GO:0140101,GO:1901360,GO:1901564 6.3.5.7 0.0000001956 54.0
PYH3_k127_7512481_0 Belongs to the class-I aminoacyl-tRNA synthetase family K04566 - 6.1.1.6 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001516 481.0
PYH3_k127_7512481_1 - - - - 0.000000000004007 79.0
PYH3_k127_7512481_2 Acetyl xylan esterase (AXE1) - - - 0.000000001097 70.0
PYH3_k127_7518410_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001981 489.0
PYH3_k127_7518410_1 TIGRFAM oligopeptide dipeptide ABC transporter, ATPase subunit K02032,K10823 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001595 407.0
PYH3_k127_7518410_2 Oligopeptide/dipeptide transporter, C-terminal region K02031 - - 0.00000000000000000000000000000000000000000000000000000000000001189 228.0
PYH3_k127_7607447_0 Directs the termination of nascent peptide synthesis (translation) in response to the termination codons UAA, UAG and UGA K03265 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001539 456.0
PYH3_k127_7624494_0 TIGRFAM methylmalonyl-CoA mutase, large subunit K01848 - 5.4.99.2 8.756e-242 758.0
PYH3_k127_7624494_1 LAO AO transport system ATPase K07588 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000006138 258.0
PYH3_k127_7624494_2 methylmalonyl-CoA mutase C-terminal K01849 - 5.4.99.2 0.0000000000000000000000000000000000000000000000000000000009211 203.0
PYH3_k127_7624494_3 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000005448 126.0
PYH3_k127_7624494_4 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000215 44.0
PYH3_k127_7655869_0 amine dehydrogenase activity - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001349 276.0
PYH3_k127_7655869_1 Peptidase family M48 K03799 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000001709 271.0
PYH3_k127_7655869_2 transcription regulator activity - - - 0.0000000000000000000000000000000000000000292 156.0
PYH3_k127_7673441_0 4Fe-4S single cluster domain K07129 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003646 353.0
PYH3_k127_7673441_1 PFAM Amidohydrolase family K01468 - 3.5.2.7 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000997 332.0
PYH3_k127_7673441_2 Nucleotidyl transferase K00966 - 2.7.7.13 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000003993 297.0
PYH3_k127_7673441_3 Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits K02528 GO:0000154,GO:0000179,GO:0001510,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0008168,GO:0008170,GO:0008173,GO:0008649,GO:0008757,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0016433,GO:0016740,GO:0016741,GO:0022613,GO:0031167,GO:0032259,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0043412,GO:0043414,GO:0044085,GO:0044237,GO:0044238,GO:0044260,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0140098,GO:0140102,GO:1901360 2.1.1.182 0.000000000000000000000000000000000000000000000000000000000000008804 226.0
PYH3_k127_7673441_4 archaeal coiled-coil protein - - - 0.00000000000000000000000001362 123.0
PYH3_k127_7676963_0 Periplasmic copper-binding protein (NosD) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000001427 326.0
PYH3_k127_7676963_1 Cys/Met metabolism PLP-dependent enzyme - - - 0.00000000000000000000001763 105.0
PYH3_k127_7715014_0 Transglutaminase-like superfamily - - - 0.00000000000000000000000000000004646 143.0
PYH3_k127_7715014_1 Protein of unknown function (DUF3344) - - - 0.00000000000000000001603 106.0
PYH3_k127_7763095_0 Isocitrate/isopropylmalate dehydrogenase K00031 - 1.1.1.42 0.00000000000000000000000000000000000000000000000000000000000001897 216.0
PYH3_k127_7763095_1 4Fe-4S dicluster domain - - - 0.00000000000000000000000000000000000000000000002576 184.0
PYH3_k127_7788230_0 Domain in cystathionine beta-synthase and other proteins. - - - 0.000000000000000000000000000000000001176 149.0
PYH3_k127_7788230_1 PFAM AMMECR1 domain protein K09141 - - 0.00000000000000000000000000000000008773 147.0
PYH3_k127_7788230_2 PFAM 4-vinyl reductase, 4VR K07013 - - 0.00000000000001218 79.0
PYH3_k127_7788230_3 Roadblock LC7 family protein K07131 - - 0.000000000009191 72.0
PYH3_k127_7868448_0 Uncharacterized protein family (UPF0051) K09014 - - 3.832e-247 770.0
PYH3_k127_7868448_1 Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine K11717 - 2.8.1.7,4.4.1.16 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002007 492.0
PYH3_k127_7868448_2 FeS assembly protein SufD K07033,K09015 GO:0006790,GO:0006950,GO:0006979,GO:0008150,GO:0008152,GO:0009987,GO:0016043,GO:0016226,GO:0022607,GO:0031163,GO:0044085,GO:0044237,GO:0050896,GO:0051186,GO:0071840 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002855 429.0
PYH3_k127_7868448_3 ABC transporter K09013 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005171 378.0
PYH3_k127_7868448_4 NifU-like N terminal domain K04488 - - 0.0000000000000000000000000000000000000000000000000002033 189.0
PYH3_k127_7868448_5 Multicopper oxidase K00368 - 1.7.2.1 0.00000000000000000001098 93.0
PYH3_k127_7873313_0 PFAM ABC transporter related K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002388 362.0
PYH3_k127_7873313_1 TIGRFAM daunorubicin resistance ABC transporter, inner membrane subunit B K01992 - - 0.000000000000000000000000000000000000000000000000000000000000000000004238 242.0
PYH3_k127_7873313_2 AAA domain, putative AbiEii toxin, Type IV TA system K01990 - - 0.00000000000000000000000000000000000000000000000000000000002402 218.0
PYH3_k127_7873313_3 COG1277 ABC-type transport system involved in multi-copper enzyme maturation, permease component K01992,K19341 - - 0.00000000003263 76.0
PYH3_k127_787625_0 PFAM Multicopper oxidase - - - 1.635e-210 674.0
PYH3_k127_787625_1 PFAM Radical SAM domain protein K04070 - 1.97.1.4 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001545 494.0
PYH3_k127_787625_2 Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family K00826 - 2.6.1.42 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008263 360.0
PYH3_k127_787625_3 SAICAR synthetase K01923 - 6.3.2.6 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004407 360.0
PYH3_k127_787625_4 Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit K01902 - 6.2.1.5 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002255 347.0
PYH3_k127_787625_5 ATP-grasp domain K01903 - 6.2.1.5 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001493 347.0
PYH3_k127_787625_6 PFAM Circadian clock protein KaiC - - - 0.000000000000000000000000000000000000000000000000000000000000000007177 241.0
PYH3_k127_787625_7 Pfam:KaiC - - - 0.000000000000000000000000000000000000000001312 162.0
PYH3_k127_787625_8 DJ-1/PfpI family - - - 0.0000000000000000000000000000005919 130.0
PYH3_k127_7903547_0 GXGXG motif - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002775 617.0
PYH3_k127_7903547_1 Glutamate synthase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002799 595.0
PYH3_k127_7903547_2 glutamate synthase activity - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000001763 313.0
PYH3_k127_7910468_0 DEAD/H associated K03724 - - 6.603e-318 1022.0
PYH3_k127_7910468_1 acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase K01439 - 3.5.1.18 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001849 381.0
PYH3_k127_7912433_0 Catalyzes the sequential condensation of isopentenyl diphosphate (IPP) with geranylgeranyl diphosphate (GGPP) to yield (2Z,6Z,10Z,14Z,18Z,22Z,26Z,30E,34E,38E)-undecaprenyl diphosphate (tritrans,heptacis-UPP). It is probably the precursor of glycosyl carrier lipids K15888 GO:0002094,GO:0003674,GO:0003824,GO:0004659,GO:0006066,GO:0006629,GO:0006720,GO:0008150,GO:0008152,GO:0008299,GO:0008610,GO:0009058,GO:0009987,GO:0016093,GO:0016094,GO:0016740,GO:0016765,GO:0044237,GO:0044238,GO:0044249,GO:0044255,GO:0044281,GO:0044283,GO:0046165,GO:0071704,GO:1901576,GO:1901615,GO:1901617 2.5.1.89 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002916 335.0
PYH3_k127_7912433_1 ThiF family K21029 - 2.7.7.80 0.0000000000000000000000000000000000000000000000000000000000000000000000000000002567 273.0
PYH3_k127_7912433_2 Protein of unknown function TPD sequence-motif - - - 0.00000000000000000000000000000000000000000000000000000000121 210.0
PYH3_k127_7912433_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.0000000000000000000000000000000000000000000005221 173.0
PYH3_k127_7912433_4 ribonuclease activity K07060 - - 0.0000000000000000000000000000000135 132.0
PYH3_k127_7912709_0 Sodium pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for Na( ) movement across the membrane K15987 - 3.6.1.1 1.81e-206 660.0
PYH3_k127_7988504_0 PFAM RNA-metabolising metallo-beta-lactamase K12574 - - 0.000000000000000000000000000000000000000000000000000000000000000000008299 251.0
PYH3_k127_7988504_1 PFAM tRNA methyltransferase complex GCD14 subunit K07442 - 2.1.1.219,2.1.1.220 0.00000000000000000000000000000000000000000009581 169.0
PYH3_k127_7988504_2 PRC-barrel domain - - - 0.00000000000000000001472 93.0
PYH3_k127_7988504_3 - - - - 0.00000000006735 67.0
PYH3_k127_7988504_4 metallocarboxypeptidase activity K00368,K22348,K22349 - 1.16.3.3,1.7.2.1 0.000000004813 68.0
PYH3_k127_8011903_0 PFAM helicase domain protein - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002395 526.0
PYH3_k127_8035053_0 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000003677 231.0
PYH3_k127_8035053_1 - - - - 0.000000000000000000000000000000001302 149.0
PYH3_k127_8079710_0 Fibronectin-binding protein A N-terminus (FbpA) - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004592 349.0
PYH3_k127_8096831_0 Peptidase family M3 K01392 - 3.4.24.15 2.389e-203 654.0
PYH3_k127_8096831_1 ATPases associated with a variety of cellular activities K01990,K11050 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006882 325.0
PYH3_k127_8096831_2 ABC-type multidrug transport system, permease component K01992 - - 0.0000000000000000000000000000000000000009211 168.0
PYH3_k127_812865_0 Cation transporter/ATPase, N-terminus K01531 - 3.6.3.2 1.307e-286 904.0
PYH3_k127_8150441_0 DNA polymerase type-B family K02319 - 2.7.7.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004746 490.0
PYH3_k127_8150441_1 GTPase of unknown function C-terminal K06942 GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0044424,GO:0044464 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001168 408.0
PYH3_k127_8150441_2 Toxic component of a toxin-antitoxin (TA) module. An RNase - - - 0.00000000007948 67.0
PYH3_k127_8174894_0 Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur K03146 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007806 365.0
PYH3_k127_8174894_1 - - - - 0.00000000000000000000000000000000000000000008205 171.0
PYH3_k127_8174894_2 PFAM alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen K03564 - 1.11.1.15 0.0000000000000000000000000000000000002574 147.0
PYH3_k127_8175442_0 SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'- 5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity K03547 - - 0.0000000000000000000000000668 119.0
PYH3_k127_8175442_1 Part of the Rad50 Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50 Mre11 complex K03546 - - 0.00000000000002218 86.0
PYH3_k127_8311794_0 Catalyzes the synthesis of GMP from XMP K01951 GO:0003674,GO:0003824,GO:0003921,GO:0003922,GO:0006139,GO:0006163,GO:0006164,GO:0006177,GO:0006725,GO:0006753,GO:0006793,GO:0006796,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009116,GO:0009117,GO:0009119,GO:0009123,GO:0009124,GO:0009126,GO:0009127,GO:0009150,GO:0009152,GO:0009156,GO:0009161,GO:0009163,GO:0009165,GO:0009167,GO:0009168,GO:0009259,GO:0009260,GO:0009987,GO:0016874,GO:0016879,GO:0016884,GO:0018130,GO:0019438,GO:0019637,GO:0019693,GO:0034404,GO:0034641,GO:0034654,GO:0042278,GO:0042451,GO:0042455,GO:0044237,GO:0044238,GO:0044249,GO:0044271,GO:0044281,GO:0044283,GO:0046037,GO:0046128,GO:0046129,GO:0046390,GO:0046483,GO:0055086,GO:0071704,GO:0072521,GO:0072522,GO:0090407,GO:1901068,GO:1901070,GO:1901135,GO:1901137,GO:1901293,GO:1901360,GO:1901362,GO:1901564,GO:1901566,GO:1901576,GO:1901657,GO:1901659 6.3.5.2 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001939 436.0
PYH3_k127_8311794_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.000000000000000000000000000000000000000000000000000000001462 210.0
PYH3_k127_8348858_0 Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine K00764 - 2.4.2.14 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002107 544.0
PYH3_k127_8348858_1 PFAM aldo keto reductase - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000008952 282.0
PYH3_k127_8348858_2 Endoribonuclease L-PSP K09022 - 3.5.99.10 0.0000000000000000000000000001775 121.0
PYH3_k127_8348858_3 snRNP Sm proteins K04796 GO:0006139,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0034641,GO:0043170,GO:0044237,GO:0044238,GO:0046483,GO:0071704,GO:0090304,GO:1901360 - 0.0000000000000000000006205 98.0
PYH3_k127_8348858_4 Binds to the 23S rRNA K02922 - - 0.00000000000000000005934 90.0
PYH3_k127_8348858_5 KR domain K00034 - 1.1.1.47 0.0000000000000002093 86.0
PYH3_k127_8364473_0 PFAM amine oxidase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001552 432.0
PYH3_k127_8364473_1 Phosphomethylpyrimidine kinase K21219 - 2.5.1.3,2.7.1.49,2.7.4.7 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000151 372.0
PYH3_k127_8364473_2 COG0438 Glycosyltransferase K19002 - 2.4.1.337 0.0000000000000000000000000000000000000000000000000000000000000000000000000000001755 278.0
PYH3_k127_8364473_3 Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester K01975 - 3.1.4.58 0.00000000000000000000000000000000003569 141.0
PYH3_k127_8364473_4 Glycosyl transferase family 21 - - - 0.000000000000000000000000000001966 139.0
PYH3_k127_8364473_5 - - - - 0.0000000000000000000000000065 114.0
PYH3_k127_8378014_0 amino acid - - - 0.000000000000000000000000000000000000000003191 166.0
PYH3_k127_8378014_1 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000000159 132.0
PYH3_k127_8378014_2 Peptidase A24B, FlaK domain protein K07991 - 3.4.23.52 0.00000000007233 73.0
PYH3_k127_8406805_0 SPFH domain-Band 7 family - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000003485 276.0
PYH3_k127_8406805_1 - - - - 0.0000000000000000000000000000002555 130.0
PYH3_k127_8416686_0 PFAM Major facilitator superfamily - - - 0.00000000000000000000000000000000001472 144.0
PYH3_k127_8416686_1 Peptidase family M54 K06974 - - 0.00000000000000000000000000005473 120.0
PYH3_k127_8416686_2 Thiamine-binding protein - - - 0.000000000000000000000000001205 115.0
PYH3_k127_8416686_3 O-methyltransferase activity K03183,K15256 - 2.1.1.163,2.1.1.201 0.0000000000000001087 89.0
PYH3_k127_842169_0 PFAM Copper binding proteins, plastocyanin azurin family - - - 0.0000000005357 67.0
PYH3_k127_842169_2 Major facilitator Superfamily K07552,K19577 - - 0.000361 53.0
PYH3_k127_8472332_0 Protein of unknown function (DUF835) - - - 0.000000001108 71.0
PYH3_k127_8472332_1 peptidoglycan-associated (lipo)protein - - - 0.000009078 57.0
PYH3_k127_8482846_0 Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate K01497 - 3.5.4.25 0.000000000000000000000000000000000000000000000000000000000000000000001103 241.0
PYH3_k127_8482846_1 Protein of unknown function (DUF531) K09725 - - 0.000000000000000000000000000000000000000000000000004219 194.0
PYH3_k127_8482846_2 Biotin carboxyl carrier protein - - - 0.000000000000000004067 91.0
PYH3_k127_8482846_3 Protein-tyrosine phosphatase K14165 - 3.1.3.16,3.1.3.48 0.000000000000002023 83.0
PYH3_k127_8529740_0 Domain of unknown function DUF87 K06915 - - 0.000000000000000000000000000000000000000000000000000000000000004257 237.0
PYH3_k127_8529740_1 Helix-hairpin-helix DNA-binding motif class 1 - - - 0.0000000000000000000000000001203 118.0
PYH3_k127_8529740_2 Putative exonuclease SbcCD, C subunit K03546 - - 0.000000000000484 82.0
PYH3_k127_8529740_3 NurA - - - 0.000008155 58.0
PYH3_k127_854128_0 Tetratricopeptide TPR_2 repeat protein K06877 - - 0.000000000000000000001116 112.0
PYH3_k127_854128_1 PFAM Protein kinase domain - - - 0.0000002412 59.0
PYH3_k127_86161_0 Insulinase (Peptidase family M16) K07263 - - 0.00000000000000000000000000000000000000001151 160.0
PYH3_k127_86161_1 COG1599 Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins K07466 - - 0.0000000000000000000000000000000000004438 146.0
PYH3_k127_86161_2 Winged helix DNA-binding domain - - - 0.0000000000000000001055 92.0
PYH3_k127_86161_3 COG2146 Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases - - - 0.0000002048 57.0
PYH3_k127_8618522_0 DEAD/H associated K03724 - - 1.597e-219 703.0
PYH3_k127_8628987_0 Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone K03168 - 5.99.1.2 9.656e-215 692.0
PYH3_k127_8628987_1 Metallo-beta-lactamase superfamily - - - 0.000000000000000000000000000000000000000009552 156.0
PYH3_k127_8648850_0 DnaB-like helicase C terminal domain - - - 0.0000000000000000000002096 106.0
PYH3_k127_8648850_1 regulation of nucleus size - GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0006996,GO:0006997,GO:0008150,GO:0009987,GO:0016043,GO:0031974,GO:0031981,GO:0032535,GO:0034399,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0043233,GO:0044422,GO:0044424,GO:0044428,GO:0044446,GO:0044464,GO:0065007,GO:0065008,GO:0070013,GO:0071840,GO:0090066,GO:0097298 - 0.0001181 52.0
PYH3_k127_8664283_0 Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity K01409 GO:0000049,GO:0000408,GO:0002949,GO:0003674,GO:0003676,GO:0003723,GO:0003727,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006396,GO:0006399,GO:0006400,GO:0006725,GO:0006807,GO:0008033,GO:0008150,GO:0008152,GO:0009451,GO:0009987,GO:0010467,GO:0016070,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070525,GO:0071704,GO:0090304,GO:0097159,GO:1901360,GO:1901363 2.3.1.234 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000157 450.0
PYH3_k127_8664283_1 PFAM aminotransferase class V - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002014 348.0
PYH3_k127_8664283_2 PFAM ABC transporter K01990 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000004556 263.0
PYH3_k127_8664283_3 TIGRFAM CRISPR-associated protein Cas4 K07464 - 3.1.12.1 0.00000000000000000000000000000000000000000000403 171.0
PYH3_k127_8664283_4 - - - - 0.0000000002111 68.0
PYH3_k127_8664283_5 transcriptional regulators containing the CopG Arc MetJ DNA-binding domain - - - 0.0001095 50.0
PYH3_k127_8664283_6 - - - - 0.0007542 50.0
PYH3_k127_8675042_0 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005878 580.0
PYH3_k127_8675042_1 DUF35 OB-fold domain, acyl-CoA-associated K07068 - - 0.0000000000000000000000000000000000000000000000000004549 206.0
PYH3_k127_8675042_2 Thiolase, C-terminal domain K00626 - 2.3.1.9 0.0000000000000000000000000000000001874 136.0
PYH3_k127_8675042_3 Rubredoxin-like zinc ribbon domain (DUF35_N) K07068 - - 0.000000000000006644 84.0
PYH3_k127_868052_0 metallopeptidase activity K01179,K09607 GO:0003674,GO:0003824,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0016787,GO:0019538,GO:0043170,GO:0044238,GO:0071704,GO:0140096,GO:1901564 3.2.1.4 0.000004968 59.0
PYH3_k127_8680995_0 saccharopine dehydrogenase activity K19064 - 1.4.1.18 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006086 376.0
PYH3_k127_8680995_1 PFAM aldo keto reductase - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000008595 302.0
PYH3_k127_8680995_2 ABC-type multidrug transport system, ATPase component K01990 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000009334 259.0
PYH3_k127_8680995_3 ubiE/COQ5 methyltransferase family K00574,K07755 - 2.1.1.137,2.1.1.79 0.000000000000000000000000000000000000000000000000000000009402 206.0
PYH3_k127_8680995_4 Protein phosphatase 2C K17500 - 3.1.3.16 0.00000000000000000004033 105.0
PYH3_k127_8680995_5 PFAM transcriptional regulator TrmB - - - 0.000000000003113 76.0
PYH3_k127_8682250_0 Belongs to the UPF0282 family K07022 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000001109 261.0
PYH3_k127_8682250_1 FR47-like protein - - - 0.0000007653 56.0
PYH3_k127_8718227_0 phosphoglucomutase phosphomannomutase alpha beta alpha domain I K15778 - 5.4.2.2,5.4.2.8 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001475 457.0
PYH3_k127_8718227_1 Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. Acts as a genome stabilization factor that prevents flaps from equilibrating into structurs that lead to duplications and deletions. Also possesses 5'-3' exonuclease activity on nicked or gapped double-stranded DNA K04799 - - 0.0000000000000000000000000000000000000000000008371 170.0
PYH3_k127_8718227_2 Integral membrane protein DUF92 - - - 0.0000000000000000000000000000001732 137.0
PYH3_k127_8718227_3 COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon K00966,K16881 - 2.7.7.13,5.4.2.8 0.00007814 47.0
PYH3_k127_8733928_0 Zinc phosphodiesterase, which displays some tRNA 3'- processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA K00784 - 3.1.26.11 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000114 314.0
PYH3_k127_8733928_1 Aromatic amino acid lyase K01745 - 4.3.1.3 0.00000000000000000000000000000000000000000000000000005881 194.0
PYH3_k127_8735048_0 von Willebrand factor, type A - - - 0.000000000000000005976 98.0
PYH3_k127_8736213_0 DEAD DEAH box helicase domain protein K10896 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003069 473.0
PYH3_k127_8736213_1 TIGRFAM conserved repeat domain - - - 0.000000000000000000000000000000000000000001753 180.0
PYH3_k127_8740660_0 Catalytic component of the exosome, which is a complex involved in RNA degradation. Has 3'- 5' exoribonuclease activity. Can also synthesize heteropolymeric RNA-tails K11600 GO:0000177,GO:0000178,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009987,GO:0016070,GO:0016072,GO:0016075,GO:0019439,GO:0032991,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044444,GO:0044464,GO:0046483,GO:0046700,GO:0071704,GO:0090304,GO:1901360,GO:1901361,GO:1901575,GO:1902494,GO:1905354 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009795 337.0
PYH3_k127_8740660_1 Shwachman-Bodian-Diamond syndrome (SBDS) protein K14574 GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0016070,GO:0016072,GO:0022613,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0043170,GO:0044085,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:0097159,GO:1901360,GO:1901363 - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001471 291.0
PYH3_k127_8740660_2 Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Increases the RNA binding and the efficiency of RNA degradation. Confers strong poly(A) specificity to the exosome K03679 GO:0000178,GO:0000288,GO:0000291,GO:0000459,GO:0000460,GO:0000466,GO:0000467,GO:0000469,GO:0000956,GO:0003674,GO:0003676,GO:0003723,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0006139,GO:0006364,GO:0006396,GO:0006401,GO:0006402,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016070,GO:0016071,GO:0016072,GO:0016073,GO:0016074,GO:0016180,GO:0019222,GO:0019439,GO:0022613,GO:0031123,GO:0031125,GO:0031126,GO:0032991,GO:0034470,GO:0034472,GO:0034475,GO:0034641,GO:0034655,GO:0034660,GO:0034661,GO:0042254,GO:0043144,GO:0043170,GO:0043628,GO:0043928,GO:0044085,GO:0044237,GO:0044238,GO:0044248,GO:0044260,GO:0044265,GO:0044270,GO:0044424,GO:0044464,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0071034,GO:0071043,GO:0071051,GO:0071704,GO:0071840,GO:0090304,GO:0090305,GO:0090501,GO:0090503,GO:0097159,GO:1901360,GO:1901361,GO:1901363,GO:1901575,GO:1902494,GO:1905354 - 0.00000000000000000000000000000000000000000000000000000000000000001166 233.0
PYH3_k127_8740660_3 Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation K03432 GO:0000502,GO:0003674,GO:0003824,GO:0004175,GO:0005575,GO:0005622,GO:0005623,GO:0005839,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009056,GO:0009057,GO:0009987,GO:0010498,GO:0016787,GO:0019538,GO:0019773,GO:0030163,GO:0032991,GO:0043170,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044424,GO:0044464,GO:0051603,GO:0070011,GO:0071704,GO:0140096,GO:1901564,GO:1901565,GO:1901575,GO:1902494,GO:1905368,GO:1905369 3.4.25.1 0.0000000000000000000000000000000000000000000001677 171.0
PYH3_k127_8768537_0 4Fe-4S single cluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006252 314.0
PYH3_k127_8768537_1 COG3209 Rhs family protein - - - 0.000000000000006141 88.0
PYH3_k127_8768537_2 - - - - 0.0002042 51.0
PYH3_k127_8770559_0 aminopeptidase K01256 - 3.4.11.2 0.0000000000000000002618 93.0
PYH3_k127_8770559_1 LexA-binding, inner membrane-associated putative hydrolase K07038 - - 0.000000000000000003173 96.0
PYH3_k127_8780814_0 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000000008974 134.0
PYH3_k127_8780814_1 SMART Ras small GTPase, Ras type - - - 0.000000000000000000000000000004916 127.0
PYH3_k127_8780814_2 Two component regulator propeller - - - 0.000001314 61.0
PYH3_k127_8856520_0 NADH-Ubiquinone oxidoreductase (complex I), chain 5 N-terminus K00341 - 1.6.5.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001068 484.0
PYH3_k127_8856520_1 Proton-conducting membrane transporter K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003836 366.0
PYH3_k127_8856520_2 Evidence 2a Function of homologous gene experimentally demonstrated in an other organism K00342 - 1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000008348 364.0
PYH3_k127_8856520_3 electron donor, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory and or the photosynthetic chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation, and thus conserves the redox energy in a proton gradient K05572 GO:0006091,GO:0008150,GO:0008152,GO:0009987,GO:0015980,GO:0044237,GO:0045333,GO:0055114 1.6.5.3 0.0000000000000000000000000000000000000000000000000000000000000000000001319 256.0
PYH3_k127_8856520_4 NADH ubiquinone oxidoreductase subunit 11 or 4L (Chain K) K00340 - 1.6.5.3 0.0000000000000000006668 95.0
PYH3_k127_8856520_5 NADH-ubiquinone/plastoquinone oxidoreductase chain 6 K00339,K05578 - 1.6.5.3 0.00000000000007055 76.0
PYH3_k127_8856520_6 Respiratory-chain NADH dehydrogenase, 49 Kd subunit K22161 - 1.5.98.3 0.00000000001137 65.0
PYH3_k127_8858336_0 Malic enzyme, NAD binding domain K00027,K00029 - 1.1.1.38,1.1.1.40 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000006616 569.0
PYH3_k127_8858336_1 Proton-conducting membrane transporter K22169 - 1.5.98.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002521 329.0
PYH3_k127_8858336_2 Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP K03593 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002269 305.0
PYH3_k127_8897705_0 Fungalysin metallopeptidase (M36) - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000007093 297.0
PYH3_k127_8897705_1 DEAD DEAH box helicase domain protein K03724 - - 0.000000000000000000000000000000000000000001183 172.0
PYH3_k127_8903368_0 von Willebrand factor, type A - - - 0.000000000000001311 91.0
PYH3_k127_8903368_1 domain protein K20276 - - 0.00000005171 66.0
PYH3_k127_8951441_0 Belongs to the UPF0215 family K09120 - - 0.00000000000000000000000000000000000000003734 158.0
PYH3_k127_8951441_1 The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis K04794 - 3.1.1.29 0.00000000000000000000000000000000006148 148.0
PYH3_k127_8951441_2 Protein of unknown function (DUF1616) - - - 0.000000000000000000005244 102.0
PYH3_k127_8951441_4 Belongs to the UPF0273 family - - - 0.00000008695 57.0
PYH3_k127_8970909_0 eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA K03242 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004709 522.0
PYH3_k127_8970909_1 May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity K06965 GO:0000956,GO:0003674,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006401,GO:0006402,GO:0006412,GO:0006518,GO:0006725,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009056,GO:0009057,GO:0009058,GO:0009059,GO:0009892,GO:0009987,GO:0010467,GO:0010468,GO:0010605,GO:0010629,GO:0016043,GO:0016070,GO:0016071,GO:0016072,GO:0016075,GO:0019222,GO:0019439,GO:0019538,GO:0022411,GO:0032790,GO:0032984,GO:0032988,GO:0034641,GO:0034645,GO:0034655,GO:0034660,GO:0034661,GO:0043021,GO:0043022,GO:0043043,GO:0043170,GO:0043603,GO:0043604,GO:0043933,GO:0044237,GO:0044238,GO:0044248,GO:0044249,GO:0044260,GO:0044265,GO:0044267,GO:0044270,GO:0044271,GO:0044424,GO:0044464,GO:0044877,GO:0046483,GO:0046700,GO:0048519,GO:0050789,GO:0060255,GO:0065007,GO:0070651,GO:0070966,GO:0071704,GO:0071826,GO:0071840,GO:0090304,GO:1901360,GO:1901361,GO:1901564,GO:1901566,GO:1901575,GO:1901576,GO:1903008 - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000006586 286.0
PYH3_k127_8970909_2 Belongs to the eukaryotic ribosomal protein eS6 family K02991 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0005840,GO:0006139,GO:0006364,GO:0006396,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009987,GO:0010467,GO:0015935,GO:0016070,GO:0016072,GO:0022613,GO:0022626,GO:0022627,GO:0032991,GO:0034470,GO:0034641,GO:0034660,GO:0042254,GO:0042274,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0044085,GO:0044237,GO:0044238,GO:0044391,GO:0044422,GO:0044424,GO:0044444,GO:0044445,GO:0044446,GO:0044464,GO:0046483,GO:0071704,GO:0071840,GO:0090304,GO:1901360,GO:1990904 - 0.00000000000000000000000000000000001015 137.0
PYH3_k127_8970909_3 Belongs to the UPF0215 family K09120 - - 0.00001821 46.0
PYH3_k127_8970909_4 ADP-ribosylglycohydrolase - - - 0.0005002 48.0
PYH3_k127_9014499_0 Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity K03531 GO:0000166,GO:0001882,GO:0001883,GO:0003674,GO:0003824,GO:0003924,GO:0005488,GO:0005525,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0009987,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0017076,GO:0017111,GO:0019001,GO:0032153,GO:0032549,GO:0032550,GO:0032553,GO:0032555,GO:0032561,GO:0035639,GO:0036094,GO:0043167,GO:0043168,GO:0044424,GO:0044464,GO:0051301,GO:0097159,GO:0097367,GO:1901265,GO:1901363 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000004811 472.0
PYH3_k127_9014499_1 Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors K02867 GO:0000027,GO:0003674,GO:0003676,GO:0003723,GO:0003735,GO:0005198,GO:0005488,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005840,GO:0006412,GO:0006518,GO:0006807,GO:0006996,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009987,GO:0010467,GO:0016043,GO:0019538,GO:0019843,GO:0022607,GO:0022613,GO:0022618,GO:0032991,GO:0034622,GO:0034641,GO:0034645,GO:0042254,GO:0042255,GO:0042273,GO:0043043,GO:0043170,GO:0043226,GO:0043228,GO:0043229,GO:0043232,GO:0043603,GO:0043604,GO:0043933,GO:0044085,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044267,GO:0044271,GO:0044424,GO:0044444,GO:0044464,GO:0065003,GO:0070925,GO:0071704,GO:0071826,GO:0071840,GO:0097159,GO:1901363,GO:1901564,GO:1901566,GO:1901576,GO:1990904 - 0.000000000000000000000000000000000000000000000000000002257 194.0
PYH3_k127_9014499_2 Transcription elongation factor Spt5 K02601 GO:0003674,GO:0003676,GO:0003677,GO:0003723,GO:0003729,GO:0005488,GO:0006139,GO:0006351,GO:0006354,GO:0006355,GO:0006357,GO:0006366,GO:0006368,GO:0006396,GO:0006397,GO:0006725,GO:0006807,GO:0008150,GO:0008152,GO:0009058,GO:0009059,GO:0009889,GO:0009987,GO:0010467,GO:0010468,GO:0010556,GO:0016070,GO:0016071,GO:0018130,GO:0019219,GO:0019222,GO:0019438,GO:0031323,GO:0031326,GO:0032774,GO:0034641,GO:0034645,GO:0034654,GO:0043170,GO:0044237,GO:0044238,GO:0044249,GO:0044260,GO:0044271,GO:0046483,GO:0050789,GO:0050794,GO:0051171,GO:0051252,GO:0060255,GO:0065007,GO:0071704,GO:0080090,GO:0090304,GO:0097159,GO:0097659,GO:1901360,GO:1901362,GO:1901363,GO:1901576,GO:1903506,GO:2000112,GO:2001141 - 0.00000000000000000000000000000000000000000000000000000814 201.0
PYH3_k127_9014499_3 TIGRFAM protein translocase SEC61 complex gamma subunit K07342 - - 0.00000000000005779 75.0
PYH3_k127_915421_0 PFAM BadF BadG BcrA BcrD ATPase family - - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003343 425.0
PYH3_k127_915421_1 BadF/BadG/BcrA/BcrD ATPase family K04115 - 1.3.7.8 0.0000000000000000000000000000000000000000000000000000000000000000000000000002924 265.0
PYH3_k127_915421_10 - - - - 0.0005076 46.0
PYH3_k127_915421_11 SnoaL-like polyketide cyclase K07255 - - 0.0006974 53.0
PYH3_k127_915421_2 PFAM Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000000000000004214 225.0
PYH3_k127_915421_3 exonuclease of the beta-lactamase fold involved in RNA processing K07577 - - 0.00000000000000000000000000000002519 144.0
PYH3_k127_915421_4 4 iron, 4 sulfur cluster binding K00205,K02573 - - 0.000000000000000000000006005 115.0
PYH3_k127_915421_5 - - - - 0.0000000000000000000001406 103.0
PYH3_k127_915421_6 helix_turn_helix, Arsenical Resistance Operon Repressor - - - 0.0000000000000001856 87.0
PYH3_k127_915421_7 DNA-binding protein with PD1-like DNA-binding motif K06934 - - 0.0000000000000002771 86.0
PYH3_k127_915421_8 DNA alkylation repair enzyme - - - 0.0000000000003659 79.0
PYH3_k127_915421_9 Belongs to the glycosyl hydrolase 13 family - - - 0.000000065 63.0
PYH3_k127_9188921_0 DEAD/H associated K03724 GO:0003674,GO:0003724,GO:0003824,GO:0004004,GO:0004386,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0006139,GO:0006725,GO:0006807,GO:0008026,GO:0008150,GO:0008152,GO:0008186,GO:0009987,GO:0010501,GO:0016070,GO:0016462,GO:0016787,GO:0016817,GO:0016818,GO:0016887,GO:0017111,GO:0034641,GO:0042623,GO:0043170,GO:0044237,GO:0044238,GO:0044424,GO:0044464,GO:0046483,GO:0070035,GO:0071704,GO:0090304,GO:0140098,GO:1901360 - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000002011 594.0
PYH3_k127_9188921_1 Thiolase, N-terminal domain K00626 - 2.3.1.9 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000007017 466.0
PYH3_k127_9188921_2 PFAM 3-hydroxyacyl-CoA dehydrogenase, C-terminal domain K00074 - 1.1.1.157 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000003 367.0
PYH3_k127_9188921_3 Protein of unknown function (DUF1349) - - - 0.0000000000000000000000000000000000000000000000000000000006592 231.0
PYH3_k127_9188921_4 Is also involved in protein lipoylation via its role as an octanoyl lipoyl carrier protein intermediate K02437 - - 0.00000000000000000000000000000000000000000000004745 173.0
PYH3_k127_9188921_5 Bacterial Ig-like domain - - - 0.000000000000000000000000000004363 139.0
PYH3_k127_9188921_6 Methyltransferase type 11 - - - 0.00000000000000000000000000001367 124.0
PYH3_k127_9222850_0 PFAM AMP-dependent synthetase K01897 - 6.2.1.3 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001057 403.0
PYH3_k127_9222850_1 Acyl-coenzyme A:6-aminopenicillanic acid acyl-transferase K19200 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000315 313.0
PYH3_k127_9222850_2 Acetyltransferase (GNAT) family - - - 0.000000000000000000000000000000000000000000000000000000000000001138 243.0
PYH3_k127_9222850_3 Acetyltransferase (GNAT) family - - - 0.0000000000000000000000000000000000000000000000000000000000003615 225.0
PYH3_k127_9222850_4 Winged helix DNA-binding domain - - - 0.0000000000000000000000000000000000000000123 163.0
PYH3_k127_9302800_0 Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate K15635 - 5.4.2.12 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001682 434.0
PYH3_k127_9302800_1 S-adenosyl-l-methionine hydroxide adenosyltransferase K22205 - - 0.000000000000000000000000000000000000000000000000000000000003841 221.0
PYH3_k127_9322875_0 Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family K07250 - 2.6.1.19,2.6.1.22 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001075 447.0
PYH3_k127_9322875_1 Saccharopine dehydrogenase C-terminal domain K00290 - 1.5.1.7 0.0000000000000000000000000000000000000000000000000000000002353 230.0
PYH3_k127_9322875_2 Major Facilitator Superfamily - - - 0.0000000000000000000000000000000000000000000000000001504 202.0
PYH3_k127_9322875_3 Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS K03151 - 2.8.1.4 0.000000000000000000000000000000000000000000000002872 184.0
PYH3_k127_9322875_4 membrane transporter protein K07090 - - 0.00000000000000000036 97.0
PYH3_k127_9332835_0 Putative modulator of DNA gyrase K03568 - - 0.00000000000000000000000000000000000000000000000596 181.0
PYH3_k127_9332835_1 COG0023 Translation initiation factor 1 (eIF-1 SUI1) and related proteins K03113 - - 0.000000000000000000001853 98.0
PYH3_k127_9332835_2 PFAM PKD domain - - - 0.0000000001087 74.0
PYH3_k127_933854_0 it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids K02313 - - 0.0000000000000000000000000000000000000000000000000000000000000000000000000005181 280.0
PYH3_k127_933854_1 - - - - 0.000005126 52.0
PYH3_k127_933854_2 Peptidase family C25 K03546,K20074 - 3.1.3.16 0.00004345 54.0
PYH3_k127_9345333_0 Catalyzes the formation of CDP-2,3-bis-(O- geranylgeranyl)-sn-glycerol (CDP-archaeol) from 2,3-bis-(O- geranylgeranyl)-sn-glycerol 1-phosphate (DGGGP) and CTP. This reaction is the third ether-bond-formation step in the biosynthesis of archaeal membrane lipids K19664 - 2.7.7.67 0.0000000000000000000000000000000000000000000001573 177.0
PYH3_k127_9345333_1 DnaB-like helicase C terminal domain - - - 0.000000000000000000000000000000000005028 146.0
PYH3_k127_9403850_0 Belongs to the V-ATPase 116 kDa subunit family K02123 - - 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000121 316.0
PYH3_k127_9403850_1 Produces ATP from ADP in the presence of a proton gradient across the membrane K02119 - - 0.00000000000000000000000000000000000000005134 160.0
PYH3_k127_9403850_2 PFAM FAD linked oxidase domain protein K00104 - 1.1.3.15 0.00000000000000000000000004518 121.0
PYH3_k127_9403850_3 Produces ATP from ADP in the presence of a proton gradient across the membrane K02121 - - 0.00000000000000001065 90.0
PYH3_k127_9403850_4 ATP synthase subunit C K02124 - - 0.0000008214 53.0
PYH3_k127_9403850_5 FAD linked oxidases, C-terminal domain K00102 - 1.1.2.4 0.000002058 61.0
PYH3_k127_9478197_0 - - - - 0.000000000000000000000000001391 120.0
PYH3_k127_9478197_1 Contacts the emerging nascent chain on the ribosome K03626 - - 0.0000000000000000001913 94.0
PYH3_k127_9556156_0 Membrane bound hydrogenase subunit K18016 - 1.12.7.2 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000089 475.0
PYH3_k127_9556156_1 Component of the F(420)H(2) dehydrogenase (FPO complex) which is part of the energy-conserving F(420)H(2) heterodisulfide oxidoreductase system. The membrane-bound electron transfer system of the complex plays an important role in the metabolism of methylotrophic methanogens when the organisms grow on methanol or methylamines. Catalyzes the oxidation of methanophenazine to dihydromethanophenazine. It shuttles electrons from F(420)H(2), via FAD and iron-sulfur (Fe-S) centers, to methanophenazine (an electron carrier in the membrane). It couples the redox reaction to proton translocation (for every two electrons transferred, two hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient K00337,K22163 - 1.5.98.3,1.6.5.3 0.00000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001927 349.0
PYH3_k127_9556156_2 Hydrogenase maturation protease K08315 GO:0003674,GO:0003824,GO:0004175,GO:0006464,GO:0006508,GO:0006807,GO:0008150,GO:0008152,GO:0008233,GO:0009987,GO:0010467,GO:0016485,GO:0016787,GO:0019538,GO:0036211,GO:0043170,GO:0043412,GO:0044237,GO:0044238,GO:0044260,GO:0044267,GO:0051604,GO:0070011,GO:0071704,GO:0140096,GO:1901564 3.4.23.51 0.000000000000000000000000000000001874 136.0
PYH3_k127_9556156_3 Respiratory-chain NADH dehydrogenase, 30 Kd subunit K22160 - 1.5.98.3 0.000000000000000000000000000005554 122.0
PYH3_k127_9556156_4 Formate hydrogenlyase subunit 6 NADH ubiquinone oxidoreductase 23 kD subunit (chain I) K00338 - 1.6.5.3 0.00000000000000000000000003166 117.0
PYH3_k127_9556156_5 CAAX protease self-immunity - - - 0.0000000000003741 83.0
PYH3_k127_9567624_0 ABC transporter K06158 - - 0.00000000000000000000000000000000000000000000000000005965 201.0
PYH3_k127_9567624_1 - - - - 0.00000000000000000000003465 111.0
PYH3_k127_9567624_2 Aspartyl protease - - - 0.0000000000000002233 85.0
PYH3_k127_9567624_3 Repeats in polycystic kidney disease 1 (PKD1) and other proteins - - - 0.000000001012 70.0
PYH3_k127_9588737_0 Anticodon-binding domain of tRNA K01873 - 6.1.1.9 2.729e-222 712.0
PYH3_k127_9588737_1 ATPases associated with a variety of cellular activities K02003 - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000001894 287.0
PYH3_k127_9588737_2 SMART Ras small GTPase, Ras type - - - 0.00000000000000000000000000000002534 134.0
PYH3_k127_9588737_3 Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol K15520 GO:0000302,GO:0003674,GO:0003824,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005829,GO:0006790,GO:0006950,GO:0006979,GO:0008080,GO:0008150,GO:0008152,GO:0009058,GO:0009268,GO:0009628,GO:0009636,GO:0009987,GO:0010035,GO:0010125,GO:0010126,GO:0010447,GO:0016137,GO:0016138,GO:0016407,GO:0016410,GO:0016740,GO:0016746,GO:0016747,GO:0033554,GO:0034599,GO:0034614,GO:0035447,GO:0035690,GO:0040007,GO:0042221,GO:0042493,GO:0042542,GO:0044110,GO:0044116,GO:0044117,GO:0044119,GO:0044237,GO:0044249,GO:0044272,GO:0044403,GO:0044419,GO:0044424,GO:0044444,GO:0044464,GO:0046677,GO:0050896,GO:0051186,GO:0051188,GO:0051704,GO:0051716,GO:0070301,GO:0070887,GO:0071214,GO:0071236,GO:0071467,GO:0071468,GO:0071704,GO:0097237,GO:0104004,GO:1901135,GO:1901137,GO:1901576,GO:1901657,GO:1901659,GO:1901700,GO:1901701 2.3.1.189 0.000002119 59.0
PYH3_k127_9588737_4 M6 family metalloprotease domain protein - - - 0.00004886 53.0
PYH3_k127_9591364_0 Peptidase family M50 - - - 0.000000000000000000000000000000000000000000000000000000000000004903 233.0
PYH3_k127_9591364_1 Belongs to the MEMO1 family K06990 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0008150,GO:0032886,GO:0044424,GO:0044464,GO:0050789,GO:0050794,GO:0065007 - 0.000000000000000000000000000000000000000000005914 166.0
PYH3_k127_9591364_2 - - - - 0.0000000000000000000000009309 108.0
PYH3_k127_9591364_3 Belongs to the UPF0273 family - - - 0.000000000000001054 86.0
PYH3_k127_9673138_0 Thioredoxin - - - 0.000000000000000001343 92.0
PYH3_k127_9693527_0 COG0022 Pyruvate 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit K00162 - 1.2.4.1 0.0000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000009956 423.0
PYH3_k127_9693527_1 metaphase/anaphase transition of mitotic cell cycle K03350 GO:0000003,GO:0000070,GO:0000151,GO:0000152,GO:0000209,GO:0000278,GO:0000280,GO:0000375,GO:0000377,GO:0000398,GO:0000819,GO:0001775,GO:0003002,GO:0003006,GO:0003674,GO:0003676,GO:0003677,GO:0003824,GO:0004842,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005654,GO:0005680,GO:0005737,GO:0005813,GO:0005815,GO:0005819,GO:0005829,GO:0005856,GO:0006139,GO:0006396,GO:0006397,GO:0006464,GO:0006508,GO:0006511,GO:0006725,GO:0006807,GO:0006810,GO:0006887,GO:0006996,GO:0007049,GO:0007050,GO:0007059,GO:0007088,GO:0007091,GO:0007275,GO:0007338,GO:0007343,GO:0007346,GO:0007389,GO:0008150,GO:0008152,GO:0008283,GO:0008356,GO:0008380,GO:0009056,GO:0009057,GO:0009504,GO:0009566,GO:0009653,GO:0009719,GO:0009725,GO:0009733,GO:0009790,GO:0009791,GO:0009793,GO:0009798,GO:0009888,GO:0009896,GO:0009933,GO:0009948,GO:0009949,GO:0009952,GO:0009987,GO:0010014,GO:0010015,GO:0010033,GO:0010071,GO:0010154,GO:0010467,GO:0010498,GO:0010564,GO:0010638,GO:0010965,GO:0015630,GO:0016043,GO:0016070,GO:0016071,GO:0016192,GO:0016567,GO:0016740,GO:0017156,GO:0019538,GO:0019787,GO:0019899,GO:0019902,GO:0019903,GO:0019941,GO:0019953,GO:0022402,GO:0022414,GO:0022622,GO:0030071,GO:0030154,GO:0030163,GO:0031145,GO:0031331,GO:0031461,GO:0031974,GO:0031981,GO:0032270,GO:0032436,GO:0032446,GO:0032501,GO:0032502,GO:0032940,GO:0032991,GO:0033043,GO:0033044,GO:0033045,GO:0033047,GO:0034399,GO:0034641,GO:0036211,GO:0042221,GO:0043161,GO:0043170,GO:0043226,GO:0043227,GO:0043228,GO:0043229,GO:0043231,GO:0043232,GO:0043233,GO:0043412,GO:0043632,GO:0043900,GO:0043901,GO:0044237,GO:0044238,GO:0044248,GO:0044257,GO:0044260,GO:0044265,GO:0044267,GO:0044422,GO:0044424,GO:0044428,GO:0044430,GO:0044444,GO:0044446,GO:0044464,GO:0044703,GO:0044770,GO:0044772,GO:0044784,GO:0045055,GO:0045732,GO:0045786,GO:0045787,GO:0045840,GO:0045842,GO:0045862,GO:0045930,GO:0045931,GO:0046483,GO:0046903,GO:0048285,GO:0048316,GO:0048364,GO:0048507,GO:0048508,GO:0048518,GO:0048519,GO:0048522,GO:0048523,GO:0048532,GO:0048608,GO:0048731,GO:0048829,GO:0048856,GO:0048869,GO:0050789,GO:0050794,GO:0050896,GO:0051128,GO:0051130,GO:0051179,GO:0051234,GO:0051247,GO:0051276,GO:0051301,GO:0051603,GO:0051704,GO:0051726,GO:0051781,GO:0051783,GO:0051785,GO:0051983,GO:0051984,GO:0060467,GO:0060468,GO:0060471,GO:0061458,GO:0061630,GO:0061659,GO:0062033,GO:0065001,GO:0065007,GO:0070013,GO:0070647,GO:0070979,GO:0071704,GO:0071840,GO:0071849,GO:0071850,GO:0071851,GO:0080154,GO:0090068,GO:0090304,GO:0090421,GO:0097159,GO:0098813,GO:0099402,GO:0140014,GO:0140096,GO:1901360,GO:1901363,GO:1901564,GO:1901565,GO:1901575,GO:1901800,GO:1901970,GO:1901987,GO:1901989,GO:1901990,GO:1901992,GO:1902099,GO:1902101,GO:1902494,GO:1903047,GO:1903052,GO:1903364,GO:1905392,GO:1905818,GO:1905820,GO:1990234,GO:2000241,GO:2000242,GO:2001252 - 0.000002867 57.0
PYH3_k127_9702949_0 Radical_SAM C-terminal domain K07739 GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0044424,GO:0044464 2.3.1.48 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000001407 539.0
PYH3_k127_9702949_1 PFAM tRNA synthetase, class II (G, H, P and S) K01880 GO:0003674,GO:0003824,GO:0004812,GO:0004820,GO:0005488,GO:0005515,GO:0016874,GO:0016875,GO:0046983,GO:0140098,GO:0140101 6.1.1.14 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000005354 379.0
PYH3_k127_9702949_10 Domain of unknown function DUF11 - - - 0.00000000002264 78.0
PYH3_k127_9702949_11 OmpA family - - - 0.00000000002654 77.0
PYH3_k127_9702949_12 OmpA family - - - 0.00000000002983 78.0
PYH3_k127_9702949_13 OmpA family K02557,K03286 - - 0.0000000001278 72.0
PYH3_k127_9702949_2 Domain in cystathionine beta-synthase and other proteins. - - - 0.00000000000000000000000000000000000000000000000000000000000000000000000001874 261.0
PYH3_k127_9702949_3 Amidohydrolase family K01485,K01487 - 3.5.4.1,3.5.4.3 0.00000000000000000000000000000000000000000000000000000000000001049 231.0
PYH3_k127_9702949_4 DNA-binding transcription factor activity - - - 0.0000000000000000000000000000000000000000000000003268 180.0
PYH3_k127_9702949_5 Belongs to the GTP cyclohydrolase I type 2 NIF3 family - - - 0.0000000000000000000000000000000000000003485 153.0
PYH3_k127_9702949_6 Rab subfamily of small GTPases K07874 GO:0000139,GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005737,GO:0005794,GO:0005802,GO:0005886,GO:0006810,GO:0006888,GO:0008092,GO:0008150,GO:0012505,GO:0016020,GO:0016192,GO:0017022,GO:0030742,GO:0031090,GO:0031984,GO:0032029,GO:0032036,GO:0032588,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044422,GO:0044424,GO:0044431,GO:0044444,GO:0044446,GO:0044464,GO:0046907,GO:0048193,GO:0051179,GO:0051234,GO:0051641,GO:0051649,GO:0071944,GO:0080115,GO:0098588,GO:0098791 - 0.0000000000000000000000003508 116.0
PYH3_k127_9702949_7 Domain of unknown function DUF11 - - - 0.000000000000000000000001447 121.0
PYH3_k127_9702949_8 OmpA family - - - 0.0000000000000002852 91.0
PYH3_k127_9702949_9 - - - - 0.00000000001575 70.0
PYH3_k127_9718530_0 4Fe-4S dicluster domain - - - 0.000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000000018 434.0
PYH3_k127_9718530_1 pterin-4-alpha-carbinolamine dehydratase K01724 - 4.2.1.96 0.0000000000000000000000000702 109.0
PYH3_k127_9718530_2 negative regulation of heat generation - GO:0003674,GO:0005488,GO:0005515,GO:0005575,GO:0005622,GO:0005623,GO:0005634,GO:0005737,GO:0008150,GO:0009892,GO:0010468,GO:0010605,GO:0010629,GO:0019222,GO:0019899,GO:0019902,GO:0019903,GO:0030346,GO:0043226,GO:0043227,GO:0043229,GO:0043231,GO:0044424,GO:0044464,GO:0048519,GO:0050789,GO:0060255,GO:0065007 - 0.000000002487 68.0